CN104547787A - Traditional Chinese medicine preparation for treating psoriasis and preparation method of traditional Chinese medicine preparation - Google Patents
Traditional Chinese medicine preparation for treating psoriasis and preparation method of traditional Chinese medicine preparation Download PDFInfo
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- CN104547787A CN104547787A CN201410854222.XA CN201410854222A CN104547787A CN 104547787 A CN104547787 A CN 104547787A CN 201410854222 A CN201410854222 A CN 201410854222A CN 104547787 A CN104547787 A CN 104547787A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
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- A61K33/36—Arsenic; Compounds thereof
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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Abstract
The invention relates to a traditional Chinese medicine preparation for treating psoriasis and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation comprises the following active ingredients in parts by weight: 30-60 parts of rhizoma smilacis glabrae, 20-40 parts of saffron crocus, 30-60 parts of herba cistanches, 10-20 parts of periostracum cicada, 20-40 parts of nodus nelumbinis rhizomatis, 30-60 parts of realgar, 10-20 parts of radix paeoniae rubra and 10-20 parts of palembus dermestoides. The preparation method comprises the steps of mixing and grinding the active ingredients in the above parts into powder of above 100 meshes, mixing the powder and pharmaceutical purified water with equal weight, uniformly stirring to prepare a blank, putting the blank in an environment at 20-25 DEG C, volatilizing water in the blank naturally to prepare a half-dry blank, and finally preparing into a corresponding dosage form. The traditional Chinese medicine preparation adopts high quality materials, is reasonable in compatibility, scientific to prepare, significant in curative effect, convenient and quick to take, safe and reliable, and stable in quality, meets requirements of traditional Chinese medicine preparation modernization and is suitable for industrial mass production.
Description
Technical field
The present invention relates to one and treat psoriasic Chinese medicine preparation and preparation method thereof, belong to technical field of Chinese medicines.
Background technology
At present, psoriasis is a kind of common cutaneous diseases, is also a kind ofly to be difficult to cure and the pertinacious disease of easily recurrence.The torment of psoriasis disease not only brings huge misery to patient, also have impact on patient and lives normally and social communication, and the psychological burden that patient can be caused heavy, if can not thoroughly cure or often recur, patient more can be made mentally and physically exhausted.
Psoriasis treatment measure was mainly contained: endo-medicine, coated medicament, embrocate liquid medicine, medicine baking the affected part after applying some drugs, acupuncture and other physical therapy methods etc. in the past.But because its emphasis is be conceived to sterilization toxic removing, cleaning diseased region mostly, and consider not enough to its root, therefore treatment actual effect not ideal enough.
The present inventor, according to Traditional Chinese medical theory, in conjunction with modern biotechnology science and technology, conducts in-depth analysis to psoriasis.Psoriasis is because heat in blood (comprising damp and hot, deficiency-heat) is subject to caused by ailment said due to cold or exposure or poison of drug again from the Chinese point of view; From modern biotechnology science and technology angle, psoriasis causes because hemocyte and Skin Cell etc., in gene aspect, pathological changes occurs, the present inventor is through exploration for many years and experiment, on the basis of Chinese Traditional Medicine, according to the theory of new " Effective Component of Chinese Medicine compatibility ", with traditional Chinese medical science strengthening the body resistance, regulate medullary cell immunologic function, depressed liver-energy dispersing and QI regulating, function of spleen and stomach regulating, outer sick treatment by oral administration of medicines is this, takes into account modern medicine cytothesis renewal theory, has been developed into one and has treated psoriasic pure oral preparation of Chinese traditional medicinal.
Summary of the invention
Technical problem to be solved by this invention is to provide one and treats psoriasic Chinese medicine preparation and preparation method thereof.
The technical scheme that the present invention solves the problems of the technologies described above is as follows:
One treats psoriasic Chinese medicine preparation, is made up of the crude drug of following parts by weight: Rhizoma Smilacis Glabrae 30 ~ 60 parts, Stigma Croci 20 ~ 40 parts, Herba Cistanches 30 ~ 60 parts, Periostracum Cicadae 10 ~ 20 parts, Nodus Nelumbinis Rhizomatis 20 ~ 40 parts, Realgar 30 ~ 60 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Martianus dermestoides Chevr. 10 ~ 20 parts.
