CN107412679A - Detoxifying health-care product and its preparation method and application - Google Patents
Detoxifying health-care product and its preparation method and application Download PDFInfo
- Publication number
- CN107412679A CN107412679A CN201710709534.5A CN201710709534A CN107412679A CN 107412679 A CN107412679 A CN 107412679A CN 201710709534 A CN201710709534 A CN 201710709534A CN 107412679 A CN107412679 A CN 107412679A
- Authority
- CN
- China
- Prior art keywords
- parts
- care
- raw
- detoxifying health
- health
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 28
- 244000163122 Curcuma domestica Species 0.000 claims abstract description 38
- 235000003392 Curcuma domestica Nutrition 0.000 claims abstract description 38
- 235000003373 curcuma longa Nutrition 0.000 claims abstract description 38
- 235000013976 turmeric Nutrition 0.000 claims abstract description 38
- 231100000765 Toxin Toxicity 0.000 claims abstract description 25
- 239000003053 toxin Substances 0.000 claims abstract description 25
- 235000011201 Ginkgo Nutrition 0.000 claims abstract description 24
- 240000002883 Ginkgo biloba Species 0.000 claims abstract description 24
- 235000000381 ginkgo Nutrition 0.000 claims abstract description 24
- 240000002853 Nelumbo nucifera Species 0.000 claims abstract description 23
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims abstract description 23
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims abstract description 23
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 22
- 235000003097 Artemisia absinthium Nutrition 0.000 claims abstract description 21
- 240000001851 Artemisia dracunculus Species 0.000 claims abstract description 21
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims abstract description 21
- 240000002012 Lycium chinense Species 0.000 claims abstract description 21
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 21
- 239000001138 artemisia absinthium Substances 0.000 claims abstract description 21
- 235000009051 wormwood Nutrition 0.000 claims abstract description 21
- 235000017731 wormwood Nutrition 0.000 claims abstract description 21
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 19
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 19
- 235000005822 corn Nutrition 0.000 claims abstract description 19
- 235000005824 corn Nutrition 0.000 claims abstract description 19
- 235000005035 ginseng Nutrition 0.000 claims abstract description 19
- 235000008434 ginseng Nutrition 0.000 claims abstract description 19
- 125000003118 aryl group Chemical group 0.000 claims abstract description 18
- 210000003056 Antler Anatomy 0.000 claims abstract description 17
- 240000008397 Ganoderma lucidum Species 0.000 claims abstract description 16
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims abstract description 16
- 210000001320 Hippocampus Anatomy 0.000 claims abstract description 16
- 241000112528 Ligusticum striatum Species 0.000 claims abstract description 16
- 235000006484 Paeonia officinalis Nutrition 0.000 claims abstract description 16
- 235000006040 Prunus persica var persica Nutrition 0.000 claims abstract description 16
- 240000004678 Panax pseudoginseng Species 0.000 claims abstract description 15
- 244000144730 Amygdalus persica Species 0.000 claims abstract description 14
- 241000132012 Atractylodes Species 0.000 claims abstract description 14
- 240000008259 Paeonia officinalis Species 0.000 claims abstract 4
- 239000002994 raw material Substances 0.000 claims description 93
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound data:image/svg+xml;base64,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 data:image/svg+xml;base64,PD94bWwgdmVyc2lvbj0nMS4wJyBlbmNvZGluZz0naXNvLTg4NTktMSc/Pgo8c3ZnIHZlcnNpb249JzEuMScgYmFzZVByb2ZpbGU9J2Z1bGwnCiAgICAgICAgICAgICAgeG1sbnM9J2h0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnJwogICAgICAgICAgICAgICAgICAgICAgeG1sbnM6cmRraXQ9J2h0dHA6Ly93d3cucmRraXQub3JnL3htbCcKICAgICAgICAgICAgICAgICAgICAgIHhtbG5zOnhsaW5rPSdodHRwOi8vd3d3LnczLm9yZy8xOTk5L3hsaW5rJwogICAgICAgICAgICAgICAgICB4bWw6c3BhY2U9J3ByZXNlcnZlJwp3aWR0aD0nODVweCcgaGVpZ2h0PSc4NXB4JyB2aWV3Qm94PScwIDAgODUgODUnPgo8IS0tIEVORCBPRiBIRUFERVIgLS0+CjxyZWN0IHN0eWxlPSdvcGFjaXR5OjEuMDtmaWxsOiNGRkZGRkY7c3Ryb2tlOm5vbmUnIHdpZHRoPSc4NS4wJyBoZWlnaHQ9Jzg1LjAnIHg9JzAuMCcgeT0nMC4wJz4gPC9yZWN0Pgo8cGF0aCBjbGFzcz0nYm9uZC0wIGF0b20tMCBhdG9tLTEnIGQ9J00gMy40LDQ3LjUgTCAzNS4xLDI5LjInIHN0eWxlPSdmaWxsOm5vbmU7ZmlsbC1ydWxlOmV2ZW5vZGQ7c3Ryb2tlOiMzQjQxNDM7c3Ryb2tlLXdpZHRoOjEuMHB4O3N0cm9rZS1saW5lY2FwOmJ1dHQ7c3Ryb2tlLWxpbmVqb2luOm1pdGVyO3N0cm9rZS1vcGFjaXR5OjEnIC8+CjxwYXRoIGNsYXNzPSdib25kLTEgYXRvbS0xIGF0b20tMicgZD0nTSAzNS4xLDI5LjIgTCA0OC4zLDM2LjgnIHN0eWxlPSdmaWxsOm5vbmU7ZmlsbC1ydWxlOmV2ZW5vZGQ7c3Ryb2tlOiMzQjQxNDM7c3Ryb2tlLXdpZHRoOjEuMHB4O3N0cm9rZS1saW5lY2FwOmJ1dHQ7c3Ryb2tlLWxpbmVqb2luOm1pdGVyO3N0cm9rZS1vcGFjaXR5OjEnIC8+CjxwYXRoIGNsYXNzPSdib25kLTEgYXRvbS0xIGF0b20tMicgZD0nTSA0OC4zLDM2LjggTCA2MS41LDQ0LjQnIHN0eWxlPSdmaWxsOm5vbmU7ZmlsbC1ydWxlOmV2ZW5vZGQ7c3Ryb2tlOiNFODQyMzU7c3Ryb2tlLXdpZHRoOjEuMHB4O3N0cm9rZS1saW5lY2FwOmJ1dHQ7c3Ryb2tlLWxpbmVqb2luOm1pdGVyO3N0cm9rZS1vcGFjaXR5OjEnIC8+Cjx0ZXh0IHg9JzYyLjQnIHk9JzU0LjgnIGNsYXNzPSdhdG9tLTInIHN0eWxlPSdmb250LXNpemU6MTRweDtmb250LXN0eWxlOm5vcm1hbDtmb250LXdlaWdodDpub3JtYWw7ZmlsbC1vcGFjaXR5OjE7c3Ryb2tlOm5vbmU7Zm9udC1mYW1pbHk6c2Fucy1zZXJpZjt0ZXh0LWFuY2hvcjpzdGFydDtmaWxsOiNFODQyMzUnID5PPC90ZXh0Pgo8dGV4dCB4PSc3Mi41JyB5PSc1NC44JyBjbGFzcz0nYXRvbS0yJyBzdHlsZT0nZm9udC1zaXplOjE0cHg7Zm9udC1zdHlsZTpub3JtYWw7Zm9udC13ZWlnaHQ6bm9ybWFsO2ZpbGwtb3BhY2l0eToxO3N0cm9rZTpub25lO2ZvbnQtZmFtaWx5OnNhbnMtc2VyaWY7dGV4dC1hbmNob3I6c3RhcnQ7ZmlsbDojRTg0MjM1JyA+SDwvdGV4dD4KPC9zdmc+Cg== CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 74
- 230000000694 effects Effects 0.000 claims description 67
- 238000010992 reflux Methods 0.000 claims description 50
- 238000000605 extraction Methods 0.000 claims description 41
- 238000001035 drying Methods 0.000 claims description 27
- 210000000952 Spleen Anatomy 0.000 claims description 23
- 238000010438 heat treatment Methods 0.000 claims description 17
- 241000209149 Zea Species 0.000 claims description 16
- 239000000203 mixture Substances 0.000 claims description 16
- 210000002784 Stomach Anatomy 0.000 claims description 15
- 239000003814 drug Substances 0.000 claims description 14
- 210000003097 Mucus Anatomy 0.000 claims description 11
- 238000005728 strengthening Methods 0.000 claims description 10
- 238000009472 formulation Methods 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 7
- 206010036790 Productive cough Diseases 0.000 claims description 6
- 230000000968 intestinal Effects 0.000 claims description 6
- 239000008187 granular material Substances 0.000 claims description 5
- 239000004570 mortar (masonry) Substances 0.000 claims description 5
- 238000005292 vacuum distillation Methods 0.000 claims description 5
- 241000282994 Cervidae Species 0.000 claims description 3
- 229940023488 Pill Drugs 0.000 claims description 3
- 239000006187 pill Substances 0.000 claims description 3
- 230000001476 alcoholic Effects 0.000 claims 1
- 239000003292 glue Substances 0.000 claims 1
- 210000004369 Blood Anatomy 0.000 abstract description 36
- 239000008280 blood Substances 0.000 abstract description 36
- 230000036541 health Effects 0.000 abstract description 8
- 210000000056 organs Anatomy 0.000 abstract description 8
- 230000033228 biological regulation Effects 0.000 abstract description 5
- 231100000486 side effect Toxicity 0.000 abstract description 5
- 240000008042 Zea mays Species 0.000 abstract description 3
- 230000002708 enhancing Effects 0.000 abstract description 2
- 239000000047 product Substances 0.000 description 80
- 108020003112 toxins Proteins 0.000 description 23
- 210000004185 Liver Anatomy 0.000 description 21
- 230000000670 limiting Effects 0.000 description 20
- 201000010099 disease Diseases 0.000 description 16
- 230000000052 comparative effect Effects 0.000 description 15
- 235000009508 confectionery Nutrition 0.000 description 13
- 210000004072 Lung Anatomy 0.000 description 12
- 241000736199 Paeonia Species 0.000 description 12
- 231100000614 Poison Toxicity 0.000 description 12
- 239000002574 poison Substances 0.000 description 12
- 210000000936 Intestines Anatomy 0.000 description 10
- 210000003734 Kidney Anatomy 0.000 description 10
- 208000002193 Pain Diseases 0.000 description 10
- 230000036407 pain Effects 0.000 description 10
- 206010011224 Cough Diseases 0.000 description 7
- 238000004140 cleaning Methods 0.000 description 7
- 231100000224 toxic side effect Toxicity 0.000 description 7
- HVYWMOMLDIMFJA-DPAQBDIFSA-N (3β)-Cholest-5-en-3-ol Chemical compound data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 201.4,191.8 L 224.7,181.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-11 atom-0' d='M 180.7,176.8 L 201.4,191.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 224.7,181.4 L 227.4,156.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 220.0,177.1 L 221.9,159.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 227.4,156.0 L 250.7,145.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-29 atom-8 atom-2' d='M 206.7,141.0 L 227.4,156.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 250.7,145.6 L 253.4,120.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 258.7,118.8 L 258.0,117.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 264.0,117.3 L 262.6,114.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 269.4,115.9 L 267.3,111.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-4 atom-6' d='M 253.4,120.2 L 232.7,105.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 232.7,105.2 L 209.4,115.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 209.4,115.6 L 206.7,141.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 202.9,137.6 L 202.3,138.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 199.1,134.2 L 197.9,135.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 195.2,130.7 L 193.4,133.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 191.4,127.3 L 189.0,130.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 187.6,123.9 L 184.6,128.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 206.7,141.0 L 183.4,151.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 183.4,151.4 L 180.7,176.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-30 atom-27 atom-10' d='M 162.7,136.4 L 183.4,151.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-10 atom-28' d='M 183.4,151.4 L 194.7,162.8 L 197.7,158.6 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-11 atom-11 atom-12' d='M 180.7,176.8 L 157.4,187.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-32 atom-11 atom-29' d='M 179.3,182.2 L 181.0,182.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-32 atom-11 atom-29' d='M 177.9,187.7 L 181.2,188.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-32 atom-11 atom-29' d='M 176.4,193.1 L 181.5,193.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 157.4,187.2 L 149.5,211.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-24 atom-12' d='M 136.7,172.1 L 157.4,187.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-33 atom-12 atom-30' d='M 157.4,187.2 L 140.5,186.4 L 141.0,191.4 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-13 atom-13 atom-14' d='M 149.5,211.4 L 124.0,211.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-15 atom-14' d='M 117.2,192.2 L 118.1,191.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-15 atom-14' d='M 118.3,197.2 L 120.2,196.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-15 atom-14' d='M 119.4,202.2 L 122.3,201.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-15 atom-14' d='M 120.4,207.2 L 124.3,206.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-15 atom-14' d='M 121.5,212.2 L 126.4,210.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 116.1,187.2 L 91.8,179.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-15 atom-24' d='M 116.1,187.2 L 136.7,172.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 87.7,182.3 L 88.3,183.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 83.5,185.3 L 84.9,186.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 79.4,188.4 L 81.4,190.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 75.2,191.4 L 78.0,194.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 71.1,194.5 L 74.5,198.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-16 atom-18' d='M 91.8,179.3 L 86.5,154.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 86.5,154.3 L 62.2,146.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 62.2,146.4 L 56.9,121.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 56.9,121.4 L 32.6,113.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 32.6,113.5 L 27.3,88.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 32.6,113.5 L 13.6,130.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 132.6,169.2 L 132.1,170.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 128.4,166.2 L 127.4,167.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 124.2,163.2 L 122.7,165.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 120.1,160.2 L 118.0,163.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 115.9,157.2 L 113.3,161.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-24 atom-26' d='M 136.7,172.1 L 139.4,146.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-26 atom-27' d='M 139.4,146.8 L 162.7,136.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='273.6' y='114.9' class='atom-5' style='font-size:10px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='280.7' y='114.9' class='atom-5' style='font-size:10px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='201.0' y='171.5' class='atom-28' style='font-size:10px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
