CN104189608A - Traditional Chinese medicine preparation for treating recurrent oral ulceration and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating recurrent oral ulceration and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating the recurrent oral ulceration and a preparation method thereof and belongs to the field of traditional Chinese medicines. Active ingredients of the traditional Chinese medicine preparation disclosed by the invention comprise the following raw materials in parts by weight: radix cynanchi bungei, gynura bicolor 81, serrate clubmoss herb, hemlock chervil, root of velutinous indigo, euphorbia humifusa, purpleflower holly fruit, catechu, chorion ovi, Chinese wingnut leaf, adina pilulifera, the root of bidentate achyranthes, Chinese incarvilla herb, bog rush, mulberry silkworm egg shell and bitter bamboo leaf. The traditional Chinese medicine preparation disclosed by the invention is prepared by selecting the traditional Traditional Chinese medicine material components with effects of clearing heat and removing toxicity, healing sore and stopping bleeding, diminishing inflammation and swelling, promoting blood circulation and stopping pain, is proper in compatibility, has effects of activating blood and diminishing swelling, stopping bleeding and promoting tissue regeneration and clearing heat and relieving restlessness, is convenient to use, has a good absorption effect, has no bad and toxic or side effects, has excellent effects on relieving and treating the recurrent oral ulceration by clinical verification and is suitable for clinical treatment and nursing of the recurrent oral ulceration, popularization and application.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation and preparation method for the treatment of recurrent oral ulceration.
Background technology
Recurrent oral ulceration claims again recurrent aphtha, recurrent aphthous stomatitis, recurrent aphtha, it is the highest a kind of disease of sickness rate in oral mucosa disease, common cold, dyspepsia, psychentonia, the gloomy situation such as discomfort all can accidentally cause the generation of this disease, be apt to occur in lip, cheek, lingual margin etc., any position at mucosa all can occur, but keratinization completely attached gingiva and hard palate rare.Age of onset is generally between 10～30 years old, and women is more, all can occur throughout the year.
Recurrent aphtha has self limiting, can be left and right spontaneous recovery in 10 days, there is the features such as periodicity, recurrent and self limiting, but can recur again after the intermission different in size, can be divided into light-duty recurrent oral ulceration, herpesvirus type recurrent oral ulceration and heavy recurrent oral ulceration.
Light-duty recurrent oral ulceration is from the beginning of lesion sensitivity or occur needle point sample size or slightly large congested district, forms in a short time diameter in 2～4mm left and right, circular or oval, sharply marginated shallow aphtha.Center micro-pits, surface is covered with the faint yellow pseudomembrane of one deck, and ulcer mucosa hyperemia is around blush shape, and it is not hard that lay one's hand at its end.Ulcer number is generally 2～3 left and right.After ulcer, there is more violent burning pain.Through left and right ulcer spontaneous recovery gradually in 7～10 days, do not stay cicatrix.But can recur again after the intermission different in size.
Herpesvirus type recurrent oral ulceration also claims stomatitis type aphtha.This kind of is except ulcer is little, number many (can reach 20～30), and all the other are similar to light-duty recurrent recurrent oral ulceration performance.KUIYANG SAN exists, widely distributed, and mucosa is obviously congested.Have an intense pain and with headache, heating, regional glandular enlargement etc.
Heavy recurrent oral ulceration also claims recurrent gangrenosum acne mucosa periadenitis or periglandular aphthae, is a type the most serious in various.The normal single generation of ulcer, more than 2 or 2 person is rare.Be apt to occur in lip inner side and bicker district mucosa.From the beginning of time ulcer identical with light-duty recurrent oral ulceration, ulcer is aubergine or kermesinus, edge is irregular, is flap protuberance, concavity, like " crater ".End injustice, micro-hard, be brief summary nodular, ulcer is blush around, part has an intense pain and can accompany regional glandular enlargement, heating etc.The course of disease be everlasting month remaining more than.Leave over more afterwards cicatrix, severe patient is can formative tissue damaged or lopsided.
