CN104173919A

CN104173919A - Traditional Chinese medicine for treating hypertension and preparation method thereof

Info

Publication number: CN104173919A
Application number: CN201410373015.2A
Authority: CN
Inventors: 金丽丽
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-07-25
Filing date: 2014-07-25
Publication date: 2014-12-03

Abstract

The invention relates to a traditional Chinese medicine for treating hypertension and a preparation method thereof. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 20 parts of uncaria, 10 parts of the seed of Chinese dodder, 15 parts of the root of kudzu vine, 8 parts of red paeony root, 8 parts of notopterygium root and 8 parts of curcuma zedoary. The clinical experiment proves that the traditional Chinese medicine can be used for safely and effectively treating hypertension.

Description

One is used for the treatment of hypertensive Chinese medicine and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine, be specifically related to one and be used for the treatment of hypertensive Chinese medicine and preparation method thereof.

Background technology

Hypertension claims again essential hypertension or essential hypertension, means and gets rid of all known reasons, and taking hypertension as principal character, the systemic disease changing with the organ physiology such as blood vessel, the heart, brain, kidney, pathologic.For there is in early days headache, dizziness, tinnitus, cardiopalmus, dim eyesight, absent minded, hypomnesis, numbness of hands and feet, fatigue and weak, the easy symptom such as irritated in clinical manifestation, these symptoms mostly are due to higher nerve functional disorder, and its weight and blood pressure increase degree can be inconsistent; Later stage blood pressure often continues in higher level, and with impaired performances of target organ such as brain, the heart, kidneys, what these target organs were impaired in early days can be asymptomatic, finally causes dysfunction, and exhaustion even occurs.

Any age of primary disease all can fall ill, but multiple with person in middle and old age or obese people.Primary disease cardiovascular complication occurs with dead danger higher.

Hypertension belongs to global refractory disease, its pathogeny is completely not clear and definite so far, western medicine has diuretic, beta-blocker, calcium channel blocker, angiotensin converting enzyme inhibitor, angiotensin-ii receptor blocker etc. at present, but its side effect is all larger.

Primary disease belongs to the traditional Chinese medical science " dizzy ", " headache ", " liver-yang " category according to its clinical manifestation, and the generation of the primary disease often factor such as deficient with disorder of emotion, eating and drinking without temperance, internal injury is relevant.

Medical material present Research involved in the present invention is as follows:

Ramulus Uncariae Cum Uncis [source] this product is dicotyledon medicine Maguireothamnus speciosus Ramulus Uncariae Cum Uncis or Uncaria sinensis (Oliv.) Havil. and the buckle branch that belongs to various plants together thereof.The gather twig of buckle of spring, autumn, cuts off the rattan of Wugou, dries, or puts after steaming in pot and dry.[nature and flavor] are sweet, bitter, are slightly cold.[return through] returns liver, heart channel.[function cures mainly] heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind.Main infantile convulsion, night cry, intenseness of heat wind symptom, eclamposia; Dizziness due to hyperactivity of liver-YANG, liver-fire distending pain in the head.[usage and dosage] 6～30g.

Semen Cuscutae [source] this product is the seed of dicotyledon scammonia section plant Semen Cuscutae, southern Semen Cuscutae, cuscuta japonica Choisy etc.The 9-10 month gathers in the crops, and the mature fruit of gathering, dries, and gets seed, the shell of winnowing with a dustpan, impurity.[nature and flavor] are pungent, sweet, flat.[return through] returns liver,kidney,spleen warp.[function cures mainly] the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, Gu tire stopping leak.Main soreness of waist and knee joint; Seminal emission, sexual impotence, premature ejaculation, sterile; Quench one's thirst, stranguria with turbid discharge, the enuresis; Blurred vision tinnitus; Frequent fetal movement, miscarriage; Have loose bowels.[usage and dosage] 6～15g.

Radix Puerariae [source] this product is the tuber of legume pueraria lobata or Radix Puerariae rattan.Tuber is dug out, remove tendril, cut root head and plant, remove silt, scrape off rough bark, be cut into the oblique sheet that 1.5-2cm is thick, dry or dry.[nature and flavor] are sweet, pungent, flat.[return through] returns spleen, stomach, lung, urinary bladder channel.[function cures mainly] expelling pathogenic factors from muscles for reducing heat, delivers and examines, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal.Main fever caused by exogenous pathogens, rigidity pain on the head and nape; Measles from the beginning of, rash goes out not smooth; Epidemic febrile disease is thirsty, diabetes; Have loose bowels, dysentery; Hypertension; Coronary heart disease.[usage and dosage] 10～15g.

Radix Paeoniae Rubra [source] this product is the root of Paeoniaceae plant peony, CHUANSHAO medicine, Paeonia obovata Maxim., hair leaf Paeonia obovata Maxim., Paeonia mairei Lévl., Paeonia anomala and tuber Radix Paeoniae.The 8-9 month excavates, and removes aerial parts and earth, when dry in the sun is extremely half-dried, is bundled into wisp, shines to foot dry.[nature and flavor] hardship, is slightly cold.[return through] returns liver, spleen channel.[function cures mainly] clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.Main maculae caused by violent heat pathogen; Hematemesis and epistaxis, discharging fresh blood stool; Conjunctival congestion and swelling pain, carbuncle skin infection; Amenorrhea, dysmenorrhea, metrorrhagia and leukorrhagia stranguria with turbid discharge; The stagnant hypochondriac pain of the stasis of blood, hernia abdominal mass is gathered; Injury from falling down.[usage and dosage] 4～10g.[attention] blood deficiency is without disease and the routed careful clothes of person of carbuncle of the stasis of blood.

Rhizoma Et Radix Notopterygii [source] this product is rhizome and the root of samphire Rhizoma Et Radix Notopterygii or Radix et Rhizoma Notopterygii.Fall autumn after Seedling and cut off aerial parts to rudiment in early spring, take rhizome, tremble clean silt, cut removing LU, except fibrous root, be cut into the long pipe nipple of 10-13cm, dry or dry.[nature and flavor] are pungent, bitter, warm in nature.[return through] returns bladder, kidney channel.[function cures mainly] exterior cold of faling apart, wind-damp dispelling, sharp joint, pain relieving.Main affection of exogenous wind-cold, has a headache lossless; Mimeograph cold-damp numbness, edema due to wind pathogen edema; Sore swollen toxin.[usage and dosage] 3～10g.

Rhizoma Curcumae [source] this product is the rhizome of zingiberaceous plant Rhizoma Curcumae, Guangxi zedoary and RADIX CURCUMAE.In 12 months, the last ten-days period, when aerial parts is withered, excavate root, remove the earth on rhizome, clean, put in pot and to steam or to boil about 15min, dry or dry, hit fibrous root.[nature and flavor] are pungent, bitter, temperature.[return through] returns liver, spleen channel.[function cures mainly] circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.Main vim and vigour are pained, eating accumulation, abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhea, lump in the abdomen tumor mass in the abdomen, traumatic injury.[usage and dosage] 3～10g.

Summary of the invention

The present invention aims to provide one and is used for the treatment of hypertensive Chinese medicine and preparation method thereof, by selecting suitable medical material and proportioning thereof, reaches the hypertensive object of safe and effective healing.

In order to achieve the above object, the present invention is by the following technical solutions:

One is used for the treatment of hypertensive Chinese medicine, it is characterized in that, it is to be prepared from by the raw medicinal material of following weight proportion: 20 parts of Ramulus Uncariae Cum Uncis, 10 parts of Semen Cuscutae, 15 parts of Radix Puerariaes, 8 parts of Radix Paeoniae Rubra, 8 parts of Rhizoma Et Radix Notopterygiis, 8 parts of Rhizoma Curcumae.

Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:

1, physical data

Inventor in October, 2010～2013 are collected outpatient service and hyperpietic's 65 examples of being in hospital altogether between year February, be divided at random treatment group 33 examples and matched group 32 examples, treatment group man 10 examples, female's 23 examples, 43～75 years old age, 60.9 years old mean age, the course of disease 2～10 years; Matched group man 10 examples, female's 22 examples, 40～76 years old age, 61.7 years old mean age, the course of disease 1～8 year.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.

Diagnostic criteria

In the situation that not using antihypertensive drug, systolic pressure is greater than, equals 140 millimetress of mercury, and diastolic pressure is greater than, equals 90 millimetress of mercury; Previously there is history of hypertension, now use antihypertensive drug, though existing blood pressure does not reach above-mentioned level, also should be diagnosed as hypertension.