<text x='175.0' y='207.3' class='atom-29' style='font-size:10px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
<text x='128.9' y='194.9' class='atom-30' style='font-size:10px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 54.8,53.4 L 61.2,50.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-27 atom-11 atom-0' d='M 49.2,49.3 L 54.8,53.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 61.2,50.5 L 62.0,43.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 60.0,49.3 L 60.5,44.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 62.0,43.6 L 68.4,40.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-29 atom-8 atom-2' d='M 56.3,39.4 L 62.0,43.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-3 atom-4' d='M 68.4,40.7 L 69.1,33.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 70.7,33.3 L 70.5,32.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 72.2,32.9 L 71.9,32.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 73.8,32.4 L 73.2,31.1' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-4 atom-6' d='M 69.1,33.7 L 63.4,29.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 63.4,29.6 L 57.0,32.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 57.0,32.5 L 56.3,39.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 54.6,37.9 L 54.3,38.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 52.8,36.3 L 52.3,37.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 51.1,34.8 L 50.2,35.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-8 atom-10' d='M 56.3,39.4 L 49.9,42.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 49.9,42.3 L 49.2,49.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-30 atom-27 atom-10' d='M 44.2,38.2 L 49.9,42.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-31 atom-10 atom-28' d='M 49.9,42.3 L 53.2,45.5 L 54.0,44.4 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-11 atom-11 atom-12' d='M 49.2,49.3 L 42.8,52.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-32 atom-11 atom-29' d='M 48.8,50.9 L 49.2,50.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-32 atom-11 atom-29' d='M 48.4,52.5 L 49.3,52.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-32 atom-11 atom-29' d='M 48.0,54.2 L 49.3,54.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-12 atom-13' d='M 42.8,52.1 L 40.6,58.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-28 atom-24 atom-12' d='M 37.1,48.0 L 42.8,52.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-33 atom-12 atom-30' d='M 42.8,52.1 L 37.7,51.9 L 37.9,53.3 Z' style='fill:#3B4143;fill-rule:evenodd;fill-opacity:1;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1;' />
<path class='bond-13 atom-13 atom-14' d='M 40.6,58.8 L 33.6,58.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-15 atom-14' d='M 32.0,54.4 L 32.4,54.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-15 atom-14' d='M 32.5,56.7 L 33.3,56.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-15 atom-14' d='M 33.0,59.0 L 34.3,58.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 31.5,52.1 L 24.8,49.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-15 atom-24' d='M 31.5,52.1 L 37.1,48.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 22.9,51.3 L 23.2,51.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 21.0,52.7 L 21.6,53.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 19.1,54.1 L 20.1,55.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-16 atom-18' d='M 24.8,49.9 L 23.3,43.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 23.3,43.1 L 16.7,40.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 16.7,40.9 L 15.2,34.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 15.2,34.1 L 8.6,31.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 8.6,31.9 L 7.1,25.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 8.6,31.9 L 3.4,36.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 35.2,46.6 L 35.0,47.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 33.3,45.2 L 32.8,46.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-24 atom-25' d='M 31.4,43.9 L 30.7,45.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-24 atom-26' d='M 37.1,48.0 L 37.8,41.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-26 atom-27' d='M 37.8,41.0 L 44.2,38.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='73.7' y='33.9' class='atom-5' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='77.8' y='33.9' class='atom-5' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='53.8' y='49.4' class='atom-28' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
<text x='46.6' y='59.2' class='atom-29' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
<text x='34.0' y='55.8' class='atom-30' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#3B4143' >H</text>
</svg>
 C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 6
- 210000002216 Heart Anatomy 0.000 description 6
- 239000007789 gas Substances 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 230000001737 promoting Effects 0.000 description 6
- 206010010774 Constipation Diseases 0.000 description 5
- 208000002173 Dizziness Diseases 0.000 description 5
- 208000010228 Erectile Dysfunction Diseases 0.000 description 5
- 206010022114 Injury Diseases 0.000 description 5
- 206010030113 Oedema Diseases 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 210000000038 chest Anatomy 0.000 description 5
- 235000018927 edible plant Nutrition 0.000 description 5
- 201000001881 impotence Diseases 0.000 description 5
- 235000016709 nutrition Nutrition 0.000 description 5
- 210000001015 Abdomen Anatomy 0.000 description 4
- 206010000060 Abdominal distension Diseases 0.000 description 4
- 208000006673 Asthma Diseases 0.000 description 4
- 241000668709 Dipterocarpus costatus Species 0.000 description 4
- 210000000232 Gallbladder Anatomy 0.000 description 4
- 240000004371 Panax ginseng Species 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 4
- 240000002381 Prunus davidiana Species 0.000 description 4
- 235000015533 Prunus davidiana Nutrition 0.000 description 4
- 238000009835 boiling Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 230000013872 defecation Effects 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- 150000002632 lipids Chemical class 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 230000002829 reduced Effects 0.000 description 4
- 230000002522 swelling Effects 0.000 description 4
- 230000001225 therapeutic Effects 0.000 description 4
- 206010067484 Adverse reaction Diseases 0.000 description 3
- 229940107161 Cholesterol Drugs 0.000 description 3
- 206010012601 Diabetes mellitus Diseases 0.000 description 3
- 206010019233 Headache Diseases 0.000 description 3
- 210000001624 Hip Anatomy 0.000 description 3
- 208000008454 Hyperhidrosis Diseases 0.000 description 3
- 208000008425 Protein Deficiency Diseases 0.000 description 3
- 206010072736 Rheumatic disease Diseases 0.000 description 3
- 230000003187 abdominal Effects 0.000 description 3
- 231100000494 adverse effect Toxicity 0.000 description 3
- 230000004087 circulation Effects 0.000 description 3
- 238000010835 comparative analysis Methods 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 229940079593 drugs Drugs 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 231100000869 headache Toxicity 0.000 description 3
- 210000004914 menses Anatomy 0.000 description 3
- 230000005906 menstruation Effects 0.000 description 3
- 230000025627 positive regulation of urine volume Effects 0.000 description 3
- 230000002035 prolonged Effects 0.000 description 3
- 230000002633 protecting Effects 0.000 description 3
- 238000010926 purge Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000035900 sweating Effects 0.000 description 3
- 206010000077 Abdominal mass Diseases 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- 206010000496 Acne Diseases 0.000 description 2
- 206010001928 Amenorrhoea Diseases 0.000 description 2
- 206010003549 Asthenia Diseases 0.000 description 2
- 210000000988 Bone and Bones Anatomy 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 208000001848 Dysentery Diseases 0.000 description 2
- 206010018836 Haematochezia Diseases 0.000 description 2
- 206010018987 Haemorrhage Diseases 0.000 description 2
- 208000006750 Hematuria Diseases 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 206010023126 Jaundice Diseases 0.000 description 2
- 210000003127 Knee Anatomy 0.000 description 2
- 210000003205 Muscles Anatomy 0.000 description 2
- 206010036067 Polydipsia Diseases 0.000 description 2
- 240000005809 Prunus persica Species 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 238000000944 Soxhlet extraction Methods 0.000 description 2
- 210000004304 Subcutaneous Tissue Anatomy 0.000 description 2
- 210000003932 Urinary Bladder Anatomy 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 230000000202 analgesic Effects 0.000 description 2
- 230000003712 anti-aging Effects 0.000 description 2
- 230000001147 anti-toxic Effects 0.000 description 2
- 230000000259 anti-tumor Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 231100000319 bleeding Toxicity 0.000 description 2
- 230000000740 bleeding Effects 0.000 description 2
- 230000036770 blood supply Effects 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 201000001352 cholecystitis Diseases 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000001976 improved Effects 0.000 description 2
- 230000001965 increased Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000000414 obstructive Effects 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000001105 regulatory Effects 0.000 description 2
- 230000001624 sedative Effects 0.000 description 2
- 239000000932 sedative agent Substances 0.000 description 2
- 210000000697 sensory organs Anatomy 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 201000010874 syndrome Diseases 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 230000002936 tranquilizing Effects 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 241001465677 Ancylostomatoidea Species 0.000 description 1
- 235000007639 Anthemis cotula Nutrition 0.000 description 1
- 210000001367 Arteries Anatomy 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 206010003445 Ascites Diseases 0.000 description 1
- 210000003445 Biliary Tract Anatomy 0.000 description 1
- 210000004204 Blood Vessels Anatomy 0.000 description 1
- 210000001124 Body Fluids Anatomy 0.000 description 1
- 210000004556 Brain Anatomy 0.000 description 1
- 240000000218 Cannabis sativa Species 0.000 description 1
- 240000008574 Capsicum frutescens Species 0.000 description 1
- 240000004528 Catalpa ovata Species 0.000 description 1
- 235000010005 Catalpa ovata Nutrition 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 241000522215 Dipteryx odorata Species 0.000 description 1
- 208000000718 Duodenal Ulcer Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 101700032127 ETX1 Proteins 0.000 description 1
- 101700029730 ETX2 Proteins 0.000 description 1
- 231100000655 Enterotoxin Toxicity 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 240000003218 Eryngium foetidum Species 0.000 description 1
- 235000010283 Eryngium foetidum Nutrition 0.000 description 1
- 241000208688 Eucommia Species 0.000 description 1
- 230000036826 Excretion Effects 0.000 description 1
- 210000003414 Extremities Anatomy 0.000 description 1
- 206010016029 Face oedema Diseases 0.000 description 1
