CN113368202A

CN113368202A - Externally-applied soaking cold compress liquid for burns and scalds and preparation method thereof

Info

Publication number: CN113368202A
Application number: CN202110713103.2A
Authority: CN
Inventors: 周莲鹏
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-06-25
Filing date: 2021-06-25
Publication date: 2021-09-10

Abstract

The invention relates to the technical field of burn and scald treatment medicines, and discloses an external soaking cold compress liquid for burns and scalds and a preparation method thereof, wherein the external soaking cold compress liquid is prepared from the following raw materials in parts by weight: 0.5 part of rock candy, 5-10 parts of mint, 5-10 parts of yellow chrysanthemum, 5-10 parts of rose, 5-10 parts of dandelion, 15-20 parts of radix sophorae flavescentis, 5-10 parts of phellodendron, 10-15 parts of groundsel, 5-10 parts of clove, 5-8 parts of borneol, 5-10 parts of fructus cnidii, 5-10 parts of radix stemonae and 0.03-0.05 part of chlorhexidine acetate solution, and ganoderma lucidum water and spring water which are used as bases of cold compress liquid. The preparation method comprises the steps of adding crystal sugar, mint, yellow chrysanthemum, rose, dandelion, sophora flavescens, phellodendron, climbing groundsel herb, clove, borneol, fructus cnidii and radix stemonae into spring water, mixing, soaking, mixing with ganoderma lucidum water according to the mass ratio of 1:1, standing for 120 days, and adding chlorhexidine acetate solution to obtain a finished product. The cold compress liquid provided by the invention has the good effects of clearing heat and cooling blood, resisting bacteria and diminishing inflammation, relieving pain and pain, removing the necrotic tissue and promoting granulation, promoting the rapid healing of wound surfaces and causing no scars after healing.

Description

Externally-applied soaking cold compress liquid for burns and scalds and preparation method thereof

Technical Field

The invention relates to the technical field of burn and scald treatment, in particular to an external soaking cold compress liquid for burn and scald and a preparation method thereof.

Background

The scald is the damage to skin and mechanism caused by high temperature, strong light, heat radiation and the like caused by external factors, and the causes of the scald comprise flame, hot iron, boiling oil, boiled water, soup, electric arc, chemical substances and the like. The clinical manifestations vary according to the degree of injury and the size of the area, and mild patients have red, swollen, hot, painful or blistering skin as the main symptoms; the severe cases can go deep into the muscles and bones and cause general changes such as shock and infection. The treatment and nursing after the scald are particularly critical, and the main principle is to repair the autologous skin as much as possible, reduce infection, accelerate the healing speed and reduce the generation of skin necrosis. If the treatment is not carried out in time, the malignant phenomena of skin rot and suppuration and the like can be caused, and even sequela such as scars and the like can appear in the later period.

At present, the treatment medicines and the treatment methods mainly adopt western medicine as main treatment medicines and treatment measures. Western medicine advocates the treatment of wound inflammation diminishing, antibiosis and pain relieving, then cleans necrotic cells, then binds up, advocates the treatment of wound without advocating the application of medicine to the wound, and mainly uses internal medicine, so the method cannot actually achieve good treatment effect, and the treatment cost is extremely high, and in addition, western medicine may contain hormone and is often accompanied with side effects. Some traditional Chinese medicine scald ointment has good effect, but in the using process, secretion of a wound surface needs to be scraped for many times, so that a patient is painful, and the infection chance is increased. Moreover, the medicines for treating burns and scalds sold on the market can not effectively relieve pain and pain for both mild burns and scalds and severe burns and scalds, can not effectively diminish inflammation and sterilize, can easily cause repeated bubbles at the burned and scalded parts, and have slow recovery time and painful recovery process. The ideal scald medicine needs to have good broad-spectrum antibacterial effect, is not easy to generate drug resistance, has the effects of promoting epithelial cell growth, keeping moist microenvironment of a wound surface and the like, and also has the characteristics of analgesia, pain relief, rapid tissue regeneration, convenience in use and the like.

In conclusion, the problem to be solved by the technical personnel in the field is how to provide a medicament for treating scald, which has good curative effect, convenient use and good experience of patients.

Disclosure of Invention

Technical problem to be solved

The embodiment of the invention provides an external soaking cold compress liquid for burns and scalds and a preparation method thereof, which are used for providing an external soaking liquid or cold compress liquid with better curative effect on burns and scalds.

