CN101855553A - 卵巢癌的预测标记 - Google Patents
卵巢癌的预测标记 Download PDFInfo
- Publication number
- CN101855553A CN101855553A CN200880101477A CN200880101477A CN101855553A CN 101855553 A CN101855553 A CN 101855553A CN 200880101477 A CN200880101477 A CN 200880101477A CN 200880101477 A CN200880101477 A CN 200880101477A CN 101855553 A CN101855553 A CN 101855553A
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- cancer
- oophoroma
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Abstract
Description
模型名称 | 特征 | 匹配 | 世代 | 节点 | I期灵敏度 | I期特异性 | I期准确性 | II期灵敏度 | III-IV期灵敏度 | 特异性 |
2_0008_20 | 4 | 0.9 | 20 | 12 | 75 | 100 | 87.5 | 60.9 | 46.5 | 82.6 |
4_0002_10 | 3 | 0.7 | 10 | 4 | 75 | 100 | 87.5 | 69.6 | 82.6 | 56 |
4_0009_140 | 5 | 0.6 | 140 | 5 | 75 | 100 | 87.5 | 43.5 | 39.5 | 71.6 |
4_0026_100 | 9 | 0.7 | 100 | 5 | 87.5 | 100 | 93.8 | 78.3 | 84.9 | 67 |
4_0027_20 | 9 | 0.8 | 20 | 5 | 87.5 | 100 | 93.8 | 78.3 | 84.9 | 60.6 |
Claims (20)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94725307P | 2007-06-29 | 2007-06-29 | |
US60/947,253 | 2007-06-29 | ||
US3794608P | 2008-03-19 | 2008-03-19 | |
US61/037,946 | 2008-03-19 | ||
PCT/US2008/068845 WO2009006439A1 (en) | 2007-06-29 | 2008-06-30 | Predictive markers for ovarian cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101855553A true CN101855553A (zh) | 2010-10-06 |
CN101855553B CN101855553B (zh) | 2014-06-11 |
Family
ID=40161028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200880101477.1A Expired - Fee Related CN101855553B (zh) | 2007-06-29 | 2008-06-30 | 卵巢癌的预测标记 |
Country Status (10)
Country | Link |
---|---|
US (5) | US8664358B2 (zh) |
EP (2) | EP2637020A3 (zh) |
JP (1) | JP2010532484A (zh) |
KR (2) | KR20120087885A (zh) |
CN (1) | CN101855553B (zh) |
BR (1) | BRPI0813002A2 (zh) |
CA (1) | CA2691980C (zh) |
MY (1) | MY150234A (zh) |
SG (1) | SG182976A1 (zh) |
WO (1) | WO2009006439A1 (zh) |
Cited By (13)
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CN102735840A (zh) * | 2011-04-13 | 2012-10-17 | 中国医学科学院肿瘤研究所 | 用于诊断或筛查卵巢癌的试剂 |
CN103582815A (zh) * | 2011-02-24 | 2014-02-12 | 佛米利昂公司 | 用于卵巢癌的生物标志物组、诊断方法和测试试剂盒 |
CN104251906A (zh) * | 2013-06-27 | 2014-12-31 | 清华大学 | 一种肿瘤标志物 |
CN104422768A (zh) * | 2013-08-30 | 2015-03-18 | 广州瑞博奥生物科技有限公司 | 一种联合检测早期卵巢癌标志物的抗体芯片试剂盒 |
CN104508485A (zh) * | 2013-06-07 | 2015-04-08 | 凯尔杰姆维克斯有限公司 | 在癌症免疫疗法中有用的生物标记 |
CN105745543A (zh) * | 2013-09-18 | 2016-07-06 | 阿德莱德研究及创新控股有限公司 | 卵巢癌的自身抗体生物标志物 |
CN105917230A (zh) * | 2013-11-11 | 2016-08-31 | 伊缪诺维亚公司 | 用于确定胰腺癌的方法、阵列和其用途 |
CN106520924A (zh) * | 2016-10-14 | 2017-03-22 | 浙江大学 | 一种用于检测卵巢癌的引物组及检测方法 |
CN108699605A (zh) * | 2015-06-03 | 2018-10-23 | 爱兰细胞技术公司 | 基于il-2的疗法和基于间充质干细胞的疗法的伴随方法和试剂盒 |
CN109116025A (zh) * | 2013-01-08 | 2019-01-01 | 斯弗因高泰克有限公司 | 预测受试者患癌症的风险或诊断癌症的方法 |
CN109481667A (zh) * | 2018-12-14 | 2019-03-19 | 上海卡序生物医药科技有限公司 | 转甲状腺素蛋白在抑制肿瘤血管新生中的应用 |
CN109946456A (zh) * | 2019-02-19 | 2019-06-28 | 中国农业科学院北京畜牧兽医研究所 | 牛结核病诊断标志物及其应用 |
CN111521807A (zh) * | 2020-07-02 | 2020-08-11 | 北京信诺卫康科技有限公司 | Spondin 1和CA125联合用作早期卵巢癌生物标志物以及试剂盒 |
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US20060078893A1 (en) * | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
US20050221339A1 (en) * | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
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WO2008021123A1 (en) | 2006-08-07 | 2008-02-21 | President And Fellows Of Harvard College | Fluorocarbon emulsion stabilizing surfactants |
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JP6115801B2 (ja) | 2007-03-27 | 2017-04-19 | イミュノヴィア・アーベー | 腺癌の検出のための蛋白質シグネチャー/マーカー |
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CN101942017B (zh) * | 2009-07-07 | 2013-08-14 | 清华大学 | 一种新的肿瘤标志物 |
CN103694332B (zh) * | 2009-07-07 | 2017-07-11 | 清华大学 | 一种新的肿瘤标志物 |
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US20140221240A1 (en) | 2014-08-07 |
EP2171453A1 (en) | 2010-04-07 |
CA2691980A1 (en) | 2009-01-08 |
US10605811B2 (en) | 2020-03-31 |
CA2691980C (en) | 2022-05-10 |
KR20120087885A (ko) | 2012-08-07 |
KR101262202B1 (ko) | 2013-05-16 |
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US20090004687A1 (en) | 2009-01-01 |
US20200256874A1 (en) | 2020-08-13 |
SG182976A1 (en) | 2012-08-30 |
JP2010532484A (ja) | 2010-10-07 |
US9846158B2 (en) | 2017-12-19 |
US9274118B2 (en) | 2016-03-01 |
WO2009006439A1 (en) | 2009-01-08 |
CN101855553B (zh) | 2014-06-11 |
EP2637020A3 (en) | 2014-01-08 |
KR20100062996A (ko) | 2010-06-10 |
EP2171453A4 (en) | 2010-10-06 |
US20160245818A1 (en) | 2016-08-25 |
MY150234A (en) | 2013-12-31 |
US20180074064A1 (en) | 2018-03-15 |
US8664358B2 (en) | 2014-03-04 |
BRPI0813002A2 (pt) | 2017-05-02 |
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