Recurrent oral ulceration can multiple complications, and its harm should not be underestimated.Be used for the treatment of at present the medicine of recurrent oral ulceration disease mainly with anti-inflammation, antiallergic, local anesthesia pain relieving class medicine is made, but this type for the treatment of has certain side effect and dependency, therefore treat the necessary safety of medicine of recurrent oral ulceration, effectively, have no side effect, and Chinese materia medica is as the traditional medicine of China, there is effect strong, instant effect, the advantages such as lasting medicine, and there is no dependency, drug resistance and toxic and side effects, therefore select a kind of Chinese medicine preparation treatment recurrent oral ulceration, there is very important clinical meaning for treatment recurrent oral ulceration.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method that is used for the treatment of recurrent oral ulceration; The Chinese crude drug prescription of the selected heat-clearing and toxic substances removing of Chinese medicine preparation of the present invention, sore hemostasis, anti-inflammation detumescence, promoting blood circulation and stopping pain is concocted, compatibility is suitable, there is effect of promoting blood circulation and detumescence, hemostasia and promoting granulation, clearing heat and relieving fidgetness, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, recurrent oral ulceration is had to fabulous alleviation and therapeutic effect, be suitable for recurrent oral ulceration clinical treatment and nursing and apply.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for recurrent oral ulceration, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of recurrent oral ulceration, comprise following processing step:
(1) Radix Cynanchi Auriculati, hemlock chervil, Radix indigoferae stachyoidis, Ramulus et Folium Adinae Piluliferae and Radix Achyranthis Bidentatae are put to decontamination, be placed in container, add the distilled water of 8～10 times of amounts, soak after 4～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 1～3 hour, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, for subsequent use;
(2) get Herba Gynurae bicoloris, catechu and Crusta Bombycis ovum decontamination, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) after Herba Lycopodii serrati, Radix seu Caulis Parthenocissi tricuspidatae, Membrana Follicularis ovi and Herba Incarvilleae sinensis being stir-fried with high heat for several times, surface uniform sprays yellow wine, after fried dry, pulverizes, and grinds into powder, crosses 180 order fine powders, for subsequent use;
(4) get Fructus Ilicis Purpureae, Folium pterocaryae stenopterae, Medulla Junci and Folium Pleioblasti saline and mix thoroughly vexedly, with the micro-stir-fry of little fire, taking-up is dried, and is placed in mortar and grinds into powder, crosses 200 order fine powders, for subsequent use;
(5) by the filtrate of step (1) gained, mix with the fine powder of step (4) gained with step (2), step (3), make buccal tablet, be the Chinese medicine preparation for the treatment of recurrent oral ulceration of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Cynanchi Auriculati: bitter in the mouth, sweet, puckery, slightly warm in nature; Return liver,kidney,spleen stomach warp.Invigorating the liver and kidney, bone and muscle strengthening, benefiting essence-blood, strengthening the spleen to promote digestion, detoxification sore treatment.For soreness of the waist and knees, impotence and seminal emission, dizziness and tinnitus, palpitation and insomnia, inappetence, infantile malnutrition, puerperal milk rareness, sore, carbuncle and painful swelling." Shandong Chinese medicine " carries: " be nourishing, strong, hematonic, and can restrain vital essence, crow must hair color.Control prolonged illness weakness, anemia, early whitening of beard and hair, chronic migratory arthralgia, soreness of the waist and knees, sexual neurasthenie, hemorrhoid, enterorrhagia, deficiency of YIN chronic malaria, ulcer does not close up for a long time.Fresh and have the effect of loosening bowel to relieve constipation, be applicable to old man's constipation.”
Herba Gynurae bicoloris: taste is micro-sweet, pungent, property is flat.Clearing away heat and cooling blood, removing toxic substances disappears.For hemoptysis, metrorrhagia, traumatic hemorrhage, dysmenorrhea, dysentery, sore swollen toxin, traumatic injury, ulcer does not restrain for a long time." Fujian Chinese herbal medicine " carries: " hemopoietic hemostasis, clearing heat for detumescence.”
