CN101816752A - Traditional Chinese medicament for preventing and treating avian influenza - Google Patents
Traditional Chinese medicament for preventing and treating avian influenza Download PDFInfo
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- CN101816752A CN101816752A CN200910064269A CN200910064269A CN101816752A CN 101816752 A CN101816752 A CN 101816752A CN 200910064269 A CN200910064269 A CN 200910064269A CN 200910064269 A CN200910064269 A CN 200910064269A CN 101816752 A CN101816752 A CN 101816752A
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Abstract
The invention discloses a traditional Chinese medicament for preventing and treating avian influenza, which is prepared from the following compositions: 12 to 18g of radix astragali, 12 to 16g of honeysuckle, 10 to 14g of weeping forsythiae capsule, 10 to 16g of wrinkled gianthyssop herb, 15 to 20g of large-headed atractylodes rhizome, 15 to 20g of fineleaf schizonepeta herb, 16 to 20g of divaricate saposhnikovia root, 18 to 25g of liquoric root, 15 to 20g of common lophatherum herb, 15 to 18g of platycodon root, 12 to 20g of bupleurum and 50 to 60g ofindigowoad root. The raw materials are selected; and the active ingredients are extracted and proportioned. A slow release/controlled release technique and a targeting medicament delivery technique are adopted, so that the medicament can effectively and quickly reach a lesion site and maintain the blood medicament concentration in an effective treatment range. Negative effects caused by quick incidence of the avian influenza, high fever and the like are effectively overcome.
Description
Technical field
The present invention relates to a few flavor Chinese medicines, especially relate to a kind of Chinese medicine of prophylactic treatment bird flu.
Background technology
Acute, deadly infectious disease that bird flu belongs to.Rapid onset, the mortality rate height, the form of bird flu prevention both at home and abroad and treatment is severe all the more.The medicine of the treatment bird flu of the tentative development of some company both at home and abroad is mostly in the pilot scale stage, and in using laying hen laid eggs and seriously influence.In addition, the Ministry of Agriculture has prohibited and has used Western medicine antiviral composition to be used for animal husbandry.Existing powder reaches the effective blood drug concentration length that takes time, and the course of treatment is long, and bird flu is not reached effective therapeutic effect.And it is little to the restitution of laying eggs after being ill.Thereby develop a kind of rapid-action, curative effect is high, to lay eggs the influence less Chinese medicine compeled to send at eyebrow.
Goal of the invention
Purpose of the present invention just be to provide a kind of rapid-action, curative effect is high, to the Chinese medicine of the less prophylactic treatment bird flu of influence of laying eggs.
Purpose of the present invention can realize by following measure:
The present invention is formed by following formulation, Radix Astragali 12-18g Flos Lonicerae 12-16g Fructus Forsythiae 10-14g Herba Pogostemonis 10-16g Rhizoma Atractylodis Macrocephalae 15-20g Herba Schizonepetae 15-20g Radix Saposhnikoviae 16-20g Radix Glycyrrhizae 18-25g Herba Lophatheri 15-20g Radix Platycodonis 15-18g Radix Bupleuri 12-20g Radix Isatidis 50-60g.
The present invention is formed by following formulation, Radix Scutellariae 16 grams, Flos Lonicerae 14 grams, Fructus Forsythiae 11 grams, Herba Pogostemonis 12 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Herba Schizonepetae 15 grams, Radix Saposhnikoviae 16 grams, Radix Glycyrrhizae 18 grams, Herba Lophatheri 15 grams, Radix Platycodonis 16 grams, Radix Bupleuri 14 grams, Radix Isatidis 53 grams.
Advantage of the present invention:
1, adopts controlled release and targeting technology, make medicine can directly arrive lesions position, and prolong effective time, strengthen the curative effect of Chinese herbal medicine.
2, adopt micronizing and cell wall breaking technology, the effective ingredient of medicine is played a role fast, adopt the critical monomer abstraction technique of carbon dioxide ultralow temperature simultaneously, effective ingredient is not destroyed and extracts fully, guarantee the effective ingredient abundance, drug effect increases.
3, ensure the core technology of product, guarantee product quality and curative effect.
4, adopt advanced finger print identification technology, the quality that guarantees selected Chinese crude drug is excellent level.
