CN105147583B - A kind of children special-purpose toothpaste containing Sasanguasaponin and preparation method thereof - Google Patents
A kind of children special-purpose toothpaste containing Sasanguasaponin and preparation method thereof Download PDFInfo
- Publication number
- CN105147583B CN105147583B CN201510638136.XA CN201510638136A CN105147583B CN 105147583 B CN105147583 B CN 105147583B CN 201510638136 A CN201510638136 A CN 201510638136A CN 105147583 B CN105147583 B CN 105147583B
- Authority
- CN
- China
- Prior art keywords
- parts
- tea
- component
- solid
- children
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of children special-purpose toothpaste containing Sasanguasaponin and preparation method thereof, its is raw materials used to include by weight：Oil-tea-cake or 58 parts of degreasing tea seed, 13 parts of gleditsia sinensis, 0.5 2 parts of wild tea oil, 13 parts of vine tea, 0.5 1 parts of rosemary, 13 parts of hypericum perforatum, 0.5 1 parts of Momordica grosvenori, 10 15 parts of watermelon seeds, 10 15 parts of egg shell, 13 parts of indigo naturalis, 0.5 1 parts of citric acid, 0.5 1 parts of sodium citrate, 1 part of CMC0.5,20 35 parts of deionized water.The present invention prepares a kind of toothpaste for being exclusively used in children by component of natural plants such as oil tea, gleditsia sinensis, vine teas; its tooth to children has cleaning whitening and protective effect well; the problem of can preventing children from easily being decayed tooth because of sweet tooth; effectively reduce the common oral problems such as bacterial plaque; and fragrance and effect component can be anti-halitosis, can reduce the generation of canker sore, sphagitis etc..
Description
Technical field
The invention belongs to daily chemical product preparing technical field, and in particular to a kind of children special-purpose toothpaste containing Sasanguasaponin and
Its preparation method.
Background technology
Toothpaste is a kind of indispensable articles for daily use, not only has cleaning whitening function well to tooth, also protects
Dental health, ensure the effect such as oral hygiene, What is more can adjust the mood of people, influence the health of human body.At present, state of China
The toothpaste that interior in the market is sold is more based on toothpaste of being grown up, and it is less to be exclusively used in the product of children's toothpaste, and most of children's toothpaste
Mainly reach mothproof effect by fluoride, but fluorine element is entered into the human body by oral mucosa, can cause fluorine occur
Dental plaque, even there are the diseases such as fluorosis of bone.Therefore, various countries oral cavity expert is it is not recommended that children use toothpaste with fluoride, in order to avoid children
During brushing teeth, due to unconsciously swallowing toothpaste or adhesive sticker of gargling after brushing teeth, make fluorine residue in oral cavity and cause disease
Disease.
The content of the invention
It is an object of the invention to provide a kind of children special-purpose toothpaste containing Sasanguasaponin and preparation method thereof, it uses day
Right plant as primary raw material, the obtained children special-purpose toothpaste containing Sasanguasaponin have to teenager teeth cleaning whitening well with
Protective effect, the problem of can preventing children from easily being decayed tooth because of sweet tooth, effectively control oral cavity bacterial growth, reduce bacterial plaque,
The common oral problem such as gum problem and dentine hypersensitivity, calculus dentalis, and its fragrance and effect component can not only keep oral cavity
It is pure and fresh, it can also reduce the generation of depressive emotion, canker sore, sphagitis etc..
To achieve the above object, the technical solution adopted by the present invention is：
A kind of children special-purpose toothpaste containing Sasanguasaponin, its is raw materials used to include by weight：Oil-tea-cake or degreasing tea
Seed 5-8 parts, gleditsia sinensis 1-3 parts, wild tea oil 0.5-2 parts, vine tea 1-3 parts, rosemary 0.5-1 parts, hypericum perforatum 1-3 parts, Momordica grosvenori
0.5-1 parts, watermelon seeds 10-15 parts, egg shell 10-15 parts, indigo naturalis 1-3 parts, citric acid 0.5-1 parts, sodium citrate 0.5-1 parts,
CMC 0.5-1 parts, deionized water 20-35 parts.
