CN105641466A - Traditional Chinese medicine composition for invigorating kidney and strengthening yang and preparing method thereof - Google Patents
Traditional Chinese medicine composition for invigorating kidney and strengthening yang and preparing method thereof Download PDFInfo
- Publication number
- CN105641466A CN105641466A CN201610075517.6A CN201610075517A CN105641466A CN 105641466 A CN105641466 A CN 105641466A CN 201610075517 A CN201610075517 A CN 201610075517A CN 105641466 A CN105641466 A CN 105641466A
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- radix
- gecko
- testis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
- A61K36/068—Cordyceps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/52—Juglandaceae (Walnut family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Marine Sciences & Fisheries (AREA)
- Virology (AREA)
- Reproductive Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition for invigorating kidney and strengthening yang. The traditional Chinese medicine composition is mainly prepared from, by weight, 5-20 parts of leeches, 80-110 parts of herba epimedii, 15-28 parts of herba cistanches, 20-30 parts of penis cervi, 8-12 parts of corn cervi pantotrichum, 18-28 parts of geckoes, 2-6 parts of gecko testicles, 15-30 parts of ginseng, 15-28 parts of hippocampi, 12-25 parts of herba cynomorii, 5-12 parts of eurycoma longifolia, 15-30 parts of oysters, 30-40 parts of radix codonopsis, 1-3 parts of diaphragma juglandis, 2-6 parts of prepared fleece flower roots, 6-10 parts of cordyceps sinensis, 10-15 parts of dendrobes and 22-36 parts of liquorice roots. A preparing method includes the step that an auxiliary material is added to prepare capsules. By means of reasonable compatibility of medicine, the traditional Chinese medicine composition achieves the purposes of building the body, invigorating kidney, strengthening yang and improving immunity.
Description
Technical field
The present invention relates to pharmaceutical technology field, particularly a kind of Traditional Chinese medicine composition for invigorating kidney and strengthening yang and preparation method thereof.
Background technology
Quickening along with modern life rhythm, irregular, life that overfatigue, pressure are excessive for a long time, it is easily caused the human body functional disorder of people, shows as the symptoms such as insufficiency of kidney-YANG, blood and essence asthenia, soreness of waist and knee joint, extremity cold, fatigue and asthenia, impotence and premature ejaculation, early whitening of beard and hair. People are for building body, kidney invigorating and YANG supporting, medicine or the health product that can select some kidney invigorating and YANG supporting are taken, but, the medea that the traditional Chinese medical science or doctor trained in Western medicine develop now is various in style, but due to medea market, dragons and fishes jumbled together, the composition of medea is indefinite so that a lot of user all has doubt for medea and kidney-reinforcing drug.
Summary of the invention
The invention provides a kind of Traditional Chinese medicine composition for invigorating kidney and strengthening yang and preparation method thereof, prepared Chinese medicine preparation can building body, kidney invigorating and YANG supporting, raising body immunity.
For achieving the above object, the technical scheme is that
A kind of Traditional Chinese medicine composition for invigorating kidney and strengthening yang, it is mainly made up by weight ratio of following components:
Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 5 ~ 12 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 30 ~ 40 parts, Partition in Fructus Juglandis 1 ~ 3 part, Radix Polygoni Multiflori Preparata 2 ~ 6 parts, Cordyceps 6 ~ 10 parts, Herba Dendrobii 10 ~ 15 parts, 22 ~ 36 parts of Radix Glycyrrhizae.
Above-described Traditional Chinese medicine composition for invigorating kidney and strengthening yang, it is preferable that be mainly made up by weight ratio of following components:
Hirudo 12 parts, Herba Epimedii 105, Herba Cistanches 22 parts, Penis et testis cervi 25 parts, 10 parts of Cornu Cervi Pantotrichum, Gecko 23 parts, Gecko hero testis 4 parts, Radix Ginseng 23 parts, Hippocampus 23 parts, Herba Cynomorii 19 parts, Eurycoma longifolia 8 parts, Concha Ostreae 24 parts, Radix Codonopsis 35 parts, Partition in Fructus Juglandis 2 parts, Radix Polygoni Multiflori Preparata 4 parts, Cordyceps 8 parts, Herba Dendrobii 13 parts, 31 parts of Radix Glycyrrhizae.
