CN105641060A - Medicine composition with body building and yang tonifying functions - Google Patents
Medicine composition with body building and yang tonifying functions Download PDFInfo
- Publication number
- CN105641060A CN105641060A CN201610075520.8A CN201610075520A CN105641060A CN 105641060 A CN105641060 A CN 105641060A CN 201610075520 A CN201610075520 A CN 201610075520A CN 105641060 A CN105641060 A CN 105641060A
- Authority
- CN
- China
- Prior art keywords
- parts
- gecko
- testis
- herba
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003814 drug Substances 0.000 title abstract description 16
- 230000006870 function Effects 0.000 title abstract description 4
- 239000000203 mixture Substances 0.000 title abstract description 4
- 229940079593 drug Drugs 0.000 title description 8
- 210000001550 testis Anatomy 0.000 claims abstract description 64
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 45
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 45
- 235000008434 ginseng Nutrition 0.000 claims abstract description 45
- 210000003899 penis Anatomy 0.000 claims abstract description 33
- 241000005787 Cistanche Species 0.000 claims abstract description 32
- 240000005739 Eurycoma longifolia Species 0.000 claims abstract description 32
- 241000208340 Araliaceae Species 0.000 claims description 44
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 40
- 239000000843 powder Substances 0.000 claims description 40
- 239000008194 pharmaceutical composition Substances 0.000 claims description 37
- 241000756943 Codonopsis Species 0.000 claims description 31
- 241000237903 Hirudo Species 0.000 claims description 31
- 210000001320 hippocampus Anatomy 0.000 claims description 31
- 239000002775 capsule Substances 0.000 claims description 24
- 229920002472 Starch Polymers 0.000 claims description 20
- 238000000605 extraction Methods 0.000 claims description 20
- 239000000706 filtrate Substances 0.000 claims description 20
- 238000010438 heat treatment Methods 0.000 claims description 20
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 20
- 239000008107 starch Substances 0.000 claims description 20
- 235000019698 starch Nutrition 0.000 claims description 20
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 10
- 210000003056 antler Anatomy 0.000 claims description 10
- 239000006071 cream Substances 0.000 claims description 10
- 239000008187 granular material Substances 0.000 claims description 10
- 235000019359 magnesium stearate Nutrition 0.000 claims description 10
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims description 10
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 10
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 10
- 238000002360 preparation method Methods 0.000 claims description 10
- 238000010298 pulverizing process Methods 0.000 claims description 10
- 238000010992 reflux Methods 0.000 claims description 10
- 239000002002 slurry Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 239000002552 dosage form Substances 0.000 claims description 8
- 239000002671 adjuvant Substances 0.000 claims description 4
- 210000003734 kidney Anatomy 0.000 abstract description 15
- 230000036039 immunity Effects 0.000 abstract description 4
- 239000000463 material Substances 0.000 abstract description 2
- 241000893536 Epimedium Species 0.000 abstract 1
- 241000270290 Gekkota Species 0.000 abstract 1
- 235000018142 Hedysarum alpinum var americanum Nutrition 0.000 abstract 1
- 240000006461 Hedysarum alpinum var. americanum Species 0.000 abstract 1
- 241000545744 Hirudinea Species 0.000 abstract 1
- 241000237502 Ostreidae Species 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 241001247203 Syngnathidae Species 0.000 abstract 1
- 240000008042 Zea mays Species 0.000 abstract 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract 1
- 235000005822 corn Nutrition 0.000 abstract 1
- 235000018905 epimedium Nutrition 0.000 abstract 1
- 235000020636 oyster Nutrition 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 13
- 230000000694 effects Effects 0.000 description 13
- 210000004369 blood Anatomy 0.000 description 11
- 201000001881 impotence Diseases 0.000 description 9
- 230000008093 supporting effect Effects 0.000 description 8
- 230000008901 benefit Effects 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 210000000952 spleen Anatomy 0.000 description 5
- 208000010228 Erectile Dysfunction Diseases 0.000 description 4
- 206010003549 asthenia Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 239000000796 flavoring agent Substances 0.000 description 4
- 235000019634 flavors Nutrition 0.000 description 4
- 210000000629 knee joint Anatomy 0.000 description 4
- 206010036596 premature ejaculation Diseases 0.000 description 4
- 230000001568 sexual effect Effects 0.000 description 4