- 210000003608 Feces Anatomy 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 210000001035 Gastrointestinal Tract Anatomy 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 206010062060 Hyperlipidaemia Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010022437 Insomnia Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 208000000913 Kidney Calculi Diseases 0.000 description 1
- 210000002414 Leg Anatomy 0.000 description 1
- 240000001313 Lycium barbarum Species 0.000 description 1
- 235000015459 Lycium barbarum Nutrition 0.000 description 1
- 208000008466 Metabolic Disease Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 208000003067 Myocardial Ischemia Diseases 0.000 description 1
- 206010029148 Nephrolithiasis Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 210000003516 Pericardium Anatomy 0.000 description 1
- 206010037009 Protein metabolism disorder Diseases 0.000 description 1
- 206010037844 Rash Diseases 0.000 description 1
- 240000001341 Reynoutria japonica Species 0.000 description 1
- 235000018167 Reynoutria japonica Nutrition 0.000 description 1
- 210000000582 Semen Anatomy 0.000 description 1
- 210000002966 Serum Anatomy 0.000 description 1
- 210000003491 Skin Anatomy 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 206010042170 Strangury Diseases 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 235000003595 Tagetes minuta Nutrition 0.000 description 1
- 210000002435 Tendons Anatomy 0.000 description 1
- 235000008214 Thlaspi arvense Nutrition 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 206010068760 Ulcers Diseases 0.000 description 1
- 206010046788 Uterine haemorrhage Diseases 0.000 description 1
- 210000004291 Uterus Anatomy 0.000 description 1
- 210000003462 Veins Anatomy 0.000 description 1
- 240000004922 Vigna radiata Species 0.000 description 1
- 235000010721 Vigna radiata var radiata Nutrition 0.000 description 1
- 235000011469 Vigna radiata var sublobata Nutrition 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000003213 activating Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 201000000736 amenorrhea Diseases 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 230000001396 anti-anti-diuretic Effects 0.000 description 1
- 230000003276 anti-hypertensive Effects 0.000 description 1
- 230000003110 anti-inflammatory Effects 0.000 description 1
- 230000002019 anti-mutation Effects 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 201000009361 ascariasis Diseases 0.000 description 1
- 244000052616 bacterial pathogens Species 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 101710023118 btfP Proteins 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 230000002279 cholagogic Effects 0.000 description 1
- 230000001684 chronic Effects 0.000 description 1
- 230000000295 complement Effects 0.000 description 1
- 231100000895 deafness Toxicity 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 201000008286 diarrhea Diseases 0.000 description 1
- 230000001882 diuretic Effects 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 239000000147 enterotoxin Substances 0.000 description 1
- 230000029578 entry into host Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 201000005577 familial hyperlipidemia Diseases 0.000 description 1
- 230000001605 fetal Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 230000011132 hemopoiesis Effects 0.000 description 1
- 230000002218 hypoglycaemic Effects 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000002440 industrial waste Substances 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 238000011031 large scale production Methods 0.000 description 1
- 201000010260 leiomyoma Diseases 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 235000015091 medicinal tea Nutrition 0.000 description 1
- 230000002175 menstrual Effects 0.000 description 1
- 230000002503 metabolic Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 230000000116 mitigating Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000006011 modification reaction Methods 0.000 description 1
- 230000002107 myocardial Effects 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 235000021251 pulses Nutrition 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000003014 reinforcing Effects 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000000630 rising Effects 0.000 description 1
- 239000000917 skin toxin Substances 0.000 description 1
- 230000002269 spontaneous Effects 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 201000004595 synovitis Diseases 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 230000002588 toxic Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000000472 traumatic Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances data:image/svg+xml;base64,PD94bWwgdmVyc2lvbj0nMS4wJyBlbmNvZGluZz0naXNvLTg4NTktMSc/Pgo8c3ZnIHZlcnNpb249JzEuMScgYmFzZVByb2ZpbGU9J2Z1bGwnCiAgICAgICAgICAgICAgeG1sbnM9J2h0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnJwogICAgICAgICAgICAgICAgICAgICAgeG1sbnM6cmRraXQ9J2h0dHA6Ly93d3cucmRraXQub3JnL3htbCcKICAgICAgICAgICAgICAgICAgICAgIHhtbG5zOnhsaW5rPSdodHRwOi8vd3d3LnczLm9yZy8xOTk5L3hsaW5rJwogICAgICAgICAgICAgICAgICB4bWw6c3BhY2U9J3ByZXNlcnZlJwp3aWR0aD0nMzAwcHgnIGhlaWdodD0nMzAwcHgnIHZpZXdCb3g9JzAgMCAzMDAgMzAwJz4KPCEtLSBFTkQgT0YgSEVBREVSIC0tPgo8cmVjdCBzdHlsZT0nb3BhY2l0eToxLjA7ZmlsbDojRkZGRkZGO3N0cm9rZTpub25lJyB3aWR0aD0nMzAwLjAnIGhlaWdodD0nMzAwLjAnIHg9JzAuMCcgeT0nMC4wJz4gPC9yZWN0Pgo8dGV4dCB4PScxMDAuNScgeT0nMTcwLjAnIGNsYXNzPSdhdG9tLTAnIHN0eWxlPSdmb250LXNpemU6NDBweDtmb250LXN0eWxlOm5vcm1hbDtmb250LXdlaWdodDpub3JtYWw7ZmlsbC1vcGFjaXR5OjE7c3Ryb2tlOm5vbmU7Zm9udC1mYW1pbHk6c2Fucy1zZXJpZjt0ZXh0LWFuY2hvcjpzdGFydDtmaWxsOiNFODQyMzUnID5IPC90ZXh0Pgo8dGV4dCB4PScxMjYuMScgeT0nMTg2LjAnIGNsYXNzPSdhdG9tLTAnIHN0eWxlPSdmb250LXNpemU6MjZweDtmb250LXN0eWxlOm5vcm1hbDtmb250LXdlaWdodDpub3JtYWw7ZmlsbC1vcGFjaXR5OjE7c3Ryb2tlOm5vbmU7Zm9udC1mYW1pbHk6c2Fucy1zZXJpZjt0ZXh0LWFuY2hvcjpzdGFydDtmaWxsOiNFODQyMzUnID4yPC90ZXh0Pgo8dGV4dCB4PScxMzguMCcgeT0nMTcwLjAnIGNsYXNzPSdhdG9tLTAnIHN0eWxlPSdmb250LXNpemU6NDBweDtmb250LXN0eWxlOm5vcm1hbDtmb250LXdlaWdodDpub3JtYWw7ZmlsbC1vcGFjaXR5OjE7c3Ryb2tlOm5vbmU7Zm9udC1mYW1pbHk6c2Fucy1zZXJpZjt0ZXh0LWFuY2hvcjpzdGFydDtmaWxsOiNFODQyMzUnID5PPC90ZXh0Pgo8L3N2Zz4K data:image/svg+xml;base64,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 O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Abstract
The present invention relates to medical health product technical field, is related to a kind of detoxifying health-care product and its preparation method and application.The detoxifying health-care product of the present invention, including radix glycyrrhizae, ginkgo leaf, rhizoma alismatis, oriental wormwood, turmeric, lotus leaf, the fruit of Chinese wolfberry, peach kernel, dark plum, spina date seed, ginseng, pilose antler, hippocampus, ganoderma lucidum, Ligusticum wallichii, the bighead atractylodes rhizome, sealwort, radix bupleuri, the root of herbaceous peony, rascal, Radix Angelicae Sinensis, corn stigma, root tuber of aromatic turmeric and Herba Lycopi.The detoxifying health-care product of the present invention, unnecessary side effect will not be brought to body, safe to use, convenient and quick, for excluding the toxin in vivo in the dirty insidious and blood of each internal organs, regulation recovers total balance of the body, enhancing body resistivity has positive role.
Description
Technical field
The present invention relates to medical health product technical field, more particularly to a kind of detoxifying health-care product and preparation method thereof and should
With.
Background technology
With the quickening of modernization step, under the overall situation of pollution getting worse, the invasion of " modern civilization diseases " and wound
Evil, increasingly affects the work and life of people;The toxin accumulated in people's body accordingly increases, and is born to caused by human body
It is increasing.
Human toxin, it is rubbish unnecessary in vivo in fact, mainly includes two major classes:" external poison " and " interior raw poison ".
" external poison " mainly includes what atmosphere pollution, vehicle exhaust, industrial waste gas, chemicals, junk food etc. were brought to human body
The deposition in human body such as toxic side effect and pathogenic microorganism;" interior raw poison " mainly includes producing in normal metabolic processes
Metabolic waste, delay of the poison in human body caused by enteral stool and glycolipid fat protein metabolism disorder.Only by this
A little toxin are discharged in time, can just be kept fit.Various toxin, waste retain can cause metabolic disorder in vivo, hinder gas
Blood normal operation, destroy internal organs function and internal organs it is dirty between it is mutually coordinated.In addition, a large amount of accumulation of vivotoxin can also trigger
The diseases such as fever, tumour, seriously endanger human health.
Various toxin expelling methods or toxins eliminating agent be also there is some drawbacks in the market, as some curative effects are also possible that but secondary
Effect is big, may cause new hidden danger, can also produce dependence;Some DeGrains, curative effect are not notable enough;Some prices are held high
Expensive, large-scale production is restricted.So as to, research and develop a kind of drug action it is good, without adverse reaction and cost it is cheap
Detoxifying health-care product, have important practical significance.
In view of this, it is special to propose the present invention.
The content of the invention
The first object of the present invention is to provide a kind of detoxifying health-care product, using medicinal and edible plant as primary raw material, there is pin
To the reasonable compatibility of property, the toxin in body can be effectively excluded, and have no toxic side effect.
The second object of the present invention is to provide a kind of preparation method of detoxifying health-care product, and this method flow is simple, operation
Conveniently, the effect of can giving full play to each raw material, the active ingredient of raw material has obtained more preferable enrichment, and product stability is good.
The third object of the present invention is that providing a kind of detoxifying health-care product is preparing with dispel stool, expelling intestinal toxin, strengthening the spleen and stomach
And/or the application in the medicine of clearing lung-heat expectoration effect, body immunity can be effectively improved, prevents the generation of various diseases.
In order to realize the above-mentioned purpose of the present invention, spy uses following technical scheme:
According to an aspect of the present invention, the present invention provides a kind of detoxifying health-care product, mainly by the raw material of following parts by weight
It is made:
40~80 parts of radix glycyrrhizae, 40~80 parts of ginkgo leaf, 5~15 parts of rhizoma alismatis, 5~12 parts of oriental wormwood, 6~16 parts of turmeric, lotus leaf
40~80 parts, 12~24 parts of the fruit of Chinese wolfberry, 10~18 parts of peach kernel, 15~30 parts of dark plum, 15~30 parts of spina date seed, ginseng 10~25
Part, 5~15 parts of pilose antler, 5~15 parts of hippocampus, 10~18 parts of ganoderma lucidum, 5~15 parts of Ligusticum wallichii, 5~15 parts of the bighead atractylodes rhizome, 2~12 parts of sealwort,
2~12 parts of radix bupleuri, 2~12 parts of the root of herbaceous peony, 2~12 parts of rascal, 2~12 parts of Radix Angelicae Sinensis, 5~15 parts of corn stigma, 5~15 parts of root tuber of aromatic turmeric and pool
It is blue 5~15 parts.
As further preferred technical scheme, the detoxifying health-care product are mainly made up of the raw material of following parts by weight:
50~70 parts of radix glycyrrhizae, 50~70 parts of ginkgo leaf, 8~10 parts of rhizoma alismatis, 7~9 parts of oriental wormwood, 10~12 parts of turmeric, lotus leaf
50~70 parts, 18~20 parts of the fruit of Chinese wolfberry, 13~15 parts of peach kernel, 20~25 parts of dark plum, 20~25 parts of spina date seed, ginseng 15~20
Part, 8~10 parts of pilose antler, 8~10 parts of hippocampus, 12~15 parts of ganoderma lucidum, 8~10 parts of Ligusticum wallichii, 8~10 parts of the bighead atractylodes rhizome, 5~8 parts of sealwort, bavin
5~8 parts recklessly, 5~8 parts of the root of herbaceous peony, 5~8 parts of rascal, 5~8 parts of Radix Angelicae Sinensis, 8~10 parts of corn stigma, 8~10 parts of root tuber of aromatic turmeric and Herba Lycopi 8~
10 parts.
