CN105748841B - Medicine for treating burns and scalds and preventing scar formation after healing and preparation method thereof - Google Patents

Medicine for treating burns and scalds and preventing scar formation after healing and preparation method thereof Download PDF

Info

Publication number
CN105748841B
CN105748841B CN201610198217.7A CN201610198217A CN105748841B CN 105748841 B CN105748841 B CN 105748841B CN 201610198217 A CN201610198217 A CN 201610198217A CN 105748841 B CN105748841 B CN 105748841B
Authority
CN
China
Prior art keywords
parts
prepared
blood
medicine
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201610198217.7A
Other languages
Chinese (zh)
Other versions
CN105748841A (en
Inventor
苏一康
苏跃峰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ZHENGZHOU MILI PHARMACEUTICAL CO Ltd
Original Assignee
ZHENGZHOU MILI PHARMACEUTICAL CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ZHENGZHOU MILI PHARMACEUTICAL CO Ltd filed Critical ZHENGZHOU MILI PHARMACEUTICAL CO Ltd
Priority to CN201610198217.7A priority Critical patent/CN105748841B/en
Publication of CN105748841A publication Critical patent/CN105748841A/en
Application granted granted Critical
Publication of CN105748841B publication Critical patent/CN105748841B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biomedical Technology (AREA)
  • Insects & Arthropods (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Animal Husbandry (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to the field of medicine, in particular to a medicine which takes a plurality of Chinese medicinal materials as raw materials, is safe and reliable, has no stimulation, obvious effect and definite curative effect, has the functions of treating burns and scalds and preventing scar formation after healing and a preparation method thereof.

