CN101810831B - Medicament for treating gynecological diseases - Google Patents

Medicament for treating gynecological diseases Download PDF

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Publication number
CN101810831B
CN101810831B CN2010101713243A CN201010171324A CN101810831B CN 101810831 B CN101810831 B CN 101810831B CN 2010101713243 A CN2010101713243 A CN 2010101713243A CN 201010171324 A CN201010171324 A CN 201010171324A CN 101810831 B CN101810831 B CN 101810831B
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medicine
herba
caulis
medicament
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CN101810831A (en
Inventor
林艳芳
段立纲
赵应红
岩罕单
廖瑞玲
玉腊波
谭志刚
潘玉秀
刀红英
曾君
王孝蓉
肖丽香
刀会仙
陈亚梅
刘志强
邓群
刘扬扬
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XISHUANGBANNA INSTITUTE OF NATIONAL MEDICINE
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XISHUANGBANNA INSTITUTE OF NATIONAL MEDICINE
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Abstract

The invention relates to a medicament for treating gynecological diseases, which is prepared from the following raw material medicaments in part by weight: 5 parts of arundina graminifolia, 3.6 parts of Mongla dregea volubilis, 3.3 parts of motherwort herb, 3.5 parts of floralwhite clerodendrum bungei root, 2.7 parts of turmeric, 2.7 parts of mappianthus iodoies, 1 part of rhizoma corydalis and 1 part of yerbadetajo herba ecliptae. The medicament is developed by screening, researching, adding and subtracting Dai medicine traditional toxicides and formulas for clearing heat and detoxicating and activating blood and regulating menstruation on the basis of treatment principle of Dai medicine detoxication theory in Chinese traditional medicine. The medicament is prepared into modern formulations such as powder, capsules, tablets and granules and the like by combing the modern pharmaceutical technology on the basis of the raw decoction, and has the traditional characteristics of Dai medicine and the characteristics of modern preparations.

