CN106344443A - Caring type toothpaste and preparation method thereof - Google Patents
Caring type toothpaste and preparation method thereof Download PDFInfo
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- CN106344443A CN106344443A CN201610717970.2A CN201610717970A CN106344443A CN 106344443 A CN106344443 A CN 106344443A CN 201610717970 A CN201610717970 A CN 201610717970A CN 106344443 A CN106344443 A CN 106344443A
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- Prior art keywords
- toothpaste
- maintaining
- thickening agent
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- mass percent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention provides caring type toothpaste, which is prepared from the following ingredients in percentage by mass: 20 to 35 percent of erigeron breviscapus extracts, 2 to 5 percent of thickening agents, 1 to 3 percent of chitosan, 10 to 18 percent of glycerin, 5 to 8 percent of coconut oil alcohol acylamide, 13 to 20 percent of calcium hydrophosphate dehydrate, 1500 to 2000 units ofprotease in per gram of paste and the balance deionized water. The caring type toothpaste has the obvious effects of relieving pain and inflammation and preventing periodontitis, gingivitis, ozostomia, saprodontia and dental ulcer; meanwhile, the caring type toothpaste is also particularly applicable to high-risk patient groups with cerebrovascular diseases and the like; the cost is low; in addition, due to the characteristics of wide distribution and low price of the erigeron breviscapus, the cost for producing the medicine paste can be effectively reduced.
Description
Technical field
The present invention relates to daily-use chemical industry abluent field, particularly to a kind of maintaining toothpaste and preparation method thereof.
Background technology
Toothpaste is conventional cleaning supplies in daily life, has very long history.Constantly send out with scientific and technical
Exhibition, the updating and perfect of technological equipment, various types of toothpaste are come out one after another, and the quality of product and class improve constantly,
Now toothpaste variety, by single clean type toothpaste, develops into great variety of goods, vdiverse in function, up to a hundred brands multi-functional
Type toothpaste, meets the needs of different levels level of consumption.
Content of the invention
The present invention, in order to make up the problems referred to above, provides a kind of maintaining toothpaste and preparation method, and has no side effect.
The present invention proposes a kind of maintaining toothpaste, calculates according to mass percent, and the Herba Erigerontiss including 20%-35% carry
Take thing, the thickening agent of 2%-5%, the shitosan of 1%-3%, the glycerol of 10%-18%, the Oleum Cocois alkylolamides of 5%-8%,
Calcium hydrogen phosphate two hydrate of 13%-20%, every gram of mastic of protease 1500～2000 unit, balance of deionized water.
Preferably, described toothpaste also contains and calculates as 3%-8% sodium laurylsulfate according to mass percent.
Preferably, described toothpaste also contains and calculates as 5%-15% Sorbitol according to mass percent.
Preferably, calculate according to mass percent, calculate according to mass percent, the Herba Erigerontiss including 25% extract
Thing, 2% thickening agent, 3% shitosan, 16% glycerol, 8% Oleum Cocois alkylolamides, 13% calcium hydrogen phosphate two aquation
Compound, every gram of mastic of protease 1500 unit, balance of deionized water.
Preferably, calculate according to mass percent, including 30% Herba Erigerontis extract, 3% thickening agent, 3%
Shitosan, 15% glycerol, 6% Oleum Cocois alkylolamides, 15% calcium hydrogen phosphate two hydrate, every gram of mastic of protease
2000 units, balance of deionized water.
Preferably, described thickening agent be sodium carboxymethyl cellulose, hydroxyethyl cellulose, any one in carbomer.
The present invention also proposes a kind of preparation method of above-mentioned maintaining toothpaste, and it comprises the steps:
S10, thickening agent is put into heating in deionized water；
S20, weighs the Herba Erigerontis extract of respective quality ratio, thickening agent, shitosan, glycerol, Oleum Cocois alkylolamides, egg
White enzyme adds in the solution that s10 obtains, and stirs, is allowed to emulsifying complete；
S30, the solution of step s20 configuration is mixed with calcium hydrogen phosphate two hydrate powder, upper three roll machine grinds to form thin cream
Shape；
S40, is filled with paste filling machine or people's frock and is commercial goods.
