CN101028406B - Chinese-medicinal decoction for treating difficult menstruation - Google Patents

Chinese-medicinal decoction for treating difficult menstruation Download PDF

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CN101028406B
CN101028406B CN200710065498A CN200710065498A CN101028406B CN 101028406 B CN101028406 B CN 101028406B CN 200710065498 A CN200710065498 A CN 200710065498A CN 200710065498 A CN200710065498 A CN 200710065498A CN 101028406 B CN101028406 B CN 101028406B
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rhizoma
dysmenorrhea
radix
pain
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CN101028406A (en
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Abstract

A Chinese medicine in the form of decoction for treating menalgia is prepared from more than 10 Chinese-medicinal materials including Chinese angelica root, red peony root, cyprus tube, safflower, etc.

Description

A kind of Chinese medicine decoction for the treatment of dysmenorrhea
Technical field
The present invention relates to a kind of Chinese medicine decoction for the treatment of dysmenorrhea, is that a kind of what treat dysmenorrhea is the decoction of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Dysmenorrhea is meant that the women in menstrual period and front and back thereof, lower abdomen or flank pain occur, even pain and waist sacrum, sends out along with menstrual cycle at every turn, and severe patient can be accompanied nausea and vomiting, dripping cold sweat, deadly cold hand and foot, even faints, and brings influence to the work life.Dysmenorrhea is sent out after 15~25 years old and menophania 6 months well in two years, is one of adolescence common sympton.Its sickness rate report differs, and accounts for 42%~90%, and wherein severe pain is through accounting for 18%.Dysmenorrhea belongs to Chinese medicine " abdominal pain during menstruation " category.
Chinese medicine thinks that special physiological environment is relevant before and after generation and the plain body factor of dysmenorrhea and menstrual period, menstrual period.Between non-menstrual period, dash to appoint QI and blood gentle, paathogenic factor can not cause dash appoint, the uterus stasis of blood stagnates or not enough, so pain does not take place.And before and after menstrual period or menstrual period, it is excessive that the sea of blood rushes down by completely being full of, and prosperous QI and blood changes anxious poly-the uterus QI and blood to empty temporarily through the back by arrogant blood, and paathogenic factor is taken the opportunity and done, and makes QI-blood circulation not smooth, and the uterus menses circulate and are obstructed consequently " stagnation of QI and blood may bring about pain "; Or cause that dash to appoint a uterus to lose in moistening foster, " not flourish and pain ".Its mechanism has branch cold, hot, empty, reality is many with excess syndrome.
Western medicine thinks that dysmenorrhea is because the spastic contraction of uterus muscle causes tissue ischemia to cause.Cause the former of uterus muscle spasm because cervical canal is narrow, the excessive retroversioflexion in uterus, the menses circulation is not smooth, and uterine contraction must be strengthened in the uterus could discharge menses, thereby how in the 1st~2 day dysmenorrhea of menstruation, after a large amount of menses were discharged, pain disappeared immediately.In addition.When uterine hypoplasia, deformity etc., uterus muscle produces inharmonious contraction, also can cause dysmenorrhea.And strip off when intrauterine film monoblock, consequently discharge is not smooth, causes spasmodic dysmenorrhea person, is called membranous dysmenorrhea.Sometimes spiritual hypertonicity, hyperesthesia, overwork, catch cold, living habit changes or when health status is bad, all dysmenorrhea can take place.
Modern medicine generally takes analgesic, tranquilizer to conciliate symptomatic treatments such as painful agent, though but immediate pain alleviating, next time is still.Also available hormone suppresses ovulation, but is not inconsistent and women's physiological.Adopt the inhibitor such as the alleviating pains such as acidum clofenamicum, mefenamic acid etc. and indometacin of prostaglandin synthetase in recent years, but certain side effect is arranged.The effect of Chinese medicine primary dysmenorrhea is adhered to taking medicine as if the patient certainly, and treating both the principal and the secondary aspects of a disease at the same time has obtained significant curative effect mostly.Press for development at present and promptly have remarkable analgesic activity and can thoroughly eradicate the specific drug of the Chinese medicine of the cause of disease again, so that extensive use clinically is that extensive patients is removed suffering of illness as dysmenorrhea.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine decoction for the treatment of dysmenorrhea.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
2.5~10 parts of 1.5~6 parts of Rhizoma Corydalis of 2.5~10 parts of Semen Persicaes of Radix Angelicae Sinensis
0.1~2 part of 1.5~6 parts of Oletum Trogopterori of 2.5~10 parts of Fructus Aurantiis of Radix Paeoniae Rubra
0.1~2 part on 1.5~6 parts of Flos Carthamis of 1.5~6 parts of Pericarpium Citri tangerinaes of Rhizoma Chuanxiong
0.1~2 part of 1.5~6 parts of Radix Et Rhizoma Rhei of 1.5~6 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae Viride
The weight proportion of each raw material of optimization formula of the present invention is:
3.0~7.0 parts of 2.5~3.5 parts of Rhizoma Corydalis of 3.0~7.0 parts of Semen Persicaes of Radix Angelicae Sinensis
0.5~1.5 part of 2.5~3.5 parts of Oletum Trogopterori of 3.0~7.0 parts of Fructus Aurantiis of Radix Paeoniae Rubra
0.5~1.5 part on 2.5~3.5 parts of Flos Carthamis of 2.5~3.5 parts of Pericarpium Citri tangerinaes of Rhizoma Chuanxiong
0.5~1.5 part of 2.5~3.5 parts of Radix Et Rhizoma Rhei of 2.5~3.5 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae Viride
The weight proportion of each raw material of optimum formula of the present invention is:
5 parts of 3 parts of Rhizoma Corydalis of 5 parts of Semen Persicaes of Radix Angelicae Sinensis
1 part of 3 parts of Oletum Trogopterori of 5 parts of Fructus Aurantiis of Radix Paeoniae Rubra
1 part on 3 parts of Flos Carthamis of 3 parts of Pericarpium Citri tangerinaes of Rhizoma Chuanxiong
1 part of 3 parts of Radix Et Rhizoma Rhei of 3 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae Viride
Drug action mechanism among the present invention is as follows:
The Radix Angelicae Sinensis nature and flavor are sweet, hot, warm.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation.Can be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea stimulates the menstrual flow, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 553rd page).
Radix Paeoniae Rubra nature and flavor suffering, hardship, flavor are trembled with fear.Return Liver Channel.Has clearing away heat and cooling blood, the effect of eliminating stasis to stop pain.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, traumatic injury, carbuncle skin infection etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 659th page).
Rhizoma Corydalis nature and flavor suffering, hardship, wet.Return liver, spleen channel.Have and invigorate blood circulation, promoting the circulation of QI, analgesic effect.Can treat the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, treating swelling and pain by traumatic injury etc. (Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 680th page).
Rhizoma Chuanxiong nature and flavor suffering, perfume (or spice).Return liver, gallbladder, pericardium channel.Has blood-activating and qi-promoting, the effect of wind-expelling pain-stopping.Can treat menoxenia, amenorrhea dysmenorrhea, difficult labour, lump in the abdomen stomachache, the twinge of the breast side of body, arthralgia due to cold clonic spasm of the muscle, tumbling and swelling, headache due to pathogenic wind-heat, rheumatic arthralgia, skin infection swells and ache, placenta retention, cerebral ischemia, coronary heart disease, angina pectoris, atherosclerosis, hypertension, leukopenia due to the radiotherapy, chemotherapy, juvenile myopia, vitamin e deficiency, flu is dizzy, external plug nose treating malaria disease etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 171st page).
Pericarpium Citri Reticulatae Viride property of medicine hardship.Suffering, temperature.Return liver, gallbladder, stomach warp.Has soothing the liver dispelling the stagnated QI, the effect that removing food stagnancyization stagnates.Can treat side of body rib, breast, gastral cavilty distending pain, nodule in the breast, acute mastitis, hernia, food stagnation , lumps in the chest and abdomen, chronic malaria addiction piece etc.(the 1717th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Persicae property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal , mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Aurantii property of medicine hardship, acid are slightly cold.Return lung, spleen, stomach, large intestine channel.Has the chest stuffiness relieving of regulating the flow of vital energy, the effect of the stagnant removing food stagnancy of row.Can treat the septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen, heavy behind the dysentery, proctoptosis, uterine prolapse etc.(the 2227th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Pericarpium Citri tangerinae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat septum pectorale, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Cyperi property of medicine suffering, sweet, little hardship, flat.Return liver, tri-jiao channel.Has the resolving depression of regulating the flow of vital energy, regulating menstruation, antiabortive effect.Can treat distending pain over the hypochondrium, distending pain of the breast, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, frequent fetal movement etc.(the 2341st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Oletum Trogopterori nature and flavor are salty, sweet, warm.Return liver, spleen channel.The effect of have promoting blood circulation to remove blood stasis, tonneau muscle arteries and veins, hemostasis and pain-relieving, separating insect poison.Can treat that stasis dysmenorrhea, amenorrhea, puerperal abdonimal pain, puerperal ear pillow pain, puerperal are disliked leakage, bleeding hemorrhoids, hemoptysis, stomachache, arthralgia, bronchiectasis, Serpentis, scorpion, Scolopendra sting sting etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 285th page).
Flos Carthami nature and flavor suffering, temperature.GUIXIN, Liver Channel.Has promoting blood circulation to restore menstrual flow, the effect of eliminating stasis to stop pain.Can treat that amenorrhea, lump in the abdomen, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis are had a pain, carbuncle, fall and reach damage etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 604th page).
Radix Et Rhizoma Rhei property of medicine hardship, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, antidotal effect.Can treat the food stagnation constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting: spit blood, spitting of blood, epistaxis is had blood in stool, hematuria; Blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal , lumps in the chest and abdomen, traumatic injury; Pyretic toxicity carbuncle and ulcer, erysipelas is scalded etc.(the 141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Angelicae Sinensis, Radix Paeoniae Rubra and Rhizoma Corydalis; With Rhizoma Chuanxiong, Pericarpium Citri Reticulatae Viride, Semen Persicae, Fructus Aurantii, Pericarpium Citri tangerinae and Rhizoma Cyperi is ministerial drug; With Oletum Trogopterori, Flos Carthami and Radix Et Rhizoma Rhei is adjuvant.All medicines are harmonious, and are total to the tool vital energy regualting and blood circulation-promoting, the effect of stasis-dispelling and pain-killing.The treatment dysmenorrhea has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment dysmenorrhea of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat dysmenorrhea, and the prevention of dysmenorrhea is also had good effect, and the treatment dysmenorrhea has determined curative effect, has no side effect taking convenience, cheap characteristics.
Further specify medicine of the present invention to treatment TREATMENT OF DYSMENORRHOEA effect below by the clinical practice example.
The dysmenorrhea diagnosis basis: 1. menstrual period or before and after row lower abdomen pain, pain and waist sacrum are very then fainted.Be periodical attack.2. good sending out in young maiden.3. get rid of and suffer from abdominal pain due to the pelvic cavity organic disease.(the 363rd page of chief editor's " traditional Chinese medical science disease diagnosis and treatment standard and prescription are selected for use " People's Health Publisher's calendar year 2001 version such as Dai Shen)
Dysmenorrhea efficacy assessment standard: 1. cure: pain disappears, and continuous 3 menstrual cycle are not seen recurrence.2. take a turn for the better: pain relief or pain disappear, but can not keep more than 3 months.3. do not heal: pain is not seen improvement.(the 367th page of chief editor's " traditional Chinese medical science disease diagnosis and treatment standard and prescription are selected for use " People's Health Publisher's calendar year 2001 version such as Dai Shen)
For showing medicine of the present invention, as follows through clinical test results to treatment TREATMENT OF DYSMENORRHOEA effect; Treatment dysmenorrhea patient 38 examples, the age is 12~25 years old.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.Cure 29 examples and account for 76.3%, 6 examples that take a turn for the better account for 15.8%, and more 3 examples do not account for 7.8%, and total effective rate reaches more than 92%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
5 parts of 3 parts of Rhizoma Corydalis of 5 parts of Semen Persicaes of Radix Angelicae Sinensis
1 part of 3 parts of Oletum Trogopterori of 5 parts of Fructus Aurantiis of Radix Paeoniae Rubra
1 part on 3 parts of Flos Carthamis of 3 parts of Pericarpium Citri tangerinaes of Rhizoma Chuanxiong
1 part of 3 parts of Radix Et Rhizoma Rhei of 3 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae Viride
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The dysmenorrhea decoction plastic packaging that the present invention makes is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1. Chinese medicine decoction for the treatment of dysmenorrhea is characterized in that it is made by following raw materials by weight proportions:
2.5~10 parts of 1.5~6 parts of Rhizoma Corydalis of 2.5~10 parts of Semen Persicaes of Radix Angelicae Sinensis
0.1~2 part of 1.5~6 parts of Oletum Trogopterori of 2.5~10 parts of Fructus Aurantiis of Radix Paeoniae Rubra
0.1~2 part on 1.5~6 parts of Flos Carthamis of 1.5~6 parts of Pericarpium Citri tangerinaes of Rhizoma Chuanxiong
0.1~2 part of 1.5~6 parts of Radix Et Rhizoma Rhei of 1.5~6 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae Viride.
2. a kind of Chinese medicine decoction for the treatment of dysmenorrhea according to claim 1, wherein the weight proportion of each crude drug is:
3.0~7.0 parts of 2.5~3.5 parts of Rhizoma Corydalis of 3.0~7.0 parts of Semen Persicaes of Radix Angelicae Sinensis
0.5~1.5 part of 2.5~3.5 parts of Oletum Trogopterori of 3.0~7.0 parts of Fructus Aurantiis of Radix Paeoniae Rubra
0.5~1.5 part on 2.5~3.5 parts of Flos Carthamis of 2.5~3.5 parts of Pericarpium Citri tangerinaes of Rhizoma Chuanxiong
0.5~1.5 part of 2.5~3.5 parts of Radix Et Rhizoma Rhei of 2.5~3.5 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae Viride.
3. a kind of Chinese medicine decoction for the treatment of dysmenorrhea according to claim 1, wherein the weight proportion of each crude drug is:
5 parts of 3 parts of Rhizoma Corydalis of 5 parts of Semen Persicaes of Radix Angelicae Sinensis
1 part of 3 parts of Oletum Trogopterori of 5 parts of Fructus Aurantiis of Radix Paeoniae Rubra
1 part on 3 parts of Flos Carthamis of 3 parts of Pericarpium Citri tangerinaes of Rhizoma Chuanxiong
1 part of 3 parts of Radix Et Rhizoma Rhei of 3 portions of Rhizoma Cyperis of Pericarpium Citri Reticulatae Viride.
CN200710065498A 2007-04-16 2007-04-16 Chinese-medicinal decoction for treating difficult menstruation Expired - Fee Related CN101028406B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102145056A (en) * 2011-01-14 2011-08-10 万福增 Chinese medical composition for treating puerperal women's diseases and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1522756A (en) * 2001-02-22 2004-08-25 王桂琼 Chest bone fracture therapeutic oral medication

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1522756A (en) * 2001-02-22 2004-08-25 王桂琼 Chest bone fracture therapeutic oral medication

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102145056A (en) * 2011-01-14 2011-08-10 万福增 Chinese medical composition for treating puerperal women's diseases and preparation method thereof
CN102145056B (en) * 2011-01-14 2012-09-12 万福增 Chinese medical composition for treating puerperal women's diseases and preparation method thereof

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