CN100571757C - A kind of Chinese medicine decoction for the treatment of dysmenorrhea - Google Patents
A kind of Chinese medicine decoction for the treatment of dysmenorrhea Download PDFInfo
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- CN100571757C CN100571757C CNB2007100654994A CN200710065499A CN100571757C CN 100571757 C CN100571757 C CN 100571757C CN B2007100654994 A CNB2007100654994 A CN B2007100654994A CN 200710065499 A CN200710065499 A CN 200710065499A CN 100571757 C CN100571757 C CN 100571757C
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Abstract
The present invention relates to a kind of Chinese medicine decoction for the treatment of dysmenorrhea, it is to be raw material with 10 Chinese medicine medicines such as Radix Scutellariae, Semen Coicis, Herba Artemisiae Scopariae, Herba Leonuri, Pollen Typhae and Radix Notoginseng.Has removing damp-heat, the effect of blood-activating analgetic.The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine decoction for the treatment of dysmenorrhea.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
Description
Technical field
The present invention relates to a kind of Chinese medicine decoction for the treatment of dysmenorrhea, is that a kind of dysmenorrhea for the treatment of is the Chinese medicine decoction of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Dysmenorrhea is meant that the women in menstrual period and front and back thereof, lower abdomen or flank pain occur, even pain and waist sacrum, sends out along with menstrual cycle at every turn, and severe patient can be accompanied nausea and vomiting, dripping cold sweat, deadly cold hand and foot, even faints, and brings influence to the work life.Dysmenorrhea is sent out after 15～25 years old and menophania 6 months well in two years, is one of adolescence common sympton.Its sickness rate report differs, and accounts for 42%～90%, and wherein severe pain is through accounting for 18%.Dysmenorrhea belongs to Chinese medicine " abdominal pain during menstruation " category.
Chinese medicine thinks that special physiological environment is relevant before and after generation and the plain body factor of dysmenorrhea and menstrual period, menstrual period.Between non-menstrual period, dash to appoint QI and blood gentle, paathogenic factor can not cause dash appoint, the uterus stasis of blood stagnates or not enough, so pain does not take place.And before and after menstrual period or menstrual period, it is excessive that the sea of blood rushes down by completely being full of, and prosperous QI and blood changes anxious poly-the uterus QI and blood to empty temporarily through the back by arrogant blood, and paathogenic factor is taken the opportunity and done, and makes QI-blood circulation not smooth, and the uterus menses circulate and are obstructed consequently " stagnation of QI and blood may bring about pain "; Or cause that dash to appoint a uterus to lose in moistening foster, " not flourish and pain ".Its mechanism has branch cold, hot, empty, reality is many with excess syndrome.
Western medicine thinks that dysmenorrhea is because the spastic contraction of uterus muscle causes tissue ischemia to cause.Cause the former of uterus muscle spasm because cervical canal is narrow, the excessive retroversioflexion in uterus, the menses circulation is not smooth, and uterine contraction must be strengthened in the uterus could discharge menses, thereby how in the 1st～2 day dysmenorrhea of menstruation, after a large amount of menses were discharged, pain disappeared immediately.In addition.When uterine hypoplasia, deformity etc., uterus muscle produces inharmonious contraction, also can cause dysmenorrhea.And strip off when intrauterine film monoblock, consequently discharge is not smooth, causes spasmodic dysmenorrhea person, is called membranous dysmenorrhea.Sometimes spiritual hypertonicity, hyperesthesia, overwork, catch cold, living habit changes or when health status is bad, all dysmenorrhea can take place.
Modern medicine generally takes analgesic, tranquilizer to conciliate symptomatic treatments such as painful agent, though but immediate pain alleviating, next time is still.Also available hormone suppresses ovulation, but is not inconsistent and women's physiological.Adopt the inhibitor such as the alleviating pains such as acidum clofenamicum, mefenamic acid etc. and indometacin of prostaglandin synthetase in recent years, but certain side effect is arranged.The effect of Chinese medicine primary dysmenorrhea is adhered to taking medicine as if the patient certainly, and treating both the principal and the secondary aspects of a disease at the same time has obtained significant curative effect mostly.Right this patient does not generally have significant discomfort at ordinary times, and the several months takes Chinese medicine decoction and is difficult to adhere to more, and is agonizing again during outbreak, so that menstrual onset is produced fear, and the hypertonicity of spirit has increased the weight of the degree of pain.Press for development at present and promptly have remarkable analgesic activity and can thoroughly eradicate the specific drug of the Chinese medicine of the cause of disease again, so that extensive use clinically is that extensive patients is removed suffering of illness as dysmenorrhea.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine decoction for the treatment of dysmenorrhea.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5～6 parts of 2.5～10 parts of Rhizoma Corydalis of 2.5～10 parts of Semen Coiciss of Radix Scutellariae
1.5～6 parts of 1.5～6 parts of Herba Leonuris of 2.5～10 parts of Fructus Crataegi of Herba Artemisiae Scopariae
0.1～2 part of 1.5～6 parts of Pollen Typhae of 1.5～6 parts of Cortex Moutans of Radix Paeoniae Rubra
0.1～2 part of 0.1～2 part of Oletum Trogopterori of 1.5～6 portions of Radix Notoginseng of Radix Salviae Miltiorrhizae
The weight proportion of each raw material of optimization formula of the present invention is:
2.5～3.5 parts of 3.0～7.0 parts of Rhizoma Corydalis of 3.0～7.0 parts of Semen Coiciss of Radix Scutellariae
2.5～3.5 parts of 2.5～3.5 parts of Herba Leonuris of 3.0～7.0 parts of Fructus Crataegi of Herba Artemisiae Scopariae
0.5～1.5 part of 2.5～3.5 parts of Pollen Typhae of 2.5～3.5 parts of Cortex Moutans of Radix Paeoniae Rubra
0.5～1.5 part of 0.5～1.5 part of Oletum Trogopterori of 2.5～3.5 portions of Radix Notoginseng of Radix Salviae Miltiorrhizae
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 5 parts of Rhizoma Corydalis of 5 parts of Semen Coiciss of Radix Scutellariae
3 parts of 3 parts of Herba Leonuris of 5 parts of Fructus Crataegi of Herba Artemisiae Scopariae
1 part of 3 parts of Pollen Typhae of 3 parts of Cortex Moutans of Radix Paeoniae Rubra
1 part of 1 part of Oletum Trogopterori of 3 portions of Radix Notoginseng of Radix Salviae Miltiorrhizae
Drug action mechanism among the present invention is as follows:
Radix Scutellariae property of medicine hardship, cold.Return lung, the heart, liver, gallbladder, large intestine channel.Has clearing away heat-fire, dampness detoxifcation, hemostasis, antiabortive effect.Can treat the cough due to lung-heat, the calentura unconsciousness due to high fever, the liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria is told nosebleed, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle etc.(the 2808th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Artemisiae Scopariae nature and flavor hardship, suffering are slightly cold.Return spleen, stomach, liver, gallbladder meridian.Has clearing away damp-heat, the effect of jaundice eliminating subcutaneous ulcer.Can treat the jaundice oliguria, the eczema pruritus; Infectious jaundice type hepatitis etc.(the 192nd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Semen Coicis nature and flavor are sweet, light, cool.Return spleen, stomach, lung meridian.Has the spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, the effect of clearing away heat and discharging pus.Can treat edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana etc.(the 309th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Radix Paeoniae Rubra nature and flavor suffering, hardship, flavor are trembled with fear.Return Liver Channel.Has clearing away heat and cooling blood, the effect of eliminating stasis to stop pain.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, traumatic injury, carbuncle skin infection etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 659th page).
Rhizoma Corydalis nature and flavor suffering, hardship, wet.Return liver, spleen channel.Have and invigorate blood circulation, promoting the circulation of QI, analgesic effect.Can treat the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, treating swelling and pain by traumatic injury etc. (Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 680th page).
Fructus Crataegi property of medicine acid, sweet, tepor.Return spleen, stomach, Liver Channel.Has promoting digestion and invigorating the stomach, the effect of circulation of qi promoting dissipating blood stasis.Can treat eating accumulation, abdominal distention, diarrhea dysentery, amenorrhea, puerperal abdonimal pain, lochiorrhea, hernia or painful and swollen testis, hyperlipidemia etc.(the 226th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Salviae Miltiorrhizae nature and flavor hardship is slightly cold.GUIXIN, Liver Channel.Has stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire.Can treat menoxenia, amenorrhea dysmenorrhea ， lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris etc.(the 57th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Leonuri nature and flavor hardship, suffering, be slightly cold.Return liver, pericardium channel.Effect with regulating menstruation and activating blood, promoting tissue regeneration by removing blood stasis, inducing diuresis to remove edema.Can treat menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, have blood in stool, carbuncle skin infection etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1050th page).
Sweet, the little suffering of the Pollen Typhae property of medicine, flat.Return liver, the heart, spleen channel.Has hemostasis, blood stasis dispelling, diuretic effect.Can treat haematemesis, spitting of blood, epistaxis, dysentery is had blood in stool, metrorrhagia, traumatic hemorrhage, trusted subordinate's pain, amenorrhea stomachache, puerperal stasis of blood pain, dysmenorrhea, tumbling and swelling, blood strangury and dry pain, leukorrhagia, congenital deformity of the tongue, aphtha, uncontrolled urination is itched etc.(the 3423rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of Radix Notoginseng nature and flavor, temperature.Return liver, stomach warp.Has the dissipating blood stasis hemostasis, the effect of subduing swelling and relieving pain.Can treat spitting of blood, spit blood, have blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling etc.(the 10th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Oletum Trogopterori nature and flavor are salty, sweet, warm.Return liver, spleen channel.The effect of have promoting blood circulation to remove blood stasis, tonneau muscle arteries and veins, hemostasis and pain-relieving, separating insect poison.Can treat that stasis dysmenorrhea, amenorrhea, puerperal abdonimal pain, puerperal ear pillow pain, puerperal are disliked leakage, bleeding hemorrhoids, hemoptysis, stomachache, arthralgia, bronchiectasis, Serpentis, scorpion, Scolopendra sting sting etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 285th page).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Scutellariae, Herba Artemisiae Scopariae and Semen Coicis; With Radix Paeoniae Rubra, Rhizoma Corydalis, Fructus Crataegi, Radix Salviae Miltiorrhizae, Cortex Moutan and Herba Leonuri is ministerial drug; With Pollen Typhae, Radix Notoginseng and Oletum Trogopterori is adjuvant.All medicines are harmonious, and are total to the tool removing damp-heat, the effect of blood-activating analgetic.The treatment dysmenorrhea has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment dysmenorrhea of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat dysmenorrhea, and the prevention of dysmenorrhea is also had good effect, and the treatment dysmenorrhea has determined curative effect, has no side effect taking convenience, cheap characteristics.
Further specify medicine of the present invention to treatment TREATMENT OF DYSMENORRHOEA effect below by the clinical practice example.
The dysmenorrhea diagnosis basis: 1. menstrual period or before and after row lower abdomen pain, pain and waist sacrum are very then fainted.Be periodical attack.2. good sending out in young maiden.3. get rid of and suffer from abdominal pain due to the pelvic cavity organic disease.(the 363rd page of chief editor's " traditional Chinese medical science disease diagnosis and treatment standard and prescription are selected for use " People's Health Publisher's calendar year 2001 version such as Dai Shen)
Dysmenorrhea efficacy assessment standard: 1. cure: pain disappears, and continuous 3 menstrual cycle are not seen recurrence.2. take a turn for the better: pain relief or pain disappear, but can not keep more than 3 months.3. do not heal: pain is not seen improvement.(the 367th page of chief editor's " traditional Chinese medical science disease diagnosis and treatment standard and prescription are selected for use " People's Health Publisher's calendar year 2001 version such as Dai Shen)
For showing medicine of the present invention, as follows through clinical test results to treatment TREATMENT OF DYSMENORRHOEA effect; Treatment dysmenorrhea patient 56 examples, the age is 12～25 years old.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.Cure 44 examples and account for 78.57%, 9 examples that take a turn for the better account for 16.07%, and more 3 examples do not account for 5.37%, and total effective rate reaches more than 94%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 5 parts of Rhizoma Corydalis of 5 parts of Semen Coiciss of Radix Scutellariae
3 parts of 3 parts of Herba Leonuris of 5 parts of Fructus Crataegi of Herba Artemisiae Scopariae
1 part of 3 parts of Pollen Typhae of 3 parts of Cortex Moutans of Radix Paeoniae Rubra
1 part of 1 part of Oletum Trogopterori of 3 portions of Radix Notoginseng of Radix Salviae Miltiorrhizae
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The dysmenorrhea decoction plastic packaging that the present invention makes is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.
Claims (3)
1, a kind of Chinese medicine decoction for the treatment of dysmenorrhea is characterized in that it is made by following raw materials by weight proportions:
1.5～6 parts of 2.5～10 parts of Rhizoma Corydalis of 2.5～10 parts of Semen Coiciss of Radix Scutellariae
1.5～6 parts of 1.5～6 parts of Herba Leonuris of 2.5～10 parts of Fructus Crataegi of Herba Artemisiae Scopariae
0.1～2 part of 1.5～6 parts of Pollen Typhae of 1.5～6 parts of Cortex Moutans of Radix Paeoniae Rubra
0.1～2 part of 0.1～2 part of Oletum Trogopterori of 1.5～6 portions of Radix Notoginseng of Radix Salviae Miltiorrhizae.
2, a kind of Chinese medicine decoction for the treatment of dysmenorrhea according to claim 1, wherein the weight proportion of each crude drug is:
2.5～3.5 parts of 3.0～7.0 parts of Rhizoma Corydalis of 3.0～7.0 parts of Semen Coiciss of Radix Scutellariae
2.5～3.5 parts of 2.5～3.5 parts of Herba Leonuris of 3.0～7.0 parts of Fructus Crataegi of Herba Artemisiae Scopariae
0.5～1.5 part of 2.5～3.5 parts of Pollen Typhae of 2.5～3.5 parts of Cortex Moutans of Radix Paeoniae Rubra
0.5～1.5 part of 0.5～1.5 part of Oletum Trogopterori of 2.5～3.5 portions of Radix Notoginseng of Radix Salviae Miltiorrhizae.
3, a kind of Chinese medicine decoction for the treatment of dysmenorrhea according to claim 1, wherein the weight proportion of each crude drug is:
3 parts of 5 parts of Rhizoma Corydalis of 5 parts of Semen Coiciss of Radix Scutellariae
3 parts of 3 parts of Herba Leonuris of 5 parts of Fructus Crataegi of Herba Artemisiae Scopariae
1 part of 3 parts of Pollen Typhae of 3 parts of Cortex Moutans of Radix Paeoniae Rubra
1 part of 1 part of Oletum Trogopterori of 3 portions of Radix Notoginseng of Radix Salviae Miltiorrhizae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2007100654994A CN100571757C (en) | 2007-04-16 | 2007-04-16 | A kind of Chinese medicine decoction for the treatment of dysmenorrhea |
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| CNB2007100654994A CN100571757C (en) | 2007-04-16 | 2007-04-16 | A kind of Chinese medicine decoction for the treatment of dysmenorrhea |
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| CN101028465A CN101028465A (en) | 2007-09-05 |
| CN100571757C true CN100571757C (en) | 2009-12-23 |
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| CNB2007100654994A Expired - Fee Related CN100571757C (en) | 2007-04-16 | 2007-04-16 | A kind of Chinese medicine decoction for the treatment of dysmenorrhea |
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| CN104510853B (en) * | 2014-12-16 | 2015-10-28 | 山东京御堂国药有限公司 | A kind of Chinese medicinal effective-part composition for the treatment of dysmenorrhes and uses thereof |
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Non-Patent Citations (2)
| Title |
|---|
| 原发性痛经中医治疗进展. 于建华，李乃荣，袁绿化.中国中医急症，第13卷第8期. 2004 |
| 原发性痛经中医治疗进展. 于建华，李乃荣，袁绿化.中国中医急症，第13卷第8期. 2004 * |
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