2, test method

2.1 Therapeutic Method

The decoct that the oral the present invention for the treatment of group makes according to specific embodiment 1, every day 3 times.8 weeks courses for the treatment of.

The oral Folium Ginkgo of matched group, takes according to its description.8 weeks courses for the treatment of.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterion of therapeutical effect

Effective: diastolic pressure declines more than 10 millimetress of mercury and reaches normal range; Though or diastolic pressure is not down to normally, oneself declines more than 20 millimetress of mercury.

Effective: diastolic pressure declines not as good as 10 millimetress of mercury, but has reached normal range; Diastolic pressure is treated front decline 10～19 millimetress of mercury, but does not reach normal range.

Invalid: not reach above standard person.

3.2 therapeutic outcomes are in table 1.

Table 1 liang group curative effect comparison

Group	n	Effective	Effectively	Invalid	Total effective rate (%)	Serious adverse reaction example
							Treatment group	33	20	8	5	84.8％	0
Matched group	32	15	6	11	65.6％	0

Visible, the medicine that the present invention makes can safe and effective treatment hypertension, has promotional value.

Detailed description of the invention

In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Specific embodiment 1

Take: 20 grams of Ramulus Uncariae Cum Uncis, 10 grams of Semen Cuscutae, 15 grams of Radix Puerariaes, 8 grams of Radix Paeoniae Rubra, 8 grams of Rhizoma Et Radix Notopterygiis, 8 grams of Rhizoma Curcumae; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of one day consumption of normal adult.

Be used for the treatment of hypertension.Oral, every bu morning, noon and afternoon take for three times.

Specific embodiment 2

Take: 20 grams of Ramulus Uncariae Cum Uncis, 10 grams of Semen Cuscutae, 15 grams of Radix Puerariaes, 8 grams of Radix Paeoniae Rubra, 8 grams of Rhizoma Et Radix Notopterygiis, 8 grams of Rhizoma Curcumae; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, pack, must meet the powder of one day consumption of normal adult.

Be used for the treatment of hypertension.Oral, take once every day.

Specific embodiment 3

Take: 20 grams of Ramulus Uncariae Cum Uncis, 10 grams of Semen Cuscutae, 15 grams of Radix Puerariaes, 8 grams of Radix Paeoniae Rubra, 8 grams of Rhizoma Et Radix Notopterygiis, 8 grams of Rhizoma Curcumae; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, dry, incapsulate shell, must meet the capsule of one day consumption of normal adult.

Be used for the treatment of hypertension.Oral, every bu is taken for twice sooner or later.

Claims

1. be used for the treatment of a hypertensive Chinese medicine, it is characterized in that, it is to be prepared from by the raw medicinal material of following weight proportion: 20 parts of Ramulus Uncariae Cum Uncis, 10 parts of Semen Cuscutae, 15 parts of Radix Puerariaes, 8 parts of Radix Paeoniae Rubra, 8 parts of Rhizoma Et Radix Notopterygiis, 8 parts of Rhizoma Curcumae.

2. be as claimed in claim 1ly used for the treatment of hypertensive Chinese medicine, it is characterized in that, its preparation method is: take: 20 parts of Ramulus Uncariae Cum Uncis, 10 parts of Semen Cuscutae, 15 parts of Radix Puerariaes, 8 parts of Radix Paeoniae Rubra, 8 parts of Rhizoma Et Radix Notopterygiis, 8 parts of Rhizoma Curcumae; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.

3. be as claimed in claim 1ly used for the treatment of hypertensive Chinese medicine, it is characterized in that, its preparation method is: take: 20 parts of Ramulus Uncariae Cum Uncis, 10 parts of Semen Cuscutae, 15 parts of Radix Puerariaes, 8 parts of Radix Paeoniae Rubra, 8 parts of Rhizoma Et Radix Notopterygiis, 8 parts of Rhizoma Curcumae; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.

4. be as claimed in claim 1ly used for the treatment of hypertensive Chinese medicine, it is characterized in that, its preparation method is: take: 20 parts of Ramulus Uncariae Cum Uncis, 10 parts of Semen Cuscutae, 15 parts of Radix Puerariaes, 8 parts of Radix Paeoniae Rubra, 8 parts of Rhizoma Et Radix Notopterygiis, 8 parts of Rhizoma Curcumae; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, dry, incapsulate shell, obtain capsule; Above-mentioned part all refers to weight portion.