CN105030592A - Qingyan Duzhong toothpaste and making method thereof - Google Patents
Qingyan Duzhong toothpaste and making method thereof Download PDFInfo
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Abstract
The invention discloses Qingyan Duzhong toothpaste which is made mainly by making bark of Eucommia, Drynaria rhizome, common Anemarrhena rhizome and halite into pharmaceutical ointment and mixing the pharmaceutical ointment with toothpaste substrate. The Qingyan Duzhong toothpaste has a tooth cleaning function and also has effects of tonifying kidney and strengthening teeth, nourishing yin to lessen fire and eliminating swelling to stop bleeding. The Qingyan Duzhong toothpaste is suitable for treating symptoms such as bad breath and gum redness and bleeding, has significant therapeutic effect and little side effect, is good for healthy growth of teeth and meets needs of people.
Description
Technical field
The present invention relates to a kind of toothpaste and preparation method thereof, particularly a kind of Halitum eucommia bark toothpaste and preparation method thereof.
Technical background
Periodontal disease is one of common oral disease, mainly comprises gingivitis and periodontitis.Gingivitis is the early symptom of periodontal disease, shows as red swelling of gingiva, hemorrhage, pain easily appears in gingiva when being rubbed and stimulate etc.If gingivitis can not get treating timely and effectively, serious periodontitis will be further development of.Periodontitis can make alveolar bone destruction, odontoseisis, and finally causing loss of tooth, is one of main reason causing absence of tooth.
Data according to the relevent statistics, the adult of China more than 90% suffers from periodontal disease in various degree, and almost periodontitis all occurred in various degree at it in life for everyone.Periodontal disease gives artificial one-tenth painful greatly, except the masticatory system function of infringement oral cavity, also can have a strong impact on the whole body health of human body.Modern medicine proves, periodontal disease can affect the function such as immune system, hormonal system of human body, and can bring out cardiovascular disease, diabetes, digestive tract disease, pulmonary infection etc.Therefore, periodontal disease is a kind of easily the ignorance by people but the very large oral disease of hazardness, can affect physical and mental health and the quality of life of human body.Depend merely on stomatological hospital and Drug therapy cannot meet people to improve the needs of oral health level, with the use of have these diseases of control oral cavity nursing health products, these diseases can progressively obtain effective prevention and corntrol.
Toothpaste is used from cleaning teeth with toothbrush one, and protection oral hygiene, is the indispensable oral cavity nursing health products of people's daily life, has very long history.Develop numerous toothpaste oral health being had to maintenance health-care effect successively at present, but make a general survey of existing tooth paste product, major part just plays the effect cleaned the teeth, and is difficult to the effect reaching the kidney invigorating teeth consolidating, nourishing YIN to lower pathogenic fire, detumescence hemostasis.Though some toothpaste can reach above-mentioned effect, curative effect is not obvious mostly, and small part is evident in efficacy, and people are large to the dependency of this part toothpaste, and side effect is large, is unfavorable for growing up healthy and sound of tooth, can not meet the needs of people.
Summary of the invention:
The object of the invention is to, a kind of Halitum eucommia bark toothpaste is provided.Described toothpaste has except having effect of cleaning the teeth, also has the kidney invigorating teeth consolidating, nourishing YIN to lower pathogenic fire, effect of detumescence hemostasis.Can be used for the diseases such as treatment halitosis, red swelling of gingiva be hemorrhage, evident in efficacy, side effect is little, is conducive to growing up healthy and sound of tooth, meets the needs of people.
For solving the problems of the technologies described above, the present invention realizes by the following technical solutions: a kind of Halitum eucommia bark toothpaste, calculate by weight, primarily of the drug extract that Cortex Eucommiae 1-20 part, Rhizoma Drynariae 1-20 part, Rhizoma Anemarrhenae 1-20 part and Halitum 1-20 part are first made, then be made with lotion of toothpaste substrate.
Aforesaid Halitum eucommia bark toothpaste, calculates by weight, primarily of the drug extract that Cortex Eucommiae 5-15 part, Rhizoma Drynariae 5-15 part, Rhizoma Anemarrhenae 5-15 part and Halitum 5-15 part are first made, then is made with lotion of toothpaste substrate.
Aforesaid Halitum eucommia bark toothpaste, calculates by weight, primarily of the Cortex Eucommiae 10 parts, Rhizoma Drynariae 10 parts, the Rhizoma Anemarrhenae 10 parts and Halitum 10 parts of drug extracts first made, then is made with lotion of toothpaste substrate.