The maintaining toothpaste drug effect of the present invention is wide, has obvious anti-inflammatory analgetic, pre- preventing parodontitis, gingivitiss, halitosis, dental caries
Tooth, effect of oral ulcer, are also particularly suitable the excessive risk patient groups such as cerebrovascular simultaneously；Low cost, additionally due to lamp
Widely distributed, the cheap feature of small cup Herba Asari, can be effectively reduced the cost producing this medicated toothpaste.
Specific embodiment
It should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention
Scope.
The present invention proposes a kind of maintaining toothpaste, calculates according to mass percent, and the Herba Erigerontiss including 20%-35% carry
Take thing, the thickening agent of 2%-5%, the shitosan of 1%-3%, the glycerol of 10%-18%, the Oleum Cocois alkylolamides of 5%-8%,
Calcium hydrogen phosphate two hydrate of 13%-20%, every gram of mastic of protease 1500～2000 unit, balance of deionized water.
Preferably, described toothpaste also contains and calculates as 3%-8% sodium laurylsulfate according to mass percent.
Preferably, described toothpaste also contains and calculates as 5%-15% Sorbitol according to mass percent.
Preferably, calculate according to mass percent, including 25% Herba Erigerontis extract, 2% thickening agent, 3%
Shitosan, 16% glycerol, 8% Oleum Cocois alkylolamides, 13% calcium hydrogen phosphate two hydrate, every gram of mastic of protease
1500 units, balance of deionized water.
Preferably, calculate according to mass percent, including 30% Herba Erigerontis extract, 3% thickening agent, 3%
Shitosan, 15% glycerol, 6% Oleum Cocois alkylolamides, 15% calcium hydrogen phosphate two hydrate, every gram of mastic of protease
2000 units, balance of deionized water.
Specifically, in the present embodiment, described thickening agent is sodium carboxymethyl cellulose, in other embodiments, described increasing
Thick dose can also be hydroxyethyl cellulose or carbomer.It can be with the food debriss of residual and dirt on effective cleaning tooth.
Make mastic uniformity, surfacing is smooth.
Herba Erigerontiss, Classification system herbaerigerontis, Compositae Herba Erigerontis aceris platymiscium Erigeron breviscapus (Vant.) Hand.-Mazz., entered with herb or root
Medicine.The flowers are in blossom harvesting when putting that autumn stem and leaf is luxuriant, cleans, using fresh herb or dry.Nature and flavor are pungent, slight bitter, temperature.Can expelling cold and relieving exterior syndrome, wind-dispelling removes
Wet, activating collaterals to relieve pain.For headache due to common cold, have a toothache, stomachache, rheumatalgia, the paralysis that cerebrovas-cularaccident causes, osteomyelitis.Clinical
Research shows: Herba Erigerontiss are for treatment hypertensive cerebral hemorrhage, cerebral thrombosiss, cerebral embolism, polyneuritiss, chronic spider web
, there is certain curative effect in film Yan Denghouyi paralysed disease.
The xeraphium of Herba Erigerontis extract is all through conventional ethanol extraction side by its crude drug with ethanol for solvent
After method obtains ethanol extraction, it is dried and obtains extract powder.Conventional alcohol extraction procedure has: cold-maceration, percolation, backflow
Method, ultrasonic method etc..After effective ingredient also can be dissolved by the xeraphium of Herba Erigerontis extract by crude drug decocting cooking method, it is dried
Obtain extract powder.But the extracts active ingredients of decocting cooking method are less efficient.
Herba Erigerontiss are widely distributed in mountain and the open patana of Subalpine region and border in China western part and the west and south, and price is only
It is about the 15% about of Radix Notoginseng.So far not yet have and Herba Erigerontiss are used as the research of Chinese herbs composition or application in toothpaste
Report.
Oleum Cocois alkylolamides can be strengthened cleaning effect, can be used as additive, foam tranquilizer, foaming aidses, is mainly used in perfume (or spice)
Involve the manufacture of liquid detergent.Form a kind of opaque cloudy solution in water, can be fully transparent under certain stirring,
Can be dissolved completely under finite concentration in different types of surfactant, also can be completely dissolved in low-carbon (LC) and high-carbon.
