CN102198228A - Chinese medicinal preparation for treating hypertension - Google Patents

Chinese medicinal preparation for treating hypertension Download PDF

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Publication number
CN102198228A
CN102198228A CN2011101194316A CN201110119431A CN102198228A CN 102198228 A CN102198228 A CN 102198228A CN 2011101194316 A CN2011101194316 A CN 2011101194316A CN 201110119431 A CN201110119431 A CN 201110119431A CN 102198228 A CN102198228 A CN 102198228A
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parts
radix
root
blood
effect
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CN2011101194316A
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Chinese (zh)
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李平
赵洛沙
惠鹏鹏
张全红
惠振明
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Abstract

The invention relates to a Chinese medicinal preparation for treating hypertension, which comprises the following Chinese herbal medicines in part by weight: 20 to 40 parts of motherwort herb, 20 to 40 parts of root of red-rooted salvia, 20 to 40 parts of common selfheal fruit-spike, 10 to 20 parts of chrysanthemum, 15 to 30 parts of white paeony root, 10 to 30 parts of cassia seed, 10 to 30 parts of gambir plant, 10 to 30 parts of stir-fried spiny jujube kernel, 10 to 30 parts of figwort root, 10 to 30 parts of Szechuan lovage rhizome, 5 to 15 parts of tall gastrodia tuber, 6 to 20 parts of baical skullcap root, 6 to 20 parts of earthworm, 2 to 8 parts of twotooth achyranthes root and 6 to 15 parts of orange peel. The Chinese medicinal preparation has the effects of clearing heat and cooling blood, promoting blood circulation and dispelling blood stasis, dispelling wind and heat, calming liver and improving eyesight, detoxicating and relieving exterior syndrome, has a good curative effect on the hypertension caused by various reasons, and has the advantages of quick response, obvious treatment effect, good tolerance, low cost and no toxic or side effect.