Description

Medicine for treating burns and scalds and preventing scar formation after healing and preparation method thereof
Technical Field
The invention relates to the field of medicines, in particular to a medicine which takes a plurality of traditional Chinese medicinal materials as raw materials, is safe and reliable, has no stimulation, obvious effect and definite curative effect, has the functions of treating burns and scalds and preventing scar formation after healing, and a preparation method thereof.
Background
The burns and scalds caused by various reasons in daily life and work of people cause the pain of the skin of the body, and lead to the serious physical and mental disability, thereby not only bringing about the pain and economic loss to families, but also causing certain influence to the society. Although various treatment methods exist in the modern Chinese and western medicine, the modern Chinese and western medicine is not ideal, and no ideal medicine is available for curing burns and scalds and simultaneously leaving no scars. Because of the limitations of treatment methods and effects, a great number of burn and scald patients suffer from pain and even risk of disability every year in medical units. The invention is based on the theory of traditional Chinese medicine, conforms to the treatment rules of promoting blood circulation to remove blood stasis, promoting granulation and relieving pain, reducing swelling and preventing corrosion, and expelling toxin and relieving itching, and has positive treatment and rehabilitation effects on treating first-degree and second-degree burns and scalds and preventing the formation of scars after healing.
Disclosure of Invention
The invention aims to overcome the defects of poor curative effect, large side effect, high cost and easy secondary injury to patients in the existing therapy, and provides a medicament which is safe, reliable, non-irritant, low in cost, obvious in effect, exact in curative effect, has treatment and rehabilitation effects on burns and scalds and can prevent scar formation after healing and a preparation method thereof.
The technical scheme of the invention is realized as follows:
a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 3-5 parts of frankincense, 3-5 parts of prepared myrrh, 3-5 parts of trogopterus dung, 20-30 parts of lithospermum, 3-5 parts of golden cypress, 10-15 parts of coptis chinensis, 3-5 parts of dragon's blood, 3-5 parts of catechu, 3-5 parts of platycladi seed, 20-24 parts of sanguisorba, 10-15 parts of rheum officinale, 10-20 parts of angelica sinensis, 10-20 parts of peach kernel, 6-10 parts of pinecone, 6-10 parts of cornus officinalis, 5-10 parts of borneol and 6-10 parts of beeswax, and the sesame oil also comprises sesame oil, wherein the ratio of the parts by weight of the sesame oil to the sum of the parts by weight of the frankincense, the prepared myrrh, the trogopterus dung, the lithospermum, the phellodendron, the coptis chinensis, the catechu, the dragon's blood, the platycladi seed, the.
Further, the feed is prepared from the following raw materials in parts by weight: 3-5 parts of frankincense, 3-5 parts of prepared myrrh, 3-5 parts of trogopterus dung, 23-27 parts of lithospermum, 3-5 parts of golden cypress, 11-14 parts of coptis chinensis, 3-5 parts of dragon's blood, 3-5 parts of catechu, 3-5 parts of platycladi seed, 21-23 parts of sanguisorba officinalis, 11-14 parts of rheum officinale, 13-17 parts of angelica sinensis, 13-17 parts of peach kernel, 7-9 parts of pinecone, 7-9 parts of cornus officinalis, 6-9 parts of borneol, 7-9 parts of beewax, and sesame oil, wherein the ratio of the parts by weight of the sesame oil to the sum of the parts by weight of the frankincense, the prepared myrrh, the trogopterus dung, the lithospermum, the phellodendron, the coptis chinensis, the catechu, the dragon's blood, the platycladi seed, the sanguisorba.
Specifically, the feed is prepared from the following raw materials in parts by weight: 4 parts of frankincense, 4 parts of prepared myrrh, 4 parts of trogopterus dung, 25 parts of lithospermum, 4 parts of golden cypress, 12 parts of coptis chinensis, 4 parts of dragon's blood, 4 parts of catechu, 4 parts of platycladi seed, 22 parts of garden burnet, 12 parts of rheum officinale, 15 parts of angelica, 15 parts of peach kernel, 8 parts of pinecone, 8 parts of hydrocerussitum, 7 parts of borneol, 8 parts of beewax and sesame oil, wherein the ratio of the parts by weight of the sesame oil to the sum of the parts by weight of the frankincense, the prepared myrrh, the trogopterus dung, the lithospermum, the golden cypress, the coptis chinensis, the dragon's blood, the catechu, the platycladi seed, the garden burnet, the rhe.
A preparation method of a medicine for treating burn and scald and preventing scar formation after healing comprises:
step one), weighing various raw materials according to the weight parts of the raw materials, respectively picking up frankincense, prepared myrrh, trogopterus dung, lithospermum, phellodendron, coptis chinensis, dragon's blood, catechu, platycladi seed, garden burnet, rhubarb, angelica, peach kernel, pine cone, hydrocerussitum and beeswax, screening and removing impurities;
step two), peeling peach kernels;
step three), putting the frankincense, the prepared myrrh, the trogopterus dung, the lithospermum, the golden cypress, the coptis chinensis, the dragon's blood, the catechu, the platycladi seed, the garden burnet, the rhubarb, the Chinese angelica, the peach kernel and the pine cone which are processed in the step one) and the step two) into a pot, and soaking the mixture for eight hours by using sesame oil;
step four), after soaking, frying the mixture to be brown with slow fire to obtain dregs of a decoction, fishing out the dregs of a decoction, filtering the dregs of a decoction with 3-4 layers of gauze, and performing oil draining treatment to obtain a liquid medicine remaining in the pot;
step five), decocting the liquid medicine left in the step four) for 1.5 hours by slow fire;
step six), cooling the temperature of the liquid medicine obtained in the step five) to 70 ℃, sequentially and respectively placing the cerbroussa, the borneol and the beeswax into a pot for stirring treatment, continuously stirring by using a locust tree shovel in the process, and stirring into paste;
step seven), cooling the temperature of the pasty medicine obtained in the step six) to room temperature to obtain paste, inspecting the obtained paste and encapsulating the paste in a rubber tube or other packaging materials.
The invention has the positive effects that:
the traditional Chinese medicine composition is reasonable in compatibility of medicines, is prepared by a reasonable medicine processing method, has stable medicine effect, quick drug action, convenient use, quick response, short treatment course and obvious curative effect, can promote the absorption of pathological products and inflammatory exudates, improves the microcirculation of the skin of an affected part, recovers the elasticity of the skin of the affected part and eliminates pigmentation. Has effects of promoting blood circulation, removing blood stasis, removing toxic substance, astringing, promoting granulation, and dispersing pathogen accumulation, and can be used for stimulating new skin growth and moistening skin. Has the advantages of simple preparation process, no toxic or side effect, convenient use and the like, can relieve the pain of burn and scald patients, meet the requirements of medical care and beauty treatment, can be used for treating the burn and scald caused by various reasons and has the effect of preventing the scar from forming after healing.
