CN102178763B - Medicament for treating anaphylactoid purpura - Google Patents
Medicament for treating anaphylactoid purpura Download PDFInfo
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- CN102178763B CN102178763B CN201110119466A CN201110119466A CN102178763B CN 102178763 B CN102178763 B CN 102178763B CN 201110119466 A CN201110119466 A CN 201110119466A CN 201110119466 A CN201110119466 A CN 201110119466A CN 102178763 B CN102178763 B CN 102178763B
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Abstract
The invention relates to a medicament for treating anaphylactoid purpura, which is characterized by being prepared from the following raw materials in part by weight: 5 to 10 parts of weeping forsythia, 10 to 30 parts of fineleaf schizonepeta herb, 10 to 30 parts of Sinkiang arnebia root, 10 to 30 parts of red paeony root, 5 to 10 parts of garden burnet root, 5 to 15 parts of liquoric root, 10 to 30 parts of hairyvein agrimonia herb and 5 to 20 parts of safflower. The invention has the advantage that the medicament is prepared from common Chinese herbal medicines on the basis of the conventional theory of traditional Chinese medicine, and has the effects of clearing heat and detoxicating, dispelling wind and relieving exterior syndrome and cooling blood and promoting blood circulation; and in a formula, weeping forsythia is used for clearing heat and detoxicating, fineleaf schizonepeta herb is used for dispelling wind and relieving exterior syndrome, Sinkiang arnebia root is used for clearing heat and cooling blood, garden burnet root is used for cooling blood and stopping bleeding, hairyvein agrimonia herb is used for astringing to arrest bleeding, safflower is used for promoting blood circulation and dispelling stasis, red paeony root is used for stopping bleeding and dispelling stasis, and liquoric root is used for harmonizing the medicaments. The medicament has the good effects of purpura caused by injury of blood collaterals by heat, obstruction of collaterals by blood stasis, exogenous wind-heat evil and internal invading into blood vessels, can reduce the recurrence rate effectively and does not have toxic or side effect.
Description
Technical field:
The present invention relates to a kind of medicine of treating anaphylactoid purpura, belong to field of traditional Chinese.
Background technology:
Anaphylactoid purpura is a kind of blood capillary and arteriolar a kind of allergic angiitis of invading skin or other organs, and at present, the medicine that is used to treat anaphylactoid purpura is few; Western medical treatment adopts immunosuppressant only; Medicine disease controlling such as hormone, long-term a large amount of this type medicines that use are prone to cause untoward reaction more, are prone to recurrence; Shortcomings such as drug withdrawal difficulty, and the Chinese medicine or the combination of Chinese and Western medicine have curative effect preferably to this type treatment of diseases.
Summary of the invention:
The objective of the invention is to: a kind of medicine of new treatment anaphylactoid purpura is provided, satisfies the needs of medical treatment better.
Its technical scheme is: a kind of medicine of treating anaphylactoid purpura is made up of following components in weight percentage: Fructus Forsythiae 5-10 part, Herba Schizonepetae charcoal 10-30 part, Radix Arnebiae (Radix Lithospermi) 10-30 part, Radix Paeoniae Rubra 10-30 part, Radix Sanguisorbae 5-10 part, Radix Glycyrrhizae 5-15 part, Herba Agrimoniae 10-30 part, Flos Carthami 5-20 part.
Advantage of the present invention is: it is to instruct according to traditional Chinese medicine theory, adopts common several kinds of Chinese crude drug prescriptions to form.The effect of tool heat-clearing and toxic substances removing, expelling pathogenic wind from the body surface, removing heat from blood and promoting blood circulation, Fructus Forsythiae heat-clearing and toxic substances removing in the side, Herba Schizonepetae expelling pathogenic wind from the body surface, Radix Arnebiae (Radix Lithospermi) clearing away heat and cooling blood; The Radix Sanguisorbae cooling blood for hemostasis, Herba Agrimoniae astringing to arrest bleeding, Flos Carthami blood circulation promoting and blood stasis dispelling, Radix Paeoniae Rubra hemostasis blood stasis dispelling; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, for injury of blood collaterals by heat, obstruction of collaterals by blood stasis, the evil diseases caused by exogenous pathogenic factor of wind heat; In scurry that the purpura symptom has curative effect preferably due to the blood network, and effectively reduce relapse rate, have no side effect.