The present invention also proposes a kind of preparation method of above-mentioned maintaining toothpaste, and it comprises the steps:
S10, thickening agent is put into heating in deionized water；
S20, adds Herba Erigerontis extract, shitosan, glycerol, Oleum Cocois alkylolamides toward in s10 solution, stirs,
It is allowed to emulsifying complete；
S30, the solution of step s20 configuration is mixed with calcium hydrogen phosphate two hydrate powder, upper three roll machine grinds to form thin cream
Shape；
S40, is filled with paste filling machine or people's frock and is commercial goods.
Maintaining toothpaste proposed by the present invention, increased glycerol, Oleum Cocois alkylolamides on the basis of existing formulation of tooth-paste
Etc. pneumostatic composition of calming the nerves, so that the effect of present invention had both had cleaning tooth, can effectively help for sleep simultaneously again.Simply have
Effect, has no side effect.
Embodiment 1
S10, sodium carboxymethyl cellulose 50g is put into heating in 300g deionized water；
S20, adds Herba Erigerontis extract 200g, shitosan 30g, glycerol 160g, Cortex cocois radiciss oleyl alcohol acyl toward in above-mentioned solution
Amine 80g, stirs, and is allowed to emulsifying complete；
S30, the solution of step s20 configuration is mixed with calcium hydrogen phosphate two hydrate powder 130g, upper three roll machine grinds to form
Thin paste；
S40, is filled with paste filling machine or people's frock and is commercial goods.
Embodiment 2
S10, hydroxyethyl cellulose 20g is put into heating in 490g deionized water；
S20, adds Herba Erigerontis extract 350g, shitosan 10g, glycerol 180g, Cortex cocois radiciss oleyl alcohol acyl toward in above-mentioned solution
Amine 50g, stirs, and is allowed to emulsifying complete；
S30, the solution of step s20 configuration is mixed with calcium hydrogen phosphate two hydrate powder 200g, upper three roll machine grinds to form
Thin paste；
S40, is filled with paste filling machine or people's frock and is commercial goods.
Embodiment 3
S10, carbomer 25g is put into heating in 110g deionized water；
S20, adds Herba Erigerontis extract 200g, shitosan 15g, glycerol 100g, Cortex cocois radiciss oleyl alcohol acyl toward in above-mentioned solution
Amine 50g, Sorbitol 50g, sodium laurylsulfate 30g, stir, be allowed to emulsifying complete；
S30, the solution of step s20 configuration is mixed with calcium hydrogen phosphate two hydrate powder 180g, upper three roll machine grinds to form
Thin paste；
S40, is filled with paste filling machine or people's frock and is commercial goods.
By the toothpaste in above-described embodiment, under show the patient of different symptoms and try out, sleep front use every night, continue three
Week.Result is as follows:
From above-mentioned data, the maintaining toothpaste drug effect of the present invention is wide, has obvious anti-inflammatory analgetic, prevents periodontal
Inflammation, gingivitiss, halitosis, dental caries, effect of oral ulcer, are also particularly suitable the excessive risk patient groups such as cerebrovascular simultaneously；
Low cost, additionally due to widely distributed, the cheap feature of Herba Erigerontiss, can be effectively reduced and produce this medicated toothpaste
Cost.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and
Within principle, any modification, equivalent substitution and improvement made etc., should be included within the scope of the present invention.
Claims (7)
1. it is characterised in that calculating according to mass percent, the Herba Erigerontiss including 20%-35% carry a kind of maintaining toothpaste
Take thing, the thickening agent of 2%-5%, the shitosan of 1%-3%, the glycerol of 10%-18%, the Oleum Cocois alkylolamides of 5%-8%,
Calcium hydrogen phosphate two hydrate of 13%-20%, every gram of mastic of protease 1500～2000 unit, balance of deionized water.
2. maintaining toothpaste as claimed in claim 1 is it is characterised in that described toothpaste also contains according to mass percent calculating
For 3%-8% sodium laurylsulfate.
3. maintaining toothpaste as claimed in claim 1 is it is characterised in that described toothpaste also contains according to mass percent calculating
For 5%-15% Sorbitol.
4. maintaining toothpaste as claimed in claim 1 is it is characterised in that calculate according to mass percent, including 25% lamp
Small cup Herba Asari extract, 2% thickening agent, 3% shitosan, 16% glycerol, 8% Oleum Cocois alkylolamides, 13% phosphoric acid
Hydrogen calcium two hydrate, every gram of mastic of protease 1500 unit, balance of deionized water.
