CN104984114A - Traditional Chinese medicine capsule for treating children bronchial asthma - Google Patents
Traditional Chinese medicine capsule for treating children bronchial asthma Download PDFInfo
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- CN104984114A CN104984114A CN201510371917.7A CN201510371917A CN104984114A CN 104984114 A CN104984114 A CN 104984114A CN 201510371917 A CN201510371917 A CN 201510371917A CN 104984114 A CN104984114 A CN 104984114A
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Abstract
The invention discloses a traditional Chinese medicine capsule for treating children bronchial asthma. The capsule is prepared from the following traditional Chinese medicinal materials in parts by weight: 20 parts of radix astragali, 15 parts of radix codonopsis, 12 parts of phragmititis caulis, 8 parts of ephedra, 6 parts of radix glycyrrhizae, 13 parts of nidus vespae, 4 parts of dried bodies of buthus martensii karsch, 3 parts of centipede, 7 parts of roots of agapetes burmanica, 8 parts of lophatherum gracile, 5 parts of piper sarmentosum roxb, 6 parts of wild semen canavaliae, 8 parts of rhizoma polygonati, 8 parts of roots of straight ladybell, 6 parts of radix ophiopogonis, 8 parts of fructus lycii, 6 parts of radix paeoniae alba and 5 parts of pine pollen disruption powder. Proved by clinical experiments, through the selection of appropriate medicinal materials and proportion thereof, the capsule achieves the remarkable efficacy of treating children bronchial asthma, and is safe and free of toxic and side effects.
Description
Technical field
the present invention relates to a kind of Chinese medicinal capsule, be specifically related to a kind of Chinese medicinal capsule being used for the treatment of bronchial asthma of child.
Background technology
bronchial asthma of child, wheezing tachypnea when facing card to show effect, be feature with cough and expectorant sound, because children's's internal organs are tender and lovely, skin is dredged thin, and cold warming up does not know self-regulated, is difficult to the change adapting to external environment, very easily being invaded by exogenous pathogen.Again " lung occupies the part of the body cavity above the diaphragm housing the heart and lungs, is the canopy of the vital organs of the human body, and exopathogen is attacked, and lung stands in the breach ", so that evil strongly fragrant in lung meridian, block lung network, cause lung qi a surname to fall not normal, ascending or descending movement of vital Qi is unfavorable, occurs that a series of asthma clinical shows.Treatment for bronchial asthma of child still lacks the effective medicine of generally recognized as safe at present.
Summary of the invention
the present invention aims to provide a kind of Chinese medicinal capsule being used for the treatment of bronchial asthma of child and preparation method thereof, by selecting suitable medical material and proportioning thereof, reaches the remarkable efficacy contributing to treating bronchial asthma of child, and safe without toxic side effect.
in order to achieve the above object, the present invention is by the following technical solutions:
be used for the treatment of a Chinese medicinal capsule for bronchial asthma of child, be prepared from by the Chinese crude drug of following weight proportion: the Radix Astragali 20 parts, Radix Codonopsis 15 parts, Rhizoma Phragmitis 12 parts, 8 parts, Herba Ephedrae, 6 parts, Radix Glycyrrhizae, 13 parts, Discolia Vittifrons Sch. room, Scorpio 4 parts, Scolopendra 3 parts, wart bag spend 7 parts, Herba Lophatheri 8 parts, Piper longum dish 5 parts, wild Semen Canavaliae 6 parts, Rhizoma Polygonati 8 parts, Radix Adenophorae (Radix Glehniae) 8 parts, Radix Ophiopogonis 6 parts, Fructus Lycii 8 parts, the Radix Paeoniae Alba 6 parts, breaking cellular wall Pollen Pini 5 parts.
preparation method is: mix after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.
the pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
the dry root of the Radix Astragali [source] leguminous plant Radix Astagali.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
radix Codonopsis [source] this product is the dry root of Campanulaceae Radix Codonopsis.[nature and flavor] are sweet, flat.[return through] returns spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
the tender stem that Rhizoma Phragmitis [source] is grass phragmites communis.[nature and flavor] are sweet, cold, nontoxic.[return through] enters the heart, lung.[function cures mainly] controls lung abscess dysphoria with smothery sensation.
herba Ephedrae [source] this product is the dry herb stem of Ephedraceae plant plait Herba Ephedrae.[nature and flavor] pungent, micro-hardship, temperature.[return through] returns lung, urinary bladder channel.[function cures mainly] diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema; Bronchial asthma.
radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
discolia Vittifrons Sch. room [source] is the nest of the red stricture of vagina Discolia Vittifrons Sch. of Scoliidae animal.[nature and flavor] mildly bitter flavor, warm in nature.[function cures mainly] Qinghuo Jiedu, detumescence of dispeling the wind, stimulating milk secretion, cough-relieving flush end, leukorrhagia stopping.Cure mainly furuncle carbuncle furuncle abscess, innominate toxic swelling, skin erythema pruritus, galactostasis, cough, asthma, profuse leukorrhea.
scorpio [source] this product is the dry body of Buthidae animal Scorpio.[nature and flavor] are pungent, flat; Poisonous.[return through] returns Liver Channel.[function cures mainly] endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
the dry body of Scolopendra [source] Scolopendridae animal Scolopendpa Subspinipes Mutilans L. KOCH.[nature and flavor] are pungent, temperature; Poisonous.[return through] returns Liver Channel.[function cures mainly] endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.
the tuber that wart bag flower [source] is Vacciniaceae plant Burma Agapetes neriifolia (King et Prain) Airv-Shaw.[nature and flavor] mildly bitter flavor, puckery, cool in nature.[function cures mainly] adjusts benefit four tower, expelling wind and removing dampness, reducing swelling and alleviating pain, promoting the function of the gallbladder to alleviate jaundice, relieving cough and resolving phlegm.Cure mainly puerperal weak and sickly, weak, arthralgia due to wind-cold dampness, limbs joint pain, joint stuffiness, traumatic injury, innominate toxic swelling, cough with copious phlegm.
herba Lophatheri [source] this product is the dry stem and leaf of grass Herba Lophatheri.[nature and flavor] are sweet, light, cold.[return through] GUIXIN, stomach, small intestine meridian.[function cures mainly] clearing heat and relieving fidgetness, diuresis.For calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.
the Herb that Piper longum dish [source] is Piperaceae plant Radix Piperis sarmentosi (Herba Piperis Sarmentosi) or root, leaf, really.[nature and flavor] sweet in the mouth, gas delicate fragrance, property is put down.[function cures mainly] Qinghuo Jiedu, killing parasites for relieving itching, except wind pain relieving, cooling blood for hemostasis.Cure mainly toothache, alimentary toxicosis, nausea and vomiting, scabies, tinea, arthralgia due to wind-cold-dampness disease, limbs joint is ached, joint stuffiness, menoxenia, metrorrhagia.
the seed of the wild Semen Canavaliae of wild Semen Canavaliae [source] leguminous plant and root.[nature and flavor] taste is sweet.Property is put down.Enter four towers.[function cures mainly] adjusts benefit four tower, Qinghuo Jiedu, killing parasites for relieving itching.Cure mainly have a delicate constitution how sick, weak, anorexia, insomnia, furuncle carbuncle furuncle abscess, skin pruritus, macule, scabies, eczema.
rhizoma Polygonati [source] medical material Ji Yuan: be the rhizome of liliaceous plant Rhizoma Polygonati, Polygonatum cyrtonema Hua and P. kingianum.[nature and flavor] are sweet; Flat.[return through] spleen; Lung; Kidney channel.[function cures mainly] nourishing YIN and moistening the lung; Invigorating the spleen and replenishing QI, Zishen fill fine.Main deficiency of YIN chronic cough; Xeropulmonary cough; Insufficiency of the spleen weak; Lack of appetite xerostomia; Quench one's thirst; Deficiency of the kidney soreness of the waist and knees; Impotence and seminal emission; Tinnitus order is dark; Early whitening of beard and hair; Body void is won thin; Wind favus disease.
radix Adenophorae (Radix Glehniae) [source] is campanulaceae Lady bell plant four leaf Radix Adenophorae (Radix Glehniae) or its congener, is used as medicine with root.[nature and flavor] are sweet, cool.[function cures mainly] clearing away heat and nourishing YIN, nourishing the lung to arrest cough.Cure mainly tracheitis, pertussis, cough due to lung-heat, cough up phlegm yellow thick.
radix Ophiopogonis [source] this product is the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf).[nature and flavor] are sweet, and micro-hardship, is slightly cold.[return through] GUIXIN, lung, stomach warp.[function cures mainly] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
the dry mature fruit of Fructus Lycii [source] plant of Solanaceae lycium barbarum.[nature and flavor] are sweet, flat.[return through] returns liver, kidney channel.[function cures mainly] nourishing the liver and kidney, replenishing vital essence to improve eyesight.