As further preferred technical scheme, the detoxifying health-care product are mainly made up of the raw material of following parts by weight:
55~65 parts of radix glycyrrhizae, 55~65 parts of ginkgo leaf, 8.5~9.5 parts of rhizoma alismatis, 7.5~8.5 parts of oriental wormwood, turmeric 10.5~
11.5 parts, 55~65 parts of lotus leaf, 18.5~19.5 parts of the fruit of Chinese wolfberry, 13.5~14.5 parts of peach kernel, 21~23 parts of dark plum, spina date seed 21
~23 parts, 16~18 parts of ginseng, 8.5~9.5 parts of pilose antler, 8.5~9.5 parts of hippocampus, 13~14 parts of ganoderma lucidum, Ligusticum wallichii 8.5~9.5
Part, 8.5~9.5 parts of the bighead atractylodes rhizome, 6~7 parts of sealwort, 6~7 parts of radix bupleuri, 6~7 parts of the root of herbaceous peony, 6~7 parts of rascal, 6~7 parts of Radix Angelicae Sinensis, corn
8.5~9.5 parts of 8.5~9.5 parts of palpus, 8.5~9.5 parts of root tuber of aromatic turmeric and Herba Lycopi.
As further preferred technical scheme, the formulation of the detoxifying health-care product is oral formulations.
As further preferred technical scheme, the formulations of the detoxifying health-care product is tablet, capsule, granule, pill,
Pulvis or oral liquid.
According to another aspect of the present invention, the present invention also provides the preparation side of the detoxifying health-care product described in more than one
Method, it the described method comprises the following steps:
Each raw material is crushed respectively, alcohol extracting and drying, obtain each extract;
Each extract is mixed according to formula rate, the detoxifying health-care product are made.
As further preferred technical scheme, in described pulverising step, raw material is dried at 90 DEG C~115 DEG C first
To constant weight, then crushed to obtain powdered raw material with mortar;
Preferably, the temperature of drying is 100 DEG C~105 DEG C;
Preferably, the granularity of crushing is the mesh of 60 mesh~80.
As further preferred technical scheme, in described alcohol extracting step, the raw material after crushing is weighed first, is placed on
In extraction element, then add volumetric concentration and be 75%~90% ethanol solution heating and refluxing extraction 1~3 time, backflow every time carries
The time taken is 1~3 hour, and reflux temperature is 85 DEG C~98 DEG C, and the quality of raw material and the volume ratio of ethanol solution are 1:10~
30;
Preferably, the extraction element is apparatus,Soxhlet's;
Preferably, the volumetric concentration of the ethanol solution is 80%~85%;
Preferably, the time of each refluxing extraction is 2~2.5 hours, and reflux temperature is 88 DEG C~90 DEG C, the quality of raw material
Volume ratio with ethanol solution is 1:20~22.
As further preferred technical scheme, in described drying steps, ethanol is reclaimed using vacuum distillation mode first,
Mucus is obtained, then mucus is dried, obtains extract;
Preferably, dry temperature is 85 DEG C~105 DEG C.
According to another aspect of the present invention, the detoxifying health-care product that the present invention is also provided described in more than one have in preparation
Dispel stool, expelling intestinal toxin, strengthening the spleen and stomach and/or clearing lung-heat expectoration effect medicine in application.
Compared with prior art, the beneficial effects of the present invention are:
1st, detoxifying health-care product provided by the invention, targetedly reasonable compatibility, with radix glycyrrhizae, ginkgo leaf, lotus leaf, the fruit of Chinese wolfberry
It is raw material Deng medicinal and edible plant, each raw material components are scientifically arranged in pairs or groups, and are influenced each other between each component, obtain synergy, battalion
Support it is with strong points, for people provide it is a kind of it is natural, safely and effectively, have no toxic side effect, the toxin expelling with significant toxin expelling curative effect
Health products.
Each medicinal and edible plant raw material of well-chosen of the present invention, each raw material cooperate, and not only toxin expelling curative effect is obvious, will not
Unnecessary side effect is brought to body, while there are three zones that are clear, adjusting, mend, that is, it is clear in arranging, adjust in clear, mended in tune;Clothes
Human body is enabled to reach through effect logical, that gas is logical, magic, blood is logical and just logical after;With broad spectrum activity, high efficiency, agility,
Safe without toxic side effect, content of beary metal zero, it is moderate the advantages of.
2nd, the preparation method of detoxifying health-care product provided by the invention, flow is simple, easy to operate, can give full play to each original
The effect of material, effective nutritional ingredient of each raw material have obtained more preferable enrichment, have reduced the invalid components in medicine, and nutrition is rich
Richness, mouthfeel is excellent, safe without toxic side effect, and product stability is good, and for excluding vivotoxin, regulation recovers total balance of the body, increases
Strong resistance has positive role, is easy to industrialized production.
3rd, detoxifying health-care product provided by the invention are applied and prepared with dispel stool, expelling intestinal toxin, strengthening the spleen and stomach and/or clearing lung-heat
In the medicine of expectoration effect, unnecessary side effect will not be brought to body, instant is again quick, for excluding each internal organs in vivo
Toxin in dirty insidious and blood, regulation recovers total balance of the body, enhancing body resistivity has positive role.
Embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment and embodiment, but this area skill
Art personnel will be understood that following embodiments and embodiment are merely to illustrate the present invention, and be not construed as the model of the limitation present invention
Enclose.Based on the embodiment in the present invention, what those of ordinary skill in the art were obtained under the premise of creative work is not made
Every other embodiment, belongs to the scope of protection of the invention.Unreceipted actual conditions person, builds according to normal condition or manufacturer
The condition of view is carried out.Agents useful for same or the unreceipted production firm person of instrument, it is the conventional production that can be obtained by commercially available purchase
Product.
In a first aspect, present embodiment provides a kind of detoxifying health-care product, mainly it is made up of the raw material of following parts by weight:
40~80 parts of radix glycyrrhizae, 40~80 parts of ginkgo leaf, 5~15 parts of rhizoma alismatis, 5~12 parts of oriental wormwood, 6~16 parts of turmeric, lotus leaf
40~80 parts, 12~24 parts of the fruit of Chinese wolfberry, 10~18 parts of peach kernel, 15~30 parts of dark plum, 15~30 parts of spina date seed, ginseng 10~25
Part, 5~15 parts of pilose antler, 5~15 parts of hippocampus, 10~18 parts of ganoderma lucidum, 5~15 parts of Ligusticum wallichii, 5~15 parts of the bighead atractylodes rhizome, 2~12 parts of sealwort,
2~12 parts of radix bupleuri, 2~12 parts of the root of herbaceous peony, 2~12 parts of rascal, 2~12 parts of Radix Angelicae Sinensis, 5~15 parts of corn stigma, 5~15 parts of root tuber of aromatic turmeric and pool
It is blue 5~15 parts.
In the present invention, the effect of each raw material and effect is as follows:
Radix glycyrrhizae:It is mild-natured, sweet, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, the work(of coordinating the drug actions of a prescription
Effect.Meanwhile radix glycyrrhizae energy emergency, moreover it is possible to play the mediation effect to all medicines, most of Traditional Chinese medicinal prescription has all been arranged in pairs or groups radix glycyrrhizae, so-called
" grass of ten side nine ", especially because its sweet taste can cover the toil taste of other medicinal materials, patient is set to be easier to receive.In the present invention,
Count in parts by weight, the typical but non-limiting content of radix glycyrrhizae is:40 parts, 45 parts, 50 parts, 55 parts, 60 parts, 65 parts, 70 parts, 75
Part or 80 parts.
Ginkgo leaf:It is sweet, bitter, puckery, it is mild-natured, have promoting blood circulation and removing blood stasis, remove obstruction in channels to relieve pain, astringe the lung and relieving asthma, the effect of changing turbid lipid-loweringing;
Cholesterol levels in blood of human body can also be reduced, artery sclerosis is prevented, also has improvement result to myocardial ischemia.In the present invention,
Count in parts by weight, the typical but non-limiting content of ginkgo leaf is:40 parts, 45 parts, 50 parts, 55 parts, 60 parts, 65 parts, 70 parts,
75 parts or 80 parts.
Rhizoma alismatis:It is sweet, it is light, it is cold in nature, return kidney, bladder warp;With clearing damp and promoting diuresis;Expel the heat-evil the effect for the treatment of stranguria.In addition, also help
In the transhipment and excretion of cholesterol, the absorption of cholesterol is disturbed, plays a part of reducing blood lipid;Its rhizoma alismatis element contained can reduce outer
Property hypercholesterolia in source enters in vivo, there is obvious effect for reducing fat, antihypertensive effect.In the present invention, count in parts by weight, rhizoma alismatis allusion quotation
Type but nonrestrictive content is:5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts or 15 parts.
Oriental wormwood:It is bitter, pungent, it is slightly cold, returns spleen, stomach, liver, gallbladder channel;Tonka-bean in oriental wormwood is known as Lipid-lowering activities, can lower serum courage
Sterol, mitigating aortosclerosis has liver function protecting, has the effect such as reducing blood lipid, decompression, coronary dilatation.In the present invention, by weight
Number meter is measured, the typical but non-limiting content of oriental wormwood is:5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts or 12 parts.
Turmeric:Acrid flavour, hardship, it is warm-natured;Returns spleen, Liver Channel;Blood-breaking, it is inducing meastruation to relieve menalgia;Twinged available for chest side of body, amenorrhoea, disease
Lump in the abdomen, rheumatism shoulder arm pain, tumbling and swelling;Also there is the effect such as reducing blood lipid, antitumor, anti-inflammatory.In the present invention, in parts by weight
Meter, the typical but non-limiting content of turmeric are:6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts, 15 parts or
16 parts.
Lotus leaf:Bitter, it is pungent micro-puckery, cool in nature cold;Cure mainly hot summer weather polydipsia, dizziness of having a headache, oedema, deficiency of food abdominal distension, rush down dysentery, in vain
Band, prolapse of the anus, spit blood, bleeding from five sense organs or subcutaneous tissue, spitting of blood, have blood in stool, uterine bleeding, post partum longtime lochia, traumatic blood stasis;Disinfected with toxin expelling, hypertension and hyperlipemia,
Raise the effect such as purging intense heat.In the present invention, count in parts by weight, the typical but non-limiting content of lotus leaf is:40 parts, 45 parts, 50
Part, 55 parts, 60 parts, 65 parts, 70 parts, 75 parts or 80 parts.
The fruit of Chinese wolfberry:It is mild-natured, it is sweet;Return liver and kidney channel;With nourishing liver and kidney, the effect of benefiting shrewd head;For consumption consumptive loss,
Soreness of waist and knee joint, dizziness and tinnitus, impotence and seminal emission, Heat Diabetes, blood deficiency chlorosis, blurred vision;There is facilitation to hematopoiesis function, also
There are anti-aging, anti-mutation, antitumor, anti-fatty liver and the effect such as hypoglycemic.In the present invention, count in parts by weight, fruit of Chinese wolfberry allusion quotation
Type but nonrestrictive content is:12 parts, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts,
23 parts or 24 parts.
Peach kernel:Bitter, it is mild-natured.Return hand, meridian of Foot-JUE YIN.The effect of with the silt of blood-breaking row, moisturize laxation;Stored for pyreticosis
Blood, traumatic injury, blood stasis and swelling pain.In the present invention, count in parts by weight, the typical but non-limiting content of peach kernel is:10 parts, 11
Part, 12 parts, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts or 18 parts.