Herba Lycopodii serrati: bitter in the mouth, micro-sweet, property is flat; Return lung, large intestine, liver, kidney channel, slightly poisonous.Heat-clearing and toxic substances removing, eliminating dampness and astringing sores, hemostasis analgesic therapy, dissipating blood stasis for subsidence of swelling.For pneumonia, over-strained hemoptysis, hemorrhoidal hemorrhage, traumatic injury, toxic swelling, water hygral expansion, ulcer does not close up for a long time." conventional Chinese herbal medicine formula " carries: " hemostasis of bringing down a fever, reducing swelling and alleviating pain.Control lung-heat and spit blood, abscess, festers, wound disunion of a specified duration.”
Hemlock chervil: bitter in the mouth, pungent, slightly warm in nature; Return spleen, large intestine channel, slightly poisonous.Promoting blood circulation and detumescence, convergence parasite killing.For chronic diarrhea, ascariasis, carbuncle sore does not close up for a long time, trichomonas vaginitis.
Radix indigoferae stachyoidis: sweet in the mouth, hardship, warm in nature; Return liver, kidney, large intestine channel.Tonify deficiency, invigorates blood circulation, Gu de-.For metrorrhagia, chronic dysentery, traumatic injury, rheumatism, ulcer does not close up for a long time." Yunnan Chinese herbal medicine " carries: " promoting blood circulation and stopping pain, relaxing muscles and tendons and activating QI and blood in the collateral.Control metrorrhagia, traumatic injury, rheumatism, liver cirrhosis, infantile malnutrition, dysentery.”
Radix seu Caulis Parthenocissi tricuspidatae: acrid in the mouth, micro-puckery, warm in nature; Return Liver Channel.Wind-expelling pain-stopping, promoting blood circulation to remove obstruction in the collateral.For rheumatic arthralgia, apoplexy and hemiplegia, migraine and general headache, puerperal blood stasis, the raw caking of abdomen, traumatic injury, carbuncle sore tumefacting virus, ulcer being unable to heal." Zhejiang conventional medical herbs among the people " carries: " wind-damp dispelling, the meridian dredging, hemostasis.”
Fructus Ilicis Purpureae: bitter in the mouth, sweet, cool in nature; Return liver, kidney channel.Invigorating the liver and kidney, curing rheumatism, arresting bleeding and healing up ulcer.For early whitening of beard and hair, wind shows arthralgia pain, digestive ulcerative bleeding, hemorrhoid, ulcer being unable to heal.
Catechu: bitter in the mouth, puckery, cold nature; Return lung meridian.Removing heat-phlegm, sore hemostasis.For cough due to lung-heat, diarrhoea, infantile dyspepsia, skin infection does not close up for a long time, skin eczema, aphtha, tonsillitis.
Membrana Follicularis ovi: sweet in the mouth, light, warm in nature.Nourishing YIN and clearing away lung-heat, sore removing nebula, synthetism.For coughing asthma, pharyngalgia aphonia, lymphoid tuberculosis outward; Ulcer being unable to heal; The raw cataracta of order, the vertigo, trauma fracture." classification medical herbs " carries: " control infantile convulsion belly pain; Forge and grind painting skin ulcer, rawhide.”
Folium pterocaryae stenopterae: acrid in the mouth, hardship, warm in nature, poisonous; Return lung, Liver Channel.Wind-expelling pain-stopping, killing parasites for relieving itching, removing toxic substances sore.For rheumatic arthralgia, knee-joint pain, vagina wound, ulcer being unable to heal; Cough and asthma." Traditional Chinese Medicine in Sichuan will " carries: " parasite killing, removing toxic substances.Be coated with burn and skin ulcer, only toothache for a long time.”