Description

Treat hypertensive Chinese medicine preparation
Technical field
The present invention relates to the hypertensive Chinese medicine preparation of a kind of treatment.Have clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, dispelling wind and heat pathogens, suppressing the hyperactive liver makes eye bright, the effect of heat-clearing and toxic substances removing, expelling pathogenic wind from the body surface, and the hypertension that causes at a variety of causes all has good efficacy.
Background technology
The traditional Chinese medical science thinks that the reason of hypertension incidence mainly is the deficiency of both the liver and kidney that impairment of the kidney due to indulgence in sexual activities, depressed rage impairing the liver cause.Cause gas not carry blood and cause make human body wane and wax of yin and yang imbalance, particularly Liver and kidney imbalance of YIN and YANG, and can produce congestion because of the stagnation of QI.The traditional Chinese medical science is emphasis conditioning hepatic and renal function in the hypertensive process of treatment, allows it reach harmonious, normal operation, and the mediation by meridians can make the QI and blood abundance, improves in internal environment, the balanced body negative and positive and effects a radical cure hypertension.It is various to treat hypertensive Chinese medicine preparation, and its therapeutic purposes emphasize particularly on different fields, and curative effect differs greatly.
Summary of the invention
The object of the present invention is to provide a kind of have clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, dispelling wind and heat pathogens, suppressing the hyperactive liver makes eye bright, the Chinese medicine preparation of the effect of heat-clearing and toxic substances removing, expelling pathogenic wind from the body surface, and the hypertension that causes at a variety of causes all has good efficacy.
The raw material medical material that the present invention chooses is respectively that Herba Leonuri, Radix Salviae Miltiorrhizae, Spica Prunellae, Flos Chrysanthemi, the Radix Paeoniae Alba, Semen Cassiae, Ramulus Uncariae Cum Uncis, Semen Ziziphi Spinosae (parched), Radix Scrophulariae, Rhizoma Chuanxiong, Rhizoma Gastrodiae, Radix Scutellariae, Pheretima, Radix Achyranthis Bidentatae, Pericarpium Citri tangerinae make up, these drug regimens are made various efficacy of drugs synergism, thereby can realize clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, dispelling wind and heat pathogens, suppressing the hyperactive liver makes eye bright, the purpose of the effect of heat-clearing and toxic substances removing, expelling pathogenic wind from the body surface.Because Herba Leonuri: [property of medicine] is hot, bitter, is slightly cold.GUIXIN, liver, urinary bladder channel.[effect] blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema, heat-clearing and toxic substances removing.[pharmacological action] this product has significant excited uterus effect, and frequency of uterine contraction, amplitude and tensity are increased.And have and increase coronary flow, decreased heart rate, microcirculation improvement, antiplatelet aggregation, antithrombotic and form, strengthen cellular immune function, blood pressure lowering, diuresis and suppress effects such as fungus.
Radix Salviae Miltiorrhizae: [property of medicine] hardship is slightly cold.GUIXIN, pericardium, Liver Channel.[effect] blood circulation promoting and blood stasis dispelling, the removing heat from blood eliminating carbuncle, relieving restlessness clears away heart-fire.[pharmacological action] this product can coronary artery dilator, blood flow increasing, resist myocardial ischemia, microcirculation improvement, reduction myocardial oxygen consumption, improve cardiac function, strengthen myocardial contraction, blood pressure lowering, blood fat reducing, anticoagulation, antithrombotic, protect the liver, antiallergic, adjusting immunologic function, antiinflammatory, calmness, antibiotic etc.
Spica Prunellae: [property of medicine] is bitter, hot, and is cold.Return liver, gallbladder meridian.[effect] clearing away liver-fire, Disperse hepatic depression, blood pressure lowering.
Flos Chrysanthemi: [property of medicine] is hot, sweet, bitter, is slightly cold.Return liver, lung meridian.[effect] dispelling wind and heat pathogens, suppressing the hyperactive liver makes eye bright, heat-clearing and toxic substances removing.
The Radix Paeoniae Alba: [property of medicine] is bitter, sour, is slightly cold.Return liver, spleen channel.[effect] yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, suppressing liver-YANG.[pharmacological action] this product has effects such as regulating immunity function, calmness, analgesia, spasmolytic, anticoagulant, coronary artery dilator, blood pressure lowering, antiinflammatory and protects the liver.
Semen Cassiae: [property of medicine] is sweet, bitter, is slightly cold, returns liver, kidney, large intestine channel.[effect] liver heat removing and eyesight improving, loosening bowel to relieve constipation.
Ramulus Uncariae Cum Uncis: [property of medicine] is sweet, is slightly cold.Return liver, pericardium channel.[effect] endogenous wind stopping relieving convulsion, the heat clearing away suppressing the hyperactive liver.[pharmacological action] this product has effects such as the spasm, anticoagulant of calmness, blood pressure lowering, releasing bronchus, intestinal and uterine smooth muscle.
Semen Ziziphi Spinosae (parched): [property of medicine] is bitter, sour, and is flat.GUIXIN, Liver Channel.[effect] tranquilizing by nourishing the heart, arresting sweating.[pharmacological action] this product has calmness, hypnosis, convulsion, analgesia, arrhythmia, improves effects such as myocardial ischemia, blood pressure lowering, blood fat reducing, promotion lymphocyte transformation, antiplatelet aggregation.
Radix Scrophulariae: [property of medicine] is bitter, sweet, is slightly cold.GUIXIN, liver, kidney channel.[effect] clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.
Rhizoma Chuanxiong: [property of medicine] suffering, temperature.Return liver, gallbladder, pericardium channel.[effect] blood-activating and qi-promoting, wind-expelling pain-stopping.[pharmacological action] Rhizoma Chuanxiong can suppress vascular smooth muscle contraction, coronary artery dilator, coronary blood flow increasing, reduction peripheral vascular resistance, microcirculation improvement, anticoagulant, antithrombotic formation, and has effects such as calmness, spasmolytic, adjusting immunity function, anti-radiation and antitumor.
Rhizoma Gastrodiae: [property of medicine] is sweet, and is flat.Return Liver Channel.[effect] endogenous wind stopping relieving convulsion, suppressing liver-YANG, wind-damp dispelling, stopping numbness pain.[pharmacological action] this product has calmness, convulsion, blood pressure lowering, resists myocardial ischemia, arrhythmia, anticoagulant, analgesia, antiinflammatory, enhancing learning and memory in rats, strengthen effects such as cell and humoral immunity function.
Radix Scutellariae: [property of medicine] hardship, cold.Return lung, gallbladder, stomach, large intestine channel.[effect] heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.Effects such as that [pharmacological action] this product has is analgesic, calm, antiinflammatory, antibiotic, antiviral, antiallergic, promotion cellular immunization, blood fat reducing, hepatoprotective, sharp liver, diuresis, blood pressure lowering, anticoagulation, antithrombotic formation, antioxidation and antitumor.
Pheretima: [property of medicine] is salty, and is cold.Return liver, spleen, urinary bladder channel.[effect] clearing heat for calming endogenous wind is relievingd asthma, collateral dredging, diuresis.[pharmacological action] this product have calmness, convulsion, analgesic, relieving asthma, effect such as blood pressure lowering, prolongation platelet thrombus and fibrinous thrombus formation time.
Radix Achyranthis Bidentatae: [property of medicine] is bitter, sour, and is flat.Return liver, kidney channel.[effect] promoting blood circulation to restore menstrual flow, inducing diuresis for treating stranguria syndrome, it is descending to draw blood (fire), invigorating the liver and kidney, bone and muscle strengthening.
Pericarpium Citri tangerinae: [property of medicine] is hot, bitter, temperature.Return spleen, lung meridian.[effect] regulates the flow of vital energy, and in the accent, dampness is reduced phlegm.[pharmacological action] this product have suppress the intestines and stomach smooth muscle, promote gastric secretion, anti-gastric-ulcer, protect the liver, function of gallbladder promoting, eliminate the phlegm, relieving asthma, effects such as antiinflammatory, antibiotic, antiviral, rising blood pressure.
The consumption of drug component of the present invention is groped to sum up to draw through the inventor in a large number, and each amounts of components all has more satisfactory effect at following weight range: Herba Leonuri 20-40 part, Radix Salviae Miltiorrhizae 20-40 part, Spica Prunellae 20-40 part, Flos Chrysanthemi 10-20 part, Radix Paeoniae Alba 15-30 part, Semen Cassiae 10-30 part, Ramulus Uncariae Cum Uncis 10-30 part, Semen Ziziphi Spinosae (parched) 10-30 part, Radix Scrophulariae 10-30 part, Rhizoma Chuanxiong 10-30 part, Rhizoma Gastrodiae 5-15 part, Radix Scutellariae 6-20 part, Pheretima 6-20 part, Radix Achyranthis Bidentatae 2-8 part, Pericarpium Citri tangerinae 6-15 part.
Be preferably: Herba Leonuri, Radix Salviae Miltiorrhizae, each 30 parts of Spica Prunellaes, 15 parts of Flos Chrysanthemis, 20 parts of the Radix Paeoniae Albas, 15 parts of Semen Cassiaes, 20 parts of Ramulus Uncariae Cum Uncis, 15 parts of Semen Ziziphi Spinosae (parched)s, 15 parts of Radix Scrophulariaes, 15 parts of Rhizoma Chuanxiongs, 9 parts in Rhizoma Gastrodiae, 10 parts of Radix Scutellariaes, 10 parts of Pheretimas, 6 parts of Radix Achyranthis Bidentataes, 9 parts of Pericarpium Citri tangerinaes.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.For example these crude drug pulverize mix homogeneously powder can be taken after mixing it with water; Can be with these crude drug decocting together, concentrate decocting liquid then and take, perhaps concentrated decocting liquid is condensed into cream and is processed into pill and takes; Bring into play drug effect better for each raw material that makes this medicine, carry out special extraction at certain crude drug, as ethanol extraction, these can not be used to limit protection scope of the present invention.Active component of the present invention can add various conventional adjuvant required when preparing different dosage form, be prepared into any peroral dosage form commonly used as disintegrating agent, lubricant, binding agent etc. with the method for Chinese medicinal of routine, as pill, powder, tablet, capsule, oral liquid etc.
Selected medical material is played clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, dispelling wind and heat pathogens altogether, and suppressing the hyperactive liver makes eye bright, the effect of heat-clearing and toxic substances removing, expelling pathogenic wind from the body surface.Improved human body immune function by for oral administration, the hypertension that causes at a variety of causes has good efficacy.
Effect of the present invention and curative effect are verified by clinical practice, the basic document of clinical practice: 2005--2011, and outpatient service is accepted for medical treatment and is suitable for crowd's 356 examples; Wherein 226 examples have coronary heart disease, hyperlipidemia, hypertension history; 130 examples have heart disease, diabetic history.The described preparation of Application Example (capsule), every clothes 3 grams, every day sooner or later each once, Instant Drinks 7--21 day continuously.Outpatient service is accepted for medical treatment and is suitable in crowd's 356 examples, and 323 routine blood pressures transfer to normally, all the other remissions, and do not have uncomfortable reaction.Conclusion is: the present invention have effect rapidly, therapeutic effect obviously, better tolerance, beneficial effect with low cost, without any side effects.
The specific embodiment
The hypertensive Chinese medicine preparation of a kind of treatment of the present invention, crude drug and the composition by weight thereof chosen are respectively: Herba Leonuri 20-40 part, Radix Salviae Miltiorrhizae 20-40 part, Spica Prunellae 20-40 part, Flos Chrysanthemi 10-20 part, Radix Paeoniae Alba 15-30 part, Semen Cassiae 10-30 part, Ramulus Uncariae Cum Uncis 10-30 part, Semen Ziziphi Spinosae (parched) 10-30 part, Radix Scrophulariae 10-30 part, Rhizoma Chuanxiong 10-30 part, Rhizoma Gastrodiae 5-15 part, Radix Scutellariae 6-20 part, Pheretima 6-20 part, Radix Achyranthis Bidentatae 2-8 part, Pericarpium Citri tangerinae 6-15 part.
Embodiment one: choose crude drug and composition by weight is respectively: 30 parts of Herba Leonuris, 30 parts of Radix Salviae Miltiorrhizaes, 30 parts of Spica Prunellaes, 15 parts of Flos Chrysanthemis, 20 parts of the Radix Paeoniae Albas, 15 parts of Semen Cassiaes, 20 parts of Ramulus Uncariae Cum Uncis, 15 parts of Semen Ziziphi Spinosae (parched)s, 15 parts of Radix Scrophulariaes, 15 parts of Rhizoma Chuanxiongs, 9 parts in Rhizoma Gastrodiae, 10 parts of Radix Scutellariaes, 10 parts of Pheretimas, 6 parts of Radix Achyranthis Bidentataes, 9 parts of Pericarpium Citri tangerinaes.Method of Chinese medicinal with routine is prepared into pill, powder, tablet.
Embodiment two, the crude drug of choosing and composition by weight thereof are respectively: Herba Leonuri, Radix Salviae Miltiorrhizae, each 25 parts of Spica Prunellaes, 10 parts of Flos Chrysanthemis, 20 parts of the Radix Paeoniae Albas, 15 parts of Semen Cassiaes, 10 parts of Ramulus Uncariae Cum Uncis, 10 parts of Semen Ziziphi Spinosae (parched)s, 15 parts of Radix Scrophulariaes, 15 parts of Rhizoma Chuanxiongs, 9 parts in Rhizoma Gastrodiae, 10 parts of Radix Scutellariaes, 10 parts of Pheretimas, 6 parts of Radix Achyranthis Bidentataes, 9 parts of Pericarpium Citri tangerinaes.Method of Chinese medicinal with routine is prepared into tablet, capsule, oral liquid.