Disclosure of the invention

The embodiment of the invention provides an external soaking cold compress liquid for burns and scalds, which is prepared from the following raw materials in parts by weight: 0.5 part of rock candy, 5-10 parts of mint, 5-10 parts of yellow chrysanthemum, 5-10 parts of rose, 5-10 parts of dandelion, 15-20 parts of radix sophorae flavescentis, 5-10 parts of phellodendron, 10-15 parts of groundsel, 5-10 parts of clove, 5-8 parts of borneol, 5-10 parts of fructus cnidii, 5-10 parts of radix stemonae, 0.03-0.05 part of chlorhexidine acetate solution, and 5-15 parts of ganoderma lucidum water and 10-15 parts of spring water which are used as bases of cold compress liquid.

Preferably, the external soaking cold compress liquid for burns and scalds comprises the following raw materials in parts by weight: 0.5 part of rock candy, 5 parts of mint, 5 parts of yellow chrysanthemum, 5 parts of rose, 5 parts of dandelion, 15 parts of sophora flavescens, 5 parts of golden cypress, 10 parts of groundsel, 5 parts of clove, 5 parts of borneol, 5 parts of fructus cnidii, 5 parts of radix stemonae, 0.03 part of chlorhexidine acetate solution, and 10 parts of ganoderma lucidum water and spring water which are used as bases of cold compress liquid.

Preferably, the external soaking cold compress liquid for burns and scalds comprises the following raw materials in parts by weight: 0.5 part of rock candy, 10 parts of mint, 10 parts of yellow chrysanthemum, 10 parts of rose, 10 parts of dandelion, 20 parts of radix sophorae flavescentis, 10 parts of golden cypress, 15 parts of groundsel, 10 parts of clove, 8 parts of borneol, 10 parts of fructus cnidii, 10 parts of radix stemonae, 0.05 part of chlorhexidine acetate solution, and 15 parts of ganoderma lucidum water and 15 parts of spring water which are used as bases of cold compress liquid.

Preferably, the external soaking cold compress liquid for burns and scalds comprises the following raw materials in parts by weight: 0.5 part of rock candy, 8 parts of mint, 8 parts of yellow chrysanthemum, 8 parts of rose, 8 parts of dandelion, 17 parts of sophora flavescens, 8 parts of golden cypress, 12 parts of groundsel, 7 parts of clove, 6 parts of borneol, 8 parts of fructus cnidii, 8 parts of radix stemonae, 0.04 part of chlorhexidine acetate solution, and 12 parts of ganoderma lucidum water and spring water which are used as bases of cold compress liquid.

Simultaneously, the preparation method of the external soaking cold compress liquid for burns and scalds is also provided, and comprises the following steps:

the method comprises the following steps: taking 0.5 part of rock candy, 5-10 parts of mint, 5-10 parts of yellow chrysanthemum, 5-10 parts of rose, 5-10 parts of dandelion, 15-20 parts of radix sophorae flavescentis, 5-10 parts of phellodendron, 10-15 parts of groundsel, 5-10 parts of clove, 5-8 parts of borneol, 5-10 parts of fructus cnidii and 5-10 parts of radix stemonae, adding 10-15 parts of spring water, mixing and soaking;

step two: preparing the ganoderma lucidum water: placing 0.2-0.4 part of ganoderma lucidum into a glass bottle, adding 10 parts of purified water and 0.5 part of rock candy, placing the glass bottle in a shade place without sunlight irradiation, and soaking for one year;

step three: mixing the mixed solution obtained in the step one with the ganoderma lucidum water in the step two according to the mass ratio of 1:1, and standing for 120 d;

step four: and (3) taking out the liquid medicine obtained in the third step, and adding a chlorhexidine acetate solution to obtain the external soaking cold compress liquid for burns and scalds.

The medicinal mechanism of the invention is as follows: the externally applied soaking cold compress liquid for burns and scalds combines Chinese and Western medicines, adopts a method for treating both symptoms and root causes, selects Chinese herbal medicine raw materials of disinfection and hemostasis, inflammation diminishing and swelling diminishing, wind and heat dispelling, hot and hot pressure fire and gas releasing, blood circulation promoting and blood stasis removing, sterilization and heat clearing and the like, and is mixed with self-made ganoderma lucidum water and western medicine chlorhexidine acetate (the western medicine chlorhexidine acetate mainly has the effects of sterilization and virus elimination) according to a certain amount to prepare liquid medicine. Wherein, the medicinal mechanism of the ganoderma lucidum water is as follows: (1) the immunity is enhanced because the invasion of virus and bacteria must be strictly prevented in the process of wound healing, otherwise, the wound is inflamed and is difficult to heal. The ganoderma lucidum water can fast phagocytize virus and bacteria, inhibit the growth of the bacteria and help wounds to diminish inflammation and relieve pain, namely the effect of diminishing inflammation and relieving pain is achieved. (2) The ganoderma lucidum water is rich in various nutrients and can help wound healing. The cultured ganoderma lucidum water is scientifically tested, is rich in more than 40 nutrient substances such as amino acid, protein and the like, and can increase the cell activity, enable a human body to generate anti-infection capacity, improve the cell metabolism function and accelerate the wound healing. Moreover, the nutrient substances in the ganoderma lucidum water can further improve the immunity and the resistance of the human body, and after the body is strong, the blood platelets in the blood can be increased, thereby helping the wound healing. The raw materials are mixed together to achieve the best treatment effect, and can play an auxiliary role.

(III) advantageous effects

The external soak solution or cold compress solution for burns and scalds provided by the invention has the advantages that the selected raw material medicines are appropriate in compatibility, the compatibility of the raw material medicines accords with the theories of traditional Chinese medicine and modern medicine, the external soak solution or cold compress solution has the effects of clearing heat, expelling toxin, relieving pain, diminishing inflammation and resisting bacteria, the wound surface is promoted to heal quickly, the treatment recovery time is short, no scar is left after healing, and the treatment effect is obvious. The invention can achieve the best treatment effect of each raw material medicine in the invention by optimally distributing and proportioning the raw material medicines and simultaneously can play an auxiliary role. The formula is an external application formula, is safe, does not have side effects, has obvious effects, is convenient to use when the prepared external liquid is used for soaking or cold compressing affected parts, adopts common medicines as raw materials, has wide raw materials, is simple to process and manufacture, has low cost, is suitable for batch production, can be applied externally and soaked in two application methods, and is suitable for various burns and scalds.

Meanwhile, all the existing burn and scald medicines can not effectively relieve pain and alleviate pain, can not effectively diminish inflammation and sterilize, can not bubble repeatedly, and have long recovery time, and the recovery process is painful. The soaking cold compress liquid is used according to the using method of the invention, so that the effects of stopping pain and easing pain can be rapidly achieved, the pain feeling caused by burn and scald can be relieved for patients, the necrosis and the granulation can be removed, the injection and the skin grafting are avoided, the treatment and recovery time is short, the healing is free from scars, the side effects and the sequelae, the soaking cold compress liquid is suitable for various crowds, and the major defect of all existing burn and scald medicines is effectively overcome.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are a part of the embodiments of the present invention, but not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1:

an external soaking cold compress liquid for burns and scalds comprises the following raw materials in parts by weight: 0.5 part of rock candy, 5 parts of mint, 5 parts of yellow chrysanthemum, 5 parts of rose, 5 parts of dandelion, 15 parts of sophora flavescens, 5 parts of golden cypress, 10 parts of groundsel, 5 parts of clove, 5 parts of borneol, 5 parts of fructus cnidii, 5 parts of radix stemonae, 0.03 part of chlorhexidine acetate solution, and 10 parts of ganoderma lucidum water and spring water which are used as bases of cold compress liquid.

The preparation method comprises the following steps: adding spring water into the rock candy, mint, yellow chrysanthemum, rose, dandelion, sophora flavescens, phellodendron, groundsel, clove, borneol, fructus cnidii and radix stemonae, mixing and soaking, mixing with ganoderma lucidum water according to the mass ratio of 1:1, standing for 120d, taking out the mixed liquid medicine, and adding chlorhexidine acetate solution to obtain a finished product.

Example 2:

an external soaking cold compress liquid for burns and scalds comprises the following raw materials in parts by weight: 0.5 part of rock candy, 10 parts of mint, 10 parts of yellow chrysanthemum, 10 parts of rose, 10 parts of dandelion, 20 parts of radix sophorae flavescentis, 10 parts of golden cypress, 15 parts of groundsel, 10 parts of clove, 8 parts of borneol, 10 parts of fructus cnidii, 10 parts of radix stemonae, 0.05 part of chlorhexidine acetate solution, and 15 parts of ganoderma lucidum water and 15 parts of spring water which are used as bases of cold compress liquid.