The preparation method of the children special-purpose toothpaste containing Sasanguasaponin comprises the following steps：
1）Oil-tea-cake or degreasing tea seed, gleditsia sinensis are crushed to 10 ~ 20 mesh jointly, then extracted twice in more than 95 DEG C, the
Once press solid-liquid ratio 1:25 plus flooding 35min, press solid-liquid ratio 1 for the second time:15 plus flooding 20min, then by two-stage leaching
Liquid merges, and through disk centrifugal, ultrafiltration, the reverse osmosis concentrated soluble solid content that is reduced to up to 30 Brix-35 Brix, obtains component A；
2）Vine tea, rosemary, indigo naturalis are mixed, by solid-liquid ratio 1:28 add water ultrasonic extraction 30min, ultrasound at 100 DEG C
Frequency is 40-80kHZ, and then filtered, tubular type centrifugation, ultrafiltration, the reverse osmosis concentrated soluble solid content that is reduced to are up to 25
Brix-35 Brix, obtain component B；
3）After watermelon seeds, egg shell are fully dried, use ball mill to be crushed to granularity as 500 ~ 800 mesh, obtain component C；
4）Wild tea oil and CMC are mixed into obtain component D；
5）Hypericum perforatum is used and presses solid-liquid ratio 1 with 80 DEG C of water:10 extraction 20min, abandon its leachate, residue is in 75 DEG C
Under, by solid-liquid ratio 1:25 add the alcohol steep 1.5h that mass fraction is 80%, are filtered while hot, filtrate is reclaimed with rotary evaporation
After ethanol, component E is obtained；
6）Momordica grosvenori is subjected to skin breaking, solid-liquid ratio 1 is pressed at 95-100 DEG C:32 plus flooding 1.5h, filtering, filter residue
Solid-liquid ratio 1 is pressed again:16 plus flooding 0.5h, merging filtrate, centrifuged through tubular type, ultrafiltration, be concentrated into soluble solid content and reach
30 Brix, obtain component F；
7）Component B, E, F are added in component A and are heated to 45 DEG C, component D mixings is then gradually added into and is emulsified, by it
It is placed in colloid mill and adds component C and fully stir evenly, then its pH value is adjusted to 7.2-7.6 with citric acid and sodium citrate, and adds
Entering deionized water makes the viscosity of lotion in 13kPas, lotion is carried out under -0.085 ~ -0.090Mpa pressure vacuum outgas,
Tinning, finished product.
The present invention using the saponin(e extracted from tea seed, gleditsia sinensis as surfactant and emulsifying agent, using wild tea oil as
Wetting agent, antioxidant, using the extract of Momordica grosvenori as the sweetener of toothpaste, it is equipped with vine tea, rosemary, indigo naturalis, passes through leaf company
The botanical extract such as stick up, prepare a kind of tooth paste product for being exclusively used in children.The toothpaste has prominent cleaning tooth, protection
Oral cavity, anti-halitosis, prevention depression and other effects, can effectively control oral cavity bacterial growth, reduce bacterial plaque, gum problem and dentine
The common oral problem such as sensitivity, calculus dentalis.Wherein, wild tea oil contains the compositions such as higher unrighted acid, squalene, VE,
There are good moisturizing and antioxidation, oral cavity and lip can be made excessively not to dry；Sasanguasaponin in oil tea, HLB value are
16, there are emulsification, dirt-removing power, and have good bacteriostasis well, and two kinds of gleditsia sinensis saponin(e is planted physical property surfactant and matched somebody with somebody
Close using can both produce certain foam, there is good pure white and antibacterial action again, can effectively prevent the excessive breeding of bacterial fungus
The halitosis or bacterial plaque of formation；Vine tea contains abundant dihydromyricetin, can be good at antibacterial, anti-inflammatory, eliminates free radical, from
And play the effect such as the gum that takes care of one's teeth, pre- anti-halitosis and decayed tooth, anti-calculus dentalis；Hypericum perforatum contain it is abundant, can prevent suppression
The composition of strongly fragrant mood --- hypericin, applied in toothpaste, prevention can be played to children by the absorption of oral epithelium
The effect of depressive emotion；Main component indigo red, couroupitine A in indigo naturalis etc. have very strong bacteriostasis, it is often more important that, its
Can heat-clearing, cool blood, prevention and treatment canker sore and gum pain, this not only has good protective effect in itself to toothpaste, and
It can be played an important role for preventing and treating children's decayed tooth；The sweet taste of Momordica grosvenori is 100-300 times of sweetness of cane sugar, is a kind of natural peace
Full sweetener, while it contains abundant amino acid and vitamin, uses and can may be used also with nutrition oral cavity, gum in toothpaste
To prevent throat inflammation；The fragrance of rosemary plays conclusive effect for the odor type of toothpaste, while also has very strong antibacterial
Effect, can prevent halitosis well, keep the health in oral cavity；CMC is sodium carboxymethylcellulose, and it, which has, preferably promotees to become, increases
The important function such as thick, retentiveness, toothpaste can be made to be not easy separation of solid and liquid and certain shape can be kept.
