CN107596181A - A kind of electuary for treating kidney stone and preparation method thereof - Google Patents

A kind of electuary for treating kidney stone and preparation method thereof Download PDF

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Publication number
CN107596181A
CN107596181A CN201710705669.4A CN201710705669A CN107596181A CN 107596181 A CN107596181 A CN 107596181A CN 201710705669 A CN201710705669 A CN 201710705669A CN 107596181 A CN107596181 A CN 107596181A
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dried
electuary
stone
kidney stone
pain
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梁鹏
曾梓强
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Guangxi Herbal Medicine Health Products Co Ltd
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Guangxi Herbal Medicine Health Products Co Ltd
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Abstract

The present invention relates to a kind of electuary for treating kidney stone and preparation method thereof, using radix glycyrrhizae, cloves, dried orange peel, the root of kudzu vine, Poria cocos, Chinese cassia tree, adlay, mulberry leaf, cape jasmine, lotus leaf, radish seed, the taste Chinese medicine of fresh Rhizoma Imperatae 12, through extracting, being concentrated and dried, softwood processed, granulation, the step of drying prepare particle electuary, realize the quick niter of kidney stone illness, arrange the purpose of stone.The present invention is combined using above plurality of Chinese, and the proportioning of science is so that the electuary for preparing has the effect of anti-inflammation detumescence, promoting blood circulation and removing blood stasis, hemostasis and pain-relieving, diuresis and stone expeling, suitable for kidney stone patient, and it is evident in efficacy, have no toxic side effect, cost is cheap;Compatibility science of the present invention, it can substantially mitigate the pain of kidney stone patient, the spasm of ureter, urethra is alleviated, promote urinary function normal, there is significant row's stone, pain palliation efficacy.

