CN102600383B - Chinese medicinal herb preparation for poultry and application thereof - Google Patents
Chinese medicinal herb preparation for poultry and application thereof Download PDFInfo
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- CN102600383B CN102600383B CN201210028037.6A CN201210028037A CN102600383B CN 102600383 B CN102600383 B CN 102600383B CN 201210028037 A CN201210028037 A CN 201210028037A CN 102600383 B CN102600383 B CN 102600383B
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Abstract
The invention discloses a Chinese medicinal herb preparation for poultry. The effective constituents of a Chinese medicinal herb product disclosed by the invention are made up of echinacea purpurea, honeysuckle, hypericum perforatum, glycyrrhiza, folium isatidis, platycodon grandiflorum, lophatherum gracile, mint and hypericin. The Chinese medicinal herb preparation disclosed by the invention can relieve the exterior syndrome with drugs pungent in flavor and cool in property and clear away heat and toxic materials; and the main therapeutical effects include strengthening vital Qi and eliminating pathogens, balancing Yin and Yang, and improving non-specific immunity of organisms. The Chinese medicinal herb preparation for poultry has significant therapeutical effect for depressed spirit of poultry, feed intake decrease, egg laying reduction, eyelid swelling of poultry caused by unknown viruses, respiratory inflammation, yellow-green dung, weight increment decline, soft-shelled eggs, and death rate increment, etc.; furthermore, the Chinese medicinal herb preparation for poultry can be utilized to prevent the diseases of untypical Newcastle disease and avian influenza etc. and treat the relevant mixed infection, secondary infection, untypical diseases and chronic cases; and finally, the Chinese medicinal herb preparation for poultry well promotes the recovery of production performance after the poultry is healed.
Description
Technical field
The invention belongs to the poultry Chinese medicine preparation of a kind of nonspecific immunity ability for the righting of getting rid of evils, Yin Yang balancing, raising body in field of traditional Chinese veterinary.
Technical background
Along with improving constantly of livestock and poultry breeding industry scale, intensive degree, in livestock and poultry cultivation, various problems are also following.Especially aspect breeding layer chicken, occur the most serious.A variety of causes causes that laying hen egg yield declines, as infectious disease, nutrient deficiency, various stressors etc.The immunity of layer chicken that many reasons causes reduces and causes a great problem that egg production decline has become puzzlement raiser.At present, the method for main treatment various diseases and raising immunity of livestock is to take antibiotic and chemicals.In breeding process, also there is very large problem in the application of said medicine, and for guaranteeing livestock and poultry cultivation benefit, the abuse of medicine has also become the unavoidable fact.Along with China's sustained economic development and name living standard improve, animal food proportion in people's diet structure is increasing.And the abuse of said medicine is when being with meter economic benefit for raiser, also for food safety brings hidden trouble.Chinese herbal medicine is little as a kind of toxic and side effects, lasting medicine, the environmental protection product that be difficult for to produce drug resistance and versatility can either improve immunity of livestock, ensures raiser's economic benefit, can not bring again the potential safety hazard of Drug abuse, has a wide range of applications.
Accompanying drawing explanation
Fig. 1: viewing duration is respectively organized chicken feed intake and changed (g/ only)
Fig. 2: viewing duration is respectively organized laying rate of chicken and changed (%)
Fig. 3: extracorporeal bacteria inhibitor test result is for No. 3 wherein antibiotic contrast; Being for No. 2 sense Sha A contrast, is for No. 1 Lonicerae and Forsythiae Powder matched group.
Summary of the invention
The object of the invention is to the problem and shortage for current existence, a kind of compound Chinese herb is provided, improve immunity of livestock, particularly laying rate of laying hen.
Product sense Sha A of Chinese herbal medicine of the present invention is comprised of Echinacea, Flos Lonicerae, Herba Hyperici perforati, Radix Glycyrrhizae, Folium Isatidis, Radix Platycodonis, Herba Lophatheri, Herba Menthae and hypericin.Chinese herbal medicine of the present invention can relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, heat-clearing and toxic substances removing; Cure mainly: the righting of getting rid of evils, Yin Yang balancing, the nonspecific immunity ability of raising body.Chinese herbal medicine of the present invention is depressed to the spirit of poultry, and feed intake reduces, egg drop reduction, and the poultry eyelid swelled that causes of not clear virus, and respiratory inflammation, yellow green feces, weightening finish declines, and produces soft-shelled egg, and mortality rate rising etc. all has significant therapeutic effect; Can be used in atypical newcastle disease, the early prevention and treatment that bird flu etc. are sick and to relevant mixed infection, secondary infection, the treatment of the sick and chronic case of atypia; Rear fertility performance is recovered also to have good facilitation.
Chinese herbal medicine product sense Sha A of the present invention can be powder, powder, oral liquid, tablet, pill, capsule, unguentum.
Sense Sha A of the present invention, except described active constituents of medicine, also comprises pharmaceutically acceptable adjuvant.Specifically consisting of of Chinese herbal and crude drugs preparations sense Sha's A active ingredient of the present invention:
The instructions of taking of sense Sha A: feel A100 gram of Sha and be watered 100 kilograms, whole day is drunk, and is used in conjunction 3-5 days.
The specific embodiment
Embodiment 1: the therapeutic test of sense Sha A to naturally-occurring chicken colibacillosis and virosis
9100 sick chickens, clinical symptoms: morbidity chicken occurs that spirit is depressed, cockscomb, whisker are blue, rubescent, feather pine disorderly, tarnish, the necking down of hanging one's head, wing is sagging, eye semi-closure or full cut-off are like lethargic state.Feed intake declines and has obvious dyspnea symptom, with " snore " sound, and cough, secretions increase in oral cavity.Produce thin skin, Rhizoma Euonymus egg, row's yellow-white or yellow green loose stool.Diagnosis: the mixed sense of virosis and colibacillosis.Observe in contrast with 100, be left intact, all the other 9000 chickens are divided into 3 groups, and 3000 every group, first group with antibiotic therapy, add the ofloxacin 03g+ amantadine 0.1g+ medicine that induces sweat, mixed drink, continuously 5d in every 1L drinking-water; With Lonicerae and Forsythiae Powder, treat for second group, in every 1L drinking-water, add powder 2g, mixed drink, continuously 5d; Use sense Sha A for the 3rd group, 100g is watered 100kg, is used in conjunction 5 days.
Chicken group clinical symptoms change and death condition:
Antibiotic, Lonicerae and Forsythiae Powder and sense Sha's A treatment group spirit from the 2nd day are faded in vivaciously, and activity constantly increases; From the 3rd day, drink, appetite were recovered normally gradually, and abnormal stool reduces day by day so that disappears; From treating soft-shelled egg the 3rd day, husky preserved egg and damaged egg, reduce gradually laying rate bottom out; From treating death the 4th day, stop, until observe, finishing, chicken group is always healthy and stable, then does not have new case to occur.
Table 1 viewing duration is respectively organized chicken death situation (unit: plumage)
Note:
※compare with matched group, significant difference (P < 0.05=,
※ ※compare with matched group, difference extremely significantly (P < 0.01=, lower with.Feed intake changes:
As shown in Figure 1, than matched group, antibiotic, Lonicerae and Forsythiae Powder and sense Sha A treatment group feed intake are recovered gradually, and tend towards stability after the 5th day, and sense Sha A treatment group effect is slightly better than other two groups.
Laying rate changes:
As shown in Figure 2, than matched group, antibiotic, Lonicerae and Forsythiae Powder and sense Sha A treatment group egg production improve by sky, and sense Sha A treatment group therapeutic effect is slightly better than other two groups.
Embodiment 2: In Vitro Bacteriostasis experiment
1. test material:
1.1 culture medium: do colibacillary drug sensitive test and select ordinary nutrient agar or the triumphant culture medium of wheat bran
1.2 drug susceptability test papers: self-control.
1.3 antibacterials: the escherichia coli of drug sensitive test.
1.4 inoculating loops, alcohol burner, card punch, Oxford cup.
1.5 pipettors, water dropper.
2. test is prepared:
The preparation of 2.1 susceptibility sheets: get No. 1 qualitative filter paper of Xinhua, break into the little scraps of paper of circle of 6 mm dias with puncher.Get 50, the round scraps of paper and put into clean dry penicillin empty bottle, bottleneck is wrapped up with monolayer kraft paper.After 15 pounds of high pressure, 15-20 minute sterilization, be placed on a couple of days in 37 ℃ of incubators or baking oven, make bone dry.
The 2.2 antimicrobial drug scraps of paper are made: in the above-mentioned penicillin bottle that contains 50 scraps of paper, add 0.25 milliliter of medicinal liquid, and stir the scraps of paper, make each scraps of paper fully soak into medicinal liquid, while stirring the scraps of paper, the scraps of paper can not be mashed.Simultaneously on bottleneck, recording medicine name, put in 37 ℃ of incubators and spend the night, is Mi Gai after dry, as have ready conditions can vacuum drying.Keep Dry, puts dark dry place and deposit, effect duration 3-6 month.
The preparation of 2.3 medicinal liquids (for the test of commercially available medicine): the ratio preparating liquid that uses therapeutic dose in commercially available medicine; If commercially available medicine " all kinds of diseases and ailments disappear " is by its explanation amount therapeutic dose 0.01% drinking-water, can be in this ratio preparating liquid, desirable 10 milligrams add in the water of 10 milliliters and mix.This diluent is for doing the medicinal liquid of drug sensitive test.
3. experimental working technique:
(1) bacterium sample is inoculated in to the triumphant culture medium flat plate of wheat bran, cultivates 16～18 hours for 37 ℃, then the pure culture bacterium colony on the triumphant culture medium flat plate of picking wheat bran, is suspended from 3ml normal saline, after mixing with bacterium liquid opacity tube than turbid.Take and have the blank sheet of paper of surplus as background, adjust turbidity identical with opacity tube (0.5 Maxwell unit).
(2) with sterile cotton swab, dip bacterium liquid, on tube wall, unnecessary bacterium liquid is removed in extruding.With cotton swab, be coated with the triumphant media surface of whole wheat bran, repeatedly several times, at every turn by flat board rotation 60 degree, tailing edge periphery, around Liang Quan, guarantees to be coated with evenly.
(3) paster sheet again after the moisture on flat board is absorbed completely by agar.With aseptic nipper, get drug sensitive test paper and be attached to planar surface, the scraps of paper can not be picked up once pasting again.5 scraps of paper of each dull and stereotyped subsides, every scraps of paper spacing is no less than 24mm, and scraps of paper centre-to-centre spacing plate edge is no less than 15mm.Tweezers are slightly stopped after alcohol burner flame sterilization, get it filled quick and be attached to plate media surface.For susceptibility sheet and culture medium are closely affixed, several lower susceptibility sheets of available tweezers flicking.For making can accurately observed result, require the susceptibility sheet can regular being distributed in plate culture medium; Generally can paste a slice in plate central authorities, periphery can some of equidistant subsides (periphery generally can be pasted seven), and the title of every kind of susceptibility sheet will be remembered.Bacterium, inoculate in latter 15 minutes and pasted the scraps of paper.
(4) by flat board reversion, hatch after 18～24 hours and take out, use vernier caliper measurement antibacterial circle diameter, from the dull and stereotyped back side, measure immediate integer millimeter record.
4. In Vitro Bacteriostasis experimental result as shown in Figure 3, is for No. 3 wherein antibiotic contrast; Being for No. 2 sense Sha A contrast, is for No. 1 Lonicerae and Forsythiae Powder matched group.As shown in Figure 3, sense Sha A and matched group demonstration, have obvious therapeutic effect, and with the comparison of antibiotic group, difference is not remarkable.
Claims (3)
1. Chinese herbal and crude drugs preparations sense Sha A, is characterized in that: the active ingredient of said preparation is comprised of Echinacea, Flos Lonicerae, Herba Hyperici perforati, Radix Glycyrrhizae, Folium Isatidis, Radix Platycodonis, Herba Lophatheri, Herba Menthae and hypericin, shown in its concrete active ingredient is composed as follows:
2. Chinese herbal and crude drugs preparations sense Sha A as claimed in claim 1, is characterized in that described preparation is powder, powder, oral liquid, tablet, pill, capsule, unguentum.
3. Chinese herbal and crude drugs preparations sense Sha A as claimed in claim 1 or 2, is characterized in that described preparation also comprises pharmaceutically acceptable adjuvant.
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102813061B (en) * | 2012-09-11 | 2018-06-15 | 北京大北农科技集团股份有限公司 | One hatching egg fowl plant feed addictive, premix and batch |
| CN103655999B (en) * | 2013-12-29 | 2015-10-21 | 衡阳市金凤牲猪养殖专业合作社 | Medicine of control bird flu and preparation method thereof |
| CN103976149B (en) * | 2014-04-28 | 2015-09-30 | 彭鸿贰 | A kind of Chinese herbal feed additive of birds flu-preventing |
| CN104186969A (en) * | 2014-07-29 | 2014-12-10 | 合肥德邦动物保健有限公司 | Preparation method of chicken feed additive containing chitosan |
| CN104524016B (en) * | 2014-12-16 | 2018-08-14 | 河北科技师范学院 | Prevent the herbal composite that chicken viral laying rate declines |
| CN105232763A (en) * | 2015-10-19 | 2016-01-13 | 中国农业科学院兰州畜牧与兽药研究所 | Traditional Chinese medicine combination for treating avian respiratory tract infection and preparation method and application thereof |
| CN105935104A (en) * | 2016-04-25 | 2016-09-14 | 大新县生产力促进中心 | Pure natural poultry feed additive and preparation method thereof |
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| CN101390920A (en) * | 2007-09-21 | 2009-03-25 | 天津生机集团有限公司 | Traditional Chinese medicine for livestock and poultry and preparation method thereof |
| CN101816752A (en) * | 2009-02-26 | 2010-09-01 | 河南天纳图生物科技有限公司 | Traditional Chinese medicament for preventing and treating avian influenza |
| CN102166255A (en) * | 2011-03-02 | 2011-08-31 | 华南农业大学 | Chinese medicinal composition for increasing chicken production performance |
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- 2012-02-09 CN CN201210028037.6A patent/CN102600383B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1788779A (en) * | 2004-12-16 | 2006-06-21 | 高健 | Body-strengthening conditioning agent for fowl and livestock |
| CN101390920A (en) * | 2007-09-21 | 2009-03-25 | 天津生机集团有限公司 | Traditional Chinese medicine for livestock and poultry and preparation method thereof |
| CN101152340A (en) * | 2007-09-30 | 2008-04-02 | 江苏畜牧兽医职业技术学院 | Traditional Chinese medicine composition for birds, preparing method and application of the same |
| CN101352486A (en) * | 2008-08-15 | 2009-01-28 | 天津生机集团股份有限公司 | Isatis root and astragalus microspheres for injections and preparation method thereof |
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| CN102166255A (en) * | 2011-03-02 | 2011-08-31 | 华南农业大学 | Chinese medicinal composition for increasing chicken production performance |
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Address after: 151100 Zhaodong Economic Development Zone, Heilongjiang Applicant after: Heilongjiang Huifeng Animal Health Products Co., Ltd. Applicant after: Qingdao Huifeng Animal Health-Care Products Co., Ltd. Address before: 151100 Zhaodong Economic Development Zone, Heilongjiang Applicant before: Heilongjiang Huifeng Animal Health Products Co., Ltd. Applicant before: Qingdao Kyaha Animal Pharmaceutical Co., Ltd. |
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