The remarkable advantage of the present invention is：Children special-purpose toothpaste of the invention containing Sasanguasaponin is by various plants extract
It is formulated with natural component, has cleaning, whitening function well to the tooth of children, be especially their ability to prevention decayed tooth, can
The problem of preventing children from easily being decayed tooth because of sweet tooth.Children special-purpose toothpaste of the present invention does not have excitant to oral epithelium, effectively
Control oral cavity bacterial growth, reduce the common oral problems such as bacterial plaque, gum problem and dentine hypersensitivity, calculus dentalis, its fragrance
And the fragrance of constituent part, bacteriostasis can play and prevent halitosis, pleasant mood etc. from acting on, and there is moisture-keeping function to oral cavity,
Excitant is small, safe, functional, is especially suitable for children's use.
Embodiment
In order that content of the present invention easily facilitates understanding, with reference to embodiment to of the present invention
Technical scheme is described further, but the present invention is not limited only to this.
Embodiment 1
A kind of children special-purpose toothpaste containing Sasanguasaponin, its is raw materials used to include by weight：5 parts of Oil-tea-cake, gleditsia sinensis 1
Part, 0.5 part of wild tea oil, 1 part of vine tea, 0.5 part of rosemary, 1 part of hypericum perforatum, 0.5 part of Momordica grosvenori, 10 parts of watermelon seeds, egg shell
10 parts, 1 part of indigo naturalis, 0.5 part of citric acid, 0.5 part of sodium citrate, 0.5 part of CMC, 20 parts of deionized water.
The preparation method of the children special-purpose toothpaste containing Sasanguasaponin comprises the following steps：
1）Oil-tea-cake, gleditsia sinensis are crushed to 10 mesh jointly, then extracted twice in more than 95 DEG C, for the first time by solid-liquid ratio 1:
25 plus flooding 35min, press solid-liquid ratio 1 for the second time:15 plus flooding 20min, then two-stage leaching liquid is merged, through dish-style from
The heart, ultrafiltration, the reverse osmosis concentrated soluble solid content that is reduced to obtain component A up to 30 Brix；
2）Vine tea, rosemary, indigo naturalis are mixed, by solid-liquid ratio 1:28 add water ultrasonic extraction 30min, ultrasound at 100 DEG C
Frequency is 40-80kHZ, and then filtered, tubular type centrifugation, ultrafiltration, the reverse osmosis concentrated soluble solid content that is reduced to are up to 25
Brix, obtain component B；
3）After watermelon seeds, egg shell are fully dried, use ball mill to be crushed to granularity as 500 mesh, obtain component C；
4）Wild tea oil and CMC are mixed into obtain component D；
5）Hypericum perforatum is used and presses solid-liquid ratio 1 with 80 DEG C of water:10 extraction 20min, abandon its leachate, residue is in 75 DEG C
Under, by solid-liquid ratio 1:25 add the alcohol steep 1.5h that mass fraction is 80%, are filtered while hot, filtrate is reclaimed with rotary evaporation
After ethanol, component E is obtained；
6）Momordica grosvenori is subjected to skin breaking, solid-liquid ratio 1 is pressed at 95 DEG C:32 plus flooding 1.5h, filtering, filter residue are pressed again
Solid-liquid ratio 1:16 plus flooding 0.5h, merging filtrate, centrifuged through tubular type, ultrafiltration, be concentrated into soluble solid content up to 30
Brix, obtain component F；
7）Component B, E, F are added in component A and are heated to 45 DEG C, component D mixings is then gradually added into and is emulsified, by it
It is placed in colloid mill and adds component C and fully stir evenly, then its pH value is adjusted to 7.2 with citric acid and sodium citrate, and adds and go
Ionized water makes the viscosity of lotion that lotion be carried out into vacuum outgas, tinning under the pressure more than -0.094Mpa in 13kPas,
Finished product.
Embodiment 2
A kind of children special-purpose toothpaste containing Sasanguasaponin, its is raw materials used to include by weight：6 parts of degreasing tea seed, soap
2 parts of angle, 1.0 parts of wild tea oil, 2 parts of vine tea, 0.8 part of rosemary, 2 parts of hypericum perforatum, 0.8 part of Momordica grosvenori, 12 parts of watermelon seeds, egg
13 parts of shell, 2 parts of indigo naturalis, 0.8 part of citric acid, 0.8 part of sodium citrate, 0.6 part of CMC, 28 parts of deionized water.
The preparation method of the children special-purpose toothpaste containing Sasanguasaponin comprises the following steps：
1）Degreasing tea seed, gleditsia sinensis are crushed to 10 mesh jointly, then extracted twice in more than 95 DEG C, for the first time by solid-liquid ratio
1:25 plus flooding 35min, press solid-liquid ratio 1 for the second time:15 plus flooding 20min, then merges two-stage leaching liquid, through dish-style
Centrifugation, ultrafiltration, the reverse osmosis concentrated soluble solid content that is reduced to reach 30Brix, obtain component A；
2）Vine tea, rosemary, indigo naturalis are mixed, by solid-liquid ratio 1:28 add water ultrasonic extraction 30min, ultrasound at 100 DEG C
Frequency is 40-80kHZ, and then filtered, tubular type centrifugation, ultrafiltration, the reverse osmosis concentrated soluble solid content that is reduced to are up to 35
Brix, obtain component B；
3）After watermelon seeds, egg shell are fully dried, use ball mill to be crushed to granularity as 600 mesh, obtain component C；
4）Wild tea oil and CMC are mixed into obtain component D；
5）Hypericum perforatum is used and presses solid-liquid ratio 1 with 80 DEG C of water:10 extraction 20min, abandon its leachate, residue is in 75 DEG C
Under, by solid-liquid ratio 1:25 add the alcohol steep 1.5h that mass fraction is 80%, are filtered while hot, filtrate is reclaimed with rotary evaporation
After ethanol, component E is obtained；
6）Momordica grosvenori is subjected to skin breaking, solid-liquid ratio 1 is pressed at 97 DEG C:32 plus flooding 1.5h, filtering, filter residue are pressed again
Solid-liquid ratio 1:16 plus flooding 0.5h, merging filtrate, centrifuged through tubular type, ultrafiltration, be concentrated into soluble solid content up to 30
Brix, obtain component F；
7）Component B, E, F are added in component A and are heated to 45 DEG C, component D mixings is then gradually added into and is emulsified, by it
It is placed in colloid mill and adds component C and fully stir evenly, then its pH value is adjusted to 7.5 with citric acid and sodium citrate, and adds and go
Ionized water makes the viscosity of lotion that lotion be carried out into vacuum outgas, tinning under the pressure more than -0.094Mpa in 13kPas,
Finished product.
Embodiment 3
A kind of children special-purpose toothpaste containing Sasanguasaponin, its is raw materials used to include by weight：8 parts of Oil-tea-cake, gleditsia sinensis 3
Part, 2 parts of wild tea oil, 3 parts of vine tea, 1 part of rosemary, 3 parts of hypericum perforatum, 1 part of Momordica grosvenori, 15 parts of watermelon seeds, 15 parts of egg shell, green grass or young crops
3 parts of black pigment used by women in ancient times to paint their eyebrows, 1 part of citric acid, 1 part of sodium citrate, 1 part of CMC, 35 parts of deionized water.