On the basis of technique scheme, the present invention can also do following improvement:
Further, be made up of the crude drug of following parts by weight:
Rhizoma Smilacis Glabrae 40 parts, Stigma Croci 20 parts, Herba Cistanches 30 parts, Periostracum Cicadae 10 parts, Nodus Nelumbinis Rhizomatis 20 parts, Realgar 40 parts, Radix Paeoniae Rubra 10 parts, Martianus dermestoides Chevr. 10 parts.
Further, described Chinese medicine preparation can be made into the one in capsule, tablet, granule, pill, powder, sublimed preparation, slow releasing preparation or controlled release preparation.
The invention has the beneficial effects as follows:
1, Chinese medicine preparation of the present invention can strengthening the body resistance, immunity moderation function, nourishing blood to suppress the hyperactive liver, function of spleen and stomach regulating, outer sick treatment by oral administration of medicines, overcome the psoriasic many drawbacks of western medical treatment for many years, change the heat-clearing and toxic substances removing that the traditional Chinese medical science is usual, clearing away heat and cooling blood, the routine treatment of dispeling the wind of detoxifying, work out treatment psoriasis not aviod certain food, do not smear the pure oral preparation of Chinese traditional medicinal of medicine, and not impairing the liver, kidney, have no side effect.
2, Chinese medicine preparation high quality materials of the present invention, compatibility rationally, preparation science, evident in efficacy, take convenient, safe and reliable, steady quality, and meet the modern requirement of Chinese medicine preparation, be also suitable for industrialization large-scale production.
The invention provides a kind of preparation method for the treatment of psoriasic Chinese medicine preparation, comprise the steps:
(1) take Rhizoma Smilacis Glabrae 30 ~ 60 parts, Stigma Croci 20 ~ 40 parts, Herba Cistanches 30 ~ 60 parts, Periostracum Cicadae 10 ~ 20 parts, Nodus Nelumbinis Rhizomatis 20 ~ 40 parts, Realgar 30 ~ 60 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Martianus dermestoides Chevr. 10 ~ 20 parts, above-mentioned medical material is ground to form the powder of more than 100 orders;
(2) medicinal powder after described step (1) being ground is poured in agitator, the special pure water of pharmacy of weight such as to add, stirs, make stock;
(3) stock described step (2) made leaves standstill a period of time under 20-25 DEG C of environment, the part moisture content in medicine embryo is volatilized naturally, makes half-dried medicine embryo, make corresponding dosage form by the conventional fabrication process of required dosage form.
On the basis of technique scheme, the present invention can also do following improvement.
Further, described in step (1), medical material grinds to form 100 ~ 120 object powder.
Further, described in step (3), time of repose is 24 hours.
Detailed description of the invention
Be described principle of the present invention and feature below, example, only for explaining the present invention, is not intended to limit scope of the present invention.
Embodiment 1:
Take Rhizoma Smilacis Glabrae 40g, Stigma Croci 20g, Herba Cistanches 30g, Periostracum Cicadae 10g, Nodus Nelumbinis Rhizomatis 20g, Realgar 40g, Radix Paeoniae Rubra 10g, Martianus dermestoides Chevr. 10g, above-mentioned 8 taste medical materials are ground into 100 object powder altogether by grinder, in above-mentioned powder, the special pure water 180g of pharmacy of weight such as to add, stir, leave standstill at 25 DEG C and within 24 hours, make half-dried medicine embryo, half-dried medicine embryo is put into forming machine and makes pill, dry and can take after inspection;
Be more than a dosage schedule, medical material weight adds up to 180g, instructions of taking: every day 3 times, each 2g, and monthly (30 days) are a course for the treatment of; General patient is 3-4 the course for the treatment of, weighs 5-6 the course for the treatment of of patient.
Embodiment 2:
Take Rhizoma Smilacis Glabrae 30g, Stigma Croci 30g, Herba Cistanches 50g, Periostracum Cicadae 20g, Nodus Nelumbinis Rhizomatis 30g, Realgar 30g, Radix Paeoniae Rubra 20g, Martianus dermestoides Chevr. 20g, above-mentioned 8 taste medical materials are ground into 120 object powder altogether by grinder, in above-mentioned powder, the special pure water 230g of pharmacy of weight such as to add, stir, leave standstill at 20 DEG C and within 24 hours, make half-dried medicine embryo, half-dried medicine embryo is put into forming machine and makes tablet, dry and can take after inspection;
Be more than a dosage schedule, medical material weight adds up to 230g, instructions of taking: every day 3 times, each 2.6g, and monthly (30 days) are a course for the treatment of; General patient is 3-4 the course for the treatment of, weighs 5-6 the course for the treatment of of patient.
Embodiment 3:
Take Rhizoma Smilacis Glabrae 60g, Stigma Croci 40g, Herba Cistanches 60g, Periostracum Cicadae 10g, Nodus Nelumbinis Rhizomatis 40g, Realgar 60g, Radix Paeoniae Rubra 10g, Martianus dermestoides Chevr. 10g, above-mentioned 8 taste medical materials are ground into 140 object powder altogether by grinder, in above-mentioned powder, the special pure water 290g of pharmacy of weight such as to add, stir, leave standstill at 20 DEG C and within 24 hours, make half-dried medicine embryo, half-dried medicine embryo is put into forming machine and makes granule, dry and can take after inspection;
Be more than a dosage schedule, medical material weight adds up to 290g, instructions of taking: every day 3 times, each 3.2g, and monthly (30 days) are a course for the treatment of; General patient is 3-4 the course for the treatment of, weighs 5-6 the course for the treatment of of patient.
Model case:
Case 1:
Li Yihai, man, 39 years old, suffer from psoriasis existing more than 6 years, upper body chest and back 40%, leg local, takes the psoriasic Chinese medicine preparation for the treatment of of the present invention, after three courses for the treatment of (90 days), local is alleviated, skin exfoliation, is inside shown in flesh pink, after five courses for the treatment of (150 days), the basic cancellation in affected part, does not recur for nearly 2 years.
Case 2:
Liu Baoyu: man, 30 years old, left hand joint was suffered from psoriasis and is had half a year, and take the psoriasic Chinese medicine preparation for the treatment of of the present invention, after a course for the treatment of (30 days), affected part cancellation, now fully recovers, within nearly 2 years, does not recur.
Case 3:
Wang Ming: man, 25 years old, psoriasis is suffered from existing more than 2 years by face volume place, after taking Chinese medicine preparation of the present invention course for the treatment of (30 days), affected part feature is eased, after three courses for the treatment of (90 days), the basic cancellation of affected part feature of patient, suggestion continues to take 1 ~ 2 course for the treatment of of this medicine with consolidate curative effect, now fully recovers, within nearly 3 years, does not recur.
Case 4:
Zhang Wei: female, 22 years old, both legs suffered from psoriasis existing more than 2 years, and after taking Chinese medicine preparation of the present invention two courses for the treatment of (60 days), basic cancellation, suggestion continues to take 1 ~ 2 course for the treatment of of this medicine with consolidate curative effect, now fully recovers, does not nearly recur 2 years more.
Case 5:
Wang Zhong: man, 40 years old, waist suffers from psoriasis existing more than 10 years, after taking Chinese medicine preparation of the present invention five courses for the treatment of (150 days), affected part exfoliation, basic cancellation, the visible white macula of its naked eyes, suggestion continues to take 1 ~ 2 course for the treatment of of this medicine with consolidate curative effect, now fully recovers, within nearly 2 years, does not recur.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (6)
1. the psoriasic Chinese medicine preparation for the treatment of, it is characterized in that, be made up of the crude drug of following parts by weight: Rhizoma Smilacis Glabrae 30 ~ 60 parts, Stigma Croci 20 ~ 40 parts, Herba Cistanches 30 ~ 60 parts, Periostracum Cicadae 10 ~ 20 parts, Nodus Nelumbinis Rhizomatis 20 ~ 40 parts, Realgar 30 ~ 60 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Martianus dermestoides Chevr. 10 ~ 20 parts.
2. one according to claim 1 treats psoriasic Chinese medicine preparation, it is characterized in that, be made up of the crude drug of following parts by weight: Rhizoma Smilacis Glabrae 40 parts, Stigma Croci 20 parts, Herba Cistanches 30 parts, Periostracum Cicadae 10 parts, Nodus Nelumbinis Rhizomatis 20 parts, Realgar 40 parts, Radix Paeoniae Rubra 10 parts, Martianus dermestoides Chevr. 10 parts.
3. one according to claim 1 and 2 treats psoriasic Chinese medicine preparation, it is characterized in that, described Chinese medicine preparation can be made into the one in capsule, tablet, granule, pill, powder, sublimed preparation, slow releasing preparation or controlled release preparation.
4. a kind of preparation method for the treatment of psoriasic Chinese medicine preparation according to claim 1 and 2, is characterized in that, comprise the following steps:
(1) Rhizoma Smilacis Glabrae 30 ~ 60 parts, Stigma Croci 20 ~ 40 parts, Herba Cistanches 30 ~ 60 parts, Periostracum Cicadae 10 ~ 20 parts, Nodus Nelumbinis Rhizomatis 20 ~ 40 parts, Realgar 30 ~ 60 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Martianus dermestoides Chevr. 10 ~ 20 parts is taken, the powder grinding to form more than 100 orders after above-mentioned medical material mixing;
(2) by the medicinal powder of gained in step (1), pour in agitator, add the special pure water of pharmacy with the weight such as medicinal powder, stir, make stock;
(3) leave standstill a period of time under the stock that step (2) is made being placed in 20-25 DEG C of environment, the portion of water in medicine embryo is volatilized naturally, makes half-dried medicine embryo, finally make corresponding dosage form by the conventional fabrication process of required dosage form.
5. a kind of preparation method for the treatment of psoriasic Chinese medicine preparation according to claim 4, is characterized in that, described step (1) Chinese crude drug grinds to form 100 ~ 120 object powder.
6. a kind of preparation method for the treatment of psoriasic Chinese medicine preparation according to claim 4 or 5, is characterized in that, in described step (3), the time of repose of stock is 24 hours.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410854222.XA CN104547787B (en) | 2014-12-31 | 2014-12-31 | One kind treats psoriasic Chinese medicine preparation and preparation method thereof |
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| CN201410854222.XA CN104547787B (en) | 2014-12-31 | 2014-12-31 | One kind treats psoriasic Chinese medicine preparation and preparation method thereof |
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| CN104547787A true CN104547787A (en) | 2015-04-29 |
| CN104547787B CN104547787B (en) | 2018-04-03 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104984132A (en) * | 2015-07-22 | 2015-10-21 | 袁玥 | Traditional Chinese medicine for treating psoriasis caused by dampness |
| EP3363450A4 (en) * | 2015-10-15 | 2019-04-10 | Guangdong Provincial Hospital Of Chinese Medicine | Traditional chinese medicine composition for treating psoriasis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1273120A (en) * | 1999-05-11 | 2000-11-15 | 安国良 | Medical capsule for treating tinea |
| CN101757380A (en) * | 2008-10-14 | 2010-06-30 | 赵赐安 | Compound powder for oral taking for treating psoriasis |
-
2014
- 2014-12-31 CN CN201410854222.XA patent/CN104547787B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1273120A (en) * | 1999-05-11 | 2000-11-15 | 安国良 | Medical capsule for treating tinea |
| CN101757380A (en) * | 2008-10-14 | 2010-06-30 | 赵赐安 | Compound powder for oral taking for treating psoriasis |
Non-Patent Citations (3)
| Title |
|---|
| 国家药典委员会: "《中华人民共和国药典》", 30 June 2015 * |
| 戴卫波等: "中药雄黄药用历史沿革及其安全性探讨", 《时珍国医国药》 * |
| 白彦萍: "银屑病的中医辨证施治", 《中国全科医学》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104984132A (en) * | 2015-07-22 | 2015-10-21 | 袁玥 | Traditional Chinese medicine for treating psoriasis caused by dampness |
| EP3363450A4 (en) * | 2015-10-15 | 2019-04-10 | Guangdong Provincial Hospital Of Chinese Medicine | Traditional chinese medicine composition for treating psoriasis |
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| CN104547787B (en) | 2018-04-03 |
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Effective date of registration: 20151201 Address after: 264006, No. 1, Longevity Hill Road, Yantai Development Zone, Shandong, 2 Applicant after: Shandong Jiate Medical Technology Co Ltd Address before: 264000 No. 32, Yantai Development Zone, Shandong, Zhujianglu Road Applicant before: Lin Zhiguang |
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