Aforesaid Halitum eucommia bark toothpaste, calculate by weight, be made primarily of said medicine extractum 1.5-3 part, silicon dioxide 7-25 part, Polyethylene Glycol 8-28 part, glycerol 15-45 part, sodium carboxymethyl cellulose 0.5-1 part, xanthan gum 0.2-0.8 part, sodium lauryl sulfate 0.8-1.4 part, aluminium-magnesium silicate 0.5-1 part, sodium benzoate 0.1-0.3 part and saccharin sodium 0.2-0.8 part.
Aforesaid Halitum eucommia bark toothpaste, calculate by weight, be made primarily of said medicine extractum 2 parts, silica 14 parts, Polyethylene Glycol 16 parts, glycerol 30 parts, sodium carboxymethyl cellulose 0.8 part, xanthan gum 0.4 part, sodium lauryl sulfate 1.2 parts, aluminium-magnesium silicate 0.8 part, sodium benzoate 0.2 part and saccharin sodium 0.4 part.
Aforesaid Halitum eucommia bark toothpaste, such preparation of described drug extract: take the Cortex Eucommiae, Rhizoma Drynariae, the Rhizoma Anemarrhenae and Halitum by formula, adds 10 times amount soak by water 3 times, each 1.5h, filters, and merges decoction liquor, when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, obtains drug extract.
A manufacture method for aforesaid Halitum eucommia bark toothpaste, takes Polyethylene Glycol, glycerol, sodium carboxymethyl cellulose, xanthan gum, sodium benzoate and saccharin sodium by prescription and adds 3 times of water gagings, be heated to 40-50 DEG C, insulation is heated and stirred 1-2h also, obtained colloid solution, is cooled to 30 DEG C, for subsequent use; Said medicine extractum is added in colloid solution, stirs, then silicon dioxide and aluminium-magnesium silicate are slowly added in colloid solution successively, stirring and evenly mixing, then add sodium lauryl sulfate, stirring and evenly mixing, homogenizing, emulsifying, sterilizing, pack and get final product.
Toothpaste of the present invention first makes extractum by the Cortex Eucommiae, Rhizoma Drynariae, the Rhizoma Anemarrhenae and Halitum; Wherein, the Cortex Eucommiae (formal name used at school EucommiaulmoidesOliver) is Eucommiaceae plant.The medicinal Cortex Eucommiae, is the dry bark of the Eucommiaceae plant Cortex Eucommiae, is Chinese famous and precious tonic herb.Its sweet in the mouth, warm in nature.Can treat the lumbago and skelalgia or aching and limp unable that insufficiency of kidney-YANG causes, born of the same parents' tire that deficiency of liver-QI causes is not solid, the diseases such as scrotum pruritus due to damp pathogen.Be listed in top grade in Shennong's Herbal.The Cortex Eucommiae has invigorating the liver and kidney, and control spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, hypertension, antiabortive effect.The Cortex Eucommiae has regulating action in various degree to immune system, hormonal system, central nervous system, blood circulation and urinary system, the excited Pituitary Adrenalcortical system of Cortex Eucommiae energy, adrenal cortex reinforcing function.Shennong's Herbal: main pain along the spinal column, invigorating middle warmer benefit vital essence, hard muscles and bones, Qiang Zhi, except wet, dribbling urination of itching under the moon." property of medicine opinion ": control the cold buttocks lumbago of kidney, waist disease people is empty and stiffness of the body is straight, and wind also.Waist unfavorable adding and use it.Compendium of Material Medica: Cortex Eucommiae color is purple and moisten, and sweet in the mouth is micro-pungent, its temperature is put down, and Gan Wenneng mends, micro-pungent energy profit, therefore can enter liver and the kidney invigorating.Rhizoma Drynariae English name: Drynariafortunei.Polypodiales, Davalliaceae pteridophyta, the whole year all can excavate, removing silt, dry, or burns remove floss (scale) again.This product is flat strip, bends more, has branch, surface close by dark-brown to the ramentum of burgundy, soft as hair, through the fire person of burning in sepia or crineous, both sides and the protruding or recessed circular leaf scar of the equal tool of upper surface, minority have petiole residual base and fibrous root residual.Body is light, and matter is crisp, frangibility, section rufous, and vascular bundle is yellow point-like, arrangement ring formation.Odorless, lightly seasoned, micro-puckery.There is the kidney invigorating bone strengthening, continuous effect of hindering pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, the diseases such as vitiligo." property of medicine opinion ": " five kinds of over strain six types of severe debility disease, mouth (one do ' foot ') hands is not received, upper heat and lower cold for poison in main bone, wind blood pain." " Japan hanako materia medica ": " controls malignant boil, loses rotten meat, parasite killing." Rhizoma Anemarrhenae (Classification system: AnemarrhenaasphodeloidesBunge), herbaceos perennial, root stock, leaf to be grown thickly elongated lanceolar by base portion, and scape grows in leafage, uprightly