- 206010010774 Constipation Diseases 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 210000003414 extremity Anatomy 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 210000001624 hip Anatomy 0.000 description 2
- 208000021267 infertility disease Diseases 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 210000003127 knee Anatomy 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 210000002435 tendon Anatomy 0.000 description 2
- 230000001256 tonic effect Effects 0.000 description 2
- 102000005606 Activins Human genes 0.000 description 1
- 108010059616 Activins Proteins 0.000 description 1
- 201000000736 Amenorrhea Diseases 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- 206010028372 Muscular weakness Diseases 0.000 description 1
- 208000007443 Neurasthenia Diseases 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 206010052004 Organic erectile dysfunction Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000028017 Psychotic disease Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 102000019197 Superoxide Dismutase Human genes 0.000 description 1
- 108010012715 Superoxide dismutase Proteins 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000488 activin Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 230000000954 anitussive effect Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 229940124584 antitussives Drugs 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 231100000895 deafness Toxicity 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 208000016354 hearing loss disease Diseases 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 230000002607 hemopoietic effect Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 201000003453 lung abscess Diseases 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000004899 motility Effects 0.000 description 1
- 230000036473 myasthenia Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 208000012201 sexual and gender identity disease Diseases 0.000 description 1
- 208000015891 sexual disease Diseases 0.000 description 1
- 230000036299 sexual function Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000021595 spermatogenesis Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 230000002537 thrombolytic effect Effects 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/484—Plasmin (3.4.21.7)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a medicine composition with body building and yang tonifying functions. The medicine is mainly prepared from, by weight, 5-20 parts of leeches, 80-110 parts of the herb of korean epimedium, 15-28 parts of herba cistanche, 20-30 parts of penis cervi, 8-12 parts of corn cervi pantotrichum, 18-28 parts of geckos, 2-6 parts of gecko male testicles, 15-30 parts of ginseng, 15-28 parts of sea horses, 12-25 parts of herba cynomorii, 15-28 parts of eurycoma longifolia, 15-30 parts of oysters, 45-58 parts of the root of hairy asiabell and 22-36 parts of liquorice roots. The medicine materials are reasonable in compatibility, and the aims of building the body, invigorating the kidney and tonifying yang and boosting the immunity of the human body are achieved.
Description
Technical field
The present invention relates to pharmaceutical technology field, particularly the pharmaceutical composition of a kind of body-building and tonifying yang.
Background technology
Quickening along with modern life rhythm, irregular, life that overfatigue, pressure are excessive for a long time, it is easily caused the human body functional disorder of people, shows as the symptoms such as insufficiency of kidney-YANG, blood and essence asthenia, soreness of waist and knee joint, extremity cold, fatigue and asthenia, impotence and premature ejaculation, early whitening of beard and hair. People are for building body, kidney invigorating and YANG supporting, medicine or the health product that can select some kidney invigorating and YANG supporting are taken, but, the medea that the traditional Chinese medical science or doctor trained in Western medicine develop now is various in style, but due to medea market, dragons and fishes jumbled together, the composition of medea is indefinite so that a lot of user all has doubt for medea and kidney-reinforcing drug.
Summary of the invention
The invention provides the pharmaceutical composition of a kind of body-building and tonifying yang, it is possible to building body, kidney invigorating and YANG supporting, raising body immunity.
For achieving the above object, the technical scheme is that
A kind of pharmaceutical composition of body-building and tonifying yang, it is mainly made up by weight ratio of following components:
Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 15 ~ 28 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 45 ~ 58 parts, 22 ~ 36 parts of Radix Glycyrrhizae.