the Radix Paeoniae Alba [source] this product is the dry root of ranunculaceae plant Radix Paeoniae.[nature and flavor] are bitter, sour, are slightly cold.[return through] returns liver, spleen channel.The pain relieving of [function cures mainly] suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
breaking cellular wall Pollen Pini [source] medical material Ji Yuan: Pollen Pini is the spermatid of pinaster pistil, having another name called pine yellow, is pure, the dry pollen that pick up from China indigenous tree pinaceae plant Pinus massoniana Lamb.[function cures mainly], containing the whole active nutritional compositions needed for life entity, comprising multiple proteins, aminoacid, mineral, enzyme and coenzyme, nucleic acid, monosaccharide, polysaccharide etc., total content reaches more than 200 and plants.Also nearly hundred kinds of enzymes, biotin, nucleic acid, cellulose, unsaturated fatty acid, Flavonoid substances, rutin isoreactivity materials are contained in addition in Pollen Pini.
the present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention for treatment bronchial asthma of child cure rate high and safe without toxic side effect, and can related complication be prevented.When compatibility is applied, owing to there is interactional relation between medicine and medicine, so some medicine promotes curative effect because of synergism, but also some medicine but may resist mutually and offset, weakens original effect; Some medicine alleviates because of mutual adapted or eliminates toxicity or side effect, but also some medicine makes effect of declines or unfavorable human body etc. because of interacting on the contrary, it is namely so-called single file, mutual reinforcement between, the mutual-assistance, mutual restraint between two drugs, the mutual-detoxication, the mutual inhibition, contrary.The compound recipe composition of the traditional Chinese medical science is a kind of type of organization playing Chinese Herbs, and its superiority is exquisite monarch, four natures and five flavors of drug lifting, by organic cooperation of medicine, reaches the curative effect improving medicine, and weakens the object of its adverse side effect.For the present invention, the combination of listed medical material, neither simply pile up between medical material, neither the addition of similar drug effect, but have certain combination principle, between formula medical material, compatibility is rigorous, the synergistic function produced after not only making full use of compatibility of drugs, and avoid pharmaceutically-active mutual Hangzhoupro short of money and offset or slacken original effect, more note selecting the compatibility of drugs application that can alleviate or eliminate the strong of medicine or toxic and side effects, firmly avoid the mutual compatibility of medicine and produce toxic reaction or strong side effect.In the present invention with Discolia Vittifrons Sch. room, Scorpio, Scolopendra altogether for monarch drug, with reach merit poison eliminating stagnation, cough-relieving flush end effect, make every effort to overcome asthma in acute attack.The Radix Astragali, Radix Codonopsis, Rhizoma Phragmitis, Herba Ephedrae, Radix Glycyrrhizae etc. are ministerial drug altogether, using medicines of both cold and hot natures simultaneously to reach benefiting QI for strengthening the superficies, lung qi dispersing Dingchuan.Help with Six-element conditioning the five internal organs such as Rhizoma Polygonati, Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, the Radix Paeoniae Alba, Fructus Lycii, wild Semen Canavaliaes, wherein Rhizoma Polygonati is sweet flat, spleen reinforcing lung moistening, and supplementing QI for promoting the production of body fluid, takes into account spleen, stomach, lung three warp; Radix Adenophorae (Radix Glehniae) sweetness and bitterness is slightly cold, lung heat clearing nourishing the liver, both can drive heresy, again can yin nourishing liver nourishing; Radix Ophiopogonis is sweet cold, and tonifying the lung nourishes heart, Yin-nourishing and body fluid promoting; Fructus Lycii is sweet flat, nourishing the liver to improve visual acuity, kidney nourishing and replenishing vital essence; Radix Paeoniae Alba picric acid is slightly cold, easing the affected liver yin fluid astringing, regulating blood flow to alleviate pains; This Six-element takes spleen, lung, the heart, liver, kidney QI of five ZANG-organs the moon respectively into account, reduces concurrent syndrome.Separately with pathogenic heat, wart bag flower relieving cough and resolving phlegm that the loose sun of Herba Lophatheri is bright, share with primordial QI reinforcing antitussive with breaking cellular wall Pollen Pini, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.By scientific compatibility, not only complicated in the state of an illness, when fast changing, the present invention can not only effectively organize and implement reasonable treatment, and for prevent disease progress, in invade internal organs and also have good preventive effect, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
in order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
embodiment 1
take: Radix Astragali 20g, Radix Codonopsis 15g, Rhizoma Phragmitis l2g, Herba Ephedrae 8g, Radix Glycyrrhizae 6g, Discolia Vittifrons Sch. room 13g, Scorpio 4g, Scolopendra 3g, wart bag flower 7g, Herba Lophatheri 8g, Piper longum dish 5g, wild Semen Canavaliae 6g, Rhizoma Polygonati 8g, Radix Adenophorae (Radix Glehniae) 8g, Radix Ophiopogonis 6g, Fructus Lycii 8g, Radix Paeoniae Alba 6g, breaking cellular wall Pollen Pini 5g.
