CN101708315A - Chinese medicinal preparation for treating headache and preparation method thereof - Google Patents
Chinese medicinal preparation for treating headache and preparation method thereof Download PDFInfo
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- CN101708315A CN101708315A CN200910218282A CN200910218282A CN101708315A CN 101708315 A CN101708315 A CN 101708315A CN 200910218282 A CN200910218282 A CN 200910218282A CN 200910218282 A CN200910218282 A CN 200910218282A CN 101708315 A CN101708315 A CN 101708315A
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Abstract
The invention discloses a Chinese medicinal preparation for treating a headache, which is a medicament prepared from 38 raw medicinal materials such as szechuan lovage rhizome, Chinese angelica, red paeony root, root of rehmannia, peach seed, safflower and the like. A preparation method 1 comprises the following steps: (1) preparing aqueous extract of raw material medicaments; (2) preparing an oral liquid from the aqueous extract obtained by the step (1) by the conventional method; (3) drying and crashing the aqueous extract obtained by the step (1), and passing the powders through a screen to prepare medicament extract powders,; and (4) preparing tablets, granules, pills, soluble granules or capsules with the medicament extraction powders. A preparation method 2 comprises the following steps: (1) crashing the raw material medicaments; (2) passing the powders through a screen to obtain screen under the flow; (3) disinfecting and sterilizing to obtain raw powders; and (4) preparing tablets, granules, pills, soluble granules or capsules with the raw powders. The Chinese medicinal preparation for treating the headache has quick response and high curative effect, mainly treats angioneurotic headache, migraine, headache and dizziness caused by hypertension, grey hair and hair loss and the like, and has obvious curative effect on cerebrovascular disease, such as the headache, the dizziness and the like, caused by chronic cerebral circulation insufficiency. The raw medicinal materials adopted by the Chinese medicinal preparation are common Chinese medicaments, have low production cost and have no toxic or side effects basically.
Description
Technical field
The present invention relates to a kind of medicine with Chinese medicine preparation and preparation method thereof, concrete is a kind of Chinese medicine preparation for the treatment of headache and preparation method thereof.
Background technology
Headache promptly refers to because diseases caused by exogenous pathogenic factor or internal injury, cause venation contraction contracture or lose foster, clear key unfavorable caused be a kind of common disease of feature with the conscious head pain of patient, can occur in the multiple acute and chronic diseases, also be the tendency that some relevant disease increases the weight of or worsens sometimes.The traditional Chinese medical science is divided into headache due to invasion of exogenous pathogens and headache due to internal injury two classes with headache, and headache due to invasion of exogenous pathogens is how careless because of daily life, and sitting crouches work as wind, experience wind, cold, wet, exopathogen such as heat, based on ailment said due to cold or exposure.Exopathogen is attacked in meridians from table, on violate mountain peak top, the gas of clear sun is obstructed, QI and blood is not smooth, checks the network road, and causes headache; Wind being the primary exopathogen is held seasonal epidemic pathogens more under the arm and is fallen ill.If hold the cold-evil under the arm, the cold coagulation stasis, the network road is hindered, and sends out to be headache; If hold pathogenic heat under the arm, scorching on the wind heat, invasion empties, and sends out to be headache; If hold damp under the arm, wet illiteracy empties, and clear sun is not opened up, and causes headache.The pathogenic factor of headache due to internal injury is relevant with liver,spleen,kidney." the brain being the reservoir of the marrow ", brain mainly rely on liver, kidney essense blood moistens and supports and the transporting and transforming function of the spleen and stomach essence of water and grain, fill in brain on the defeated cloth QI and blood.Because of in the liver person, one hinders because of feelings will, the liver failing to maintain the normal flow of QI, strongly fragrant and fire-transformation, pathogen upward attacking orifices in head and cause headache.One contains impairment of YIN because of fire, liver lose moisten foster, or deficiency of kidney-YIN, the kidney failing to nourish the liver causes hepatic and renal YIN deficiency, excessive rising of liver-YANG, pathogen upward attacking orifices in head and cause headache.Because of in the kidney person, how by innate deficiency, kidney essense is lost for a long time, and brains are hollow and cause headache.But also deficiency of YIN affecting YANG, decline of kidney-YANG, clear sun is not opened up, and is headache.Because of in the spleen person, the hungry full overstrain of polyphyly, or after being ill, puerperal asthenia, weakness of the spleen and stomach, biochemical not enough, or after losing blood, nutrient blood is empty loses, can not go up flourishly in the brains venation, and cause headache.Or eating and drinking without temperance, the delicious food of being addicted to drink, dysfunction of the spleen in transportation is given birth in the phlegm-damp, and last illiteracy empties and checks positive clearly and cause headache.