Claims (1)

1. treat hypertensive Chinese medicine preparation for one kind, it is characterized in that crude drug and the composition by weight thereof chosen are respectively: Herba Leonuri 20-40 part, Radix Salviae Miltiorrhizae 20-40 part, Spica Prunellae 20-40 part, Flos Chrysanthemi 10-20 part, Radix Paeoniae Alba 15-30 part, Semen Cassiae 10-30 part, Ramulus Uncariae Cum Uncis 10-30 part, Semen Ziziphi Spinosae (parched) 10-30 part, Radix Scrophulariae 10-30 part, Rhizoma Chuanxiong 10-30 part, Rhizoma Gastrodiae 5-15 part, Radix Scutellariae 6-20 part, Pheretima 6-20 part, Radix Achyranthis Bidentatae 2-8 part, Pericarpium Citri tangerinae 6-15 part.
CN2011101194316A 2011-05-10 2011-05-10 Chinese medicinal preparation for treating hypertension Pending CN102198228A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526470A (en) * 2012-02-16 2012-07-04 许从玉 Medicinal composition for treating primary hypertension
CN103071037A (en) * 2013-01-28 2013-05-01 威海东宝制药有限公司 Traditional Chinese medicine for treating hypertension
CN103330816A (en) * 2013-04-08 2013-10-02 杨家骥 Chinese proprietary medicine used for treating hypertension and manufacture method thereof
CN104013849A (en) * 2014-06-23 2014-09-03 张伯华 Traditional Chinese medicinal composition for treating hypertension and preparation method thereof
CN104087463A (en) * 2014-07-08 2014-10-08 句容市丁庄老方葡萄专业合作社 Health grape wine for preventing hypertension and preparation process thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526470A (en) * 2012-02-16 2012-07-04 许从玉 Medicinal composition for treating primary hypertension
CN102526470B (en) * 2012-02-16 2013-05-29 崔合芳 Medicinal composition for treating primary hypertension
CN103071037A (en) * 2013-01-28 2013-05-01 威海东宝制药有限公司 Traditional Chinese medicine for treating hypertension
CN103330816A (en) * 2013-04-08 2013-10-02 杨家骥 Chinese proprietary medicine used for treating hypertension and manufacture method thereof
CN103330816B (en) * 2013-04-08 2015-06-03 杨家骥 Chinese proprietary medicine used for treating hypertension and manufacture method thereof
CN104013849A (en) * 2014-06-23 2014-09-03 张伯华 Traditional Chinese medicinal composition for treating hypertension and preparation method thereof
CN104087463A (en) * 2014-07-08 2014-10-08 句容市丁庄老方葡萄专业合作社 Health grape wine for preventing hypertension and preparation process thereof

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Application publication date: 20110928