The present invention from raw-material screening, arrives the extraction of effective ingredient, proportioning owing to adopt above-mentioned prescription.And adopt release and target administration technology, make medicine can arrive lesions position effectively, rapidly, and keep blood drug level at an effective therapeutic domain.Effectively overcome the bird flu rapid onset, the negative effect that high thermal phenomenon etc. bring.Descend as feed intake; The follicle degeneration that hyperpyrexia causes recovers slower thereby lay eggs; Some inflammation that cause with secondary infection.Advantage of the present invention is specific as follows:
1, the drug effect performance is rapid, and treatment time is short, and side effect is little, and is easy to use
This Chinese herbal medicine is after micronizing, directly in water, can utilize and not stop up water fountain, prove according to clinical trial, observed in back 24 hours from dispensing, mine massively appetite and spirit of chicken takes an evident turn for the better, mortality rate descends to some extent after 48 hours, and feed intake recovers normal with spirit is basic after 22 hours, and the incidence rate of dissection back contrast yolk peritonitis is than the low 70-80% of matched group.As following table:
2, the longer duration that plays a role, lasting medicine
Through comparing: normal Chinese herbal medicine is 2-6 hour in the time that digestive system stops, and after micronizing and controlled-release technology processing, effective time at the birds digestive system is 6-10 hour, increased the time of staying in the intestinal greatly, absorption rate significantly increases, and through comparison, common Chinese (40-60 order) can detect a large amount of Chinese medicine prototypes after discharging with feces in intestinal, and this experiment product is after feces is discharged, and recall rate is no more than 10%.MIC also obviously differs simultaneously, and this experiment product is higher by 70% than common Chinese.
3, with strong points, the protective rate height
Throw this experiment product of clothes and throw the broiler of clothes common Chinese, after feeding four days, difference obviously occurs, as following table:
The specific embodiment
The present invention does with detailed description below in conjunction with drawings and Examples:
Embodiment 1
The present invention is formed by following formulation, Radix Astragali 12g Flos Lonicerae 12g Fructus Forsythiae 10g Herba Pogostemonis 10g Rhizoma Atractylodis Macrocephalae 15g Herba Schizonepetae 15g Radix Saposhnikoviae 16g Radix Glycyrrhizae 18g Herba Lophatheri 15g Radix Platycodonis 15g Radix Bupleuri 12g Radix Isatidis 50g.
The function of above-mentioned prescription:
Radix Isatidis: heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.
Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.
Flos Lonicerae: heat-clearing and toxic substances removing, heat radiation dispelling wind.
Fructus Forsythiae: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.
Herba Pogostemonis: removing dampness by means of aromatics and middle preventing or arresting vomiting, the diffusing pathogenic factor in the exterior of a surname, promoting qi circulation, resolving food retention.
The Rhizoma Atractylodis Macrocephalae: spleen reinforcing is good for the stomach, and the dampness diuretic is antiabortive, hidroschesis.
Herba Schizonepetae: deliver and dispel the wind, treating blood disorders, parch to black hemostasis.
Radix Saposhnikoviae: inducing diaphoresis to dispel wind, win and wet, spasmolytic.
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong.
Herba Lophatheri: heat clearing away, diuresis.
Radix Platycodonis: lung qi dispersing, eliminate the phlegm sore-throat relieving, evacuation of pus.
Radix Bupleuri: deliver and in, yang invigorating, soothing liver-QI.
Preparation technology of the present invention: at first select the quality raw materials micronizing according to above-mentioned prescription, the critical monomer abstraction technique of carbon dioxide ultralow temperature is adopted in the back, and effective ingredient is at utmost extracted.With the abundant mixing of extract, adopt controlled release and targeting technology to add controlled release agent, be prepared from.
Operation technique of the present invention
1, micronizing and cell wall technology: the grinding particle size of common Chinese herbal medicine is the 40-60 order, and the super granularity of pulverizing reaches more than 200 orders, in such cases, the cell wall of Chinese herbal medicine is destroyed, effective ingredient can be absorbed in the digestive system of birds fast, plays a role by blood circulation.
2, in basic research, adopt the critical monomer abstraction technique of carbon dioxide ultralow temperature, cryogenic temperature is (196 ℃), and the effective ingredient of medicine is not destroyed, and monomer extracts simultaneously, the main component that guarantees every kind of medicine is extracted into more than 90% and is not destroyed, and strengthens effective blood drug level.
