CN104983850A - Traditional Chinese medicinal ointment for treating chronic ulcer of skin - Google Patents
Traditional Chinese medicinal ointment for treating chronic ulcer of skin Download PDFInfo
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- CN104983850A CN104983850A CN201510372250.2A CN201510372250A CN104983850A CN 104983850 A CN104983850 A CN 104983850A CN 201510372250 A CN201510372250 A CN 201510372250A CN 104983850 A CN104983850 A CN 104983850A
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Abstract
The invention discloses a traditional Chinese medicinal ointment for treating chronic ulcer of skin. The traditional Chinese medicinal ointment is prepared from the following traditional Chinese medicinal materials in weight proportion: 15 parts of angelica sinensis, 15 parts of ligusticum wallichii, 15 parts of peach kernels, 9 parts of trona, 15 parts of morinda angustifolia, 30 parts of membranous milkvetch root, 15 parts of glue fat of ferula galbaniflua boissier, 9 parts of purpleflower holly leaves, 5 parts of sapium baccatum, 5 parts of Tibeten incarvillea sinensis, 12 parts of aizoon stonecrop herb, 6 parts of mutton tallow, 6 parts of liquoric root and 6 parts of pine pollen disruption powder. Clinical experiment results prove that through selecting the proper traditional Chinese medicinal materials according to the ratio, the ointment achieves the remarkable efficacy for treating chronic ulcer of skin, and is safe and free of toxic and side effect.
Description
Technical field
the present invention relates to a kind of Chinese medicinal ointment, be specifically related to a kind of Chinese medicinal ointment being used for the treatment of chronic skin ulcer.
Background technology
skin ulcer is the local organization defect that a variety of causes causes.More than the 2 weeks non-healing persons of wound surface are chronic skin ulcer.Chronic skin ulcer belongs to the categories such as " obstinate pyogenic sore of the skin ", " bed-sore " of the traditional Chinese medical science, comprises ulcer etc. on vascular ulcers (arterial occlusion hardening ulcer, varicose ulcer), traumatic ulcer, infective ulcer, chemical ulcer, radiation ulcer, pressure ulcer, neuratrophia ulcer, diabetic ulcer, venom ulcer, postburn hypertrophic scar.Treatment for chronic skin ulcer still lacks the effective medicine of generally recognized as safe at present.
Summary of the invention
the present invention aims to provide a kind of Chinese medicinal ointment being used for the treatment of chronic skin ulcer and preparation method thereof, by selecting suitable medical material and proportioning thereof, reaches the remarkable efficacy contributing to treating chronic skin ulcer, and safe without toxic side effect.
in order to achieve the above object, the present invention is by the following technical solutions:
be used for the treatment of a Chinese medicinal ointment for chronic skin ulcer, be prepared from by the Chinese crude drug of following weight proportion: Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 15 parts, 15 parts, Semen Persicae, Tronae 9 parts, Backhousia angustifolia halberd 15 parts, Radix Astragali 30 parts, 15 parts, Ferula galbaniflua Boiss et Buhse fat, Folium Ilicis Purpureae 9 parts, Sapium baccatum Roxb 5 parts, Tibet Herba Incarvilleae sinensis 5 parts, Herba Sedi Aizoon 12 parts, Adeps caprae seu ovis 6 parts, Herba Pyrolae 15 parts, Radix Glycyrrhizae 6 parts, breaking cellular wall Pollen Pini 6 parts.
preparation method is: all the other Chinese crude drugs except Adeps caprae seu ovis, Ferula galbaniflua Boiss et Buhse fat, Tronae and breaking cellular wall Pollen Pini are put into container by (1), add the distilled water of 8 ~ 10 times amount, soaks after 5 ~ 6 hours, boils 3 ~ 4 hours, extracts; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) get a little Oleum Sesami and be heated into liquid, slowly add Adeps caprae seu ovis, Ferula galbaniflua Boiss et Buhse fat, Tronae and breaking cellular wall Pollen Pini, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make thick unguentum.
the pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
the dry root of Radix Angelicae Sinensis [source] umbelliferae angelica.[nature and flavor] sweet, acrid, warm.[return through] returns liver, the heart, spleen channel.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
the dry rhizome of Rhizoma Chuanxiong [source] samphire Rhizoma Chuanxiong.[nature and flavor] are pungent, temperature.[return through] returns liver, gallbladder, pericardium channel.[function cures mainly] blood-activating and qi-promoting, wind-expelling pain-stopping.
semen Persicae [source] this product is the dry mature seed of rosaceous plant Fructus Persicae.[nature and flavor] bitter, sweet, flat.[return through] GUIXIN, liver, large intestine channel.[function cures mainly] blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.
tronae [source] is boil containing the alkaline earth of sodium carbonate to form or at salt water lakeside Nature creating.[nature and flavor] salty in the mouth, twenty, bitter, property is put down.[function cures mainly] to be dispelled Ba Dagan, is helped digestion, relieving constipation, only rotten, removing toxic substances.Cure mainly dyspepsia, stomach Ba Da does disease, constipation, women's mass formed by blood stasis, amenorrhea, placenta retention, skin infection.
the root bark that Backhousia angustifolia halberd [source] is Maguireothamnus speciosus Backhousia angustifolia halberd and leaf.[nature and flavor] bitter in the mouth, cool in nature.[function cures mainly] Qinghuo Jiedu, promoting the function of the gallbladder to alleviate jaundice, killing parasites for relieving itching, expelling pus and promoting granulation.Cure mainly jaundice, cholelithiasis, furuncle carbuncle furuncle abscess, skin pruritus, macule.Scabies, eczema, Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) is irritated, and children's's skin infection does not close up for a long time.
the dry root of Radix Astragali [source] leguminous plant Radix Astagali.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
ferula galbaniflua Boiss et Buhse fat [source] is the emulsive adhesive fat of samphire Ferula galbaniflua Boiss et Buhse Resina Ferulae.[nature and flavor] xeothermic micro-hardship.[function cures mainly] blood stasis dispelling wound healing, logical prevention pain, parasite killing pain relieving, except insane controlling nocturnal emission with astringent drugs, improving eyesight is humidified, inflammation-diminishing and cough-controlling, softening internal organs.Increase menses, bring down a fever and bring down a fever, removing toxic substances etc.; Control traumatic injury, sciatica, dental caries pain, juvenile seminal emission, eyesight weaken, chest pain is coughed, spleen enlargement.Uterosclerosis, hypomenorrhea, heating is trembled, and mad dog is bitten, and poisonous insect stings wound etc.
the blade that Folium Ilicis Purpureae [source] is holly plant Ilicis Purpureae.[chemical analysis] leaf is containing two kinds of antipathogenic compositions, and one of them is protocatechuic acid, separately containing volatile oil, flavonoid.[nature and flavor] are pained, cold.[function cures mainly] controls scald, ulcer disunion of a specified duration, thromboangiitis obliterans, acute and chronic bronchitis, pneumonia, urinary tract infection, and bacillary dysentery, traumatic hemorrhage, freezes chilblain, chaps.
the root that Sapium baccatum Roxb [source] is euphorbia plant Sapium baccatum Roxb.[nature and flavor] taste is micro-puckery, and property is put down.[function cures mainly] adjusts benefit four tower, and regulating menstruation and activating blood, mends native stomach invigorating, promoting the circulation of QI to relieve pain.How sick, weak cure mainly and have a delicate constitution, menstruation point is adjusted, dysmenorrhea, amenorrhea, abdominal distention, anorexia.
tibet Herba Incarvilleae sinensis [source] medical material Ji Yuan: for Bignoniaceae plant hides root and the seed of POLO flower.[nature and flavor] sweet in the mouth; Light; Warm in nature.[function cures mainly] benefiting QI and nourishing blood.Main prolonged illness is weak; Puerperal, breast was few; Dizzy; Anemia.
herba Sedi Aizoon [source] medical material Ji Yuan: be root or the herb of crassulaceae plants Herba sedi kamtschatici, horizontal root Herba sedi kamtschatici.[nature and flavor] put down; Sweet; Micro-acid.[return through] heart; Liver; Spleen channel.[function cures mainly] dissipating blood stasis; Hemostasis; Mind tranquilizing and the heart calming; Removing toxic substances.Main haematemesis; Epistaxis; Have blood in stool; Hematuria; Metrorrhagia; Purpura; Traumatic hemorrhage; Traumatic injury; Cardiopalmus; Insomnia; Furuncle carbuncle; Burn and scald; Insect bite.
the fatty oil that Adeps caprae seu ovis [source] is bovid goat or sheep.[nature and flavor] sweet in the mouth; [return through] warm in nature heart; Spleen; Kidney channel.[function cures mainly] tonify deficiency; Moisturize; Dispel the wind; Removing toxic substances.Main asthenia is won thin; Chronic dysentery; Dry mouth and constipation; Skin chap wrinkles; Flaccidity syndrome and arthralgia syndrome; Red red toxic swelling; Skin ulcer tinea skin infection; Burn and scald; Cold injury.
herba Pyrolae [source] medical material Ji Yuan: be the herb of Pyrolaceae plant traditional embankment, Herba pyrolae japonicae, pyrola japonicaKlenze ex Alef, Herba Pyrolae incarnatae.[nature and flavor] are sweet; Bitter; Warm in nature.[return through] liver; Kidney channel.[function cures mainly] the kidney invigorating bone strengthening; Expelling wind and removing dampness; Cough-relieving; Hemostasis.Main lumbago due to renal deficiency; Rheumatic arthralgia; Muscles and bones flaccidity is soft; New chronic cough is coughed; Spit blood; Epistaxis; Metrorrhagia; Traumatic hemorrhage.
radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
breaking cellular wall Pollen Pini [source] medical material Ji Yuan: Pollen Pini is the spermatid of pinaster pistil, having another name called pine yellow, is pure, the dry pollen that pick up from China indigenous tree pinaceae plant Pinus massoniana Lamb.[function cures mainly], containing the whole active nutritional compositions needed for life entity, comprising multiple proteins, aminoacid, mineral, enzyme and coenzyme, nucleic acid, monosaccharide, polysaccharide etc., total content reaches more than 200 and plants.Also nearly hundred kinds of enzymes, biotin, nucleic acid, cellulose, unsaturated fatty acid, Flavonoid substances, rutin isoreactivity materials are contained in addition in Pollen Pini.
the present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention for treatment chronic skin ulcer cure rate high and safe without toxic side effect, and can related complication be prevented.Monarch, four natures and five flavors of drug lifting is particular about between prescription Chinese crude drug of the present invention.For the present invention, the combination of listed medical material, neither simply pile up between medical material, neither the addition of similar drug effect, but have compatibility between the formula medical material of certain combination principle rigorous, the synergistic function produced after not only making full use of compatibility of drugs, and avoid pharmaceutically-active mutual Hangzhoupro short of money and offset or slacken original effect, more note selecting the compatibility of drugs application that can alleviate or eliminate the strong of medicine or toxic and side effects, firmly avoid the mutual compatibility of medicine and produce toxic reaction or strong side effect.The putrefaction removing of invigorating blood circulation such as Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Persicae in side, the invigorating the spleen and benefiting QI tonify deficiency such as the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Adeps caprae seu ovis, Herba Pyrolae, reuses the Radix Astragali, especially because of effect of its tool benefiting qi and raising yang, promoting pus discharge and tissue regeneration strengthening, the routed carbuncle and ulcer of kind holder, the unobstructed blood vessels of energy, popular meridians, have better facilitation to the wound surface do not closed up for a long time, help with Sapium baccatum Roxb regulating menstruation and activating blood again, Tibet Herba Incarvilleae sinensis benefiting QI and nourishing blood, Herba Sedi Aizoon mind tranquilizing and the heart calming, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.By scientific compatibility, not only complicated in the state of an illness, when fast changing, the present invention can not only effectively organize and implement reasonable treatment, and for prevent disease progress, in invade internal organs and also have good preventive effect, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
in order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
embodiment 1
take: Radix Angelicae Sinensis 15 grams, Rhizoma Chuanxiong 15 grams, 15 grams, Semen Persicae, Tronae 9 grams, Backhousia angustifolia halberd 15 grams, Radix Astragali 30 grams, 15 grams, Ferula galbaniflua Boiss et Buhse fat, Folium Ilicis Purpureae 9 grams, Sapium baccatum Roxb 5 grams, Tibet Herba Incarvilleae sinensis 5 grams, Herba Sedi Aizoon 12 grams, Adeps caprae seu ovis 6 grams, Herba Pyrolae 15 grams, Radix Glycyrrhizae 6 grams, breaking cellular wall Pollen Pini 6 grams; Preparation method is: all the other Chinese crude drugs except Adeps caprae seu ovis, Ferula galbaniflua Boiss et Buhse fat, Tronae and breaking cellular wall Pollen Pini are put into container by (1), add the distilled water of 8 ~ 10 times amount, soaks after 5 ~ 6 hours, boils 3 ~ 4 hours, extracts; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) get a little Oleum Sesami and be heated into liquid, slowly add Adeps caprae seu ovis, Ferula galbaniflua Boiss et Buhse fat, Tronae and breaking cellular wall Pollen Pini, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make thick unguentum.