5. maintaining toothpaste as claimed in claim 1 is it is characterised in that calculate according to mass percent, including 30% lamp
Small cup Herba Asari extract, 3% thickening agent, 3% shitosan, 15% glycerol, 6% Oleum Cocois alkylolamides, 15% phosphoric acid
Hydrogen calcium two hydrate, every gram of mastic of protease 2000 unit, balance of deionized water.
6. maintaining toothpaste as claimed in claim 1 is it is characterised in that described thickening agent is sodium carboxymethyl cellulose, hydroxyl second
Any one in base cellulose, carbomer.
7. the preparation method of the maintaining toothpaste described in a kind of any one of claim 1 to 6, comprises the following steps:
S10, thickening agent is put into heating in deionized water；
S20, weighs the Herba Erigerontis extract of respective quality ratio, thickening agent, shitosan, glycerol, Oleum Cocois alkylolamides, protease
Add in the solution that s10 obtains, stir, be allowed to emulsifying complete；
S30, the solution of step s20 configuration is mixed with calcium hydrogen phosphate two hydrate powder, upper three roll machine grinds to form thin paste；
S40, is filled with paste filling machine or people's frock and is commercial goods.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610717970.2A CN106344443A (en) | 2016-08-24 | 2016-08-24 | Caring type toothpaste and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610717970.2A CN106344443A (en) | 2016-08-24 | 2016-08-24 | Caring type toothpaste and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
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| CN106344443A true CN106344443A (en) | 2017-01-25 |
Family
ID=57844802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610717970.2A Pending CN106344443A (en) | 2016-08-24 | 2016-08-24 | Caring type toothpaste and preparation method thereof |
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| Country | Link |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107648145A (en) * | 2017-11-27 | 2018-02-02 | 钱卫萍 | A kind of toothpaste with white-skinned face function |
| CN107661271A (en) * | 2017-11-27 | 2018-02-06 | 钱卫萍 | A kind of inflammation-diminishing toothpaste |
| CN107669568A (en) * | 2017-11-27 | 2018-02-09 | 钱卫萍 | A kind of antibacterial toothpaste |
| CN107811919A (en) * | 2017-11-27 | 2018-03-20 | 钱卫萍 | A kind of toothpaste |
| CN107823050A (en) * | 2017-11-27 | 2018-03-23 | 钱卫萍 | A kind of Chinese herbal toothpaste |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101972220A (en) * | 2010-10-28 | 2011-02-16 | 深圳智慧天使投资有限公司 | Medicated toothpaste |
| CN104606092A (en) * | 2014-12-30 | 2015-05-13 | 东莞市高明企业服务有限公司 | Toothpaste capable of calming nerves and helping sleep for night use and preparation method thereof |
| CN104666120A (en) * | 2013-11-29 | 2015-06-03 | 无锡丝源化妆品有限公司 | Toothpaste |
-
2016
- 2016-08-24 CN CN201610717970.2A patent/CN106344443A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101972220A (en) * | 2010-10-28 | 2011-02-16 | 深圳智慧天使投资有限公司 | Medicated toothpaste |
| CN104666120A (en) * | 2013-11-29 | 2015-06-03 | 无锡丝源化妆品有限公司 | Toothpaste |
| CN104606092A (en) * | 2014-12-30 | 2015-05-13 | 东莞市高明企业服务有限公司 | Toothpaste capable of calming nerves and helping sleep for night use and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 裘炳毅等: "《现代化妆品科学与技术》", 31 March 2016, 中国轻工业出版社 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107648145A (en) * | 2017-11-27 | 2018-02-02 | 钱卫萍 | A kind of toothpaste with white-skinned face function |
| CN107661271A (en) * | 2017-11-27 | 2018-02-06 | 钱卫萍 | A kind of inflammation-diminishing toothpaste |
| CN107669568A (en) * | 2017-11-27 | 2018-02-09 | 钱卫萍 | A kind of antibacterial toothpaste |
| CN107811919A (en) * | 2017-11-27 | 2018-03-20 | 钱卫萍 | A kind of toothpaste |
| CN107823050A (en) * | 2017-11-27 | 2018-03-23 | 钱卫萍 | A kind of Chinese herbal toothpaste |
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