The pharmaceutical composition of above-described body-building and tonifying yang, it is preferable that be mainly made up by weight ratio of following components:
Hirudo 12 parts, Herba Epimedii 105, Herba Cistanches 22 parts, Penis et testis cervi 25 parts, 10 parts of Cornu Cervi Pantotrichum, Gecko 23 parts, Gecko hero testis 4 parts, Radix Ginseng 23 parts, Hippocampus 23 parts, Herba Cynomorii 19 parts, Eurycoma longifolia 23 parts, Concha Ostreae 24 parts, Radix Codonopsis 52 parts, 31 parts of Radix Glycyrrhizae.
The above pharmaceutical composition can add customary adjuvant by practice of pharmacy and make any dosage form of clinical acceptance; It is capsule as preferred described dosage form.
The preparation method of the pharmaceutical composition of above-described body-building and tonifying yang, comprises the following steps:
(1) following component is weighed by weight: Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 15 ~ 28 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 45 ~ 58 parts, 22 ~ 36 parts of Radix Glycyrrhizae;
(2) Cornu Cervi Pantotrichum and Radix Ginseng grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Present invention also offers another technical scheme, the pharmaceutical composition of a kind of body-building and tonifying yang, it is mainly made up by weight ratio of following components:
Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 15 ~ 28 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 45 ~ 58 parts, 22 ~ 36 parts of Radix Glycyrrhizae, Lumbrukinase 10 ~ 15 parts.
The pharmaceutical composition of above-described body-building and tonifying yang, it is preferable that be mainly made up by weight ratio of following components: Hirudo 12 parts, Herba Epimedii 105, Herba Cistanches 22 parts, Penis et testis cervi 25 parts, 10 parts of Cornu Cervi Pantotrichum, Gecko 23 parts, Gecko hero testis 4 parts, Radix Ginseng 23 parts, Hippocampus 23 parts, Herba Cynomorii 19 parts, Eurycoma longifolia 23 parts, Concha Ostreae 24 parts, Radix Codonopsis 52 parts, 31 parts of Radix Glycyrrhizae, Lumbrukinase 13 parts.
The above pharmaceutical composition can add customary adjuvant by practice of pharmacy and make any dosage form of clinical acceptance; As preferably, described dosage form is capsule.
The pharmaceutical composition of above-described body-building and tonifying yang, comprises the following steps:
(1) following component is weighed by weight: Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 15 ~ 28 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 45 ~ 58 parts, 22 ~ 36 parts of Radix Glycyrrhizae, Lumbrukinase 10 ~ 15 parts;
(2) Cornu Cervi Pantotrichum and Radix Ginseng grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder, Lumbrukinase and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
The pharmaceutical composition of the present invention is mainly made up of Hirudo, Herba Epimedii, Herba Cistanches, Penis et testis cervi, Cornu Cervi Pantotrichum, Gecko, Gecko hero testis, Radix Ginseng, Hippocampus, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Radix Glycyrrhizae and Lumbrukinase, and in side, effect of each medicine is:
Hirudo: the salty hardship of nature and flavor, flat;Have invigorate blood circulation, effect of dissipating blood stasis, the clear stasis of blood, can be used for treating amenorrhea, traumatic injury etc.;
Herba Epimedii: nature and flavor are pungent, sweet, temperature, there is kidney invigorating and YANG supporting, bone and muscle strengthening, invigorate vital energy and reinforce the heart, effect of expelling wind and removing dampness, it is adaptable to the soft disease such as unable for the treatment of sexual impotence, seminal emission, premature ejaculation, sexual disorder, menoxenia, climacteric syndrome, hypertension, rheumatalgia, hemiplegia, numb limbs and tense tendons, knee joint;
Herba Cistanches: meridian distribution of property and flavor is sweet, salty, temperature; Function cures mainly kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation; For sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, dryness of the intestine constipation;
Penis et testis cervi: warm in nature, salty in the mouth is pungent, nontoxic; The kidney invigorating essence, invigorating kidney-YANG, benefit essence, strong waist knee joint; Curing mainly strain of suffering from a deficiency of the kidney, soreness of waist and knee joint, deafness and tinnitus, sexual impotence, seminal emission, premature ejaculation, cold womb is infertile, and leukorrhagia is rare clearly;
Cornu Cervi Pantotrichum: warm in nature and not dry, has and rouses oneself and improve body function, to patient after asthenia universalis, prolonged illness, have good Tonic Action; Li Shizhen (1518-1593 A.D.) claims Cornu Cervi Pantotrichum " being good at kidney invigorating and YANG supporting, spermatogenesis benefit blood, the strong bone of benefit marrow " in Compendium of Material Medica;