Ramulus et Folium Adinae Piluliferae: bitter in the mouth, property is flat.Clearing away heat-damp and promoting diuresis, repercussive analgesic therapy, hemostasia and promoting granulation.For dysentery, enteritis, damp and hot edema, carbuncle sore tumefacting virus, eczema, rotten foot, ulcer being unable to heal, wound hemorrhage." Luchuan book on Chinese herbal medicine " carries: " eliminating inflammation and expelling toxin removing the necrotic tissue.Control skin infections poison, carbuncle sore ulceration.”
Radix Achyranthis Bidentatae: bitter in the mouth, acid, property is flat; Return liver, kidney channel.Dissipating blood stasis blood, subduing inflammation.For gonorrhea hematuria, amenorrhea lump in the abdomen, difficult labour, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury." detailed outline " carries: " control chronic malaria cold and heat, five types of stranguria hematuria, pains in the penis, dysentery, sore throat, aphtha, toothache, carbuncle malignant boil, traumatics fracture.”
Herba Incarvilleae sinensis: bitter in the mouth, sweet, warm in nature; Return liver,spleen,kidney warp.Wind-damp dispelling, removing toxic substances parasite killing.For aphtha, gums festers, inflammation of external auditory meatus, eczema, scabies, trichomonal vaginitis.
Medulla Junci: sweet in the mouth, light, cold nature; GUIXIN, lung, small intestine meridian.Clearing away heart-fire, diuresis.For vexed insomnia, the puckery pain of oliguria, aphtha of the mouth and tongue." the conventional Chinese herbal medicine handbook in the north " carries: " heat clearing and tranquillizing, relieving stranguria by diuresis.”
Crusta Bombycis ovum: sweet in the mouth, property is flat; Return liver, heart channel.Hemostasis, dysentery relieving, removing toxic substances and promoting subsidence of swelling.For hematemesis and epistaxis, metrorrhagia, perianal abscess hematochezia, dysentery, swelling throat numbness, ulcerative gingivitis aphtha.
Folium Pleioblasti: sweet in the mouth, light, cold in nature; Return liver, the heart, lung meridian.Clearing heat and relieving fidgetness, the diuresis of quenching one's thirst.Thirsty for fever and irritability, aphtha of the mouth and tongue, oliguria yellow skin." not Lu " carries: " treat aphtha, ophthalmalgia, improving eyesight, sharp nine orifices.”
The present invention compared with prior art, has following beneficial effect:
The Chinese crude drug prescription of the selected heat-clearing and toxic substances removing of Chinese medicine preparation of the present invention, sore hemostasis, anti-inflammation detumescence, promoting blood circulation and stopping pain is concocted, compatibility is suitable, there is effect of promoting blood circulation and detumescence, hemostasia and promoting granulation, clearing heat and relieving fidgetness, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, recurrent oral ulceration is had to fabulous alleviation and therapeutic effect, be suitable for recurrent oral ulceration clinical treatment and nursing and apply.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) Radix Cynanchi Auriculati, hemlock chervil, Radix indigoferae stachyoidis, Ramulus et Folium Adinae Piluliferae and Radix Achyranthis Bidentatae are put to decontamination, be placed in container, add the distilled water of 8～10 times of amounts, soak after 4～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 1～3 hour, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, for subsequent use;
(2) get Herba Gynurae bicoloris, catechu and Crusta Bombycis ovum decontamination, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) after Herba Lycopodii serrati, Radix seu Caulis Parthenocissi tricuspidatae, Membrana Follicularis ovi and Herba Incarvilleae sinensis being stir-fried with high heat for several times, surface uniform sprays yellow wine, after fried dry, pulverizes, and grinds into powder, crosses 180 order fine powders, for subsequent use;
(4) get Fructus Ilicis Purpureae, Folium pterocaryae stenopterae, Medulla Junci and Folium Pleioblasti saline and mix thoroughly vexedly, with the micro-stir-fry of little fire, taking-up is dried, and is placed in mortar and grinds into powder, crosses 200 order fine powders, for subsequent use;
(5) by the filtrate of step (1) gained, mix with the fine powder of step (4) gained with step (2), step (3), make buccal tablet, be the Chinese medicine preparation for the treatment of recurrent oral ulceration of the present invention.
