CN1555839A - Medicne for treating primary hypertension and its preparation method - Google Patents
Medicne for treating primary hypertension and its preparation method Download PDFInfo
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- CN1555839A CN1555839A CNA2003101210051A CN200310121005A CN1555839A CN 1555839 A CN1555839 A CN 1555839A CN A2003101210051 A CNA2003101210051 A CN A2003101210051A CN 200310121005 A CN200310121005 A CN 200310121005A CN 1555839 A CN1555839 A CN 1555839A
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- essential hypertension
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Abstract
A Chinese medicine for treating primary hypertension is prepared from 7-13 Chinese-medicinal materials including pueraria root, uncaria stem with hooks, prunella spike, earthworm, etc. Its advantage is high curative effect (93% for cure rate).
Description
Affiliated field:
The present invention relates to the hypertensive pharmaceutical composition of a kind of treatment, particularly a kind of is the medicine of the treatment essential hypertension made of raw material with the animals and plants Chinese herbal medicine.
Background technology:
Essential hypertension is a kind of in the hypertension, is for secondary hypertension is sick.Its pathology basis is an atherosclerosis, coronary atherosclerotic heart disease etc.The state of an illness has overall relevance and progressively expansionary, how with brain, and maincenter, the heart, kidney target organ and channels tissue produce the physiological function pathological change of distinct program, mainly bring out cardiovascular and cerebrovascular disease unusually and threat to life with the blood flow supply-demand relationship.At all kinds of patients with hypertension of China the trend of development is year by year arranged, and younger gradually.This essential hypertension of current treatment mainly relies on Western medicine.But the Western medicine toxic side effect is big, and curative effect is single, and cure rate is low.Chinese medicine also addresses this problem making great efforts.The applicant once applied for a Chinese invention patent, 01128978.3 of application number is called " treating hypertensive medicine and preparation method thereof ", its scheme is based on motherland's medical science to hypertensive understanding and Therapeutic Principle, be suitable for the compound recipe pharmacological property of Chinese medicine, to the human body negative and positive, QI and blood, internal organs, meridians, cold and heat etc. are whole to be adjusted, it is long-pending that the utilization drug for invigorating blood circulation and eliminating stasis picks the stasis of blood of scraping meridians, it is unimpeded to improve the blood vessel meridians, the employing current meridian qi and blood of promoting the circulation of blood medicine of regulating the flow of vital energy, improve the four stages in the course of an epidemic febrile disease relation, be suitable for the active ingredient of Chinese medicine medicine, force lipoprotein decomposition in the blood, bring high blood pressure down, thereby to treating the cardiovascular and cerebrovascular disease that hypertension and hypertension cause, coronary heart disease, atherosclerosis, cardiovascular and cerebrovascular vessel have special efficacy unusually.The scheme of this application has produced good effect in practice, but along with further discovering, research has more specifically meaning to a certain disease medicament more targetedly, that is to say that providing a kind of is extremely important at hyperpietic traditional Chinese medical science medicine.
Summary of the invention:
The object of the present invention is to provide hyperpietic medicine of a kind of Chinese medicine and preparation method thereof.
Solution of the present invention is based on motherland's medical science to hyperpietic understanding and Therapeutic Principle, is suitable for the compound recipe pharmacology rerum natura of Chinese medicine.Essential hypertension is equivalent to categories such as dizzy, the headache, apoplexy of Chinese medicine and pharmacy, intend summing up the classical prescription that to treat these diseases, utilize the effective active components of Chinese herbal medicine, treat essential hypertension with the compound recipe pharmacological property of Chinese herbal medicine and reach other intercurrent diseases that cause thus.
The present invention program's medicine is made (consumption is a weight portion) by following component
RADIX PUERARIAE 10-20 Ramulus Uncariae Cum Uncis 10-20 Spica Prunellae 10-20
Radix Gentianae Macrophyllae 10-20 Pheretima 8-16 capillary wormwood 10-20
And Fructus Tribuli 8-16 Radix Scutellariae 8-16 car Radix Saposhnikoviae 8-16
Treat Herba Asari 2-10 Rhizoma Et Radix Notopterygii 6-12 Radix Rehmanniae 6-12
At least a among the Rhizoma Atractylodis 10-20.
The preferred weight proportion scope of pharmaceutical formulation of the present invention is:
RADIX PUERARIAE 12-18 Ramulus Uncariae macrophyllae 12-18 Spica Prunellae 12-18
Radix Gentianae Macrophyllae 12-18 Pheretima 10-14 capillary wormwood 12-18
Fructus Tribuli 10-14 Radix Scutellariae 10-14 car Radix Saposhnikoviae 10-14
Treat Herba Asari 4-8 Rhizoma Et Radix Notopterygii 8-10 Radix Rehmanniae 8-10
Rhizoma Atractylodis 12-18
Optimum weight part proportioning of medicine of the present invention is:
RADIX PUERARIAE 15 Ramulus Uncariae macrophyllae 15 Spica Prunellaes 15
Radix Gentianae Macrophyllae 15 Pheretimas 12 capillary wormwoods 15
Fructus Tribuli 12 Radix Scutellariae 12 car Radix Saposhnikoviaes 12
Treat Herba Asari 6 Rhizoma Et Radix Notopterygiis 9 Radix Rehmanniae 9 Rhizoma Atractylodis 15
The method of above-mentioned each component being made medicine of the present invention is:
1, RADIX PUERARIAE is cut into slices after concocting give birth to use;
2, Ramulus Uncariae macrophyllae is cut into slices to give birth to after concocting and is used;
3, Spica Prunellae is given birth to after concocting and is used;
4, Radix Gentianae Macrophyllae is given birth to after concocting and is used;
5, fry smelling removal behind the Pheretima steeping in wine;
6, capillary wormwood gives birth to after concocting and uses;
7, Fructus Tribuli deburring adds saline and fries usefulness;
8, fry behind the Radix Scutellariae steeping in wine;
9, the car Radix Saposhnikoviae gives birth to after concocting and uses;
10, treat Herba Asari and after concocting, give birth to usefulness;
11, Rhizoma Et Radix Notopterygii gives birth to after concocting and uses;
12, use behind the Radix Rehmanniae parch to black;
13, Rhizoma Atractylodis are fried through strong yellow Tu Shui and are used;
14, with above-mentioned whole medicament components by after the described mixed, carry out ripening at 100 ℃-110 ℃, sterilization treatment 10-30 minute, get final product the powder medicine of treatment essential hypertension.Powder after the maturation process can be processed into any dosage form by the conventional treatment method of Chinese medicine, for example makes cream, ball, looses, decoction or capsule, to meet patient's the custom of taking.
The important feature of the present invention program's medicament is to contain the hyperpietic various active ingredients of treatment, and these composition roles comprise:
1, very strong bringing high blood pressure down arranged, blood lipid regulation, antiviral effect.
2, the analgesia of inducing sweat is arranged, expelling wind and removing dampness, clearing away heat-fire, the effect of promoting blood circulation of eliminating turbid pathogen with aromatics removing heat from blood.
3, suppressing the hyperactive liver to relieve the wind syndrome is arranged, the effect of diuretic kalium replenishment.
4, can improve heart and brain arteries blood flow, improve atherosclerosis, reduce serum cholesterol and B lipoprotein, prevent the blood vessel wall lipid accumulation.
5, this medicament suppresses and calmness alleviating hypertension patient simultaneous phenomenon by strengthening cortex.
Owing to have above effect, the present invention program's medicine to be particularly suitable for as the high blood of constitutional district patient cerebral arteriosclerosis patient and coronary heart disease of hypertension patient.Through clinical diagnosis and treatment statistics, the present invention program is through the clinical observation of 6000 routine systems, atherosis person's 2486 examples of hypertension cerebral artery vessel wherein, hypertension heart coronary artery atherosclerotic heart disease patient 834 examples, the essential hypertension person of sharing the weal and woe together 2680 examples.Male patient's 2480 examples wherein, female patient 3520 examples, age reckling 28 years old, maximum 94 years old, the highest patient's systolic pressure of blood pressure 210mmhg, diastolic pressure 130mmhg, the minimum patient's systolic pressure of blood pressure 140mmhg, diastolic pressure 95mmhg, lipoprotein all has imbalance in various degree in the blood.
Above-mentioned patient follows up a case by regular visits to 2 years time through taking the present invention program's medicament, and medicine time is the shortest 20 days, and is the longest 3 months.Suffer from simple property hyperpietic cure rate 93%, weak point person's recurrence medicine time.It is longer because of medicine time to suffer from the coronary heart disease of hypertension person, and hypertension all drops in normal range.The present invention treats the medicine effective percentage 100% of essential hypertension, cure rate 93%.
Now lift the curative effect of some indivedual case explanations medicine of the present invention again.
Case 1; Shen, the woman, 76 years old now, one village, Lu Ba township, Pengan County, Sichuan Province, patient's private prosecution just suffered from hypertension before 10 years, and long-term headache and dizzy through failing to respond to any medical treatment in many ways, comes institute to go to a doctor June 8 calendar year 2001.Blood pressure systolic pressure 220mmhg on inspection, diastolic pressure 130mmhg increases two horizontal fingers to the left through TV x-ray fluoroscopy left ventricle, arrhythmia, cholesterol 6.24mmH/L, triglyceride 1.7mmH/L HDL-C 1.04mmH/L, low-density lipoprotein cholesterol 4.16mmH/L.Be level Four hypertension after diagnosing, brain arteries and veins blood vessel scleratheroma aroused in interest, coronary heart disease.The diagnosis and treatment scheme is a blood pressure lowering,
Transfer blood fat, promoting blood circulation.Behind five doses of the medicaments through taking the present invention program, blood pressure is reduced to 120mmhg.75mmhg, after to change Radix Puerariae hook mattress soup into be powder, obey half a year continuously, now observed and do not seen the hypertension recurrence in 2 years 03 months, also participate in some physical works, healthy.
Case 2: Huang, the man 52 years old now, lives 15 villages, Da Fu township, South Sichuan county.Come institute to go to a doctor August 12 calendar year 2001.Private prosecution rose in 40 years old just suffers from hypertension, and long-term headache and dizzy is pressed 190mmhg/110mmhg, TV x-ray fluoroscopy heart not to have through having a blood test and thickened, and the rhythm of the heart is normal.Cholesterol 6.24mmH/L, triglyceride 1.7mmH/L, HDL-C 1.04mmH/L, low-density lipoprotein cholesterol 3.64mmH/L.
Be diagnosed as three grades of hypertension, cerebral artery vessel is atherosis.
Therapeutic scheme is blood pressure lowering, transfers blood fat, promoting blood circulation, takes this programme medicine Radix Puerariae hook mattress rushing agent first quarter moon, and blood pressure is reduced to 110mmhg/70mmhg, after blood pressure is normal, changes powder voluntarily into and takes continuously three months, follows up a case by regular visits to 2 years, and hypertension no longer recurs.
More than the above case, too numerous to enumerate.
Embodiment:
Take by weighing material by following proportioning:
4 kilograms of 4 kilograms of Spica Prunellaes of 4 kilograms of Ramulus Uncariae macrophyllae of RADIX PUERARIAE
4 kilograms of 3 kilograms of capillary wormwoods of 4 kilograms of Pheretimas of Radix Gentianae Macrophyllae
3 kilograms of 3 kilograms of car Radix Saposhnikoviaes of 3 kilograms of Radix Scutellariae of Fructus Tribuli
Treat 4 kilograms of 2 kilograms of Rhizoma Atractylodis of 2 kilograms of Radix Rehmanniae of 1 kilogram of Rhizoma Et Radix Notopterygii of Herba Asari
Claims (7)
1, the medicine of treatment essential hypertension, it is characterized in that: it is the medicament of being made by the following weight parts proportioning:
RADIX PUERARIAE 10-20 Ramulus Uncariae macrophyllae 10-20 Spica Prunellae 10-20
Radix Gentianae Macrophyllae 10-20 Pheretima 8-16 capillary wormwood 10-20
And Fructus Tribuli 8-16 Radix Scutellariae 8-16 car Radix Saposhnikoviae 8-16
Treat Herba Asari 2-10 Rhizoma Et Radix Notopterygii 6-12 Radix Rehmanniae 6-12
At least a among the Rhizoma Atractylodis 10-20.
2, the medicine of treatment essential hypertension according to claim 1 is characterized in that: the preferred weight proportion of pharmaceutical formulation of the present invention is:
RADIX PUERARIAE 12-18 Ramulus Uncariae macrophyllae 12-18 Spica Prunellae 12-18
Radix Gentianae Macrophyllae 12-18 Pheretima 10-14 capillary wormwood 12-18
Fructus Tribuli 10-14 Radix Scutellariae 10-14 car Radix Saposhnikoviae 10-14
Treat Herba Asari 4-8 Rhizoma Et Radix Notopterygii 8-10 Radix Rehmanniae 8-10
Rhizoma Atractylodis 12-18
3, the medicine of treatment essential hypertension according to claim 1 is characterized in that: optimum weight part proportioning of medicine of the present invention is:
RADIX PUERARIAE 15 Ramulus Uncariae macrophyllae 15 Spica Prunellaes 15
Radix Gentianae Macrophyllae 15 Pheretimas 12 capillary wormwoods 15
Fructus Tribuli 12 Radix Scutellariae 12 car Radix Saposhnikoviaes 12
Treat Herba Asari 6 Rhizoma Et Radix Notopterygiis 9 Radix Rehmanniae 9 Rhizoma Atractylodis 15
4, according to the medicine of claim 1,2 or 3 described treatment essential hypertensions, it is characterized in that: said medicament is a said dosage form on any pharmaceutics.
5, the medicine of treatment essential hypertension according to claim 4 is characterized in that: said medicament is cream, ball, loose, decoction or capsule.
6, a kind of preparation method for the treatment of the medicine of essential hypertension is characterized in that:
(1), RADIX PUERARIAE is cut into slices after concocting give birth to use;
(2), Ramulus Uncariae macrophyllae is cut into slices to give birth to after concocting and is used;
(3), Spica Prunellae is given birth to after concocting and is used;
(4), Radix Gentianae Macrophyllae is given birth to after concocting and is used;
(5), fry smelling removal behind the Pheretima steeping in wine;
(6), capillary wormwood gives birth to after concocting and uses;
(7), the Fructus Tribuli deburring, add saline and fry to use;
(8), fry behind the Radix Scutellariae steeping in wine;
(9), the car Radix Saposhnikoviae gives birth to after concocting and uses;
(10), treat Herba Asari and after concocting, give birth to usefulness;
(11), Rhizoma Et Radix Notopterygii gives birth to after concocting and uses;
(12), use behind the Radix Rehmanniae parch to black;
(13), Rhizoma Atractylodis are fried through strong yellow Tu Shui and are used;
7, the preparation method of the medicine of essential hypertension according to claim 6, it is characterized in that: after above-mentioned whole medicament components are pressed described mixed, carry out ripening at 100 ℃-110 ℃, sterilization treatment 10-30 minute, get final product the treatment essential hypertension the powder medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101210051A CN100569252C (en) | 2003-12-30 | 2003-12-30 | The medicine and the preparation method of treatment essential hypertension |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101210051A CN100569252C (en) | 2003-12-30 | 2003-12-30 | The medicine and the preparation method of treatment essential hypertension |
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| Publication Number | Publication Date |
|---|---|
| CN1555839A true CN1555839A (en) | 2004-12-22 |
| CN100569252C CN100569252C (en) | 2009-12-16 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2003101210051A Expired - Fee Related CN100569252C (en) | 2003-12-30 | 2003-12-30 | The medicine and the preparation method of treatment essential hypertension |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104173919A (en) * | 2014-07-25 | 2014-12-03 | 金丽丽 | Traditional Chinese medicine for treating hypertension and preparation method thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015068112A2 (en) * | 2013-11-06 | 2015-05-14 | Anil Kumar Sharma | Herbal composition for treatment of hypertension and associated disorders |
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2003
- 2003-12-30 CN CNB2003101210051A patent/CN100569252C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104173919A (en) * | 2014-07-25 | 2014-12-03 | 金丽丽 | Traditional Chinese medicine for treating hypertension and preparation method thereof |
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| Publication number | Publication date |
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| CN100569252C (en) | 2009-12-16 |
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Granted publication date: 20091216 Termination date: 20101230 |