cylindrical, total shape titbit, cluster, rawly becomes spike at top; Pollen is red, and lavender is to white; Fruit oblong, inside has most black seeds, flowering fruit bearing stage 6 ~ JIUYUE.Nature and flavor: bitter, cold.Gui Jing: enter lung, stomach, kidney channel.Function cures mainly: nourishing YIN to lower pathogenic fire, moisturizes laxation.Control dysphoria with smothery sensation to quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.For epidemic febrile disease, the lung excess of the stomach heat syndromes such as the high Sheng of pathogenic heat, high fever, excessive thirst, full and large pulse.The Rhizoma Anemarrhenae has the effect of clearing away heat-fire relieving restlessness.Collaborative effect is had, as Baihu Tang with Gypsum Fibrosum compatibility.For the card such as cough due to lung-heat or deficiency of YIN cough caused by dryness, expectorant is thick.This product has purte the white clearly, the effect of nourishing YIN and moistening the lung, and normal and Bulbus Fritillariae Uninbracteatae is same in order to removing heat from the lung and dissipating phlegm cough-relieving, and namely two is female loose.For hyperactivity of fire caused by deficiency of YIN, joint caused by lung deficiency of the kidney steams hectic fever, night sweat, the disease such as vexed.The Rhizoma Anemarrhenae has the effect of nourishing YIN to lower pathogenic fire.Normal is use with Cortex Phellodendri mutual reinforcement between, allocates in yin-nourishing drug, as ZHIBAI DIHUANG WAN.Can be used for the deficiency of YIN to quench one's thirst, disease sees thirsty, drinking water copiously, frequent micturition person.This product has YIN nourishing to moisten bath, promoting the production of body fluid to quench thirst effect.Same Radix Trichosanthis, Fructus Schisandrae Chinensis etc. with the use of heightening the effect of a treatment, as good wine soup.Clearing away heat-fire: for the hot excessive thirst of height, often join Gypsum Fibrosum; For cough due to lung-heat, often join Bulbus Fritillariae Uninbracteatae.Nourishing YIN to lower pathogenic fire: for heating, the night sweat of the deficiency of YIN, often join Cortex Phellodendri, Radix Rehmanniae." book on Chinese herbal medicine asks former ": control hemoptysis, breathe heavily, drenches, stomatosis, hematuria, singultus, night sweat, seminal emission, numbness flaccidity ， Chi Zong.Halitum is the salt of direct extraction from salt lake and be the salt of raw material at salt Tanaka dry in the sun with salt lake bittern.Salty in the mouth, cold in nature.Removing heat from blood, improving eyesight.Control hematuria, spit blood, radula is hemorrhage, conjunctival congestion with ophthalmalgia, the rotten string of wind-eye, toothache.Decoct soup or enter ball and fall apart; External is ground into powder and is wiped tooth or aquation is gargled, washed order.
Toothpaste of the present invention adopts said medicine first to make extractum, then is made with lotion of toothpaste substrate, and the sweet temperature of the Cortex Eucommiae in side, returns liver, kidney channel, have invigorating the liver and kidney, the effect of bone and muscle strengthening, for deficiency of the liver and kindey, and soreness of waist and knee joint, muscles and bones is unable, has a dizzy spell, hypertension is monarch drug; The bitter temperature of Rhizoma Drynariae, returns liver, kidney channel.Tool is cured the wound the merit of pain relieving, the kidney invigorating bone strengthening, and for lumbago due to renal deficiency, muscles and bones flaccidity is soft, Hiccough and deaf, and odontoseisis is ministerial drug, increases effect of the kidney invigorating teeth consolidating of the monarch drug Cortex Eucommiae; The Rhizoma Anemarrhenae is bitter sweet cold.Return lung, stomach, kidney channel.Clearing away heat-fire, nourshing Yin and drynsessmoistening prescription is adjuvant drug, and assistant helps the effect of the enriching yin and nourishing kidney of the Cortex Eucommiae and Rhizoma Drynariae, and help the dry using warming therapy of the Cortex Eucommiae processed and Rhizoma Drynariae, anti-temperature compensation is too; Halitum is salty-cold, GUIXIN, kidney, urinary bladder channel, tool heat clearing away, removing heat from blood, and the merit of improving eyesight is hemorrhage for gingival swelling and pain, strengthens monarch drug therapeutical effect, and Halitum the Cortex Eucommiae and Rhizoma Anemarrhenae priming can enter kidney for making medicine in help side simultaneously.Four taste Chinese medicines all return kidney channel, and the traditional Chinese medical science thinks the main tooth of kidney governing bones, and odontoseisis is derived from suffers from a deficiency of the kidney, and four medicine compatibilities are played altogether: effect of the kidney invigorating teeth consolidating, nourishing YIN to lower pathogenic fire, detumescence hemostasis.