Description

A kind of electuary for treating kidney stone and preparation method thereof
Technical field
The present invention relates to electuary field of pharmaceutical technology, particularly a kind of electuary for treating kidney stone and preparation method thereof.
Background technology
Kidney stone refers to the calculus for betiding kidney calices, renal plevis and renal plevis and urine output pipe jointing part.Majority is located in renal plevis kidney calices, Kidney essence calculus is rare.Plain film shows that there are single or multiple circular, ovals or obtuse triangle densification shadow, density Gao Erjun in kidney area It is even.How smooth edge is, but it is in mulberry fruit shape also to have rough.Kidney is the lithogenous main portions of urinary system shape, other any positions Calculus can be primary in kidney, ureteral calculi is almost all from kidney, and kidney stone is than other any position calculus Coup injury kidney is more easy to, therefore early diagnosis and therapy is extremely important.According to the difference of stone composition, kidney stone can divide oxalic acid Calcium calculus, calcium phosphate calculus, uric acid (lithate) calculus, struvite calculus, cystine stone and the class of purine calculus six.
Kidney stone is one kind of urolithiasis, is formed more in the summer of sweltering heat, because summer largely perspires, in addition it is de- in vivo Water, reduce urination, in addition summer exposed to the sunlight lower time grow, ultraviolet irradiation skin contribute to internal vitamin D and Vitamin A synthesis increases, and vitamin D and vitamin A can promote intestinal absorption calcium ion, drain calcium in urine and increase, in urine Calculus material is also easy to produce the nuclei of crystallization, so as to form calculus.Winter weather cold, the hydrouria of people, established microlith quilt Urine is washed away, and is moved down, and now causes renal colic symptom.So kidney stone is often " summer forms winter morbidity ".
At present, it is serious disease that kidney stone, which is not really, but in life constantly annoying patient and its household, more to patient Bring very big pain.Kidney stone main treatment at present has three kinds of Chinese medicine, rubble, an operation modes, in these methods, Chinese medicine Treatment is safest, and traditional Chinese medical science toxin expelling therapy can change the internal environment of human body, excludes to produce the Toxic of calculus in blood Matter, remove it and produce the material base of calculus.It can be allowed to dissolve compared with maximum size, broken diminish and excrete.Although Chinese medicine is controlled Treating kidney stone illness can treat both principal and secondary aspect of disease, and Small side effects;But Chinese medicine is comparatively laborious in use to be added, it is necessary to decoct Work brings many inconvenience to patient, it is necessary to there is professional processing technique of Chinese herbs to use;Therefore, how convenient and swift to make With treatment by Chinese herbs kidney stone illness, turn into the focus that vast traditional Chinese medical science worker pays close attention to always.
The content of the invention
It is an object of the invention to provide a kind of electuary for treating kidney stone and preparation method thereof, using radix glycyrrhizae, cloves, old Skin, the root of kudzu vine, Poria cocos, Chinese cassia tree, adlay, mulberry leaf, cape jasmine, lotus leaf, radish seed, the taste Chinese medicine of fresh Rhizoma Imperatae 12, it is dry through extracting, concentrating Softwood dry, processed, granulation, the step of drying prepare particle electuary, realize the quick niter of kidney stone illness, arrange the purpose of stone.
To achieve the above object, the technical solution adopted by the present invention is as follows:A kind of electuary for treating kidney stone, its raw material group It is divided into:Radix glycyrrhizae 8-16%, cloves 8-15%, dried orange peel 3-5%, root of kudzu vine 3-5%, Poria cocos 8-11%, Chinese cassia tree 6-8%, adlay 8-10%, mulberry leaf 7-9%, cape jasmine 3-5%, lotus leaf 3-5%, radish seed 6-10%, fresh Rhizoma Imperatae 10-20%.
A kind of method for the electuary for preparing above-mentioned treatment kidney stone, this method comprise the following steps:
1)Feeding:Each raw material is taken in following components ratio:Radix glycyrrhizae 8-16%, cloves 8-15%, dried orange peel 3-5%, root of kudzu vine 3-5%, Poria cocos 8-11%, Chinese cassia tree 6-8%, adlay 8-10%, mulberry leaf 7-9%, cape jasmine 3-5%, lotus leaf 3-5%, radish seed 6-10%, fresh Rhizoma Imperatae 10- 20%;
2)Extraction:By all impurity removings, cleaning, crushing is drained, is put in interlayer pot for solvent extraction, temperature 70 C~80 DEG C plus 8 times of amounts Water, 4h is extracted, takes leaching liquor to deposit;Again plus 8 times of amount water, temperature 70 C~80 DEG C extract 2h, merge decoction liquor twice, with 100 Mesh screen;
3)It is concentrated and dried:Filtrate is inserted in vacuum concentration pot, setting vacuum 97kPa, 55 DEG C~70 DEG C of temperature, is condensed into concentration Liquid, concentrate are the 25% of traditional Chinese medicinal components, then concentrate are obtained into extraction powder by being spray-dried;
4)Softwood processed:Extract powder 30% to add in kneader, add cane sugar powder 10%, dextrin 10%, dried starch 50%, use content 50% ethanol is modulated to softwood medicine and sticked together;
5)Granulation:The extruding that sticks together of softwood medicine is produced by wet shape particle using granulator;
6)Dry:Wet shape particle is inserted in 60 DEG C of pneumatic drier and dehydrated;
7)Whole grain:By dried particle after 1 10 mesh sieve whole grain, granule is obtained;
8)Sterilization packaging:Granule is inserted under ultraviolet to every bag of 20g after irradiating 2~3min to pack.
Radix glycyrrhizae:Radix glycyrrhizae is mild-natured, sweet, return 12 warps.There are removing toxic substances, eliminating the phlegm, analgesic, spasmolysis so that the pharmacological action such as anticancer. Major function:Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, lassitude hypodynamia, Palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.
Cloves:Sweet, pungent, extremely hot in nature, has a warm stomach, the effect of warm kidney, for stomach cold pain is swollen, hiccup, vomiting and diarrhoea, numbness pain, Colic, halitosis, toothache etc. are demonstrate,proved.
Chinese cassia tree:Acrid flavour, sweet, extremely hot in nature, return kidney, spleen, the heart, Liver Channel, have a mends fire supporing yang, let the fire back to its origin, eliminating cold to stop pain, Invigorate blood circulation, warming spleen and stomach, removing internal cold, the effect of promoting blood circulation.The Yang-function insufficiency of kidneyzang is controlled, cold weak pulse of limb, yang depletion collapse, diarrhea of suffering from abdominal pain, is trembled with fear Hernia run quickly globefish, waist and knee crymodynia, Amenorrhea abdominal mass, cloudy subcutaneous ulcer, streamer, and empty sun are floating more, the card such as heat in the upper and cold in the lower.
Dried orange peel:Regulating qi-flowing for strengthening spleen, in tune, eliminating dampness, resolving sputum.
The root of kudzu vine:It is cool in nature, it is sweet, pungent;There is clearing heat and cooling blood, purging intense heat and detonicating, inducing diaphoresis to bring down a fever, promote the production of body fluid, promoting eruption, Shengyang Zhixie it Effect.
Poria cocos:Cure mainly difficult urination, oedema turgor, phlegm and retained fluid cough is inverse, inverse, vomiting during early pregnancy of vomitting, diarrhea, seminal emission, stranguria with turbid discharge, palpitation with fear, strong Forget to wait disease.
Adlay:It is sweet, light, it is cool in nature.Returns spleen, stomach, lung channel.Favourable water penetration is wet, invigorating the spleen to arrest diarrhea, eliminating impediment, apocenosis, removing toxic substances The effect of dissipating bind.For oedema, tinea pedis, difficult urination, splenasthenic diarrhea, arthritis with fixed pain caused by dampness contraction, lung carbuncle, acute appendicitis;Wart, cancerous swelling.
Mulberry leaf:Alias, winter folium mori, frosted mulberry leaf;It is cold in nature, it is sweet, bitter.Return lung warp, Liver Channel.Cure mainly dispelling wind and heat from the body, clearing lung-heat profit It is dry, clear liver and improve vision.With controlling, anemopyretic cold, lung-heat type cough, dizziness headache, hot eyes are dim-sighted;Also antibacterial, diuresis, decompression, reduce blood Sugar etc. acts on.Belong to the cold-pungent and diaphoretic drugs of diaphoretic medicine subordinate classification.
Cape jasmine:It is bitter, cold, the thoughts of returning home, liver, lung, three burnt, stomach, heat-clearing, purging intense heat, cool blood, the heat for stagnant strongly fragrantization of losing heart, and profit three Jiao certainly shows disrespect on.
Lotus leaf:Contain a variety of alkaloids such as nuciferine, miltanthin and Nuciferine and vitamin C, polysaccharide.Have it is clearing heat and detoxicating, Cool blood, the effect of hemostasis.There are clearing summer-heat and damp, sending up the lucid yang, cooling blood and hemostasis and other effects simultaneously.
Radish seed:Alias SEMEN RAPHANI, trailing plants white chessman, turnip son, be crucifer radish mature seed, available for for Therapeutic diet stagnation, abdominal distention, constipation, stagnant rush down dysentery, phlegm, which are stopped up, breathes with cough.
Fresh Rhizoma Imperatae:It is cool blood, hemostasis, diuresis, antibacterial, antiviral, hepatitis viruse is effectively killed, its contained sylvite has again Good diuresis, oedema is treated, cool blood, hemostasia effect, glomerulus vasopermeability can be improved, controls blood urine.《Book on Chinese herbal medicine》 Say its tonifying middle-Jiao and Qi, diuresis, Yellow River harnessing subcutaneous ulcer oedema.Zhang Xichun is said:Lalang grass rhizome color is hollow in vain, arround have 12 apertures on slit bamboo or chopped wood, as The twelve channels and collaterals of people, therefore logical internal organs can be declared, the water on fluent channels and collaterals and the sharp whole body.
The present invention is combined using above plurality of Chinese, and there is the electuary that the proportioning of science to prepare anti-inflammatory to disappear The effect of swollen, promoting blood circulation and removing blood stasis, hemostasis and pain-relieving, promoting the circulation of qi dissipating bind, diuresis and stone expeling, suitable for kidney stone patient, and it is evident in efficacy, it is nontoxic Side effect, cost are cheap;It compatibility science of the present invention, can substantially mitigate the pain of kidney stone patient, make the spasm of ureter, urethra Alleviated, promote urinary function normal, there is significant row's stone, pain palliation efficacy.
Embodiment
The present invention is described in detail with reference to specific embodiment.
Embodiment 1
A kind of method for the electuary for preparing above-mentioned treatment kidney stone, this method comprise the following steps:
1)Feeding:Each raw material is taken in following components ratio:Radix glycyrrhizae 16%, cloves 15%, dried orange peel 5%, the root of kudzu vine 5%, Poria cocos 9%, Chinese cassia tree 7%th, adlay 10%, mulberry leaf 9%, cape jasmine 3%, lotus leaf 3%, radish seed 8%, fresh Rhizoma Imperatae 10%;
2)Extraction:By all impurity removings, cleaning, crushing is drained, is put in interlayer pot for solvent extraction, temperature 70 C adds 8 times of amount water, extraction 4h, leaching liquor is taken to deposit;Again plus 8 times of amount water, 0 DEG C of temperature 70 C extract 2h, merge decoction liquor twice, with 100 mesh screens;
3)It is concentrated and dried:Filtrate is inserted in vacuum concentration pot, setting vacuum 97kPa, 55 DEG C of temperature, is condensed into concentrate, dense Contracting liquid is the 25% of traditional Chinese medicinal components, then concentrate is obtained into extraction powder by being spray-dried;
4)Softwood processed:Extract powder 30% to add in kneader, add cane sugar powder 10%, dextrin 10%, dried starch 50%, use content 50% ethanol is modulated to softwood medicine and sticked together;
5)Granulation:The extruding that sticks together of softwood medicine is produced by wet shape particle using granulator;
6)Dry:Wet shape particle is inserted in 60 DEG C of pneumatic drier and dehydrated;
7)Whole grain:By dried particle after 1 10 mesh sieve whole grain, granule is obtained;
8)Sterilization packaging:Granule is inserted under ultraviolet to every bag of 20g after irradiating 2min to pack.
Embodiment 2
A kind of method for the electuary for preparing above-mentioned treatment kidney stone, this method comprise the following steps:
1)Feeding:Each raw material is taken in following components ratio:Radix glycyrrhizae 12%, cloves 10%, dried orange peel 4%, the root of kudzu vine 4%, Poria cocos 11%, Chinese cassia tree 8%th, adlay 9%, mulberry leaf 7%, cape jasmine 5%, lotus leaf 5%, radish seed 10%, fresh Rhizoma Imperatae 15%;
2)Extraction:By all impurity removings, cleaning, crushing is drained, is put in interlayer pot for solvent extraction, 75 DEG C plus 8 times amount water of temperature, extraction 4h, leaching liquor is taken to deposit;Again plus 8 times of amount water, 75 DEG C of temperature extract 2h, merge decoction liquor twice, with 100 mesh screens;
3)It is concentrated and dried:Filtrate is inserted in vacuum concentration pot, setting vacuum 97kPa, temperature 60 C, is condensed into concentrate, dense Contracting liquid is the 25% of traditional Chinese medicinal components, then concentrate is obtained into extraction powder by being spray-dried;
4)Softwood processed:Extract powder 30% to add in kneader, add cane sugar powder 10%, dextrin 10%, dried starch 50%, use content 50% ethanol is modulated to softwood medicine and sticked together;
5)Granulation:The extruding that sticks together of softwood medicine is produced by wet shape particle using granulator;
6)Dry:Wet shape particle is inserted in 60 DEG C of pneumatic drier and dehydrated;
7)Whole grain:By dried particle after 1 10 mesh sieve whole grain, granule is obtained;
8)Sterilization packaging:Granule is inserted under ultraviolet to every bag of 20g after irradiating 2.5min to pack.
Embodiment 3
A kind of method for the electuary for preparing above-mentioned treatment kidney stone, this method comprise the following steps:
1)Feeding:Each raw material is taken in following components ratio:Radix glycyrrhizae 10%, cloves 15%, dried orange peel 3%, the root of kudzu vine 3%, Poria cocos 8%, Chinese cassia tree 6%th, adlay 10%, mulberry leaf 8%, cape jasmine 5%, lotus leaf 5%, radish seed 7%, fresh Rhizoma Imperatae 20%;
2)Extraction:By all impurity removings, cleaning, crushing is drained, is put in interlayer pot for solvent extraction, 80 DEG C plus 8 times amount water of temperature, extraction 4h, leaching liquor is taken to deposit;Again plus 8 times of amount water, 80 DEG C of temperature extract 2h, merge decoction liquor twice, with 100 mesh screens;
3)It is concentrated and dried:Filtrate is inserted in vacuum concentration pot, setting vacuum 97kPa, temperature 70 C, is condensed into concentrate, dense Contracting liquid is the 25% of traditional Chinese medicinal components, then concentrate is obtained into extraction powder by being spray-dried;
4)Softwood processed:Extract powder 30% to add in kneader, add cane sugar powder 10%, dextrin 10%, dried starch 50%, use content 50% ethanol is modulated to softwood medicine and sticked together;
5)Granulation:The extruding that sticks together of softwood medicine is produced by wet shape particle using granulator;
6)Dry:Wet shape particle is inserted in 60 DEG C of pneumatic drier and dehydrated;
7)Whole grain:By dried particle after 1 10 mesh sieve whole grain, granule is obtained;
8)Sterilization packaging:Granule is inserted under ultraviolet to every bag of 20g after irradiating 3min to pack.

