CN104069056A - Skin-soothing itching-relieving lotion - Google Patents
Skin-soothing itching-relieving lotion Download PDFInfo
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Abstract
The invention discloses a skin-soothing itching-relieving lotion, and belongs to the technical field of traditional Chinese medicinal cosmetic itching-relieving lotion production preparation. The lotion is prepared from cobra-mylabris traditional Chinese and western medicinal materials, viper-natural plant water-soluble extract, snake oil-toad skin natural plant oil, zaocys dhumnade-pine needle natural plant, viper-snake gall-cypress essential oil and a snake slough-pig bile natural plant extract. The main components of the itching-relieving lotion comprises effective essential active components of a plurality snake meat, skin, bile, slough and natural plants, water and medical alcohol; the skin-soothing itching-relieving lotion has the effects of clearing heat and removing toxicity, diminishing swelling and eliminating stasis, sterilizing, inhibiting bacteria and removing viruses, blocking sunshine and ultraviolet ray, proofing mosquito and mite, relieving pain and itching, refreshing and tranquilizing, emitting fragrance to relieve summer-heat, eliminating fatigue, preventing sleepy, refreshing body and relieving summer-heat, and is fragrant and cool, and does not have toxic or side effect. The itching-relieving lotion is widely applicable to people at different ages and different genders all year round, is a skin-soothing itching-relieving lotion extracted from pure natural animals and plants for removing wrinkles and spots, eliminating acnes and whitening.
Description
Technical field:
The invention discloses a kind of Shu Er skin antipruritic water, is to belong to Chinese medicine cosmetic antipruritic water preparation production technical field.
Background technology:
Be accompanied by starting of the worldwide upsurge that goes back to nature, Cosmetic Market is developed rapidly to pure natural curative effect-type direction by synthesis type.Various countries release one after another medical herbs cosmetics, pure natural plant cosmetics and biological engineering cosmetic product, started development, used and promoted the another climax of natural cosmetics.China's history of TCM is long, and aboundresources.Modern study result shows: many Chinese herbal medicine and animal product have the definite function of preventing and treating dermatosis, strengthening skin-nourishing and preventing and treating ultraviolet radiation, for greasiness, be dried, chap, the skin abnormality phenomenon such as mottle, acne, wrinkle has obvious curative effect, can also promote the blood circulation of blood capillary in skin, hair simultaneously, improve the nutrition supply of skin, hair, strengthen skin elasticity, reduce Keratoderma and pigmentation, prevent skin, hair hypofunction, thereby reach the object of beauty treatment, slow down aging.Therefore Chinese medicine cosmetic has its unique effects, and its effect comprises that cleaning action, protective effect, Nutrition, beautification function, preventive and therapeutic effect etc. and skin trace element supplement, adjustment etc.
Chinese medicine is applied to cosmetics, meet the trend of world today's cosmetics development, if correctly developed, scientifically studied, produce a series of Chinese medicine cosmetics that have no side effect, integrate beauty and make-up and health therapy, will make Chinese medicine is that the mankind make larger contribution.
Summary of the invention:
The object of the present invention is to provide a kind of Shu Er skin antipruritic water.
The scheme that the technology of the present invention solves is:
A Shu Er skin antipruritic water, is characterized in that: by following quality proportioning, form %
(1) a Shu Er skin antipruritic water, is characterized in that: each quality of material proportioning of Naja Mylabris forms %
Compound method:
1. Agkistrodon is soaked in 95% medical alcohol to 15 days with standby by the full Serpentis of 10%-30%;
2. salicylic acid, benzoic acid are dissolved in the Radix Rumicis Japonici tincture that concentration is 10%-35%, after standing sealing 1-40h, add Mylabris, then to add concentration be the ethanol of 50%-75%, soak after 1-20d, filter and remove residue, by after filtrate ebuillition of heated distillation cooling condensation, adds distilled water and alcoholic solution, then with the abundant hybrid filtering of Naja ethanol liquid and by filtrate, alcohol concentration is adjusted to 70%-75% alcohol concentration, obtains yellow or flaxen limpid liquid medicine, be finished product.
This product can be used for treating facial acne, acne, tinea versicolor, the raw skin ulcer of the corners of the mouth, dispels eczema, beriberi, very itches and have specially good effect, and rhinitis is also had to good efficacy.
When treatment acne, acne, tinea versicolor, the raw skin ulcer of the corners of the mouth, this product is applied in to affected part.
Product attribute: this product formula forms few, and technique is simple, use, instant effect, effective, to skin non-corrosiveness, with after have no adverse reaction.
The Semen Ginkgo all wind of face of can decaptitating, Flos Chrysanthemi Indici can heat-clearing and toxic substances removing, and Radix Saposhnikoviae can expelling pathogenic wind from the body surface dehumidifying, and the Radix Angelicae Dahuricae can dispeiling pathogenic wind and removing dampness, detumescence and apocenosis.
(2) a Shu Er skin antipruritic water, is characterized in that: Agkistrodon halys natural plant water-soluble extract, forms % by following quality proportioning
A, Agkistrodon halys are organized natural plant water-soluble extract
B, compound skin-whitening speckle dispelling Shu Er skin antipruritic water
Preparation method:
1. Agkistrodon halys is organized the method for making of natural plant water-soluble extract
A, by Agkistrodon halys meat, Radix Ginseng, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Cortex Mori, Folium Vaccinii vitis-idaeae, Folium Pini, Radix Scutellariae by 1: (10-20) add deionized water, soak, decoct, filter, collect filtrate;
B, by filtering residue by 1: (10-20) add deionized water, soak, decoct, filter, collect filtrate;
C, by filtering residue by 1: (5-10) add 95% ethanol, soak, filter, collect filtrate;
D, by filtering residue repeating step c, collect filtrate;
E, a, b, c, d gained filtrate are merged;
2. the method for making of FUHE MEIBAI QUBAN YE
A, plant water-soluble extract, kojic acid, propylene glycol, hyaluronic acid, methyl hydroxybenzoate, propylparaben are added in deionized water successively, mixing limit, limit stirs;
B, in material a, add solubilizing agent, essence, stir;
C, by material b ultraviolet disinfection 30-40min, elimination insoluble matter, discharging, standing 24h, subpackage, gets product after the assay was approved;
Product application: this product is mainly used in dispelling freckle, chloasma, senile plaque and the melanin deposition etc. that cause because of Exposure to Sunlight, hormonal disorder, age increase, black eye, eye pouch, birthmark, wrinkle etc. are had to desalination effect, acne, acne, blackhead are also had to good effect, dermatitis, eczema, miliaria, itching skin disease are had to the miliaria itching-relieving action of well dispelling.
This product should, in 15-25 ℃ of sealed storage in the dry environment of darkness, avoid directly accepting sunlight or strong illumination.
Product attribute: this product technique is simple, and product quality is easily controlled, can be made into the series of products such as water preparation, spirits, cream frost, emulsion, essence, antipruritus toilet water, pure natural animal and plant medicine; Rationally, abnormal smells from the patient is slight for formula, and pH value is 4-6.5, is easy to absorb, and result of use is remarkable; Containing compositions such as hydroquinone, not without any side effects, safe and reliable.
(3) a Shu Er skin antipruritic water, is characterized in that: Adeps Serpentis Cutis Bufonis crude vegetal forms % by following quality proportioning
Compound method: first Cutis Bufonis, Rhizoma Paridis, each herbal medicine immersion of the Radix Angelicae Dahuricae, after two weeks, are got to its filtrate by top other drug blend, finally add 95% medical alcohol to 100% to stir; Then with distilled water, adjusting product alcohol concentration is 65%-75% left and right.
This product miliaria of dispelling is antipruritic, anti-inflammation and sterilization, and detumescence is except furuncle, refreshment, delicate fragrance expelling summer-heat, pure and fresh improving eyesight, the effects such as health care, especially applicable senile skin pruritus, scrotum, eczema, miliaria, little furuncle, seasick, carsick, driver relieve tiredness anti-drowsy.
(4) a Shu Er skin antipruritic water, is characterized in that: by Zaocys Folium Pini pure natural plant, by following quality proportioning, form %
Preparation method: by above-mentioned various Chinese medicine select respectively, clean, dry, co-grinding, immersion, filtration, after decolouring, refilter, sterilizing product.
This product is a kind of beauty treatment Shu Er skin antipruritic water, as looks improving and the skin nourishing, antipruritic, miliaria disappears.
This product has the effect of nourishing skin of face, conditioning skin nutrition and moisture, antiinflammatory comprehensively, antipruritic, skin whitening, especially to facial colour spot, dark and gloomy, withered and yellow, relax, be dried, do not have the symptoms such as elasticity and expression to have the peculiar effect of improving, and formula rationally, production method is simple, cost is low, have no side effect, pure natural.
(5) a Shu Er skin antipruritic water, is characterized in that: by Agkistrodon halys Fel Serpentis Cypress ethereal oil, by following quality proportioning, form %
Preparation method:
A, whole medicament mixed is added after evenly and in alcoholic solution, soak 20-90min;
B, medical material and alcohol mixeding liquid after soaking are carried out to Steam Heating extraction, extract 10-45min;
C, stop heating, until medical material and alcoholic solution cooling after, put into the standing 8-24h of refrigerator, make medical material and solution layering;
D, get the ethanol supernatant after stratification, obtain finished product;
Product application: this product is that a kind of beauty treatment and eliminating spot, wrinkle resistant, anti-demodicid mite can skin whitening, removes wrinkle.
Product attribute: the Biochemical Mechanism that this product forms for pigment, mottle, utilize the mutual synergism of the whitening and speckle dispelling active component of plurality of Chinese, effectively reduce and restrain the activity of TYR enzyme, effectively prevent melanic formation and transition deposition, simultaneously effectively decompose, reduce the melanin forming in skin, mottle is easily eliminated.
The preparation method of Fructus Luffae liquid is that the Ramulus Luffae stem portion in growth is cut off or opens an osculum, accesses the Fructus Luffae liquid of outflow with container.
In Fructus Luffae liquid, containing organized enzyme and the many kinds of substance useful to human body, can reduce the generation of skin Lao Pi, thereby remove wrinkle of skin, keep skin delicate; Boric acid can be removed Lao Pi, skin care; Lac regis apis can provide nutrition for skin; Glycerol can prevent xerosis cutis; Tasteless medical alcohol has sterilizing, prevents dermopathic effect.
(6) a Shu Er skin antipruritic water, is characterized in that: by Periostracum Serpentis Fel Sus domestica natural plants, by following quality proportioning, form %
Preparation method: weigh and prepare by said ratio, first use purified rinse water dedusting after mixing, after dress extraction pot, be soaked in water after 2-4h, heat to 100 ℃, boil and boil leaching medicinal liquid after 2h; And then add water and be warming up to 100 ℃, boil and carry leaching medicinal liquid after 2h,, all over mixing, reinstall and in concentration tank, carry out negative pressure the be concentrated into raw material amount of 1: 1 (mass ratio) with head, go out tank after medicinal liquid is cooling, add 3 times of 80% ethanol, stirring; After precipitate with ethanol 24h, leach the orange liquid of supernatant, supernatant is packed into and in concentration tank, receives wine and be concentrated into 50% of former concentrated solution, after sterilizing is processed, can fill use after cooling.
Fel Serpentis has the special effect of diminishing speckle and pox, and dispelling pathogenic wind and eliminating phlegm is treated infantile malnutrition parasite killing, clearing away heat to improve acuity of vision, and the miliaria of dispelling stops miliaria, and the equivalence of skin pyretic toxicity is used.
Folium Pini is in summer, and Folium Pini water treatment miliaria has special effect.On health, there are summer sweat or health not dry and comfortable, easily produce miliaria, unbearably scratchy.Cotton ball or gauze, with decocting well-done Folium Pini water-soaked, are spread upon to affected part, and miliaria will soon disappear.
Infant skin is tender and lovely, is coated with the elimination miliarias such as floral water, and child's skin is had to stimulation, with Folium Pini water, eliminates miliaria health safety again.
With Radix Ginseng, Herb Gynostemmae Pentaphylli extract, in order to reach, stop human skin aging and to senile cell is repaired object;
Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis have good nourish blood, invigorate blood circulation, the effect of defying age and elimination free radical (melanin);
Aloe, Radix Sophorae Flavescentis have stronger antiinflammatory moisturizing, killing parasites for relieving itching and anti-allergic effects;
Eight taste natural drugs combinations reach wrinkle removal, speckle dispelling jointly, except pox, brighten, the effect of skin care.
This product be a kind of pure natural plant extract wrinkle removal, speckle dispelling, except pox, brighten, skin-protecting face nursing Shu Er skin antipruritic water.
This product main component is the effective elite active component of water and natural plants.Due to ethanol extraction concentrated effect, the experiment proved that this product undergoes no deterioration in 1 year, variable color, so need not add again therein antiseptic, antibacterial and stabilizing agent.This product is nontoxic, without any side effects, is widely used in men and women, old and young's different crowd, dissimilar beautifying skin and maintenance the whole year, be a kind of pure natural plant extract the wrinkle removal that forms, speckle dispelling, except pox, brighten, skin care, beauty care Shu Er skin antipruritic water.
Agkistrodon halys is rich in the necessary various trace elements of human skin tissue, and Rhizoma Paridis has heat-clearing and toxic substances removing, detumescence dissipating blood stasis, the effect of resisting pathogenic microbes, the effect of prevention multiple dermatosis and co-treatment eczema, dermatitis, tinea.
The Radix Angelicae Dahuricae can be treated skin pruritus, tinea scabies, facial black speck, make skin pure white, it is glossy that flexible cosmetology is moistened, and have effect sun-proof, anti-ultraviolet, and it mixes with Mentholum, carbonic acid, salicylic acid etc. compositely has positive effect to the erubescence swell and itch of skin after mosquito bite.Radix Aucklandiae oil, Camphora, Oleum lavandula angustifolia, Radix Oenotherae erythrosepalae absolute oil have anti-inflammatory anti-itch, refreshment delicate fragrance expelling summer-heat, it is tired to eliminate, prevent sleepy health care effect, adding Borneolum Syntheticum Moschus, grass phenol, Fructus Citri Limoniae oil makes skin have more refrigerant sense, effect to delicate fragrance refreshment, the expelling summer-heat of refreshing oneself is stronger, thin up is also used as the perfume of delicate fragrance refreshment, the refreshing refrigerant floral water of body expelling summer-heat delicate fragrance.The Radix Paeoniae Alba coordinates the infectious acne of other Chinese medicine quality to have better therapeutic effect.
Periostracum Serpentis is again imperial clothing, Rhizoma aspidistrae luridae etc., and it is the body surface horny layer of Serpentis under life is wherein sloughed off naturally, contains the compositions such as ossein.All can pick up the whole year, dries standby after Ex-all silt.Its body is light, matter is crisp frangible, and abnormal smells from the patient is raw meat slightly.The person of being used as medicine take that bar is long, glossy, free from admixture person is as good.The Periostracum Serpentis of hyoscine, trembles clean silt and deposits after picking up.Periostracum Serpentis contains the compositions such as ossein, has the functions such as heat-clearing and toxic substances removing, wind dispelling insecticide, improving acuity of vision and removing nebula.Cure mainly the diseases such as convulsion with spasms, all pyogenic infections from tumour or sore, laryngopharynx swelling and pain, lumbago, breast swell and pain, anal fistula, scabies, cerebral cysticercosis, corneal nebula.With powder or decoct, use it.Without pathogenic wind toxic person and contraindication in pregnancy.
< < Compendium of Materia Medica > > carries Periostracum Serpentis: " ward off evil, remove wind parasite killing.Ashing clothes are controlled married woman's lactogenic, adult's acute throat trouble.Move back corneal nebula, swollen and rigid tongue disappears.Children's's Fu congenital deformity of the tongue, heavy palate lockjaw, infantile metopism, acne vulgaris, lunar eclipse, pemphigus; Adult's furuncle is swollen, anal fistula toxic swelling.Boil soup and wash all evil insect bites.”
Trace element in Agkistrodon halys body is measured through high-frequency inductive coupling plasma body spectrographic method (ACP-AES), finds that the skin of Agkistrodon halys contains the macroelements such as the various trace elements such as Zn, Cu, Mn, Fe, Ge, Co, Cr, Sr, Sn, As, Al, Mo, Ni, Cd, Li, Te and Pb and K, Na, Ca and Mg.They all have important effect at aspects such as the biosynthesis of living things catalysis, electronics transmission, mass transfer, nerve, body fluid adjusting, immunoreation, metabolism and nucleic acid, protein, enzyme, hormone and heredity, growths.The organ of human body maximum is skin, and skin participates in the metabolism of whole body.
The constituent contents such as zinc, copper, ferrum and skin relation are also comparatively close, and when epithelial cell is formed as zinc, the synthetic and fibrocellular hypertrophy of collagen is very important, if zinc contains quantity not sufficient, wound is difficult to healing; And for example copper is in keratin forming process, and the process that sulfydryl is changed into disulfide bond plays a part certain, and relevant with glycolysis, be again one of main component of melanin formation cheese ammonia enzyme, if lack copper, cutin forms bad, there is the complete and hair waving of keratinization of epidermis, make skin and hair decolouring; For another example selenium can affect keratinization of epidermis program, reduces coming off of horn cell.Also have ferrum to participate in the synthetic of hemoglobin, iron deficiency can cause spoon nail or onychorrhexis etc.If want the skin that unsoundness is beautiful, must maintain the balance of multiple element in body.This is the key point of beauty treatment.And being rich in the required various trace elements of human skin tissue, Agkistrodon halys tissue makes up the needs that skin histology element must reach people's in-vivo element balance.
In extract from pine needles, be rich in water-soluble bioflavonoids concentrate, this is a kind of antioxidant, contains catechin, phenols fruit acid and a large amount of oligomeric proanthocyanidins, wherein remove free radical ability the strongest be oligomeric proanthocyanidin.Oligomeric proanthocyanidin can also promote the generation of antioxidase in cell.The ferrum element containing in Folium Pini is the central atom of hemoglobin, is the ingredient of many enzymes, and iron deficiency can cause anemia and affect the normal growth of cell, cause alopecia, fear of cold; Child's iron deficiency, has the unconcentrated phenomenon of energy of attending class.The copper containing in Folium Pini plays certain activation in hemoglobin is synthetic, and copper shortage can cause osteoporosis, arthritis.Every kilogram, Folium Pini is containing 3.5 milligrams of coppers.In Folium Pini, selenium constituent content is high especially, and every kilogram containing 3.6 milligrams.Human body is few to the demand of selenium, but very important, and selenium is also consistent generally acknowledged Anticancer Element Selenium in the world, is described as " anticancer king ".Selenium is combined and can be maintained health of heart with vitamin E, and middle age selenium element lacks, meeting geromorphism, and there is in advance climacteric phenomenon in some meetings.If people's the dandruff is more, often also lack relevant with selenium element.World Health Organization (WHO) points out: take in for each person every day the selenium of 0.05-0.2 milligram, just can greatly reduce the sickness rate of cancer.Selenium element also has the specific function of the hypertoxic heavy metal elements such as antagonism hydrargyrum, cadmium, toxin expelling.In Radix Panacis Quinquefolii, Bulbus Allii, pluck, beef and mutton, also there is selenium element.Every kilogram, Folium Pini is containing 15 milligrams of zinc element.Zinc element is most important defying age element in human body, is the natural enemy of esophageal carcinoma.It participates in the activation of the synthetic and enzyme of 100 plurality of enzymes in human body, participates in the synthetic of nucleic acid and protein directly, thereby has delayed cell ageing process.Human body has had wound, and zinc element can participate in the healing of wound.The people that zinc element lacks, the sense of taste is numb, is not afraid of pungently, easily catches a cold.Zinc element can also prevent male infertility, and sexual function improving is removed people's pica and prevention child's dwarfism etc.Lacking that zinc element the most directly shows is that fingernail covers adularescent speckle, summer Folium Pini water stop that miliaria is antipruritic a special effect.
Fel Serpentis is in Serpentis body, to store the gallbladder of bile.General Fel Serpentis can be used as medicine, and take the Fel Serpentis of Naja, Bungarus fasciatus, Ptyas korros (above Fel Serpentis is collectively referred to as " three Fel Serpentis "), Agkistrodon, Ophiophagus hannan (Cantor), Zaocys, Elaphe taeniurus Cope, Serpentis, Agkistrodon, Elaphe radiata etc. as excellent.It can catch that wind dries, refrigerant improving eyesight, relieving cough and resolving phlegm.Be applied to clinically treat rheumatic arthritis, eye red order paste, cough ant phlegm, infantile convulsion, hemiplegia, hemorrhoid redness etc., all have good efficacy.Someone also eats Fel Serpentis and treats the diseases such as stomachache.By the viewpoint of the traditional Chinese medical science, say that three Fel Serpentis are searched the position of wind different, synergism can be received better curative effect: Ptyas korros gall can be searched the wind on top, and cobra gall can be searched the wind at middle part, and banded krait gall can be searched the wind of bottom.If three Fel Serpentis add the gallbladder of Agkistrodon, Serpentis again, form five Fel Serpentis, its effect is better.When controlling certain disease, the Fel Serpentis of some Special Categories also has specially good effect, as multibanded krait gall is controlled infantile convulsion.
With regard to chemical composition, Serpentis class to mammiferous bold cause similar.In bile, except containing bile acid, also have phospholipid, cholesterol and ester, bile pigments etc.In Serpentis, the physiological function of bile is to help fatty digestion, absorption and transportation.The color of Fel Serpentis, the kind that major part is used as medicine mostly is dark green.Indivedual kinds are as gallbladder of zaocys dhumnade, although also having under normal circumstances when raising orangely or light red, after raising, also just become bottle green.The color of Fel Serpentis is good mainly with dark green person greatly.General by yellowish or orange being called " water gallbladder ", be not conventionally used as medicine.
Natural Cypress ethereal oil has to avoid to acarid keeps away effect, is the jinx of acarid, and to the mankind and mammal totally nontoxic but can stop the growth and breeding of acarid.Human body exuviae every day bits, enough 1,000,000 acarids of fed to appetite.Acarid will be drained tens times every day, and Excreta is extremely dry, and each Excreta can split into several granules again, and they are extremely light, and floatability aloft.These molecules through decomposing, are walked about, make the bed, are folded quilt, housecleaner etc. by people, fly upward in air, especially by air-conditioning, spray, and this is all extremely strong anaphylactogen.After people's contact or suction of anaphylactogen body constitution, will induce an illness, show that respiratory tract is exactly allergic rhinitis, allergic asthma; Showing skin, is exactly dermatitis, and the acne that especially face mite causes, teenager.
One of effective ingredient that Chinese medicine Herba Andrographis and Western medicine salicylic acid are this product.Herba Andrographis has heat-clearing and toxic substances removing, antiinflammatory, takes off swollen effect, can be used for the treatment of various infection; Salicylic acid has the effect that sterilization is anticorrosion, Antifungi is grown, and can be used for treating for skin disease, and the salicylic acid of low concentration (2%-5%) has the effect that promotes epidermal growth for local hyperkeratosis.
This product has obvious In Vitro Bacteriostasis to staphylococcus glucose coccus, epidermis staphylococcus glucose coccus, D group streptococcus, propionibacterium, also has the effect that promotes epidermal growth, is mainly used in treating acne, acne.
This product technique is simple, and formula is reasonable, stable performance; Finished product is tincture, easy to use, and effect is remarkable, and effective percentage is more than 90%; Have no side effect and national reaction, safe and reliable.
Shu Er skin antipruritic water check conclusion:
1, the total number of bacterial colonies of Shu Er skin antipruritic water, coliform, staphylococcus aureus, bacillus pyocyaneus, Hemolytic streptococcus, fungus colony sum meet the requirement of the disposable use hygienic article of < < sanitary standard > > GB15979-2002.
2, according to the disposable use hygienic article of < < sanitary standard > > GB15979-2002, Shu Er skin antipruritic water is under experimental condition, before stability test, effect 2min is 99.9% to the average antibiotic rate of staphylococcus aureus; Effect 5min is 100.0% to the average antibiotic rate of staphylococcus aureus; Effect 10min is 100.0% to the average antibiotic rate of staphylococcus aureus; Effect 20min is 100.0% to the average antibiotic rate of staphylococcus aureus; Shu Er skin antipruritic water has antibacterial action.
3, according to the disposable use hygienic article of < < sanitary standard > > GB15979-2002, Shu Er skin antipruritic water is under experimental condition, before stability test, effect 2min is 99.9% to colibacillary average antibiotic rate; Effect 5min is 100.0% to colibacillary average antibiotic rate; Effect 10min is 100.0% to colibacillary average antibiotic rate; Effect 20min is 100.0% to colibacillary average antibiotic rate; Shu Er skin antipruritic water has antibacterial action.
4, according to the disposable use hygienic article of < < sanitary standard > > GB15979-2002, Shu Er skin antipruritic water is under experimental condition, 54 ℃, after 14 days, effect 2min is 99.9% to the average antibiotic rate of staphylococcus aureus; Effect 5min is 100.0% to the average antibiotic rate of staphylococcus aureus; Effect 10min is 100.0% to the average antibiotic rate of staphylococcus aureus; Effect 20min is 100.0% to the average antibiotic rate of staphylococcus aureus; Shu Er skin antipruritic water has antibacterial action.
Antibacterial tests before Shu Er skin antipruritic water stability test
One, equipment:
1, test strain: escherichia coli (8099), Jiangsu Prov. Disease Preventing and Controlling Center provides, the 4th generation
2, test specimen: Shu Er skin antipruritic water
3, phosphate buffer (PBS0.03mol/L, pH7.2)
4, culture medium: ordinary nutrient agar
5, main test instrument: PYX-DHS-50*65 water isolation type electro-heating standing-temperature cultivator, functional.
6, nertralizer: containing 0.3%Na
2s
2o
3+ 0.2% lecithin+0.3%Tween80PBS liquid.
Two, method:
1, detect foundation: the disposable use hygienic article of < < sanitary standard > > GB15979-2002
2, testing conditions: 15 ℃ of test temperatures, relative humidity 50%.
Three, result:
Stability test is front to colibacillary antibacterial effect
Note: test is respectively 5.0*10 by the total number of bacteria of (8099) three experiment contrast sheets of escherichia coli
4cfu/ sheet, 6.2*10
4cfu/ sheet, 7.8*10
4cfu/ sheet.
Four, conclusion
According to the disposable use hygienic article of < < sanitary standard > > GB15979-2002, Shu Er skin antipruritic water is under experimental condition, effect 2min is 99.9% to colibacillary average antibiotic rate before stability test; Effect 5min is 100.0% to colibacillary average antibiotic rate before stability test; Effect 10min is 100.0% to colibacillary average antibiotic rate before stability test; Effect 20min is 100.0% to the average antibiotic rate of test organisms before stability test; There is antibacterial action.
Antibacterial tests before Shu Er skin antipruritic water stability test
One, equipment:
1, test strain: staphylococcus aureus (ATCC6538), Jiangsu Prov. Disease Preventing and Controlling Center provides, the 4th generation
2, test specimen: Shu Er skin antipruritic water
3, phosphate buffer (PBS0.03mol/L, pH7.2)
4, culture medium: ordinary nutrient agar
5, main test instrument: PYX-DHS-50*65 water isolation type electro-heating standing-temperature cultivator, functional.
6, nertralizer: containing 0.3%Na
2s
2o
3+ 0.2% lecithin+0.3%Tween80PBS liquid.
Three, method:
1, detect foundation: the disposable use hygienic article of < < sanitary standard > > GB15979-2002
2, testing conditions: 15 ℃ of test temperatures, relative humidity 50%.
Four, result:
Antibacterial effect to staphylococcus aureus before stability test
Note: test is respectively 4.5*10 by the total number of bacteria of three experiment contrast sheets of staphylococcus aureus (ATCC6538)
4cfu/ sheet, 7.2*10
4cfu/ sheet, 6.2*10
4cfu/ sheet.
Five, conclusion
According to the disposable use hygienic article of < < sanitary standard > > GB15979-2002, Shu Er skin antipruritic water is under experimental condition, effect 2min is 99.9% to the average antibiotic rate of staphylococcus aureus before stability test; Effect 5min, before stability test, the right average antibiotic rate of staphylococcus aureus is 100.0%; Effect 10min is 100.0% to the average antibiotic rate of staphylococcus aureus before stability test; Effect 20min is 100.0% to the average antibiotic rate of staphylococcus aureus before stability test; There is antibacterial action.
Antibacterial tests after Shu Er skin antipruritic water stability test
One, equipment:
1, test strain: staphylococcus aureus (ATCC6538), Jiangsu Prov. Disease Preventing and Controlling Center provides, the 4th generation
2, test specimen: Shu Er skin antipruritic water
3, phosphate buffer (PBS0.03mol/L, pH7.2)
4, culture medium: ordinary nutrient agar
5, main test instrument: PYX-DHS-50*65 water isolation type electro-heating standing-temperature cultivator, functional.
6, nertralizer: containing 0.3%Na
2s
2o
3+ 0.2% lecithin+0.3%Tween80PBS liquid.
Four, method:
1, detect foundation: the disposable use hygienic article of < < sanitary standard > > GB15979-2002
2, testing conditions: 15 ℃ of test temperatures, relative humidity 50%, (54 ℃ 14 days).
Five, result:
Antibacterial effect to staphylococcus aureus after stability test
Note: test is respectively 7.7*10 by the total number of bacteria of three experiment contrast sheets of staphylococcus aureus (ATCC6538)
4cfu/ sheet, 6.8*10
4cfu/ sheet, 6.2*10
4cfu/ sheet.
Six, conclusion
According to the disposable use hygienic article of < < sanitary standard > > GB15979-2002, Shu Er skin antipruritic water is under experimental condition, effect 2min is 99.9% to the average antibiotic rate of staphylococcus aureus after stability test; Effect 5min, the average antibiotic rate of staphylococcus aureus right after stability test is 100.0%; Effect 10min is 100.0% to the average antibiotic rate of staphylococcus aureus after stability test; Effect 20min is 100.0% to the average antibiotic rate of staphylococcus aureus after stability test; There is antibacterial action.
The microbial contamination of Shu Er skin antipruritic water detects
One, equipment:
1, test specimen: Shu Er skin antipruritic water
2, main test instrument: PYX-DHS-50*65 water isolation type electro-heating standing-temperature cultivator, functional;
LRH-250-G biochemical cultivation case, functional.
Two, method:
1, detect foundation: the disposable use hygienic article of < < sanitary standard > > GB15979-2002
2, testing conditions: 15 ℃ of test temperatures, relative humidity 45%
Three, result:
Microbial contamination testing result
Four, conclusion:
The total number of bacterial colonies of Shu Er skin antipruritic water, staphylococcus aureus, escherichia coli, bacillus pyocyaneus, Hemolytic streptococcus, fungus colony sum meet the regulation of the disposable use hygienic article of < < sanitary standard > > GB15979-2002.
Since 2011, with Shu Er skin antipruritic water, treat various itching skin disease 600 examples, through clinical observation, determined curative effect, existing report is as follows:
1, clinical data
This is organized in 318 routine patients, men and women's no significant difference, wherein acute urticaria 75 examples, chronic urticaria 12 examples, acute and subacute eczema 63 examples, chronic eczema 15 examples, winter dermatitis 10 examples, dermatitis aestivale 51 examples, miliaria 26 examples, other allergic dermatitis 8 examples, senile skin pruritus 11 examples, neurodermatitis 14 examples, other itching skin disease 33 examples; The shortest 10min of the course of disease, the longest 30a; Age was at 6 months-85 years old; All cases all meet the diagnostic criteria of itching skin disease.
2, Therapeutic Method
2.1 medicine
With the optional side of Shu Er skin antipruritic water 1-6 embodiment;
2.2 using method
With cotton swab, dip in liquid medicine and embrocate affected part, 4 times on the one-5 times;
2.3 points for attention
Keep skin clean, change in time underwear, remove irritated factor, the product that fasting is pungent, forbid invading eye, mouth, genitals, scrotum, anus mucosa etc. and locate, anemia of pregnant woman's forbidding.
3, efficacy analysis
3.1 criterion of therapeutical effect
Cure: sings and symptoms disappears, it is normal that skin lesion recovers; Effective: transference cure, skin lesion alleviates or reduces; Invalid: sings and symptoms is without improvement, and skin lesion does not alleviate or reduces.
3.2 therapeutic outcome
Acute urticaria patient all cures at 1d-3d; Allergic dermatitis is all cured; Acute and subacute eczema is cured 102 examples, effective 24 examples, and all the other various itching skin disease are all effective.Effective percentage 100%.After curing, recurrence uses we still effective again.All cases all has no adverse reaction in therapeutic process.
4, model case
Zhao *, 23 years old, workman,, from the beginning of local pruritus, after scratching, there is being dispersed in pimple in general skin pruritus more than 1 year, blood crusts, scratch increase the weight of dysphoria gradually, insomnia, and Zeng township hospital seeks medical advice, through integrative therapy, without improvement, adopt the treatment of Shu Er skin, embrocate 3 days pimples and reduce, skin lesion takes a turn for the better, and embrocates scratchiness and pimple after 1 week and disappears completely, and local skin lesion recovers normally, there is pigmentation, follow up a case by regular visits to and within 1 year, have no recurrence.
Lee *, 48 years old, cadre, before 7 days there is small rice grain sample size pimple in right leg and popliteal nest portion, and pruritus, increases the weight of day by day, and enlarged areas once took Chinese medicine and western medicine, and external-applied ointment is invalid, uses the treatment of Shu Er skin instead, embrocates after 3 days, and it is normal that recover at skin lesion place.
5, discuss
Because pruritus and the anaphylaxis dermatosis cause of disease are complicated, inducement is many, is commonly encountered diseases in department of dermatologry, frequently-occurring disease, account in outpatient service department of dermatologry patient more than 80%, to patient, bring many miseries and inconvenience, the refrigerant anti-inflammatory anti-itch of Herba Menthae in side; Aloe has stronger antibacterial parasite killing antiallergic and antipruritic effect, Folium Pini is the various trace elements such as strong oxidizer and the equal cupric of Agkistrodon halys meat, ferrum, zinc, selenium, Periostracum Serpentis wind dispelling insecticide, Fel Serpentis anti-acne has specially good effect, Periostracum Serpentis has special effect to refractory skin, Fructus Cnidii, Rhizoma Paridis, multiple Serpentis and Camphora and Borneolum Syntheticum fragrance are walked to alter, and anti-inflammation detumescence is antipruritic.All medicines are played the effect of anti-skin allergy altogether, Herba Menthae, Camphora and Borneolum Syntheticum have the function that promotes Drug Percutaneous Absorption in addition, Fructus cnidii extract has inhibitory action to dermatophytess such as acrothesium floccosums, effective to eczema, bleb scabies, pruritus, tinea manus and pedis etc., Rhizoma Paridis has heat-clearing and toxic substances removing anti-inflammatory analgetic, various bacteria virus is all had to bacteriostasis, Flos Chrysanthemi Indici anti-bacteria and anti-virus antiinflammatory skin protection.Therefore we's treatment itching skin disease has the advantage rapid, curative effect is high that takes effect, excellent good for acute anaphylaxis dermatosis effect.The old children of we all should apply; After the patient local applications such as clinical observation diabetes, hypertension, heart disease, Peptic Ulcers, have no adverse reaction and the generation of complication.
Below in conjunction with embodiment, the present invention is further described
Specific implementation method:
Embodiment 1
(1) a Shu Er skin antipruritic water, is characterized in that: each quality of material of Naja Mylabris forms % by following proportioning
(2) Shu Er skin stops an overworked water, it is characterized in that: Agkistrodon halys natural plant water-soluble extract, forms % by following quality proportioning
A, Agkistrodon halys are organized natural plant water-soluble extract
B, compound skin-whitening speckle dispelling Shu Er skin antipruritic water
(3) a Shu Er skin antipruritic water, is characterized in that: Adeps Serpentis Cutis Bufonis crude vegetal forms % by following quality proportioning
(4) a Shu Er skin antipruritic water, is characterized in that: by Zaocys Folium Pini pure natural plant, by following quality proportioning, form %
(5) a Shu Er skin antipruritic water, is characterized in that: by Agkistrodon halys Fel Serpentis Cypress ethereal oil, by following quality proportioning, form %
(6) a Shu Er skin antipruritic water, is characterized in that: by Periostracum Serpentis Fel Sus domestica natural plants, by following quality proportioning, form %
A kind of Shu Er skin antipruritic water, by Naja Mylabris Chinese medicine and western medicine, Agkistrodon halys natural plant water-soluble extract, Adeps Serpentis Cutis Bufonis crude vegetal, Zaocys Folium Pini pure natural plant, Agkistrodon halys Fel Serpentis Cypress ethereal oil, Periostracum Serpentis Fel Sus domestica natural botanical extraction liquid, formed, it is characterized in that: by following quality proportioning, form %
Embodiment 2: a kind of Shu Er skin antipruritic water, by Naja Mylabris Chinese medicine and western medicine, Agkistrodon halys natural plant water-soluble extract, Adeps Serpentis Cutis Bufonis crude vegetal, Zaocys Folium Pini pure natural plant, Agkistrodon halys Fel Serpentis Cypress ethereal oil, Periostracum Serpentis Fel Sus domestica natural botanical extraction liquid, formed, it is characterized in that: by following quality proportioning, form %
Embodiment 3: a kind of Shu Er skin antipruritic water, by Naja Mylabris Chinese medicine and western medicine, Agkistrodon halys natural plant water-soluble extract, Adeps Serpentis Cutis Bufonis crude vegetal, Zaocys Folium Pini pure natural plant, Agkistrodon halys Fel Serpentis Cypress ethereal oil, Periostracum Serpentis Fel Sus domestica natural botanical extraction liquid, formed, it is characterized in that: by following quality proportioning, form %
Embodiment 4: a kind of Shu Er skin antipruritic water, by Naja Mylabris Chinese medicine and western medicine, Agkistrodon halys natural plant water-soluble extract, Adeps Serpentis Cutis Bufonis crude vegetal, Zaocys Folium Pini pure natural plant, Agkistrodon halys Fel Serpentis Cypress ethereal oil, Periostracum Serpentis Fel Sus domestica natural botanical extraction liquid, formed, it is characterized in that: by following quality proportioning, form %
Embodiment 5: a kind of Shu Er skin antipruritic water, by Naja Mylabris Chinese medicine and western medicine, Agkistrodon halys natural plant water-soluble extract, Adeps Serpentis Cutis Bufonis crude vegetal, Zaocys Folium Pini pure natural plant, Agkistrodon halys Fel Serpentis Cypress ethereal oil, Periostracum Serpentis Fel Sus domestica natural botanical extraction liquid, formed, it is characterized in that: by following quality proportioning, form %
Embodiment 6: a kind of Shu Er skin antipruritic water, by Naja Mylabris Chinese medicine and western medicine, Agkistrodon halys natural plant water-soluble extract, Adeps Serpentis Cutis Bufonis crude vegetal, Zaocys Folium Pini pure natural plant, Agkistrodon halys Fel Serpentis Cypress ethereal oil, Periostracum Serpentis Fel Sus domestica natural botanical extraction liquid, formed, it is characterized in that: by following quality proportioning, form %
Claims (1)
1. a Shu Er skin antipruritic water, is characterized in that: by following quality proportioning, form %
(1) a Shu Er skin antipruritic water, is characterized in that: each material of Naja Mylabris forms % by following quality proportioning
(2) a Shu Er skin antipruritic water, is characterized in that: Agkistrodon halys natural plant water-soluble extract forms % by following quality proportioning
A, Agkistrodon halys are organized natural plant water-soluble extract
B, compound skin-whitening speckle dispelling Shu Er skin antipruritic water
(3) a Shu Er skin antipruritic water, is characterized in that: Adeps Serpentis Cutis Bufonis crude vegetal forms % by following quality proportioning
(4) a Shu Er skin antipruritic water, is characterized in that: by Zaocys Folium Pini pure natural plant, by following quality proportioning, form %
(5) a Shu Er skin antipruritic water, is characterized in that: by Agkistrodon halys Fel Serpentis Cypress ethereal oil, by following quality proportioning, form %
(6) a Shu Er skin antipruritic water, is characterized in that: by Periostracum Serpentis Fel Sus domestica natural plants, by following quality proportioning, form %
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107595944A (en) * | 2016-07-08 | 2018-01-19 | 南通蛇类治疗研究所 | Antipruritic water |
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2014
- 2014-06-30 CN CN201410320191.XA patent/CN104069056A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 中华人民共和国卫生部: "《化妆品卫生规范》", 31 January 2007 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107595944A (en) * | 2016-07-08 | 2018-01-19 | 南通蛇类治疗研究所 | Antipruritic water |
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