Applicant carried out following experiments, provable the present invention has effective effect;
Experimental example effect experiment
One, hemostasis experiment
1 experiment material
1.1 experiment examination things
Toothpaste of the present invention (making by embodiment 1), YUNNAN BAIYAOFEN, Yunnan Paiyao Group Corp., Ltd produces, the accurate word Z53020798 of traditional Chinese medicines, lot number: 201106026.Medical starch, Guangdong, Guangdong De Feng starch sugar industry company limited starch factory is produced, lot number: 20110316.Toothpaste bare substrate sample, identical with test group toothpaste matrix, not containing any effect medicine.
1.2 laboratory animal
Healthy white rabbit 40, body weight 2.0-2.5kg; Thered is provided by Guiyang College of Traditional Chinese Medicine.
2 experimental techniques
Get healthy white rabbit 40, body weight 2.0 ~ 2.5kg, male and female dual-purpose.Slowly inject with 3% pentobarbital sodium 30mg/kg auricular vein, after family's rabbit anesthesia, lie on the back and be fixed on operating-table, abdominal part median incision is about 6 ~ 8cm, exposes and fixes liver, cuts liver organization be about 1cm with operating scissors at leftlobe of liver, wide about 1cm, height is 1cm about, and wound surface is hemorrhage in spraying sample.After wiping the blood of ejection, treat examination matter sample 1g at wound surface local spreading immediately, gauze is topped, to remove counterweight after the compressing of 200g counterweight 1min, 1min, observes haemostatic effect, with not hemorrhage for hemostasis.As still hemorrhage, then add spreading and continue pressurization after examination matter sample.1 time is observed, record bleeding stopping period every 30s.As still hemorrhage more than 3min, be then designated as and fail to stop blooding, bleeding stopping period is designated as > 3min.After each sample test, wash away residual tested material with 37 DEG C of normal saline, make wound surface again hemorrhage, then test next tested material sample.Every rabbit carries out 4 liver local woanded surface damage hemostasis test experiments, and the drug of topical application of Latin square program pressed by each tested material sample, to reduce the impact of liver local woanded surface damage otch difference and medication order.Each tested material sample amounts to the hemostasis experiment carrying out 20 rabbit liver local woanded surface bleeding due to traumies.Haemostatic effect is designated as score value F by scoring method reciprocal (10/T), and more than 3min fails to stop blooding, and F is designated as 0 without score value.
3 experimental results
Tested each sample carries out the hemostasis experimental result of rabbit liver local woanded surface bleeding due to trauma in table 1, records and checks according to statistics t.
The haemostatic effect (X ± S) of table 1 pair rabbit liver local woanded surface bleeding due to trauma
Note: compare with starch group: ##P < 0.01, ▲ P > 0.05; Compare with toothpaste bare substrate group: * * * P < 0.001.
4 results
As shown in Table 1, of the present invention group and YUNNAN BAIYAO group all have obvious haemostatic effect to rabbit liver local woanded surface bleeding due to trauma; Compare with toothpaste bare substrate group, all have significant difference, meaningful statistically; Test group toothpaste compares with YUNNAN BAIYAO group, and both do not have obvious diversity.Show that of the present invention group of toothpaste has obvious anastalsis.
Two, anti-rat paw edema test
Rat 50,200 ~ 250g, male and female half and half, be divided at random of the present invention group, fluocinonide group (0.025% ointment), matched group (giving equivalent substrate).Every Mus smears administration 1 time prior to metapedes, in right back whole lame subcutaneous injection 1% carrageenin 0.1ml after 15min, smears medicine to immediately right back foot.Measure whole lame girth after about every Mus respectively at after administration 1,2,3,4 hour, using two sufficient girth differences as swelling, smear medicine to again respectively after each measurement Rat Right metapedes.