preparation method is: mix after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.
usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; Within 15 days, be 1 course for the treatment of, take 1-2 the course for the treatment of continuously.
clinical data:
1, case selection:
select the routine clinical observation of bronchial asthma of child patient 78 in my institute's diagnosis and treatment, clinical symptoms all meets bronchial asthma of child diagnosis and treatment standard.Patient is divided into treatment group and matched group two groups at random, treatment group 43 example, matched group 35 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; It within 15 days, is 1 course for the treatment of.
matched group adopts conventional western medicine Comprehensive Treatment, the symptomatic treatment such as comprise infection, antiinflammatory, spasmolytic are relievingd asthma, the course for the treatment of same treatment group.
2 courses for the treatment of are treated in continuous smelting, contrast two groups of curative effects.
3, efficacy determination:
" disease of tcm Standardization of diagnosis and curative effect " that criterion of therapeutical effect is issued with reference to State Administration of Traditional Chinese Medicine is worked out.
(1) be almost recovered: cough, asthma disappear, and body temperature is normal, and pulmonary rale disappears, conducting lung X-ray examination performance recovers normal, and routine blood test recovers normal.
(2) take a turn for the better: cough, asthma alleviate, and pulmonary rale reduces, conducting lung X-ray examination performance does not recover completely.
(3) do not heal: clinical symptoms is without improvement or increase the weight of on the contrary.
4, result:
select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, be almost recovered 27 examples, and take a turn for the better 15 examples, and do not heal 1 example, and be almost recovered rate 62.8%, total effective rate 97.7%.Improvement and the patient that is almost recovered are followed the tracks of and follows up a case by regular visits to 12 months, 2 example recurrences, relapse rate 4.7%.
be almost recovered in matched group 14 examples, and take a turn for the better 15 examples, and do not heal 6 examples, and be almost recovered rate 40.0%, total effective rate 82.8%.Improvement and the patient that is almost recovered are followed the tracks of and follows up a case by regular visits to 12 months, 27 example recurrences, relapse rate 93.1%.
above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.
Claims (1)
1. one kind is used for the treatment of the Chinese medicinal capsule of bronchial asthma of child, it is characterized in that, be prepared from by the Chinese crude drug of following weight proportion: the Radix Astragali 20 parts, Radix Codonopsis 15 parts, Rhizoma Phragmitis l2 part, 8 parts, Herba Ephedrae, 6 parts, Radix Glycyrrhizae, 13 parts, Discolia Vittifrons Sch. room, Scorpio 4 parts, Scolopendra 3 parts, wart bag spend 7 parts, Herba Lophatheri 8 parts, Piper longum dish 5 parts, wild Semen Canavaliae 6 parts, Rhizoma Polygonati 8 parts, Radix Adenophorae (Radix Glehniae) 8 parts, Radix Ophiopogonis 6 parts, Fructus Lycii 8 parts, the Radix Paeoniae Alba 6 parts, breaking cellular wall Pollen Pini 5 parts.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105362864A (en) * | 2015-11-26 | 2016-03-02 | 李小群 | Pediatric bronchial asthma treatment pharmaceutical composition containing radix scutellariae |
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| JPH04275227A (en) * | 1991-01-11 | 1992-09-30 | Kazuhiko Ishii | Hemorrhoid therapeutic agent |
| CN102846846A (en) * | 2012-09-14 | 2013-01-02 | 山东福胶集团有限公司 | Donkey-hide gelatin paste and preparation method thereof |
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2015
- 2015-06-30 CN CN201510371917.7A patent/CN104984114A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04275227A (en) * | 1991-01-11 | 1992-09-30 | Kazuhiko Ishii | Hemorrhoid therapeutic agent |
| CN102846846A (en) * | 2012-09-14 | 2013-01-02 | 山东福胶集团有限公司 | Donkey-hide gelatin paste and preparation method thereof |
Non-Patent Citations (2)
| Title |
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| 北京中医医院儿科: "《中医儿科常见病证治概述》", 30 June 1984, 人民卫生出版社 * |
| 畅洪昇: "《吴鞠通传世名方》", 28 February 2013, 中国医药科技出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105362864A (en) * | 2015-11-26 | 2016-03-02 | 李小群 | Pediatric bronchial asthma treatment pharmaceutical composition containing radix scutellariae |
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