CN101658551A - Honeysuckle composition for resisting virus diseases of pigs - Google Patents
Honeysuckle composition for resisting virus diseases of pigs Download PDFInfo
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- CN101658551A CN101658551A CN200810141133A CN200810141133A CN101658551A CN 101658551 A CN101658551 A CN 101658551A CN 200810141133 A CN200810141133 A CN 200810141133A CN 200810141133 A CN200810141133 A CN 200810141133A CN 101658551 A CN101658551 A CN 101658551A
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Abstract
The invention discloses a honeysuckle composition for resisting virus diseases of pigs, and relates to a feed additive or Chinese veterinary medicine special for preventing and controlling the virus diseases of the pigs and capable of promoting the growth of the pigs. The composition consists of the following components: 30 to 60 portions of honeysuckle extract, 5 to 20 portions of Chinese thorowax root extract, 5 to 20 portions of baical skullcap root P.E, 5 to 20 portions of dandelion P.E, and 10 to 25 portions of licorice extract. The composition is Chinese medicinal powder of which the granularity is between 200 and 300 meshes and which is yellow or brown-yellow, and has the following content of the active components: 5 to 20 percent of chlorogenic acid, 2 to 10 percent of baicalin and5 to 15 percent of glycyrrhizic acid. When used, the composition is mixed with a feed in a ratio of 0.02-0.2 percent and then is fed to animals. The composition has the effect of preventing and controlling highly pathogenic blue ear pig disease, porcine rotavirus disease, influenza, infectious bronchitis and the like, and virus diseases caused by porcine circovirus PCV, foot-and-mouth disease virus and the like, and can effectively promote the growth of the live pigs.
Description
Technical field
The present invention relates to a kind of being exclusively used in and prevent and the treatment virus diseases of pigs, and can promote the honeysuckle composition of pig growth, can be used as herbal medicine or feed additive.
Background technology
The pig-breeding industry always is the emphasis of animal husbandry, is rapidly developed in recent years.For a long time, hinder live pig already to develop and the subject matter that influences pig industry is the threat of described virus diseases of pigs.The swine diseases virus big to the live pig threat mainly contains: the pig breeding is maximum with breathing syndrome (high-pathogenicity blue ear disease) harm with the serious type pig breeding that breathing syndrome virus (PRRSV), porcine circovirus 2 type (PCV2), swine fever virus (CSFV), swine influenza virus (SIV), porcine pseudorabies virus (PRV), particularly PRRSV cause.This disease sickness rate and case fatality rate height, swinery sickness rate 50%-100%, case fatality rate 20%-100%, since 2006, the outburst of high-pathogenicity blue ear disease and popular is that China's pig industry has stood once beyond example strike, loses huge.
At present, the control of above-mentioned virus diseases of pigs is mainly relied on vaccination prevention, antiviral treatment and reinforcement sterilization management, these methods the control epidemic isolates infect and the effect of morbidity not very good, the control of virus diseases of pigs remains world-famous puzzle.At first, the swine diseases virus variation is big, same pig farm has different viral subgroups, easily develop immunity to drugs, up to now, still do not have specific chemotherapeutic agent, and the chemical classes medicine not only has limitation aspect the viral disease preventing and treating, also can in animal products, form a large amount of drug residues, the human long-term edible diseases such as canceration, deformity that easily cause.Vaccine effect is imprecise, and can cause stress, make to cause morbidity after being with malicious swinery vaccination.Secondly, along with the development of live pig large-scale cultivation, immunity of pig and premunition descend, and the transaction circulation is accelerated, and makes virus diseases of pigs become more complicated, usually shows as multiple virus mixed infection, cause difficulty of prevention and cure to strengthen, in case popular, very harmful.
Modern pharmacology is discovered, Chinese medicines such as Flos Lonicerae have good antivirus action, both can directly kill virus and not injure body tissue, can transfer the enthusiasm of immune defense system again, the active immunity mechanism of excitating organism, enhancing immunity is by initiatively defending performance antivirus action indirectly.Especially in face of this global problem of virus diseases of pigs, the superiority of Chinese medicine is more outstanding.Many Chinese medicine antiviral activity compositions, as direct kill virus not only such as flavonoid, polysaccharide and derivant thereof, triterpenoid compound and derivant thereof (as the glycyrrhizin derivant), alkaloid, glycoside, can also stop virus to the absorption of host cell with penetrate, suppressing virus duplicates in host cell, blocking virus from infection cell to the infecting of non-infected cells, thereby play direct antivirus action.The more important thing is that many Chinese medicines can also enhancing human body immunity power, excites the animal body immune defense system, has indirect antivirus action, can improve anti-stress ability simultaneously, promote the live pig growth.
Chinese medicine commonly used such as Flos Lonicerae, Radix Bupleuri, Radix Scutellariae, Rhizoma Polygonati, the Radix Astragali, Radix Trichosanthis, Radix Glycyrrhizae, Fructus Schisandrae Chinensis, Herba Epimedii, Spica Prunellae, Radix Sophorae Flavescentis, Semen Lablab Album, Herba Schizonepetae, Cortex Moutan, the Radix Paeoniae Alba, Rhizoma Cimicifugae, Folium Perillae etc. all have immunoloregulation function, can bring into play antivirus action by immunomodulating.Chinese medicines such as Caulis Lonicerae, Radix Sophorae Tonkinensis, Herba Artemisiae Annuae, Radix Paeoniae Rubra, Herba Taxilli, Rhizoma Osmundae all have inhibitory action to virus, possess the effect of opposing viral infection.Better with the compound preparation that Chinese medicine antiviral effective ingredient is formed than folk prescription effect.
Summary of the invention
The present invention is in order to overcome weak point of the prior art, according to virus diseases of pigs pathogeny and pig growth physiological property, selection has the biological active substances of anti virus herb extract, form compound preparation, provide a kind of and can effectively prevent and treat virus diseases of pigs, promote growth, and noresidue in the live pig body, the honeysuckle composition of the resisting virus diseases of pigs that does not develop immunity to drugs.
The Chinese herbal medicine that the present invention adopts is high-quality Flos Lonicerae, Radix Bupleuri, Radix Scutellariae, Herba Taraxaci and Radix Glycyrrhizae, and its ratio comprises: Flos Lonicerae extract 30-60% is preferably 35-45%; Radix Bupleuri extract 5-20% is preferably 10-15%; Radix Scutellariae extract 5-20% is preferably 10-15%; Herba Taraxaci extract 5-20% is preferably 10-15%; Radix Glycyrrhizae extract 10-25 is preferably 15-20% part formation.
The above-mentioned Chinese medicine extract that the present invention adopts is according to its effective constitutive property separately, through extract, concentrate, refining, drying forms, in order to reduce loss of active ingredients in the dry run, dry vacuum drying or the spray drying of adopting.When extract is produced, can be that every kind of medical material extracts separately, also can be to extract simultaneously after several medical materials are mixed in proportion, be preferably independent extraction after, press the extract mixed.
The honeysuckle composition of the resisting virus diseases of pigs of the present invention's preparation, outward appearance are extremely pale brown toner end of 200-300 icteric sclera color, have distinctive Chinese medicine fragrance, active constituent content: chlorogenic acid 5-20%, baicalin 2-10%, glycyrrhizic acid 5-15%.
The honeysuckle composition of the resisting virus diseases of pigs of the present invention's preparation, adding proportion in feedstuff is 0.02-0.2%, have high reproductive and respiratory syndrome, porcine rotavirus disease, influenza, the infectious bronchitis etc. of causing a disease of prevention and treatment pig, and the viral disease that causes by pig circular ring virus, little Orbivirus, foot and mouth disease virus etc., and can effectively promote the growth of live pig.
The specific embodiment
Embodiment one
A kind of honeysuckle composition of resisting virus diseases of pigs
Prescription:
Flos Lonicerae extract (chlorogenic acid content: 20%): 400g
Radix Scutellariae extract (content of baicalin: 40%): 150g
Radix Bupleuri extract: 150g
Herba Taraxaci extract: 150g
Radix Glycyrrhizae extract (glycyrrhizic acid: 150g 40%)
The said extracted thing is mixed packing, packaging of aluminium foil bag, every bag of 500g.Be used for high reproductive and respiratory syndrome, porcine rotavirus disease, influenza, the infectious bronchitis etc. of causing a disease of prevention and treatment pig, and the viral disease that causes by pig circular ring virus, little Orbivirus, foot and mouth disease virus etc.In feedstuff, add during prevention, in feedstuff, add during treatment in 0.1% ratio in 0.05% ratio.
Embodiment two
A kind of honeysuckle composition of resisting virus diseases of pigs
Prescription:
Flos Lonicerae 3500g, Radix Scutellariae 1500g, Radix Bupleuri 2000g, Herba Taraxaci 2000g, Radix Glycyrrhizae 1500g.
Take by weighing the Chinese medicine of respectively distinguishing the flavor of, Radix Scutellariae by above-mentioned recipe quantity, the Radix Glycyrrhizae section, water decocts three times, 2 hours for the first time, second, three times each 1 hour, collecting decoction, filter, being concentrated into relative density is the extractum of 1.20～1.30 (70～80 ℃ of surveys), when being chilled to 40 ℃, stir and slowly add ethanol down, make the alcohol amount of containing reach 60%-70%, fully stir, left standstill 24 hours, the leaching supernatant, it is an amount of that residue adds 75% ethanol, left standstill 12 hours, filters, merge ethanol liquid, reclaim ethanol and do not distinguish the flavor of, and be condensed into the extractum that relative density is 1.10～1.30 (60～70 ℃ of surveys), spray drying to there being alcohol, obtain Flos Lonicerae combined extracts 1000g, press embodiment one method and use.
Claims (4)
1, a kind of honeysuckle composition of resisting virus diseases of pigs is characterized in that said composition is made of Flos Lonicerae extract 30-60 part, Radix Bupleuri extract 5-20 part, Radix Scutellariae extract 5-20 part, Herba Taraxaci extract 5-20 part, Radix Glycyrrhizae extract 10-25 part.
2, the honeysuckle composition of resisting virus diseases of pigs according to claim 1 is characterized in that described compositions is above-mentioned Chinese medicine through fully mixing after effective component extracting, the drying respectively, or after the mixed extraction, refining, concentrate, drying forms.
3, the honeysuckle composition of resisting virus diseases of pigs according to claim 1 is characterized in that described compositions is that granularity is extremely pale brown toner end of 200-300 icteric sclera color, active constituent content: chlorogenic acid 5-20%, baicalin 2-10%, glycyrrhizic acid 5-15%.
4, the honeysuckle composition of resisting virus diseases of pigs according to claim 1, it is characterized in that described compositions is 0.02-0.2% for the adding proportion in feedstuff, have high reproductive and respiratory syndrome, porcine rotavirus disease, influenza, the infectious bronchitis etc. of causing a disease of prevention and treatment pig, and the viral disease that causes by pig circular ring virus, little Orbivirus, foot and mouth disease virus etc., and can effectively promote the growth of live pig.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200810141133A CN101658551A (en) | 2008-08-27 | 2008-08-27 | Honeysuckle composition for resisting virus diseases of pigs |
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| CN200810141133A CN101658551A (en) | 2008-08-27 | 2008-08-27 | Honeysuckle composition for resisting virus diseases of pigs |
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Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102370970A (en) * | 2011-10-12 | 2012-03-14 | 青岛绿曼生物工程有限公司 | Traditional Chinese medicine compound composition for treating blue ear disease of sows and preparation method thereof |
| CN102579622A (en) * | 2012-03-03 | 2012-07-18 | 贵州省畜牧兽医研究所 | Chinese herbal preparation for treating haemophilusparasuis and preparation method thereof |
| CN102698193A (en) * | 2012-05-31 | 2012-10-03 | 四川金瑞克动物药业有限公司 | Chinese medicinal injection for preventing and controlling pig exogenous febrile diseases and preparation method thereof |
| CN102846866A (en) * | 2012-08-28 | 2013-01-02 | 郑州后羿制药有限公司 | Chinese medicine composition for prevention and control of porcine circovirus disease and preparation method thereof |
| CN103458702A (en) * | 2011-10-07 | 2013-12-18 | 韩国韩医学研究院 | Composition for use in liquid feed or as feed additive |
| CN103599414A (en) * | 2013-11-12 | 2014-02-26 | 青岛绿曼生物工程有限公司 | Traditional Chinese medicine composition for treating porcine pseudorabies and preparation method thereof |
| CN104225182A (en) * | 2014-08-23 | 2014-12-24 | 施瑞客（天津）生物技术有限公司 | Traditional Chinese medicine oral liquid for treating swine pox and preparation method thereof |
| CN106265945A (en) * | 2016-09-21 | 2017-01-04 | 西安乐道生物科技有限公司 | A kind of SHUANGHUANLIAN effervescent granule for animals and preparation method thereof |
| CN106615858A (en) * | 2017-02-09 | 2017-05-10 | 安徽菲扬农业科技有限公司 | Feed used for preventing porcine foot-and-mouth disease |
| CN107158087A (en) * | 2017-05-31 | 2017-09-15 | 贵州省铜仁市万山区京军生态农牧发展有限公司 | It is a kind of to prevent Chinese medicine composition of hog cholera and preparation method thereof |
| CN107223628A (en) * | 2017-05-09 | 2017-10-03 | 安徽禾泉农庄生态农业有限公司 | A kind of cultural method for preventing and treating wild boar Schweineseuche disease |
| CN108743836A (en) * | 2018-08-27 | 2018-11-06 | 维康腾达生物科技有限公司 | A kind of anti virus herb composition and preparation method thereof |
| CN110679767A (en) * | 2019-11-21 | 2020-01-14 | 何祥 | Mixed pig feed additive and preparation method thereof |
| CN113662993A (en) * | 2021-10-11 | 2021-11-19 | 苏州科牧生物技术有限公司 | Antiviral veterinary drug and preparation method thereof |
-
2008
- 2008-08-27 CN CN200810141133A patent/CN101658551A/en active Pending
Cited By (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103458702A (en) * | 2011-10-07 | 2013-12-18 | 韩国韩医学研究院 | Composition for use in liquid feed or as feed additive |
| CN102370970B (en) * | 2011-10-12 | 2014-05-07 | 青岛绿曼生物工程有限公司 | Traditional Chinese medicine compound composition for treating blue ear disease of sows and preparation method thereof |
| CN102370970A (en) * | 2011-10-12 | 2012-03-14 | 青岛绿曼生物工程有限公司 | Traditional Chinese medicine compound composition for treating blue ear disease of sows and preparation method thereof |
| CN102579622A (en) * | 2012-03-03 | 2012-07-18 | 贵州省畜牧兽医研究所 | Chinese herbal preparation for treating haemophilusparasuis and preparation method thereof |
| CN102698193A (en) * | 2012-05-31 | 2012-10-03 | 四川金瑞克动物药业有限公司 | Chinese medicinal injection for preventing and controlling pig exogenous febrile diseases and preparation method thereof |
| CN102846866A (en) * | 2012-08-28 | 2013-01-02 | 郑州后羿制药有限公司 | Chinese medicine composition for prevention and control of porcine circovirus disease and preparation method thereof |
| CN102846866B (en) * | 2012-08-28 | 2014-09-24 | 郑州后羿制药有限公司 | Chinese medicine composition for prevention and control of porcine circovirus disease and preparation method thereof |
| CN103599414B (en) * | 2013-11-12 | 2016-08-10 | 青岛众志合才智能科技有限公司 | Chinese medicine composition for the treatment of porcine pseudorabies and preparation method thereof |
| CN103599414A (en) * | 2013-11-12 | 2014-02-26 | 青岛绿曼生物工程有限公司 | Traditional Chinese medicine composition for treating porcine pseudorabies and preparation method thereof |
| CN104225182A (en) * | 2014-08-23 | 2014-12-24 | 施瑞客（天津）生物技术有限公司 | Traditional Chinese medicine oral liquid for treating swine pox and preparation method thereof |
| CN106265945A (en) * | 2016-09-21 | 2017-01-04 | 西安乐道生物科技有限公司 | A kind of SHUANGHUANLIAN effervescent granule for animals and preparation method thereof |
| CN106615858A (en) * | 2017-02-09 | 2017-05-10 | 安徽菲扬农业科技有限公司 | Feed used for preventing porcine foot-and-mouth disease |
| CN107223628A (en) * | 2017-05-09 | 2017-10-03 | 安徽禾泉农庄生态农业有限公司 | A kind of cultural method for preventing and treating wild boar Schweineseuche disease |
| CN107158087A (en) * | 2017-05-31 | 2017-09-15 | 贵州省铜仁市万山区京军生态农牧发展有限公司 | It is a kind of to prevent Chinese medicine composition of hog cholera and preparation method thereof |
| CN108743836A (en) * | 2018-08-27 | 2018-11-06 | 维康腾达生物科技有限公司 | A kind of anti virus herb composition and preparation method thereof |
| CN110679767A (en) * | 2019-11-21 | 2020-01-14 | 何祥 | Mixed pig feed additive and preparation method thereof |
| CN113662993A (en) * | 2021-10-11 | 2021-11-19 | 苏州科牧生物技术有限公司 | Antiviral veterinary drug and preparation method thereof |
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Application publication date: 20100303 |