Result: after medicine 2,3,4 hours toothpaste of the present invention (being prepared by embodiment 1) have obvious inhibitory action to rat paw edema, compare with matched group, p < 0.05.In table 2.
Table 2 is on the impact of rat paw edema
Note: compare with matched group, * P < 0.05**P < 0.01***P < 0.001
As shown in Table 2, toothpaste of the present invention has the effect of detumescence.
Below in conjunction with embodiment, invention is further described, but not as the foundation limited the present invention.
Detailed description of the invention:
Embodiment 1.
Formula: drug extract 2g, silica 1 4g, Polyethylene Glycol 16g, glycerol 30g, sodium carboxymethyl cellulose 0.8g, xanthan gum 0.4g, sodium lauryl sulfate 1.2g, aluminium-magnesium silicate 0.8g, sodium benzoate 0.2g and saccharin sodium 0.4g, Mint Essence 1.2g.
Extractum formula: Cortex Eucommiae 10g, Rhizoma Drynariae 10g, Rhizoma Anemarrhenae 10g and Halitum 2.5g.
Technique:
The preparation of drug extract: take the Cortex Eucommiae, Rhizoma Drynariae, the Rhizoma Anemarrhenae and Halitum by formula, adds 10 times amount soak by water 3 times, each 1.5h, filters, and merges decoction liquor, and when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, obtains drug extract.
The making of toothpaste: take Polyethylene Glycol, glycerol, sodium carboxymethyl cellulose, xanthan gum, sodium benzoate and saccharin sodium by prescription and add 3 times of water gagings, be heated to 40-50 DEG C, insulation is heated and stirred 1-2h also, and obtained colloid solution, is cooled to 30 DEG C, for subsequent use; Said medicine extractum is added in colloid solution, stirs, then silicon dioxide and aluminium-magnesium silicate are once slowly added in colloid solution, stirring and evenly mixing, then add sodium lauryl sulfate, stirring and evenly mixing, homogenizing, emulsifying, make 100g, sterilizing, pack and get final product.
Usage and dosage: each 1-2g, every day 2 times.
Embodiment 2.
Formula: drug extract 3g, silicon dioxide 25g, Polyethylene Glycol 28g, glycerol 45g, sodium carboxymethyl cellulose 1g, xanthan gum 0.8g, sodium lauryl sulfate 1.4g, aluminium-magnesium silicate 1g, sodium benzoate 0.3g, saccharin sodium 0.8g, Mint Essence 1.2g.
Extractum formula: Cortex Eucommiae 15g, Rhizoma Drynariae 15g, Rhizoma Anemarrhenae 15g and Halitum 3g.
Technique:
The preparation of drug extract: take the Cortex Eucommiae, Rhizoma Drynariae, the Rhizoma Anemarrhenae and Halitum by formula, adds 10 times amount soak by water 3 times, each 1.5h, filters, and merges decoction liquor, and when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, obtains drug extract.
The making of toothpaste: take Polyethylene Glycol, glycerol, sodium carboxymethyl cellulose, xanthan gum, sodium benzoate and saccharin sodium by prescription and add 3 times of water gagings, be heated to 40-50 DEG C, insulation is heated and stirred 1-2h also, and obtained colloid solution, is cooled to 30 DEG C, for subsequent use; Said medicine extractum is added in colloid solution, stirs, then silicon dioxide and aluminium-magnesium silicate are once slowly added in colloid solution, stirring and evenly mixing, then add sodium lauryl sulfate, stirring and evenly mixing, homogenizing, emulsifying, sterilizing, pack and get final product.
Usage and dosage: each 1-2g, every day 2 times.
Embodiment 3.
Formula: drug extract 1.5g, silicon dioxide 7g, Polyethylene Glycol 8g, glycerol 15g, sodium carboxymethyl cellulose 0.5g, xanthan gum 0.2g, sodium lauryl sulfate 0.8g, aluminium-magnesium silicate 0.5g, sodium benzoate 0.1g and saccharin sodium 0.2g, Mint Essence 1.2g.
Extractum formula: Cortex Eucommiae 5g, Rhizoma Drynariae 5g, Rhizoma Anemarrhenae 5g and Halitum 2g.