Example 3:

an external soaking cold compress liquid for burns and scalds comprises the following raw materials in parts by weight: 0.5 part of rock candy, 8 parts of mint, 8 parts of yellow chrysanthemum, 8 parts of rose, 8 parts of dandelion, 17 parts of sophora flavescens, 8 parts of golden cypress, 12 parts of groundsel, 7 parts of clove, 6 parts of borneol, 8 parts of fructus cnidii, 8 parts of radix stemonae, 0.04 part of chlorhexidine acetate solution, and 12 parts of ganoderma lucidum water and spring water which are used as bases of cold compress liquid.

The application method of the externally used soaking cold compress liquid for burns and scalds is divided into two methods, namely cold compress and soaking:

1. cold compress: for the injured part which is inconvenient to soak, the medical gauze can be used for soaking the liquid medicine for cold compress of the injured part, the liquid medicine is changed back and forth and then applied to the injured part, and the injured part is slowly changed from red to white without any pain. The time for applying the liquid medicine is determined according to the degree of injury. Generally, mild burns and scalds are about 2 hours, severe burns and scalds are 6 to 7 hours, and the red and swollen bubbles of the parts which are already red and swollen and foamed can disappear after the cold compress time reaches 3 hours.

2. Soaking: for the injured part which is convenient to soak, the soaking treatment can be selected, and the soaking effect is better than the cold compress effect. When the liquid medicine is used, part of the liquid medicine is taken out, the injured part of the liquid medicine is completely soaked in the liquid medicine, and the liquid medicine is changed every half an hour until the injured part is slowly changed from red to white without any pain feeling. The soaking time can be determined according to the injury degree, and generally, the soaking time for mild scald is about 2 hours, and the soaking time for severe scald is about 5 hours.

Clinical experiments are as follows:

(1) the cases are as follows: the number of patients with scald is 100. Among them, 60 cases of first degree scald, 20 cases of superficial second degree scald and 20 cases of deep second degree scald.

(2) Grouping: the above cases were divided into two groups (test group and control group), with no significant difference in age, sex, degree of scald between the two groups, and each group was equally divided into three groups according to the degree of scald (see table 1 below).

Test groups, the burn and scald liquids of the examples 1 to 3 are respectively used for direct cold compress or soaking the wound; the control group was applied with a commercially available ointment for scald, and used according to the instructions.

(3) Evaluation criteria: according to the scald curative effect standard of the Chinese medical society:

and (3) curing: the wound pain disappears after the treatment, the exudation is obviously reduced, the first degree scald starts to scab the next day, the superficial second degree scald heals within 7 days, and the deep second degree scald heals within 2 weeks.

The effect is shown: pain is obviously relieved on the day of medication, exudation is reduced, and first degree scald starts to scab the next day, superficial second degree scald forms scab within 7 days, and deep second degree scald forms scab within 2 weeks.

And (4) invalidation: the above standard is not met.

(4) The treatment results are as follows: (see Table 1 below)

The results in table 1 show that the scald medicine prepared by the invention can effectively treat scalds, the cure rate reaches 100%, and the treatment effect is superior to that of the commercially available scald ointment.

The external-use soaking cold compress liquid for burns and scalds is proved to have obvious curative effect through actual treatment and use of a plurality of patients. The following list of partial treatment cases:

case 1: certain of plum, male, age 34; the palm of the right hand is scalded by the iron block welded by electric welding in 6 months in 2020, the palm skin tissue of the standing horse is separated and is accompanied by the appearance of blisters, the burn is diagnosed as the initial stage of the burn, the wound is soaked in time by the electric welding is used for the palm, the electric welding electric.

Case 2: shen somewhere, woman, 56 years old; the right shank and instep are scalded by boiled water, from superficial II to deep II. The scalded part is soaked in large flaky water. The wound is not treated in time after being injured, and when the doctor visits the patient 2 days later, the local wound is festered, accompanied by strong pain, and seepage flows out, so that the patient is diagnosed as the middle stage of scald; when the invention is used for soaking the wound for 2 hours, the pain sense disappears in the soaking process. The wound is encrusted in the same day, and can be healed after being continuously soaked for 3 times and 7 days without scar left.

Case 3: when a certain person is aged for 12 years, the left arm of the person is scalded by hot oil in 2018 and 9 months, the scalded person is simply smeared with certain scalding oil, but the part is hot, red and swollen and is accompanied with painful bubble swelling. After that, the scald oil is not used and is soaked by the scald oil, the pain feeling disappears in the soaking process, the red and swollen bubbles obviously disappear after 2 hours, no obvious pain bubbles appear in the bubbles in the next day, and no scar is left after 7 days when new skin grows out.

Case 4: in a certain week, male, age 29, in 2021 month, the face is bruised by chunley gunpowder, so that a large area of gunpowder burns from the left eyelid to the left lower jaw and the right eyelid, then a little star blister is raised in the standing horse, the whole face is obviously edematous, severe face burn is diagnosed, the liquid medicine is applied by cold compress with a towel in time, the towel is placed in the liquid medicine for liquid change at an interval of about 30 minutes midway, the towel with strong adsorption is directly applied to sleep at night, so that obvious scabbing appears in the second day after cold compress is carried out for one night, a new skin grows and is accompanied with molting in the third day, the male heals after 7 days, and the whole burned part is completely changed into the new skin without scars.

Case 5: somebody, woman, 36 years old. When cooking, hot oil is carelessly sprayed on the arms and the backs of the hands, and then rash and blood bubbles appear. The patients do not see a diagnosis in the same day, and are treated by self-pouring cold water and smearing commercially available scald ointment, and no improvement is seen. The next day, the patients are diagnosed, the skin on the surface of the wound surface is black purple, and pus exudation appears to show necrotic tissues. The cold compress of the invention is directly applied, after 2 hours of cold compress, the local red and swollen part is changed from dark color to light color, the blood bubbles of the wound surface disappear, and the wound surface is gradually dried and the area is reduced after two days of cold compress. After 7 days, the wound surface is basically healed without leaving scars.

In conclusion, the externally-used soaking cold compress liquid for burns and scalds has a good treatment effect on burns and scalds, raw materials required for preparation are easy to obtain, the preparation method is simple, good news can be brought to the treatment of burn and scald patients through large-scale popularization and use, and a high social value can be generated.

Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims

1. The externally-applied soaking cold compress liquid for burns and scalds is characterized by being prepared from the following raw materials in parts by weight: 0.5 part of rock candy, 5-10 parts of mint, 5-10 parts of yellow chrysanthemum, 5-10 parts of rose, 5-10 parts of dandelion, 15-20 parts of radix sophorae flavescentis, 5-10 parts of phellodendron, 10-15 parts of groundsel, 5-10 parts of clove, 5-8 parts of borneol, 5-10 parts of fructus cnidii, 5-10 parts of radix stemonae, 0.03-0.05 part of chlorhexidine acetate solution, and 5-15 parts of ganoderma lucidum water and 10-15 parts of spring water which are used as bases of cold compress liquid.

2. The externally-used soaking cold compress liquid for burns and scalds as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight: 0.5 part of rock candy, 5 parts of mint, 5 parts of yellow chrysanthemum, 5 parts of rose, 5 parts of dandelion, 15 parts of sophora flavescens, 5 parts of golden cypress, 10 parts of groundsel, 5 parts of clove, 5 parts of borneol, 5 parts of fructus cnidii, 5 parts of radix stemonae, 0.03 part of chlorhexidine acetate solution, and 10 parts of ganoderma lucidum water and spring water which are used as bases of cold compress liquid.

3. The externally-used soaking cold compress liquid for burns and scalds as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight: 0.5 part of rock candy, 10 parts of mint, 10 parts of yellow chrysanthemum, 10 parts of rose, 10 parts of dandelion, 20 parts of radix sophorae flavescentis, 10 parts of golden cypress, 15 parts of groundsel, 10 parts of clove, 8 parts of borneol, 10 parts of fructus cnidii, 10 parts of radix stemonae, 0.05 part of chlorhexidine acetate solution, and 15 parts of ganoderma lucidum water and 15 parts of spring water which are used as bases of cold compress liquid.

4. The externally-used soaking cold compress liquid for burns and scalds as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight: 0.5 part of rock candy, 8 parts of mint, 8 parts of yellow chrysanthemum, 8 parts of rose, 8 parts of dandelion, 17 parts of sophora flavescens, 8 parts of golden cypress, 12 parts of groundsel, 7 parts of clove, 6 parts of borneol, 8 parts of fructus cnidii, 8 parts of radix stemonae, 0.04 part of chlorhexidine acetate solution, and 12 parts of ganoderma lucidum water and spring water which are used as bases of cold compress liquid.

5. The preparation method of the externally used soaking cold compress liquid for burns and scalds according to any one of claims 1 to 4, which is characterized by comprising the following steps: