CN101112599A - Chinese patent drug for treating chloasma - Google Patents
Chinese patent drug for treating chloasma Download PDFInfo
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- CN101112599A CN101112599A CNA2007101209688A CN200710120968A CN101112599A CN 101112599 A CN101112599 A CN 101112599A CN A2007101209688 A CNA2007101209688 A CN A2007101209688A CN 200710120968 A CN200710120968 A CN 200710120968A CN 101112599 A CN101112599 A CN 101112599A
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Abstract
The present invention relates to a Chinese traditional patent medicine for treating chloasma, which takes more than 10 traditional Chinese medicines of Chinese thorowax root, Chinese angelica, red paeony root, salvia miltiorrhiza, radix rehmanniae glutinosae etc. as the raw materials. The present invention has the effects of soothing liver, anti-depression and regulating qi and activating blood circulation. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results with the traditional Chinese medicine. The present invention aims at providing the Chinese traditional patent medicine to treat chloasma. The present invention is characterized by accurate efficacy, safety, convenience, no toxicity or side effects and low price.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of chloasma, is that a kind of chloasma for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Chloasma is that a kind of common face that the increase owing to dermal melanin forms is brown or melanin pigmentation, decreases the dermatosis of capacitive.Chloasma reaches 9.7% in some areas crowd nature prevalence, and female patient is about 9: 1 with male patient's ratio, and more up to 28.2%, it is ill more especially to organize the women at reproduction age among the adult female.Chloasma is among the people to be commonly called as " chloasma hepaticum ", " black speck ", " butterfly spot ".Primary disease is mainly in the women of anemia of pregnant woman or menoxenia simultaneously.Claim again " cyasma ", belong to " black Shao-", the category of " dusty face " of Chinese medicine.The traditional Chinese medical science just has exopathogen to invade the shaoyang channel arteries and veins in " Ling Shu Miraculous Pivot or Divine Axis passages through which vital energy circulates " to the record of chloasma, can make " sick bitter taste, very then face has micronic dust "; Invade the meridian of Foot-JUE YIN arteries and veins, also can get saying of " dusty face "." all source of disease marquis's opinion dark complexion Shao-marquis " discussed the cause of disease of chloasma from aspects such as internal organs, QI and blood, phlegm-damp, exopathogen, think that " vital organs of the human body 12 menses are all gone up in face.The all flourish the exterior and the interior of husband's blood trip, people or phlegm retention stain is dirty, or the space between skin and muscles wind-engaging, to disharmony between QI and blood, puckery or turbid can not be flourish in skin, so Shao-takes place to deceive ".Point out in " Waike Zhengzong, Orthodox Manual of External Diseases volume four ": " the chloasma person, water thanks to can not be made fire, can not magnificent meat a little less than the blood, so that fiery dryness accumulated in the stomach and intestine becomes speckle black, and color is withered not damp." " Yizong Jinjian surgery heart method knack rolls up 63 " add: " it is depressed to be worried, not magnificent a little less than the blood, and fiery dryness accumulated in the stomach and intestine stagnates and is born on the face, and the women has it more." " surgery card control pandect " think this disease " depressed by being worried, not magnificent a little less than the blood " and cause.Primary disease is dirty relevant with liver spleen kidney three, demonstrate,proves many deficiency and excesss and holds under the arm assortedly, but its total etiology and pathogenesis is blood deficiency, blood stasis.The traditional Chinese medical science divides clinically that stagnation of liver-QI with deficiency of the spleen, qi depression to blood stasis, blood-deficiency leading to hyperactivity of the liver, deficiency of kidney-YIN, damp invasion of lower energizer, stagnation of QI due to depression of the liver, insufficiency of the spleen blood are weak, stop in the disharmony of Chong and Conception Channels, phlegm-damp, kidney yin sun two loses the disease type Coryza Treated by Syndrome Differentiation such as blood stasis, cold and stagnate of holding concurrently, and obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese patent medicine for the treatment of chloasma.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
1.0～4 parts of 1.5～6 parts of Herba Leonuris of 1.5～6 parts of Pericarpium Citri Reticulataes of Radix Salviae Miltiorrhizae
1.0～4 parts of 1.0～4 parts of Radix Polygoni Multiflori of 1.0～4 parts of Radix Angelicae Sinensis of Radix Bupleuri
1.0～4 parts of 1.0～4 parts of Radix Rehmanniae of 1.0～4 parts of Poria of Radix Paeoniae Rubra
0.1～2 part of 0.1～2 part of Fructus Gardeniae (parched) of 0.1～2 part of Rhizoma Chuanxiong of Radix Curcumae.
The weight proportion of each crude drug of optimization formula of the present invention is:
1.5～2.5 parts of 2.5～3.5 parts of Herba Leonuris of 2.5～3.5 parts of Pericarpium Citri Reticulataes of Radix Salviae Miltiorrhizae
1.5～2.5 parts of 1.5～2.5 parts of Radix Polygoni Multiflori of 1.5～2.5 parts of Radix Angelicae Sinensis of Radix Bupleuri
1.5～2.5 parts of 1.5～2.5 parts of Radix Rehmanniae of 1.5～2.5 parts of Poria of Radix Paeoniae Rubra
0.5～1.5 part of 0.5～1.5 part of Fructus Gardeniae (parched) of 0.5～1.5 part of Rhizoma Chuanxiong of Radix Curcumae.
The weight proportion of each crude drug of optimum formula of the present invention is:
2 parts of 3 parts of Herba Leonuris of 3 parts of Pericarpium Citri Reticulataes of Radix Salviae Miltiorrhizae
2 parts of 2 parts of Radix Polygoni Multiflori of 2 parts of Radix Angelicae Sinensis of Radix Bupleuri
2 parts of 2 parts of Radix Rehmanniae of 2 parts of Poria of Radix Paeoniae Rubra
1 part of 1 part of Fructus Gardeniae (parched) of 1 part of Rhizoma Chuanxiong of Radix Curcumae.
Drug action mechanism among the present invention is as follows:
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, the addiction abdominal mass is gathered, and pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Leonuri property of medicine suffering, hardship are slightly cold.Return liver, kidney, pericardium channel.Has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection etc.(the 2697th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Polygoni Multiflori property of medicine hardship, sweet, puckery, tepor.Return liver, the heart, kidney channel.Have nourishing the blood and yin, loosening bowel to relieve constipation dispels the wind, the antidotal effect.Can treat Light-headedness, cardiopalmus, insomnia, soreness of the waist and knees, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body void, rubella pruritus, carbuncle sore, scrofula, hemorrhoid etc.(the 1588th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Radix Curcumae property of medicine suffering, hardship, cold.GUIXIN, liver, gallbladder meridian.Has promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, the effect of function of gallbladder promoting.Can treat all pains of breast abdomen side of body rib, dysmenorrhea ， mass in the abdomen, the calentura coma, demented, spit blood epistaxis, stranguria with blood, sand Stranguria, jaundice etc.(the 1855th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, addiction abdominal mass lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Gardeniae (parched) property of medicine hardship, cold.GUIXIN, liver, lung, stomach, tri-jiao channel.Has the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the effect of removing pathogenic heat from blood and toxic substance from the body.It is vexed to treat calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue, sore swollen toxin is sprained and is swollen and ache etc.(the 2242nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Bupleuri, Radix Salviae Miltiorrhizae and Pericarpium Citri Reticulatae; With Radix Angelicae Sinensis, Radix Paeoniae Rubra, Poria, Herba Leonuri, Radix Polygoni Multiflori and Radix Rehmanniae is ministerial drug; With Radix Curcumae, Fructus Gardeniae (parched) and Rhizoma Chuanxiong is adjuvant.All medicines are harmonious, and are total to the tool soothing liver-QI for relieving depression, the effect of vital energy regualting and blood circulation-promoting.The treatment chloasma has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment chloasma of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat chloasma, and the prevention of chloasma is also had good effect, and the treatment chloasma has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment chloasma; Treatment patient with chloasma 47 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.34 examples of fully recovering account for 77.19%, and 9 examples that take a turn for the better account for 15.79%, and more 4 examples do not account for 7%, and total effective rate reaches 93%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction is pressed following weight weighting raw materials:
2 parts of 3 parts of Herba Leonuris of 3 parts of Pericarpium Citri Reticulataes of Radix Salviae Miltiorrhizae
2 parts of 2 parts of Radix Polygoni Multiflori of 2 parts of Radix Angelicae Sinensis of Radix Bupleuri
2 parts of 2 parts of Radix Rehmanniae of 2 parts of Poria of Radix Paeoniae Rubra
1 part of 1 part of Fructus Gardeniae (parched) of 1 part of Rhizoma Chuanxiong of Radix Curcumae.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment chloasma that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.
Claims (3)
1. Chinese patent medicine for the treatment of chloasma is characterized in that it is made by following raw materials by weight proportions:
1.0～4 parts of 1.5～6 parts of Herba Leonuris of 1.5～6 parts of Pericarpium Citri Reticulataes of Radix Salviae Miltiorrhizae
1.0～4 parts of 1.0～4 parts of Radix Polygoni Multiflori of 1.0～4 parts of Radix Angelicae Sinensis of Radix Bupleuri
1.0～4 parts of 1.0～4 parts of Radix Rehmanniae of 1.0～4 parts of Poria of Radix Paeoniae Rubra
0.1～2 part of 0.1～2 part of Fructus Gardeniae (parched) of 0.1～2 part of Rhizoma Chuanxiong of Radix Curcumae.
2. a kind of Chinese patent medicine for the treatment of chloasma according to claim 1, wherein the weight proportion of each crude drug is:
1.5～2.5 parts of 2.5～3.5 parts of Herba Leonuris of 2.5～3.5 parts of Pericarpium Citri Reticulataes of Radix Salviae Miltiorrhizae
1.5～2.5 parts of 1.5～2.5 parts of Radix Polygoni Multiflori of 1.5～2.5 parts of Radix Angelicae Sinensis of Radix Bupleuri
1.5～2.5 parts of 1.5～2.5 parts of Radix Rehmanniae of 1.5～2.5 parts of Poria of Radix Paeoniae Rubra
0.5～1.5 part of 0.5～1.5 part of Fructus Gardeniae (parched) of 0.5～1.5 part of Rhizoma Chuanxiong of Radix Curcumae.
3. a kind of Chinese patent medicine for the treatment of chloasma according to claim 1, wherein the weight proportion of each crude drug is:
2 parts of 3 parts of Herba Leonuris of 3 parts of Pericarpium Citri Reticulataes of Radix Salviae Miltiorrhizae
2 parts of 2 parts of Radix Polygoni Multiflori of 2 parts of Radix Angelicae Sinensis of Radix Bupleuri
2 parts of 2 parts of Radix Rehmanniae of 2 parts of Poria of Radix Paeoniae Rubra
1 part of 1 part of Fructus Gardeniae (parched) of 1 part of Rhizoma Chuanxiong of Radix Curcumae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101209688A CN101112599A (en) | 2007-08-29 | 2007-08-29 | Chinese patent drug for treating chloasma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101209688A CN101112599A (en) | 2007-08-29 | 2007-08-29 | Chinese patent drug for treating chloasma |
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| CN101112599A true CN101112599A (en) | 2008-01-30 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101209688A Pending CN101112599A (en) | 2007-08-29 | 2007-08-29 | Chinese patent drug for treating chloasma |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258439A (en) * | 2010-12-21 | 2011-11-30 | 祝凤仪 | Formula of spot-removing facemask for treating pigmented spots and preparation method thereof |
| CN105362956A (en) * | 2015-12-18 | 2016-03-02 | 杜小卫 | Traditional Chinese medicine compound capable of removing chloasma and beautifying faces |
| CN108578669A (en) * | 2018-08-08 | 2018-09-28 | 陕西惠福药业有限公司 | Cool blood spot-removing pill |
-
2007
- 2007-08-29 CN CNA2007101209688A patent/CN101112599A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258439A (en) * | 2010-12-21 | 2011-11-30 | 祝凤仪 | Formula of spot-removing facemask for treating pigmented spots and preparation method thereof |
| CN102258439B (en) * | 2010-12-21 | 2012-07-04 | 祝凤仪 | Formula of spot-removing facemask for treating pigmented spots and preparation method thereof |
| CN105362956A (en) * | 2015-12-18 | 2016-03-02 | 杜小卫 | Traditional Chinese medicine compound capable of removing chloasma and beautifying faces |
| CN108578669A (en) * | 2018-08-08 | 2018-09-28 | 陕西惠福药业有限公司 | Cool blood spot-removing pill |
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Open date: 20080130 |