Western medicine is divided into migraine, tension headache, cluster headache and chronic paroxysmal hemicrania etc. with headache.
Summary of the invention:
The objective of the invention is to propose a kind of new Chinese medicine preparation that can effectively treat headache, concrete is the technical scheme of a kind of Chinese medicine preparation for the treatment of headache and preparation method thereof.
Technical scheme of the present invention is, a kind of Chinese medicine preparation for the treatment of headache is the medicament of being made by following weight parts proportion raw material medical material: Rhizoma Chuanxiong 6-60, Radix Angelicae Sinensis 6-30, Radix Paeoniae Rubra 6-30, Radix Rehmanniae 6-30, Semen Persicae 1-15, Flos Carthami 1-15, Radix Salviae Miltiorrhizae 6-60, Fructus Crataegi 6-60, Radix Polygoni Multiflori 6-60, Radix Paeoniae Alba 6-60, Radix Angelicae Dahuricae 6-60, Rhizoma Et Radix Notopterygii 3-30, Rhizoma Gastrodiae 6-60, Ramulus Uncariae Cum Uncis 3-30, Pheretima 6-60, Bombyx Batryticatus 6-60, Rhizoma Corydalis 6-60, Scorpio 0.3-15, Scolopendra 1-15, Radix Curcumae 6-60, Ci Jili 6-60, Spica Prunellae 6-60, Flos Chrysanthemi 6-60, Herba Asari 1-9, Fructus Aurantii Immaturus 3-60, Radix Platycodonis 3-60, Radix Achyranthis Bidentatae 6-60, Rhizoma Ligustici 3-30, Fructus Viticis 3-60, Radix Scutellariae 3-60, Radix Puerariae 3-60, Concha Haliotidis 3-60, Fructus Mume 6-60, Herba Leonuri 6-60, Rhizoma Arisaematis 3-60, HUANGWEIZI 6-60, Rhizoma Acori Graminei 6-60, Radix Polygalae 6-60.
Said medicament is oral liquid, granule, powder, capsule, electuary, tablet, pill.
A kind of preparation method for the treatment of the Chinese medicine preparation of headache, be made up of following steps: (1) is made as water content according to a conventional method with the crude drug of claim 1 is 10% aqueous extract, (2) aqueous extract of using step (1) to make according to a conventional method is made as oral liquid, (3) the aqueous extract drying that step (1) is obtained, pulverizing, mistake at least 200 mesh sieves, extracting screen underflow is an extract drugs powder, and the extract drugs powder that (4) use step (3) to make according to a conventional method is made as tablet, granule, pill, electuary or the capsule in the oral agents.
A kind of preparation method for the treatment of the Chinese medicine preparation of headache, it is characterized in that being made by following steps: (1) is with the described crude drug sieve of claim 1 dedust soil, pulverize, (2) cross at least 200 mesh sieves, extracting screen underflow, (3) sterilization, the pulvis of making a living, the fecula powder that (4) use step (3) to make according to a conventional method is made as tablet, granule, pill, electuary or the capsule in the oral agents.
The traditional Chinese medical science generally is divided into headche due to wind-cold, headache due to pathogenic wind-heat, headache due to deficiency of the kidney, headache due to deficiency of blood, headache due to deficiency of QI, the turbid headache of expectorant, headache due to blood stasis to the dialectical diagnosis and treatment of having a headache.Treatment headache dialectical guide: blood circulation promoting and blood stasis dispelling, suppressing the hyperactive liver to relieve the wind syndrome, nourish blood sensible.The present invention mainly identifies and corrects according to Chinese medicine and executes the principle of controlling, the tame chief of the many doctors of collection, extensively adopt the strange medicine wonderful recipe in the rich Yunnan various nationalities of receipts area, based on pathogenetic understanding and the Therapeutic Principle of Chinese medicine to headache, reference is the pharmacological research achievement at all times, and screening blood circulation promoting and blood stasis dispelling, suppressing the hyperactive liver to relieve the wind syndrome, the sensible natural Chinese medicine that nourishes blood are by the theory of Chinese medical science prescription, skim the cream off milk, and form through the clinical practice summary of long-term diagnosis and treatment case.