3, controlled release and targeting technology; add special controlled release agent; what guarantee medicine continues, reaches fast blood drug level and bacteriocidal concentration; strengthen the absorption and the utilization of medicine, make the monomer effective ingredient have purpose to act on each organ simultaneously, remove virus fast; enhancing human body immunity power; alleviate clinical symptoms, protect unspoilt internal organs, reduce destruction fertility performance.
4, finger print identification technology under the effect of high power microscope (24 * 24), is utilized computer and detector, make medical material can fast detecting the place of origin, medical material classification, conformance with standard sample whether guarantees the quality of product.
Embodiment 2
The present invention is formed by following formulation, Radix Astragali 14g Flos Lonicerae 13g Fructus Forsythiae 11g Herba Pogostemonis 11g Rhizoma Atractylodis Macrocephalae 16g Herba Schizonepetae 16g Radix Saposhnikoviae 17g Radix Glycyrrhizae 19g Herba Lophatheri 16g Radix Platycodonis 16g Radix Bupleuri 14g Radix Isatidis 52g.
Other is with embodiment 1.
Embodiment 3
The present invention is formed by following formulation, Radix Astragali 15g Flos Lonicerae 14g Fructus Forsythiae 12g Herba Pogostemonis 12g Rhizoma Atractylodis Macrocephalae 17g Herba Schizonepetae 17g Radix Saposhnikoviae 18g Radix Glycyrrhizae 20g Herba Lophatheri 17g Radix Platycodonis 17g Radix Bupleuri 15g Radix Isatidis 55g.
Other is with embodiment 1.
Embodiment 4
The present invention is formed by following formulation, Radix Astragali 17g Flos Lonicerae 15g Fructus Forsythiae 13g Herba Pogostemonis 15g Rhizoma Atractylodis Macrocephalae 18g Herba Schizonepetae 19g Radix Saposhnikoviae 19g Radix Glycyrrhizae 23g Herba Lophatheri 19g Radix Platycodonis 17g Radix Bupleuri 19g Radix Isatidis 56g.
Other is with embodiment 1.
Embodiment 5
The present invention is formed by following formulation, Radix Astragali 18g Flos Lonicerae 16g Fructus Forsythiae 14g Herba Pogostemonis 16g Rhizoma Atractylodis Macrocephalae 20g Herba Schizonepetae 20g Radix Saposhnikoviae 20g Radix Glycyrrhizae 25g Herba Lophatheri 20g Radix Platycodonis 18g Radix Bupleuri 20g Radix Isatidis 60g.
Other is with embodiment 1.
Embodiment 6
The present invention is formed by following formulation, Radix Scutellariae 16 grams, Flos Lonicerae 14 grams, Fructus Forsythiae 11 grams, Herba Pogostemonis 12 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Herba Schizonepetae 15 grams, Radix Saposhnikoviae 16 grams, Radix Glycyrrhizae 18 grams, Herba Lophatheri 15 grams, Radix Platycodonis 16 grams, Radix Bupleuri 14 grams, Radix Isatidis 53 grams.
Other is with embodiment 1.
Claims (2)
1. the Chinese medicine of a prophylactic treatment bird flu, it is characterized in that: it is formed by following formulation, Radix Astragali 12-18g Flos Lonicerae 12-16g Fructus Forsythiae 10-14g Herba Pogostemonis 10-16g Rhizoma Atractylodis Macrocephalae 15-20g Herba Schizonepetae 15-20g Radix Saposhnikoviae 16-20g Radix Glycyrrhizae 18-25g Herba Lophatheri 15-20g Radix Platycodonis 15-18g Radix Bupleuri 12-20g Radix Isatidis 50-60g.
