CN104905987A - Child toothpaste composition - Google Patents
Child toothpaste composition Download PDFInfo
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- CN104905987A CN104905987A CN201510288900.5A CN201510288900A CN104905987A CN 104905987 A CN104905987 A CN 104905987A CN 201510288900 A CN201510288900 A CN 201510288900A CN 104905987 A CN104905987 A CN 104905987A
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Abstract
The invention discloses child toothpaste composition. The child toothpaste composition comprises, by weight, 0.1-5 percent of thickener, 0.5-4 percent of solubilizer, 1-60 percent of humectant, 10-90 percent of water, 0.1-2 percent of essence and the balance other components. Abrasives are not added into the child toothpaste composition, and toothpaste body is transparent, generates a little or nearly no foam, is easy to extrude and brush, so that friction to the surfaces of teeth is reduced. The child toothpaste composition is high in safety with the pH range being 5.5-7.5, and can be used as training toothpaste for children at the age of 2-6.
Description
Technical field
The present invention relates to oral care product technical field, particularly relate to a kind of without abrasivus, low bubble or non-foam, swallow harmless children's toothpaste compositions.
Background technology
Ordinary toothpaste generally all contains abrasivus, thickening agent, wetting agent, foaming agent, essence, water and other composition from formula angle.By the friction of abrasivus and dental surface, reach the effect of removing dental surface dental plaque, DNA exogenous pigment spot.The foam of ordinary toothpaste needs to enrich very much to reach clean effect and desirable mouthfeel usually.
2-6 year Pediatric Oral Emergency grow be in stage milk teeth period, child's feature of brushing teeth in this stage is: control ability is poor, and process of brushing teeth easily is swallowed; Oral environment is tender and lovely, stimulates toleration weak; Brush teeth firmly little, mastic is not easy brush and opens.And child brushes teeth in process at use tooth paste product, can swallow some toothpaste unavoidably, eating for a long time can negative unhealthy.
For above feature, the children's toothpaste product of prior art mainly focuses on the exploitation of the functional tooth paste products such as mothproof, few zest, but result of use is still undesirable, also requires further improvement its recipe ingredient.
Summary of the invention
The object of the invention is to, overcome the defect that existing children's toothpaste product exists, and a kind of new children's toothpaste compositions is provided, not containing abrasivus and foaming agent in its formula, zest is low, and mastic yield stress is little, easy brush is opened, not fluorine-containing, even if swallow also harmless health in process of brushing teeth, be suitable as children training toothpaste.
The object of the invention to solve the technical problems realizes by the following technical solutions.According to a kind of children's toothpaste compositions that the present invention proposes, by weight percentage, the wetting agent of the thickening agent containing 0.1-5%, the solubilizing agent of 0.5-4%, 1-60%, the water of 10-90%, the essence of 0.1-2%, surplus is other components.
Preferably, children's toothpaste compositions of the present invention, by weight percentage, the wetting agent of the thickening agent containing 0.1-3%, the solubilizing agent of 1-3%, 10-60%, the water of 10-90%, the essence of 0.1-1%, surplus is other components.
Children's toothpaste compositions of the present invention is not added as abrasivuss such as calcium carbonate, silicon dioxide, calcium hydrogen phosphate, aluminium oxidies; And not containing the surfactant of laurilsulfate sodium, cocamido propyl betaine, the contour foam of sodium lauroyl sarcosine.
Children's toothpaste compositions of the present invention, the mixture of one or more in described thickening agent preferred cellulose glue, sodium polyacrylate, carrageenan and xanthan gum.
Children's toothpaste compositions of the present invention, one or several mixture in the preferred polyoxyethylene ether castor oil hydrogenated of described solubilizing agent, poloxamer, tween, span.
Children's toothpaste compositions of the present invention, one or more mixture of the preferred sorbitol of described wetting agent, glycerol, propylene glycol and Polyethylene Glycol.
Children's toothpaste compositions of the present invention, other toothpaste components described comprise antiseptic, supplementary, pigment, sweeting agent etc.In addition, antiseptic of the present invention can be sodium benzoate, potassium sorbate, benzyl alcohol, Nipagin ester etc.; Supplementary of the present invention can be vitamin C derivatives, vitamin e derivative or mineral; Pigment preferred food product level color element; Sweeting agent can be saccharin sodium, sucralose, Momordia grosvenori aglycone etc.
Children's toothpaste compositions of the present invention, its pH scope is between 5.5-7.5.
Children's toothpaste compositions of the present invention, it can be prepared by the following two kinds different process method.
A production technology for children's toothpaste product compounding system containing acrylic acid polymer, comprises following processing step:
1) add deionized water, water-soluble substances (sweeting agent, pigment etc.) etc., be stirred to and dissolve completely;
2) opening under the condition stirred, slowly adding acrylic acid polymer, being stirred to evenly;
3) if also containing other thickening agents, with glycerol or mixed with propylene glycol, be stirred to evenly and add step 2) in;
4) add the wetting agent of surplus, solubilizing agent, essence successively, open vacuum, be stirred to evenly;
5) add nertralizer, stir, open vacuum;
6) degassed, fill after the assay was approved;
In addition, a kind of not containing the production technology of the children's toothpaste product compounding system of acrylic acid polymer, comprise following processing step:
1) add the wetting agents such as deionized water, water-soluble substances (sweeting agent, pigment etc.), sorbitol, be stirred to and dissolve completely;
2) after propylene glycol or glycerol mix with thickening agent, stir, add step 1) in, continue to be stirred to evenly;
3) add solubilizing agent, essence successively, open vacuum, be stirred to evenly;
4) degassed, fill after the assay was approved.
By technique scheme, children's toothpaste compositions tool of the present invention has the following advantages and beneficial effect:
1) technology disclosed by the invention is different from prior art, not containing abrasivus in formula, and mastic transparent (even if also can keep transparent at low temperatures), mastic has pseudoplastic behavior and thixotropy, yield stress is little, can stand on toothbrush and not sink simultaneously, recipe ingredient safety be high, and immediately swallowing in the process of brushing teeth does not have toxic and side effects yet.
2) not containing the formulation of tooth-paste system of abrasivus, pasty consistence and mastic transparency often can not be taken into account, if pasty consistence is enough large, but transparency is often inadequate, and mastic is coarse rough; Not containing abrasivus, the few or almost non-foam of mastic transparent foaming, and there is the excellent rheological properties of toothpaste, have certain denseness, mastic is easily extruded, and easily brush is opened, and reduces the friction to dental surface, pH scope 5.5-7.5.
3) selection of the raw material components of tooth paste product of the present invention considers the safety of raw material, prioritizing selection food grade materials, and final products are tested through oral cavity toxicology.The toothpaste of above-mentioned characteristic can be used as 2-6 year the child training toothpaste that uses.
Accompanying drawing explanation
Fig. 1 display be embodiment of the present invention 1-4 and comparative example 1-3 yield stress contrast.
Detailed description of the invention
Below by way of concrete preferred embodiment in conjunction with effect test example content, the present invention is expressed in further detail, but the present invention is not limited in following embodiment.
The invention discloses a kind of children's toothpaste compositions not containing abrasivus, mastic transparent (even if also can keep transparent at low temperatures), the few or almost non-foam of foam, mastic is easily extruded, and easily brush is opened, and reduce the friction to dental surface, safety is high; And have the rheological properties that toothpaste is excellent, have certain denseness, can stand on toothbrush and not sink, mastic be easily extruded, easily brush is opened, and reduces the friction to dental surface, pH scope 5.5-7.5.
Dentifrice composition of the present invention does not add abrasivus, as: calcium carbonate, silicon dioxide, calcium hydrogen phosphate, aluminium oxide etc., containing percentage by weight 0.1-5% thickening agent, percentage by weight 0.5-4% solubilizing agent, percentage by weight 1-60% wetting agent, percentage by weight 10-90% water, percentage by weight 0.1-2% essence and other toothpaste components.And not containing fizzy surfactants such as laurilsulfate sodium, cocamido propyl betaine, sodium lauroyl sarcosines.
RH40 in following examples refers to polyoxyethylene ether castor oil hydrogenated; F127 refers to oxirane and propylene oxide block copolymer.
embodiment 1
A kind of children's toothpaste compositions, it is made up of following raw material components:
The preparation method technique of the embodiment of the present invention 1 can be expressed as follows:
Add deionized water, xylitol, vitamin C phosphoric ester, be stirred to and dissolve completely; Opening under the condition stirred, evenly adding sodium polyacrylate, being stirred to evenly; Add glycerol, sorbitol, Vitamin E acetate, RH40, essence successively, open vacuum, be stirred to evenly; Add sodium hydroxide neutralization, stir, open vacuum; Degassed, fill after the assay was approved.
embodiment 2
A kind of children's toothpaste compositions, it is made up of following raw material components:
The preparation method technique of the embodiment of the present invention 2 can be expressed as follows:
Add deionized water, sodium benzoate, vitamin C phosphoric ester, xylitol etc., be stirred to and dissolve completely; Opening under the condition stirred, evenly adding sodium polyacrylate, being stirred to evenly; Add Vitamin E acetate, sorbitol, glycerol, F127, essence successively, open vacuum, be stirred to evenly; Add sodium hydroxide neutralization, stir, open vacuum; Degassed, fill after the assay was approved.
embodiment 3
A kind of children's toothpaste compositions, it is made up of following raw material components:
The preparation method technique of the embodiment of the present invention 3 can be expressed as follows:
Add deionized water, sodium benzoate, xylitol, vitamin C phosphoric ester, sodium bicarbonate, be stirred to and dissolve completely; After CMC is mixed homogeneously with glycerol, join in deionized water, be stirred to evenly; Add Vitamin E acetate, sorbitol, RH40, essence successively, open vacuum, be stirred to evenly; Degassed, fill after the assay was approved.
comparative example 1-3
The raw material components composition of table 1 comparative example 1-3
The preparation method technique of comparative example 1-3 of the present invention can be expressed as follows:
1) add deionized water, water-soluble substances, be stirred to and dissolve completely;
2) add wetting agent glycerol, sorbitol, Polyethylene Glycol-12, be stirred to evenly;
3) add hydrated silica, CMC, after mixing, add step 2) in, continue to be stirred to evenly;
4) add sodium lauryl sulfate, essence successively, open vacuum, be stirred to evenly; Degassed, fill after the assay was approved.
effect test example
1, dentin abrasion is tested
This test is with reference to ISO11609-2010Annex B.
Table 2 dentin abrasion test result
| Sample | Dentin abrasion (RDA) |
| Embodiment 1 | 14.6 |
| Embodiment 2 | 13.4 |
| Embodiment 3 | 14.1 |
| Comparative example 1 | 103.9 |
| Comparative example 2 | 110.2 |
| Comparative example 3 | 84.1 |
As can be seen from Table 2, the dentin abrasion value of embodiments of the invention 1-3 is significantly lower than comparative example.And all not containing abrasivus in embodiment 1-3, the dentin abrasion shown may cause dentin abrasion due to toothbrush.
2, mastic yield stress test
Can find out by Fig. 1, the yield stress of embodiment 1-3 is significantly lower than comparative example 1-3.Yield stress is less, illustrates more easily to flow under certain shear stress, scrubs dispersibility better, easilier extrudes from dentifrice tube.
3, chmice acute per os toxicity test
This test is with reference to " cosmetics health specification " 2007 editions
Testing environment: SPF level Animal House; Room temperature 22 ± 1 DEG C, humidity 60 ± 5%.
Laboratory animal: 10 SPF level kunming mices (5 male and 5 female), body weight 18-20 gram.
Sample treatment: take embodiment 125.0g sample and add ultra-pure water mixing to 100ml, as experiment liquid.
Experimental procedure:
1) dosage: during prerun, does not find that 5000mg/kg body weight dose occurs dead, therefore formal test design dosage is 5000mg/kg body weight;
2) contaminate: give test liquid by the amount per os gavage of 0.2%ml/10g body weight, before gavage, animal fasting 16 hours, freely drinks water.Normal diet is given after gavage;
3) observe: laboratory observation 14 days, record poisoning symptom and death condition every day, calculate LD50.
Experimental result:
In 14 day observation period, all animal subjects have no obvious poisoning symptom and death.Therefore its mouse oral acute LD 50 >5000mg/kg.
Table 3 tested material is to chmice acute Oral toxicity result of the test
As can be seen from the result of table 3, chmice acute Oral toxicity result of the test shows, and embodiment 1 is actual nontoxic level, and hint is swallowed harmless.
The above, it is only preferred embodiment of the present invention, not any pro forma restriction is done to the present invention, therefore everyly do not depart from technical solution of the present invention content, the any simple modification done above embodiment according to technical spirit of the present invention, equivalent variations and modification, all still belong in the scope of technical solution of the present invention.
Claims (7)
1. a children's toothpaste compositions, is characterized in that, it comprises each raw material components of following percentage by weight:
2. children's toothpaste compositions according to claim 1, is characterized in that, it comprises each raw material components of following percentage by weight:
3. children's toothpaste compositions according to claim 1 and 2, is characterized in that: described thickening agent is selected from the mixture of one or more in cellulose gum, sodium polyacrylate, carrageenan and xanthan gum.
4. children's toothpaste compositions according to claim 1 and 2, is characterized in that: described solubilizing agent is selected from the mixing of one or more in polyoxyethylene ether castor oil hydrogenated, poloxamer, tween, span.
5. children's toothpaste compositions according to claim 1 and 2, is characterized in that: described wetting agent is selected from the mixture of one or more in sorbitol, glycerol, propylene glycol, Polyethylene Glycol.
6. children's toothpaste compositions according to claim 1 and 2, is characterized in that: other components described comprise the mixture of one or more in antiseptic, supplementary, pigment, sweeting agent.
7. children's toothpaste compositions according to claim 1 and 2, is characterized in that: its pH scope of described children's toothpaste compositions is between 5.5-7.5.
Priority Applications (1)
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| CN201510288900.5A CN104905987B (en) | 2015-05-29 | 2015-05-29 | A kind of children's toothpaste composition |
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| CN201510288900.5A CN104905987B (en) | 2015-05-29 | 2015-05-29 | A kind of children's toothpaste composition |
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| CN104905987B CN104905987B (en) | 2017-11-21 |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147583A (en) * | 2015-09-30 | 2015-12-16 | 福建春辉生物工程有限公司 | Special camellia-saponin-contained toothpaste for child and preparation method thereof |
| CN106214591A (en) * | 2016-09-07 | 2016-12-14 | 马鞍山纽盟知识产权管理服务有限公司 | A kind of children special-purpose high-efficiency tooth paste |
| CN106236610A (en) * | 2016-08-17 | 2016-12-21 | 林少英 | A kind of toothpaste |
| CN106606455A (en) * | 2017-01-22 | 2017-05-03 | 福建农林大学 | Konjac glucomannan child toothpaste and preparation method thereof |
| CN108685719A (en) * | 2018-07-16 | 2018-10-23 | 纳爱斯集团有限公司 | Deaerate composition and application thereof and floride-free transparent children's toothpaste and preparation method thereof |
| WO2018221837A1 (en) * | 2017-05-31 | 2018-12-06 | 주식회사 엘지생활건강 | Pumping type toothpaste composition |
| CN114028273A (en) * | 2021-12-03 | 2022-02-11 | 广州立白企业集团有限公司 | Tooth cleaning composition |
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147583A (en) * | 2015-09-30 | 2015-12-16 | 福建春辉生物工程有限公司 | Special camellia-saponin-contained toothpaste for child and preparation method thereof |
| CN105147583B (en) * | 2015-09-30 | 2018-01-02 | 福建春辉生物工程有限公司 | A kind of children special-purpose toothpaste containing Sasanguasaponin and preparation method thereof |
| CN106236610A (en) * | 2016-08-17 | 2016-12-21 | 林少英 | A kind of toothpaste |
| CN106214591A (en) * | 2016-09-07 | 2016-12-14 | 马鞍山纽盟知识产权管理服务有限公司 | A kind of children special-purpose high-efficiency tooth paste |
| CN106606455A (en) * | 2017-01-22 | 2017-05-03 | 福建农林大学 | Konjac glucomannan child toothpaste and preparation method thereof |
| WO2018221837A1 (en) * | 2017-05-31 | 2018-12-06 | 주식회사 엘지생활건강 | Pumping type toothpaste composition |
| CN110709049A (en) * | 2017-05-31 | 2020-01-17 | 株式会社Lg生活健康 | Pump type toothpaste composition |
| EP3632405A4 (en) * | 2017-05-31 | 2021-03-10 | LG Household & Health Care Ltd. | Pumping type toothpaste composition |
| US11771642B2 (en) | 2017-05-31 | 2023-10-03 | Lg Household & Health Care Ltd. | Pumping type toothpaste composition |
| CN108685719A (en) * | 2018-07-16 | 2018-10-23 | 纳爱斯集团有限公司 | Deaerate composition and application thereof and floride-free transparent children's toothpaste and preparation method thereof |
| CN108685719B (en) * | 2018-07-16 | 2020-05-26 | 纳爱斯集团有限公司 | Degassing composition and application thereof, fluoride-free transparent children toothpaste and preparation method thereof |
| CN114028273A (en) * | 2021-12-03 | 2022-02-11 | 广州立白企业集团有限公司 | Tooth cleaning composition |
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