Prescription analysis of the present invention: in the side, the hot temperature of Rhizoma Chuanxiong is walked to scurry, top, up mountain peak, and the descending sea of blood, but promoting blood circulation to disperse blood clots and relieves pain can draw the up women's head-ornaments of all medicines again, and through focus has the title of controlling the headache panacea; Radix Angelicae Sinensis, Radix Paeoniae Alba easing the affected liver nourish blood, and along reaching blood vessels, the suffering that can help Rhizoma Chuanxiong is dry; Rhizoma Ligustici, Fructus Viticis dispelling wind and relieving; Scorpio, Pheretima, Bombyx Batryticatus are searched to pick and are scraped network, and the effect of logical deep and remote pain relieving for the indispensable medicine of the nerve intractable headache of treatment obstinate, is associated with all medicines of blood circulation promoting and blood stasis dispelling, the suppressing the hyperactive liver that dispels the wind, the meridian dredging, qi and blood invigorating, and analgesic effect is excellent.In the side, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Radix Paeoniae Rubra, the Radix Rehmanniae, Semen Persicae, Flos Carthami, Radix Salviae Miltiorrhizae, Fructus Crataegi, Radix Polygoni Multiflori are blood circulation promoting and blood stasis dispelling, sensible monarch drug nourishes blood, invigorates blood circulation; Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Radix Curcumae, the Radix Paeoniae Alba, Semen Cassiae, Flos Chrysanthemi, Spica Prunellae, Ci Jili, Herba Leonuri, Scorpio, Pheretima, Bombyx Batryticatus, Radix Salviae Miltiorrhizae, suppressing the hyperactive liver to relieve the wind syndrome are ministerial drug, and Herba Leonuri, Pheretima activating blood and promoting diuresis are assistant; Radix Achyranthis Bidentatae promoting blood circulation, conducting blood to flow downwards; The Radix Angelicae Dahuricae, walk Yangming Channel, Radix Bupleuri and go into few sun with Fructus Aurantii Immaturus circulation of qi promoting soothing liver-QI; Radix Puerariae, Rhizoma Et Radix Notopterygii walk Taiyang channel; Fructus Viticis, Herba Asari, Rhizoma Ligustici are messenger drug; The Radix Scutellariae heat clearing and damp drying.All medicine cooperations have blood circulation promoting and blood stasis dispelling, suppressing the hyperactive liver to relieve the wind syndrome, sensible headache, dizziness, the alopecia function controlled nourishes blood.
Modern medicine study is thought, how angioneurotic headache is because of the outer nervus vasculairs insufficiency of accommodation of intracranial, due to cerebral tissue, microcirculation are not smooth.Modern pharmacological research shows, Rhizoma Chuanxiong energy sedation-analgesia, the cerebral blood flow increasing amount, the microcirculation that improves cerebral tissue is not smooth, reduce serum cholesterol and anticoagulant and prevent thrombosis, can effectively alleviate arteriosclerotic degree, have effects such as expansion of cerebral vascular simultaneously, to hypertension complicated headache, vascular headache, cerebral concussion sequela, headache, anemic headache all have good result.Rhizoma Chuanxiong can be expanded small artery, venule, and platelet aggregation when effectively suppressing tissue ischemia increases the microcirculatory blood volume of brain, can significantly reduce the cerebral tissue ischemic lesions, improves nervous system dysfunction.Radix Angelicae Sinensis energy antiplatelet aggregation, relaxing smooth muscle, antithrombotic forms, and has calmness, analgesia, antiinflammatory and blood vessel dilating effect.Radix Curcumae, the Radix Angelicae Dahuricae, Radix Puerariae have the microcirculation improvement effect, and small artery and venule are all had remarkable dilating effect.The Radix Paeoniae Alba can the alleviating vascular contracture.The Radix Angelicae Dahuricae, Herba Asari can excited vasomotor centers, regulate the vasomotion effect, and Radix Puerariae can increase the blood capillary motional amplitude, improves local little blood flow, improves cerebral circulation and peripheral circulation, coronary artery dilator and cerebrovascular.The calmness of Radix Angelicae Dahuricae tool, analgesic activity.Radix Salviae Miltiorrhizae and Rhizoma Chuanxiong have remarkable increase blood capillary netting index, quicken blood flow, increase the local microcirculation hemoperfusion, reduce plasma viscosity, improve hemorheological property, and the brain vessel blood amount