The invention has no toxic and side effect, and the pharmacology of the adopted medicines in the formula is as follows: the frankincense is pungent and bitter in taste and warm in nature, has the effects of promoting blood circulation to relieve pain, diminishing swelling and promoting granulation, mainly treats traumatic injury and qi and blood stasis, treats myrrh, is bitter and pungent in taste, is neutral in nature and non-toxic, mainly treats the traumatic injury, has good effects of treating wounds and skin inflammation, has the effects of dissipating blood stasis and relieving pain, diminishing swelling and promoting granulation and the like, and can promote blood circulation to remove blood stasis, enhance blood circulation on the surface of skin, promote wound healing and generate new skin; trogopterus dung is bitter, sweet and warm in nature and taste, can promote blood circulation to relieve pain, is charred to stop bleeding, and is externally used for treating traumatic injury; the lithospermum has sweet, salty and cold nature and taste, and has the effects of clearing heat, cooling blood, promoting blood circulation, detoxifying, promoting eruption, removing ecchymoses and the like; cortex Phellodendri, bitter and cold in nature, has effects of clearing heat and eliminating dampness, purging fire and removing heat, removing toxic substance and treating sore, diminishing inflammation, relieving pain and promoting local blood circulation to improve microcirculation, continuously supply sufficient nutrition to wound surface, improve immunity and anti-infection ability, and can promote local cell metabolism and absorb extravasated tissue fluid when used externally; the coptis chinensis is bitter in taste and cold in nature, clears heat and dampness, purges fire and detoxifies, and can be used for treating soup fire scalds; dragon's blood, neutral in nature, sweet in taste, salty in flavor, has the effects of promoting blood circulation, relieving pain, removing blood stasis, stopping bleeding, healing sore, promoting granulation and the like, and is mainly used for treating traumatic injury, stasis, heart and abdomen pain, traumatic hemorrhage, unhealed sores and ulcers and the like; catechu, bitter and astringent in nature and taste, slightly cold, has effects of promoting blood circulation, relieving pain, arresting bleeding, promoting granulation, astringing dampness and healing sore; semen Platycladi has sweet taste and mild property, and has effects of nourishing heart, tranquilizing mind, loosening bowel to relieve constipation, and can be used for treating yin blood deficiency; the sanguisorba officinalis has the effects of cooling blood, stopping bleeding, detoxifying, healing sores and treating burns and scalds due to water and fire; rhubarb, bitter in nature and cold in taste, has the effects of removing food retention, clearing heat, purging fire, cooling blood, removing blood stasis, detoxifying and the like, and is externally used for treating burns and scalds; the angelica has sweet, pungent and warm nature and flavor, and has the effects of enriching blood, promoting blood circulation, regulating menstruation, relieving pain and treating traumatic injury; peach kernel, bitter and sweet, neutral in nature and non-toxic, has the effects of activating blood circulation to dissipate blood stasis, relaxing bowel, treating traumatic injury and the like, and can promote carbuncle swelling and scar softening and dissipation; the pine cone is bitter in taste, warm in nature and non-toxic, and mainly treats intestinal dryness, difficult defecation and wind arthralgia; the powder has effects of resolving food stagnation, removing toxic substance, promoting granulation, eliminating dampness and relieving itching; borneol, pungent and bitter in flavor, slightly cold in nature, unblocks orifices, dispels stagnated fire, treats acne toxin invagination, kills parasites, and also can promote granulation and relieve pain; beeswax, sweet and mild in nature and taste, astringent, capable of healing sore, promoting granulation, relieving pain and conditioning, and is externally used for treating unhealed ulcer, ecthyma erosion, wound, burn and scald; sesame oil is sweet in nature and cool in flavor, and has the effects of generating muscles, relieving pain, eliminating carbuncle and swelling and tonifying skin cracks when being used for decocting a plaster.
The traditional Chinese medicine composition has the advantages of comprehensive prescription and reasonable compatibility of medicines, has the effects of promoting blood circulation to remove blood stasis, softening hardness to eliminate stagnation, promoting granulation to dissipate stagnation, relieving pain and relieving itching, can be used for treating burns and scalds caused by various reasons, and has the effect of preventing scar formation after healing.
The beneficial effects of the present invention are illustrated below in connection with clinical use data:
clinical validation reports of the present invention are as follows:
(one), purpose: in order to carry out expanded verification on the invention, the effect, safety and adverse reaction of the invention can be exactly known, and a conclusion can be made.
(II) case selection:
1. indications are as follows: can be used for treating first degree burn and second degree burn and scald.
2. Diagnostic criteria:
(1) and patients with first-degree and second-degree burn and scald.
3. Inclusion criteria were:
(1) it is not limited to age, and is suitable for both children and adults.
(III) observing curative effect:
1. change of the color of the wound surface; 2. changes in inflammatory exudates; 3. change in scabbing. 4. A change in the degree of pain; 5. the change of itching relieving condition.
(IV) a clinical observation method:
1. in clinical test, 3 test units are determined in the clinical test, the number of each unit is not less than 40, 30 cases of treatment groups and 10 cases of control groups, and a test subject is divided into a test group and a control group.
2. The medication method comprises the following steps: the medicine is used for 2-3 times every day, and the ointment is directly applied to the affected part by using a sterilized cotton swab without binding and exposed for treatment, wherein one week is a treatment course continuously. One to two treatment courses are continuously observed according to the disease condition as the judgment of the curative effect.
(V) treatment effect judgment standard:
1. the effect is shown: after the burn and scald are cured, the crust peels off without obvious scars;
2. the method has the following advantages: after the burn and scald treatment, the crust skin does not completely fall off, the phenomenon of dull red exists, the itching feeling disappears, the crust skin falls off after two weeks, and no obvious scar is left;
3. and (4) invalidation: the symptoms do not change much after one course of treatment.
(VI) test results:
Figure DEST_PATH_IMAGE002
selection of cases: 90 patients with burns and scalds are treated, wherein 56 patients are male, and 34 patients are female; the age is 3-60 years, wherein 47 adults and 43 children are selected; the burn and scald 128 parts of 39 patients with burn, 51 patients with scald and 90 patients with scald commonly occur, wherein the parts of the face 41, the limbs 68 and other parts 19. The patients in this group were all burns and scalds.
Control group 10, male 6 and female 4. 8 patients with scald and 2 patients with burn.
The cure rate and the effective rate are as follows:
and (4) counting results: after the traditional Chinese medicine ointment provided by the invention is applied to patients with burns and scalds, the pain is relieved for 20-30 minutes generally, the scabs are formed after one week, and the scabs fall off after two weeks without scars. The invention provides an effective treatment medicament for clinic (the total effective rate is 95.6 percent), which is obviously superior to the contrast treatment.
Detailed Description
Example 1: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 30 g of frankincense, 30 g of prepared myrrh, 30 g of trogopterus dung, 200 g of lithospermum, 30 g of phellodendron, 100 g of coptis, 30 g of dragon's blood, 30 g of catechu, 30 g of platycladi seed, 200 g of garden burnet, 100 g of rhubarb, 100 g of angelica, 100 g of peach kernel, 60 g of pinecone, 60 g of cerbroussa, 50 g of borneol, 60 g of beeswax and 3100 g of sesame oil.
The preparation method of the medicine for treating burns and scalds and preventing scar formation after healing comprises the following steps:
step one), weighing various raw materials according to the weight requirements of the raw materials, respectively picking up frankincense, prepared myrrh, trogopterus dung, lithospermum, phellodendron, coptis chinensis, dragon's blood, catechu, platycladi seed, garden burnet, rhubarb, angelica, peach kernel, pine cone, hydrocerussitum and beeswax, screening and removing impurities;
step two), peeling peach kernels;
step three), putting the frankincense, the prepared myrrh, the trogopterus dung, the lithospermum, the golden cypress, the coptis chinensis, the dragon's blood, the catechu, the platycladi seed, the garden burnet, the rhubarb, the Chinese angelica, the peach kernel and the pine cone which are processed in the step one) and the step two) into a pot, and soaking the mixture for eight hours by using sesame oil;