Gecko: " detailed outline " is recorded, tonifying the lung gas, benefiting essence-blood, Dingchuan antitussive, treats lung abscess and quenches one's thirst, supporing yang road; " book on Chinese herbal medicine is new again " is recorded, warming middle-JIAO kidney tonifying, and controlling nocturnal emission with astringent drugs is supporing yang, treating stranguria, promoting the circulation of blood;
Gecko hero testis: i.e. Gecko testis, has kidney invigorating and YANG supporting, tonifying the lung Dingchuan, blood nourishing body building, anti-ageing effect prolonged life;
Radix Ginseng: Radix Ginseng is described as " king of BAICAO " from ancient times, is the superfine product of " YIN nourishing is mended raw, strengthening the body resistance ", containing multiple Saponin and polysaccharide composition, leachate slowly can be absorbed by skin and without pessimal stimulation, energy skin expansion blood capillary, promote cutaneous circulation, increase skin-nourishing; The fleshy tap root of Radix Ginseng is famous strong tonic, it is adaptable to adjusts blood pressure, recover the diseases such as cardiac function, neurasthenia and physical weakness, also eliminate the phlegm, stomach invigorating, diuresis, the effect such as excitement;
Hippocampus: there is the medicinal efficacies such as building body, kidney invigorating and YANG supporting, relaxing muscles and tendons and activating QI and blood in the collateral, anti-inflammatory analgetic, tranquillizing and allaying excitement, relieving cough and asthma;
Herba Cynomorii: can the kidney invigorating, benefit essence, moisturize, cure mainly impotence and seminal emission, soreness of the waist and knees, dryness of the intestine constipation, to paralysis with improve that sexual function is weak to have certain effect;
Eurycoma longifolia: bitter in the mouth, cool in nature, it is referred to as " natural philter ", there is effect of heat clearing away, preventing the attack (or recurrence) of malaria, dampness removing jaundice eliminating, tonifying YANG;
Concha Ostreae: nature and flavor are salty, is slightly cold; There are convergence, calmness, removing toxic substances, analgesic effect; Rich in new element, the vigor of mankind spermatozoon can be improved;
Radix Codonopsis: sweet in the mouth, has effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, anticancer, blood pressure lowering, anti-hypoxia, defying age, it is also possible to strengthen body immunity, improves the activity of superoxide dismutase, strengthens the ability eliminating free radical; With ginseng compatibility can invigorating the spleen to benefit the lung, promote the production of body fluid and nourish blood;
Radix Glycyrrhizae: there is many-sided effects such as invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, eliminating fire and detoxication, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription;
Lumbrukinase: there is thrombolytic, anticoagulant and go fine effect; Lumbrukinase is the proteolytic enzyme that activity is the highest, can the various cell of human activin.
The present invention is the kidney invigorating gas with Herba Epimedii, Herba Cistanches, Penis et testis cervi, Cornu Cervi Pantotrichum, Gecko, Gecko hero testis, Hippocampus, Herba Cynomorii, Eurycoma longifolia and Partition in Fructus Juglandis, supports the principal agent of essence and blood, tonifying YANG, assistant is with the Hirudo Activating stasis of blood, help and improve motility of sperm with Concha Ostreae, help with Radix Ginseng, Radix Codonopsis, Radix Glycyrrhizae invigorating the spleen and replenishing QI, hold up this solid just, separately also have and be equipped with Lumbrukinase active cell activity, the present invention reasonable compatibility by said medicine, reaches the purpose of building body, kidney invigorating and YANG supporting, raising body immunity.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described, but protection scope of the present invention is not limited to following example:
One, the preparation of the pharmaceutical composition of body-building and tonifying yang
Embodiment 1
The pharmaceutical composition of body-building and tonifying yang, is mainly made up by weight ratio of following components: Hirudo 12 parts, Herba Epimedii 105, Herba Cistanches 22 parts, Penis et testis cervi 25 parts, 10 parts of Cornu Cervi Pantotrichum, Gecko 23 parts, Gecko hero testis 4 parts, Radix Ginseng 23 parts, Hippocampus 23 parts, Herba Cynomorii 19 parts, Eurycoma longifolia 23 parts, Concha Ostreae 24 parts, Radix Codonopsis 52 parts, 31 parts of Radix Glycyrrhizae.
The preparation method of aforementioned pharmaceutical compositions is:
(1) said components is weighed by weight;
(2) Cornu Cervi Pantotrichum and Radix Ginseng grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Embodiment 2
The pharmaceutical composition of body-building and tonifying yang, is mainly made up by weight ratio of following components: Hirudo 5 parts, Herba Epimedii 80, Herba Cistanches 15 parts, Penis et testis cervi 20 parts, 8 parts of Cornu Cervi Pantotrichum, Gecko 18 parts, Gecko hero testis 2 parts, Radix Ginseng 15 parts, Hippocampus 15 parts, Herba Cynomorii 12 parts, Eurycoma longifolia 15 parts, Concha Ostreae 15 parts, Radix Codonopsis 45 parts, 22 parts of Radix Glycyrrhizae.
The preparation method of aforementioned pharmaceutical compositions is:
(1) said components is weighed by weight;
(2) Cornu Cervi Pantotrichum and Radix Ginseng grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Embodiment 3
The pharmaceutical composition of body-building and tonifying yang, is mainly made up by weight ratio of following components: Hirudo 20 parts, Herba Epimedii 110, Herba Cistanches 28 parts, Penis et testis cervi 30 parts, 12 parts of Cornu Cervi Pantotrichum, Gecko 28 parts, Gecko hero testis 6 parts, Radix Ginseng 30 parts, Hippocampus 28 parts, Herba Cynomorii 25 parts, Eurycoma longifolia 28 parts, Concha Ostreae 30 parts, Radix Codonopsis 58 parts, 36 parts of Radix Glycyrrhizae.
The preparation method of aforementioned pharmaceutical compositions is:
(1) said components is weighed by weight;
(2) Cornu Cervi Pantotrichum and Radix Ginseng grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Embodiment 4
The pharmaceutical composition of a kind of body-building and tonifying yang, is mainly made up by weight ratio of following components: Hirudo 12 parts, Herba Epimedii 105, Herba Cistanches 22 parts, Penis et testis cervi 25 parts, 10 parts of Cornu Cervi Pantotrichum, Gecko 23 parts, Gecko hero testis 4 parts, Radix Ginseng 23 parts, Hippocampus 23 parts, Herba Cynomorii 19 parts, Eurycoma longifolia 23 parts, Concha Ostreae 24 parts, Radix Codonopsis 52 parts, 31 parts of Radix Glycyrrhizae, Lumbrukinase 13 parts.
The preparation method of aforementioned pharmaceutical compositions is:
(1) said components is weighed by weight;
(2) Cornu Cervi Pantotrichum and Radix Ginseng grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder, Lumbrukinase and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Embodiment 5
The pharmaceutical composition of a kind of body-building and tonifying yang, is mainly made up by weight ratio of following components: Hirudo 5 parts, Herba Epimedii 80, Herba Cistanches 15 parts, Penis et testis cervi 20 parts, 8 parts of Cornu Cervi Pantotrichum, Gecko 18 parts, Gecko hero testis 2 parts, Radix Ginseng 15 parts, Hippocampus 15 parts, Herba Cynomorii 12 parts, Eurycoma longifolia 15 parts, Concha Ostreae 15 parts, Radix Codonopsis 45 parts, 22 parts of Radix Glycyrrhizae, Lumbrukinase 10 parts.