Description

A kind of medicine of treating gynaecopathia
Technical field
The present invention provides a kind of medicine and preparation technology thereof who treats gynaecopathia.
Background technology
Menoxenia, dysmenorrhea, amenorrhea, distending pain of the breast or puerperal abdonimal pain, lochia, waist abdomen pain, anemia, face furuncle furuncle, black abnormal pigmentary deposit on the skin are women's common gynecological disease, frequently-occurring disease.
Up to the present, it is available to find to have the method and the medicine of significant curative effect as yet.
Summary of the invention
The objective of the invention is to propose that a kind of drug effect is high, cost is low, the course of treatment medicine of short, easy to use treatment gynaecopathia, to solve the deficiency of prior art.
The medicine of this treatment gynaecopathia provided by the invention is to be processed by the following raw medicaments in portion by weight material: 5 parts of Herba Murdanniae Divergentis, 3.6 parts of MENGLADAJIEYAO, 3.3 parts of Herba Leonuris; 3.5 parts of Radix et Caulis Clerodendri Fragrantis roots, 2.7 parts in Rhizoma Curcumae Longae, 2.7 parts of Caulis Mappianthi Iodoidis; 1 part of Rhizoma Corydalis, 1 part of Herba Ecliptae.
Herba Murdanniae Divergentis, MENGLADAJIEYAO, Caulis Mappianthi Iodoidis are cool in nature in the prescription, and mildly bitter flavor has heat-clearing and toxic substances removing, regulate QI and blood, and the merit of the centering of calming the nerves is principal agent; Radix et Caulis Clerodendri Fragrantis root, Herba Leonuri, Herba Ecliptae have tonifying blood and regulating menstruation, the power of promoting blood circulation and stopping pain, and Rhizoma Curcumae Longae, Rhizoma Corydalis bury, wind, water tower, having that ventilation is invigorated blood circulation, the merit of reducing swelling and alleviating pain, help principal agent to strengthen the power of promoting blood circulation and stopping pain, are adjuvant.Our major-minor matching, amount to except that wind detoxifcation, tonifying blood and regulating menstruation, the purpose of promoting blood circulation and stopping pain.
On the basis of above-mentioned prescription one, also can add Flos Carthami Radix clerodendri bungei, Radix polygalae arillatae, be prescription two, this 2 flavor medical instrument has benefiting vital QI and blood; The merit of promoting blood flow to regulate menstruation can strengthen the function of prescription menstruation regulating blood nourishing medicinal, and it is thin and weak to be longer than women's body that the treatment insufficiency of vital energy and blood causes; Deficiency of vital energy insufficiency of blood, diseases such as menoxenia
On the basis of prescription one, two, also can add Radix lasianthi chinensis, Caulis et folium clerodendri bungei root,, have benefiting vital QI and blood for prescription three, promoting blood flow to regulate menstruation, the function of blood-activating analgetic, it is obstructed to be longer than the treatment QI and blood, stops and the menoxenia that causes diseases such as dysmenorrhea, amenorrhea in the blood stasis.
The present invention is based on the theoretical Therapeutic Principle of the doctor of Dai Nationality detoxifcation in the Chinese medicine; Cure traditional antidote and heat-clearing and toxic substances removing from the Dai Nationality; Screening study plus-minus development in the promoting blood flow to regulate menstruation prescription; In conjunction with the modern pharmaceutical technology on former decoction basis, developed modern formulations such as powder, capsule, tablet and granule, make it both have a Dai Nationality medicine traditional characteristics, modern preparation characteristic is arranged again.
This medical instrument has tonifying blood and regulating menstruation, the function of promoting blood circulation and stopping pain.According to the requirement of national drug administrative law hospital preparation registration, accomplished corresponding research work, prove through clinical observation on the therapeutic effect and anxious malicious experimental study; Do not find toxicity; Curative effect is safe and reliable, and is evident in efficacy, has the good development prospect and the market competitiveness.Respectively diseases such as menoxenia, dysmenorrhea, amenorrhea have been carried out observation of curative effect, wherein: menoxenia 159 examples, produce effects 68 examples, effective 76 examples, invalid 15 examples, total effective rate is 90.5%; Dysmenorrhea 141 examples, produce effects 95 examples, effective 35 examples, invalid 11 examples, total effective rate is 92.9%; Amenorrhea 97 examples, produce effects 51 examples, effective 20 examples, invalid 14 examples, total effective rate is 85.5%.
The specific embodiment
Embodiment 1, a kind of medicine of treating gynaecopathia, process by the medical material of following weight parts:
5 parts of Herba Murdanniae Divergentis, 3.6 parts of MENGLADAJIEYAO, 3.3 parts of Herba Leonuris, 3.5 parts of Radix et Caulis Clerodendri Fragrantis roots, 2.7 parts in Rhizoma Curcumae Longae, 2.7 parts of Caulis Mappianthi Iodoidis, 1 part of Rhizoma Corydalis, 1 part of Herba Ecliptae.
Adopt the modern pharmaceutical technology to process various dosage forms by above-mentioned prescription, step of preparation process is following:
1), get Herba Murdanniae Divergentis, Herba Leonuri, Radix et Caulis Clerodendri Fragrantis root, Caulis Mappianthi Iodoidis and Herba Ecliptae, add decocting in water and carry three times, 2 hours for the first time, 1.5 hours for the second time; 1 hour for the third time, merge filtrating three times, filter; Filtrating is concentrated into relative density 1.3~1.35, gets extractum, and is subsequent use;
2) get the fine powder that surplus medicine MENGLADAJIEYAO, Rhizoma Curcumae Longae and Rhizoma Corydalis pulverize separately became 100 mesh sieves, again, mixing is subsequent use;
3), with 1) step gained extractum and 2) step gained fine powder mixing; In 60 ℃ ± 5 ℃ temperature after the drying; Pulverized 100 mesh sieves, with capsule, tablet, pill, powder or the granule processed with corresponding pharmaceutic adjuvant after 70%~90% alcohol granulation, the sterilization.
Embodiment 2, a kind of medicine of treating gynaecopathia, process by the medical material of following weight parts:
Herba Murdanniae Divergentis 4.2, MENGLADAJIEYAO 4.4, Herba Leonuri 3.1, Radix et Caulis Clerodendri Fragrantis root 3.6, Flos Carthami Radix clerodendri bungei 3.7, Rhizoma Curcumae Longae 2.5, Caulis Mappianthi Iodoidis 3.3, Rhizoma Corydalis 1.5, Herba Ecliptae 3.9, Radix polygalae arillatae 3.7.
Adopt the modern pharmaceutical technology to process various dosage forms by above-mentioned prescription, step of preparation process is following:
1), get Herba Murdanniae Divergentis, Herba Leonuri, Radix et Caulis Clerodendri Fragrantis root, Flos Carthami Radix clerodendri bungei, Caulis Mappianthi Iodoidis, Herba Ecliptae and Radix polygalae arillatae, add decocting in water and carry three times, 2 hours for the first time; 1.5 hours for the second time, 1 hour for the third time, merge filtrating three times; Filter; Filtrating is concentrated into relative density 1.3~1.35, gets extractum, and is subsequent use;
2) get the fine powder that surplus medicine MENGLADAJIEYAO, Rhizoma Curcumae Longae and Rhizoma Corydalis pulverize separately became 100 mesh sieves, again, mixing is subsequent use;
3), with 1) step gained extractum and 2) step gained fine powder mixing; In 60 ℃ ± 5 ℃ temperature after the drying; Pulverized 100 mesh sieves, with capsule, tablet, pill, powder or the granule processed with corresponding pharmaceutic adjuvant after 70%~90% alcohol granulation, the sterilization.
Embodiment 3, a kind of medicine of treating gynaecopathia, process by the medical material of following weight parts:
Herba Murdanniae Divergentis 4.1, MENGLADAJIEYAO 3, Herba Leonuri 2.9, Radix et Caulis Clerodendri Fragrantis root 2.5, Rhizoma Curcumae Longae 1.8, Caulis Mappianthi Iodoidis 2.2, Rhizoma Corydalis 1, Herba Ecliptae 3.3, Radix polygalae arillatae 2.9, Flos Carthami Radix clerodendri bungei 3.2, Radix lasianthi chinensis 3.5, Caulis et folium clerodendri bungei root 3.4.
Adopt the modern pharmaceutical technology to process various dosage forms by above-mentioned prescription, step of preparation process is following:
1), get Herba Murdanniae Divergentis, Herba Leonuri, Radix et Caulis Clerodendri Fragrantis root, Caulis Mappianthi Iodoidis, Herba Ecliptae, Radix polygalae arillatae, Flos Carthami Radix clerodendri bungei, Radix lasianthi chinensis and Caulis et folium clerodendri bungei root, add decocting in water and carry three times, 2 hours for the first time; 1.5 hours for the second time, 1 hour for the third time, merge filtrating three times; Filter; Filtrating is concentrated into relative density 1.3~1.35, gets extractum, and is subsequent use;
2) get surplus medicine MENGLADAJIEYAO, Rhizoma Curcumae Longae and Rhizoma Corydalis, again, pulverize separately became the fine powder of 100 mesh sieves, and mixing is subsequent use;
3) with 1) step gained extractum and 2) step gained fine powder mixing, in 60 ℃ ± 5 ℃ temperature, after the drying, pulverized 100 mesh sieves, process capsule, tablet, pill, powder or granule with 70%~90% alcohol granulation, sterilization back with corresponding pharmaceutic adjuvant.