step four), after soaking, frying the mixture to be brown with slow fire to obtain dregs of a decoction, filtering the dregs of a decoction with 3-4 layers of gauze, and performing oil draining treatment to obtain liquid medicine remaining in the pot;
step five), decocting the liquid medicine left in the step four) for 1.5 hours by slow fire;
step six), cooling the temperature of the liquid medicine obtained in the step five) to 70 ℃, sequentially and respectively placing the cerbroussa, the borneol and the beeswax into a pot for stirring treatment, continuously stirring by using a locust tree shovel in the process, and stirring into paste;
step seven), cooling the temperature of the pasty medicine obtained in the step six) to room temperature to obtain paste, inspecting the obtained paste and encapsulating the paste in a rubber tube or other packaging materials.
Example 2: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 30 g of frankincense, 35 g of prepared myrrh, 35 g of trogopterus dung, 225 g of lithospermum, 35 g of phellodendron, 110 g of coptis, 35 g of dragon's blood, 35 g of catechu, 35 g of platycladi seed, 210 g of garden burnet root, 110 g of rhubarb, 125 g of angelica, 125 g of peach kernel, 70 g of pine cone, 70 g of official powder, 60 g of borneol, 70 g of beeswax and 3537.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 3: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 30 g of frankincense, 40 g of prepared myrrh, 40 g of trogopterus dung, 250 g of lithospermum, 40 g of phellodendron, 120 g of coptis, 40 g of dragon's blood, 40 g of catechu, 40 g of platycladi seed, 220 g of sanguisorba, 120 g of rhubarb, 150 g of angelica, 150 g of peach kernel, 80 g of pine cone, 80 g of official powder, 70 g of borneol, 80 g of beeswax and 3975 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 4: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 30 g of frankincense, 45 g of prepared myrrh, 45 g of trogopterus dung, 275 g of lithospermum, 45 g of phellodendron, 130 g of coptis chinensis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of cerbroussa, 80 g of borneol, 90 g of beeswax and 4437.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 5: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 30 g of frankincense, 50 g of prepared myrrh, 50 g of trogopterus dung, 300 g of lithospermum, 50 g of phellodendron, 150 g of coptis, 50 g of dragon's blood, 50 g of catechu, 50 g of platycladi seed, 240 g of garden burnet root, 150 g of rhubarb, 200 g of angelica, 200 g of peach kernel, 100 g of pine cone, 100 g of official powder, 100 g of borneol, 100 g of beeswax and 4925 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 6: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 35 g of frankincense, 30 g of prepared myrrh, 30 g of trogopterus dung, 200 g of lithospermum, 30 g of phellodendron, 100 g of coptis chinensis, 30 g of dragon's blood, 30 g of catechu, 30 g of platycladi seed, 200 g of garden burnet, 100 g of rhubarb, 100 g of angelica, 100 g of peach kernel, 60 g of pine cone, 60 g of cerbroussa, 50 g of borneol, 60 g of beeswax and 3112.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 7: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 35 g of frankincense, 35 g of prepared myrrh, 35 g of trogopterus dung, 225 g of lithospermum, 35 g of phellodendron, 110 g of coptis chinensis, 35 g of dragon's blood, 35 g of catechu, 35 g of platycladi seed, 210 g of garden burnet root, 110 g of rhubarb, 125 g of angelica, 125 g of peach kernel, 70 g of pine cone, 70 g of official powder, 60 g of borneol, 70 g of beeswax and 3550 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 8: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 35 g of frankincense, 40 g of prepared myrrh, 40 g of trogopterus dung, 250 g of lithospermum, 40 g of phellodendron, 120 g of coptis, 40 g of dragon's blood, 40 g of catechu, 40 g of platycladi seed, 220 g of sanguisorba, 120 g of rhubarb, 150 g of angelica, 150 g of peach kernel, 80 g of pine cone, 80 g of cerbroussa, 70 g of borneol, 80 g of beeswax and 3987.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 9: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 35 g of frankincense, 45 g of prepared myrrh, 45 g of trogopterus dung, 275 g of lithospermum, 45 g of golden cypress, 130 g of coptis chinensis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of official powder, 80 g of borneol, 90 g of beeswax and 4450 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 10: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 35 g of frankincense, 50 g of prepared myrrh, 50 g of trogopterus dung, 300 g of lithospermum, 50 g of phellodendron, 150 g of coptis chinensis, 50 g of dragon's blood, 50 g of catechu, 50 g of platycladi seed, 240 g of garden burnet root, 150 g of rhubarb, 200 g of angelica, 200 g of peach kernel, 100 g of pine cone, 100 g of official powder, 100 g of borneol, 100 g of beeswax and 4937.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 11: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 40 g of frankincense, 30 g of prepared myrrh, 30 g of trogopterus dung, 200 g of lithospermum, 30 g of phellodendron, 100 g of coptis, 30 g of dragon's blood, 30 g of catechu, 30 g of platycladi seed, 200 g of garden burnet, 100 g of rhubarb, 100 g of angelica, 100 g of peach kernel, 60 g of pinecone, 60 g of cerbroussa, 50 g of borneol, 60 g of beeswax and 3125 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 12: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 40 g of frankincense, 35 g of prepared myrrh, 35 g of trogopterus dung, 225 g of lithospermum, 35 g of phellodendron, 110 g of coptis, 35 g of dragon's blood, 35 g of catechu, 35 g of platycladi seed, 210 g of garden burnet root, 110 g of rhubarb, 125 g of angelica, 125 g of peach kernel, 70 g of pine cone, 70 g of official powder, 60 g of borneol, 70 g of beeswax and 3562.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 13: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 40 g of frankincense, 40 g of prepared myrrh, 40 g of trogopterus dung, 250 g of lithospermum, 40 g of phellodendron, 120 g of coptis, 40 g of dragon's blood, 40 g of catechu, 40 g of platycladi seed, 220 g of sanguisorba, 120 g of rhubarb, 150 g of angelica, 150 g of peach kernel, 80 g of pine cone, 80 g of cerbroussa, 70 g of borneol, 80 g of beeswax and 4000 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 14: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 40 g of frankincense, 45 g of prepared myrrh, 45 g of trogopterus dung, 275 g of lithospermum, 45 g of phellodendron, 130 g of coptis chinensis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of cerbroussa, 80 g of borneol, 90 g of beeswax and 4462.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 15: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 40 g of frankincense, 50 g of prepared myrrh, 50 g of trogopterus dung, 300 g of lithospermum, 50 g of phellodendron, 150 g of coptis, 50 g of dragon's blood, 50 g of catechu, 50 g of platycladi seed, 240 g of garden burnet root, 150 g of rhubarb, 200 g of angelica, 200 g of peach kernel, 100 g of pine cone, 100 g of official powder, 100 g of borneol, 100 g of beeswax and 4950 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 16: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 30 g of prepared myrrh, 30 g of trogopterus dung, 200 g of lithospermum, 30 g of phellodendron, 100 g of coptis, 30 g of dragon's blood, 30 g of catechu, 30 g of platycladi seed, 200 g of garden burnet, 100 g of rhubarb, 100 g of angelica, 100 g of peach kernel, 60 g of pine cone, 60 g of cerbroussa, 50 g of borneol, 60 g of beeswax and 3137.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 17: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 35 g of prepared myrrh, 35 g of trogopterus dung, 225 g of lithospermum, 35 g of phellodendron, 110 g of coptis chinensis, 35 g of dragon's blood, 35 g of catechu, 35 g of platycladi seed, 210 g of garden burnet root, 110 g of rhubarb, 125 g of angelica, 125 g of peach kernel, 70 g of pine cone, 70 g of official powder, 60 g of borneol, 70 g of beeswax and 3575 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 18: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 40 g of prepared myrrh, 40 g of trogopterus dung, 250 g of lithospermum, 40 g of phellodendron, 120 g of coptis, 40 g of dragon's blood, 40 g of catechu, 40 g of platycladi seed, 220 g of garden burnet root, 120 g of rhubarb, 150 g of angelica, 150 g of peach kernel, 80 g of pine cone, 80 g of official powder, 70 g of borneol, 80 g of beeswax and 4012.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 19: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 45 g of prepared myrrh, 45 g of trogopterus dung, 275 g of lithospermum, 45 g of golden cypress, 130 g of coptis chinensis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of official powder, 80 g of borneol, 90 g of beeswax and 4475 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 20: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 50 g of prepared myrrh, 50 g of trogopterus dung, 300 g of lithospermum, 50 g of phellodendron, 150 g of coptis, 50 g of dragon's blood, 50 g of catechu, 50 g of platycladi seed, 240 g of garden burnet root, 150 g of rhubarb, 200 g of angelica, 200 g of peach kernel, 100 g of pine cone, 100 g of official powder, 100 g of borneol, 100 g of beeswax and 4962.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 21: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 50 g of frankincense, 30 g of prepared myrrh, 30 g of trogopterus dung, 200 g of lithospermum, 30 g of phellodendron, 100 g of coptis, 30 g of dragon's blood, 30 g of catechu, 30 g of platycladi seed, 200 g of garden burnet, 100 g of rhubarb, 100 g of angelica, 100 g of peach kernel, 60 g of pine cone, 60 g of cerbroussa, 50 g of borneol, 60 g of beeswax and 3150 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 22: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 50 g of frankincense, 35 g of prepared myrrh, 35 g of trogopterus dung, 225 g of lithospermum, 35 g of phellodendron, 110 g of coptis, 35 g of dragon's blood, 35 g of catechu, 35 g of platycladi seed, 210 g of garden burnet root, 110 g of rhubarb, 125 g of angelica, 125 g of peach kernel, 70 g of pine cone, 70 g of official powder, 60 g of borneol, 70 g of beeswax and 3587.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 23: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 50 g of frankincense, 40 g of prepared myrrh, 40 g of trogopterus dung, 250 g of lithospermum, 40 g of phellodendron, 120 g of coptis, 40 g of dragon's blood, 40 g of catechu, 40 g of platycladi seed, 220 g of sanguisorba, 120 g of rhubarb, 150 g of angelica, 150 g of peach kernel, 80 g of pine cone, 80 g of official powder, 70 g of borneol, 80 g of beeswax and 4025 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 24: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 50 g of frankincense, 45 g of prepared myrrh, 45 g of trogopterus dung, 275 g of lithospermum, 45 g of phellodendron, 130 g of coptis chinensis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of cerbroussa, 80 g of borneol, 90 g of beeswax and 4487.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 25: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 50 g of frankincense, 50 g of prepared myrrh, 50 g of trogopterus dung, 300 g of lithospermum, 50 g of phellodendron, 150 g of coptis, 50 g of dragon's blood, 50 g of catechu, 50 g of platycladi seed, 240 g of garden burnet root, 150 g of rhubarb, 200 g of angelica, 200 g of peach kernel, 100 g of pine cone, 100 g of official powder, 100 g of borneol, 100 g of beeswax and 4975 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 26: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 35 g of frankincense, 30 g of prepared myrrh, 35 g of trogopterus dung, 225 g of lithospermum, 35 g of phellodendron, 110 g of coptis, 35 g of dragon's blood, 35 g of catechu, 35 g of platycladi seed, 210 g of garden burnet root, 110 g of rhubarb, 125 g of angelica, 125 g of peach kernel, 70 g of pine cone, 70 g of official powder, 60 g of borneol, 70 g of beeswax and 3537.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 27: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 40 g of frankincense, 30 g of prepared myrrh, 40 g of trogopterus dung, 250 g of lithospermum, 40 g of phellodendron, 120 g of coptis, 40 g of dragon's blood, 40 g of catechu, 40 g of platycladi seed, 220 g of sanguisorba, 120 g of rhubarb, 150 g of angelica, 150 g of peach kernel, 80 g of pine cone, 80 g of official powder, 70 g of borneol, 80 g of beeswax and 3975 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 28: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 30 g of prepared myrrh, 45 g of trogopterus dung, 275 g of lithospermum, 45 g of phellodendron, 130 g of coptis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of cerbroussa, 80 g of borneol, 90 g of beeswax and 4437.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 29: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 50 g of frankincense, 30 g of prepared myrrh, 50 g of trogopterus dung, 300 g of lithospermum, 50 g of phellodendron, 150 g of coptis, 50 g of dragon's blood, 50 g of catechu, 50 g of platycladi seed, 240 g of garden burnet root, 150 g of rhubarb, 200 g of angelica, 200 g of peach kernel, 100 g of pine cone, 100 g of official powder, 100 g of borneol, 100 g of beeswax and 4925 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 30: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 30 g of frankincense, 35 g of prepared myrrh, 30 g of trogopterus dung, 200 g of lithospermum, 30 g of phellodendron, 100 g of coptis chinensis, 30 g of dragon's blood, 30 g of catechu, 30 g of platycladi seed, 200 g of garden burnet, 100 g of rhubarb, 100 g of angelica, 100 g of peach kernel, 60 g of pine cone, 60 g of cerbroussa, 50 g of borneol, 60 g of beeswax and 3112.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 31: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 40 g of frankincense, 35 g of prepared myrrh, 40 g of trogopterus dung, 250 g of lithospermum, 40 g of phellodendron, 120 g of coptis, 40 g of dragon's blood, 40 g of catechu, 40 g of platycladi seed, 220 g of sanguisorba, 120 g of rhubarb, 150 g of angelica, 150 g of peach kernel, 80 g of pine cone, 80 g of cerbroussa, 70 g of borneol, 80 g of beeswax and 3987.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 32: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 35 g of prepared myrrh, 45 g of trogopterus dung, 275 g of lithospermum, 45 g of golden cypress, 130 g of coptis chinensis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of official powder, 80 g of borneol, 90 g of beeswax and 4450 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 33: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 50 g of frankincense, 35 g of prepared myrrh, 50 g of trogopterus dung, 300 g of lithospermum, 50 g of phellodendron, 150 g of coptis chinensis, 50 g of dragon's blood, 50 g of catechu, 50 g of platycladi seed, 240 g of garden burnet root, 150 g of rhubarb, 200 g of angelica, 200 g of peach kernel, 100 g of pine cone, 100 g of official powder, 100 g of borneol, 100 g of beeswax and 4937.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 34: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 30 g of frankincense, 40 g of prepared myrrh, 30 g of trogopterus dung, 200 g of lithospermum, 30 g of phellodendron, 100 g of coptis, 30 g of dragon's blood, 30 g of catechu, 30 g of platycladi seed, 200 g of garden burnet, 100 g of rhubarb, 100 g of angelica, 100 g of peach kernel, 60 g of pinecone, 60 g of cerbroussa, 50 g of borneol, 60 g of beeswax and 3125 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 35: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 35 g of frankincense, 40 g of prepared myrrh, 35 g of trogopterus dung, 225 g of lithospermum, 35 g of phellodendron, 110 g of coptis, 35 g of dragon's blood, 35 g of catechu, 35 g of platycladi seed, 210 g of garden burnet root, 110 g of rhubarb, 125 g of angelica, 125 g of peach kernel, 70 g of pine cone, 70 g of official powder, 60 g of borneol, 70 g of beeswax and 3562.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 36: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 40 g of prepared myrrh, 45 g of trogopterus dung, 275 g of lithospermum, 45 g of phellodendron, 130 g of coptis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of cerbroussa, 80 g of borneol, 90 g of beeswax and 4462.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 37: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 50 g of frankincense, 40 g of prepared myrrh, 50 g of trogopterus dung, 300 g of lithospermum, 50 g of phellodendron, 150 g of coptis, 50 g of dragon's blood, 50 g of catechu, 50 g of platycladi seed, 240 g of garden burnet root, 150 g of rhubarb, 200 g of angelica, 200 g of peach kernel, 100 g of pine cone, 100 g of official powder, 100 g of borneol, 100 g of beeswax and 4950 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 38: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 30 g of frankincense, 50 g of prepared myrrh, 30 g of trogopterus dung, 200 g of lithospermum, 30 g of phellodendron, 100 g of coptis, 30 g of dragon's blood, 30 g of catechu, 30 g of platycladi seed, 200 g of garden burnet, 100 g of rhubarb, 100 g of angelica, 100 g of peach kernel, 60 g of pine cone, 60 g of cerbroussa, 50 g of borneol, 60 g of beeswax and 3150 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 39: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 35 g of frankincense, 50 g of prepared myrrh, 35 g of trogopterus dung, 225 g of lithospermum, 35 g of phellodendron, 110 g of coptis, 35 g of dragon's blood, 35 g of catechu, 35 g of platycladi seed, 210 g of garden burnet root, 110 g of rhubarb, 125 g of angelica, 125 g of peach kernel, 70 g of pine cone, 70 g of official powder, 60 g of borneol, 70 g of beeswax and 3587.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 40: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 40 g of frankincense, 50 g of prepared myrrh, 40 g of trogopterus dung, 250 g of lithospermum, 40 g of phellodendron, 120 g of coptis, 40 g of dragon's blood, 40 g of catechu, 40 g of platycladi seed, 220 g of sanguisorba, 120 g of rhubarb, 150 g of angelica, 150 g of peach kernel, 80 g of pine cone, 80 g of official powder, 70 g of borneol, 80 g of beewax and 4025 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 41: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 50 g of prepared myrrh, 45 g of trogopterus dung, 275 g of lithospermum, 45 g of phellodendron, 130 g of coptis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of cerbroussa, 80 g of borneol, 90 g of beeswax and 4487.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 42: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 35 g of frankincense, 35 g of prepared myrrh, 35 g of trogopterus dung, 200 g of lithospermum, 35 g of phellodendron, 110 g of coptis, 35 g of dragon's blood, 35 g of catechu, 35 g of platycladi seed, 210 g of garden burnet root, 110 g of rhubarb, 125 g of angelica, 125 g of peach kernel, 70 g of pine cone, 70 g of official powder, 60 g of borneol, 70 g of beeswax and 3487.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 43: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 40 g of frankincense, 40 g of prepared myrrh, 40 g of trogopterus dung, 200 g of lithospermum, 40 g of phellodendron, 120 g of coptis, 40 g of dragon's blood, 40 g of catechu, 40 g of platycladi seed, 220 g of sanguisorba, 120 g of rhubarb, 150 g of angelica, 150 g of peach kernel, 80 g of pine cone, 80 g of official powder, 70 g of borneol, 80 g of beeswax and 3875 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 44: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 45 g of prepared myrrh, 45 g of trogopterus dung, 200 g of lithospermum, 45 g of phellodendron, 130 g of coptis chinensis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of cerbroussa, 80 g of borneol, 90 g of beeswax and 4287.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 45: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 50 g of frankincense, 50 g of prepared myrrh, 50 g of trogopterus dung, 200 g of lithospermum, 50 g of phellodendron, 150 g of coptis, 50 g of dragon's blood, 50 g of catechu, 50 g of platycladi seed, 240 g of garden burnet root, 150 g of rhubarb, 200 g of angelica, 200 g of peach kernel, 100 g of pine cone, 100 g of official powder, 100 g of borneol, 100 g of beeswax and 4725 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 46: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 30 g of frankincense, 30 g of prepared myrrh, 30 g of trogopterus dung, 225 g of lithospermum, 30 g of phellodendron, 100 g of coptis chinensis, 30 g of dragon's blood, 30 g of catechu, 30 g of platycladi seed, 200 g of sanguisorba officinalis, 100 g of rhubarb, 100 g of angelica, 100 g of peach kernel, 60 g of pine cone, 60 g of cerbroussa, 50 g of borneol, 60 g of beeswax and 3162.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 47: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 40 g of frankincense, 40 g of prepared myrrh, 40 g of trogopterus dung, 225 g of lithospermum, 40 g of phellodendron, 120 g of coptis, 40 g of dragon's blood, 40 g of catechu, 40 g of platycladi seed, 220 g of sanguisorba, 120 g of rhubarb, 150 g of angelica, 150 g of peach kernel, 80 g of pine cone, 80 g of cerbroussa, 70 g of borneol, 80 g of beeswax and 3937.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 48: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 45 g of prepared myrrh, 45 g of trogopterus dung, 225 g of lithospermum, 45 g of golden cypress, 130 g of coptis chinensis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of official powder, 80 g of borneol, 90 g of beewax and 4350 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 49: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 50 g of frankincense, 50 g of prepared myrrh, 50 g of trogopterus dung, 225 g of lithospermum, 50 g of phellodendron, 150 g of coptis chinensis, 50 g of dragon's blood, 50 g of catechu, 50 g of platycladi seed, 240 g of garden burnet root, 150 g of rhubarb, 200 g of angelica, 200 g of peach kernel, 100 g of pine cone, 100 g of official powder, 100 g of borneol, 100 g of beeswax and 4787.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 50: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 30 g of frankincense, 30 g of prepared myrrh, 30 g of trogopterus dung, 250 g of lithospermum, 30 g of phellodendron, 100 g of coptis, 30 g of dragon's blood, 30 g of catechu, 30 g of platycladi seed, 200 g of sanguisorba, 100 g of rhubarb, 100 g of angelica, 100 g of peach kernel, 60 g of pine cone, 60 g of cerbroussa, 50 g of borneol, 60 g of beeswax and 3225 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 51: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 35 g of frankincense, 35 g of prepared myrrh, 35 g of trogopterus dung, 250 g of lithospermum, 35 g of phellodendron, 110 g of coptis, 35 g of dragon's blood, 35 g of catechu, 35 g of platycladi seed, 210 g of garden burnet root, 110 g of rhubarb, 125 g of angelica, 125 g of peach kernel, 70 g of pine cone, 70 g of official powder, 60 g of borneol, 70 g of beeswax and 3612.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 52: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 45 g of frankincense, 45 g of prepared myrrh, 45 g of trogopterus dung, 250 g of lithospermum, 45 g of phellodendron, 130 g of coptis chinensis, 45 g of dragon's blood, 45 g of catechu, 45 g of platycladi seed, 230 g of garden burnet root, 140 g of rhubarb, 175 g of angelica, 175 g of peach kernel, 90 g of pine cone, 90 g of cerbroussa, 80 g of borneol, 90 g of beeswax and 4412.5 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
Example 53: a medicine for treating burns and scalds and preventing scar formation after healing is prepared from the following raw materials in parts by weight: 50 g of frankincense, 50 g of prepared myrrh, 50 g of trogopterus dung, 250 g of lithospermum, 50 g of phellodendron, 150 g of coptis, 50 g of dragon's blood, 50 g of catechu, 50 g of platycladi seed, 240 g of garden burnet root, 150 g of rhubarb, 200 g of angelica, 200 g of peach kernel, 100 g of pine cone, 100 g of official powder, 100 g of borneol, 100 g of beeswax and 4850 g of sesame oil. The subsequent detailed preparation method is identical to example 1 and is not repeated here.
The cases are as follows:
case 1:
a person who is Ma and women who are 36 years old burns due to careless fire caused by frying oil, burns on the face, burns hair, and soaks in different sizes on hands, and the burned skin is sprayed with soy sauce, so that the skin is partially peeled and has intolerable pain, the pain is obviously relieved in less than 30 minutes after the medicine is used, scabbing is realized after 3 days, the person is basically cured in 7 days, and no obvious scar is left.
Case 2:
wangzhi, male, at age 32, carelessly breaks a thermos bottle, burns legs and feet with boiled water, immediately takes off shoes and socks, cuts off trouser legs, finds that the pain is almost unbearable, punctures the bubbles on the legs by a needle, coats the medicine, immediately stops the pain, forms a crust after one week, basically heals after two weeks, and hardly leaves scars.
Case 3:
when people live in 6 years old or four years old, the people drop into a hot water pot carelessly on a cooking bench, and after pulling out the children, the family cuts off the clothes immediately, finds that the face, the hands and the arms all have red skin and blisters, then punctures the blisters with a needle, and stops pain immediately after applying the ointment, and no scar is formed after healing.

Claims (4)

1. The medicine for treating burns and scalds and preventing scar formation after healing is characterized by being prepared from the following raw materials in parts by weight: 3-5 parts of frankincense, 3-5 parts of prepared myrrh, 3-5 parts of trogopterus dung, 20-30 parts of lithospermum, 3-5 parts of golden cypress, 10-15 parts of coptis chinensis, 3-5 parts of dragon's blood, 3-5 parts of catechu, 3-5 parts of platycladi seed, 20-24 parts of sanguisorba, 10-15 parts of rheum officinale, 10-20 parts of angelica sinensis, 10-20 parts of peach kernel, 6-10 parts of pinecone, 6-10 parts of cornus officinalis, 5-10 parts of borneol and 6-10 parts of beeswax, and the sesame oil also comprises sesame oil, wherein the ratio of the parts by weight of the sesame oil to the sum of the parts by weight of the frankincense, the prepared myrrh, the trogopterus dung, the lithospermum, the phellodendron, the coptis chinensis, the catechu, the dragon's blood, the platycladi seed, the.
2. The medicine for treating burns and scalds and preventing scar formation after healing is characterized by being prepared from the following raw materials in parts by weight: 3-5 parts of frankincense, 3-5 parts of prepared myrrh, 3-5 parts of trogopterus dung, 23-27 parts of lithospermum, 3-5 parts of golden cypress, 11-14 parts of coptis chinensis, 3-5 parts of dragon's blood, 3-5 parts of catechu, 3-5 parts of platycladi seed, 21-23 parts of sanguisorba officinalis, 11-14 parts of rheum officinale, 13-17 parts of angelica sinensis, 13-17 parts of peach kernel, 7-9 parts of pinecone, 7-9 parts of cornus officinalis, 6-9 parts of borneol, 7-9 parts of beewax, and sesame oil, wherein the ratio of the parts by weight of the sesame oil to the sum of the parts by weight of the frankincense, the prepared myrrh, the trogopterus dung, the lithospermum, the phellodendron, the coptis chinensis, the catechu, the dragon's blood, the platycladi seed, the sanguisorba.
3. The medicine for treating burns and scalds and preventing scar formation after healing is characterized by being prepared from the following raw materials in parts by weight: 4 parts of frankincense, 4 parts of prepared myrrh, 4 parts of trogopterus dung, 25 parts of lithospermum, 4 parts of golden cypress, 12 parts of coptis chinensis, 4 parts of dragon's blood, 4 parts of catechu, 4 parts of platycladi seed, 22 parts of garden burnet, 12 parts of rheum officinale, 15 parts of angelica, 15 parts of peach kernel, 8 parts of pinecone, 8 parts of hydrocerussitum, 7 parts of borneol, 8 parts of beewax and sesame oil, wherein the ratio of the parts by weight of the sesame oil to the sum of the parts by weight of the frankincense, the prepared myrrh, the trogopterus dung, the lithospermum, the golden cypress, the coptis chinensis, the dragon's blood, the catechu, the platycladi seed, the garden burnet, the rhe.
4. A preparation method of a medicine for treating burns and scalds and preventing scar formation after healing is characterized by comprising the following steps:
step one), weighing various raw materials according to the weight parts of the raw materials in the claims, respectively picking up frankincense, prepared myrrh, trogopterus dung, lithospermum, phellodendron, coptis chinensis, dragon's blood, catechu, platycladi seed, garden burnet, rhubarb, angelica sinensis, peach kernel, pine cone, hydrocerussitum and beeswax, screening and removing impurities;
step two), peeling peach kernels;
step three), putting the frankincense, the prepared myrrh, the trogopterus dung, the lithospermum, the golden cypress, the coptis chinensis, the dragon's blood, the catechu, the platycladi seed, the garden burnet, the rhubarb, the Chinese angelica, the peach kernel and the pine cone which are processed in the step one) and the step two) into a pot, and soaking the mixture for eight hours by using sesame oil;
step four), after soaking, frying the mixture to be brown with slow fire to obtain dregs of a decoction, filtering the dregs of a decoction with 3-4 layers of gauze, and performing oil drying control treatment, wherein the liquid medicine is remained in the pot;
step five), decocting the liquid medicine left in the step four) for 1.5 hours by slow fire;
step six), cooling the temperature of the liquid medicine obtained in the step five) to 70 ℃, sequentially and respectively placing the cerbroussa, the borneol and the beeswax into a pot for stirring treatment, continuously stirring by using a locust tree shovel in the process, and stirring into paste;
step seven), cooling the temperature of the pasty medicine obtained in the step six) to room temperature to obtain paste, inspecting the obtained paste and encapsulating the paste in a rubber tube or other packaging materials.
CN201610198217.7A 2016-04-01 2016-04-01 Medicine for treating burns and scalds and preventing scar formation after healing and preparation method thereof Active CN105748841B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610198217.7A CN105748841B (en) 2016-04-01 2016-04-01 Medicine for treating burns and scalds and preventing scar formation after healing and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610198217.7A CN105748841B (en) 2016-04-01 2016-04-01 Medicine for treating burns and scalds and preventing scar formation after healing and preparation method thereof

Publications (2)

Publication Number Publication Date
CN105748841A CN105748841A (en) 2016-07-13
CN105748841B true CN105748841B (en) 2020-02-14

Family

ID=56346945

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610198217.7A Active CN105748841B (en) 2016-04-01 2016-04-01 Medicine for treating burns and scalds and preventing scar formation after healing and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105748841B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108096409A (en) * 2016-11-23 2018-06-01 雷紫涵 It is a kind of(Quickly)The drug and manufacturing method of scar are stayed in anti-inflammatory myogenic prevention
CN111437324A (en) * 2020-05-29 2020-07-24 司明全 Traditional Chinese medicine formula for treating burns and scalds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102813772B (en) * 2012-08-29 2014-04-09 王永欣 Self-healing ointment for treating burns and preparation method thereof
CN104958544A (en) * 2015-06-15 2015-10-07 侯福刚 Traditional Chinese medicine composition for treating burning and scalding injury and method for manufacturing traditional Chinese medicine composition
CN104984249A (en) * 2015-07-17 2015-10-21 曾德锋 Composition for treating scalds and preparation method thereof
CN105055751A (en) * 2015-08-25 2015-11-18 马千里 Traditional Chinese medicine composition for treating burns and scalds
CN105434870A (en) * 2015-12-24 2016-03-30 张彬彬 Externally used ointment for treating burns and scalds

Also Published As

Publication number Publication date
CN105748841A (en) 2016-07-13

Similar Documents

Publication Publication Date Title
CN104667244B (en) A kind of Pediluvium composition for treating primary dysmenorrhea
CN102125634A (en) Chinese medicinal composition for treating bedsore
CN1199668C (en) Chinese-medicinal ointment for treating burn and scald and its preparing process
CN103239662B (en) Parasite expelling Chinese herbal preparation for animals
CN104984316A (en) Medicine for treating female cold in uterus
CN105748841B (en) Medicine for treating burns and scalds and preventing scar formation after healing and preparation method thereof
CN102961526B (en) Syndromic compound bee-glue composition for the treatment of broiler urate deposition and preparation method thereof
CN104998051A (en) Medicine for treating menstruation delay
CN105213691A (en) A kind of Chinese medicine composition for the treatment of menoxenia
CN102205022B (en) Chinese medicinal preparation for treating mycotic infection and preparation method thereof
CN103977367A (en) Traditional Chinese medicament for treating qi-stagnation blood-aggregation type bedsore and preparation method thereof
CN103212001B (en) Chinese medicinal composition treating diarrhoea
CN104524277A (en) Traditional Chinese medicine mixture for treating anorexia nervosa
CN105596742B (en) A topical Chinese medicinal ointment for treating burn and scald, and its preparation method
CN110694000A (en) Chinese herbal medicine preparation for treating rheumatoid arthritis
CN104208385A (en) Chinese medicinal drug for treating phlegm-dampness stagnation syndrome type tinnitus cerebri
CN102274465A (en) Traditional Chinese medicine for treating acnes
CN102552570B (en) Medicine for treating acra necrosis after bone trauma
CN102114203A (en) Traditional Chinese medicine composition for treating acnes
CN106511489A (en) Drug for treatment of rheumatism and preparation method thereof
CN106236900A (en) A kind of for compound medicine treating burn and preparation method thereof
CN104971210A (en) External lotion for treating tinea pedis and preparation method thereof
CN105770115A (en) Traditional Chinese medicine ointment for treating eczema
CN104840696A (en) Traditional Chinese medicine combination for treating qi and blood deficiency type burn
CN104984298A (en) Traditional Chinese medicine preparation having weight-losing toxin-expelling efficacies

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant