CN101822789B - Hypotensor treating essential hypertension - Google Patents
Hypotensor treating essential hypertension Download PDFInfo
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- CN101822789B CN101822789B CN2010101551179A CN201010155117A CN101822789B CN 101822789 B CN101822789 B CN 101822789B CN 2010101551179 A CN2010101551179 A CN 2010101551179A CN 201010155117 A CN201010155117 A CN 201010155117A CN 101822789 B CN101822789 B CN 101822789B
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Abstract
The invention discloses a hypotensor treating essential hypertension, which comprises the following material by weight percent: 10-20g tall gastrodia tuber, 10-20g gardenia, 15-25ml bamboo sap, 25-35g boiled sea-ear shell, 25-35g boiled nacre, 10-20g gambir plant, 10-15g eucommia bark, 10-20g taxillus twig, 10-15 baical skullcap root, 6-12g red paeony root, 15-25g dragon bones, 15-25g oyster shell, 15-25g agaric, 15-25g cinnabar root poria, 4-8g liquorice, 10-20g bamboo shavings, 10-15g Indian buead, 6-10g raw rhubarb, 6-10g safflower and 10-15g fetid cassia. The invention can tonify Qi, promote blood circulation, soften blood vessels, soothe heart and dredge meridian, therefore can complement kidney energy, improve heart power, extend blood vessels and the like. The invention can eliminate headache, insomnia and heart-throb and completely cure hypertension and avoid recidivation.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, relate to a kind of depressor for the treatment of essential hypertension specifically, belong to technical field of Chinese medicines.
Background technology
Hypertension is a kind of commonly encountered diseases, frequently-occurring disease clinically, be meant one group of clinical symptom grouping that systolic pressure or diastolic pressure raise, be that the human nerve activity is obstructed, the insufficiency of accommodation of blood vessel kinetic system under cerebral cortex that causes and the cortex is so that the arteriotony that the whole body arteriolospasm produces increases.Most hyperpietic only has slight subjective symptoms in early days in hypertension, as headache, dizzy, insomnia with occur fatigue etc. easily.Along with the development of the state of an illness, symptom is obvious gradually, as numbness of the fingers and stiff or symptom such as the nervous sense of nape portion muscular soreness occurs.Hypertension systolic pressure and diastolic pressure often is all high, and fluctuation of blood pressure originally is bigger, easily increases after anxious state of mind or fatigue, removes the cause of disease or rest bleeding from anus pressure energy and reduces to normally.Show that according to statistics China's hypertension had the trend that rises year by year in recent years, accounted for 11.88% of total population.Estimate that thus there are nearly hundred million patients with hypertension in the whole nation, is height with the northern area sickness rate.
For many years, western medical treatment hypertension mainly adopts reserpine, nimodipine, its happy gram doubly, Western medicine such as Herba Apocyni veneti, though the effect of chemical medicine is rapidly, in the blood pressure lowering process fluctuation of blood pressure big, side effect is also big, can only take stopgap measures to effect a permanent cure, and form drug dependence.So Western medicine can only be to have obeyed to fall, fallen and risen, again and again, need take medicine all the life.Facts have proved that traditional Therapeutic Method is difficult to make hypertension to obtain radical cure, not only makes toxic and side effects significantly reduce with Chinese medicine, and all types of cureless hyperpietics are all had significant curative effect.
Summary of the invention
The problem to be solved in the present invention is to provide a kind of depressor of treatment essential hypertension evident in efficacy.
For addressing the above problem, the present invention institute by the following technical solutions:
A kind of depressor for the treatment of essential hypertension, this medicine is made by following materials of weight proportions: Rhizoma Gastrodiae 10～20g; Fructus Gardeniae 10～20g; Succus Bambusae 15～25ml; Concha Haliotidis 25～35g after frying in shallow oil; Concha Margaritifera 25～35g after frying in shallow oil; Ramulus Uncariae Cum Uncis 10～20g; The Cortex Eucommiae 10～15g; Herba Taxilli 10～20g; Radix Scutellariae 10～15g; Radix Paeoniae Rubra 6～12g; Os Draconis 15～25g; Concha Ostreae 15～25g; Polyporus 15～25g; Poria 15～25g; Radix Glycyrrhizae 4～8g; Caulis Bambusae In Taenia 10～20g; Poria 10～15g; Give birth to the 6～10g of army; Flos Carthami 6～10g; Semen Cassiae 10～15g.
Below be further improvement of these options of the present invention:
This medicine is made by following materials of weight proportions: Rhizoma Gastrodiae 10g; Fructus Gardeniae 10g; Succus Bambusae 15ml; Concha Haliotidis 25g after frying in shallow oil; Concha Margaritifera 25g after frying in shallow oil; Ramulus Uncariae Cum Uncis 10g; Cortex Eucommiae 10g; Herba Taxilli 10g; Radix Scutellariae 10g; Radix Paeoniae Rubra 6g; Os Draconis 15g; Concha Ostreae 15g; Polyporus 15g; Poria 15g; Radix Glycyrrhizae 4g; Caulis Bambusae In Taenia 10g; Poria 10g; Give birth to the 6g of army; Flos Carthami 6g; Semen Cassiae 10g.
The another kind of improvement:
This medicine is made by following materials of weight proportions: Rhizoma Gastrodiae 20g; Fructus Gardeniae 20g; Succus Bambusae 25m1; Concha Haliotidis 35g after frying in shallow oil; Concha Margaritifera 35g after frying in shallow oil; Ramulus Uncariae Cum Uncis 20g; Cortex Eucommiae 15g; Herba Taxilli 20g; Radix Scutellariae 15g; Radix Paeoniae Rubra 12g; Os Draconis 25g; Concha Ostreae 25g; Polyporus 25g; Poria 25g; Radix Glycyrrhizae 8g; Caulis Bambusae In Taenia 20g; Poria 15g; Flos Carthami 10g; Semen Cassiae 15g.
The another kind of improvement:
This medicine is made by following materials of weight proportions: Rhizoma Gastrodiae 15g; Fructus Gardeniae 15g; Succus Bambusae 20ml; Concha Haliotidis 30g after frying in shallow oil; Concha Margaritifera 30g after frying in shallow oil; Ramulus Uncariae Cum Uncis 15g; Cortex Eucommiae 15g; Herba Taxilli 15g; Radix Scutellariae 12g; Radix Paeoniae Rubra 10g; Os Draconis 20g; Concha Ostreae 20g; Polyporus 20g; Poria 20g; Radix Glycyrrhizae 6g; Caulis Bambusae In Taenia 15g; Poria 12g; Flos Carthami 8g; Semen Cassiae 12g.
After the present invention made up said medicine, its drug effect had synergism, in the side:
Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Os Draconis, Concha Ostreae have suppressing the hyperactive liver to relieve the wind syndrome, tranquilizing effect, more than four the flavor be our principal agent.
The Concha Haliotidis suppressing the hyperactive liver and subsiding YANG again with Fructus Gardeniae, Radix Scutellariae clearing away heat-fire, disturbs the heat of Liver Channel on unlikely; Herba Taxilli, Cortex Eucommiae nourishing the liver and kidney can make liver-yang be hidden, and be no longer more floating; The Poria tranquilizing the mind is to separate the disease of insomnia and dreamful sleep; The Radix Achyranthis Bidentatae priming is descending, can strengthen invigorating the liver and kidney with Herba Taxilli, Cortex Eucommiae compatibility; The Succus Bambusae removing heat-phlegm goes sputum disease such as be jammed.Os Draconis, Semen Cassiae suppressing the hyperactive liver, YIN nourishing, YANG hyperactivity suppressing, yin fluid astringing nourishes blood; Caulis Bambusae In Taenia, Poria removing heat-phlegm, the arresting convulsion of the cool heart, dissolving lump and resolving mass; Radix Paeoniae Rubra, Flos Carthami clearing heat for calming endogenous wind, blood circulation promoting and blood stasis dispelling, dredge the meridian passage; Bone and muscle strengthening.
According to the pharmacological research in modern age, Ramulus Uncariae Cum Uncis among the we, the Cortex Eucommiae, Herba Taxilli, Radix Scutellariae, Fructus Gardeniae, Radix Achyranthis Bidentatae etc. all have hypotensive effect in various degree, and has the effect of regulating higher nervous activity, so clinically be usually used in treating the early stage or young and middle-aged patient of hypertension, show as that liver-fire rises, the partially high disease person of liver-yang.
The present invention can benefiting QI for activating blood circulation, relaxing muscles and tendons and activating QI and blood in the collateral, vessel softening, the heart soothing and pulse invigorating, can replenish the kidney energy so have, and improves power aroused in interest, and headache, insomnia, cardio palmus shape are effectively eliminated in effects such as expansion vessel softening, thoroughly cure hypertension, stop recurrence.
The present invention has eliminated the simple expander blood pressure lowering of conventional medicament, drug withdrawal bounce-back, the drawback that side effect is big, and improve the human body self immunologic function, and reach treating both the principal and secondary aspects of a disease, without any side effects, the treatment effective percentage reaches more than 87%.
The invention will be further described below in conjunction with embodiment:
The specific embodiment
Embodiment from year January in January, 2008 to 2009, successively carries out clinical treatment to 560 routine hyperpietics, wherein male 396 examples, women 164 examples; 30 years old～80 years old age; The course of disease 6 months～41 years; There was hemorrhagic apoplexy to send out survivor's 58 examples before going to a doctor; Ischemic cerebrovascular is sent out survivor's 53 examples; Electrocardio diagram deficiency myocardial blood supply person 123 examples, above case has long-term or is interrupted clothes depressor history, but fails steady controlling blood pressure all the time to the normal level person, treatment before measurement mediodespidine average, systolic pressure 155mmhg, diastolic pressure 105mmhg; Most of patient all has clinical manifestations such as headache, dizziness to some extent.
Be divided into treatment I, II, III group and matched group at random, every group 140 routine patient, treatment I, II, III group are taken the present invention's treatment and are made comparisons with the matched group that adopts conventional therapy.
Treatment I group adopts following therapeutic scheme: described medicine is made by following materials of weight proportions: Rhizoma Gastrodiae 10g; Fructus Gardeniae 10g; Succus Bambusae 15ml; Concha Haliotidis 25g after frying in shallow oil; Concha Margaritifera 25g after frying in shallow oil; Ramulus Uncariae Cum Uncis 10g; Cortex Eucommiae 10g; Herba Taxilli 10g; Radix Scutellariae 10g; Radix Paeoniae Rubra 6g; Os Draconis 15g; Concha Ostreae 15g; Polyporus 15g; Poria 15g; Radix Glycyrrhizae 4g; Caulis Bambusae In Taenia 10g; Poria 10g; Give birth to the 6g of army; Flos Carthami 6g; Semen Cassiae 10g.
The cold water of above-mentioned raw materials all being put into 2L except that giving birth to army soaked 15 minutes, boil with moderate heat then, again the army of giving birth to is put into pot after boiling, continue with slow fire boiling after 15～25 minutes, leach the about 200mL of medicinal liquid, and then in the medicine pot, add the cold water of 1.5L, boil the back with moderate heat and continue with slow fire boiling after 15～25 minutes, leach the about 150mL of medicinal liquid, with the medicinal liquid mix homogeneously that leaches for twice.Every day, potion divided morning, the preceding decoction being taken warmly of supper.
Treatment II group adopts following therapeutic scheme: described medicine comprises following materials of weight proportions: Rhizoma Gastrodiae 20g; Fructus Gardeniae 20g; Succus Bambusae 25ml; Concha Haliotidis 35g after frying in shallow oil; Concha Margaritifera 35g after frying in shallow oil; Ramulus Uncariae Cum Uncis 20g; Cortex Eucommiae 15g; Herba Taxilli 20g; Radix Scutellariae 15g; Radix Paeoniae Rubra 12g; Os Draconis 25g; Concha Ostreae 25g; Polyporus 25g; Poria 25g; Radix Glycyrrhizae 8g; Caulis Bambusae In Taenia 20g; Poria 15g; Flos Carthami 10g; Semen Cassiae 15g.
The cold water of above-mentioned raw materials all being put into 3L except that giving birth to army soaked 20 minutes, boil with moderate heat then, again the army of giving birth to is put into pot after boiling, continue with slow fire boiling after 25～35 minutes, leach the about 300mL of medicinal liquid, and then in the medicine pot, add the cold water of 2.5L, boil the back with moderate heat and continue with slow fire boiling after 25～35 minutes, leach the about 250mL of medicinal liquid, with the medicinal liquid mix homogeneously that leaches for twice.Every day, potion divided morning, the preceding decoction being taken warmly of supper.
Treatment III group adopts following therapeutic scheme: medicine is made by following materials of weight proportions: Rhizoma Gastrodiae 15g; Fructus Gardeniae 15g; Succus Bambusae 20ml; Concha Haliotidis 30g after frying in shallow oil; Concha Margaritifera 30g after frying in shallow oil; Ramulus Uncariae Cum Uncis 15g; Cortex Eucommiae 15g; Herba Taxilli 15g; Radix Scutellariae 12g; Radix Paeoniae Rubra 10g; Os Draconis 20g; Concha Ostreae 20g; Polyporus 20g; Poria 20g; Radix Glycyrrhizae 6g; Caulis Bambusae In Taenia 15g; Poria 12g; Flos Carthami 8g; Semen Cassiae 12g.
The cold water of above-mentioned raw materials all being put into 2.5L except that giving birth to army soaked 18 minutes, boil with moderate heat then, again the army of giving birth to is put into pot after boiling, continue with slow fire boiling after 20～30 minutes, leach the about 250mL of medicinal liquid, and then in the medicine pot, add the cold water of 2L, boil the back with moderate heat and continue with slow fire boiling after 20～30 minutes, leach the about 200mL of medicinal liquid, with the medicinal liquid mix homogeneously that leaches for twice.Every day, potion divided morning, the preceding decoction being taken warmly of supper.
Matched group adopts traditional therapeutic scheme, regularly takes reserpine, nimodipine, times its happy gram, Western medicine such as Herba Apocyni veneti.
The patient takes Chinese medicine of the present invention treatment time of a course of treatment, follow up a case by regular visits to every day once, comprise symptom, sign improvement situation, untoward reaction, measure blood pressure before and after the treatment respectively, formulate according to the criterion of therapeutical effect that WHO/ISH in 1999 and international hypertension alliance propose, measuring blood pressure＜140/95mmhg be effectively after treatment full 1 course of treatment, and it is invalid not reaching above-mentioned standard person.
Draw through following up a case by regular visits to, after the treatment of a course of treatment, treatment I organizes has 121 routine patient's measuring blood pressures to reach above-mentioned standard among the 140 routine patients, and the clinical symptoms complete obiteration, and 29 routine patient's clinical symptoms are partly improved or do not improved.
Treatment II organizes has 119 routine patient's measuring blood pressures to reach above-mentioned standard among the 140 routine patients, and the clinical symptoms complete obiteration, and 31 routine patient's clinical symptoms are partly improved or do not improved.
Treatment III organizes has 126 routine patient's measuring blood pressures to reach above-mentioned standard among the 140 routine patients, and the clinical symptoms complete obiteration, and 14 routine patient's clinical symptoms are partly improved or do not improved.
There are 89 routine patient's measuring blood pressures to reach above-mentioned standard among the matched group 140 routine patients, and the clinical symptoms complete obiteration, 51 routine patient's clinical symptoms are partly improved or are not improved.
Therefore the therapeutic effect of treatment group obviously is better than matched group, and in three groups of treatment group, treatment III group is the optimum treatment scheme for therapeutic scheme.
All cure the patient again through the observation treatment in 1 year, and none recurrence of the case of healing is treated effective percentage and reached more than 87%.
Model case 1: the Qin, the woman, 76 years old, the retired professor, chest pain 8 years is accompanied dizzy usually, tinnitus, distending pain of the head and eyes, was lived hospital 5 times repeatedly.Each being in hospital all because of angina pectoris attacks with nervous, malaise symptoms such as the heart tires out, breathe hard, weak, uncomfortable in chest, dizzy, insomnia, through repeatedly Electrocardioscopy, all is diagnosed as coronary heart disease, informal dress sorbitrate, nitroglycerine tablets and temporary must the alleviation.Also once obeyed a lot of Chinese medicines and Chinese patent medicine, as: Folium Ginkgo, the heart can relax, FUFANG DANSHEN PIAN, effect are all not obvious.
Come my institute's out-patient treatment on October 12nd, 2008, clinical manifestation: pained, breathe hard, cardiopalmus, weak, uncomfortable in chest, with dizziness, insomnia, light red tongue, thready and weak pulse, blood pressure 170/100mmhg, patient is reluctant to be in hospital, and only requires in the outpatient service treatment by Chinese herbs first visit: the liver-wind expectorant stasis of blood, excessive rising of liver-YANG, take three doses of this medicines, 1 dose/day, be decocted in water for oral dose; Further consultation once more after three days, patient's symptom disappear substantially, give six doses again, after treatment.October 28, come further consultation again, stable disease is told the patient, serve on February, 1 dose/day, be decocted in water for oral dose, to follow up a case by regular visits to 1 year, patient's blood pressure is normal, and ordinary circumstance is fine.
Model case 2: patient Lee X, man, 72 years old, the highly dense X retired worker of factory in Shandong, hypertension history 24 years is taken FUFANG JIANGYA PIAN for a long time, the Nimodipine sustained release sheet, it is unable left limb to occur after cause was got up in one day, facial hemiparalysis, emergency is examined, and haves a medical check-up: blood pressure 170/100mmhg, CT shows cerebral infarction, examine and be apoplexy, hospitalization is after seven days, stable disease, treatment by Chinese herbs is taken in requirement, after taking six doses of this medicines, blood pressure is reduced to 150/90mmhg, logotype two months, patient's blood pressure is steady, can out-of-bed activity.
Model case 3: grandson patient, the man, 68 years old, the highly dense retired professor in Shandong, because of cardiopalmus repeatedly, uncomfortable in chest, with headache, dizzyly examine over 5 years, both made a definite diagnosis hypertensive heart disease, body is looked into BP:168/97mmHg, row Electrocardioscopy: ST-T is inverted, and left ventricular hypertrophy is intended examining being 3 grades of high-risk, coronary heart disease of hypertension.Once used captopril, give the depressor Nifedipine sustained release tablets, care can relax, medicine such as FUFANG DANSHEN DIWAN, effect is not good enough.
Take this medicine, 1 dose/day, be decocted in water for oral dose; Examine after one week: blood pressure is controlled effectively, and the reflexive heart rate that blood pressure lowering simultaneously causes is accelerated also controlled, cardiopalmus, uncomfortable in chest, obviously alleviate with headache, dizziness, continuing medication 2 all symptoms disappears substantially, continue treatment one month, the patient symptom sign disappears, and does not have any untoward reaction.
Claims (2)
1. depressor for the treatment of essential hypertension, it is characterized in that: this medicine is made by following raw material: Rhizoma Gastrodiae 10～20g; Fructus Gardeniae 10～20g; Succus Bambusae 15～25ml; Concha Haliotidis 25～35g after frying in shallow oil; Concha Margaritifera 25～35g after frying in shallow oil; Ramulus Uncariae Cum Uncis 10～20g; The Cortex Eucommiae 10～15g; Herba Taxilli 10～20g; Radix Scutellariae 10～15g; Radix Paeoniae Rubra 6～12g; Os Draconis 15～25g; Concha Ostreae 15～25g; Polyporus 15～25g; Poria 15～25g; Radix Glycyrrhizae 4～8g; Caulis Bambusae In Taenia 10～20g; Poria 10～15g gives birth to the 6～10g of army, Flos Carthami 6～10g, Semen Cassiae 10～15g.
2. a kind of depressor for the treatment of essential hypertension according to claim 1, it is characterized in that: this medicine is made by following raw material: Rhizoma Gastrodiae 10g; Fructus Gardeniae 10g; Succus Bambusae 15ml; Concha Haliotidis 25g after frying in shallow oil; Concha Margaritifera 25g after frying in shallow oil; Ramulus Uncariae Cum Uncis 10g; Cortex Eucommiae 10g; Herba Taxilli 10g; Radix Scutellariae 10g; Radix Paeoniae Rubra 6g; Os Draconis 15g; Concha Ostreae 15g; Polyporus 15g; Poria 15g; Radix Glycyrrhizae 4g; Caulis Bambusae In Taenia 10g; Poria 10g; Give birth to the 6g of army; Flos Carthami 6g; Semen Cassiae 10g.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010101551179A CN101822789B (en) | 2010-04-26 | 2010-04-26 | Hypotensor treating essential hypertension |
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| CN2010101551179A CN101822789B (en) | 2010-04-26 | 2010-04-26 | Hypotensor treating essential hypertension |
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| CN101822789B true CN101822789B (en) | 2011-08-10 |
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Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102698092B (en) * | 2012-06-04 | 2013-12-25 | 张爱霞 | Traditional Chinese medicine composition for treating liver-Yang hyperactivity-type hypertension |
| CN102907520B (en) * | 2012-11-09 | 2013-11-13 | 乐山逸凡农产品开发有限公司 | Green tea health care product for treating insomnia and preparation method thereof |
| CN103055073B (en) * | 2012-12-27 | 2014-04-16 | 安徽丰原药业股份有限公司 | Traditional Chinese medicine composition and preparation method thereof |
| CN103169888A (en) * | 2013-03-27 | 2013-06-26 | 张廷盖 | Traditional Chinese medicine composition for treating hypertension |
| CN104491023A (en) * | 2014-12-24 | 2015-04-08 | 刘保祥 | Liver soothing and heat clearing agent for treating hypertension I stage combined head heaviness symptom and preparation of liver soothing and heat clearing agent |
| CN107362302A (en) * | 2016-05-11 | 2017-11-21 | 蔡保润 | A kind of Chinese medicine for being used to treat hypertension |
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| CN1241611C (en) * | 2002-04-05 | 2006-02-15 | 刘辰 | Medicine for treating hypertension and its preparing process |
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