JP3854715B2 - Dentifrice composition - Google Patents
Dentifrice composition Download PDFInfo
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- JP3854715B2 JP3854715B2 JP08176298A JP8176298A JP3854715B2 JP 3854715 B2 JP3854715 B2 JP 3854715B2 JP 08176298 A JP08176298 A JP 08176298A JP 8176298 A JP8176298 A JP 8176298A JP 3854715 B2 JP3854715 B2 JP 3854715B2
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- dentifrice composition
- dentifrice
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- silicic acid
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Description
【０００１】
【発明の属する技術分野】
本発明は歯磨剤組成物に関し、さらに詳しくは、経時的な変色が抑制され安定性に優れたプロポリスエキス含有歯磨剤組成物に関する。
【０００２】
【従来の技術】
プロポリスとは、ミツバチが種々の植物から採取してきた樹脂状物で巣箱内に貯蔵される。古くからその薬効作用が注目されて民間薬として繁用されており、今日においても、歯磨剤組成物、化粧品、健康食品等に応用され実用化されている。しかしながら、従来のプロポリスエキス含有歯磨剤組成物は、経時的に、しばしば茶褐色に着色する場合があり、特に高温保存時において変色が起こりやすいという欠点がある。このようなプロポリスエキス含有歯磨剤組成物の変色の原因はプロポリスエキス自体の変色によるものと考えられる。
【０００３】
【発明が解決しようとする課題】
本発明の目的は、プロポリスエキスを含有しながらも、経時的に変色の少ない歯磨剤組成物を提供することにある。
【０００４】
【課題を解決するための手段】
本発明者らは上記目的を達成するために鋭意研究を重ねた結果、プロポリスエキスを含有する歯磨剤組成物において、含水ケイ酸及び無水ケイ酸のいずれか一方、もしくは両方を含有させることによって、プロポリスエキスの効果を減じることなく経時的に変色の少ない歯磨剤組成物が得られることを見いだし、本発明を完成させるにいたった。
従って本発明は、プロポリスエキスを含有する歯磨剤組成物であって、含水ケイ酸及び無水ケイ酸からなる群から選ばれる少なくとも１種を含有することを特徴とする歯磨剤組成物に関する。
【０００５】
本発明の歯磨剤組成物は、その形態は特に限定されるものではないが、練り歯磨剤、潤製歯磨剤、粉歯磨剤、液状歯磨剤、液体歯磨剤、水歯磨剤、洗口剤などの各種形態がある。
本発明の歯磨剤組成物に使用するプロポリスエキスとは、ミツバチ科ミツバチ（Apis mellifera L., Apis indica RODOSZKOWSKI)の巣及び巣箱から得られるヤニ状物質であるプロポリスの抽出液で、主成分はフラボノイドである。通常アルコール、特にエタノールの抽出液が知られており、それらは市場で一般に入手することができる。本発明においては、そのような市販品を使用することができる。
本発明の歯磨剤組成物に使用するプロポリスエキスの配合量は、特に制限されるものではないが、歯磨剤組成物の全重量に基づいて0.０１〜１0.０重量％が適当であり、特に1.０〜5.０重量％とすることが好ましい。
【０００６】
本発明の歯磨剤組成物に使用する含水ケイ酸及び無水ケイ酸とは、通常歯磨剤組成物の中に使用されているものが使用でき、それらは市場で一般に入手することができる。本発明においては、そのような市販品を使用することができる。
含水ケイ酸も無水ケイ酸も歯磨剤組成物における研磨剤として知られているが、これらはプロポリスエキス含有歯磨剤組成物において変色を抑制する安定剤として効果を発揮する。
【０００７】
本発明の歯磨剤組成物には、含水ケイ酸及び無水ケイ酸のいずれか一方、もしくは双方を併用する。これらの歯磨剤組成物における配合量は、歯磨剤組成物の全重量に基づいて全体の0.１〜４0.０重量％が可能であるが、安定剤としては1.０〜３0.０重量％が適当であり、より好ましくは5.０〜２0.０重量％である。