is increased.Radix Paeoniae Alba energy blood vessel dilating, releasing vascular smooth muscle spasm.Scorpio, Pheretima, Bombyx Batryticatus, Scolopendra shrink cerebrovascular antagonism, can adjust cerebrovascular function, reaches spasmolytic and aim of alleviating pain.Medicine of the present invention is pressed the principle organic assembling of monarch, and synergism all has curative effect preferably, treating both the principal and secondary aspects of a disease to various types of headaches.Can effectively improve the microcirculatory effect of brain, strengthen cerebrovascular vigor, can make cerebrovascular and even whole body size blood capillary unclog and readjust unobstructed.The present invention is rapid-action, and the curative effect height cures mainly angioneurotic headache, migraine, hypertension complicated headache dizziness, turns white and deal with etc., and cerebrovascular disease such as the headache that causes because of cerebral blood supply insufficiency, dizziness are had tangible curative effect.The crude drug that the present invention adopts is common Chinese commonly used, and cost of manufacture is low, has no side effect substantially.
The each 5-100ml of oral liquid of the present invention, day obeys oral 3 times, or chip select agent, granule, pill, powder, capsule, electuary etc. are wherein a kind of, each 3-10 gram, day obeys 3 times, various dosage forms can be used alternatingly, and extract powder and with each dosage form medicine and fecula powder and identical with each dosage form survival dose of its preparation of its preparation.Treating 20 days is a course of treatment, light disease 1-3 course of treatment, serious symptom 3-5 the course of treatment.
Attention: 1, under the doctor instructs, use; 2, the hyperpietic can not withdraw depressor.
Clinical trial data of the present invention:
Adopt the present invention to follow the tracks of treatment headche due to wind-cold, headache due to pathogenic wind-heat, headache due to deficiency of the kidney, headache due to deficiency of blood, headache due to deficiency of QI, the turbid headache of expectorant, headache due to blood stasis totally 100 examples, wherein, male's 217 examples, women's 283 examples, age 18-80 year, morbidity back 1-20.
Tcm diagnosis, headache when the headche due to wind-cold person falls ill, the aversion to wind fear of cold, the pain increased to meet wind; Severe headache when headache due to pathogenic wind-heat person falls ill and expanding, heating, thirsty; Headache Ban You Shi-hyun was dizzy when the headache due to deficiency of the kidney person fell ill, and lumbago is aching and limp, and is refreshing weary unable; Headache Ban You Shi-hyun was dizzy when the headache due to deficiency of blood person fell ill, and palpitation and uneasiness is refreshing weary unable, pale complexion; Headache increased the weight of shortness of breath and fatigue with dizziness when tired when the headache due to deficiency of QI person fell ill; Headache and dizziness when the turbid headache person of expectorant falls ill, uncomfortable in chest, the vomiting and nausea sputum; Headache due to blood stasis person has a headache and does not prolongedly heal, and sore spot is fixing not to be moved, pain as being stabbed, and partly patient's head has trauma history.
The patient is through Western medicine diagnose, angioneurotic headache patient 22 examples, migraineur's 31 examples, dizzy patient's 28 examples of hypertension complicated headache, the headache that cerebral blood supply insufficiency causes, dizzy patient 19 examples.Wherein the patient that the course of disease is long has and turns white, deals with and the alopecia areata symptom.
Therapeutic Method: the each 10-20ml of oral liquid, day clothes 3 times, each 3-10 gram such as granule, powder, capsule, electuary, day clothes 3 times.
Took medicine three days, the recovery from illness patient of clinical symptoms complete obiteration is 42 people, total cure rate 42%.The produce effects patient that clinical symptoms disappears substantially is 36 people, total obvious effective rate 36%.Effective patient that clinical symptoms partly disappears is 17 people, total effective rate 17%.Clinical symptoms does not have 5 people of improvement, total inefficiency 5%.In therapeutic process, do not see obvious adverse effect and toxic and side effects, do not have to find to have the phenomenon of liver, kidney, lung, spleen, stomach upset.Partly the recovery from illness patient of alopecia begins to grow New Development.