The above pharmaceutical composition can add customary adjuvant by practice of pharmacy and make any dosage form of clinical acceptance; It is capsule as preferred described dosage form.
The preparation method of above-described Traditional Chinese medicine composition for invigorating kidney and strengthening yang, comprises the following steps:
(1) following component is weighed by weight: Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110 parts, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 5 ~ 12 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 30 ~ 40 parts, Partition in Fructus Juglandis 1 ~ 3 part, Radix Polygoni Multiflori Preparata 2 ~ 6 parts, Cordyceps 6 ~ 10 parts, Herba Dendrobii 10 ~ 15 parts, 22 ~ 36 parts of Radix Glycyrrhizae;
(2) Cornu Cervi Pantotrichum, Radix Ginseng and Cordyceps grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus and Radix Polygoni Multiflori Preparata, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Partition in Fructus Juglandis, Herba Dendrobii and Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder, Cordyceps powder and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
The pharmaceutical composition of the present invention is mainly made up of Hirudo, Herba Epimedii, Herba Cistanches, Penis et testis cervi, Cornu Cervi Pantotrichum, Gecko, Gecko hero testis, Radix Ginseng, Hippocampus, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Partition in Fructus Juglandis, Radix Polygoni Multiflori Preparata, Cordyceps, Herba Dendrobii and Radix Glycyrrhizae, and in side, effect of each medicine is:
Hirudo: the salty hardship of nature and flavor, flat; Have invigorate blood circulation, effect of dissipating blood stasis, the clear stasis of blood, can be used for treating amenorrhea, traumatic injury etc.;
Herba Epimedii: nature and flavor are pungent, sweet, temperature, there is kidney invigorating and YANG supporting, bone and muscle strengthening, invigorate vital energy and reinforce the heart, effect of expelling wind and removing dampness, it is adaptable to the soft disease such as unable for the treatment of sexual impotence, seminal emission, premature ejaculation, sexual disorder, menoxenia, climacteric syndrome, hypertension, rheumatalgia, hemiplegia, numb limbs and tense tendons, knee joint;
Herba Cistanches: meridian distribution of property and flavor is sweet, salty, temperature; Function cures mainly kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation; For sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, dryness of the intestine constipation;
Penis et testis cervi: warm in nature, salty in the mouth is pungent, nontoxic; The kidney invigorating essence, invigorating kidney-YANG, benefit essence, strong waist knee joint; Curing mainly strain of suffering from a deficiency of the kidney, soreness of waist and knee joint, deafness and tinnitus, sexual impotence, seminal emission, premature ejaculation, cold womb is infertile, and leukorrhagia is rare clearly;
Cornu Cervi Pantotrichum: warm in nature and not dry, has and rouses oneself and improve body function, to patient after asthenia universalis, prolonged illness, have good Tonic Action; Li Shizhen (1518-1593 A.D.) claims Cornu Cervi Pantotrichum " being good at kidney invigorating and YANG supporting, spermatogenesis benefit blood, the strong bone of benefit marrow " in Compendium of Material Medica;
Gecko: " detailed outline " is recorded, tonifying the lung gas, benefiting essence-blood, Dingchuan antitussive, treats lung abscess and quenches one's thirst, supporing yang road; " book on Chinese herbal medicine is new again " is recorded, warming middle-JIAO kidney tonifying, and controlling nocturnal emission with astringent drugs is supporing yang, treating stranguria, promoting the circulation of blood;
Gecko hero testis: i.e. Gecko testis, has kidney invigorating and YANG supporting, tonifying the lung Dingchuan, blood nourishing body building, anti-ageing effect prolonged life;
Radix Ginseng: Radix Ginseng is described as " king of BAICAO " from ancient times, is the superfine product of " YIN nourishing is mended raw, strengthening the body resistance ", containing multiple Saponin and polysaccharide composition, leachate slowly can be absorbed by skin and without pessimal stimulation, energy skin expansion blood capillary, promote cutaneous circulation, increase skin-nourishing; The fleshy tap root of Radix Ginseng is famous strong tonic, it is adaptable to adjusts blood pressure, recover the diseases such as cardiac function, neurasthenia and physical weakness, also eliminate the phlegm, stomach invigorating, diuresis, the effect such as excitement;
Hippocampus: there is the medicinal efficacies such as building body, kidney invigorating and YANG supporting, relaxing muscles and tendons and activating QI and blood in the collateral, anti-inflammatory analgetic, tranquillizing and allaying excitement, relieving cough and asthma;
Herba Cynomorii: can the kidney invigorating, benefit essence, moisturize, cure mainly impotence and seminal emission, soreness of the waist and knees, dryness of the intestine constipation, to paralysis with improve that sexual function is weak to have certain effect;
Eurycoma longifolia: bitter in the mouth, cool in nature, it is referred to as " natural philter ", there is effect of heat clearing away, preventing the attack (or recurrence) of malaria, dampness removing jaundice eliminating, tonifying YANG;
Concha Ostreae: nature and flavor are salty, is slightly cold; There are convergence, calmness, removing toxic substances, analgesic effect; Rich in new element, the vigor of mankind spermatozoon can be improved;
Radix Codonopsis: sweet in the mouth, has effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, anticancer, blood pressure lowering, anti-hypoxia, defying age, it is also possible to strengthen body immunity, improves the activity of superoxide dismutase, strengthens the ability eliminating free radical; With ginseng compatibility can invigorating the spleen to benefit the lung, promote the production of body fluid and nourish blood;
Partition in Fructus Juglandis: reinforcing the kindey to control nocturnal emission; Control seminal emission lingering diarrhea, gonorrhea, hematuria, incontinence of urine, metrorrhagia, leukorrhagia, dysentery;
Radix Polygoni Multiflori Preparata: having tonification essence and blood, nourishing the liver is calmed the nerves, bone and muscle strengthening, the effect of the crow palpus that reinforces the kidney;
Cordyceps: can the immunity of enhancing body, nourishing lung and kidney; Clinically to chronic cough of deficiency lung, asthma, hemoptysis of pulmonary tuberculosis, night sweat, soreness of waist and knee joint of suffering from a deficiency of the kidney, impotence and seminal emission, neurasthenia and the red blood cell decreased after chemotherapy, radiotherapy are all effective in cure;
Herba Dendrobii: reinforcing stomach reg fluid, nourishing YIN and clearing away heat. Losing for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision; Record according to " herbal classic ", the main damaging the spleen and stomach of Herba Dendrobii, eliminating impediment, the therapeutic method to keep the adverse QI flowing downwards, tonifying five ZANG-organs asthenia weakness and emaciation, reinforcing YIN-essence, for a long time the thick the intestines and stomach of clothes;
Radix Glycyrrhizae: there is many-sided effects such as invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, eliminating fire and detoxication, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The present invention is the kidney invigorating gas with Herba Epimedii, Herba Cistanches, Penis et testis cervi, Cornu Cervi Pantotrichum, Gecko, Gecko hero testis, Hippocampus, Herba Cynomorii, Eurycoma longifolia, Radix Polygoni Multiflori Preparata, Partition in Fructus Juglandis and Cordyceps, supports the principal agent of essence and blood, tonifying YANG, assistant is with the Hirudo Activating stasis of blood, help and improve motility of sperm with Concha Ostreae, help with Radix Ginseng, Radix Codonopsis, Cordyceps, Herba Dendrobii and Radix Glycyrrhizae invigorating the spleen and replenishing QI, hold up this solid just, enhancing immunity, the present invention reasonable compatibility by said medicine, reaches the purpose of building body, kidney invigorating and YANG supporting, raising body immunity.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described, but protection scope of the present invention is not limited to following example:
One, the preparation of Traditional Chinese medicine composition for invigorating kidney and strengthening yang
Embodiment 1
Traditional Chinese medicine composition for invigorating kidney and strengthening yang, is mainly made up by weight ratio of following components: Hirudo 12 parts, Herba Epimedii 105, Herba Cistanches 22 parts, Penis et testis cervi 25 parts, 10 parts of Cornu Cervi Pantotrichum, Gecko 23 parts, Gecko hero testis 4 parts, Radix Ginseng 23 parts, Hippocampus 23 parts, Herba Cynomorii 19 parts, Eurycoma longifolia 8 parts, Concha Ostreae 24 parts, Radix Codonopsis 35 parts, Partition in Fructus Juglandis 2 parts, Radix Polygoni Multiflori Preparata 4 parts, Cordyceps 8 parts, Herba Dendrobii 13 parts, 31 parts of Radix Glycyrrhizae.
The preparation method of aforementioned pharmaceutical compositions is:
(1) said components is weighed by weight;
(2) Cornu Cervi Pantotrichum, Radix Ginseng and Cordyceps grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus and Radix Polygoni Multiflori Preparata, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Partition in Fructus Juglandis, Herba Dendrobii and Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder, Cordyceps powder and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Embodiment 2
Traditional Chinese medicine composition for invigorating kidney and strengthening yang, is mainly made up by weight ratio of following components: Hirudo 5 parts, Herba Epimedii 80 parts, Herba Cistanches 15 parts, Penis et testis cervi 20 parts, 8 parts of Cornu Cervi Pantotrichum, Gecko 18 parts, Gecko hero testis 2 parts, Radix Ginseng 15 parts, Hippocampus 15 parts, Herba Cynomorii 12 parts, Eurycoma longifolia 5 parts, Concha Ostreae 15 parts, Radix Codonopsis 30 parts, Partition in Fructus Juglandis 1 part, Radix Polygoni Multiflori Preparata 2 parts, Cordyceps 3 parts, Herba Dendrobii 10 parts, 22 parts of Radix Glycyrrhizae.
The preparation method of aforementioned pharmaceutical compositions is:
(1) said components is weighed by weight;
(2) Cornu Cervi Pantotrichum, Radix Ginseng and Cordyceps grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus and Radix Polygoni Multiflori Preparata, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Partition in Fructus Juglandis, Herba Dendrobii and Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder, Cordyceps powder and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Embodiment 3
Traditional Chinese medicine composition for invigorating kidney and strengthening yang, is mainly made up by weight ratio of following components: Hirudo 20 parts, Herba Epimedii 110 parts, Herba Cistanches 28 parts, Penis et testis cervi 30 parts, 12 parts of Cornu Cervi Pantotrichum, Gecko 28 parts, Gecko hero testis 6 parts, Radix Ginseng 30 parts, Hippocampus 28 parts, Herba Cynomorii 25 parts, Eurycoma longifolia 12 parts, Concha Ostreae 30 parts, Radix Codonopsis 40 parts, Partition in Fructus Juglandis 3 parts, Radix Polygoni Multiflori Preparata 6 parts, Cordyceps 10 parts, Herba Dendrobii 15 parts, 36 parts of Radix Glycyrrhizae.
The preparation method of aforementioned pharmaceutical compositions is:
(1) said components is weighed by weight;
(2) Cornu Cervi Pantotrichum, Radix Ginseng and Cordyceps grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus and Radix Polygoni Multiflori Preparata, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Partition in Fructus Juglandis, Herba Dendrobii and Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder, Cordyceps powder and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Two, clinical practice
1, the selection of case:
Select impotence patient, through 90 example clinical observations.
(1) inclusive criteria:
A. there are spouse male, 48 years old mean age at the age between 30-60 year.
B. tcm diagnosis impotence patient is standard: during between twenty and fifty man's sexual intercourse, owing to penis can not erect effectively, and causes more than the 75% of sexual intercourse plan and can not carry out, namely diagnosable for sexual impotence.
C. without organic disease.
C. can partner treatment, the patient of further consultation on time.
(2) exclusion standard
A. the age is below 30 years old or more than 60 years old person.
B. the organic impotence patient made a definite diagnosis.
C. severe primary disease and spirit, the psychotics such as cardiovascular, liver, kidney and hemopoietic system it are associated with.
D. allergic constitution or to multi-medicament allergy sufferers.
E. not by regulation medication or therapy discontinued, it is impossible to judge curative effect or data is not congruent affects the treatment or safety judgement person.
2, clinical trial:
(1) therapeutic scheme:
A. treatment group: by above-mentioned embodiment 1 ~ 3 sample prepared, for clinical trial. Oral, one time 2,3 times on the one. The course for the treatment of: medication 45 days.
B. matched group: NANBAO JIAONANG (commercially available). Oral, one time 3,2 times on the one. The course for the treatment of: medication 45 days.
(2) efficacy determination:
A. effective: erection > 90 after treatment, more than the 50% of sexual intercourse chance can success.
B. effective: after treatment, erection makes moderate progress, more than the 25% of sexual intercourse chance can success.
C. invalid: before and after medication, indices is all without improving.
(3) result of the test:
For treating 150 example outpatients. By the above-mentioned embodiment 1 prepared and NANBAO JIAONANG, it is respectively used to patient: treatment group: 90 examples, takes the capsule of embodiment 1 ~ 3, matched group: 30 examples. During clinical trial, withdraw other medicines and health nutrient. The results detailed in following table:
Group | Effective | Effectively | Invalid | Effective percentage |
Embodiment 1 | 13 | 12 | 5 | 83.3% |
Embodiment 2 | 12 | 12 | 7 | 76.6% |
Embodiment 3 | 12 | 12 | 6 | 80.0% |
Matched group | 12 | 11 | 7 | 76.6% |
Result shows: the effective percentage of embodiment 1 reaches 83.3%, is better than matched group; The effect of embodiment 2,3 is suitable with matched group. Patient is after treatment, it is common to reaction can improve the symptom of myasthenia of limbs, impotence and premature ejaculation.
Claims (5)
1. a Traditional Chinese medicine composition for invigorating kidney and strengthening yang, it is characterised in that it is mainly made up by weight ratio of following components:
Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 5 ~ 12 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 30 ~ 40 parts, Partition in Fructus Juglandis 1 ~ 3 part, Radix Polygoni Multiflori Preparata 2 ~ 6 parts, Cordyceps 6 ~ 10 parts, Herba Dendrobii 10 ~ 15 parts, 22 ~ 36 parts of Radix Glycyrrhizae.
2. Traditional Chinese medicine composition for invigorating kidney and strengthening yang according to claim 1, it is characterised in that it is mainly made up by weight ratio of following components:
Hirudo 12 parts, Herba Epimedii 105, Herba Cistanches 22 parts, Penis et testis cervi 25 parts, 10 parts of Cornu Cervi Pantotrichum, Gecko 23 parts, Gecko hero testis 4 parts, Radix Ginseng 23 parts, Hippocampus 23 parts, Herba Cynomorii 19 parts, Eurycoma longifolia 8 parts, Concha Ostreae 24 parts, Radix Codonopsis 35 parts, Partition in Fructus Juglandis 2 parts, Radix Polygoni Multiflori Preparata 4 parts, Cordyceps 8 parts, Herba Dendrobii 13 parts, 31 parts of Radix Glycyrrhizae.
3. Traditional Chinese medicine composition for invigorating kidney and strengthening yang according to claim 1 and 2, it is characterised in that:
Described pharmaceutical composition adds customary adjuvant by practice of pharmacy and makes any dosage form of clinical acceptance.
4. Traditional Chinese medicine composition for invigorating kidney and strengthening yang according to claim 3, it is characterised in that:
Described dosage form is capsule.
5. the preparation method of Traditional Chinese medicine composition for invigorating kidney and strengthening yang according to claim 1, it is characterised in that comprise the following steps:
(1) following component is weighed by weight: Hirudo 5 ~ 20 parts, Herba Epimedii 80 ~ 110 parts, Herba Cistanches 15 ~ 28 parts, Penis et testis cervi 20 ~ 30 parts, 8 ~ 12 parts of Cornu Cervi Pantotrichum, Gecko 18 ~ 28 parts, Gecko hero testis 2 ~ 6 parts, Radix Ginseng 15 ~ 30 parts, Hippocampus 15 ~ 28 parts, Herba Cynomorii 12 ~ 25 parts, Eurycoma longifolia 5 ~ 12 parts, Concha Ostreae 15 ~ 30 parts, Radix Codonopsis 30 ~ 40 parts, Partition in Fructus Juglandis 1 ~ 3 part, Radix Polygoni Multiflori Preparata 2 ~ 6 parts, Cordyceps 6 ~ 10 parts, Herba Dendrobii 10 ~ 15 parts, 22 ~ 36 parts of Radix Glycyrrhizae;
(2) Cornu Cervi Pantotrichum, Radix Ginseng and Cordyceps grind into powder respectively;
(3) Hirudo, Penis et testis cervi, Gecko, Gecko hero testis, Hippocampus and Radix Polygoni Multiflori Preparata, adding 4 ~ 6 times of weight concentrations of above-mentioned each component weight is the ethanol of 70 ~ 80%, heating and refluxing extraction 2 ~ 3 times, each 2 ~ 5 hours, gradation filtered, merging filtrate, concentration, reclaims ethanol, obtains concentrated solution A; Standby;
(4) Herba Epimedii, Herba Cistanches, Herba Cynomorii, Eurycoma longifolia, Concha Ostreae, Radix Codonopsis, Partition in Fructus Juglandis, Herba Dendrobii and Radix Glycyrrhizae, add the water of above-mentioned 6 ~ 10 times of weight of each component weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, gradation filtered, merging filtrate, add concentrated solution A, be condensed into thick paste, add Pilose Antler, Radix Ginseng powder, Cordyceps powder and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(5) take dried cream powder and add starch slurry, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610075517.6A CN105641466A (en) | 2016-02-03 | 2016-02-03 | Traditional Chinese medicine composition for invigorating kidney and strengthening yang and preparing method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610075517.6A CN105641466A (en) | 2016-02-03 | 2016-02-03 | Traditional Chinese medicine composition for invigorating kidney and strengthening yang and preparing method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105641466A true CN105641466A (en) | 2016-06-08 |
Family
ID=56488310
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610075517.6A Pending CN105641466A (en) | 2016-02-03 | 2016-02-03 | Traditional Chinese medicine composition for invigorating kidney and strengthening yang and preparing method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105641466A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108294307A (en) * | 2018-01-17 | 2018-07-20 | 上海茂久中医药科技有限公司 | A kind of nutriment containing testis Gallus domesticu, cockscomb, Herba Epimedii |
CN108295197A (en) * | 2018-04-09 | 2018-07-20 | 王凯 | A kind of medicinal liquor for strengthening yang and preparation method thereof |
CN114190504A (en) * | 2021-12-15 | 2022-03-18 | 哈尔滨健领医疗科技有限公司 | Solid beverage capable of warming and invigorating kidney yang and preparation method thereof |
CN114984076A (en) * | 2022-06-30 | 2022-09-02 | 王杰 | Navel dropping liquid for tonifying kidney and improving immunity and preparation and application methods thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105233010A (en) * | 2015-11-13 | 2016-01-13 | 关玉斌 | Wine capable of invigorating kidney and strengthening Yang and making method thereof |
-
2016
- 2016-02-03 CN CN201610075517.6A patent/CN105641466A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105233010A (en) * | 2015-11-13 | 2016-01-13 | 关玉斌 | Wine capable of invigorating kidney and strengthening Yang and making method thereof |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108294307A (en) * | 2018-01-17 | 2018-07-20 | 上海茂久中医药科技有限公司 | A kind of nutriment containing testis Gallus domesticu, cockscomb, Herba Epimedii |
CN108295197A (en) * | 2018-04-09 | 2018-07-20 | 王凯 | A kind of medicinal liquor for strengthening yang and preparation method thereof |
CN114190504A (en) * | 2021-12-15 | 2022-03-18 | 哈尔滨健领医疗科技有限公司 | Solid beverage capable of warming and invigorating kidney yang and preparation method thereof |
CN114984076A (en) * | 2022-06-30 | 2022-09-02 | 王杰 | Navel dropping liquid for tonifying kidney and improving immunity and preparation and application methods thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103520654B (en) | A kind of Chinese medicine composition being used for the treatment of knee osteoarthritis and preparation method thereof | |
CN105641466A (en) | Traditional Chinese medicine composition for invigorating kidney and strengthening yang and preparing method thereof | |
CN104825914A (en) | Traditional Chinese medicinal preparation for assisted treatment of breast cancer | |
CN101129878A (en) | Traditional Chinese medicine preparation for treating uterine prolapse | |
CN104069474A (en) | Traditional Chinese medicine composition for treating seborrheic alopecia and preparation method thereof | |
CN105641330A (en) | Traditional Chinese medicine composition for invigorating kidney and strengthening yang | |
CN105641060A (en) | Medicine composition with body building and yang tonifying functions | |
CN105232987A (en) | Traditional Chinese medicine promoting neurosurgery postoperative rehabilitation | |
CN104274630A (en) | Formula of traditional Chinese medicine for preventing hair loss and promoting hair growth and preparation method thereof | |
CN103585596B (en) | Traditional Chinese medicine composition for treating migraine | |
CN105617388A (en) | Kidney-tonifying yang-strengthening medicine composition | |
CN105663383A (en) | Traditional Chinese medicine composition with body building and yang strengthening functions | |
CN105250959A (en) | Traditional Chinese medicine preparation for repairing liver damage and preparation method | |
CN105664143A (en) | Medicinal composition with body building and yang strengthening functions and preparation method thereof | |
CN104998074A (en) | Traditional Chinese medicine for treating gastropathy and preparation method thereof | |
CN104840902A (en) | Traditional Chinese medicine preparation for treating ovarian tumor | |
CN104857370A (en) | Traditional Chinese medicine composition for treating breast cancer | |
CN104257986A (en) | Traditional Chinese medicine for treating nephritis | |
CN103961555A (en) | Traditional Chinese medicine preparation for treating peripheral nerve injury and preparation method thereof | |
CN103463463A (en) | Traditional Chinese medicine preparation for replenishing and activating blood and dispelling wind and removing dampness | |
CN107412679A (en) | Detoxifying health-care product and its preparation method and application | |
CN105521391A (en) | Traditional Chinese medicine for tonifying liver and kidney and for strengthening bones and muscles and preparation method of traditional Chinese medicine | |
CN104840814A (en) | Traditional Chinese medicine combination for treating senile femoral head necrosis | |
CN104758889A (en) | Traditional Chinese medicine composition for treating diabetes | |
CN104189608A (en) | Traditional Chinese medicine preparation for treating recurrent oral ulceration and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160608 |