CN109394979A - A kind of Tongning capsule and preparation method thereof for treating migraine - Google Patents
A kind of Tongning capsule and preparation method thereof for treating migraine Download PDFInfo
- Publication number
- CN109394979A CN109394979A CN201811540019.XA CN201811540019A CN109394979A CN 109394979 A CN109394979 A CN 109394979A CN 201811540019 A CN201811540019 A CN 201811540019A CN 109394979 A CN109394979 A CN 109394979A
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- parts
- scorpio
- uncaria
- tongning
- capsule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a kind of Tongning capsules and preparation method thereof for treating headache, by 50-150 parts of scorpio, 100-300 parts of uncaria, 50-150 parts of Rhizoma Chuanxiong, 30-120 parts of Rhizoma Gastrodiae, it is characterized in that: add decocting to take twice of extract uncaria, Rhizoma Chuanxiong, mild fire concentration, it is mixed with scorpio, Tall Gastrodis Tuber, 50 DEG C of low temperature dryings grind superfine end and cross 120 meshes, encapsulated, 0.3g/, radiosterilization.Chinese medicinal capsule is fabricated to by modern pharmaceutical method.The present invention has calming the liver to stop the wind, activating microcirculation and removing stasis medicinal, and the effect removed obstruction in channels to relieve pain can effectively treat migraine.
Description
Technical field
The present invention relates to a kind of Chinese patent drugs.
Background technique
Migraine is a kind of ictal and is often unilateral pulsatile headache.There is a large amount of patients shadow due to migraine in China
Ring work, studying and living.Drug therapy at present still based on simple anodyne, non-steroid anti-inflammatory drug and arcotic, this
Though class drug has certain curative effect, there is different degrees of damage to alimentary canal, cardiovascular system.Traditional Chinese medical science great master Zhu Liangchun professor
It took up a job as a doctor for more than 70 years, clinical experience abundant is had accumulated in terms for the treatment of migraine, " Tongning capsule " that early stage develops is (by complete
Scorpion, dried human placenta, hooked uncaria prescription composition), full side's tonifying Qi and blood, clearing phlegm for calming endogenous wind is removed obstruction in channels to relieve pain, and clinical application is significant in efficacy, it is rear because
Dried human placenta belongs to people tissue biological preparation, and the restricted medicinal material of country though being derived from the placenta of healthy puerpera, but still is inevitably deposited
In some pathogenic microorganisms for being not easy to detect, there is the risk for infecting unknown virus, weighed repeatedly and in line with treatment " taking human as
Originally criterion ", Zhu have found the Tongning capsule of completely new prescription with its small female Zhu Jian duckweed by many years Clinical Exploration, practice and research always
(by scorpio, uncaria, Rhizoma Chuanxiong, Rhizoma Gastrodiae) is not only significant in efficacy, but also safe without toxic side effect.Therefore, study it is such a " letter,
Just, honest and clean, test " Chinese patent drug, can bring glad tidings for many patients.
Summary of the invention
The purpose of the present invention is to provide a kind of Tongning capsules and its use for being formulated treatment migraine reasonable, significant in efficacy
On the way.
The technical solution of the invention is as follows:
A kind of Tongning capsule for treating migraine, it is characterized in that: being the Chinese patent drug made of the medicine material of following parts by weight:
50-150 parts of scorpio, 100-300 parts of uncaria, 50-150 parts of Rhizoma Chuanxiong, 30-120 parts of Rhizoma Gastrodiae, decocting is added to take uncaria, Rhizoma Chuanxiong
Twice of extract, mild fire concentration mixes, 50 DEG C of low temperature dryings with scorpio, Tall Gastrodis Tuber, grinds superfine end and crosses 120 meshes, encapsulated,
0.3g/, radiosterilization.
A kind of application of Tongning capsule in the drug of preparation treatment migraine.
The present invention have it is calming the liver to stop the wind, activating microcirculation and removing stasis medicinal is removed obstruction in channels to relieve pain, and the effect emptied is raised, and can effectively treat migraine.
Typical case:
One Guo patient of medical record so-and-so, female, 48 years old.Because " having a headache more than 20 year repeatedly " was in first visit on May 23 in 2015.Sore spot is not solid
It is fixed, to jump based on pain, very when with nausea and vomiting, readme head MR is shown no obvious abnormalities, and often breaking-out in nearly 1 year, which relies, takes morphine, is had
" hypoferric anemia " history, nearly half a year take complex prescription glue mucilage, difference of sleeping, Yi Xing, receive can, just adjust, pink tongue serves as a contrast that purple tongue fur is thin white, and arteries and veins is thin
It is soft.Dialectical: liver wind agitation empties dystrophy.Control preferably it is calming the liver to stop the wind, maintenance empties.Give Tongning capsule, one time 4, three times per day,
Half an hour warm water takes after meal.Headache attacks are primary during medication 20 days, continue one, delay after adding 1 Ibumetin Retavd
Solution, sometimes dizzy, sleep is temporarily without improvement, and continuous to give Tongning capsule and take, after even served March, monthly Headache attacks are primary substantially, but by
Decrescence light, the duration is obviously shortened, and dies in short-term sometimes, does not add anodyne again, occasionally there is dizziness, sleep improvement continues to take
With March, basic disappearance of having a headache, no dizziness, night, which sleeps, still pacifies, and is discontinued then.Follow-up is so far, even to have slight headache before menstruation, not shadow
Ring life.
Two patient Yang of medical record, female, 43 years old.On May 30th, 2017 is medical because of " migraine makees ten Yu " again.Have partially
Have a headache more than 20 years of history, based on left pillow, very when with nausea and vomiting, photophobia, hand shaking is repeatedly looked into the equal Non Apparent Abnormality of head CT, MR, is put down
When operating pressure it is big.Quarter examines: left pillow shouting pain is rubbed and is relaxed by feeling, consciously breaking-out is related with mood, fatigue, and timid cold, difference of sleeping is received with swollen
Can, it just adjusts, the dark violet tongue fur of pale tongue is thin white, the sublingual vessel stasis of blood, and arteries and veins is thin.Dialectical: liver wind agitation, obstruction of collaterals by blood stasis empty dystrophy.It controls and preferably puts down
Liver relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and disperse blood stasis and dredge collateral, maintenance empties.Give Tongning capsule, one time 4, three times per day, half an hour warm water takes after meal.It takes
After three weeks, headache stops, but uneasy sleeping at night, continuous to give Tongning capsule and take.Period takes an examination because reviewing, over fatigue, and headache has repeatedly,
The good time difference, continuously takes half a year when night sleeps, headache obviously have improvement, mood is also loosened earlier above, though excessively it is tired after have headache hair
Make, but can endure, and without discomforts such as nausea and vomiting, night, which sleeps, gradually pacifies, and in January, 2018 takes because of busy interruption so far, and headache is even
Make, can voluntarily alleviate in short-term, at present still in medication.
Below with reference to embodiment, the invention will be further described.
Specific embodiment
A kind of Tongning capsule is the medicine material following parts by weight by Chinese patent drug made of modern pharmaceutical method:
50-150 parts of scorpio (50 parts, 100 parts, 150 parts of example), 100-300 parts of uncaria (100 parts, 200 parts, 300 parts of example), Rhizoma Chuanxiong
50-150 parts (50 parts, 100 parts, 150 parts of example), 30-120 parts of Rhizoma Gastrodiae (30 parts, 70 parts, 120 parts of example);Preparation method: by uncaria,
Rhizoma Chuanxiong adds decocting to take twice of extract, and mild fire concentration mixes, 50 DEG C of low temperature dryings with scorpio, Tall Gastrodis Tuber, grinds superfine end and crosses 120
Mesh, it is encapsulated, 0.3g/, radiosterilization.
A kind of application of Tongning capsule in the drug of preparation treatment migraine.
Usage: Chinese medicinal capsule is made by modern pharmaceutical method in top, and every 0.3g, 4 tablets each time, 3 times a day, half is small after meal
Shi Wenshui takes.
Claims (2)
1. a kind of Tongning capsule for treating migraine, it is characterized in that: the Chinese medicinal capsule made by the medicine material of following parts by weight:
50-150 parts of scorpio, 100-300 parts of uncaria, 50-150 parts of Rhizoma Chuanxiong, 30-120 parts of Rhizoma Gastrodiae;Preparation method: by uncaria, Rhizoma Chuanxiong
Decocting is added to take twice of extract, mild fire concentration mixes, 50 DEG C of low temperature dryings with scorpio, Tall Gastrodis Tuber, and it grinds superfine end and crosses 120 meshes,
It is encapsulated.
2. a kind of preparation method for the Tongning capsule for treating migraine, it is characterized in that: adding decocting to take extract two uncaria, Rhizoma Chuanxiong
Time, mild fire concentration mixes, 50 DEG C of low temperature dryings with scorpio, Tall Gastrodis Tuber, grinds superfine end and crosses 120 meshes, encapsulated;Each component
Parts by weight: 50-150 parts of scorpio, 100-300 parts of uncaria, 50-150 parts of Rhizoma Chuanxiong, 30-120 parts of Rhizoma Gastrodiae.
Priority Applications (1)
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CN201811540019.XA CN109394979B (en) | 2018-12-17 | 2018-12-17 | Tongning capsule for treating migraine and preparation method thereof |
Applications Claiming Priority (1)
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CN201811540019.XA CN109394979B (en) | 2018-12-17 | 2018-12-17 | Tongning capsule for treating migraine and preparation method thereof |
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CN109394979A true CN109394979A (en) | 2019-03-01 |
CN109394979B CN109394979B (en) | 2021-04-06 |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1596934A (en) * | 2004-07-30 | 2005-03-23 | 吉林敖东洮南药业股份有限公司 | Head ache capsule preparation |
CN101032604A (en) * | 2007-04-16 | 2007-09-12 | 北京艺信堂医药研究所 | Chinese medicine preparation for curing vascular type headache |
CN101708315A (en) * | 2009-12-04 | 2010-05-19 | 卢速江 | Chinese medicinal preparation for treating headache and preparation method thereof |
CN102028783A (en) * | 2011-01-05 | 2011-04-27 | 朱良春 | Pain-relieving capsules, production method thereof and application thereof |
CN103495114A (en) * | 2013-09-24 | 2014-01-08 | 巫军 | Traditional Chinese medicine composition for treating migraine |
CN108310232A (en) * | 2017-01-17 | 2018-07-24 | 淄博夸克医药技术有限公司 | A kind of Chinese medicine for treating migraine |
-
2018
- 2018-12-17 CN CN201811540019.XA patent/CN109394979B/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1596934A (en) * | 2004-07-30 | 2005-03-23 | 吉林敖东洮南药业股份有限公司 | Head ache capsule preparation |
CN101032604A (en) * | 2007-04-16 | 2007-09-12 | 北京艺信堂医药研究所 | Chinese medicine preparation for curing vascular type headache |
CN101708315A (en) * | 2009-12-04 | 2010-05-19 | 卢速江 | Chinese medicinal preparation for treating headache and preparation method thereof |
CN102028783A (en) * | 2011-01-05 | 2011-04-27 | 朱良春 | Pain-relieving capsules, production method thereof and application thereof |
CN103495114A (en) * | 2013-09-24 | 2014-01-08 | 巫军 | Traditional Chinese medicine composition for treating migraine |
CN108310232A (en) * | 2017-01-17 | 2018-07-24 | 淄博夸克医药技术有限公司 | A kind of Chinese medicine for treating migraine |
Non-Patent Citations (2)
Title |
---|
车光锡等: "天麻钩藤饮加减治疗偏头痛对照观察", 《实用中医内科杂志》 * |
高颖等: "《中医临床诊疗指南释义 脑病分册》", 30 September 2015, 中国中医药出版社 * |
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