The preparation method of aforementioned pharmaceutical compositions is:
(1) said components is weighed by weight;
(2) Cornu Cervi Pantotrichum and Radix Ginseng grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder, Lumbrukinase and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Embodiment 6
The pharmaceutical composition of a kind of body-building and tonifying yang, is mainly made up by weight ratio of following components: Hirudo 20 parts, Herba Epimedii 110, Herba Cistanches 28 parts, Penis et testis cervi 30 parts, 12 parts of Cornu Cervi Pantotrichum, Gecko 28 parts, Gecko hero testis 6 parts, Radix Ginseng 30 parts, Hippocampus 28 parts, Herba Cynomorii 25 parts, Eurycoma longifolia 28 parts, Concha Ostreae 30 parts, Radix Codonopsis 58 parts, 36 parts of Radix Glycyrrhizae, Lumbrukinase 15 parts.
The preparation method of aforementioned pharmaceutical compositions is:
(1) said components is weighed by weight;
(2) Cornu Cervi Pantotrichum and Radix Ginseng grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A;Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder, Lumbrukinase and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Two, clinical practice
1, the selection of case:
Select impotence patient, through 150 example clinical observations.
(1) inclusive criteria:
A. there are spouse male, 48 years old mean age at the age between 30-60 year.
B. tcm diagnosis impotence patient is standard: during between twenty and fifty man's sexual intercourse, owing to penis can not erect effectively, and causes more than the 75% of sexual intercourse plan and can not carry out, namely diagnosable for sexual impotence.
C. without organic disease.
C. can partner treatment, the patient of further consultation on time.
(2) exclusion standard
A. the age is below 30 years old or more than 60 years old person.
B. the organic impotence patient made a definite diagnosis.
C. severe primary disease and spirit, the psychotics such as cardiovascular, liver, kidney and hemopoietic system it are associated with.
D. allergic constitution or to multi-medicament allergy sufferers.
E. not by regulation medication or therapy discontinued, it is impossible to judge curative effect or data is not congruent affects the treatment or safety judgement person.
2, clinical trial:
(1) therapeutic scheme:
A. treatment group: by the above-mentioned embodiment 1 prepared and embodiment 4 sample, for clinical trial. Oral, one time 2,3 times on the one. The course for the treatment of: medication 45 days.
B. matched group: NANBAO JIAONANG (commercially available). Oral, one time 3,2 times on the one. The course for the treatment of: medication 45 days.
(2) efficacy determination:
A. effective: erection > 90 after treatment, more than the 50% of sexual intercourse chance can success.
B. effective: after treatment, erection makes moderate progress, more than the 25% of sexual intercourse chance can success.
C. invalid: before and after medication, indices is all without improving.
(3) result of the test:
For treating 150 example outpatients. By above-mentioned embodiment 1, embodiment 4 and the NANBAO JIAONANG prepared, it is respectively used to patient: treatment group: 100 examples (take 50 examples of embodiment 1, take 50 examples of embodiment 4), matched group: 50 examples. During clinical trial, withdraw other medicines and health nutrient. The results detailed in following table:
Group | Effective | Effectively | Invalid | Effective percentage |
Embodiment 1 | 20 | 20 | 10 | 80% |
Embodiment 4 | 25 | 20 | 5 | 90% |
Matched group | 20 | 19 | 11 | 78% |
Result shows: the effective percentage of embodiment 4 reaches 90%, is better than matched group; The effective percentage of embodiment 1 reaches 80%, suitable with matched group. Patient is after treatment, it is common to reaction can improve the symptom of myasthenia of limbs, impotence and premature ejaculation.
Claims (10)
1. the pharmaceutical composition of a body-building and tonifying yang, it is characterised in that it is mainly made up by weight ratio of following components:
Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 15 ~ 28 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 45 ~ 58 parts, 22 ~ 36 parts of Radix Glycyrrhizae.
2. the pharmaceutical composition of body-building and tonifying yang according to claim 1, it is characterised in that it is mainly made up by weight ratio of following components:
Hirudo 12 parts, Herba Epimedii 105, Herba Cistanches 22 parts, Penis et testis cervi 25 parts, 10 parts of Cornu Cervi Pantotrichum, Gecko 23 parts, Gecko hero testis 4 parts, Radix Ginseng 23 parts, Hippocampus 23 parts, Herba Cynomorii 19 parts, Eurycoma longifolia 23 parts, Concha Ostreae 24 parts, Radix Codonopsis 52 parts, 31 parts of Radix Glycyrrhizae.
3. the pharmaceutical composition of body-building and tonifying yang according to claim 1 and 2, it is characterised in that:
Described pharmaceutical composition adds customary adjuvant by practice of pharmacy and makes any dosage form of clinical acceptance.
4. the pharmaceutical composition of body-building and tonifying yang according to claim 3, it is characterised in that:
Described dosage form is capsule.
5. the preparation method of the pharmaceutical composition of body-building and tonifying yang according to claim 1, it is characterised in that comprise the following steps:
(1) following component is weighed by weight: Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 15 ~ 28 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 45 ~ 58 parts, 22 ~ 36 parts of Radix Glycyrrhizae;
(2) Cornu Cervi Pantotrichum and Radix Ginseng grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
6. the pharmaceutical composition of a body-building and tonifying yang, it is characterised in that it is mainly made up by weight ratio of following components:
Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 15 ~ 28 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 45 ~ 58 parts, 22 ~ 36 parts of Radix Glycyrrhizae, Lumbrukinase 10 ~ 15 parts.
7. the pharmaceutical composition of body-building and tonifying yang according to claim 6, it is characterised in that it is mainly made up by weight ratio of following components:
Hirudo 12 parts, Herba Epimedii 105, Herba Cistanches 22 parts, Penis et testis cervi 25 parts, 10 parts of Cornu Cervi Pantotrichum, Gecko 23 parts, Gecko hero testis 4 parts, Radix Ginseng 23 parts, Hippocampus 23 parts, Herba Cynomorii 19 parts, Eurycoma longifolia 23 parts, Concha Ostreae 24 parts, Radix Codonopsis 52 parts, 31 parts of Radix Glycyrrhizae, Lumbrukinase 13 parts.
8. the pharmaceutical composition of the body-building and tonifying yang according to claim 6 or 7, it is characterised in that:
Described pharmaceutical composition adds customary adjuvant by practice of pharmacy and makes any dosage form of clinical acceptance.
9. the pharmaceutical composition of body-building and tonifying yang according to claim 8, it is characterised in that:
Described dosage form is capsule.
10. the preparation method of the pharmaceutical composition of body-building and tonifying yang according to claim 6, it is characterised in that comprise the following steps:
(1) following component is weighed by weight: Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 15 ~ 28 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 45 ~ 58 parts, 22 ~ 36 parts of Radix Glycyrrhizae, Lumbrukinase 10 ~ 15 parts;
(2) Cornu Cervi Pantotrichum and Radix Ginseng grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder, Lumbrukinase and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610075520.8A CN105641060A (en) | 2016-02-03 | 2016-02-03 | Medicine composition with body building and yang tonifying functions |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610075520.8A CN105641060A (en) | 2016-02-03 | 2016-02-03 | Medicine composition with body building and yang tonifying functions |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105641060A true CN105641060A (en) | 2016-06-08 |
Family
ID=56489247
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610075520.8A Withdrawn CN105641060A (en) | 2016-02-03 | 2016-02-03 | Medicine composition with body building and yang tonifying functions |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105641060A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110638855A (en) * | 2019-08-22 | 2020-01-03 | 长沙市惠瑞生物科技有限公司 | Composition for improving kidney function |
CN114796436A (en) * | 2022-05-19 | 2022-07-29 | 北京荣寿堂生物科技有限公司 | Kidney-tonifying and yang-strengthening capsule and preparation method thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1095606A (en) * | 1993-05-21 | 1994-11-30 | 吴海元 | " Xianshou " nutritious liquor |
CN104888206A (en) * | 2015-06-19 | 2015-09-09 | 广西复鑫益生物科技有限公司平南分公司 | Combination drug containing hirudin for treating cardiovascular and cerebrovascular diseases |
CN105233010A (en) * | 2015-11-13 | 2016-01-13 | 关玉斌 | Wine capable of invigorating kidney and strengthening Yang and making method thereof |
-
2016