Technique:
The preparation of drug extract: take the Cortex Eucommiae, Rhizoma Drynariae, the Rhizoma Anemarrhenae and Halitum by formula, adds 10 times amount soak by water 3 times, each 1.5h, filters, and merges decoction liquor, and when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, obtains drug extract.
The making of toothpaste: take Polyethylene Glycol, glycerol, sodium carboxymethyl cellulose, xanthan gum, sodium benzoate and saccharin sodium by prescription and add 3 times of water gagings, be heated to 40-50 DEG C, insulation is heated and stirred 1-2h also, and obtained colloid solution, is cooled to 30 DEG C, for subsequent use; Said medicine extractum is added in colloid solution, stirs, then silicon dioxide and aluminium-magnesium silicate are once slowly added in colloid solution, stirring and evenly mixing, then add sodium lauryl sulfate, stirring and evenly mixing, homogenizing, emulsifying, make 100g, sterilizing, pack and get final product.
Usage and dosage: each 1-2g, every day 2 times.
Claims (7)
1. a Halitum eucommia bark toothpaste, is characterized in that: calculate by weight, first makes drug extract, then be made with lotion of toothpaste substrate primarily of Cortex Eucommiae 1-20 part, Rhizoma Drynariae 1-20 part, Rhizoma Anemarrhenae 1-20 part and Halitum 1-20 part.
2. Halitum eucommia bark toothpaste as claimed in claim 1, is characterized in that: calculate by weight, first makes drug extract, then be made with lotion of toothpaste substrate primarily of Cortex Eucommiae 5-15 part, Rhizoma Drynariae 5-15 part, Rhizoma Anemarrhenae 5-15 part and Halitum 5-15 part.
3. Halitum eucommia bark toothpaste as claimed in claim 2, is characterized in that: calculate by weight, first makes drug extract, then be made with lotion of toothpaste substrate primarily of the Cortex Eucommiae 10 parts, Rhizoma Drynariae 10 parts, the Rhizoma Anemarrhenae 10 parts and Halitum 10 parts.
4. the Halitum eucommia bark toothpaste according to any one of claim 1-3, it is characterized in that, calculate by weight, be made primarily of said medicine extractum 1.5-3 part, silicon dioxide 7-25 part, Polyethylene Glycol 8-28 part, glycerol 15-45 part, sodium carboxymethyl cellulose 0.5-1 part, xanthan gum 0.2-0.8 part, sodium lauryl sulfate 0.8-1.4 part, aluminium-magnesium silicate 0.5-1 part, sodium benzoate 0.1-0.3 part and saccharin sodium 0.2-0.8 part.
5. Halitum eucommia bark toothpaste as claimed in claim 4, it is characterized in that, calculate by weight, be made primarily of said medicine extractum 2 parts, silica 14 parts, Polyethylene Glycol 16 parts, glycerol 30 parts, sodium carboxymethyl cellulose 0.8 part, xanthan gum 0.4 part, sodium lauryl sulfate 1.2 parts, aluminium-magnesium silicate 0.8 part, sodium benzoate 0.2 part and saccharin sodium 0.4 part.
6. the Halitum eucommia bark toothpaste according to any one of claim 1-3, it is characterized in that: described drug extract is prepared like this: take the Cortex Eucommiae, Rhizoma Drynariae, the Rhizoma Anemarrhenae and Halitum by formula, add 10 times amount soak by water 3 times, each 1.5h, filter, merge decoction liquor, when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, obtains drug extract.
7. the manufacture method of the Halitum eucommia bark toothpaste as described in claim 1-6, it is characterized in that: take Polyethylene Glycol, glycerol, sodium carboxymethyl cellulose, xanthan gum, sodium benzoate and saccharin sodium by prescription, add 3 times of water gagings, be heated to 40-50 DEG C, insulation is heated and stirred 1-2h also, obtained colloid solution, is cooled to 30 DEG C, for subsequent use; Said medicine extractum is added in colloid solution, stirs, then silicon dioxide and aluminium-magnesium silicate are slowly added in colloid solution successively, stirring and evenly mixing, then add sodium lauryl sulfate, stirring and evenly mixing, homogenizing, emulsifying, sterilizing, pack and get final product.
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| CN107174561A (en) * | 2017-07-29 | 2017-09-19 | 何家平 | A kind of Chinese herbal toothpaste technique without rubbing agent |
| CN114886829A (en) * | 2021-08-10 | 2022-08-12 | 李振阳 | Toothpaste for treating oral problems and preparation method thereof |
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