The specific embodiment:
Embodiment 1: get 10 parts of Fructus Forsythiaes, 11 parts of Herba Schizonepetae charcoals, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 30 parts of Radix Paeoniae Rubra, 8 parts of Radix Sanguisorbaes, 9 parts in Radix Glycyrrhizae, 15 parts of Herba Agrimoniaes, 10 parts on Flos Carthami, decocte with water twice was measured 1.5 hours for 10 times for the first time; Measured 1.0 hours for 8 times for the second time, decocting liquid filters, and filtrating merges; Concentrate, drying is after dry thing is pulverized; Through adding dextrin and Icing Sugar, process granule, packing promptly gets.Boiled water is taken after mixing it with water during use.
Embodiment 2: get 10 parts of Fructus Forsythiaes, 30 parts of Herba Schizonepetae charcoals, 10 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Paeoniae Rubra, 5 parts of Radix Sanguisorbaes, 15 parts in Radix Glycyrrhizae, 10 parts of Herba Agrimoniaes, 5 parts on Flos Carthami, decocte with water twice was measured 1.5 hours for 10 times for the first time; Measured 1.0 hours for 8 times for the second time, decocting liquid filters, and filtrating merges; Concentrate, drying is after dry thing is pulverized; Add the water mix homogeneously, agitation procedure is processed the watered pill, and boiled water takes.
Embodiment 3; Get 5 parts of Fructus Forsythiaes, 10 parts of Herba Schizonepetae charcoals, 30 parts of Radix Arnebiae (Radix Lithospermi)s, 10 parts of Radix Paeoniae Rubra, 10 parts of Radix Sanguisorbaes, 5 parts in Radix Glycyrrhizae, 10 parts of Herba Agrimoniaes, 15 parts on Flos Carthami, decocte with water twice was measured 1.5 hours for 10 times for the first time; Measured 1.0 hours for 8 times for the second time, decocting liquid filters, and filtrating merges; Concentrate, drying is after dry thing is pulverized; Add the refined honey mix homogeneously, process honeyed pill, boiled water takes.
Embodiment 4: get 8 parts of Fructus Forsythiaes, 20 parts of Herba Schizonepetae charcoals, 10 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of Radix Paeoniae Rubra, 7 parts of Radix Sanguisorbaes, 10 parts in Radix Glycyrrhizae, 20 parts of Herba Agrimoniaes, 20 parts on Flos Carthami, decocte with water twice was measured 1.5 hours for 10 times for the first time; Measured 1.0 hours for 8 times for the second time, decocting liquid filters, and filtrating merges; Concentrate; Drying, dry thing is distributed into powder after pulverizing.Boiled water is taken after mixing it with water during use.
Embodiment 5: get 6 parts of Fructus Forsythiaes, 25 parts of Herba Schizonepetae charcoals, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 25 parts of Radix Paeoniae Rubra, 6 parts of Radix Sanguisorbaes, 9 parts in Radix Glycyrrhizae, 30 parts of Herba Agrimoniaes, 9 parts on Flos Carthami, decocte with water twice was measured 1.5 hours for 10 times for the first time, measured 1.0 hours for 8 times for the second time; Decocting liquid filters, and filtrating merges, and concentrates; Drying, dry thing adds starch after pulverizing; Granulate, be pressed into tablet, boiled water takes.
Above-mentioned five embodiment of the present invention all are that reconcentration was processed other dosage form after medicine was processed water decoction by proportioning.With regard to water decoction, after taking for two weeks, effectively improve symptoms such as the early stage skin purpura of patients with anaphylactoid purpura, mucosal bleeding, this medicine to the effective percentage of anaphylactoid purpura more than 95%.Other dosage form is the enriched product of water decoction, and its effective ingredient is identical with water decoction, so curative effect is also identical, the clinical effectiveness of this medicine is described with water decoction below.
Clinical data:
1, case load: 20 examples
2, diagnostic criteria: clinical manifestation
(1) there are low grade fever, pharyngalgia, malaise or upper respiratory tract infection in premorbid 1-3 week.
(2) occur the skin purpura repeatedly, can accompany stomachache, have blood in stool (abdomen type), arthralgia (joint type) and hematuria, edema (kidney type).
(3) platelet count, function and blood coagulation inspection are normal.
(4) get rid of vasculitis and purpura due to other reason.
3, observe the case standard:
3.1 include the case standard in: meet above-mentioned diagnostic criteria;
3.2 get rid of the case standard;
A had used Drug therapy person;
The B age is person more than 70 years old;
C merges the heart, brain, liver, kidney, disorder of hematopoietic system or insane;
D do not meet the standard of including in, not by the regulation medication, can't make a decision curative effect person.
4, observation index
1. observe treatment back clinical symptoms and improve situation.Comprise subcutaneous mucosa hemorrhage, have blood in stool, a series of bleeding regression times such as hematuria, stomachache, arthralgia remission time, the time that nephritis patient urine protein, occult blood disappear, observed and recorded is 1 time weekly; Have urine examined weekly conventional 2 times; First quarter moon is looked into renal function and routine blood test 1 time.2. observe untoward reaction.