The preparation method of the children special-purpose toothpaste containing Sasanguasaponin comprises the following steps：
1）Oil-tea-cake, gleditsia sinensis are crushed to 20 mesh jointly, then extracted twice in more than 95 DEG C, for the first time by solid-liquid ratio 1:
25 plus flooding 35min, press solid-liquid ratio 1 for the second time:15 plus flooding 20min, then two-stage leaching liquid is merged, through dish-style from
The heart, ultrafiltration, the reverse osmosis concentrated soluble solid content that is reduced to obtain component A up to 35 Brix；
2）Vine tea, rosemary, indigo naturalis are mixed, by solid-liquid ratio 1:28 add water ultrasonic extraction 30min, ultrasound at 100 DEG C
Frequency is 40-80kHZ, and then filtered, tubular type centrifugation, ultrafiltration, the reverse osmosis concentrated soluble solid content that is reduced to are up to 35
Brix, obtain component B；
3）After watermelon seeds, egg shell are fully dried, use ball mill to be crushed to granularity as 800 mesh, obtain component C；
4）Wild tea oil and CMC are mixed into obtain component D；
5）Hypericum perforatum is used and presses solid-liquid ratio 1 with 80 DEG C of water:10 extraction 20min, abandon its leachate, residue is in 75 DEG C
Under, by solid-liquid ratio 1:25 add the alcohol steep 1.5h that mass fraction is 80%, are filtered while hot, filtrate is reclaimed with rotary evaporation
After ethanol, component E is obtained；
6）Momordica grosvenori is subjected to skin breaking, solid-liquid ratio 1 is pressed at 100 DEG C:32 plus flooding 1.5h, filtering, filter residue is again
By solid-liquid ratio 1:16 plus flooding 0.5h, merging filtrate, centrifuged through tubular type, ultrafiltration, be concentrated into soluble solid content up to 30
Brix, obtain component F；
7）Component B, E, F are added in component A and are heated to 45 DEG C, component D mixings is then gradually added into and is emulsified, by it
It is placed in colloid mill and adds component C and fully stir evenly, then its pH value is adjusted to 7.6 with citric acid and sodium citrate, and adds and go
Ionized water makes the viscosity of lotion that lotion be carried out into vacuum outgas, tinning under the pressure more than -0.094Mpa in 13kPas,
Finished product.
Performance test
1st, organoleptic attribute：Toothpaste prepared by embodiment 1-3 is clean, uniform, fine and smooth, color and luster is normal, is changed with dense fan
Fragrance.
2nd, physical and chemical index：Between toothpaste denseness prepared by embodiment 1-3 is 12 ~ 25, squeezes cream pressure and be less than 40kPa, foam
Measure moderate（60mm or so）, lotion will not automatically overflow, will not separate out water, there is preferable stability.
3rd, toothpaste primary efficacy clinical test
The investigation of decayed tooth situation is carried out respectively to the children of all private kindergartens in pilot region, it is found that its children is decayed tooth
Rate is in the range of 5.7%-8.3%.Four consistent private kindergartens of selection scale as subjects, be denoted as school 1,
School 2, school 3, school 4, to the children of school 2 and school 3, everyone distributes four bottles of children special-purpose toothpaste of the present invention, it is desirable to Yu Zao
Respectively used once when evening brushes teeth, and exhort parent while coordinate supervision service condition, in addition the 2 commercially available children of learning handed down in a family school normal use
Toothpaste, the investigation of decayed tooth situation is carried out after half a year again, the results are shown in Table 1.
The children of table 1 use the decayed tooth rate result of the test of toothpaste
Shown from the result of table 1, the children of the Liang Ge schools of toothpaste of the present invention are not used, and its decayed tooth rate has a certain degree of increasing
Height, and use the decayed tooth rate of the Liang Ge schools of the toothpaste of the present invention constant, or even have certain reduction, illustrate children's tooth of the present invention
Cream has obvious action for preventing and treating decayed tooth.
The foregoing is only presently preferred embodiments of the present invention, all equivalent changes done according to scope of the present invention patent with
Modification, it should all belong to the covering scope of the present invention.
Claims (6)
- A kind of 1. preparation method of the children special-purpose toothpaste containing Sasanguasaponin, it is characterised in that：Comprise the following steps：1）Oil-tea-cake or degreasing tea seed, gleditsia sinensis are crushed to 10 ~ 20 mesh jointly, then through extracting, centrifuging, it is ultrafiltration, reverse osmosis concentrated Soluble solid content is reduced to up to 30 Brix-35 Brix, obtains component A；2）Vine tea, rosemary, indigo naturalis are mixed, through ultrasonic extraction, filtering, centrifugation, ultrafiltration, reverse osmosis concentrated are reduced to soluble solid Thing content obtains component B up to 25 Brix-35 Brix；3）After watermelon seeds, egg shell are fully dried, use ball mill to be crushed to granularity as 500 ~ 800 mesh, obtain component C；4）Wild tea oil and CMC are mixed into obtain component D；5）Hypericum perforatum is once abandoned into its leachate with hot water extraction, residue is extracted with ethanol, and filtrate reclaims second with rotary evaporation After alcohol, component E is obtained；6）Momordica grosvenori is subjected to skin breaking, extraction twice, merging filtrate, through centrifugation, ultrafiltration, is concentrated into soluble solid and contained Amount obtains component F up to 30 Brix；7）Component B, E, F are added in component A and are heated to 45 DEG C, component D mixings is then gradually added into and is emulsified, is placed on In colloid mill and add component C and fully stir evenly, then its pH value is adjusted to 7.2-7.6 with citric acid and sodium citrate, and add and go Ionized water makes the viscosity of lotion that lotion be carried out into vacuum outgas, tinning, finished product in 13kPas；Wherein, it is raw materials used to be calculated as by weight：Oil-tea-cake or degreasing tea seed 5-8 parts, gleditsia sinensis 1-3 parts, wild tea oil 0.5-2 parts, Vine tea 1-3 parts, rosemary 0.5-1 parts, hypericum perforatum 1-3 parts, Momordica grosvenori 0.5-1 parts, watermelon seeds 10-15 parts, egg shell 10-15 Part, indigo naturalis 1-3 parts, citric acid 0.5-1 parts, sodium citrate 0.5-1 parts, CMC 0.5-1 parts, deionized water 20-35 parts.
- 2. the preparation method of the children special-purpose toothpaste containing Sasanguasaponin according to claim 1, it is characterised in that：Step 1）Institute It is specifically to be extracted twice in more than 95 DEG C to state extraction, for the first time by solid-liquid ratio 1:25 plus flooding 35min, press solid-liquid ratio for the second time 1:15 plus flooding 20min, then merges two-stage leaching liquid.
- 3. the preparation method of the children special-purpose toothpaste containing Sasanguasaponin according to claim 1, it is characterised in that：Step 2）Institute It is by solid-liquid ratio 1 at 100 DEG C to state ultrasonic extraction:28 add water ultrasonic extraction 30min, supersonic frequency 40-80kHZ.
- 4. the preparation method of the children special-purpose toothpaste containing Sasanguasaponin according to claim 1, it is characterised in that：Step 5）In The hot water extraction is by solid-liquid ratio 1 by hypericum perforatum with 80 DEG C of water:10 extraction 20min；The ethanol extraction is by the residue after hot water extraction at 75 DEG C, by solid-liquid ratio 1:25 add the second that mass fraction is 80% Alcohol extracts 1.5h, is filtered while hot.
- 5. the preparation method of the children special-purpose toothpaste containing Sasanguasaponin according to claim 1, it is characterised in that：Step 6）In Extraction is by solid-liquid ratio 1 at 95-100 DEG C twice:32 plus flooding 1.5h, filtering, filter residue press solid-liquid ratio 1 again:16 add water logging Carry 0.5h.