- 2016-02-03 CN CN201610075520.8A patent/CN105641060A/en not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1095606A (en) * | 1993-05-21 | 1994-11-30 | 吴海元 | " Xianshou " nutritious liquor |
CN104888206A (en) * | 2015-06-19 | 2015-09-09 | 广西复鑫益生物科技有限公司平南分公司 | Combination drug containing hirudin for treating cardiovascular and cerebrovascular diseases |
CN105233010A (en) * | 2015-11-13 | 2016-01-13 | 关玉斌 | Wine capable of invigorating kidney and strengthening Yang and making method thereof |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110638855A (en) * | 2019-08-22 | 2020-01-03 | 长沙市惠瑞生物科技有限公司 | Composition for improving kidney function |
CN114796436A (en) * | 2022-05-19 | 2022-07-29 | 北京荣寿堂生物科技有限公司 | Kidney-tonifying and yang-strengthening capsule and preparation method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103520654B (en) | A kind of Chinese medicine composition being used for the treatment of knee osteoarthritis and preparation method thereof | |
CN101015651A (en) | Medicine for treating protrusion of lumbar intervertebral disc | |
CN105641466A (en) | Traditional Chinese medicine composition for invigorating kidney and strengthening yang and preparing method thereof | |
CN104825914A (en) | Traditional Chinese medicinal preparation for assisted treatment of breast cancer | |
CN101129878A (en) | Traditional Chinese medicine preparation for treating uterine prolapse | |
CN105641060A (en) | Medicine composition with body building and yang tonifying functions | |
CN102716334A (en) | Chinese medicinal composition for dispelling the cold and removing stasis | |
CN105641330A (en) | Traditional Chinese medicine composition for invigorating kidney and strengthening yang | |
CN102125664B (en) | Chinese medicinal preparation for treating cervical spondylosis | |
CN107536901A (en) | A kind of bubble pin health-care Chinese medicinal composition of dispersing blood stasis promoting blood circulation and stopping pain and preparation method thereof | |
CN103585596B (en) | Traditional Chinese medicine composition for treating migraine | |
CN105664143A (en) | Medicinal composition with body building and yang strengthening functions and preparation method thereof | |
CN105663383A (en) | Traditional Chinese medicine composition with body building and yang strengthening functions | |
CN105617388A (en) | Kidney-tonifying yang-strengthening medicine composition | |
CN101690797A (en) | Traditional Chinese medicine for treating rheumatism and rheumatoid diseases | |
CN104800610A (en) | Traditional Chinese medicine preparation for treating Parkinson's disease and preparation method thereof | |
CN104888133A (en) | Traditional Chinese medicine composition for treatment of coronary heart disease | |
CN104840902A (en) | Traditional Chinese medicine preparation for treating ovarian tumor | |
CN104257986A (en) | Traditional Chinese medicine for treating nephritis | |
CN103463463A (en) | Traditional Chinese medicine preparation for replenishing and activating blood and dispelling wind and removing dampness | |
CN103961555A (en) | Traditional Chinese medicine preparation for treating peripheral nerve injury and preparation method thereof | |
CN103463397A (en) | Traditional Chinese medicine composition for treating deficiency of kidney-yin | |
CN107303373A (en) | Treat the healthy medicated wine of a variety of diseases | |
CN104840814A (en) | Traditional Chinese medicine combination for treating senile femoral head necrosis | |
CN106619852A (en) | Traditional Chinese medicine lavipeditum life cultivation and health preservation prescription with effects of warming channels and dispersing cold, and dredging grain of skin and texture of the subcutaneous flesh |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20170425 Address after: 530023 the Guangxi Zhuang Autonomous Region City, ancient city road, No. 33 Seismological Bureau building, building 6, unit 15, building 2, floor 6415, Applicant after: Li Xiaoting Address before: 530007 the Guangxi Zhuang Autonomous Region high tech Avenue, No. 62 Guanghui building, No. 1419, Nanning Applicant before: Nanning Pindi Biological Engineering Co., Ltd. |
|
WW01 | Invention patent application withdrawn after publication | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20160608 |