CN1557402A - Chinese herbal medicine preparation and its preparing process and application - Google Patents
Chinese herbal medicine preparation and its preparing process and application Download PDFInfo
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Abstract
The present invention relates to the Chinese herbal medicine preparation including digestion liquid inside common nepenthes bag as main medicine component and pharmaceutical acceptable supplementary medicine material and its preparation process and application. By means of the digestion liquid inside common nepenthes bag, the medicine, after being introduced into blood vessel, can dissolve the embolism, hardened clots and inflammation factor inside blood vessel, decompose fat, cholesterol, saccharide and other composite macro molecular compound, promote blood circulation and dredge microcirculation. In addition, the medicine has common nepenthes and pubescent holly root as auxiliary medicine component, and this makes the medicine safe and high in treating effect. The present invention may be used together with blood vessel dilating Western medicine for wide use in treating various cardiac and cerebral vascular diseases.
Description
Technical field
The present invention relates to a kind of is the preparation of feedstock production with the Chinese herbal medicine, the invention still further relates to the preparation method and the application thereof of said preparation.
Background technology
As everyone knows, multiple chronic disease has become the formidable enemy who threatens middle-aged and elderly people health such as blood vessel infraction, diabetes, coronary heart disease, apoplexy etc. such as hypertension and the heart, brain, kidneys, and the patient who dies from these diseases every year is countless.According to theory of Chinese medical science: middle-aged and elderly people why easily suffers from these diseases and cureless main cause is because after people in middle age, the function of health is progressively degenerated, so that the heart, brain, tiny blood vessels such as kidney are blocked gradually, influence the circulation of blood, make the histiocyte can't homergy, microcirculation disturbance takes place, thereby cause hypertension, hyperlipidemia, the tiny blood vessels infraction, diabetes and coronary heart disease, the generation of multiple disease such as apoplexy, so the traditional Chinese medical science is said " source that blood stasis is all kinds of diseases and ailments ", and the blood stagnation of QI and blood may bring about pain, therefore these diseases to have been treated, at first must make vessel inner blood unimpeded, and the existing medicine that is used for the treatment of these diseases is mainly Western medicine, although Western medicine can be received certain curative effect for blood circulation for the moment, but Western medicine is cured the symptoms, not the disease, need take medicine throughout one's life, careless slightly repeatedly the outbreak in causing hemiplegia or cerebral thrombosis, even get killed, moreover in secular drug administration process, serious damage heart and brain kidney or cause the high or low excessively imbalance of YIN and YANG of some element and cause the vicious cycle of disease.Although the Chinese patent medicine that yet has some to treat these diseases, effect are not fairly obvious, therefore also be difficult to be accepted by extensive patients.
Herba nepenthis is the carnivorism herbaceous plant, in the vertical capsule of middle arteries and veins of its leaf weakly acidic Digestive system is arranged, and small worm falls in the capsule when inhaling honey and digested (simple and clear dictionary P1306 introduction biology) by Digestive system.The pharmacy literature record has the effect of clearing away heat and promoting diuresis, inflammation-diminishing and cough-controlling with its all herbal medicine, but the Digestive system of having no precedent in its capsule of record has pharmacologic action.(because Herba nepenthis is when harvesting, transportation and pharmacy, the Digestive system major part in its capsule is spilt from its operculum, and remaining is then volatilized has fallen.)
Summary of the invention
The object of the present invention is to provide digesting and dissolving compound macromolecular substances such as fat in endovascular embolus, plaque and inflammatory factor and the decomposition blood constituent, cholesterol, saccharide and promoted circulation, the microcirculatory Chinese herbal and crude drugs preparations of mediation of blood and its production and application effectively in the diseases such as a kind of blood vessel infraction that can be widely used in treatment and prophylaxis of hypertension and the heart, brain, kidney, diabetes, coronary heart disease, apoplexy.
Solution of the present invention is based on China's medical science to pathogenetic understanding of various chronic diseases and Therapeutic Principle, self character with reference to modern pharmacological research achievement and natural plants, select for use to have and to digest and to dissolve small insect and other toy and resolve into atomic thin material and directly absorb Digestive system in the plant Herba nepenthis capsule that becomes the idiotrophic material as principal agent, make and take the back and feed endovascular Digestive system and can effectively digest and dissolve endovascular embolus, fat in plaque and inflammatory factor (external and all provable its effect of body innerlich anwenden) and the decomposition blood constituent, cholesterol, compound macromolecular substances such as saccharide (makes blood constituent recover normal, but can not destroy erythrocyte) and promoted the circulation of blood effectively, the mediation microcirculation.Simultaneously because its cooperation selects for use the Radix Ilicis Pubescentis that can effectively overcome the toxic and side effects of Digestive system and have the Herba nepenthis of clearing away heat-damp and promoting diuresis characteristics and have blood circulation and channel invigorating, an eliminating inflammation and expelling toxin effect as ministerial drug, utilized the comprehensive pharmacology coordinative role of each natural plants fully, the toxic and side effects of medicine of the present invention is reduced to minimum level, guarantee edible safety, and further strengthened its therapeutic effect.
Chinese herbal and crude drugs preparations of the present invention comprises the medicament of being made by Digestive system in the principal agent Herba nepenthis capsule and pharmaceutically acceptable ancillary drug.
For toxic and side effects and further its therapeutic effect of strengthening of effectively overcoming Digestive system, above-mentioned ancillary drug comprises Herba nepenthis, the Radix Ilicis Pubescentis as ministerial drug.
For the immunity of enhancing body, protect each organ, above-mentioned ancillary drug also includes Spica Prunellae as adjuvant drug, very heavy group, Radix Salviae Miltiorrhizae, Radix Codonopsis, Concha Haliotidis and as propylparaben, the cyclamate of additive.
Wherein, the weight proportion of each raw material in the per unit consumption of preparation preparation of the present invention is: (is unit with the gram)
Digestive system: 10-120 Herba nepenthis: 3-15 Radix Ilicis Pubescentis: 3-15
Very heavy group of Spica Prunellae: 2-15: 2-15 Radix Salviae Miltiorrhizae: 2-15
Concha Haliotidis: 2-10 Radix Codonopsis 2-15 cyclamate: an amount of
Propylparaben: an amount of
The preferred weight proportioning of each raw material in the per unit consumption of preparation preparation of the present invention is: (is unit with the gram)
Digestive system: 50-60 Herba nepenthis: 5-12 Radix Ilicis Pubescentis: 3-12
Very heavy group of Spica Prunellae: 3-10: 4-12 Radix Salviae Miltiorrhizae: 9-15
Concha Haliotidis: 3-10 cyclamate: an amount of propylparaben: an amount of
Radix Codonopsis: 6-15
The method of above-mentioned raw materials being made preparation of the present invention is:
(1), the preparation of principal agent Digestive system: the interior Digestive system of pig cage capsule of returning of will gathering earlier removes slag through multiple times of filtration, after its filtrate boiled with big fire, boiled 10-20 minute with little fiery constant temperature, and in last five minutes of boiling, put into an amount of sterilization and the antiseptical propylparaben of being used for, stir evenly and it is fully dissolved and obtain Digestive system as principal agent;
(2), above-mentioned various solid materials are according to a certain weight ratio chopped up respectively, again with the spaced apart container of successively putting into of various different materials, put into an amount of clean clear water submergence raw material and soaked 12-14 hour, after boiling with big fire then and using moderate heat constant temperature to boil one hour, cease fire and filter, its medicinal liquid splendid attire caught on a filter is in another container;
(3), a certain amount of prepared Digestive system added to boil together in the described medicinal liquid be concentrated into a constant volume, and in concentration process, add an amount of propylparaben and an amount of cyclamate and promptly get described Chinese herbal and crude drugs preparations.
In order to utilize the property of medicine of each ancillary drug fully; in above-mentioned steps (2) after cease fire filtering; an amount of clean clear water submergence will be added after filtering residue turns in the former container again; continuation is boiled with reuse moderate heat constant temperature with big fire and was boiled one hour; cease fire then and filter, again filtrate is mixed in the above-mentioned medicinal liquid concentrated with the boiling of principal agent Digestive system.
For further strengthening the remarkable result of preparation of the present invention when treating disease, said preparation preferably is used in combination with the Western medicine with powerful expansion tiny blood vessels, to replenish the weak point of Chinese medicine.
Chinese herbal and crude drugs preparations of the present invention shows that by the clinical effectiveness that is used in combination with Western medicine that can powerful expansion tiny blood vessels it has following advantage:
1, can effectively dissolve and digest compound macromolecular substances such as fat in endovascular embolus, plaque, inflammatory factor and the decomposition blood constituent, cholesterol, saccharide and guaranteed the unimpeded of vessel inner blood, reduce and alleviated the generation of the diseases such as blood vessel infraction, diabetes, hyperlipidemia, coronary heart disease, apoplexy of the hypertension and the heart, brain, kidney, reached the effect for the treatment of both the principal and secondary aspects of a disease.
2, preparation taking convenience of the present invention, mouthfeel is good, and is nontoxic to human body.
3, can bring into play the bonded advantage of Chinese medicine and western medicine fully, and can significantly reduce the use amount (with not taking this preparation and comparing) of Western medicine, and therapeutic effect is more obvious, and can alleviate or eliminate other complication, enhancing human body immunity power significantly.
The specific embodiment
Chinese herbal and crude drugs preparations of the present invention comprises the medicament of being made by Digestive system in the principal agent Herba nepenthis capsule and pharmaceutically acceptable ancillary drug.
For toxic and side effects and further its therapeutic effect of strengthening of effectively overcoming Digestive system, above-mentioned ancillary drug comprises Herba nepenthis, the Radix Ilicis Pubescentis as ministerial drug.
For the immunity of enhancing body, protect each organ, above-mentioned ancillary drug also includes Spica Prunellae as adjuvant drug, very heavy group, Radix Salviae Miltiorrhizae, Radix Codonopsis, Concha Haliotidis and as propylparaben, the cyclamate of additive.
Immunity for further enhancing body protects each organ better, and above-mentioned ancillary drug also includes Rhizoma Chuanxiong, the Fructus Ligustri Lucidi as messenger drug.
Wherein, the weight proportion of each raw material in the per unit consumption for preparing preparation of the present invention is: (is unit with the gram)
Digestive system: 10-120 Herba nepenthis: 3-15 Radix Ilicis Pubescentis: 3-15
Very heavy group of Spica Prunellae: 2-15: 2-15 Radix Salviae Miltiorrhizae: 2-15
Concha Haliotidis: 2-10 Radix Codonopsis 2-15 Rhizoma Chuanxiong 3-9
Fructus Ligustri Lucidi 2-15 propylparaben: an amount of cyclamate: an amount of
The preferred weight proportioning in the per unit consumption for preparing each raw material of preparation of the present invention is: (is unit with the gram)
Digestive system: 50-60 Herba nepenthis: 5-12 Radix Ilicis Pubescentis: 3-12
Very heavy group of Spica Prunellae: 3-10: 4-12 Radix Salviae Miltiorrhizae: 9-15
Concha Haliotidis: 3-10 Radix Codonopsis: 6-15 Rhizoma Chuanxiong 3-9
Fructus Ligustri Lucidi: 3-10 cyclamate: an amount of propylparaben: an amount of
The concrete preparation method of Chinese herbal and crude drugs preparations of the present invention:
Embodiment one: the preparation of (1), principal agent Digestive system: interior Digestive system process fine-structure mesh, 6 layers of gauze, 20 layers of gauze, the 48 layers of multiple times of filtration such as gauze of pig cage capsule that will gather earlier and, after its filtrate boiled with big fire, boiled 15 minutes with little fire, because Digestive system non-refractory, and in last five minutes, put into 2/10000ths be used for the sterilization and the antiseptical propylparaben, stir evenly and make it fully dissolve the Digestive system that promptly gets as principal agent, in boiling point it being packed into then seals in the disinfectant container;
(2), take by weighing raw material by following weight proportion:
Herba nepenthis 200g Radix Ilicis Pubescentis 200g Spica Prunellae 150g
Very heavy group of 150g Radix Salviae Miltiorrhizae 150g Rhizoma Chuanxiong 100g
Concha Haliotidis 100g Radix Codonopsis 100g Fructus Ligustri Lucidi 100g
Above-mentioned various raw materials are chopped up respectively, again every kind of raw material is divided into many parts, then various stock yard is separated and successively put into rustless steel container, putting into proper amount of dry defecates water logging and does not have raw material and soaked 12-14 hour, make above-mentioned each solid medical material fully absorb moisture, as finding the water deficiency in the immersion process, to repeatedly add water to the medical material face, be preferably in before the decoct medicinal herbs and put into the rustless steel grid on the described solid medical material or steamed wheaten foods send frame, to depress the floating medical material of going up the water surface, can prevent also that simultaneously medical material from floating and influence drug effect in boiling process, boil with big fire then and roll, reuse moderate heat constant temperature boiled one hour, adopted 6 layers after the truce respectively, 20 layers, 48 layers of gauze with prepared medical filtration to another container;
(3), the medicinal residues behind the described container inner filtration are turned, be about to the upper strata medical material and be turned to lower floor, lower floor's medical material is translated into the upper strata, add an amount of clean clear water submergence again, continuation is boiled with big fire and is used moderate heat constant temperature to boil one hour, ceases fire then once more medical filtration to the container of described splendid attire filtering liquid medicine;
(4), prepared Digestive system 3000ml is added boil together in the container of above-mentioned splendid attire medicinal liquid concentrated, and add in concentration process last five minutes 4/10000ths propylparaben do sterilization and anticorrosion with and the 8g cyclamate make to increase sweet usefulness, when medicinal liquid is concentrated to about 4000ml, promptly during the consumption of a course of treatment, stop to heat and the vial of crossing with the ethanol sterilizing of in boiling point, it being packed in, add a cover after going into bottle, preserve in the place, cool place the cooling back.
Embodiment two: different is for present embodiment and embodiment one:
1., in step (2), take by weighing each raw material by following weight proportion:
Herba nepenthis 150g Radix Ilicis Pubescentis 150g Spica Prunellae 120g
Very heavy group of 120g Radix Salviae Miltiorrhizae 100g Rhizoma Chuanxiong 100g
Concha Haliotidis 100g Radix Codonopsis 100g Fructus Ligustri Lucidi 100g
2., in step (4), prepared Digestive system 500ml is added boil together in the container of above-mentioned splendid attire medicinal liquid concentrated.
All the other are identical with the step of embodiment one, are not described in detail in this.
Embodiment three: different is for present embodiment and the foregoing description:
1., in step (2), take by weighing each raw material by following weight proportion:
Herba nepenthis 400g Radix Ilicis Pubescentis 500g Spica Prunellae 200g
Very heavy group of 300g Radix Salviae Miltiorrhizae 200g Rhizoma Chuanxiong 200g
Concha Haliotidis 250g Radix Codonopsis 200g Fructus Ligustri Lucidi 200g
2., in step (4), prepared Digestive system 4000ml is added and boil together in the container of above-mentioned splendid attire medicinal liquid and be concentrated to about 5000ml.
All the other are identical with the step of embodiment one, are not described in detail in this.
For confirming dissolving and the digestion power and the safety in utilization thereof of the principal agent Digestive system in the preparation of the present invention, below be the effect and the safety experiment of this Digestive system:
1, the experiment in vitro of the dissolving of Digestive system and digestion power
Adopt os osseum and the cartilage of pig, thinly slice, through flushing, sterilization, putting into device respectively has in the bottle of disinfectant of Digestive system and cold boiled water, through 5 days standing time, take out the moving back of slight shake and observe, the granule that has only the cartilage thin slice and much dissociate out in the bottle of Digestive system is arranged at device, and other installs the granule that just is not separated in several bottles of cold boiled water, illustrates that thus this Digestive system has the ability of stronger dissolving and digestion zooblast and constituent thereof.If the material that constantly is separated in the live body blood circulation will be excreted as refuse along with blood circulation.But because of having very strong immunocompetence, can not digested for the living cells of human body.
2, the acute toxicity testing of rabbit
Carry out Digestive system filling excess of the stomach one kilogram rabbit alive and test, irritate stomach 20ml morning every day, irritate stomach 20ml afternoon, continue one month experiment, the overall process life of observing rabbit is all very normal, does not have the appearance of untoward reaction.Dissected rabbit afterwards again, do not find that any organ was impaired in its body, the toxicity that this Digestive system is described very a little less than, safe in utilization.
For further strengthening the remarkable result of preparation of the present invention when treating disease, said preparation preferably is used in combination with the Western medicine with powerful expansion tiny blood vessels, this moment, the effect of Western medicine was the blood-activating and qi-promoting of expanding in tiny blood vessels and the promotion blood circulation, to replenish the weak point of Chinese medicine.Because Chinese medicine is approximately one hour main action time in human body, and during this period, tiny blood vessels is expanded many more greatly more, the Chinese herbal medicine fluid that is fed just can dissolve and digest the materials such as small embolus, plaque and various inflammatory factors in the blood vessel more better, thereby more effectively the diseases such as blood vessel infraction, diabetes, hyperlipidemia, coronary heart disease, apoplexy of the heart, brain, the kidney of various essential hypertensions and initiation thereof are got well in treatment.But for forbiddings such as ulcer and suckling, anemia of pregnant woman, menstruation women are arranged in the body.
When preparation of the present invention was used in combination with Western medicine, its usage and consumption were as follows:
1, servicing once in the every order of preparation of the present invention morning, afternoon, obey 80ml at every turn, is further to improve its therapeutic effect, preferably just takes after the heating in 15-20 minute in advance.
2, Western medicine is eaten after meal in every day half an hour, and the back that has Western medicine was just drunk preparation of the present invention in 1.5 to 2 hours.
3, the deal that has Western medicine requires pressure drop stage, can decide by at that time concrete condition, and is roughly as follows:
1., beginning had Western medicine and is depressurized to about systolic pressure 140-160mmHg, diastolic pressure 90-100mmHg in several days;
2., when not having uncomfortable situation, increase at every turn and eat a Western medicine, being depressurized to about systolic pressure 120-140mmHg, diastolic pressure 80-90mmHg, is to finish (about 25 days of time) first course of treatment;
3., when not having uncomfortable situation, increase again at every turn and eat a Western medicine, be depressurized to about systolic pressure 110-130mmHg, diastolic pressure 75-85mmHg;
4., when not having uncomfortable situation, increasing has Western medicine again is depressurized to about systolic pressure 100-120mmHg, diastolic pressure 70-80mmHg, is to finish (time also is 25 days) second course of treatment;
5., so cumulative blood pressure lowering that has Western medicine, general blood pressure is not less than 90/60mmHg.
4, the kind that has Western medicine decide according to the concrete state of an illness, as will treating cerebral thrombosis or when blocking, must be with the Western medicine that can make cerebral vasodilators, and available Western medicine has nimodipine, cinnarizine, nifedipine etc.; When treating angina pectoris (myocardial infarction), must be with Western medicine such as the Western medicine that can make coronary artery expansion, available persantin, Propranolol, isosorbidi dinitras, nifedipines; When treating hypertension, depressor such as available above-mentioned two class Western medicine and nifedipine, nicotinic acid, nitrendipine can make whole body vasodilation.
For showing the bonded therapeutic effect of preparation of the present invention and Western medicine, existing operating position with several routine clinical trials is listed below:
Case one, the serious hypertension renal calculus patient that holds concurrently, 70 years old, the women, before 10 years, can not have an operation because of hyperpiesia, has only a complete kidney now, functions of expelling toxin is relatively poor, before taking this medicine, it is 186/90mmHg for a blood pressure length, and blood fat and cholesterol person are than higher, and be often dizzy, heart danger, leg cramp, take two courses of treatment of Chinese herbal and crude drugs preparations of the present invention, it is every morning, respectively obey this preparation of 80ml afternoon, be engaged in every morning simultaneously, afternoon, service once evening and imitate western medicine of depressurization in short-term, when removing examination in hospital after 50 days, blood pressure has dropped to 130/80mmHg, the while blood fat, cholesterol etc. all recover normally, and are relevant dizzy, heart danger, transference cures such as leg cramp, and not recurrence.
Case two, serious patients with coronary heart disease, 71 years old, the male was in the state of hypertension for a long time, and frequent chest pain is repeatedly treated in hospital and all to be failed thoroughly radical cure, and come voltage stabilizing by taking a large amount of depressor every day.Before taking this medicine, its blood pressure is 230/130mmHg, take four courses of treatment of this Chinese herbal medicine, be respectively to obey 80ml in every morning, afternoon, be engaged in every morning, afternoon, evening simultaneously to service once and imitate western medicine of depressurization in short-term, continue to take 100 days after, chest pain disappears, when removing examination in hospital, the mental status is become quite a different person, and blood pressure can maintain about 150/90mmHg now.
Case three, hyperpietic, 56 years old, the man took this medicine preceding often headache, leg cramp, and blood pressure is about 180/95mmHg, and blood fat, cholesterol are all high, repeatedly treat in hospital and all fail thoroughly to effect a radical cure, and need take a large amount of Western medicine every day.After take three courses of treatment of Chinese herbal and crude drugs preparations of the present invention, be respectively to obey 80ml in every morning, afternoon, being engaged in every morning, afternoon, evening simultaneously services once and imitates cerebral vasodilators Western medicine and coronary artery expansion Western medicine in short-term, after continuing to take 75 days, transference cures such as headache, leg cramp, blood pressure is about 135/80mmHg, and it is normal that blood fat and cholesterol recover substantially, the mental status is good, and not recurrence.
Claims (10)
1, a kind of Chinese herbal and crude drugs preparations is characterized in that comprising the medicament of being made by Digestive system in the principal agent Herba nepenthis capsule and pharmaceutically acceptable ancillary drug.
2, Chinese herbal and crude drugs preparations according to claim 1 is characterized in that above-mentioned ancillary drug comprises Herba nepenthis, the Radix Ilicis Pubescentis as ministerial drug.
3, Chinese herbal and crude drugs preparations according to claim 2 is characterized in that above-mentioned ancillary drug also includes Spica Prunellae as adjuvant drug, very heavy group, Radix Salviae Miltiorrhizae, Radix Codonopsis, Concha Haliotidis and as propylparaben, the cyclamate of additive.
4,, it is characterized in that the weight proportion of above-mentioned each raw material in the per unit consumption is: (is unit with the gram) according to claim 1 or 2 or 3 described Chinese herbal and crude drugs preparationses
Digestive system: 10-120 Herba nepenthis: 3-15 Radix Ilicis Pubescentis: 3-15
Very heavy group of Spica Prunellae: 2-15: 2-15 Radix Salviae Miltiorrhizae: 2-15
Concha Haliotidis: 2-10 Radix Codonopsis 2-15 cyclamate: an amount of
Propylparaben: an amount of
5, Chinese herbal and crude drugs preparations according to claim 4 is characterized in that the preferred weight proportioning of above-mentioned each raw material in the per unit consumption is: (is unit with the gram)
Digestive system: 50-60 Herba nepenthis: 5-12 Radix Ilicis Pubescentis: 3-12
Very heavy group of Spica Prunellae: 3-10: 4-12 Radix Salviae Miltiorrhizae: 9-15
Concha Haliotidis: 3-10 cyclamate: an amount of propylparaben: an amount of
Radix Codonopsis: 6-15
6, a kind of preparation method of Chinese herbal and crude drugs preparations according to claim 1 is characterized in that may further comprise the steps:
(1), the preparation of principal agent Digestive system: the interior Digestive system of Herba nepenthis capsule of returning of will gathering earlier removes slag through multiple times of filtration, after its filtrate boiled with big fire, boiled 15 minutes with little fiery constant temperature, and in last five minutes of boiling, put into and be used for sterilization and antiseptical propylparaben in right amount, stir evenly and it is fully dissolved and obtain Digestive system as monarch drug;
(2), above-mentioned various solid materials are according to a certain weight ratio chopped up respectively, again with the spaced apart container of successively putting into of various different materials, put into an amount of clean clear water submergence raw material and soaked 12-14 hour, after boiling with big fire then and using moderate heat constant temperature to boil one hour, cease fire and filter, its medicinal liquid splendid attire caught on a filter is in another container;
(3), a certain amount of prepared Digestive system added to boil together in the described medicinal liquid be concentrated into a constant volume, and in concentration process, add an amount of propylparaben and an amount of cyclamate and promptly get described Chinese herbal and crude drugs preparations.
7, preparation method according to claim 6; after it is characterized in that in above-mentioned steps (2) filtering in ceasing fire; add an amount of clean clear water submergence again after filtering residue in the former container turned; continuation is boiled with reuse moderate heat constant temperature with big fire and was boiled one hour; cease fire then and filter, again filtrate is mixed in the above-mentioned medicinal liquid concentrated with the boiling of principal agent Digestive system.
8, Chinese herbal and crude drugs preparations as claimed in claim 1 cooperates whole body blood vessel or cerebral vasodilators Western medicine to can be applicable in the treatment or prevention of blood vessel infraction of the heart, brain, kidney of essential hypertension and initiation thereof.
9, Chinese herbal and crude drugs preparations as claimed in claim 1 cooperates whole body expansion Western medicine to can be applicable in the treatment or prevention of diabetes, hyperlipidemia, cholesterol.
10, Chinese herbal and crude drugs preparations as claimed in claim 1 cooperates coronary artery or whole body vasodilation Western medicine to can be applicable in the treatment or prevention of coronary heart disease, apoplexy.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104667255A (en) * | 2015-02-15 | 2015-06-03 | 高长庚 | Traditional Chinese medicinal preparation used for treating diabetes mellitus |
| JP2017519763A (en) * | 2014-06-16 | 2017-07-20 | ネプエトゥクス，エルエルシー | Compositions and methods for treating gluten intolerance and disorders resulting therefrom |
| US11701411B2 (en) | 2015-12-16 | 2023-07-18 | Codexis, Inc. | Compositions and methods for treating gluten intolerance and disorders arising therefrom |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1090505A (en) * | 1993-09-28 | 1994-08-10 | 张芳庭 | A kind of anti-senility health agent and preparation method thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017519763A (en) * | 2014-06-16 | 2017-07-20 | ネプエトゥクス，エルエルシー | Compositions and methods for treating gluten intolerance and disorders resulting therefrom |
| US10960059B2 (en) | 2014-06-16 | 2021-03-30 | Codexis, Inc. | Compositions and methods for treating gluten intolerance and disorders arising therefrom |
| JP2021073236A (en) * | 2014-06-16 | 2021-05-13 | ネプエトゥクス，エルエルシー | Composition and method for treating gluten intolerance and disorder arising therefrom |
| US11723960B2 (en) | 2014-06-16 | 2023-08-15 | Codexis, Inc. | Compositions and methods for treating gluten intolerance and disorders arising therefrom |
| JP7369893B2 (en) | 2014-06-16 | 2023-10-27 | コーディクシス， インク． | Compositions and methods for treating gluten intolerance and disorders resulting therefrom |
| CN104667255A (en) * | 2015-02-15 | 2015-06-03 | 高长庚 | Traditional Chinese medicinal preparation used for treating diabetes mellitus |
| US11701411B2 (en) | 2015-12-16 | 2023-07-18 | Codexis, Inc. | Compositions and methods for treating gluten intolerance and disorders arising therefrom |
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