Dark plum:It is sour, puckery, it is mild-natured;Return liver, spleen, lung, large intestine channel;For chronic cough of deficiency lung, abnormal heat polydipsia, chronic malaria, chronic diarrhea,
Dysentery, have blood in stool, hematuria;Metrorrhagia, ascariasis of biliary tract stomachache, vomiting, hookworm disease.Can protect stomach, eliminate constipation, improve a poor appetite, anti-aging,
Purify the blood and relieve the effect of alcohol, there is the effect of prevention disease and dispelling fatigue.In the present invention, count in parts by weight, dark plum is typical but unrestricted
The content of property is:15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts,
28 parts, 29 parts or 30 parts.
Spina date seed:It is sweet, it is mild-natured;Thoughts of returning home warp, the spleen channel, Liver Channel, gallbladder channel;With antitoxic heart-soothing and sedative, nourishing the liver, the effect of arrest sweating;
Available for antitoxic heart-soothing and sedative, nourishing the liver, arrest sweating.In the present invention, count in parts by weight, the typical but non-limiting content of spina date seed is:
15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts or
30 parts.
Ginseng:Slightly warm in nature, sweet, slight bitter;Returns spleen, lung, the heart, kidney channel;With reinforcing vital energy, veins takes off admittedly, reinforce the spleen to benefit the lung,
Promote the production of body fluid blood-nourishing, the effect of tranquilize the mind and promote the intelligence;To be taken off for physically weak, cold weak pulse of limb, spleen eating less, the deficiency syndrome of the lung is breathed with cough, injury thirst, interior heat
Quench one's thirst, deficiency of qi and blood, prolonged illness is empty to win, insomnia of palpitating with fear, impotence Gong Leng.In the present invention, count in parts by weight, ginseng is typical but non-limit
The content of property processed is:10 parts, 11 parts, 12 parts, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22
Part, 23 parts, 24 parts or 25 parts.
Pilose antler:It is sweet, salty, it is warm-natured;Return kidney, Liver Channel;With invigorating kidney yang, marrow is mended, strengthening the bones and muscles, adjusts punching to appoint, torr sore poison
Effect;Available for kidney deficiency, dizziness, deafness, mesh be dark, impotence, involuntary emission, uterus cold infertile, god are tired, chilly, spinal column crymodynia, muscles and bones impotence
Soft, cloudy subcutaneous ulcer is not held back and the diseases such as prolonged illness is deficient.It can increase defence capability of the body to the external world, adjust internal immunologic balance and keep away
Exempt from disease and occur and promote wound healing, sick body rehabilitation, so as to play a part of strengthening body, resistance aging.In the present invention, press
Parts by weight meter, the typical but non-limiting content of pilose antler are:5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13
Part, 14 parts or 15 parts.
Hippocampus:It is warm-natured, it is sweet;With tonifying kidney and strengthening yang, warm promoting blood circulation, tranquilizing and allaying excitement, mass dissipating and swelling eliminating, relaxing tendons and activating collaterals, cough-relieving
The effect of relievining asthma;Its is warm-natured supporing yang, energy warming meridian, has promoting blood circulation effect again, cures mainly kidney deficiency, impotence, the enuresis.In the present invention, press
Parts by weight meter, the typical but non-limiting content of hippocampus are:5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13
Part, 14 parts or 15 parts.
Ganoderma lucidum:It is warm-natured, it is lightly seasoned;With invigorating qi for tranquilization, it is relieving cough and asthma the effect of, for dizziness egersis, palpitation, consumptive disease
Cough and asthma;Its is sweet mild-natured, enters the heart channel of Hang-Shaoyin, can bushing blood, invigorating heart gas, tranquilizing mind, available for control insufficiency of vital energy and blood, the mind is lost caused by supporting
Have no peace of mind, have a sleepless night, palpitating with fear, dreaminess, the disease such as forgetful, the tired tired, deficiency of food of god of body;Also there is protecting liver and detoxication, improve cardiovascular system
Deng effect.In the present invention, count in parts by weight, the typical but non-limiting content of ganoderma lucidum is:5 parts, 6 parts, 7 parts, 8 parts, 9 parts,
10 parts, 11 parts, 12 parts, 13 parts, 14 parts, 15 parts 16 parts, 17 parts or 18 parts.
Ligusticum wallichii:Acrid flavour, it is warm-natured;Return liver, courage, pericardium channel;With blood-activating and qi-promoting, the effect of wind-expelling pain-stopping;Available for pacifying
Nerve, positive head wind headache, abdominal mass stomachache, chest side of body shouting pain, tumbling and swelling, headache, arthralgia pain due to rheumatism.In the present invention, in parts by weight
Meter, the typical but non-limiting content of Ligusticum wallichii are:5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts or
15 parts.
The bighead atractylodes rhizome:It is bitter, sweet, it is warm-natured;Returns spleen, stomach;With strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, it is antiabortive the effect of;Can
For diseases such as spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, fetal irritabilities.In the present invention, count in parts by weight,
The typical but non-limiting content of the bighead atractylodes rhizome is:5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts or 15
Part.
Sealwort:It is mild-natured, it is sweet;Returns spleen, lung, kidney channel;With boosting qi and nourishing yin, invigorating the spleen, moistening lung, the effect of kidney-nourishing;For spleen
Stomach Qi deficiency, fatigue and asthenia, deficiency of stomach-Yin, dry deficiency of food, deficiency syndrome of the lung cough caused by dryness, overstrain cough hemoptysis, asthenia of essence and blood, soreness and weakness of waist and knees, beard and hair are early
In vain, Heat Diabetes.In the present invention, count in parts by weight, the typical but non-limiting content of sealwort is:2 parts, 3 parts, 4 parts, 5 parts,
6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts or 12 parts.
Radix bupleuri:Bitter, pungent, cold nature;Return liver, courage, spleen, stomach, tri-jiao channel;Brought down a fever with evacuation, soothing liver-qi stagnation, rising Yang is lifted
Sunken function.In the present invention, count in parts by weight, the typical but non-limiting content of radix bupleuri is:2 parts, 3 parts, 4 parts, 5 parts, 6
Part, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts or 12 parts.
The root of herbaceous peony:Bitter, acid;Cold nature;Return liver, the spleen channel;With soft liver analgesic, nourishing blood for regulating menstruation, astringing YIN to stop sweating, suppressing liver-YANG
Function.In the present invention, count in parts by weight, the typical but non-limiting content of the root of herbaceous peony is:2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7
Part, 8 parts, 9 parts, 10 parts, 11 parts or 12 parts.
Rascal:It is bitter, pungent, it is warm-natured;Return liver, courage, stomach;With the function that soothing the liver relieving stagnant Qi, disperse accumulationsization are stagnant.In the present invention,
Count in parts by weight, the typical but non-limiting content of rascal is:2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts,
11 parts or 12 parts.
Radix Angelicae Sinensis:It is sweet, pungent;It is warm-natured, Return liver, the heart, the spleen channel;With enrich blood, invigorate blood circulation, menstruation regulating, analgesic, ease constipation function.This
In invention, count in parts by weight, the typical but non-limiting content of Radix Angelicae Sinensis is:2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9
Part, 10 parts, 11 parts or 12 parts.
Corn stigma:It is sweet, light, it is mild-natured;Return bladder, liver, gallbladder channel;Main oedema, dribbling urination, jaundice, cholecystitis, courage knot
Stone, hypertension, diabetes, alactation.Acted on reducing blood lipid, diuresis, decompression, cholagogic etc..In the present invention, in parts by weight
Meter, the typical but non-limiting content of corn stigma are:5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts
Or 15 parts.
Root tuber of aromatic turmeric:Acrid flavour, hardship, it is cool in nature;Enter the heart, lung, Liver Channel;With promoting qi circulation and removing obstruction in the collateral, the effect of cool blood broken stasis of blood, available for controlling chest
The all pains of abdomen side of body rib, the mistake heart is demented, pyreticosis coma, spits blood, bleeding from five sense organs or subcutaneous tissue, hematuria, blood strangury, women's vicarious menstruation, the disease such as jaundice.In the present invention,
Count in parts by weight, the typical but non-limiting content of root tuber of aromatic turmeric is:5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 part 13
Part, 14 parts or 15 parts.
Herba Lycopi:Bitter, pungent, slightly warm in nature;Return liver, the spleen channel;With promoting blood circulation, the effect of inducing diuresis for removing edema;Available for controlling blood
Stasis of blood Amenorrhea, stimulates the menstrual flow, abdominal mass, postpartum stasis of blood, body and face edema, injury from falling down, metal-inflicted wound, sore and toxic, oedema, the disease such as ascites.
In the present invention, count in parts by weight, the typical but non-limiting content of Herba Lycopi is:5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11
Part, 12 parts 13 parts, 14 parts or 15 parts.
The detoxifying health-care product that present embodiment provides, targetedly reasonable compatibility, with radix glycyrrhizae, ginkgo leaf, lotus leaf, matrimony vine
The medicinal and edible plants such as son are raw material, and each raw material components are scientifically arranged in pairs or groups, influenced each other between each component, obtain synergy,
For people provide it is a kind of it is natural, safely and effectively, the detoxifying health-care product that have no toxic side effect, there is significant toxin expelling curative effect.The row
Malicious health products will not bring unnecessary side effect to body, while have three zones that are clear, adjusting, mend, that is, clear in arranging, in clear
Adjust, mended in tune;Human body is enabled to reach through effect logical, that gas is logical, magic, blood is logical and just logical after taking;With broad spectrum activity, height
The advantages that effect property, agility.
In addition, when above-mentioned detoxifying health-care product raw material is using above-mentioned component composition and proportioning, described detoxifying health-care product
Influencing each other between middle various composition, complements each other, and synergy more preferably, can provide comprehensive nutritional support for patient,
The health value of above-mentioned medicinal and edible plant raw material can more be embodied.
Further, the detoxifying health-care product are mainly made up of the raw material of following parts by weight:
50~70 parts of radix glycyrrhizae, 50~70 parts of ginkgo leaf, 8~10 parts of rhizoma alismatis, 7~9 parts of oriental wormwood, 10~12 parts of turmeric, lotus leaf
50~70 parts, 18~20 parts of the fruit of Chinese wolfberry, 13~15 parts of peach kernel, 20~25 parts of dark plum, 20~25 parts of spina date seed, ginseng 15~20
Part, 8~10 parts of pilose antler, 8~10 parts of hippocampus, 12~15 parts of ganoderma lucidum, 8~10 parts of Ligusticum wallichii, 8~10 parts of the bighead atractylodes rhizome, 5~8 parts of sealwort, bavin
5~8 parts recklessly, 5~8 parts of the root of herbaceous peony, 5~8 parts of rascal, 5~8 parts of Radix Angelicae Sinensis, 8~10 parts of corn stigma, 8~10 parts of root tuber of aromatic turmeric and Herba Lycopi 8~
10 parts.
Further, the detoxifying health-care product are mainly made up of the raw material of following parts by weight:
55~65 parts of radix glycyrrhizae, 55~65 parts of ginkgo leaf, 8.5~9.5 parts of rhizoma alismatis, 7.5~8.5 parts of oriental wormwood, turmeric 10.5~
11.5 parts, 55~65 parts of lotus leaf, 18.5~19.5 parts of the fruit of Chinese wolfberry, 13.5~14.5 parts of peach kernel, 21~23 parts of dark plum, spina date seed 21
~23 parts, 16~18 parts of ginseng, 8.5~9.5 parts of pilose antler, 8.5~9.5 parts of hippocampus, 13~14 parts of ganoderma lucidum, Ligusticum wallichii 8.5~9.5
Part, 8.5~9.5 parts of the bighead atractylodes rhizome, 6~7 parts of sealwort, 6~7 parts of radix bupleuri, 6~7 parts of the root of herbaceous peony, 6~7 parts of rascal, 6~7 parts of Radix Angelicae Sinensis, corn
8.5~9.5 parts of 8.5~9.5 parts of palpus, 8.5~9.5 parts of root tuber of aromatic turmeric and Herba Lycopi.
By the proportioning between Reasonable adjustment each component, the coordinated effect between each component is given full play to, is improved
The health care curative effect of detoxifying health-care product, nutritious, mouthfeel is excellent, recovers total balance of the body, exclusion vivotoxin for regulation, reaches
Stable health status has significant effect.
In a kind of optional embodiment, the formulation of the detoxifying health-care product is oral formulations.
In a kind of optional embodiment, the formulations of the detoxifying health-care product is tablet, capsule, granule, pill,
Pulvis or oral liquid.
Preferably, the formulation of the detoxifying health-care product is oral liquid;Conveniently take, be easy to carry.
The detoxifying health-care product that present embodiment provides can be existing traditional oral pharmacy type, and preferably above-mentioned is several
Kind formulation, but this is not limited to, can also be medicinal tea or other formulations, use is easy to carry, and effect of ejecting poison is good, in daily middle company
The effect of continuous use can give full play to the cleaning of its toxin expelling, stimulate circulation.
Second aspect, present embodiment provide the preparation method of the detoxifying health-care product described in more than one, methods described bag
Include following steps:
Each raw material is crushed respectively, alcohol extracting and drying, obtain each extract;
Each extract is mixed according to formula rate, the detoxifying health-care product are made.
It is that all raw materials are uniformly put into boiling in extractor to obtain stoste mostly in existing preparation method,
This extraction mode of operation easily to contain chemical residual in a small number of raw materials, is also easy to so that patient vomiting occurs instead after taking
Stomach, skin is itched or the adverse reaction such as eruption, dizzy phenomenon.
And the preparation method for the detoxifying health-care product that present embodiment provides, all raw materials in formula are special using its physics
Property, by the way of single extraction, traditional extracting mode is changed, the chemical substance remained in medicine is reduced and human body is caused
Injury, the effect of more efficiently improving product.
It should be noted that after each extract is mixed according to formula rate, enter according to method commonly used in the prior art
Row preparation, so that granule, tablet or oral liquid etc. is made, you can obtain detoxifying health-care product.
Further speaking, the preparation method for the detoxifying health-care product that present embodiment provides, by the way that each raw material is carried out respectively
Crushing, alcohol extracting and drying, the mode for then again mixing obtained each extract so that effective nutritional ingredient of each raw material obtains
More preferable enrichment, reduces the invalid components in medicine, the effect of having given full play to each raw material, reduces residuals to human body
Caused by infringement, be not in adverse reaction.The detoxifying health-care product being prepared by the above method, stability is good, safe nothing
Toxic side effect, for excluding vivotoxin, regulation recovers total balance of the body, and resistance building has positive role, is easy to industrialize
Production.
In a kind of optional embodiment, in described pulverising step, raw material is dried at 90 DEG C~115 DEG C first
To constant weight, then crushed to obtain powdered raw material with mortar;
Preferably, the temperature of drying is 100 DEG C~105 DEG C;
Preferably, the granularity of crushing is the mesh of 60 mesh~80.
Alternatively, by before raw material stoving to constant weight, first raw material is cleaned, it is standby.
In a kind of specific embodiment, alternatively, the temperature of drying is 90 DEG C, 91 DEG C, 92 DEG C, 93 DEG C, 94 DEG C, 95
℃、96℃、97℃、98℃、98℃、99℃、100℃、101℃、102℃、103℃、104℃、105℃、106℃、107℃、
108 DEG C, 109 DEG C, 110 DEG C, 111 DEG C, 112 DEG C, 113 DEG C, 114 DEG C or 115 DEG C.The drying temperature of each raw material is slightly poor in formula
Not, such as the drying temperature of radix glycyrrhizae and ginkgo leaf is preferably 101 DEG C, and the drying temperature of rhizoma alismatis, oriental wormwood and turmeric is preferably 103
DEG C, the drying temperature of the fruit of Chinese wolfberry and peach kernel is preferably 99 DEG C, and the drying temperature of ginseng and pilose antler is preferably 97 DEG C etc..
In a kind of specific embodiment, alternatively, the granularity of powdered raw material is 60 mesh, 61 mesh, 62 mesh, 63
Mesh, 64 mesh, 65 mesh, 66 mesh, 67 mesh, 68 mesh, 69 mesh, 70 mesh, 71 mesh, 72 mesh, 73 mesh, 74 mesh, 75 mesh, 76 mesh, 77 mesh, 78
Mesh, 79 mesh or 80 mesh.The granularity that each raw material crushes in formula can also slightly have difference, but as long as within the above range.
In a kind of optional embodiment, in described alcohol extracting step, the raw material after crushing is weighed first, is placed on
In extraction element, then add volumetric concentration and be 75%~90% ethanol solution heating and refluxing extraction 1~3 time, backflow every time carries
The time taken is 1~3 hour, and reflux temperature is 85 DEG C~98 DEG C, and the quality of raw material and the volume ratio of ethanol solution are 1:10~
30;
Preferably, the extraction element is apparatus,Soxhlet's;
Preferably, the volumetric concentration of the ethanol solution is 80%~85%;
Preferably, the time of each refluxing extraction is 2~2.5 hours, and reflux temperature is 88 DEG C~90 DEG C, the quality of raw material
Volume ratio with ethanol solution is 1:20~22.
In a kind of specific embodiment, alternatively, the volumetric concentration of ethanol solution is 75%, 76%, 77%,
78%th, 79%, 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89% or 90%;Preferably 85%.
In a kind of specific embodiment, alternatively, the number of heating and refluxing extraction is 1 time, 2 times or 3 times.Using more
It during secondary heating and refluxing extraction, parallel can carry out, i.e., the operating parameter all same extracted every time, each secondary extract solution merged after extraction.
In a kind of specific embodiment, alternatively, time of each refluxing extraction is 1 hour, 1.5 hours, it is 2 small
When, 2.5 hours or 3 hours.
In a kind of specific embodiment, alternatively, reflux temperature be 85 DEG C, 86 DEG C, 87 DEG C, 88 DEG C, 89 DEG C, 90
DEG C, 91 DEG C, 92 DEG C, 93 DEG C, 94 DEG C, 95 DEG C, 96 DEG C, 97 DEG C or 98 DEG C.The reflux temperature of each raw material slightly has difference, example in formula
Reflux temperature such as radix glycyrrhizae and ginkgo leaf is preferably 90 DEG C, and the reflux temperature of rhizoma alismatis, oriental wormwood and turmeric is preferably 93 DEG C, the fruit of Chinese wolfberry
Reflux temperature with peach kernel is preferably 88 DEG C etc..
In a kind of specific embodiment, alternatively, the quality of raw material and volume ratio (the i.e. solid-liquid ratio g/ of ethanol solution
ML it is) 1:10、1:12、1:15、1:18、1:20、1:22、1:25、1:28 or 1:30.
In a kind of optional embodiment, in described drying steps, ethanol is reclaimed using vacuum distillation mode first,
Mucus is obtained, then mucus is dried, obtains extract;
Preferably, dry temperature is 85 DEG C~105 DEG C.
It should be noted that the mode of operation of recovery ethanol is evaporated under reduced pressure, can be according to the operation of existing recovery ethanol
Condition is carried out, and is just not described in detail herein.
In a kind of specific embodiment, alternatively, the temperature that mucus is dried be 85 DEG C, 86 DEG C, 87 DEG C, 88
℃、89℃、90℃、91℃、92℃、93℃、94℃、95℃、96℃、97℃、98℃、99℃、100℃、101℃、102℃、
103 DEG C, 104 DEG C or 105 DEG C.
So, by the mode of operation of above-mentioned crushing, alcohol extracting and drying, the active ingredient of raw material is enabled to obtain more
Good enrichment, while there is the characteristics of water-soluble strong, purity is high and has stablized again.
The third aspect, the detoxifying health-care product that present embodiment provides described in more than one are being prepared with stool of dispelling, row's intestines
Application in the medicine of poison, strengthening the spleen and stomach and/or clearing lung-heat expectoration effect.
The detoxifying health-care product that present embodiment provides, which are applied preparing, has stool of dispelling, expelling intestinal toxin, strengthening the spleen and stomach and/or clear
In the medicine of lung expectoration effect, unnecessary side effect will not be brought to body, product purity is high, and stability is good, instant
It is again quick, for excluding the toxin in vivo in the dirty insidious and blood of each internal organs, nourishing yin and nourishing blood, cleaning intestines product, stool of dispelling clearly, gut purge
Toxin expelling, balance internal organs etc. plays the role of positive.
With reference to specific embodiment and comparative example, the invention will be further described.
Embodiment 1-4
A kind of detoxifying health-care product, are prepared according to the ratio of the parts by weight of the raw material shown in table 1.
The embodiment 1-4 detoxifying health-care product formulas of table 1
Raw material | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 |
Radix glycyrrhizae | 40 parts | 50 parts | 70 parts | 80 parts |
Ginkgo leaf | 40 parts | 50 parts | 65 parts | 80 parts |
Rhizoma alismatis | 5 parts | 8 parts | 9 parts | 15 parts |
Oriental wormwood | 5 parts | 7 parts | 8 parts | 12 parts |
Turmeric | 6 parts | 10 parts | 11 parts | 16 parts |
Lotus leaf | 40 parts | 50 parts | 65 parts | 80 parts |
The fruit of Chinese wolfberry | 12 parts | 18 parts | 19 parts | 24 parts |
Peach kernel | 10 parts | 13 parts | 14 parts | 18 parts |
Dark plum | 15 parts | 20 parts | 22 parts | 30 parts |
Spina date seed | 15 parts | 20 parts | 22 parts | 30 parts |
Ginseng | 10 parts | 15 parts | 17 parts | 25 parts |
Pilose antler | 5 parts | 8 parts | 9 parts | 15 parts |
Hippocampus | 5 parts | 8 parts | 9 parts | 15 parts |
Ganoderma lucidum | 10 parts | 12 parts | 14 parts | 18 parts |
Ligusticum wallichii | 5 parts | 8 parts | 9 parts | 15 parts |
The bighead atractylodes rhizome | 5 parts | 8 parts | 9 parts | 15 parts |
Sealwort | 2 parts | 5 parts | 7 parts | 12 parts |
Radix bupleuri | 2 parts | 5 parts | 7 parts | 12 parts |
The root of herbaceous peony | 2 parts | 5 parts | 6 parts | 12 parts |
Rascal | 2 parts | 5 parts | 6 parts | 12 parts |
Radix Angelicae Sinensis | 2 parts | 2 parts | 2 parts | 12 parts |
Corn stigma | 5 parts | 8 parts | 9 parts | 15 parts |
Root tuber of aromatic turmeric | 5 parts | 8 parts | 9 parts | 15 parts |
Herba Lycopi | 15 parts | 8 parts | 9 parts | 15 parts |
Embodiment 5-8
The preparation method of detoxifying health-care product described in embodiment 1-4, comprises the following steps:
(a) first each raw material is cleaned, then is then crushed to obtain powder with mortar by each raw material stoving to constant weight respectively
The raw material of last shape;
Wherein, the drying temperature of radix glycyrrhizae and ginkgo leaf is 101 DEG C, and the drying temperature of rhizoma alismatis, oriental wormwood and turmeric is 103 DEG C,
The drying temperature of the fruit of Chinese wolfberry and peach kernel is 99 DEG C, and the drying temperature of ginseng and pilose antler is 97 DEG C, the baking of lotus leaf, dark plum and spina date seed
Dry temperature is 98 DEG C, and hippocampus, ganoderma lucidum, Ligusticum wallichii, the bighead atractylodes rhizome, corn stigma, the drying temperature of root tuber of aromatic turmeric and Herba Lycopi are 104 DEG C, sealwort, bavin
Recklessly, the drying temperature of the root of herbaceous peony, rascal and Radix Angelicae Sinensis is 105 DEG C;The granularity that each raw material crushes is 80 mesh.