Claims (2)

1. medicine of treating gynaecopathia is characterized in that being processed by the medical material of following weight parts:
5 parts of Herba Murdanniae Divergentis, 3.6 parts of MENGLADAJIEYAO, 3.3 parts of Herba Leonuris, 3.5 parts of Radix et Caulis Clerodendri Fragrantis roots, 2.7 parts in Rhizoma Curcumae Longae, 2.7 parts of Caulis Mappianthi Iodoidis, 1 part of Rhizoma Corydalis, 1 part of Herba Ecliptae.
2. a kind of preparation technology who treats the medicine of gynaecopathia according to claim 1 is characterized in that step is following:
1), get Herba Murdanniae Divergentis, Herba Leonuri, Radix et Caulis Clerodendri Fragrantis root, Caulis Mappianthi Iodoidis and Herba Ecliptae, add decocting in water and carry three times, 2 hours for the first time, 1.5 hours for the second time; 1 hour for the third time, merge filtrating three times, filter; Filtrating is concentrated into relative density 1.3 ~ 1.35, gets extractum, and is subsequent use;
2) get the fine powder that surplus medicine MENGLADAJIEYAO, Rhizoma Curcumae Longae and Rhizoma Corydalis pulverize separately became 100 mesh sieves, again, mixing is subsequent use;
3), with 1) step gained extractum and 2) step gained fine powder mixing, in 60 ℃ ± 5 ℃ temperature, after the drying, pulverized 100 mesh sieves, process capsule, tablet or granule with 70%~90% alcohol granulation, sterilization back with corresponding pharmaceutic adjuvant.
CN2010101713243A 2010-05-13 2010-05-13 Medicament for treating gynecological diseases Active CN101810831B (en)

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102552485B (en) * 2012-03-07 2013-11-20 贵州宏宇药业有限公司 Health-care product for postpartum recovery and preparation method thereof
CN104958737A (en) * 2015-07-29 2015-10-07 华菊 Medicine for treating irregular menstruation and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1557412A (en) * 2004-01-19 2004-12-29 蒙永业 Chinese medicine composite preparation for treating blood syndrome of woman
CN101288729A (en) * 2008-06-06 2008-10-22 中国人民解放军第四军医大学 Chinese medicine granule for treating various dysmenorrhea

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1557412A (en) * 2004-01-19 2004-12-29 蒙永业 Chinese medicine composite preparation for treating blood syndrome of woman
CN101288729A (en) * 2008-06-06 2008-10-22 中国人民解放军第四军医大学 Chinese medicine granule for treating various dysmenorrhea

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
吕显荣等.傣医"雅解"理论及其方药的研究进展.《云南中医学院学报》.2009,第32卷(第2期),
玉腊波.傣药"雅解"(解药)临床应用举隅.《中国民族医药杂志》.2008,(第7期),
玉腊波.傣药"雅解"(解药)临床应用举隅.《中国民族医药杂志》.2008,(第7期), *

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