Claims (2)

1. a kind of electuary for treating kidney stone, it is characterised in that its raw material components is:Radix glycyrrhizae 8-16%, cloves 8-15%, dried orange peel 3- 5%th, root of kudzu vine 3-5%, Poria cocos 8-11%, Chinese cassia tree 6-8%, adlay 8-10%, mulberry leaf 7-9%, cape jasmine 3-5%, lotus leaf 3-5%, radish seed 6- 10%th, fresh Rhizoma Imperatae 10-20%.
A kind of 2. method of the electuary of the treatment kidney stone prepared described in claim 1, it is characterised in that:This method includes following Step:
1)Feeding:Each raw material is taken in following components ratio:Radix glycyrrhizae 8-16%, cloves 8-15%, dried orange peel 3-5%, root of kudzu vine 3-5%, Poria cocos 8-11%, Chinese cassia tree 6-8%, adlay 8-10%, mulberry leaf 7-9%, cape jasmine 3-5%, lotus leaf 3-5%, radish seed 6-10%, fresh Rhizoma Imperatae 10- 20%;
2)Extraction:By all impurity removings, cleaning, crushing is drained, is put in interlayer pot for solvent extraction, temperature 70 C~80 DEG C plus 8 times of amounts Water, 4h is extracted, takes leaching liquor to deposit;Again plus 8 times of amount water, temperature 70 C~80 DEG C extract 2h, merge decoction liquor twice, with 100 Mesh screen;
3)It is concentrated and dried:Filtrate is inserted in vacuum concentration pot, setting vacuum 97kPa, 55 DEG C~70 DEG C of temperature, is condensed into concentration Liquid, concentrate are the 25% of traditional Chinese medicinal components, then concentrate are obtained into extraction powder by being spray-dried;
4)Softwood processed:Extract powder 30% to add in kneader, add cane sugar powder 10%, dextrin 10%, dried starch 50%, use content 50% ethanol is modulated to softwood medicine and sticked together;
5)Granulation:The extruding that sticks together of softwood medicine is produced by wet shape particle using granulator;
6)Dry:Wet shape particle is inserted in 60 DEG C of pneumatic drier and dehydrated;
7)Whole grain:By dried particle after 1 10 mesh sieve whole grain, granule is obtained;
8)Sterilization packaging:Granule is inserted under ultraviolet to every bag of 20g after irradiating 2~3min to pack.
CN201710705669.4A 2017-08-17 2017-08-17 A kind of electuary for treating kidney stone and preparation method thereof Pending CN107596181A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112439030A (en) * 2019-09-04 2021-03-05 王忠民 Medicine for quickly reducing uric acid
CN116098971A (en) * 2021-11-10 2023-05-12 广西本草坊保健品有限公司 Health tea for auxiliary treatment of kidney stones and preparation method thereof

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CN103977348A (en) * 2014-05-09 2014-08-13 天津太平洋制药有限公司 Medicament for treating renal calculus
CN104547685A (en) * 2014-12-26 2015-04-29 青岛市中心医院 Traditional Chinese medicine preparation for treating kidney stone and urinary stone
CN104547661A (en) * 2014-12-09 2015-04-29 李国华 Medicine for treating lithangiuria and kidney calculi
CN104922514A (en) * 2015-06-12 2015-09-23 广东恒诚制药有限公司 Preparation method and application of Jieshitong tablets
CN105497214A (en) * 2014-09-23 2016-04-20 刘方旭 Traditional Chinese medicine kidney benefiting and calculus removing medicinal instant granules and preparation method thereof
CN106729089A (en) * 2016-12-29 2017-05-31 武汉万松堂健康产业有限公司 It is a kind of to protect health preserving tea of kidney effect and preparation method thereof with calculus dissolving and excreting, guarantor's courage

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103977348A (en) * 2014-05-09 2014-08-13 天津太平洋制药有限公司 Medicament for treating renal calculus
CN105497214A (en) * 2014-09-23 2016-04-20 刘方旭 Traditional Chinese medicine kidney benefiting and calculus removing medicinal instant granules and preparation method thereof
CN104547661A (en) * 2014-12-09 2015-04-29 李国华 Medicine for treating lithangiuria and kidney calculi
CN104547685A (en) * 2014-12-26 2015-04-29 青岛市中心医院 Traditional Chinese medicine preparation for treating kidney stone and urinary stone
CN104922514A (en) * 2015-06-12 2015-09-23 广东恒诚制药有限公司 Preparation method and application of Jieshitong tablets
CN106729089A (en) * 2016-12-29 2017-05-31 武汉万松堂健康产业有限公司 It is a kind of to protect health preserving tea of kidney effect and preparation method thereof with calculus dissolving and excreting, guarantor's courage

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112439030A (en) * 2019-09-04 2021-03-05 王忠民 Medicine for quickly reducing uric acid
CN116098971A (en) * 2021-11-10 2023-05-12 广西本草坊保健品有限公司 Health tea for auxiliary treatment of kidney stones and preparation method thereof

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Application publication date: 20180119