5, curative effect decision standard
5.1 all transference cures of produce effects treatment back, relevant inspection is normal.Observe 1 year not the recidivist can be considered clinical recovery.With the treatment or other treatment compare, reach the recovery from illness required time significantly shorten, complication rate and in 1 year relapse rate significantly minimizing person can be considered the treatment produce effects.
5.2 effectively the treatment back state of an illness is clearly better, and is clinical improvement but do not recover normal visible, compares with not treatment group to reach this degree required time and obviously shorten, and can be considered effective.If treatment recovery from illness but recidivist again in two months can be considered in the recent period effectively.
5.3 invalid: degree and required time that treatment back characteristic of disease takes a turn for the better, compare no marked difference with not treatment group.
6, method: take water decoction, be a course of treatment at twice, 7 day every day, took for 4 courses of treatment altogether.
7, result: 7 people that fully recover, produce effects 13 people, effective 9 people, invalid 1 people, total effective rate reaches 96%.The treatment group is with prolonging the course of treatment, and curative effect increases, and in 1 week of medication, the skin purpura obviously reduces, and in 2 weeks of medication, the most skin purpura disappears, and after 4 courses of treatment of medication, effectively reduces relapse rate.
Claims (2)
1. medicine of treating anaphylactoid purpura, it is characterized in that: it is to process with following materials of weight proportions: Fructus Forsythiae 5-10 part, Herba Schizonepetae charcoal 10-30 part, Radix Arnebiae (Radix Lithospermi) 10-30 part, Radix Paeoniae Rubra 10-30 part, Radix Sanguisorbae 5-10 part, Radix Glycyrrhizae 5-15 part, Herba Agrimoniae 10-30 part, Flos Carthami 5-20 part.
2. treatment allergy purpura according to claim 1 is characterized in that: the dosage form of medicine is water decoction, granule, the watered pill, powder, honeyed pill or tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110119466A CN102178763B (en) | 2011-05-04 | 2011-05-04 | Medicament for treating anaphylactoid purpura |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110119466A CN102178763B (en) | 2011-05-04 | 2011-05-04 | Medicament for treating anaphylactoid purpura |
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| Publication Number | Publication Date |
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| CN102178763A CN102178763A (en) | 2011-09-14 |
| CN102178763B true CN102178763B (en) | 2012-10-17 |
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| CN201110119466A Expired - Fee Related CN102178763B (en) | 2011-05-04 | 2011-05-04 | Medicament for treating anaphylactoid purpura |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104667019B (en) * | 2015-03-23 | 2018-07-10 | 佛山手心制药有限公司 | It is a kind of treat diseases caused by external factors caused by purpura disease Chinese medicine composition |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1385213A (en) * | 2002-06-14 | 2002-12-18 | 赵金凯 | Decolouring technology for compound Chinese herbal medicine |
| CN101077386A (en) * | 2007-05-25 | 2007-11-28 | 赵善菊 | Traditional Chinese medicine composition for treating allergic purpura |
| CN101396531A (en) * | 2008-10-09 | 2009-04-01 | 刘运波 | Traditional Chinese medicine for treating allergic purpura |
-
2011
- 2011-05-04 CN CN201110119466A patent/CN102178763B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1385213A (en) * | 2002-06-14 | 2002-12-18 | 赵金凯 | Decolouring technology for compound Chinese herbal medicine |
| CN101077386A (en) * | 2007-05-25 | 2007-11-28 | 赵善菊 | Traditional Chinese medicine composition for treating allergic purpura |
| CN101396531A (en) * | 2008-10-09 | 2009-04-01 | 刘运波 | Traditional Chinese medicine for treating allergic purpura |
Non-Patent Citations (6)
| Title |
|---|
| 李福玲等.过敏性紫癜的中医药治疗概况.《中医药信息》.2006,第23卷(第2期),18-20. |
| 王见宾等.过敏性紫癜中医证治规律初探.《中国中医急症》.2004,第13卷(第5期), |
| 过敏性紫癜中医证治规律初探;王见宾等;《中国中医急症》;20040530;第13卷(第5期);301-302 * |
| 过敏性紫癜的中医药治疗概况;李福玲等;《中医药信息》;20060228;第23卷(第2期);18-20 * |
| 过敏性紫癜辨治十法;郜燕霞等;《中外医疗》;20091130(第11期);126-127 * |
| 郜燕霞等.过敏性紫癜辨治十法.《中外医疗》.2009,(第11期),126-127. |
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