CN1164407A - New medicine for curing burn, traumatism and preparation method thereof - Google Patents

New medicine for curing burn, traumatism and preparation method thereof Download PDF

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Publication number
CN1164407A
CN1164407A CN 96118155 CN96118155A CN1164407A CN 1164407 A CN1164407 A CN 1164407A CN 96118155 CN96118155 CN 96118155 CN 96118155 A CN96118155 A CN 96118155A CN 1164407 A CN1164407 A CN 1164407A
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radix
medicine
parts
burn
radix angelicae
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CN 96118155
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CN1060365C (en
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宋伟国
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HUNAN SHAOYANG HUARENTANG PHARMACEUTICAL DEVELOPMENT Co Ltd
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Abstract

The present invention discloses a new medicine for curing burn and traumatism and its preparation method. It is a liquid medicine made up by using the Chinese medicinal materials of dahurian angelica root, puccoon, licorice, Chinese angelica root, white wax, dragon's blood, borneol and sesame oil as raw materials through a certain preparation process. Said invented medicine possesses strong antiseptic function, can quickly stop pain and uses exposure therapy, so that it is convenient for use, and possesses obvious therapeutic effect for treating various burns, traumata, wound infection, innominate inflammatory swelling and bed sore, etc..

Description

A kind of new drug and preparation method for the treatment of burn, wound infections
The present invention relates to a kind of new drug for the treatment of burn, wound infections, specifically compound Chinese medicinal preparation.The invention still further relates to the manufacture method of this medicine.
Burn, scald, chemical burn, wound, be a kind of common, come accidental wound suddenly, the patient suffering, heavy then threat to life brings serious economic problems and social problem to family social.In existing many burn medicines,, also has unsatisfactory part owing to many reasons such as prescription and making.Some analgesic effect is poor, and a little less than some antibacterial action, some skin moistening skin-protecting function is poor, some blood activating and promoting tissue regeneration function is poor, some patient misery of changing dressings, and doctor's labor intensity is big, some therapeutic domain is little, and overemphasized gnotobasis is not suitable for vast rural area and different medical unit and uses.War or earthquake particularly taking place, large quantities of wounded occur, then feels simply helpless especially.The Chinese patent communique discloses some burn medicines, as publication number CN1065014, CN1068495, CN107538, CN1079163 etc.Treatment at present burns preferably that medicine is the moist expose burn ointment of Beijing bright Academy of Traditional Chinese Medicine development, and this medicine is found a good sale in more than 20 countries and regions in the world, is national major scientific and technological achievement and national new drug.This medicine reaches not infective wound surface to 1 degree, 2 degree burn patients, and curative effect is fine.But to the infection suppurates wound surface, antibacterial and anti-inflammation functions is undesirable.Because three big difficulties of treatment burn, the one, pain, the 2nd, dehydration, the 3rd, infect.And infect is modal difficulty, can't resolve if infect to close, and that this medicine is just not very desirable.
The object of the present invention is to provide a kind of pain relieving fast, antibacterial action is strong, eutherapeutic burn and wound healing agent.Another object of the present invention provides the preparation method of this burn, wound healing agent.
The objective of the invention is to realize that by following technical proposals a kind of medicine for the treatment of burn, wound is the medicament of being made by the following weight proportion raw material:
Oleum Sesami 600--1000 part Radix Angelicae Sinensis 25--50 part Radix Angelicae Dahuricae 25--51 part
Radix Arnebiae (Radix Lithospermi) 25--55 part Radix Glycyrrhizae 25--60 part white beeswax 1--5 part
Sanguis Draxonis 1--20 part Borneolum Syntheticum 20--40 part
Medicine preferred weight proportioning of the present invention is:
25 parts of 25 parts of Radixs Angelicae Dahuricae of 600 parts of Radix Angelicae Sinensis of Oleum Sesami
2 parts of 25 parts of white beeswax of 24 portions of Radix Glycyrrhizaes of Radix Arnebiae (Radix Lithospermi)
20 parts of 10 parts of Borneolum Syntheticums of Sanguis Draxonis
The preparation method of medicine of the present invention is:
A, take by weighing each raw material by formula proportion;
B, Radix Angelicae Sinensis, the Radix Angelicae Dahuricae, Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae are put into Oleum Sesami soaked 1-3 days;
C, will soak medicine heating one hour, treat that temperature stops heating when reaching 200 ℃;
D, elimination medicinal residues add Sanguis Draxonis, white beeswax, Borneolum Syntheticum again, medicament.
This medicine is a red liquid, thickness slightly, and the tool aromatic odor, nontoxic, nonirritant is pure Chinese medicine compound liquid preparation, temporarily called after " wound oil is scalded in China ".
Medicine of the present invention is through animal experiment and clinical trial, and the result shows: this medical instrument has anti-inflammation, detumescence, pain relieving, invigorates blood circulation, the function of granulation promoting.Evident in efficacy to treatment water, burning hot wound, chemical burn, electric burn, dark 2 degree and 3 degree wound surface.Be characterized in that 1. pain relieving is fast, but pain relieving in 1-3 minute; 2. antibacterial action is strong, the infective wound surface coating once, can form a scab next day, generally do not need injection of antibiotics; 3. adopt exposure method, easy to use, need not wrap up; 4. medical expense is low, but than conventional therapy cost saving 50-90%; 5. cure soon, alleviate patient's misery; 6. generally do not require under the gnotobasis and operate.
Nineteen ninety-five, the inventor is scalded wound oil with China and is carried out every contrast test with Pekinese's moist expose burn ointment, successively does local toxicity test, skin irritation test, scalds contrast test, invigorates blood circulation and antibacterial tests with 60 Kunming kind white mice and 4 TWOs.Result of the test: preceding 2 tests, two kinds of equal avirulences of medicament, non-stimulated, zero difference.Scald contrast test, every group with 10 of white mice, all cuts off left side buttocks hair, causes 2 * 1cm to scald face with 90 ℃ boiled water, and coating respectively all heals with wound surface in 8 days of medicine of the present invention, with 10 days of moist expose burn ointment healing substantially.Invigorate blood circulation and antibacterial tests, the white mice tail is cut off 1/2 or 1/3, the first group is coated with medicine of the present invention, and the second group is coated with moist expose burn ointment, obvious difference after 3 days, and the dry incrustation of the wound surface of first group, the white mice activity is freely.The really stagnant state of the appearance of second group, the wound has secretions to overflow.After 8 days, the white mice tail of first group survives, and the white mice tail of second group is withered to diminish.In addition, artificially antibacterial is put into the white mouse wound face, causes infection, the antibacterial and anti-inflammation functions of medicine of the present invention obviously is better than moist expose burn ointment as a result.Henceforth, do contrast test with the burn cream of Hong Kong, the U.S. again, the analgesic antiphlogistic effect of medicine of the present invention is all excellent as a result.
Example surplus clinical drug of the present invention uses 600, effective percentage 100%, and obviously be better than various burn medicines.Now enumerating several cases is described below:
1, Li Tingting, woman, 3 years old, the woman of the Shaoyang City suburb Li Le of public security bureau honor, boiled water is scalded two lower limb, is diagnosed as shallow 2 degree and scalds area 20%, once be in hospital 27 days in Shaoyang City hospital, wound surface is coated with moist expose burn ointment, and cooperates supporting treatments such as antibiotic therapy and blood transfusion, shared go surplus the medical fee 5000 yuan, traumatic infection becomes 3 degree by shallow 2 degree, and body temperature continues at 39 ℃.After the inventor uses medicine of the present invention instead, i.e. incrustation after 24 hours, all antibiotic of stopping using after coating 2 times, body temperature is reduced to 37 ℃ two days later, the band medicine goes home to treat after three days, once a day, and wound surface recovery from illness in 15 days, do not make skin graft, do not influence function yet, only spend surplus the medical fee 100 yuan.
2, Zhou Lanying, the woman, 32 years old, Shaoyang City Shuan Po mountain range four company's families of workers and staff were scalded face because of pressure cooker cooks congee, and treat 4 days with moist expose burn ointment in city's fire-fighting detachment earlier, spend more than 600 yuan of medical fee, and facial swelling is more very.After being coated with China, the inventor scalds wound oil once, whole detumescences of a face in evening and incrustation, and form a scab was coated with once in back two days, recovery from illness after 3 days, preventing from scar, even also show young, beautiful before the ratio scald.
3, Yang Lan, woman, 20 years old, three workers of place of Hu'nan Prov. No.4 Engineering Co., because of traumatic injury causes the paraplegia long-term bed, cause the large stretch of skin ischemic necrosis in buttocks back to suppurate, produce Ceftriaxone treatment with the U.S. every day, medical fee was more than 400 yuan in one day, and traumatic infection suppurates, and all there is one foul smell in whole corridor.Wound oil is scalded with China in the back, is coated with every day once, and just control traumatic infection in 3 days, and fresh granulation tissue occurs, and inactive antibiotics.Wound healing after March.For company saves nearly 100,000 yuan of medical fee.
In August nineteen ninety-five, this medicine is openly on probation in worker's hospital of Hu'nan Prov. No.4 Engineering Co., because of evident in efficacy, has been subjected to medical circle and patient's popular welcome and praise.How tame news units such as " Shaoyang daily paper ", Shaoyang television station, " Shenzhen Special Zone Daily " have given report.Former leader Mr. Pan Junqi of the United Front Work Department of the Central Committee very appreciated after using this medicine, and inventor and this medicine was introduced to Hunan Province vice-governor Wang Keying.On March 22nd, 1996, professor expert that Hunan Province Department of Public Health convenes units such as Hunan College of Traditional Chinese Medicine, Research Inst. of Traditional Chinese Medicine, Hunan Medical University adopts unanimously the review of setting up the project of this medicine.This medicine has now caused the concern and the attention of international medical community.
Embodiment: select for use quality to meet the raw material of Chinese medicine of Chinese Pharmacopoeia regulation, take by weighing Oleum Sesami 600Kg by prescription, Radix Angelicae Sinensis 25kg, Radix Angelicae Dahuricae 25kg, Radix Arnebiae (Radix Lithospermi) 24kg, Radix Glycyrrhizae 25kg, white beeswax 22kg, Sanguis Draxonis 10kg, Borneolum Syntheticum 20kg.Earlier Radix Angelicae Sinensis, the Radix Angelicae Dahuricae, Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae being put into Oleum Sesami soaked 3 days; To soak medicine heating 1 hour then, and continue to heat up and treat that temperature stops heating when reaching 200 ℃; The elimination medicinal residues add Sanguis Draxonis, white beeswax, Borneolum Syntheticum again, medicament.Pack with bottle, mark medicine name, function cure mainly, usage gets final product with heavily waiting.

Claims (4)

1, a kind of medicine for the treatment of burn, wound infections is characterized in that it is the medicament of being made by the following weight proportion raw material:
Oleum Sesami 600--1000 part Radix Angelicae Sinensis 25--50 part Radix Angelicae Dahuricae 25--51 part
Radix Arnebiae (Radix Lithospermi) 25--55 part Radix Glycyrrhizae 25--60 part white beeswax 1--5 part
Sanguis Draxonis 1--20 part Borneolum Syntheticum 20--40 part
2, the medicine of treatment burn according to claim 1, wound infections, wherein the weight proportion of each raw material is:
25 parts of 25 parts of Radixs Angelicae Dahuricae of 600 parts of Radix Angelicae Sinensis of Oleum Sesami
2 parts of 25 parts of white beeswax of 24 portions of Radix Glycyrrhizaes of Radix Arnebiae (Radix Lithospermi)
20 parts of 10 parts of Borneolum Syntheticums of Sanguis Draxonis
3, the medicine of treatment burn according to claim 1 and 2, wound infections is characterized in that said medicament is a liquid, and medicinal liquid is red, and thickness has aromatic odor slightly.
4, the preparation method of the described medicine of claim 1 is characterized in that:
A, take by weighing each raw material by formula proportion;
B, Radix Angelicae Sinensis, the Radix Angelicae Dahuricae, Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae are put into Oleum Sesami soaked 1-3 days;
C, will soak medicine heating one hour, treat that temperature stops heating when reaching 200 ℃;
D, elimination medicinal residues add Sanguis Draxonis, white beeswax, Borneolum Syntheticum again, medicament.
CN96118155A 1996-05-08 1996-05-08 New medicine for curing burn, traumatism and preparation method thereof Expired - Fee Related CN1060365C (en)

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Application Number Priority Date Filing Date Title
CN96118155A CN1060365C (en) 1996-05-08 1996-05-08 New medicine for curing burn, traumatism and preparation method thereof

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CN1060365C CN1060365C (en) 2001-01-10

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1053836C (en) * 1997-09-03 2000-06-28 田明行 Ointment for wounds and sores and preparation thereof
CN100372562C (en) * 2003-05-19 2008-03-05 魏茂武 Bedsore ointment and its prepn process
CN101406583B (en) * 2008-11-28 2011-05-25 邹连琦 Externally applied Chinese medicine ointment for treating pyogenic skin infection caused by skin traumatism
CN102512573A (en) * 2012-01-14 2012-06-27 许从玉 Nursing liquid for promoting wound healing
CN103007000A (en) * 2013-01-11 2013-04-03 湖南邵阳华仁堂药业发展有限公司 New medicine for treating burns and wounds and preparation method thereof
CN104474187A (en) * 2014-11-18 2015-04-01 张大群 Traditional Chinese medicine plaster for treating scald and abscess
CN108186729A (en) * 2018-03-08 2018-06-22 上海市第七人民医院 A kind of Chinese medicine composition and its application
CN108310160A (en) * 2018-04-27 2018-07-24 李永建 A kind of Chinese medicine composition for treating bedsore
CN109758530A (en) * 2019-01-31 2019-05-17 凤庆县中医医院 A kind of External used shengji paste
CN110279785A (en) * 2019-07-08 2019-09-27 亳州职业技术学院 A kind of skin repairing dahurian angelica pain-relieving powder and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1052789A (en) * 1989-07-31 1991-07-10 周学林 A kind of preparation method of ointment for treating burn

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1053836C (en) * 1997-09-03 2000-06-28 田明行 Ointment for wounds and sores and preparation thereof
CN100372562C (en) * 2003-05-19 2008-03-05 魏茂武 Bedsore ointment and its prepn process
CN101406583B (en) * 2008-11-28 2011-05-25 邹连琦 Externally applied Chinese medicine ointment for treating pyogenic skin infection caused by skin traumatism
CN102512573A (en) * 2012-01-14 2012-06-27 许从玉 Nursing liquid for promoting wound healing
CN102512573B (en) * 2012-01-14 2013-05-08 崔合芳 Nursing liquid for promoting wound healing
CN103007000A (en) * 2013-01-11 2013-04-03 湖南邵阳华仁堂药业发展有限公司 New medicine for treating burns and wounds and preparation method thereof
CN104474187A (en) * 2014-11-18 2015-04-01 张大群 Traditional Chinese medicine plaster for treating scald and abscess
CN108186729A (en) * 2018-03-08 2018-06-22 上海市第七人民医院 A kind of Chinese medicine composition and its application
CN108310160A (en) * 2018-04-27 2018-07-24 李永建 A kind of Chinese medicine composition for treating bedsore
CN109758530A (en) * 2019-01-31 2019-05-17 凤庆县中医医院 A kind of External used shengji paste
CN110279785A (en) * 2019-07-08 2019-09-27 亳州职业技术学院 A kind of skin repairing dahurian angelica pain-relieving powder and preparation method thereof

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Applicant after: Shaoyang Hunan Shan Xiu Pharmaceutical Chemical Co., Ltd.

Applicant before: Song Weiguo

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Owner name: HUNAN SHAOYANG HUARENTANG PHARMACEUTICAL DEVELOPME

Free format text: FORMER NAME: HUNAN SHAOYANG SHANXIU MEDICINE CHEMICAL INDUSTRY CO., LTD.

CP03 Change of name, title or address

Address after: Hunan nine Shaoyang County Public Bridge Industrial Development Zone

Patentee after: Hunan Shaoyang Huarentang Pharmaceutical Development Co., Ltd.

Address before: Hunan nine Shaoyang County Public Bridge Industrial Development Zone

Patentee before: Shaoyang Hunan Shan Xiu Pharmaceutical Chemical Co., Ltd.

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Granted publication date: 20010110

Termination date: 20110508