Usage and dosage: oral, every day 3 times, the morning, noon and afternoon, respectively once each 15 days was a course for the treatment of, and common 2～5 courses for the treatment of are effective, severe patient is followed the doctor's advice and is drunk the amount of adding.
Embodiment 2
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
The routine clinical observation of Blood of Patients with Recurrent Oral 300 of selecting my institute or outer court to make a definite diagnosis, patient is divided into two groups at random, treatment group 150 examples, wherein male's 75 examples, women's 75 examples, 9～52 years old age, 25 years old mean age, the course of disease 3 days～60 days, average 10 days.Matched group 150 examples, wherein male's 72 examples, women's 78 examples, 12～45 years old age, 28 years old mean age, the course of disease 1 day～36 days, average 7 days.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes Chinese medicine preparation of the present invention, oral, and every day 3 times, the morning, noon and afternoon, respectively once each 15 days was a course for the treatment of, common 2～5 onsets course for the treatment of, and severe patient is followed the doctor's advice and is drunk the amount of adding.
Matched group patient is coated with gentamycin: dip ulcer surface in injection liquid of gentamicin dab oral cavity with disinfecting cotton swab, repaste once after several minutes, every day 4 times, three after the meal and before sleeping, and after gargling, coats medicinal liquid.
3, efficacy determination:
(1) cure: oral cavity bleeding blister, mouth burning tongue, oral mucosa fills the air congested grade for transference cure; The activity of mouth tongue freely, in high spirits.
(2) effective: above-mentioned symptom is alleviated to some extent, and the activity of mouth tongue freely, in high spirits.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, cure 107 examples, effective 29 examples, invalid 14 examples, cure rate 71.3%, total effective rate 90.7%.
In matched group, cure 84 examples, effective 34 examples, invalid 32 examples, cure rate 56%, total effective rate 78.6%.
Above result demonstration, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is given an example:
1, sternly × ×, man, 10 years old, student, people from Chengdu, Sichuan.Patient suffers from oral ulcer, cries and screams more than, cannot normally take food.Take after 2 courses for the treatment of of Chinese medicine preparation of the present invention, above symptom is obviously alleviated, continue to take after 3 courses for the treatment of, and mouth burning tongue, oral mucosa fills the air congested grade for transference cure, and activity is freely.Follow up a case by regular visits to not recurrence so far.
2, gold × ×, man, 17 years old, student, people from Xining, Qinghai.Patient's oral mucosa is extensively congested, dry mouth and parching tongue, and two cheek rednesses, erosion, be diagnosed as recurrent oral ulceration.Take after 2 courses for the treatment of of Chinese medicine preparation of the present invention, above symptom is clearly better, and continues to strengthen after 2 courses for the treatment of of treatment, and it is normal that oral cavity function recovers, and activity freely.Follow up a case by regular visits to not recurrence so far.
3, Wei × ×, female, 21 years old, student, the new village people in Hebei.There is aphtha in right side, buccal, patient oral cavity, dysphoria and insomnia, and complexion is sent out red, detests hydraulic fluid port greasy, and slightly unsatisfactory is anger, red tongue, yellow fur is thick, is diagnosed as recurrent oral ulceration.Take after 2 courses for the treatment of of Chinese medicine preparation of the present invention, symptom takes a turn for the better, continue to take after 3 courses for the treatment of, and transference cure, activity is freely.Follow up a case by regular visits to not recurrence.
4, pottery × ×, female, 28 years old, Enterprise Staff, ShaoXing,ZheJiang people.Mucosa many places ulcer in patient's mouth, successively once failed to cure at many hospital therapies, and recurrence often increases the weight of, and had affected work and life.Take after 3 courses for the treatment of of Chinese medicine preparation of the present invention, symptom disappears completely, and freely, livelihood restoration is normal in activity.Follow up a case by regular visits to not recurrence so far.
5, Rhizoma Zingiberis Recens × ×, female, 35 years old, trainer, Gansu the Jiayu Pass people.The two cheek erosions of patient oral cavity, pain, dry mouth and parching tongue, oral mucosa is extensively congested, and two cheek posterior segment large area present greyish white ring-like netted, and wax sample disease damage and companion's redness, erosion, pus tongue and sepage, attach most importance to left side.Take after 3 courses for the treatment of of Chinese medicine preparation of the present invention, above symptom takes a turn for the better, continue to take after 2 courses for the treatment of, activity freely, not recurrence.
6, relative × ×, man, 46 years old, peasant, people from Jingmen, Hubei.Respectively there is aphtha in Ji Shezhi both sides, right side, buccal, patient oral cavity, dysphoria and insomnia, and complexion is sent out red, self-induction palpitating speed, bitter taste lack of appetite, detests hydraulic fluid port greasy, and slightly unsatisfactory is anger, constipation with dry stool, red tongue, yellow fur is thick, and arteries and veins flood is sliding etc.Take Chinese medicine preparation of the present invention, after 2 courses for the treatment of, symptom obviously alleviates, and continues to take after 2 courses for the treatment of, and physical recovery is normal.
Claims (5)
1. a Chinese medicine preparation for the treatment of recurrent oral ulceration, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
55～85 parts of 57～87 parts of hemlock chervils of 59～89 parts of Herba Lycopodii serratis of 62～92 parts of Herba Gynurae bicoloris of Radix Cynanchi Auriculati
42～72 parts of 47～77 parts of Fructus Ilicis Purpureaes of 52～82 portions of Radix seu Caulis Parthenocissi tricuspidataes of Radix indigoferae stachyoidis, 44～74 share tea
33～63 parts of 35～65 parts of Radix Achyranthis Bidentataes of 37～67 parts of Ramulus et Folium Adinae Piluliferaes of 40～70 parts of Folium pterocaryae stenopteraes of Membrana Follicularis ovi
22～52 parts of 27～57 parts of Folium Pleioblastis of 28～58 parts of Crusta Bombycis ovums of 32～62 portions of Medulla Juncies of Herba Incarvilleae sinensis.
2. a kind of Chinese medicine preparation for the treatment of recurrent oral ulceration according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
77 parts of 79 parts of hemlock chervils of 81 parts of Herba Lycopodii serratis of 84 parts of Herba Gynurae bicoloris of Radix Cynanchi Auriculati
64 parts of 69 parts of Fructus Ilicis Purpureaes of 74 portions of Radix seu Caulis Parthenocissi tricuspidataes of Radix indigoferae stachyoidis, 67 share tea
55 parts of 57 parts of Radix Achyranthis Bidentataes of 59 parts of Ramulus et Folium Adinae Piluliferaes of 63 parts of Folium pterocaryae stenopteraes of Membrana Follicularis ovi
44 parts of 49 parts of Folium Pleioblastis of 50 parts of Crusta Bombycis ovums of 54 portions of Medulla Juncies of Herba Incarvilleae sinensis.
3. a kind of Chinese medicine preparation for the treatment of recurrent oral ulceration according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
70 parts of 72 parts of hemlock chervils of 74 parts of Herba Lycopodii serratis of 77 parts of Herba Gynurae bicoloris of Radix Cynanchi Auriculati
57 parts of 62 parts of Fructus Ilicis Purpureaes of 67 portions of Radix seu Caulis Parthenocissi tricuspidataes of Radix indigoferae stachyoidis, 60 share tea
48 parts of 50 parts of Radix Achyranthis Bidentataes of 52 parts of Ramulus et Folium Adinae Piluliferaes of 56 parts of Folium pterocaryae stenopteraes of Membrana Follicularis ovi
37 parts of 42 parts of Folium Pleioblastis of 43 parts of Crusta Bombycis ovums of 47 portions of Medulla Juncies of Herba Incarvilleae sinensis.
