CN101112550A - Chinese patent drug for treating amenorrhea-lactorrhea lactorrhea - Google Patents
Chinese patent drug for treating amenorrhea-lactorrhea lactorrhea Download PDFInfo
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- CN101112550A CN101112550A CNA2007101209851A CN200710120985A CN101112550A CN 101112550 A CN101112550 A CN 101112550A CN A2007101209851 A CNA2007101209851 A CN A2007101209851A CN 200710120985 A CN200710120985 A CN 200710120985A CN 101112550 A CN101112550 A CN 101112550A
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Abstract
The present invention relates to a Chinese traditional patent medicine for treating amenorrhea-galactorrhea syndrome, which takes more than 10 Chinese herbal medicines of fried malt, medicinal cyathula root, motherwort herb, safflower etc. as the raw materials. The present invention has the effects of soothing liver, regulating qi, activating blood circulation and regulating menstruation. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results with the traditional Chinese medicine. The present invention aims at providing the Chinese traditional patent medicine for treating amenorrhea-galactorrhea syndrome. The present invention is characterized by accurate efficacy, safety, convenience, no toxicity or side effects and low price.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of amenorrhea-galactorrhea syndrome, is that a kind of amenorrhea-galactorrhea syndrome for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Amenorrhea-galactorrhea syndrome (Amenorrhea-galacforrhea syndrome, be called for short A-G syndrome) be non-puerperal the women or the puerpera stopping suckling after 1 year, the persistence galactorrhea appears, and with amenorrhea.Most patients merges hyperprolactinemia, and the A-G syndrome comprises the Chiari-Frommel syndrome, amenorrhea and galactorrhea phenomenon promptly occur childbirth and post-abortion; Ahumada-del Castillo syndrome, i.e. amenorrhea, galactorrhea not necessarily betide puerperal or post-abortion, and whenever irrelevant can betide gestation, and the Forbes-Albright syndrome, i.e. amenorrhea, galactorrhea may be relevant with pituitary tumor.Along with the development of various clinical examinations and lab testing means, disclose the common pathological characteristic that above three kinds of situations all have hypothalamus-pituitary function imbalance.Therefore, be referred to as " A-G syndrome " at present.Belong to Chinese medicine " the milk dripping spontaneously ", " amenorrhea " and " menoxenia " category.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as irritability stasis, stagnated heat of liver channel, caused by liver and kidney deficiency, insufficiency of the spleen stagnation of phlegm clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese patent medicine for the treatment of amenorrhea-galactorrhea syndrome.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
0.1～2 part of 1.0～4 portions of Rhizoma Alismatis of 1.5～6 portions of Rhizoma Cyperis of Fructus Hordei Germinatus (parched)
0.1～2 part of 1.0～4 parts of Radix Bupleuri of 1.0～4 parts of Pericarpium Citri Reticulataes of Herba Leonuri
0.1～2 part of 1. 0～4 parts of Rhizoma Chuanxiong of 1.0～4 parts of Fructus Aurantiis of Radix Rehmanniae Preparata
0.1～2 part of 0.1～2 part of Radix Angelicae Sinensis of 0.1～2 part of Flos Carthami of Radix Cyathulae.
The weight proportion of each crude drug of optimization formula of the present invention is:
0.5～1.5 part of 1.5～2.5 portions of Rhizoma Alismatis of 2.5～3.5 portions of Rhizoma Cyperis of Fructus Hordei Germinatus (parched)
0.5～1.5 part of 1.5～2.5 parts of Radix Bupleuri of 1.5～2.5 parts of Pericarpium Citri Reticulataes of Herba Leonuri
0.5～1.5 part of 1.5～2.5 parts of Rhizoma Chuanxiong of 1.5～2.5 parts of Fructus Aurantiis of Radix Rehmanniae Preparata
0.5～1.5 part of 0.5～1.5 part of Radix Angelicae Sinensis of 0.5～1.5 part of Flos Carthami of Radix Cyathulae.
The weight proportion of each crude drug of optimum formula of the present invention is:
1 part of 2 portions of Rhizoma Alismatis of 3 portions of Rhizoma Cyperis of Fructus Hordei Germinatus (parched)
1 part of 2 parts of Radix Bupleuri of 2 parts of Pericarpium Citri Reticulataes of Herba Leonuri
1 part of 2 parts of Rhizoma Chuanxiong of 2 parts of Fructus Aurantiis of Radix Rehmanniae Preparata
1 part of 1 part of Radix Angelicae Sinensis of 1 part of Flos Carthami of Radix Cyathulae.
Drug action mechanism among the present invention is as follows:
The Fructus Hordei Germinatus (parched) property of medicine is sweet, and is flat.Return spleen, stomach warp.Has promoting digestion and removing stagnation, the effect of galactopoiesis.Can treat food stagnation, abdominal distention is had loose bowels, nausea and vomiting, and inappetence, milk smoulders, distending pain of the breast etc.(the 1425th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Leonuri property of medicine suffering, hardship are slightly cold.Return liver, kidney, pericardium channel.Has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection etc.(the 2697th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
Rhizoma Cyperi property of medicine suffering, sweet, little hardship, flat.Return liver, tri-jiao channel.Has the resolving depression of regulating the flow of vital energy, regulating menstruation, antiabortive effect.Can treat distending pain over the hypochondrium, distending pain of the breast, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, frequent fetal movement etc.(the 2341st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Aurantii property of medicine hardship, acid are slightly cold.Return lung, spleen, stomach, large intestine channel.Has the chest stuffiness relieving of regulating the flow of vital energy, the effect of the stagnant removing food stagnancy of row.Can treat the septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen, heavy behind the dysentery, proctoptosis, uterine prolapse etc.(the 2227th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Flos Carthami property of medicine suffering, temperature.GUIXIN, Liver Channel.Has promoting blood circulation to restore menstrual flow, the effect of stasis-dispelling and pain-killing.Can treat the blood stasis amenorrhea, dysmenorrhea, postpartum stagnation stomachache, obstruction of qi in the chest and cardialgia ， mass in the abdomen knot is poly-, traumatic injury, arthralgia, apoplectic hemiplegia, macule etc.(the 2763rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Bupleuri nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Fructus Hordei Germinatus (parched), Rhizoma Cyperi and Radix Bupleuri; With Herba Leonuri, Flos Carthami, Radix Rehmanniae Preparata, Rhizoma Chuanxiong, Pericarpium Citri Reticulatae and Fructus Aurantii is ministerial drug; With Radix Cyathulae, Rhizoma Alismatis with when being classified as adjuvant.All medicines are harmonious, and are total to the tool liver-smoothing, qi-regulating, the effect of promoting blood flow to regulate menstruation.The treatment amenorrhea-galactorrhea syndrome has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment amenorrhea-galactorrhea syndrome of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat amenorrhea-galactorrhea syndrome, and the prevention of amenorrhea-galactorrhea syndrome is also had good effect, and the treatment amenorrhea-galactorrhea syndrome has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment amenorrhea-galactorrhea syndrome; Treatment amenorrhea-galactorrhea syndrome patient 24 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.12 examples of fully recovering account for 50%, and 8 examples that take a turn for the better account for 33.33%, and invalid 4 examples account for 16.67%, and total effective rate reaches 83.33%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction is pressed following weight weighting raw materials:
1 part of 2 portions of Rhizoma Alismatis of 3 portions of Rhizoma Cyperis of Fructus Hordei Germinatus (parched)
1 part of 2 parts of Radix Bupleuri of 2 parts of Pericarpium Citri Reticulataes of Herba Leonuri
1 part of 2 parts of Rhizoma Chuanxiong of 2 parts of Fructus Aurantiis of Radix Rehmanniae Preparata
1 part of 1 part of Radix Angelicae Sinensis of 1 part of Flos Carthami of Radix Cyathulae.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of treatment amenorrhea one galactorrhea syndrome that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.
Claims (3)
1. Chinese patent medicine for the treatment of amenorrhea-galactorrhea syndrome is characterized in that it is made by following raw materials by weight proportions:
0.1～2 part of 1.0～4 portions of Rhizoma Alismatis of 1.5～6 portions of Rhizoma Cyperis of Fructus Hordei Germinatus (parched)
0.1～2 part of 1.0～4 parts of Radix Bupleuri of 1.0～4 parts of Pericarpium Citri Reticulataes of Herba Leonuri
0.1～2 part of 1.0～4 parts of Rhizoma Chuanxiong of 1.0～4 parts of Fructus Aurantiis of Radix Rehmanniae Preparata
0.1～2 part of 0.1～2 part of Radix Angelicae Sinensis of 0.1～2 part of Flos Carthami of Radix Cyathulae.
2. a kind of Chinese patent medicine for the treatment of amenorrhea-galactorrhea syndrome according to claim 1, wherein the weight proportion of each crude drug is:
0.5～1.5 part of 1.5～2.5 portions of Rhizoma Alismatis of 2.5～3.5 portions of Rhizoma Cyperis of Fructus Hordei Germinatus (parched)
0.5～1.5 part of 1.5～2.5 parts of Radix Bupleuri of 1.5～2.5 parts of Pericarpium Citri Reticulataes of Herba Leonuri
0.5～1.5 part of 1.5～2.5 parts of Rhizoma Chuanxiong of 1.5～2.5 parts of Fructus Aurantiis of Radix Rehmanniae Preparata
0.5～1.5 part of 0.5～1.5 part of Radix Angelicae Sinensis of 0.5～1.5 part of Flos Carthami of Radix Cyathulae.
3. a kind of Chinese patent medicine for the treatment of amenorrhea-galactorrhea syndrome according to claim 1, wherein the weight proportion of each crude drug is:
1 part of 2 portions of Rhizoma Alismatis of 3 portions of Rhizoma Cyperis of Fructus Hordei Germinatus (parched)
1 part of 2 parts of Radix Bupleuri of 2 parts of Pericarpium Citri Reticulataes of Herba Leonuri
1 part of 2 parts of Rhizoma Chuanxiong of 2 parts of Fructus Aurantiis of Radix Rehmanniae Preparata
1 part of 1 part of Radix Angelicae Sinensis of 1 part of Flos Carthami of Radix Cyathulae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101209851A CN101112550A (en) | 2007-08-29 | 2007-08-29 | Chinese patent drug for treating amenorrhea-lactorrhea lactorrhea |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2007101209851A CN101112550A (en) | 2007-08-29 | 2007-08-29 | Chinese patent drug for treating amenorrhea-lactorrhea lactorrhea |
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| CN101112550A true CN101112550A (en) | 2008-01-30 |
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| CNA2007101209851A Pending CN101112550A (en) | 2007-08-29 | 2007-08-29 | Chinese patent drug for treating amenorrhea-lactorrhea lactorrhea |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102357170A (en) * | 2011-10-18 | 2012-02-22 | 文登市口腔医院 | Traditional Chinese medicine for treating qi stagnation and blood stasis type amenorrhea |
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2007
- 2007-08-29 CN CNA2007101209851A patent/CN101112550A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102357170A (en) * | 2011-10-18 | 2012-02-22 | 文登市口腔医院 | Traditional Chinese medicine for treating qi stagnation and blood stasis type amenorrhea |
| CN102357170B (en) * | 2011-10-18 | 2014-01-08 | 刘运波 | Traditional Chinese medicine for treating qi stagnation and blood stasis type amenorrhea |
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Open date: 20080130 |