usage and dosage: be evenly coated with by made ointment and touch affected part, notes avoiding ulceration place, and ointment covers the red and swollen all sites of pathological changes, and operation wants soft, prevents from damaging diseased region again, and after natural drying, knit dressing parcel with cotton, the front clear water of medication washes quiet coating again; Within 15 days, be 1 course for the treatment of, use 1-2 the course for the treatment of continuously.
clinical data:
1, case selection:
selected the routine clinical observation of chronic skin ulcer patient 72 in my institute's diagnosis and treatment since 2013, clinical symptoms all meets chronic skin ulcer diagnosis and treatment standard.Patient is divided into treatment group and matched group two groups at random, treatment group 54 example, matched group 18 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
treatment group uses the Chinese medicinal ointment obtained by the embodiment of the present invention 1, uniform application affected part; It within 15 days, is 1 course for the treatment of.
matched group adopts conventional western medicine Comprehensive Treatment, the course for the treatment of same treatment group.
2 courses for the treatment of are treated in continuous smelting, contrast two groups of curative effects.
3, efficacy determination:
(1) be almost recovered: wound surface heals completely.
(2) take a turn for the better: wound surface is shown in that epithelial tissue is to central growth, skin injury reduces.
(3) do not heal: wound surface still has pus, skin injury is without reduction.
4, result:
select in the treatment group of the embodiment of the present invention 1 Chinese medicinal ointment, be almost recovered 41 examples, and take a turn for the better 9 examples, and do not heal 4 examples, and be almost recovered rate 75.9%, total effective rate 92.6%.
be almost recovered in matched group 8 examples, and take a turn for the better 4 examples, and do not heal 6 examples, and be almost recovered rate 44.4%, total effective rate 66.7%.
above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.
Claims (1)
1. one kind is used for the treatment of the Chinese medicinal ointment of chronic skin ulcer, it is characterized in that, be prepared from by the Chinese crude drug of following weight proportion: Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 15 parts, 15 parts, Semen Persicae, Tronae 9 parts, Backhousia angustifolia halberd 15 parts, Radix Astragali 30 parts, 15 parts, Ferula galbaniflua Boiss et Buhse fat, Folium Ilicis Purpureae 9 parts, Sapium baccatum Roxb 5 parts, Tibet Herba Incarvilleae sinensis 5 parts, Herba Sedi Aizoon 12 parts, Adeps caprae seu ovis 6 parts, Herba Pyrolae 15 parts, Radix Glycyrrhizae 6 parts, breaking cellular wall Pollen Pini 6 parts.
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| CN103961546A (en) * | 2014-05-15 | 2014-08-06 | 张睿 | External powder for treating skin ulcer |
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| CN103961546A (en) * | 2014-05-15 | 2014-08-06 | 张睿 | External powder for treating skin ulcer |
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| 湖南中医药研究所: "《简易中医疗法（试行本）》", 31 December 1965 * |
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Application publication date: 20151021 |