4. a kind of Chinese medicine preparation for the treatment of recurrent oral ulceration according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
63 parts of 65 parts of hemlock chervils of 66 parts of Herba Lycopodii serratis of 70 parts of Herba Gynurae bicoloris of Radix Cynanchi Auriculati
50 parts of 55 parts of Fructus Ilicis Purpureaes of 60 portions of Radix seu Caulis Parthenocissi tricuspidataes of Radix indigoferae stachyoidis, 52 share tea
41 parts of 43 parts of Radix Achyranthis Bidentataes of 45 parts of Ramulus et Folium Adinae Piluliferaes of 46 parts of Folium pterocaryae stenopteraes of Membrana Follicularis ovi
30 parts of 35 parts of Folium Pleioblastis of 35 parts of Crusta Bombycis ovums of 40 portions of Medulla Juncies of Herba Incarvilleae sinensis.
5. a preparation method for the Chinese medicine preparation of the treatment recurrent oral ulceration as described in claim 1～4, is characterized in that: comprise following processing step:
(1) Radix Cynanchi Auriculati, hemlock chervil, Radix indigoferae stachyoidis, Ramulus et Folium Adinae Piluliferae and Radix Achyranthis Bidentatae are put to decontamination, be placed in container, add the distilled water of 8～10 times of amounts, soak after 4～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 1～3 hour, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, for subsequent use;
(2) get Herba Gynurae bicoloris, catechu and Crusta Bombycis ovum decontamination, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) after Herba Lycopodii serrati, Radix seu Caulis Parthenocissi tricuspidatae, Membrana Follicularis ovi and Herba Incarvilleae sinensis being stir-fried with high heat for several times, surface uniform sprays yellow wine, after fried dry, pulverizes, and grinds into powder, crosses 180 order fine powders, for subsequent use;
(4) get Fructus Ilicis Purpureae, Folium pterocaryae stenopterae, Medulla Junci and Folium Pleioblasti saline and mix thoroughly vexedly, with the micro-stir-fry of little fire, taking-up is dried, and is placed in mortar and grinds into powder, crosses 200 order fine powders, for subsequent use;
(5) by the filtrate of step (1) gained, mix with the fine powder of step (4) gained with step (2), step (3), make buccal tablet, be the Chinese medicine preparation for the treatment of recurrent oral ulceration of the present invention.
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| CN104888112A (en) * | 2015-05-22 | 2015-09-09 | 林艳 | Medicine for treating recurrent oral ulceration |
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| CN102139081A (en) * | 2011-03-11 | 2011-08-03 | 中国人民解放军总医院 | Chinese medicinal composition and preparation for treating recurrent oral ulcer and preparation method thereof |
| CN103223059A (en) * | 2013-03-22 | 2013-07-31 | 孙秀娟 | Traditional Chinese medicine for treating recurrent oral ulcer |
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2014
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102139081A (en) * | 2011-03-11 | 2011-08-03 | 中国人民解放军总医院 | Chinese medicinal composition and preparation for treating recurrent oral ulcer and preparation method thereof |
| CN103223059A (en) * | 2013-03-22 | 2013-07-31 | 孙秀娟 | Traditional Chinese medicine for treating recurrent oral ulcer |
Non-Patent Citations (2)
| Title |
|---|
| 李秀荣: "复发性口腔溃疡的临床诊治探析", 《吉林医学》, vol. 35, no. 1, 31 January 2014 (2014-01-31), pages 59 - 60 * |
| 王慈等: "中医药治疗复发性口腔溃疡研究近况", 《四川中医》, vol. 30, no. 12, 31 December 2012 (2012-12-31), pages 149 - 151 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104888112A (en) * | 2015-05-22 | 2015-09-09 | 林艳 | Medicine for treating recurrent oral ulceration |
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| CN104189608B (en) | 2015-02-25 |
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