CN105030907A - Traditional Chinese medicinal capsules for treating chronic bronchitis - Google Patents

Traditional Chinese medicinal capsules for treating chronic bronchitis Download PDF

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CN105030907A
CN105030907A CN201510372060.0A CN201510372060A CN105030907A CN 105030907 A CN105030907 A CN 105030907A CN 201510372060 A CN201510372060 A CN 201510372060A CN 105030907 A CN105030907 A CN 105030907A
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chinese medicinal
chronic bronchitis
radix
traditional chinese
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丁奇
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Abstract

The invention discloses traditional Chinese medicinal capsules for treating chronic bronchitis. The traditional Chinese medicinal capsules are prepared from the following Chinese medicinal materials in parts by weight: 20 parts of radix astragali, 12 parts of codonopsis pilosula, 12 parts of rhizoma atractylodis macrocephalae, 10 parts of Anacyclus pyrethrum roots, 12 parts of thorny elaeagnus leaves, 12 parts of salvia miltiorrhiza, 10 parts of nidus vespae, 8 parts of gossypium herbaceum, 12 parts of milk skin, 8 parts of allyl amyl glycolate, 20 parts of prepared licorice, 8 parts of Yunnan wild angelica, 10 parts of rhus coriaria fruits, 12 parts of holly leaves, 6 parts of aizoon stonecrop herb, 8 parts of pine pollen disruption powder, 4 parts of spondias pinnata, 4 parts of ziziphus mauritiana, 5 parts of diospyros kaki silvestris and 4 parts of morus nigra. A clinical experiment shows that the remarkable effect of treating chronic bronchitis can be achieved by selecting proper medicinal materials and a proper proportion and the traditional Chinese medicinal capsules are safe and free of toxic or side effects.

Description

A kind of Chinese medicinal capsule being used for the treatment of chronic bronchitis
Technical field
the present invention relates to a kind of Chinese medicinal capsule, be specifically related to a kind of Chinese medicinal capsule being used for the treatment of chronic bronchitis.
Background technology
chronic bronchitis is that for common clinical, frequently-occurring disease are apt to occur in winter and spring, recurrent exerbation, touching difficulty more by infecting or the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucosa that non-infective agent causes and surrounding tissue.For this reason, the catabasis takes measures to alleviate or stop the generation of disease development significant.Treatment for chronic bronchitis still lacks the effective medicine of generally recognized as safe at present.
Summary of the invention
the present invention aims to provide a kind of Chinese medicinal capsule being used for the treatment of chronic bronchitis and preparation method thereof, by selecting suitable medical material and proportioning thereof, reaches the remarkable efficacy contributing to treating chronic bronchitis, and safe without toxic side effect.
in order to achieve the above object, the present invention is by the following technical solutions:
be used for the treatment of a Chinese medicinal capsule for chronic bronchitis, be prepared from by the Chinese crude drug of following weight proportion: the Radix Astragali 20 parts, Radix Codonopsis 12 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, dry root of Anacyclus pyrethrum(L.)DC. 10 parts, Folium Elaeagni 12 parts, Radix Salviae Miltiorrhizae 12 parts, 10 parts, Discolia Vittifrons Sch. room, cotton 8 parts, skin on boiled milk 12 parts, 8 parts, Ferula galbaniflua Boiss et Buhse fat, Radix Glycyrrhizae Preparata 20 parts, the wild Radix Angelicae Sinensis 8 parts in Yunnan, tan tree fruit 10 parts, Folium Ilicis Purpureae 12 parts, Herba Sedi Aizoon 6 parts, breaking cellular wall Pollen Pini 8 parts, Jamaica plum 4 parts, indian jujube 4 parts, wild Fructus Kaki 5 parts, 4 parts, black Mulberry.
preparation method is: mix after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.
the pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
radix Codonopsis [source] this product is the dry root of Campanulaceae Radix Codonopsis.[nature and flavor] are sweet, flat.[return through] returns spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
the Rhizoma Atractylodis Macrocephalae [source] this product is the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.[nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
the blade that Folium Elaeagni [source] is Elaeangnaceae plant Fructus Elaeagni.[nature and flavor] acid, flat, nontoxic.[function cures mainly] controls cough and asthma, hemoptysis, carbuncle, traumatic hemorrhage.[other]
radix Salviae Miltiorrhizae [source] this product is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae.[nature and flavor] are bitter, are slightly cold.[return through] GUIXIN, Liver Channel.[function cures mainly] stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
discolia Vittifrons Sch. room [source] is the nest of the red stricture of vagina Discolia Vittifrons Sch. of Scoliidae animal.[nature and flavor] mildly bitter flavor, warm in nature.[function cures mainly] Qinghuo Jiedu.To dispel the wind detumescence, stimulating milk secretion, cough-relieving flush end, leukorrhagia stopping.Cure mainly furuncle carbuncle furuncle abscess, innominate toxic swelling, skin erythema pruritus, galactostasis, cough, asthma, profuse leukorrhea.
the root that cotton [source] is Malvaceae plant cotton and seed.[nature and flavor] bitter in the mouth is sweet, micro-puckery, cool in nature.[function cures mainly] Qinghuo Jiedu, diuresis and expelling stone, relieving cough and asthma, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.Cure mainly the puckery pain of urine heat, lithangiuria, asthma, traumatic injury.
the processed goods of skin on boiled milk [source] Babalus bubalis L. or cattle milk surface oils and fats.[nature and flavor] are damp and hot, sweet in the mouth.[function cures mainly] raw humidogene heat, nourishing the lung to arrest cough, mend the fertile body of body, wet one's whistle sore throat relieving, mends stomach intestine moistening, anticorrosion wound healing, dispelling wind for relieving itching.Cure mainly dry cold or black gallbladder matter disease, as dryness of the lung dry cough, the empty body of body is thin, dry pharynx hoarseness, cold insufficiency of stomach, dryness of the intestine constipation, various skin trauma, psoriasis, tinea capitis.
ferula galbaniflua Boiss et Buhse fat [source] is the emulsive adhesive fat of samphire Ferula galbaniflua Boiss et Buhse Resina Ferulae.[nature and flavor] xeothermic micro-hardship.[function cures mainly] blood stasis dispelling wound healing, logical prevention pain, parasite killing pain relieving, except insane controlling nocturnal emission with astringent drugs, improving eyesight is humidified, inflammation-diminishing and cough-controlling, softening internal organs.Increase menses, bring down a fever and bring down a fever, removing toxic substances etc.; Control traumatic injury, sciatica, dental caries pain, juvenile seminal emission, eyesight weaken, chest pain is coughed, spleen enlargement.Uterosclerosis, hypomenorrhea, heating is trembled, and mad dog is bitten, and poisonous insect stings wound etc.
radix Glycyrrhizae Preparata [source] this product is the Preparation process product of Radix Glycyrrhizae.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] spleen reinforcing stomach function regulating, Yiqi and vein recovery.For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.
the almost ripe fruit that tree fruit [source] of tanning is set for Anacardiaceae vegetable tanning.It is dry cold that secondary is planted by [nature and flavor] family, does cold for wild three grades; Sour in the mouth.[function cures mainly] is raw dry raw cold, and dampness removing and diarrhea-relieving, tremble with fear and mend gastral cavilty, heat clearing away sending down the abnormal ascending QI, cooling blood for hemostasis, Gu tooth pain relieving, reducing urination quenches the thirst.Cure mainly humid or blood matter disease, as humid diarrhoea, dysentery, feels sick, vomiting, and heat in blood is hemorrhage, dental pain, moist polyuria, hot thirsty etc.
herba Sedi Aizoon [source] medical material Ji Yuan: be root or the herb of crassulaceae plants Herba sedi kamtschatici, horizontal root Herba sedi kamtschatici.[nature and flavor] put down; Sweet; Micro-acid.[return through] heart; Liver; Spleen channel.[function cures mainly] dissipating blood stasis; Hemostasis; Mind tranquilizing and the heart calming; Removing toxic substances.Main haematemesis; Epistaxis; Have blood in stool; Hematuria; Metrorrhagia; Purpura; Traumatic hemorrhage; Traumatic injury; Cardiopalmus; Insomnia; Furuncle carbuncle; Burn and scald; Insect bite.
breaking cellular wall Pollen Pini [source] medical material Ji Yuan: Pollen Pini is the spermatid of pinaster pistil, having another name called pine yellow, is pure, the dry pollen that pick up from China indigenous tree pinaceae plant Pinus massoniana Lamb.[function cures mainly], containing the whole active nutritional compositions needed for life entity, comprising multiple proteins, aminoacid, mineral, enzyme and coenzyme, nucleic acid, monosaccharide, polysaccharide etc., total content reaches more than 200 and plants.Also nearly hundred kinds of enzymes, biotin, nucleic acid, cellulose, unsaturated fatty acid, Flavonoid substances, rutin isoreactivity materials are contained in addition in Pollen Pini.
the dry root of the Radix Astragali [source] leguminous plant Radix Astagali.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
the wild Radix Angelicae Sinensis in wild Radix Angelicae Sinensis [source] Umbelliferae archangel Yunnan, Yunnan, is used as medicine with root.Autumn and winter adopt root, clean and dry.[nature and flavor] are pungent, temperature.[function cures mainly] promoting blood flow to regulate menstruation, nourishing blood for moistening dryness, laxation.For menoxenia, dysmenorrhea, blood stasis amenorrhea, anemia, rheumatic arthritis, traumatic injury, dryness of the intestine constipation etc.
the root that dry root of Anacyclus pyrethrum(L.)DC. [source] is feverfew Rome Pyrethrum.Peppery and the numb tongue of [nature and flavor] acrid in the mouth.The strong muscle of [function cures mainly] cold relieving, opens retardance, removes excess in brain, warm-up tonifying YANG, and tonneau is through water, and controlling nocturnal emission with astringent drugs, wind-expelling pain-stopping, drying dampness to eliminate phlegm, nourishing is neural.Cure mainly raw property or open-minded liquid matter disease, as paralysis, facial paralysis, of flaccid muscles, paralysis, vibration, skin ulcer is sick, tongue weight, hyposexuality, and seminal fluid is not solid, and amenorrhea is not smooth, and headache toothache, excessive phlegm is coughed, neurasthenia.
the blade that Folium Ilicis Purpureae [source] is holly plant Ilicis Purpureae.[chemical analysis] leaf is containing two kinds of antipathogenic compositions, and one of them is protocatechuic acid, separately containing volatile oil, flavonoid.[nature and flavor] are pained, cold.[function cures mainly] controls scald, ulcer disunion of a specified duration, thromboangiitis obliterans, acute and chronic bronchitis, pneumonia, urinary tract infection, and bacillary dysentery, traumatic hemorrhage, freezes chilblain, chaps.
the fruit that Jamaica plum [source] is Anacardiaceae plant Jamaica plum and bark.[nature and flavor] sour in the mouth, puckery, gas delicate fragrance, cool in nature.[function cures mainly] tranquilizing mind, heat-clearing and toxic substances removing, relieving cough and resolving phlegm, reducing swelling and alleviating pain.Cure mainly nervous cardiopalmus, cough with asthma, pertussis, painful and swollen testis, tinea.
the bark of indian jujube [source] Rhamnaceae plant indian jujube and leaf.[nature and flavor] puckery, micro-hardship.Property is put down.[function cures mainly] Qinghuo Jiedu, reducing swelling and alleviating pain, killing parasites for relieving itching, holds back water antidiarrheal.Cure mainly burn due to hot liquid or fire, toothache, distending pain of the breast, furuncle carbuncle furuncle abscess, impetigo, skin erythema pruritus, pruritus vulvae, diarrhoea, red white dysentery, abdomen turns round pain, twinge.
the root that wild Fructus Kaki [source] is the wild Fructus Kaki of Ebenaceae plant, branch and leaf.[nature and flavor] bitter in the mouth, puckery, gas is fragrant.Cold in nature.[function cures mainly] nurses one's health four towers, mends native stomach invigorating, Qinghuo Jiedu.Cure mainly weak, anorexia, weak and sickly, drought declines, jaundice, burn due to hot liquid or fire.
the black that black Mulberry [source] is the black Mulberry of moraceae plants or erythrocarpus.[nature and flavor] sour in the mouth is micro-sweet.[function cures mainly] dysregulation blood matter and bile matter, the pharyngolaryngitis that disappears swells, and stops hot body fluid to flee in upper respiratory tract, quenches the thirst and increases food, except infections heals skin ulcer, clearing away heat to stop diarrhea.Cure mainly hot or blood matter and bile matter disease, as pharyngolaryngitis swells, thirsty poor appetite, oral ulcer, intestinal skin ulcer is hindered, hot diarrhoea and dysentery.
the present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention for treatment chronic bronchitis cure rate high and safe without toxic side effect, and can related complication be prevented.Monarch, four natures and five flavors of drug lifting is particular about between prescription Chinese crude drug of the present invention.For the present invention, the combination of listed medical material, neither simply pile up between medical material, neither the addition of similar drug effect, but have compatibility between the formula medical material of certain combination principle rigorous, the synergistic function produced after not only making full use of compatibility of drugs, and avoid pharmaceutically-active mutual Hangzhoupro short of money and offset or slacken original effect, more note selecting the compatibility of drugs application that can alleviate or eliminate the strong of medicine or toxic and side effects, firmly avoid the mutual compatibility of medicine and produce toxic reaction or strong side effect.In prescription of the present invention: the Radix Astragali is longer than spleen invigorating QI invigorating, lung benefiting consolidating superficial resistance; Radix Codonopsis helps Radix Astragali air making-up and spleen enlivening benefit to defend, its sweet in the mouth normal person lung and not dry, kind replenishing and restoring lung-QI, for the deficiency of the lung is breathed with cough key medicine; The Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae Preparata work in coordination with the Radix Astragali, Radix Codonopsis to strengthen tonifying the lung function of invigorating spleen, and help the Radix Astragali to strengthen the power of consolidating superficial resistance; Dry root of Anacyclus pyrethrum(L.)DC. expelling wind and cold; Radix Salviae Miltiorrhizae nourshing blood and promoting blood circulation blood stasis dispelling, makes unobstructed vessel, and ventilation improves; Discolia Vittifrons Sch. room, Ferula galbaniflua Boiss et Buhse fat relieving cough and asthma; Folium Elaeagni both can have been controlled and breathe heavily, again can QI invigorating, attacked benefit and held a concurrent post; Yunnan wild Radix Angelicae Sinensis, cotton blood circulation promoting and blood stasis dispelling; Tan and set fruit, Folium Ilicis Purpureae bactericidal antiphlogistic; Herba Sedi Aizoon is stopped blooding, and breaking cellular wall Pollen Pini strengthens immunity; Radix Glycyrrhizae Preparata QI invigorating; All medicines share adjustment lung, spleen, renal function, and rise cough-relieving, reduce phlegm, antiasthmatic effect, make chronic bronchitis patient recur reduce, symptom alleviates, and reaches both to take stopgap measures, the effect effected a permanent cure again.By scientific compatibility, not only complicated in the state of an illness, when fast changing, the present invention can not only effectively organize and implement reasonable treatment, and for prevent disease progress, in invade internal organs and also have good preventive effect, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
in order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
embodiment 1
take: Radix Astragali 20g, Radix Codonopsis 12g, Rhizoma Atractylodis Macrocephalae 12g, dry root of Anacyclus pyrethrum(L.)DC. 10g, Folium Elaeagni 12g, Radix Salviae Miltiorrhizae 12g, Discolia Vittifrons Sch. room 10g, cotton 8g, skin on boiled milk 12g, Ferula galbaniflua Boiss et Buhse fat 8g, Radix Glycyrrhizae Preparata 20g, the wild Radix Angelicae Sinensis 8g in Yunnan, tan tree fruit 10g, Folium Ilicis Purpureae 12g, Herba Sedi Aizoon 6g, breaking cellular wall Pollen Pini 8g, Jamaica plum 4g, indian jujube 4g, wild Fructus Kaki 5g, black Mulberry 4g.
preparation method is: mix after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.
usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; Within 30 days, be 1 course for the treatment of, take 3 courses for the treatment of continuously.
clinical data:
1, case selection:
selected the routine clinical observation of chronic bronchitis patient 78 in my institute's diagnosis and treatment since 2013, clinical symptoms all meets chronic bronchitis diagnosis and treatment standard.Patient is divided into treatment group and matched group two groups at random, treatment group 39 example, matched group 39 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; It within 30 days, is 1 course for the treatment of.
matched group adopts conventional western medicine Comprehensive Treatment, the course for the treatment of same treatment group.
3 courses for the treatment of are treated in continuous smelting, contrast two groups of curative effects.
3, efficacy determination:
(1) be almost recovered: coughing, coughing up phlegm or panting all disappears.
(2) take a turn for the better: middle 1-2 item of coughing, cough up phlegm or pant obviously alleviates, another 1 unchanged.
(3) do not heal: cough, cough up phlegm or pant without changing, or increase the weight of before comparatively treating.
4, result:
select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, be almost recovered 18 examples, and take a turn for the better 15 examples, and do not heal 6 examples, and be almost recovered rate 46.2%, total effective rate 84.6%.
be almost recovered in matched group 11 examples, and take a turn for the better 16 examples, and do not heal 12 examples, and be almost recovered rate 28.2%, total effective rate 69.2%.
above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.Relevant Chinese medicine also exists rectification of name, different name, calls and be commonly called as, and the concrete medical material referred to all can be known by existing open source literature and network, also can with the substitute in the medical material generation of close effect.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.

Claims (1)

1. one kind is used for the treatment of the Chinese medicinal capsule of chronic bronchitis, it is characterized in that, be prepared from by the Chinese crude drug of following weight proportion: the Radix Astragali 20 parts, Radix Codonopsis 12 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, dry root of Anacyclus pyrethrum(L.)DC. 10 parts, Folium Elaeagni 12 parts, Radix Salviae Miltiorrhizae 12 parts, 10 parts, Discolia Vittifrons Sch. room, cotton 8 parts, skin on boiled milk 12 parts, 8 parts, Ferula galbaniflua Boiss et Buhse fat, Radix Glycyrrhizae Preparata 20 parts, the wild Radix Angelicae Sinensis 8 parts in Yunnan, tan tree fruit 10 parts, Folium Ilicis Purpureae 12 parts, Herba Sedi Aizoon 6 parts, breaking cellular wall Pollen Pini 8 parts, Jamaica plum 4 parts, indian jujube 4 parts, wild Fructus Kaki 5 parts, 4 parts, black Mulberry.
CN201510372060.0A 2015-06-30 2015-06-30 Traditional Chinese medicinal capsules for treating chronic bronchitis Pending CN105030907A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1165026A (en) * 1997-03-19 1997-11-19 李刚 Chinese drugs for treatment of chronic broncheitis and asthma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1165026A (en) * 1997-03-19 1997-11-19 李刚 Chinese drugs for treatment of chronic broncheitis and asthma

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
吴中朝: "《500种中药速认图鉴》", 31 January 2014, 江苏科学技术出版社 *
张问渠等: "《老年病中医治疗学》", 31 August 2000, 科学技术文献出版社 *

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