CN1857493A - Antiseptic for preventing and treating tinea unguium and tinea of feet and hands - Google Patents
Antiseptic for preventing and treating tinea unguium and tinea of feet and hands Download PDFInfo
- Publication number
- CN1857493A CN1857493A CN 200610066219 CN200610066219A CN1857493A CN 1857493 A CN1857493 A CN 1857493A CN 200610066219 CN200610066219 CN 200610066219 CN 200610066219 A CN200610066219 A CN 200610066219A CN 1857493 A CN1857493 A CN 1857493A
- Authority
- CN
- China
- Prior art keywords
- tinea
- parts
- pedis
- radix sophorae
- tinea unguium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The antiseptic for preventing and treating tinea unguium, tinea manus and tinea pedes as one kind of Chinese medicine preparation is prepared with malaytea scurfpea fruit, clove, dried old orange, pseudolarix, flavescent sophora root, garlicin, glacial acetic acid and deionized water in certain weight proportion. The antiseptic of the present invention has simple recipe, convenient use, less irritation and no toxic side effect.
Description
Technical field
A kind of antibacterial that is used for the treatment of and prevents tinea unguium, tinea manus and pedis relates to field of traditional Chinese.
Background technology
Tinea manus and pedis is meant the skin lesion that is caused by fungal infection, and certain infectiousness is arranged, and gives others but self infect and infect.Because hand and foot cutin bed thickness, hyperhidrosis and do not have sebum help the growth and breeding of dermatophytes.Therefore, adolescence and adult's tinea manus and pedis sickness rate height.Tinea manus and pedis is sent out clinically and is antiperspirant scar type, erosive type and squama keratinization type.Antiperspirant scar type is sent out well in an example or both sides and is referred to (toe) most advanced and sophisticated face or palm and vola portion of bending, originally be the full washing basin of heavy wall, be fused into bulla then, bubble liquid is transparent, do not have blush on every side, after scratching often because of the concurrent erysipelas of secondary infection, cellulitis or lymphangitis.That erosive type is sent out well between the 4th toe is moist, dipping turns white or vesicle, does solid back desquamation, and peelling off scurf is rotten to the corn face moistening, flushing, and the patient is odd to itch, easy secondary infection.The squama keratinization type is more common in palm, heel or vola lateral margin, from the beginning of normal no obvious vesicle, is the small pieces squama, and the course of disease is very slow, and Chang Duonian is not healed, and skin follows the string, and that touches is coarse, and chapped skin easily takes place winter.True mattress is a kind of conditioned pathogen, when immune function of human body is vigorous, just be difficult for to think sick, and when resistance of human body descends easy catching an illness.Primary disease is equivalent to categories such as Chinese medicine " fungal infection of hand and foot ", " tinea pedis ".They are sick many because of the damp and hot poison of diseases caused by exogenous pathogenic factor, accumulate long-pending skin; Or taste two are through damp invasion of lower energizer; Or by being in contact with one another, malicious evil infection forms, disease for a long time then QI and blood can not moisten fosterly mutually, skin is done thick cracking from dryness, desquamation.Clinical common pattern of syndrome has:
1. vesicle type: originally card is seen in groups or the pinhead-sized vesicle that is dispersed in, is difficult for breaking.The scar top exfoliation of dry back forms the ring-type squama, and new infringement constantly occurs, and merges mutually, and the edge is clearer.
2. squama keratinization type: card is seen desquamation, and cutin thickens, and pachylosis is dry and cracked, and skin lesion mainly occurs in palm, heel portion etc.
3. immersion-type: card sees that the skin dipping turns white between fingers (toe), often causes the epidermis intertrigo after rubbing because of acutely scratching, and exposes flushing erosion face, can cause secondary infection, as erysipelas, lymphangitis etc.
Tinea unguium is that dermatophytes is invaded caused disease under deck or the first, is divided into amphitypy.The white first of first fungoid, the skin lesion of this type only are confined to first face a slice or its tip; It two is epidermophytosis interdigitales under the deck, and this type pathological changes continues and infects down with the deck from the both sides or the far-end of first.Tinea unguium is meant by non-tinea fungus, tinea unguium, is commonly called as " tinea unguium ".Generally begin morbidity with 1-2 finger (toe) first, weight person refers to that all (toe) first all can suffer from.Ill deck tarnishes, and with the passing of time the deck thickens distortion, is greyish white, turbid yellow.The deck becomes fragile and breakage comes off, and separate with nail matrix on the deck sometimes.
Tinea unguium is that dermatophytes is invaded caused disease under deck or the first, is divided into amphitypy.The white first of first fungoid (shallow white tinea unguium), the skin lesion of this type only is confined to first face a slice or its tip; It two is epidermophytosis interdigitale under the deck (a first mo(u)ld bottom half tinea unguium), and this type pathological changes continues and infects down with the deck from the both sides or the far-end of first.Tinea unguium is meant by fungus-caused first such as non-tinea fungus, yeast and infects.
Refer to (toe) first by the position difference of fungal infection, the position of starting can also can begin morbidity from nail root in the both sides of free-end or first, invades whole finger (toe) first gradually.The common feature of sick first be thicken, variable color (deck becomes dirty yellow, canescence), deck lose former glossy, the surface is uneven, first matter is crisp becomes a large amount of chips of accumulation.The variation of first matter can be on leading edge and surface, form whole thicken first break and damaged; Also can be belowdecks, there is many stars chip to come off between deck and the nail matrix, form both and separate attenuation of deck, top layer and torsional deformation.Amphitypy respectively has characteristics, and division is as follows:
(1) the white first of fungoid: often caused that with granular pattern and refer to that type is more common between (toe), funguses such as cephalosporium salmosinnematum, Fusarium spp. and ashen aspergillosis also can be caused a disease once in a while by trichophyton gypseum.Just arise from the nearly crescentic area of central authorities of deck surface, or the free edge of first or its both sides pleat, be a little muddiness district, often be point-like, profile is irregular, can only have a bit, or a plurality of point.Pathological changes is confined to a place, also can involve to full first.The first face is softer, also can not have any symptom sometimes, infects normal lasting for years.More shallow by the tinea unguium pathological changes that achorion gypseum causes, do not accompany paronychia, desquamation appears in nail matrix pleat skin, and a most part that only involves first, also can involve complete deck sometimes.
The white first disease of fungoid fungal mycelia, majority is confined to the topmost on deck, seldom involves deep layer, and a large amount of mycelia combine in top, deck, compare with the first mo(u)ld bottom half, and mycelia is big and wide seen in the tinea unguium.Mycelia and difform arthrospore that agglomerating swelling is often arranged in the section
(2) first mo(u)ld bottom half tinea unguium: pathological changes starts from both sides, deck or end, and slight paronychia is arranged earlier, becomes chronic inflammatory disease then gradually, also can gradually disappear.Paronychia causes first face concave point or rill, begins to be fleck, and boundary clear is saturating white in yellow or the Huang, lasting constant for a long time, or involves nail root gradually.The deck is in a single day infected, can form crackle, becomes fragile or thickens, and is brown or black, occurs keratin and detrital deposit under the first.Under the normal physiological situation, keratin is synthetic not at nail matrix, and under the deck.After fungus is invaded nail matrix, because stimulation begins to form soft and crisp keratin, therefore make first become crisp, along with the keratin deposition, the deck obviously thickens.This point is obviously different with the candidiasis tinea unguium, and the latter does not often have detrital deposit, and the deck is also many not to be thickened.Nutrients such as nail matrix chip and angle protein help the quick growth of fungus, and fungus just is able to rampantly, below it, invades hard deck, further stimulates nail matrix, compel it and form more angle protein, the deck is become obviously thicken.Certainly other funguses or antibacterial also can be invaded chip portion simultaneously.But nail matrix is not invaded by it often, thereby slight profile change, color and luster variation only occur, and is local phenomenon, but the minority Non Apparent Abnormality.Trichophyton infects the tinea unguium cause, often is deck far-end embrittlement, separation and stays a thin ditch, and its edge roughness when involving full first, is just destroyed full fingernail.
The morbidity of tinea unguium, tinea manus and pedis is all very extensive in worldwide, in the treatment, two kinds of oral and externals is arranged again; Oral antifungal drug, as itraconazole, fluconazol etc., but this class medicine all has certain injury to liver; Modern medicine to the treatment of tinea manus and pedis mainly based on medicine for external use, as whitfield ointment or liniment, miconazole class cream or compound recipe resorcin preparation etc., existing pressing down killed dermatophytes toothed oak usefulness, has cutin to strip off effect again, still, these chemical combination medicaments are cured the symptoms, not the disease, the relapse rate height.
Summary of the invention
An object of the present invention is that oral antifungal drug has injury to liver in the above-mentioned prior art in order to solve, medicine for external use is cured the symptoms, not the disease, and the problem that relapse rate is high provides a kind of antibacterial that is used for the treatment of and prevents tinea unguium, tinea manus and pedis.
Another object of the present invention provides a kind of preparation method that is used for the treatment of and prevents the antibacterial of tinea unguium, tinea manus and pedis.
For achieving the above object, a technical scheme of the present invention provides a kind of antibacterial that is used for the treatment of and prevents tinea unguium, tinea manus and pedis, is made by following substances in parts by weight: Fructus Psoraleae 15-20 part, Flos Caryophylli 5-10 part, Pericarpium Citri Reticulatae 5-10 part, Cortex Pseudolaricis 3-5 part, Radix Sophorae Flavescentis 20-30 part, glacial acetic acid 10-40 part, garlicin 2-5 part, deionized water 50-90 part.
Further say, a kind of antibacterial that is used for the treatment of and prevents tinea unguium, tinea manus and pedis is made by following substances in parts by weight: 18 parts of Fructus Psoraleaes, 8 parts of Flos Caryophyllis, 8 parts of Pericarpium Citri Reticulataes, 4 parts of Cortex Pseudolaricis, 25 parts of Radix Sophorae Flavescentiss, 20 parts in glacial acetic acid, 3 parts of garlicins, 75 parts of deionized waters.
Another technical scheme of the present invention provides a kind of preparation method that is used for the treatment of and prevents the antibacterial of tinea unguium, tinea manus and pedis:
1. Fructus Psoraleae, Flos Caryophylli, Pericarpium Citri Reticulatae, Cortex Pseudolaricis, Radix Sophorae Flavescentis soaked after 1-2 hour, clean silt;
2. Radix Sophorae Flavescentis is thinly sliced, and put to container after Fructus Psoraleae, Flos Caryophylli, Pericarpium Citri Reticulatae, Cortex Pseudolaricis mix, add deionized water and decoct 1-2 hour, take out filtrate then to return filter, filter 23 hour,
3. gained filtrate adding glacial acetic acid, garlicin are got final product.
The PH of products obtained therefrom is between 3 ± 1.
Beneficial effect of the present invention is:
1. prescription is simple, is convenient to use; Compare with the other treatment and the antibacterial of prevention tinea unguium, tinea manus and pedis, different in medication:
Fructus Psoraleae: be conventional Chinese medicine.The function that cures mainly in daily life is a warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.But cooperate with other all medicines at this prescription, play and suppress the synthetic of pathogenic bacteria DNA, simultaneously can infiltrate the pathogenic bacteria dna fragmentation, make the synthetic interruption of DNA chain, suppress duplicating of pathogenic bacteria. for the infectious onychonosus that causes by fungus (tinea unguium), antibacterial (paronychia) etc.s, so important curative effect is arranged. the while Fructus Psoraleae has stronger percutaneous permeability. and skin lower floor is antibacterial certain curative effect to going deep into.
Radix Sophorae Flavescentis: the medical material that also is a kind of extensive use.Radix Sophorae Flavescentis heat clearing and damp drying, diuresis, wind dispelling insecticide dailyly are used for diseases such as scabies stubborn dermatitis, the whole body pruritus due to wind pathogen, damp and hot sore, malignant boil.But Radix Sophorae Flavescentis cooperates with other all medicines in this prescription, can play in the infiltration pathogenic bacteria body and quicken pathogenic bacteria protein coagulation, degeneration, disturbs bacterium enzymatic activity, the metabolism of inhibition zone pathogenic bacteria and growth, changes cell membrane, destroys the pathogenic bacteria physiological function.Except the pathogenic bacteria that can eliminate tinea unguium, tinea manus and pedis, can also play the effect (for example: staphylococcus, escherichia coli etc.) that suppresses other pathogenic bacteria.
2. antibacterial zest of the present invention is little, has no side effect.Because the present invention is guidance with motherland's theory of medicine, with scientific formula, has greatly brought into play the effect of every kind of composition, various compositions are assisted a ruler in governing a country mutually and are cooperatively interacted, and have played unforeseeable effect.
The specific embodiment
Enumerate embodiment below, the present invention is further specified, but the present invention is not only limited to these embodiment.
Embodiment 1
Get Fructus Psoraleae 18kg, Flos Caryophylli 8kg, Pericarpium Citri Reticulatae 8kg, Cortex Pseudolaricis 4kg, Radix Sophorae Flavescentis 25kg, deionized water 75kg.Fructus Psoraleae, Flos Caryophylli, Pericarpium Citri Reticulatae, Cortex Pseudolaricis, Radix Sophorae Flavescentis are soaked after 1-2 hour, clean silt; Radix Sophorae Flavescentis is cut into the thick thin slice of 1-3mm, and puts to stainless steel cask after Fructus Psoraleae, Flos Caryophylli, Pericarpium Citri Reticulatae, Cortex Pseudolaricis mix, add deionized water and decoct 1-2 hour, take out filtrate then to return filter, filter 23 hour,
Take by weighing Chinese medicine extract 5kg, glacial acetic acid 20kg, garlicin 3kg is adjusted to gained filtrate adding garlicin, adding glacial acetic acid PH=3 and gets final product.
Embodiment 2-8
According to the antibacterial of the described method manufacturing treatment of embodiment 1 and prevention tinea unguium, tinea manus and pedis, described raw material consumption such as following table:
| Raw material (kg) | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 | Embodiment 7 | Embodiment 8 |
| Fructus Psoraleae | 15 | 20 | 16 | 17 | 18 | 19 | 17.5 |
| Flos Caryophylli | 6 | 7 | 5 | 10 | 8 | 9 | 7.5 |
| Pericarpium Citri Reticulatae | 5 | 10 | 8 | 9 | 7.5 | 6 | 7 |
| Cortex Pseudolaricis | 3 | 3.5 | 4 | 4.5 | 5 | 4.2 | 3.8 |
| Radix Sophorae Flavescentis | 20 | 30 | 25 | 22 | 26 | 28 | 24 |
| Glacial acetic acid | 10 | 20 | 30 | 40 | 25.5 | 32.8 | 22.2 |
| Deionized water | 50 | 60 | 70 | 80 | 90 | 75.5 | 62.5 |
| Garlicin | 2 | 3 | 4 | 5 | 2.4 | 3.5 | 4.5 |
Above-mentioned each raw material is commercially available
Claims (3)
1. an antibacterial that is used for the treatment of and prevents tinea unguium, tinea manus and pedis is made by following substances in parts by weight: Fructus Psoraleae 15-20 part, Flos Caryophylli 5-10 part, Pericarpium Citri Reticulatae 5-10 part, Cortex Pseudolaricis 3-5 part, Radix Sophorae Flavescentis 20-30 part, glacial acetic acid 10-40 part, garlicin 2-5 part, deionized water 50-90 part.
2. according to the described antibacterial that is used for the treatment of and prevents tinea unguium, tinea manus and pedis of claim 1, it is characterized in that, make: 18 parts of Fructus Psoraleaes, 8 parts of Flos Caryophyllis, 8 parts of Pericarpium Citri Reticulataes, 4 parts of Cortex Pseudolaricis, 25 parts of Radix Sophorae Flavescentiss, 20 parts in glacial acetic acid, 3 parts of garlicins, 75 parts of deionized waters by following substances in parts by weight.
3. according to the described preparation method that is used for the treatment of and prevents the antibacterial of tinea unguium, tinea manus and pedis of claim 1, it is characterized in that the step of this method is as follows:
1). Fructus Psoraleae, Flos Caryophylli, Pericarpium Citri Reticulatae, Cortex Pseudolaricis, Radix Sophorae Flavescentis are soaked after 1-2 hour, clean silt;
2). Radix Sophorae Flavescentis is thinly sliced, and put to container after Fructus Psoraleae, Flos Caryophylli, Pericarpium Citri Reticulatae, Cortex Pseudolaricis mix, add deionized water and decoct 1-2 hour, take out filtrate then to return filter, filter 23 hour;
3). gained filtrate adding glacial acetic acid, garlicin are got final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100662197A CN100404046C (en) | 2006-03-29 | 2006-03-29 | Antiseptic for preventing and treating tinea unguium and tinea of feet and hands |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100662197A CN100404046C (en) | 2006-03-29 | 2006-03-29 | Antiseptic for preventing and treating tinea unguium and tinea of feet and hands |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1857493A true CN1857493A (en) | 2006-11-08 |
| CN100404046C CN100404046C (en) | 2008-07-23 |
Family
ID=37296481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006100662197A Expired - Fee Related CN100404046C (en) | 2006-03-29 | 2006-03-29 | Antiseptic for preventing and treating tinea unguium and tinea of feet and hands |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100404046C (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104116964A (en) * | 2014-07-15 | 2014-10-29 | 太仓思瑞生物科技有限公司 | Application of traditional Chinese medicine preparation on treating onychomycosis |
| CN104127744A (en) * | 2014-07-15 | 2014-11-05 | 太仓思瑞生物科技有限公司 | External traditional Chinese medicinal preparation for treating leuconychia |
| CN104127807A (en) * | 2014-07-15 | 2014-11-05 | 太仓思瑞生物科技有限公司 | Use of traditional Chinese medicinal composition in onychomycosis treatment |
| CN104435717A (en) * | 2014-12-30 | 2015-03-25 | 武汉美邦生物科技有限公司 | Traditional Chinese medicine for treating ringworm of fingernails or toenails and tinea of feet and hands and preparation method thereof |
| CN110151916A (en) * | 2019-06-24 | 2019-08-23 | 刘决梅 | A kind of ointment and preparation method thereof for treating onychomycosis |
| CN115779030A (en) * | 2022-12-29 | 2023-03-14 | 陕西周地岐轩堂中医药有限公司 | Nail beautifying liquid for treating onychomycosis and formula thereof |
-
2006
- 2006-03-29 CN CNB2006100662197A patent/CN100404046C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104116964A (en) * | 2014-07-15 | 2014-10-29 | 太仓思瑞生物科技有限公司 | Application of traditional Chinese medicine preparation on treating onychomycosis |
| CN104127744A (en) * | 2014-07-15 | 2014-11-05 | 太仓思瑞生物科技有限公司 | External traditional Chinese medicinal preparation for treating leuconychia |
| CN104127807A (en) * | 2014-07-15 | 2014-11-05 | 太仓思瑞生物科技有限公司 | Use of traditional Chinese medicinal composition in onychomycosis treatment |
| CN104435717A (en) * | 2014-12-30 | 2015-03-25 | 武汉美邦生物科技有限公司 | Traditional Chinese medicine for treating ringworm of fingernails or toenails and tinea of feet and hands and preparation method thereof |
| CN110151916A (en) * | 2019-06-24 | 2019-08-23 | 刘决梅 | A kind of ointment and preparation method thereof for treating onychomycosis |
| CN115779030A (en) * | 2022-12-29 | 2023-03-14 | 陕西周地岐轩堂中医药有限公司 | Nail beautifying liquid for treating onychomycosis and formula thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100404046C (en) | 2008-07-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100404046C (en) | Antiseptic for preventing and treating tinea unguium and tinea of feet and hands | |
| KR20160006812A (en) | Compositions for preventing and curing diabetes comprising extract of Paeonia lactiflora | |
| CN114028511B (en) | Traditional Chinese medicine composition for treating intractable gout and application thereof | |
| CN1733166A (en) | Chinese traditional medicine preparation for curing gastric ulcer | |
| CN115624584A (en) | Traditional Chinese medicine composition for treating frostbite | |
| CN101049362A (en) | External remedy for treating onychomycosis | |
| CN101129559A (en) | Lianqin liquor for treating beriberi | |
| CN103230418B (en) | Mycelium extract for helicobacter pylori-resistant biological medicine and preparation technology thereof | |
| CN1264536C (en) | Anti-gout composition and preparing process thereof | |
| CN1215876C (en) | Antigout medicinal composition and its preparing method | |
| CN104173873A (en) | External ointment for treating onychomycosis | |
| CN100349583C (en) | Chinese traditional medicine for treating chronic nephritis | |
| CN102697965A (en) | Traditional Chinese medicine composition for treating tinea pedis | |
| CN1104253C (en) | Medicine for strengthening physique and strengthening immunity | |
| CN104225402B (en) | Traditional Chinese medicine composition for removing tinea and treating tinea pedis | |
| CN116270922B (en) | Prescription for eliminating turbid pathogen, resolving masses and removing arthralgia and application thereof | |
| CN107823301A (en) | A kind of external medicinal liquid for treating onychomycosis and preparation method thereof | |
| CN116211923B (en) | Traditional Chinese medicine medicated bath preparation for treating tinea, and preparation method and application thereof | |
| CN116270873B (en) | Traditional Chinese medicine composition for treating dermatophyte infection | |
| CN1270038A (en) | Fumigant lotion for treating anorectal disease and preparing process thereof | |
| CN1895385A (en) | Chinese-medicinal aqua for treating hand-foot ring worms | |
| CN100335099C (en) | Externally applied pure Chinese medicinal tincture for treating manus and pedes tinea | |
| CN1259948C (en) | External-applying treating liquid for rhinitis and common cold, and its preparation method thereof | |
| CN112704720A (en) | Pharmaceutical composition with nail-dissolving effect and application thereof | |
| CN105194072A (en) | Traditional Chinese medicine composition with efficacy of assisting in treatment of pulmonary infection |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080723 Termination date: 20100329 |