これらの配合量が0.１重量％未満であると、変色を抑制する効果が十分に発揮されず、一方４0.０重量％を超えても安定剤としての作用効果の向上が見られない。
含水ケイ酸及び無水ケイ酸を併用することが特に望ましく、その際の含水ケイ酸と無水ケイ酸の重量比は１：１〜１：１０が適当である。
【０００８】
本発明の歯磨剤組成物は、歯磨剤組成物に通常使用される添加剤、例えば研磨剤、潤滑剤、増粘剤、発泡剤、可溶化剤、甘味剤、色素、溶剤、防腐剤及び各種有効成分等を含有することができる。それらの配合量は、通常使用される量でよい。これらの成分の具体例を下記に示す。
研磨剤；リン酸水素カルシウム、水酸化アルミニウム、ピロリン酸カルシウム、炭酸カルシウム等。
湿潤剤；グリセリン、ソルビトール、プロピレングリコール、ジプロピレングリコール、１，３−ブチレングリコール、ポリエチレングリコール、キシリトール、マルチトール等。
増粘剤；カラギーナン、カルボキシメチルセルロースナトリウム、メチルセルロース、ヒドロキシエチルセルロース、アルギン酸ナトリウム、キサンタンガム、ポリアクリル酸ナトリウム、カルボキシビニルポリマー等。
発泡剤；ラウリル硫酸ナトリウム、Ｎ−ラウロイルサルコシンナトリウム、ヤシ油脂肪酸アミドプロピルベタイン液、２−アルキル−Ｎ−カルボキシメチル−Ｎ−ヒドロキシエチルイミダゾリニウムベタイン等。
【０００９】
可溶化剤；ポリオキシエチレン硬化ヒマシ油、ポリグリセリン脂肪酸エステル等。
防腐剤；パラオキシ安息香酸エステル、安息香酸ナトリウム、塩酸アルキルジアミノエチルグリシン等。
甘味剤；サッカリンナトリウム、ステビオサイド等。
溶剤；水、エタノール等。
その他の成分；酢酸トコフェロール、イソプロピルメチルフェノール、塩化ナトリウム、アラントイン、グリチルリチン酸及びその塩類、フッ化物、クロルヘキシジン類、エデト酸塩、銅クロロフィリンナトリウム等。
【００１０】
本発明の歯磨剤組成物は、常法に従って製造することができる。例えば練り歯磨剤であれば、含水ケイ酸及び無水ケイ酸のいずれか一方、もしくは双方とプロポリス、並びに通常用いられる歯磨組成物の成分とを攪拌機で混合攪拌した後、減圧脱泡することにより得られる。
また、本発明の歯磨剤組成物に使用する容器に特に制限はなく、通常用いることができるアルミニウムチューブ、ラミネートチューブ、プラスチックボトル等が使用できる。本発明の歯磨剤組成物はその適量をブラシにとり使用することができる。
【００１１】
【発明の効果】
本発明によれば、経時的な変色が抑制された安定性に優れたプロポリスエキス含有歯磨剤組成物が提供される。
【００１２】
以下、比較例と実施例により本発明をより詳細に説明するが、本発明はこれらに限定されるものではない。
【比較例１、２及び実施例１〜１６】
プロポリスエキスを含有する練り歯磨剤組成物を表１及び表２に示す組成（単位：重量％）で常法に従って製造した。なお、精製水は全量が１００重量％となるように適量添加した。
このように製造した歯磨剤組成物を、それぞれラミネートチューブ及びアルミチューブに充填し、５０℃で１ケ月保存し、製造直後のものと比較した際の着色度合について、官能評価を実施した。その結果を表１及び表２に併せて示す。試験の評価基準は下記のとおりである。
◎：ほとんど着色なし
○：やや着色あり
△：着色あり
×：非常に着色あり
【００１３】
【表１】
【表２】
【実施例１７〜２２】
練り歯磨剤組成物の調製
下記表３に示した組成（単位：重量％）で常法に従って製造した。なお、精製水は全量が１００重量％となるように適量添加した。
【００１６】
【表３】
【実施例２３】
液状歯磨剤組成物の調製
下記に示した組成（単位：重量％）で常法にしたがって製造した。なお、精製水は全量が１００重量％となるように適量添加した。
含水ケイ酸 １．０
無水ケイ酸 １０．０
カルボキシメチルセルロース １．０
グリセリン ２５．０
ソルビトール ５０．０
ポリオキシエチレン硬化ヒマシ油（60E.O.) ０．５
ラウリル硫酸ナトリウム １．０
プロポリスエキス ３．０
パラオキシ安息香酸エステル ０．１
香料 １．０
精製水 適量[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a dentifrice composition, and more particularly to a propolis extract-containing dentifrice composition that is superior in stability and is prevented from being discolored over time.
[0002]
[Prior art]
Propolis is a resinous material that bees have collected from various plants and is stored in the nest box. Its medicinal effects have been attracting attention for a long time, and it has been widely used as a folk medicine. Even today, it is applied and used in dentifrice compositions, cosmetics, health foods and the like. However, the conventional propolis extract-containing dentifrice composition often has a brown color over time, and has a disadvantage that discoloration is likely to occur particularly during high-temperature storage. The cause of discoloration of such a dentifrice composition containing a propolis extract is considered to be due to discoloration of the propolis extract itself.
[0003]
[Problems to be solved by the invention]
An object of the present invention is to provide a dentifrice composition that contains a propolis extract and has little discoloration over time.
[0004]
[Means for Solving the Problems]
As a result of intensive studies to achieve the above object, the inventors of the present invention have included a dentifrice composition containing a propolis extract, by containing one or both of hydrous silicic acid and silicic anhydride, It was found that a dentifrice composition with little discoloration over time could be obtained without reducing the effect of propolis extract, and the present invention was completed.
Therefore, the present invention relates to a dentifrice composition containing a propolis extract, which contains at least one selected from the group consisting of hydrous silicic acid and anhydrous silicic acid.
[0005]
The form of the dentifrice composition of the present invention is not particularly limited, but it is a toothpaste, a toothpaste, a toothpaste, a liquid dentifrice, a liquid dentifrice, a liquid dentifrice, a water dentifrice, a mouthwash, etc. There are various forms.
The propolis extract used in the dentifrice composition of the present invention is an extract of propolis which is a spider-like substance obtained from nests and nest boxes of Apis mellifera L., Apis indica RODOSZKOWSKI, the main component of which is a flavonoid It is. Usually extracts of alcohols, in particular ethanol, are known and are generally available on the market. In the present invention, such commercially available products can be used.
The blending amount of the propolis extract used in the dentifrice composition of the present invention is not particularly limited, but is suitably 0.01 to 10.0 wt% based on the total weight of the dentifrice composition, In particular, it is preferably 1.0 to 5.0% by weight.
[0006]
As the hydrous silicic acid and anhydrous silicic acid used in the dentifrice composition of the present invention, those usually used in dentifrice compositions can be used, and they are generally available on the market. In the present invention, such commercially available products can be used.
Both hydrous silicic acid and anhydrous silicic acid are known as abrasives in dentifrice compositions, and these are effective as stabilizers that suppress discoloration in propolis extract-containing dentifrice compositions.
[0007]
In the dentifrice composition of the present invention, either one of hydrous silicic acid and anhydrous silicic acid, or both are used in combination. The compounding amount in these dentifrice compositions can be 0.1 to 40.0% by weight based on the total weight of the dentifrice composition, but 1.0 to 30.0% as a stabilizer. % Is suitable, more preferably 5.0 to 20.0% by weight.
When the blending amount is less than 0.1% by weight, the effect of suppressing discoloration is not sufficiently exerted, and when it exceeds 40.0% by weight, the improvement of the action and effect as a stabilizer is not observed.
It is particularly desirable to use hydrous silicic acid and anhydrous silicic acid together, and the weight ratio of hydrous silicic acid to silicic anhydride is suitably 1: 1 to 1:10.
[0008]
The dentifrice composition of the present invention comprises additives usually used in dentifrice compositions, such as abrasives, lubricants, thickeners, foaming agents, solubilizers, sweeteners, dyes, solvents, preservatives, and various kinds. An active ingredient etc. can be contained. The compounding amount thereof may be a commonly used amount. Specific examples of these components are shown below.
Abrasive: calcium hydrogen phosphate, aluminum hydroxide, calcium pyrophosphate, calcium carbonate, etc.
Wetting agent; glycerin, sorbitol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, polyethylene glycol, xylitol, maltitol and the like.
Thickener: carrageenan, sodium carboxymethylcellulose, methylcellulose, hydroxyethylcellulose, sodium alginate, xanthan gum, sodium polyacrylate, carboxyvinyl polymer, etc.
Foaming agents; sodium lauryl sulfate, sodium N-lauroyl sarcosine, coconut oil fatty acid amidopropyl betaine solution, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine and the like.
[0009]
Solubilizer; polyoxyethylene hydrogenated castor oil, polyglycerin fatty acid ester, and the like.
Preservatives: paraoxybenzoic acid ester, sodium benzoate, alkyldiaminoethylglycine hydrochloride and the like.
Sweeteners; saccharin sodium, stevioside, etc.
Solvent: water, ethanol, etc.
Other ingredients: tocopherol acetate, isopropylmethylphenol, sodium chloride, allantoin, glycyrrhizic acid and its salts, fluoride, chlorhexidine, edetate, copper chlorophyllin sodium, etc.
[0010]
The dentifrice composition of the present invention can be produced according to a conventional method. For example, if it is a toothpaste, it is obtained by mixing and stirring one or both of hydrous silicic acid and silicic anhydride with propolis and the components of a commonly used dentifrice composition, followed by degassing under reduced pressure. It is done.
Moreover, there is no restriction | limiting in particular in the container used for the dentifrice composition of this invention, The aluminum tube which can be used normally, a laminate tube, a plastic bottle, etc. can be used. An appropriate amount of the dentifrice composition of the present invention can be used in a brush.
[0011]
【The invention's effect】
ADVANTAGE OF THE INVENTION According to this invention, the propolis extract containing dentifrice composition excellent in stability in which the discoloration with time was suppressed was provided.
[0012]
Hereinafter, although a comparative example and an example explain the present invention in detail, the present invention is not limited to these.
[Comparative Examples 1 and 2 and Examples 1 to 16]
A toothpaste composition containing a propolis extract was produced according to a conventional method with the compositions shown in Tables 1 and 2 (unit: wt%). Purified water was added in an appropriate amount so that the total amount was 100% by weight.
The dentifrice composition thus produced was filled in a laminate tube and an aluminum tube, respectively, stored at 50 ° C. for 1 month, and a sensory evaluation was performed on the degree of coloring when compared with that immediately after production. The results are also shown in Table 1 and Table 2. The evaluation criteria of the test are as follows.
A: Almost uncolored O: Slightly colored Δ: Colored x: Very colored [0013]
[Table 1]
[Table 2]
Examples 17 to 22
Preparation of toothpaste composition The composition (unit:% by weight) shown in Table 3 below was produced according to a conventional method. Purified water was added in an appropriate amount so that the total amount was 100% by weight.
[0016]
[Table 3]
Example 23
Preparation of liquid dentifrice composition The composition shown below (unit:% by weight) was produced according to a conventional method. Purified water was added in an appropriate amount so that the total amount was 100% by weight.
Hydrous silicate 1.0
Silica anhydride 10.0
Carboxymethylcellulose 1.0
Glycerin 25.0
Sorbitol 50.0
Polyoxyethylene hydrogenated castor oil (60E.O.) 0.5
Sodium lauryl sulfate 1.0
Propolis Extract 3.0
Paraoxybenzoic acid ester 0.1
Fragrance 1.0
Purified water
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP08176298A JP3854715B2 (en) | 1998-03-27 | 1998-03-27 | Dentifrice composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP08176298A JP3854715B2 (en) | 1998-03-27 | 1998-03-27 | Dentifrice composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11279038A JPH11279038A (en) | 1999-10-12 |
| JP3854715B2 true JP3854715B2 (en) | 2006-12-06 |
Family
ID=13755477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP08176298A Expired - Lifetime JP3854715B2 (en) | 1998-03-27 | 1998-03-27 | Dentifrice composition |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3854715B2 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4936587B2 (en) * | 2000-09-18 | 2012-05-23 | 有限会社ビオメディクス | Method for solubilizing propolis extract in water and water-soluble propolis composition |
| EP1566167B1 (en) * | 2002-11-07 | 2011-10-12 | Taisho Pharmaceutical Co., Ltd | Base for oral composition and oral composition |
| JP4712323B2 (en) * | 2004-07-08 | 2011-06-29 | 湧永製薬株式会社 | Oral composition |
| CN104721114A (en) * | 2015-01-28 | 2015-06-24 | 王进 | Borneol, beewax and gel type toothpaste and preparation method thereof |
-
1998
- 1998-03-27 JP JP08176298A patent/JP3854715B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11279038A (en) | 1999-10-12 |
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