- 6. the preparation method of the children special-purpose toothpaste containing Sasanguasaponin according to claim 1, it is characterised in that：Step 7）In The pressure of vacuum outgas is -0.085 ~ -0.090MPa.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510638136.XA CN105147583B (en) | 2015-09-30 | 2015-09-30 | A kind of children special-purpose toothpaste containing Sasanguasaponin and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510638136.XA CN105147583B (en) | 2015-09-30 | 2015-09-30 | A kind of children special-purpose toothpaste containing Sasanguasaponin and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105147583A CN105147583A (en) | 2015-12-16 |
| CN105147583B true CN105147583B (en) | 2018-01-02 |
Family
ID=54788880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510638136.XA Active CN105147583B (en) | 2015-09-30 | 2015-09-30 | A kind of children special-purpose toothpaste containing Sasanguasaponin and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105147583B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106420552A (en) * | 2016-08-31 | 2017-02-22 | 福建省梦娇兰日用化学品有限公司 | Special toothpaste containing multiple components from natural sources for children |
| CN106727024A (en) * | 2017-01-13 | 2017-05-31 | 华南理工大学 | A kind of oil tea gargle and preparation method thereof |
| CN109157421A (en) * | 2018-08-03 | 2019-01-08 | 李守林 | Green and healthy toothpaste cream of microvesicle washing function and the preparation method and application thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101327178A (en) * | 2007-12-22 | 2008-12-24 | 河南理工大学 | Children toothpaste prescription without harm after being swallowed |
| CN102499903A (en) * | 2012-01-06 | 2012-06-20 | 广州薇美姿个人护理用品有限公司 | Oral cavity caring toothpaste composition for children |
| CN103432062A (en) * | 2013-09-11 | 2013-12-11 | 肖秀萍 | Multifunctional Chinese herbal medicine toothpaste and preparation method thereof |
| CN104825368A (en) * | 2015-05-26 | 2015-08-12 | 陈琳仁 | Natural plant active toothpaste and preparation method thereof |
| CN104905987A (en) * | 2015-05-29 | 2015-09-16 | 广州立白企业集团有限公司 | Child toothpaste composition |
-
2015
- 2015-09-30 CN CN201510638136.XA patent/CN105147583B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101327178A (en) * | 2007-12-22 | 2008-12-24 | 河南理工大学 | Children toothpaste prescription without harm after being swallowed |
| CN102499903A (en) * | 2012-01-06 | 2012-06-20 | 广州薇美姿个人护理用品有限公司 | Oral cavity caring toothpaste composition for children |
| CN103432062A (en) * | 2013-09-11 | 2013-12-11 | 肖秀萍 | Multifunctional Chinese herbal medicine toothpaste and preparation method thereof |
| CN104825368A (en) * | 2015-05-26 | 2015-08-12 | 陈琳仁 | Natural plant active toothpaste and preparation method thereof |
| CN104905987A (en) * | 2015-05-29 | 2015-09-16 | 广州立白企业集团有限公司 | Child toothpaste composition |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105147583A (en) | 2015-12-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101955468B1 (en) | Preparing method for toothpaste composition comprising natural extracts | |
| US8435499B2 (en) | Toothpowder composition containing wheat flour and bamboo salt | |
| KR102251288B1 (en) | Cosmetic composition for improving blood circulation, including cissus and spring onion fermented extract | |
| JP4246736B2 (en) | Composition for oral dental treatment of medicinal herbs and preparation method thereof | |
| KR20120133799A (en) | Functional soap and manufacturing method of it | |
| CN105147583B (en) | A kind of children special-purpose toothpaste containing Sasanguasaponin and preparation method thereof | |
| KR102004366B1 (en) | A cosmetic composition comprising centipeda minima extract | |
| US10434057B2 (en) | Cosmetic composition comprising osmanthus asiaticus extract and clematis apiifolia extract | |
| KR101782858B1 (en) | Toothpaste composition comprising of medicinal plants | |
| JP5087686B2 (en) | Hair growth / hair growth agent | |
| JP4472404B2 (en) | Oral solid composition | |
| KR100357416B1 (en) | Compositions of whitening cosmetics containing special herbal extracts | |
| KR101926080B1 (en) | Soap composition and soap comprising the same | |
| CN107737083A (en) | A kind of children's toothpaste and preparation method thereof | |
| KR102405338B1 (en) | Toothpaste composition containing the fragrance fermented extract and method for producing same | |
| KR101599767B1 (en) | A toothpaste composition comprising non-toxic mineral sulfur and a method for preparation thereof | |
| KR101978742B1 (en) | Composition for improving sleep comprising natural herbal medicine materials | |
| KR20170138709A (en) | A soap composition for traditional oriental | |
| KR101243530B1 (en) | Hair Cosmetic Composition for Growth Promotion of Hairs Containing Extracted Concentrated Solution From Pine Leaves | |
| KR102520908B1 (en) | Preparation of aged solution of fruit of dioscorea opposita thumb, and aged solution of fruit of dioscorea opposita thumb prepared thereby | |
| KR102061610B1 (en) | Oral cleansing composition containing peppermint oil | |
| CN108066208A (en) | It is a kind of containing smearing the composition of tea and plant extracts to skin cleaning action | |
| CN108354872A (en) | A kind of Chinese medicinal toothpaste and preparation method thereof | |
| KR20140115228A (en) | Composition for prevention or treatment of hair loss comprising oriental herbal extracts | |
| CN109419948A (en) | A kind of Chinese medicine tooth-protective chewing gum and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |