CN108743836A - A kind of anti virus herb composition and preparation method thereof - Google Patents

A kind of anti virus herb composition and preparation method thereof Download PDF

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Publication number
CN108743836A
CN108743836A CN201810982833.0A CN201810982833A CN108743836A CN 108743836 A CN108743836 A CN 108743836A CN 201810982833 A CN201810982833 A CN 201810982833A CN 108743836 A CN108743836 A CN 108743836A
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campanulaceae
dandelion
grass
raw material
weight
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周维辉
李桂莲
文欣伟
胡素纺
刘瑞莹
邵东方
张召阳
祝东诚
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Wei Kang Tengda Biotechnology Co Ltd
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Wei Kang Tengda Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P31/14Antivirals for RNA viruses
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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    • A61K2236/50Methods involving additional extraction steps
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The present invention relates to a kind of anti virus herb compositions and preparation method thereof, it is made of the raw material of following parts by weight:Dandelion 1-5, sweet wormwood 5-15, reed root 5-12, campanulaceae 8-20, radix scutellariae 60-80, radix bupleuri 10-15 and grass-leaved sweetflag 5-10;Specific preparation method is that each raw material is weighed mixing according to proportioning, crushing water logging, rotary evaporation, and last drying and crushing obtains finished product;The Chinese medicine composition has effects that clearing heat and detoxicating, analgesia, diffusing lung, relieving exterior syndrome, invigorating the spleen tonifying Qi, adjusts body immunity.

Description

A kind of anti virus herb composition and preparation method thereof
Technical field
The invention belongs to pharmaceutical technology fields, and in particular to a kind of anti virus herb composition and preparation method thereof.
Background technology
In recent years, death caused by more and more virus infection has been reported, such as SARS (serious acute respiratory systems Unite syndrome), norovirus (norovirus) and bird flu.Due to increasingly flourishing transportation network and the disease constantly to make a variation Poison, a wide range of popular foreground cause global threat now.The appearance of new influenza virus and needs are acted immediately urgent Problem.Although exploitation antiviral vaccine is a solution of these problems and currently peremptorily carries out, by In the specificity of vaccine, they are only effective in terms of the infection for inhibiting specific virus.Because production of vaccine is that needs are quite a lot of The process of time, so being generally difficult to the specific vaccine of deposit demand.Thus, it is this for the various equal tables of virus The demand for revealing the antivirotic of antiviral activity is very vigorous.
Invention content
For overcome the deficiencies in the prior art, a kind of anti virus herb composition of present invention proposition and preparation method thereof, should Chinese medicine composition has effects that clearing heat and detoxicating, analgesia, diffusing lung, relieving exterior syndrome, invigorating the spleen tonifying Qi, adjusts body immunity.
The purpose of the present invention is what is realized in the following manner:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 1-5, sweet wormwood 5-15, reed root 5-12, campanulaceae 8-20, radix scutellariae 60-80, radix bupleuri 10-15 and grass-leaved sweetflag 5-10.
According to above-mentioned anti virus herb composition, it is made of the raw material of following parts by weight:Dandelion 1-3, sweet wormwood 10- 15, reed root 5-8, campanulaceae 15-20, radix scutellariae 60-70, radix bupleuri 13-15 and grass-leaved sweetflag 5-8.
According to above-mentioned anti virus herb composition, it is made of the raw material of following parts by weight:Dandelion 3-5, sweet wormwood 5- 10, reed root 8-12, campanulaceae 8-15, radix scutellariae 70-80, radix bupleuri 10-13 and grass-leaved sweetflag 8-10.
According to above-mentioned anti virus herb composition, it is made of the raw material of following parts by weight:Dandelion 3, sweet wormwood 12, reed Root 8, campanulaceae 16, radix scutellariae 72, radix bupleuri 12 and grass-leaved sweetflag 6.
According to the preparation method of above-mentioned anti virus herb composition, it includes the following steps:
(1)Weigh above-mentioned raw materials dandelion, sweet wormwood, reed root, campanulaceae, radix scutellariae, radix bupleuri and grass-leaved sweetflag, it is spare after decontamination;
(2)The above-mentioned raw materials medicine mixing of the parts by weight is added to being ground into 200-300 mesh powder in micronizer, The drug of crushing is soaked in water 40-60 minutes;(3)By soaked drug be put into microwave abstracting machine 400-600w power Lower microwave 4-8 minutes is then placed in Rotary Evaporators drying 20 minutes under the conditions of 70-85 DEG C, and it is finished product finally to crush.
In the present invention the effect of each bulk pharmaceutical chemicals:
Dandelion:Nature and flavor are sweet, slight bitter, tremble with fear.Return liver, stomach.Contain taraxol, taraxacin, choline, organic in plant A variety of health-nutrition ingredients such as acid, synanthrin.There are diuresis, laxative, removing jaundice subcutaneous ulcer, cholagogic and other effects.Control heat toxin, carbuncle swells, sore, interior Carbuncle, red eye, swell pain, damp and hot, jaundice, the puckery pain of dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, hot eyes, pharyngalgia, lung carbuncle, intestines Carbuncle, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.Control acute mastitis, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctivitis, cold, fever, Acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections etc..
Sweet wormwood:It is bitter in taste, it is pungent, it trembles with fear.Return liver, gallbladder channel, three burnt, kidney channels.Clear abnormal heat, cool blood is except steaming, relieving summer-heat, preventing malaria.With It generates heat in summer-heat evil, fever due to yin deficiency, night fever abating at dawn, hectic fever due to yin labor heat, malaria fever and chills, jaundice with damp-heat pathogen.
Reed root:Nature and flavor are sweet, tremble with fear.Distributed in lung channel, stomach.Effect clearing heat and promoting fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For pyreticosis polydipsia, Gastropyretic vomiting, cough with lung heat, lung carbuncle pyemesis, puckery pain of heat gonorrhea.
Campanulaceae:Nature and flavor are pungent, tepor, slightly poisonous.Facilitaing lung, relieving sore-throat, eliminating the phlegm, apocenosis.For coughing with a lot of sputum, chest distress, pharynx Bitterly, hoarse voice, lung carbuncle pyemesis, sore purulence is not at bursting.
Radix scutellariae:It is bitter in taste, it trembles with fear.Enter the heart, lung, courage, large intestine channel.Excess fire is rushed down, except damp and hot, hemostasis, tocolysis.High fever polydipsia is controlled, Cough with lung heat, damp-heat dysentery, jaundice, heat gonorrhea are spat, are defeated in battle, collapse, are leaked, red eye, swell pain, fetal irritability, carbuncle swells furunculosis.
Radix bupleuri:It is cold nature, bitter, pungent;Return liver warp, gallbladder channel, tool soothing liver-gallbladder dredge the effect of strongly fragrant gas solution, clearind deficient heat.For Cold, fever, fevers and chills alternate, malaria, stagnation of QI due to depression of the liver, sternal rib pain, rectal prolapse, uterus fall off, irregular menstruation.
Grass-leaved sweetflag:Acrid flavour, hardship, it is warm-natured.The thoughts of returning home, stomach.Have one's ideas straightened out, slit phlegm, qi-regulating is invigorated blood circulation, and relieve heat is dried.Epilepsy is controlled, Coma due to blocking of the respiratory system, pyreticosis coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, abdominal pain, wind-cold-dampness arthralgia, swollen ulcer drug, traumatic injury.
Compared with prior art, beneficial effects of the present invention:
Chinese medicine composition of the present invention has clearing heat and detoxicating, analgesia, diffusing lung, relieving exterior syndrome, invigorating the spleen tonifying Qi, the work(for adjusting body immunity Effect.Show reasonable medicine composition, simple for process, stable quality, at low cost through many experiments room and clinical practice inspection result Honest and clean, the features such as toxic side effect is small, be to have preferable effect to the prevention of poultry febrile disease.
Specific implementation mode
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common The every other embodiment that technical staff is obtained without creative efforts belongs to the model that the present invention protects It encloses.
Embodiment 1:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 3, sweet wormwood 12, Reed root 8, campanulaceae 16, radix scutellariae 72, radix bupleuri 12 and grass-leaved sweetflag 6.
The preparation method of above-mentioned anti virus herb composition, it includes the following steps:
(1)Weigh above-mentioned raw materials dandelion, sweet wormwood, reed root, campanulaceae, radix scutellariae, radix bupleuri and grass-leaved sweetflag, it is spare after decontamination;
(2)By the above-mentioned raw materials medicine mixing of the parts by weight, micronizer is added and is ground into 200-300 mesh powder, by powder Broken drug is soaked in water 40-60 minutes;(3)Soaked drug is put into microwave abstracting machine microwave 5 under the power of 600w Minute, Rotary Evaporators drying 20 minutes under the conditions of 85 DEG C are then placed in, it is finished product finally to crush.
Embodiment 2:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 2, sweet wormwood 14, Reed root 6, campanulaceae 19, radix scutellariae 62, radix bupleuri 14 and grass-leaved sweetflag 6.
The preparation method of the present embodiment is same as Example 1.
Embodiment 3:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 3, sweet wormwood 13, Reed root 7, campanulaceae 18, radix scutellariae 65, radix bupleuri 13 and grass-leaved sweetflag 7.
The preparation method of the present embodiment is same as Example 1.
Embodiment 4:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 4, sweet wormwood 12, Reed root 8, campanulaceae 17, radix scutellariae 67, radix bupleuri 11 and grass-leaved sweetflag 8.
The preparation method of the present embodiment is same as Example 1.
Embodiment 5:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 3.5, sweet wormwood 11, reed root 9, campanulaceae 16, radix scutellariae 70, radix bupleuri 10 and grass-leaved sweetflag 9.
The preparation method of the present embodiment is same as Example 1.
Embodiment 6:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 4, sweet wormwood 10, Reed root 10, campanulaceae 15, radix scutellariae 72, radix bupleuri 11 and grass-leaved sweetflag 10.
The preparation method of the present embodiment is same as Example 1.
Embodiment 7:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 5, sweet wormwood 9, Reed root 11, campanulaceae 14, radix scutellariae 74, radix bupleuri 10 and grass-leaved sweetflag 8.
The preparation method of the present embodiment is same as Example 1.
Embodiment 8:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 3, sweet wormwood 8, Reed root 8.5, campanulaceae 12, radix scutellariae 76, radix bupleuri 12 and grass-leaved sweetflag 9.
The preparation method of the present embodiment is same as Example 1.
Embodiment 9:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 4.5, sweet wormwood 7, reed root 9, campanulaceae 9, radix scutellariae 78, radix bupleuri 13 and grass-leaved sweetflag 10.
The preparation method of the present embodiment is same as Example 1.
Embodiment 10:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 5, sweet wormwood 6, Reed root 10, campanulaceae 8, radix scutellariae 79, radix bupleuri 12 and grass-leaved sweetflag 6.
The preparation method of the present embodiment is same as Example 1.
Embodiment 11:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 4, sweet wormwood 5, Reed root 6, campanulaceae 12, radix scutellariae 80, radix bupleuri 14 and grass-leaved sweetflag 8.
The preparation method of the present embodiment is same as Example 1.
Embodiment 12:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 3, sweet wormwood 6, Reed root 9, campanulaceae 16, radix scutellariae 65, radix bupleuri 12 and grass-leaved sweetflag 6.
The preparation method of the present embodiment is same as Example 1.
Embodiment 13:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 2.5, sweet wormwood 9.5, reed root 10, campanulaceae 13, radix scutellariae 68, radix bupleuri 12 and grass-leaved sweetflag 7.
The preparation method of the present embodiment is same as Example 1.
Embodiment 14:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 2, sweet wormwood 11, Reed root 6, campanulaceae 9, radix scutellariae 75, radix bupleuri 13 and grass-leaved sweetflag 8.
The preparation method of the present embodiment is same as Example 1.
Embodiment 15:
The present invention provides a kind of anti virus herb compositions, it is made of the raw material of following parts by weight:Dandelion 3.5, sweet wormwood 6, reed root 5, campanulaceae 8, radix scutellariae 80, radix bupleuri 10 and grass-leaved sweetflag 5.
The preparation method of the present embodiment is same as Example 1.
Clinical application
It is the explanation of product using effect of the present invention below:
Product release experiment is carried out to Xinxiang City chicken farm using the present invention, to show the drug of the present invention to warm property disease The therapeutic effect of sick packet influenza, 1200 diseased chickens of the present inventor couple have carried out the observation of clinical treatment.By taking this Invention drug, 0.3 gram of each medication of per kilogram of body weight poultry, boiling water add the appropriate uniform spice of ordinary water after washing open, make chicken group 2-3 small When eat up, continuous use 4 days.As a result 1120 are cured, cure rate 93.3%, 1182 effectively, and effective percentage is 98.5%, continuous to use Medicine 1-4 days can largely fully recover, and not stay any sequelae after controlling.Through experiment using drug of the present invention than general middle medication Effect improves 3 times or more, and cure rate is high, quick, cost-effective.
What has been described above is only a preferred embodiment of the present invention, it is noted that for those skilled in the art, Under the premise of not departing from general idea of the present invention, several changes and improvements can also be made, these should also be considered as the present invention's Protection domain.

Claims (5)

1. a kind of anti virus herb composition, it is characterised in that it is made of the raw material of following parts by weight:Dandelion 1-5, sweet wormwood 5-15, reed root 5-12, campanulaceae 8-20, radix scutellariae 60-80, radix bupleuri 10-15 and grass-leaved sweetflag 5-10.
2. anti virus herb composition according to claim 1, it is characterised in that it is made of the raw material of following parts by weight: Dandelion 1-3, sweet wormwood 10-15, reed root 5-8, campanulaceae 15-20, radix scutellariae 60-70, radix bupleuri 13-15 and grass-leaved sweetflag 5-8.
3. anti virus herb composition according to claim 1, it is characterised in that it is made of the raw material of following parts by weight: Dandelion 3-5, sweet wormwood 5-10, reed root 8-12, campanulaceae 8-15, radix scutellariae 70-80, radix bupleuri 10-13 and grass-leaved sweetflag 8-10.
4. anti virus herb composition according to claim 1, it is characterised in that it is made of the raw material of following parts by weight: Dandelion 3, sweet wormwood 12, reed root 8, campanulaceae 16, radix scutellariae 72, radix bupleuri 12 and grass-leaved sweetflag 6.
5. the preparation method of anti virus herb composition according to claim 1, it is characterised in that it includes the following steps:
(1)Weigh above-mentioned raw materials dandelion, sweet wormwood, reed root, campanulaceae, radix scutellariae, radix bupleuri and grass-leaved sweetflag, it is spare after decontamination;
(2)The above-mentioned raw materials medicine mixing of the parts by weight is added to being ground into 200-300 mesh powder in micronizer, The drug of crushing is soaked in water 40-60 minutes;(3)By soaked drug be put into microwave abstracting machine 400-600w work( Microwave 4-8 minutes under rate, Rotary Evaporators drying 20 minutes under the conditions of 70-85 DEG C are then placed in, it is finished product finally to crush.
CN201810982833.0A 2018-08-27 2018-08-27 A kind of anti virus herb composition and preparation method thereof Pending CN108743836A (en)

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Application publication date: 20181106