The specific embodiment
Sequence number | The Chinese medicine title | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 |
??1 | Rhizoma Chuanxiong (g) | ??40 | ??6 | ??60 | ??20 |
??2 | Radix Angelicae Sinensis (g) | ??6 | ??30 | ??10 | ??20 |
??3 | Radix Paeoniae Rubra (g) | ??30 | ??20 | ??6 | ??10 |
??4 | The Radix Rehmanniae (g) | ??6 | ??30 | ??10 | ??20 |
??5 | Semen Persicae (g) | ??10 | ??1 | ??5 | ??15 |
??6 | Flos Carthami (g) | ??5 | ??15 | ??10 | ??1 |
??7 | Radix Salviae Miltiorrhizae (g) | ??20 | ??6 | ??60 | ??40 |
??8 | Fructus Crataegi (g) | ??40 | ??60 | ??20 | ??6 |
Sequence number | The Chinese medicine title | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 |
??9 | Radix Polygoni Multiflori (g) | ??6 | ??20 | ??40 | ??60 |
??10 | The Radix Paeoniae Alba (g) | ??60 | ??40 | ??6 | ??20 |
??11 | The Radix Angelicae Dahuricae (g) | ??20 | ??6 | ??40 | ??60 |
??12 | Rhizoma Et Radix Notopterygii (g) | ??30 | ??20 | ??10 | ??3 |
??13 | Rhizoma Gastrodiae (g) | ??6 | ??20 | ??60 | ??40 |
??14 | Ramulus Uncariae Cum Uncis (g) | ??30 | ??20 | ??3 | ??10 |
??15 | Pheretima (g) | ??6 | ??20 | ??40 | ??60 |
??16 | Bombyx Batryticatus (g) | ??40 | ??60 | ??20 | ??6 |
??17 | Rhizoma Corydalis (g) | ??20 | ??6 | ??60 | ??40 |
??18 | Scorpio (g) | ??8 | ??15 | ??0.3 | ??1 |
??19 | Scolopendra (g) | ??5 | ??1 | ??15 | ??10 |
??20 | Radix Curcumae (g) | ??60 | ??40 | ??6 | ??20 |
??21 | Ci Jili (g) | ??40 | ??60 | ??20 | ??6 |
??22 | Spica Prunellae (g) | ??60 | ??40 | ??6 | ??20 |
??23 | Flos Chrysanthemi (g) | ??6 | ??20 | ??60 | ??40 |
??24 | Herba Asari (g) | ??9 | ??5 | ??1 | ??3 |
??25 | Fructus Aurantii Immaturus (g) | ??3 | ??20 | ??40 | ??60 |
??26 | Radix Platycodonis (g) | ??60 | ??20 | ??3 | ??40 |
??27 | Radix Achyranthis Bidentatae (g) | ??40 | ??60 | ??20 | ??3 |
??28 | Rhizoma Ligustici (g) | ??10 | ??3 | ??20 | ??30 |
??29 | Fructus Viticis (g) | ??60 | ??40 | ??20 | ??3 |
??30 | Radix Scutellariae (g) | ??20 | ??3 | ??40 | ??60 |
Sequence number | The Chinese medicine title | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 |
??31 | Radix Puerariae (g) | ??3 | ??20 | ??60 | ??40 |
??32 | Concha Haliotidis (g) | ??40 | ??60 | ??20 | ??3 |
??33 | Fructus Mume (g) | ??60 | ??40 | ??6 | ??20 |
??34 | Herba Leonuri (g) | ??20 | ??6 | ??40 | ??60 |
??35 | Rhizoma Arisaematis (g) | ??3 | ??20 | ??60 | ??40 |
??36 | HUANGWEIZI (g) | ??40 | ??60 | ??6 | ??20 |
??37 | Rhizoma Acori Graminei (g) | ??60 | ??40 | ??20 | ??6 |
??38 | Radix Polygalae (g) | ??6 | ??20 | ??60 | ??40 |
1, a kind of preparation method for the treatment of the Chinese medicine preparation of headache, form by following steps:
(1) press table 1 and be equipped with crude drug, all medicines are dry product, and it is 10% aqueous extract that crude drug is made as water content according to a conventional method,
(2) aqueous extract of using step (1) to make according to a conventional method is made as oral liquid,
(3) the aqueous extract drying that step (1) is obtained, pulverizing, mistake at least 200 mesh sieves, extracting screen underflow is an extract drugs powder,
(4) the extract drugs powder of using step (3) to make according to a conventional method is made as tablet, granule, pill, electuary or the capsule in the oral agents.Granule, pill, electuary, every bag contains drug powder 3-5 gram; Tablet, every contains drug powder 0.2-0.5 gram; Capsule, every drug powder 0.2-0.5 gram; Powder, every bag of 3-5 gram.