2. the Chinese medicine of prophylactic treatment bird flu according to claim 1 is characterized in that: the present invention is formed by following formulation, Radix Scutellariae 16 grams, Flos Lonicerae 14 grams, Fructus Forsythiae 11 grams, Herba Pogostemonis 12 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Herba Schizonepetae 15 grams, Radix Saposhnikoviae 16 grams, Radix Glycyrrhizae 18 grams, Herba Lophatheri 15 grams, Radix Platycodonis 16 grams, Radix Bupleuri 14 grams, Radix Isatidis 53 grams.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009100642695A CN101816752B (en) | 2009-02-26 | 2009-02-26 | Traditional Chinese medicament for preventing and treating avian influenza |
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| CN2009100642695A CN101816752B (en) | 2009-02-26 | 2009-02-26 | Traditional Chinese medicament for preventing and treating avian influenza |
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| CN101816752A true CN101816752A (en) | 2010-09-01 |
| CN101816752B CN101816752B (en) | 2011-08-31 |
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Cited By (16)
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| CN102225146A (en) * | 2011-05-30 | 2011-10-26 | 河南黑马动物药业有限公司 | Formula and production technology of traditional Chinese medicine injection for controlling bird flu |
| CN102430113A (en) * | 2011-12-16 | 2012-05-02 | 青岛绿曼生物工程有限公司 | Compound propolis composition for treating porcine pseudorabies and preparation method thereof |
| CN102488892A (en) * | 2011-12-28 | 2012-06-13 | 青岛绿曼生物工程有限公司 | Composite propolis composition used for treating unknown swine high-fever, and preparation method thereof |
| CN102526318A (en) * | 2011-12-09 | 2012-07-04 | 射洪郑葛生态养殖有限责任公司 | Chinese medicinal composition for preventing and treating chicken diseases and preparation method thereof |
| CN102600383A (en) * | 2012-02-09 | 2012-07-25 | 黑龙江省汇丰动物保健品有限公司 | Chinese medicinal herb preparation for poultry and application thereof |
| CN102671025A (en) * | 2012-05-24 | 2012-09-19 | 山东新希望六和集团有限公司 | Chinese herbal feed additive for preventing and treating avian influenza |
| CN103070972A (en) * | 2012-12-11 | 2013-05-01 | 河南省康星药业股份有限公司 | Normal temperature preparation method of Radix Scrophulariae and licorice submicron powder, and special bidirectional airflow screener therefor |
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| CN1879745B (en) * | 2006-05-16 | 2010-05-26 | 天津生机集团有限公司 | A veterinary Chinese medicinal powder for treating avian viral disease |
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2009
- 2009-02-26 CN CN2009100642695A patent/CN101816752B/en active Active
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| CN102225146A (en) * | 2011-05-30 | 2011-10-26 | 河南黑马动物药业有限公司 | Formula and production technology of traditional Chinese medicine injection for controlling bird flu |
| CN102526318A (en) * | 2011-12-09 | 2012-07-04 | 射洪郑葛生态养殖有限责任公司 | Chinese medicinal composition for preventing and treating chicken diseases and preparation method thereof |
| CN102430113B (en) * | 2011-12-16 | 2014-05-28 | 青岛绿曼生物工程有限公司 | Compound propolis composition for treating porcine pseudorabies and preparation method thereof |
| CN102430113A (en) * | 2011-12-16 | 2012-05-02 | 青岛绿曼生物工程有限公司 | Compound propolis composition for treating porcine pseudorabies and preparation method thereof |
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| CN102488892B (en) * | 2011-12-28 | 2014-03-19 | 青岛绿曼生物工程有限公司 | Composite propolis composition used for treating unknown swine high-fever, and preparation method thereof |
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| CN102600383B (en) * | 2012-02-09 | 2014-01-15 | 黑龙江省汇丰动物保健品有限公司 | Chinese medicinal herb preparation for poultry and application thereof |
| CN102671025A (en) * | 2012-05-24 | 2012-09-19 | 山东新希望六和集团有限公司 | Chinese herbal feed additive for preventing and treating avian influenza |
| CN103070972A (en) * | 2012-12-11 | 2013-05-01 | 河南省康星药业股份有限公司 | Normal temperature preparation method of Radix Scrophulariae and licorice submicron powder, and special bidirectional airflow screener therefor |
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| CN103585401A (en) * | 2013-03-26 | 2014-02-19 | 辽宁农业职业技术学院 | Traditional Chinese medicine composition for treating bird flu and preparation method therefor. |
| CN103933128A (en) * | 2014-04-30 | 2014-07-23 | 青岛农业大学 | Pharmaceutical composition for clearing away heat and toxic materials and preparation method thereof |
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| CN104586995A (en) * | 2014-06-26 | 2015-05-06 | 济南舜景医药科技有限公司 | Influenza preventing drug |
| CN104825780A (en) * | 2015-04-30 | 2015-08-12 | 新昌县大成生物科技有限公司 | Biological preparation for preventing chicken avian influenza |
| CN104840786A (en) * | 2015-05-14 | 2015-08-19 | 北京康华远景科技股份有限公司 | Medicine combination for preventing bird flu and preparation method thereof |
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| CN108295232A (en) * | 2018-04-10 | 2018-07-20 | 青岛农业大学 | A kind of Chinese medicine of prevention and treatment bird flu |
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