(b) each raw material after a certain amount of crushing is weighed respectively, is placed in Soxhlet extraction device, is then added volume
Concentration is 85% each raw material of ethanol solution heating and refluxing extraction, obtains each extract solution;
Wherein, the number of the heating and refluxing extraction of radix glycyrrhizae and ginkgo leaf is 2 times, and the time of each refluxing extraction is 2 hours,
Reflux temperature is 90 DEG C, and the quality of raw material and the volume ratio of ethanol solution are 1:20;
The number of the heating and refluxing extraction of rhizoma alismatis, oriental wormwood and turmeric is 3 times, and the time of each refluxing extraction is 1 hour, is returned
It is 93 DEG C to flow temperature, and the quality of raw material and the volume ratio of ethanol solution are 1:25;
The number of the heating and refluxing extraction of the fruit of Chinese wolfberry and peach kernel is 2 times, and the time of each refluxing extraction is 3 hours, backflow
Temperature is 85 DEG C, and the quality of raw material and the volume ratio of ethanol solution are 1:30;
Ginseng, pilose antler, lotus leaf, the number of heating and refluxing extraction of dark plum and spina date seed are 1 time, and the time of refluxing extraction is
3 hours, reflux temperature was 96 DEG C, and the quality of raw material and the volume ratio of ethanol solution are 1:10;
The number of the heating and refluxing extraction of remaining raw material is 2 times, and the time of each refluxing extraction is 2 hours, reflux temperature
For 92 DEG C, the quality of raw material and the volume ratio of ethanol solution are 1:20.
(c) each extract solution is used to the recovery ethanol of vacuum distillation mode, mucus is obtained, then mucus is dried,
Dry temperature is 90 DEG C, obtains each extract;
(d) each extract is mixed according to formula rate, after being well mixed, detoxifying health-care product, the detoxifying health-care product is made
Formulation be oral liquid.
Embodiment 9
The preparation method of detoxifying health-care product described in embodiment 3, comprises the following steps:
(a) first each raw material is cleaned, then is then crushed to obtain powder with mortar by each raw material stoving to constant weight respectively
The raw material of last shape;
Wherein, the drying temperature of radix glycyrrhizae, ginkgo leaf, rhizoma alismatis, oriental wormwood and turmeric is 102 DEG C, the fruit of Chinese wolfberry, peach kernel, ginseng, deer
Young pilose antler, lotus leaf, the drying temperature of dark plum and spina date seed are 98 DEG C, hippocampus, ganoderma lucidum, Ligusticum wallichii, the bighead atractylodes rhizome, corn stigma, root tuber of aromatic turmeric, Herba Lycopi, Huang
Essence, radix bupleuri, the root of herbaceous peony, the drying temperature of rascal and Radix Angelicae Sinensis are 107 DEG C;The granularity that each raw material crushes is 60 mesh.
(b) each raw material after a certain amount of crushing is weighed respectively, is placed in Soxhlet extraction device, is then added volume
Concentration is 80% each raw material of ethanol solution heating and refluxing extraction, obtains each extract solution;
Wherein, the number of the heating and refluxing extraction of rhizoma alismatis, oriental wormwood and turmeric is 3 times, and the time of each refluxing extraction is 1.5
Hour, reflux temperature is 95 DEG C, and the quality of raw material and the volume ratio of ethanol solution are 1:30;
The number of the heating and refluxing extraction of the fruit of Chinese wolfberry and peach kernel is 1 time, and the time of each refluxing extraction is 2.5 hours, is returned
It is 92 DEG C to flow temperature, and the quality of raw material and the volume ratio of ethanol solution are 1:15;
Ginseng, pilose antler, lotus leaf, the number of heating and refluxing extraction of dark plum and spina date seed are 3 times, and the time of refluxing extraction is
1 hour, reflux temperature was 98 DEG C, and the quality of raw material and the volume ratio of ethanol solution are 1:22;
The number of the heating and refluxing extraction of remaining raw material is 2 times, and the time of each refluxing extraction is 2 hours, reflux temperature
For 90 DEG C, the quality of raw material and the volume ratio of ethanol solution are 1:20.
Step (c) and (d) are same as Example 7.
Embodiment 10
The preparation method of detoxifying health-care product described in embodiment 3, as different from Example 9 step (c) and (d).
(c) each extract solution is used to the recovery ethanol of vacuum distillation mode, mucus is obtained, then mucus is dried,
Dry temperature is 100 DEG C, obtains each extract;
(d) each extract is mixed according to formula rate, after being well mixed, detoxifying health-care product, the detoxifying health-care product is made
Formulation be granule.
Embodiment 11
The preparation method of detoxifying health-care product described in embodiment 2, as different from Example 6, the agent of the detoxifying health-care product
Type is pulvis.
Embodiment 12
The preparation method of detoxifying health-care product described in embodiment 2, as different from Example 6, the agent of the detoxifying health-care product
Type is tablet.
Comparative example 1
A kind of detoxifying health-care product, in parts by weight, not including ginkgo leaf, other raw materials are the same as embodiment 3.
The preparation method of the detoxifying health-care product is the same as embodiment 7.
Comparative example 2
A kind of detoxifying health-care product, in parts by weight, not including lotus leaf, other raw materials are the same as embodiment 3.
The preparation method of the detoxifying health-care product is the same as embodiment 7.
Comparative example 3
A kind of detoxifying health-care product, in parts by weight, not including corn stigma, root tuber of aromatic turmeric and Herba Lycopi, other raw materials are the same as implementation
Example 3.
The preparation method of the detoxifying health-care product is the same as embodiment 7.
Comparative example 4
A kind of detoxifying health-care product, are made up of the raw material of following parts by weight:
100 parts of radix glycyrrhizae, 90 parts of ginkgo leaf, 16 parts of rhizoma alismatis, 13 parts of oriental wormwood, 20 parts of turmeric, 85 parts of lotus leaf, 30 parts of the fruit of Chinese wolfberry,
It is 25 parts of peach kernel, 50 parts of dark plum, 50 parts of spina date seed, 28 parts of ginseng, 16 parts of pilose antler, 20 parts of hippocampus, 20 parts of ganoderma lucidum, 30 parts of Ligusticum wallichii, white
20 parts of art, 13 parts of sealwort, 13 parts of radix bupleuri, 14 parts of the root of herbaceous peony, 15 parts of rascal, 14 parts of Radix Angelicae Sinensis, 18 parts of corn stigma, 18 parts of root tuber of aromatic turmeric and Herba Lycopi
18 parts.
Comparative example 5
A kind of detoxifying health-care product of the prior art, are made up of the raw material of following parts by weight:20 parts of semen astragali complanati, stinkweed 15
Part, 10 parts of the bark of eucommia, 16 parts of the fleece-flower root, 6 parts of Fruit of Catalpa Ovata G. Don and 12 parts of mung bean.
Comparative example 6
The preparation method of detoxifying health-care product described in embodiment 3, it is as different from Example 9, unified to dry all raw materials,
Drying temperature is 100 DEG C;
All raw materials of unified alcohol extracting, the number of its heating and refluxing extraction is 2 times, and the time of each refluxing extraction is 2 hours,
Reflux temperature is 92 DEG C, and the gross mass of raw material and the volume ratio of ethanol solution are 1:20.
Comparative example 7
Detoxifying health-care product described in embodiment 3 are prepared using the preparation method of prior art, comprised the following steps:
Add in distilling kettle after all starting material with water are soaked, after being boiled by fire, be boiled with soft fire 30 minutes;Boiling twice, so
After filter, merge filtrate twice, be well mixed, obtain the detoxifying health-care product.
In order to verify the detoxifying health-care product of embodiment 5-10 and comparative example 1-7 offers in stool of dispelling, expelling intestinal toxin etc.
Effect, has carried out following clinical test.Poor appetite, indigestion, abdominal distention, the stagnant intestines of stool, intestines poison delay etc. is sub- strong
The people of health Disease 1300 (M-F 1:1, average age 38 years old), stochastic averagina is divided into 13 groups, corresponds to and uses embodiment 5-
The detoxifying health-care product of 10 and comparative example 1-7 offer.Once a day, each dosage is 20mL, after one week, two weeks, is seen
Log is examined, as shown in table 2.
The result of the test of table 2
Standard declaration is as follows:Healing refers to that the clinical symptoms such as the stagnant intestines of abdominal distention, stool are wholly absent;Effectively refer to gastral cavity abdomen
The clinical symptoms such as the stagnant intestines of distending pain, stool have been alleviated, but effect is not wholly absent.
As shown in Table 2, embodiment 5-10 effect of ejecting poison is substantially better than comparative example 1-7, and especially embodiment 7 is provided
Detoxifying health-care product, therapeutic effect more preferably, using cure rate after one week can reach 85%, and effective percentage can reach 90%, use two weeks
Cure rate and effective percentage reach 100% afterwards.Thus explanation is using the detoxifying health-care product of the present invention, and for exclusion, each internal organs is dirty in vivo
Insidious and blood in toxin, nourishing yin and nourishing blood, cleaning intestines product, stool of dispelling clearly, detoxicating intestine, balance internal organs etc. have significant
Effect.
From the comparative analysis of comparative example 1-4 and embodiment 7, change the proportioning of each raw material in detoxifying health-care product so that
The proportioning of raw material is not in the scope of protection of the invention, or deletes any one component or various ingredients therein, can not
Realize the effect above, effect of ejecting poison is poor.Comparative example 1-3 is also further illustrated, ginkgo leaf, lotus selected by the present invention
Mutual cooperation effect between the raw materials such as leaf, corn stigma, root tuber of aromatic turmeric, Herba Lycopi, wherein, ginkgo leaf or lotus leaf can be with other raw material groups
Divide collaboration promotion, efficiently play the effect that toxin expelling is cleaned, stimulated circulation, can more meet the needs of patient, realize accurate, high
Effect, safety and quickly effect of ejecting poison.
From the comparative analysis of comparative example 5 and embodiment 7, using detoxifying health-care product provided by the invention, for gastral cavity abdomen
The therapeutic effect of the patients such as the stagnant intestines of distending pain, stool is better than existing common expellant medicament therapeutic effect.By comparative example 6,7 and in fact
The comparative analysis for applying example 7 is understood, the preparation method of detoxifying health-care product provided by the invention, can more give full play to the work(of each raw material
Effect so that effective nutritional ingredient of each raw material has obtained more preferable enrichment, reduces the invalid components in medicine, reduces residue
Infringement caused by confrontation human body, safe to use, therapeutic effect is good.
Typical case:
1st, Mrs Huang, 40 years old, Guangzhou bank lobby manager, shortness of breath uncomfortable in chest often, sleep often suppressed awake, no gas of speaking
Power, double knees suffer from synovitis, the long waist and leg ache of stand up time again, and head swoons failure of memory all day long.Take the present invention
After the detoxifying health-care product of offer, from night 9 points 30 minutes or so to 10 points or so of the next morning common defecation more than 10 times, in watery stool
There is the particle that green, yellow differ in size, each time with red small patch, body is a bit apprehensive when just drained, and stomach is slightly uncomfortable,
Second day these symptom disappear, and breathing is smooth, and not only spirit has from head to foot also energetically people, on foot especially easily, oneself description
As having changed individual, life from now on is full of confidence.
2nd, Mrs Qin, 45 years old, Chongqing City's hospital doctor, brain blood supply in recent years and myocardial blood supply are bad always, frequent chest
Sulks are short, also suffer from duodenal ulcer, cholecystitis, kidney stone, pelvic infecton, fibroid, rheumatism etc., take the present invention and carry
After the detoxifying health-care product of confession, that night 9: 10 separately begins to 30 minutes the next mornings 10 point common defecation 15 times, and black fungus shape thing is most
It is more, also blackish green spherical particle, yellow corn scoriform etc..Of pink and healthy-looking, stomach, intestines, gall-bladder are uncomfortable after drained disappears, in the past from
Do not perspire, perspire now normal, the blood vessel extravasated blood caused by injury is moved back on increased weight 3 kilograms (partially thin in the past), a left side after one month
Distending pain disappears.
3rd, Mr. Chen, 35 years old, Zhejiang schoolman, prolonged constipation, face acnes, enterotoxin accumulation is excessive, enteron aisle
And skin toxin expelling is not smooth, after taking detoxifying health-care product provided by the invention, same day defecation 6 times, after taking one week, constipation symptom obtains
To the preferable effect alleviated, daily normal defecation is reached after taking two weeks, constipation symptom disappears, and acne substantially mitigates.
Finally it should be noted that:Various embodiments above is merely illustrative of the technical solution of the present invention, rather than its limitations;To the greatest extent
The present invention is described in detail with reference to foregoing embodiments for pipe, it will be understood by those within the art that:Its according to
The technical scheme described in foregoing embodiments can so be modified, either which part or all technical characteristic are entered
Row equivalent substitution;And these modifications or replacement, the essence of appropriate technical solution is departed from various embodiments of the present invention technology
The scope of scheme.
Claims (10)
1. a kind of detoxifying health-care product, it is characterised in that be mainly made up of the raw material of following parts by weight:
40~80 parts of radix glycyrrhizae, 40~80 parts of ginkgo leaf, 5~15 parts of rhizoma alismatis, 5~12 parts of oriental wormwood, 6~16 parts of turmeric, lotus leaf 40~
80 parts, 12~24 parts of the fruit of Chinese wolfberry, 10~18 parts of peach kernel, 15~30 parts of dark plum, 15~30 parts of spina date seed, 10~25 parts of ginseng, deer
Fine and soft 5~15 parts, 5~15 parts of hippocampus, 10~18 parts of ganoderma lucidum, 5~15 parts of Ligusticum wallichii, 5~15 parts of the bighead atractylodes rhizome, 2~12 parts of sealwort, radix bupleuri 2
~12 parts, 2~12 parts of the root of herbaceous peony, 2~12 parts of rascal, 2~12 parts of Radix Angelicae Sinensis, 5~15 parts of corn stigma, 5~15 parts of root tuber of aromatic turmeric and Herba Lycopi 5~
15 parts.
2. detoxifying health-care product according to claim 1, it is characterised in that be mainly made up of the raw material of following parts by weight:
50~70 parts of radix glycyrrhizae, 50~70 parts of ginkgo leaf, 8~10 parts of rhizoma alismatis, 7~9 parts of oriental wormwood, 10~12 parts of turmeric, lotus leaf 50~
70 parts, 18~20 parts of the fruit of Chinese wolfberry, 13~15 parts of peach kernel, 20~25 parts of dark plum, 20~25 parts of spina date seed, 15~20 parts of ginseng, deer
Fine and soft 8~10 parts, 8~10 parts of hippocampus, 12~15 parts of ganoderma lucidum, 8~10 parts of Ligusticum wallichii, 8~10 parts of the bighead atractylodes rhizome, 5~8 parts of sealwort, radix bupleuri 5~
8~10 parts of 8 parts, 5~8 parts of the root of herbaceous peony, 5~8 parts of rascal, 5~8 parts of Radix Angelicae Sinensis, 8~10 parts of corn stigma, 8~10 parts of root tuber of aromatic turmeric and Herba Lycopi.
3. detoxifying health-care product according to claim 1, it is characterised in that be mainly made up of the raw material of following parts by weight:
55~65 parts of radix glycyrrhizae, 55~65 parts of ginkgo leaf, 8.5~9.5 parts of rhizoma alismatis, 7.5~8.5 parts of oriental wormwood, turmeric 10.5~11.5
Part, 55~65 parts of lotus leaf, 18.5~19.5 parts of the fruit of Chinese wolfberry, 13.5~14.5 parts of peach kernel, 21~23 parts of dark plum, spina date seed 21~23
It is part, 16~18 parts of ginseng, 8.5~9.5 parts of pilose antler, 8.5~9.5 parts of hippocampus, 13~14 parts of ganoderma lucidum, 8.5~9.5 parts of Ligusticum wallichii, white
8.5~9.5 parts of art, 6~7 parts of sealwort, 6~7 parts of radix bupleuri, 6~7 parts of the root of herbaceous peony, 6~7 parts of rascal, 6~7 parts of Radix Angelicae Sinensis, corn stigma 8.5
8.5~9.5 parts of~9.5 parts, 8.5~9.5 parts of root tuber of aromatic turmeric and Herba Lycopi.
4. the detoxifying health-care product according to any one of claims 1 to 3, it is characterised in that the formulation of the detoxifying health-care product
For oral formulations.
5. detoxifying health-care product according to claim 4, it is characterised in that the formulation of the detoxifying health-care product is tablet, glue
Wafer, granule, pill, pulvis or oral liquid.
6. the preparation method of the detoxifying health-care product as described in any one of Claims 1 to 5, it is characterised in that methods described includes
Following steps:
Each raw material is crushed respectively, alcohol extracting and drying, obtain each extract;
Each extract is mixed according to formula rate, the detoxifying health-care product are made.
7. the preparation method of detoxifying health-care product according to claim 6, it is characterised in that first in described pulverising step
Raw material is first dried to constant weight at 90 DEG C~115 DEG C, is then crushed to obtain powdered raw material with mortar;
Preferably, the temperature of drying is 100 DEG C~105 DEG C;
Preferably, the granularity of crushing is the mesh of 60 mesh~80.
8. the preparation method of the detoxifying health-care product according to claim 6 or 7, it is characterised in that in described alcohol extracting step,
The raw material after crushing is weighed first, is placed in extraction element, and it is 75%~90% ethanol solution then to add volumetric concentration
Heating and refluxing extraction 1~3 time, the time of each refluxing extraction is 1~3 hour, and reflux temperature is 85 DEG C~98 DEG C, the matter of raw material
Amount and the volume ratio of ethanol solution are 1:10~30;
Preferably, the extraction element is apparatus,Soxhlet's;
Preferably, the volumetric concentration of the ethanol solution is 80%~85%;
Preferably, the time of each refluxing extraction is 2~2.5 hours, and reflux temperature is 88 DEG C~90 DEG C, the quality and second of raw material
The volume ratio of alcoholic solution is 1:20~22.
9. the preparation method of detoxifying health-care product according to claim 8, it is characterised in that first in described drying steps
Ethanol is first reclaimed using vacuum distillation mode, mucus is obtained, then mucus is dried, obtain extract;
Preferably, dry temperature is 85 DEG C~105 DEG C.
10. detoxifying health-care product according to any one of claims 1 to 5 prepare have dispel stool, expelling intestinal toxin, strengthening the spleen and stomach and/
Or the application in the medicine of clearing lung-heat expectoration effect.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710709534.5A CN107412679A (en) | 2017-08-17 | 2017-08-17 | Detoxifying health-care product and its preparation method and application |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710709534.5A CN107412679A (en) | 2017-08-17 | 2017-08-17 | Detoxifying health-care product and its preparation method and application |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107412679A true CN107412679A (en) | 2017-12-01 |
Family
ID=60433977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710709534.5A Pending CN107412679A (en) | 2017-08-17 | 2017-08-17 | Detoxifying health-care product and its preparation method and application |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107412679A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110090250A (en) * | 2019-04-18 | 2019-08-06 | 明安旭(上海)健康科技有限公司 | It is a kind of lose weight and detoxicating intestine composition and preparation method thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104740541A (en) * | 2015-04-21 | 2015-07-01 | 杨波 | Health-care traditional Chinese medicine powder for protecting liver, detoxifying and recovering liver functions |
CN105727145A (en) * | 2016-04-12 | 2016-07-06 | 青岛市市立医院 | Traditional Chinese medicine drug for treating spleen deficiency phlegm-dampness syndrome type hyperlipidaemia |
-
2017
- 2017-08-17 CN CN201710709534.5A patent/CN107412679A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104740541A (en) * | 2015-04-21 | 2015-07-01 | 杨波 | Health-care traditional Chinese medicine powder for protecting liver, detoxifying and recovering liver functions |
CN105727145A (en) * | 2016-04-12 | 2016-07-06 | 青岛市市立医院 | Traditional Chinese medicine drug for treating spleen deficiency phlegm-dampness syndrome type hyperlipidaemia |
Non-Patent Citations (1)
Title |
---|
ZHUKANG64: ""圣草净——健康排毒专家"", 《HTTP://BLOG.SINA.COM.CN/S/BLOG_69FDC4C70100SLQU.HTML》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110090250A (en) * | 2019-04-18 | 2019-08-06 | 明安旭(上海)健康科技有限公司 | It is a kind of lose weight and detoxicating intestine composition and preparation method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103689171A (en) | Healthcare tea capable of tonifying qi, tonifying spleen and tonifying kidney | |
CN109966462A (en) | A kind of herbal paste and preparation method thereof improving constitution | |
CN105664099A (en) | Traditional Chinese medicine composition for warming and invigorating kidney yang and preparation method thereof | |
CN104069474B (en) | Traditional Chinese medicine composition for treating seborrheic alopecia and preparation method thereof | |
CN102526496B (en) | Traditional Chinese medicine composition for treating fire excess from yin deficiency type sleepless night sweating symptoms, and preparation method of traditional Chinese medicine composition | |
CN103860773A (en) | Traditional Chinese medicine composition for treating myocardial ischemia and preparation method thereof | |
CN107412679A (en) | Detoxifying health-care product and its preparation method and application | |
CN103844164A (en) | Qi-tonifying and blood-nourishing porridge and preparation method thereof | |
CN105641330A (en) | Traditional Chinese medicine composition for invigorating kidney and strengthening yang | |
CN105641466A (en) | Traditional Chinese medicine composition for invigorating kidney and strengthening yang and preparing method thereof | |
CN105250569A (en) | Traditional Chinese medicine pill for treating peripheral neuritis and preparation method | |
CN104857370A (en) | Traditional Chinese medicine composition for treating breast cancer | |
CN104306583A (en) | Traditional Chinese medicine composition for treating scanty menstruation and preparation method of traditional Chinese medicine composition | |
CN104043058A (en) | Traditional Chinese medicinal preparation for treating kidney deficiency type lumbar disc herniation and preparation method thereof | |
CN105998469A (en) | Traditional Chinese medicine preparation for treating hypersomnia and preparation method | |
CN105561101A (en) | Traditional Chinese medicine preparation for treating phthisis and preparation method thereof | |
CN105362940A (en) | Hypolipidemic cholesterol-reducing healthcare oral solution and preparation method thereof | |
CN105617388A (en) | Kidney-tonifying yang-strengthening medicine composition | |
CN104667107A (en) | Medicine for treating summerheat injuring lung and stomach summer fever in children and preparation method of medicine | |
CN105412322A (en) | Traditional Chinese medicine preparation for treating diabetic peripheral neuropathic pain and preparation method thereof | |
CN105147861A (en) | Traditional Chinese medicinal composition and oral preparation for treating viral skin diseases and preparation method of oral preparation | |
CN105343474A (en) | Capsules for treating male climacteric syndromes and preparation method | |
CN104758889A (en) | Traditional Chinese medicine composition for treating diabetes | |
CN104840814A (en) | Traditional Chinese medicine combination for treating senile femoral head necrosis | |
CN104758888A (en) | Traditional Chinese medicine composition for treating diabetes |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171201 |