2, a kind of preparation method for the treatment of the Chinese medicine preparation of headache, make by following steps:
(1) press table 1 and be equipped with crude drug, all crude drug is a dry product, and crude drug sieve dedust soil is pulverized,
(2) cross at least 200 mesh sieves, extracting screen underflow,
(3) sterilization, the pulvis of making a living,
(4) the fecula powder of using step (3) to make according to a conventional method is made as tablet, granule, pill, electuary or the capsule in the oral agents.Concentrated solution is concentrated according to a conventional method, dry, pulverizing are made as the powder that treatment is caught a cold, and every bag of 3-5 restrains.Granule, pill, electuary, every bag contains drug powder 3-5 gram; Tablet, every contains drug powder 0.2-0.5 gram; Capsule, every drug powder 0.2-0.5 gram; Powder, every bag of 3-5 gram.
Claims (4)
1. Chinese medicine preparation for the treatment of headache is characterized in that it is the medicament of being made by following weight parts proportion raw material medical material:
Rhizoma Chuanxiong 6-60 Radix Angelicae Sinensis 6-30 Radix Paeoniae Rubra 6-30 Radix Rehmanniae 6-30
Semen Persicae 1-15 Flos Carthami 1-15 Radix Salviae Miltiorrhizae 6-60 Fructus Crataegi 6-60
Radix Polygoni Multiflori 6-60 Radix Paeoniae Alba 6-60 Radix Angelicae Dahuricae 6-60 Rhizoma Et Radix Notopterygii 3-30
Rhizoma Gastrodiae 6-60 Ramulus Uncariae Cum Uncis 3-30 Pheretima 6-60 Bombyx Batryticatus 6-60
Rhizoma Corydalis 6-60 Scorpio 0.3-15 Scolopendra 1-15 Radix Curcumae 6-60
Ci Jili 6-60 Spica Prunellae 6-60 Flos Chrysanthemi 6-60 Herba Asari 1-9
Fructus Aurantii Immaturus 3-60 Radix Platycodonis 3-60 Radix Achyranthis Bidentatae 6-60 Rhizoma Ligustici 3-30
Fructus Viticis 3-60 Radix Scutellariae 3-60 Radix Puerariae 3-60 Concha Haliotidis 3-60
Fructus Mume 6-60 Herba Leonuri 6-60 Rhizoma Arisaematis 3-60 HUANGWEIZI 6-60
Rhizoma Acori Graminei 6-60 Radix Polygalae 6-60.
2. a kind of Chinese medicine preparation for the treatment of headache according to claim 1 is characterized in that described medicament is oral liquid, granule, powder, capsule, electuary, tablet, pill.
3. preparation method for the treatment of the Chinese medicine preparation of headache is characterized in that being made up of following steps:
(1) crude drug of claim 1 being made as according to a conventional method water content is 10% aqueous extract,
(2) aqueous extract of using step (1) to make according to a conventional method is made as oral liquid,
(3) the aqueous extract drying that step (1) is obtained, pulverizing, mistake at least 200 mesh sieves, extracting screen underflow is an extract drugs powder,
(4) the extract drugs powder of using step (3) to make according to a conventional method is made as tablet, granule, pill, electuary or the capsule in the oral agents.
4. preparation method for the treatment of the Chinese medicine preparation of headache is characterized in that being made by following steps:
(1) with the described crude drug sieve of claim 1 dedust soil, pulverize,
(2) cross at least 200 mesh sieves, extracting screen underflow,
(3) sterilization, the pulvis of making a living,
(4) the fecula powder of using step (3) to make according to a conventional method is made as tablet, granule, pill, electuary or the capsule in the oral agents.
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