CN105250427A - Pharmaceutical composition for treating heart diseases - Google Patents
Pharmaceutical composition for treating heart diseases Download PDFInfo
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- CN105250427A CN105250427A CN201510749067.XA CN201510749067A CN105250427A CN 105250427 A CN105250427 A CN 105250427A CN 201510749067 A CN201510749067 A CN 201510749067A CN 105250427 A CN105250427 A CN 105250427A
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- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 21
- 208000019622 heart disease Diseases 0.000 title claims abstract description 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 24
- 241000237636 Pheretima Species 0.000 claims description 21
- 241000628997 Flos Species 0.000 claims description 20
- 239000009636 Huang Qi Substances 0.000 claims description 20
- 238000002360 preparation method Methods 0.000 claims description 20
- 210000000582 semen Anatomy 0.000 claims description 20
- 238000002156 mixing Methods 0.000 claims description 18
- 239000008187 granular material Substances 0.000 claims description 15
- 239000000843 powder Substances 0.000 claims description 13
- 239000000706 filtrate Substances 0.000 claims description 12
- 238000005325 percolation Methods 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 239000003814 drug Substances 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 7
- 239000004375 Dextrin Substances 0.000 claims description 6
- 229920001353 Dextrin Polymers 0.000 claims description 6
- 206010013786 Dry skin Diseases 0.000 claims description 6
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 6
- 229930006000 Sucrose Natural products 0.000 claims description 6
- 230000006837 decompression Effects 0.000 claims description 6
- 235000019425 dextrin Nutrition 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 6
- 239000000284 extract Substances 0.000 claims description 6
- 239000012467 final product Substances 0.000 claims description 6
- 239000012530 fluid Substances 0.000 claims description 6
- 238000004064 recycling Methods 0.000 claims description 6
- 239000002904 solvent Substances 0.000 claims description 6
- 229960004793 sucrose Drugs 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 4
- 238000009472 formulation Methods 0.000 claims description 4
- 238000007598 dipping method Methods 0.000 claims description 2
- 239000002552 dosage form Substances 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 239000006187 pill Substances 0.000 claims description 2
- 239000008280 blood Substances 0.000 abstract description 10
- 210000004369 blood Anatomy 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 7
- 230000003213 activating effect Effects 0.000 abstract description 3
- 244000144730 Amygdalus persica Species 0.000 abstract 1
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 241001061264 Astragalus Species 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 235000006040 Prunus persica var persica Nutrition 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 241001233061 earthworms Species 0.000 abstract 1
- 238000005728 strengthening Methods 0.000 abstract 1
- 210000004233 talus Anatomy 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 description 8
- 230000017531 blood circulation Effects 0.000 description 7
- 238000005516 engineering process Methods 0.000 description 6
- 230000001737 promoting effect Effects 0.000 description 5
- 235000009508 confectionery Nutrition 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 239000012567 medical material Substances 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 241000208340 Araliaceae Species 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000002330 Congenital Heart Defects Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 208000009525 Myocarditis Diseases 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010049418 Sudden Cardiac Death Diseases 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000002180 anti-stress Effects 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 208000028831 congenital heart disease Diseases 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 208000015210 hypertensive heart disease Diseases 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 208000004124 rheumatic heart disease Diseases 0.000 description 1
- 208000014221 sudden cardiac arrest Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
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Abstract
The invention provides a pharmaceutical composition for treating heart diseases. The pharmaceutical composition is characterized by comprising the following components in parts by weight according to a prescription: 20-60 parts of astragalus, 10-30 parts of angelica sinensis, 10-30 parts of red paeony roots, 10-30 parts of ligusticum wallichii, 5-20 parts of peach kernels, 5-20 parts of safflowers and 1-15 parts of earthworms. The pharmaceutical composition provided by the invention has the effects of invigorating qi, activating blood and strengthening the heart and is simple in components, scientific and reasonable in formula and remarkable heart disease treatment effect.
Description
Technical field
The invention belongs to field of traditional Chinese, be specifically related to a kind of pharmaceutical composition for the treatment of heart disease.
Background technology
Heart disease is the general name of heart disease, comprises the various heart diseases such as rheumatic heart disease, congenital heart disease, hypertensive heart disease, coronary heart disease, myocarditis.The number one killer of the mankind is sudden cardiac arrest (being called for short SCA).At present according to the numeral that World Health Organization (WHO) issues, the whole world, often in dead 3 people, just has 1 people to die from cardiovascular disease, China, has hundreds of thousands people to die from heart disease every year.Heart disease has very large puzzlement and threat to patient, although have in some now, western medicine mode, curative effect is all comparatively general, can not effectively alleviate heart disease preferably and treat.Therefore, develop a kind ofly to have no side effect, scientific formulation, taking convenience, treatment heart disease evident in efficacy medicine be desirable.
Summary of the invention
The Chinese medicine composition for the treatment of heart disease that the present invention aims to provide a kind of stable curative effect, has no side effect.
For achieving the above object, a kind of pharmaceutical composition for the treatment of heart disease of the present invention, its specific embodiments is:
A kind of pharmaceutical composition for the treatment of heart disease of the present invention, is characterized in that this pharmaceutical composition prescription number is counted: Radix Astragali 20-60 part, each 10-30 part of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, each 5-20 part of Semen Persicae, Flos Carthami, Pheretima 1-15 part.
Further, a kind of pharmaceutical composition for the treatment of heart disease of the present invention, is characterized in that this pharmaceutical composition prescription number is counted: Radix Astragali 30-50 part, each 12-24 part of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, each 8-15 part of Semen Persicae, Flos Carthami, Pheretima 5-10 part.
Further, a kind of pharmaceutical composition for the treatment of heart disease of the present invention, is characterized in that this pharmaceutical composition prescription number is counted: the Radix Astragali 45 parts, each 16 parts of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, each 10 parts of Semen Persicae, Flos Carthami, Pheretima 8 parts.
Pharmaceutical composition described in any one of the present invention, is characterized in that, described preparation is oral formulations.
Further, preparation of the present invention, is characterized in that, described preparation is made up of Chinese medicine composition and pharmaceutically acceptable carrier, and dosage form comprises water decoction, pill, capsule, granule, electuary and oral liquid.
Further, preparation of the present invention, is characterized in that, described preparation is tablet.
Further, preparation of the present invention, is characterized in that, the preparation method of this tablet is: 1) by the recipe quantity Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Semen Persicae, Flos Carthami, Pheretima wears into coarse powder, and mixing, according to the percolation under fluid extract and extractum item, with 4-8 times amount 60% ethanol as solvent, dipping 12-18 hour, slowly percolation, collect 6 times amount and to filter liquid, decompression recycling ethanol is also concentrated into the clear paste that relative density is 1.06 ~ 1.08, leaves standstill 24 hours;
2) medicinal residues add 8 times amount soak by water 1 hour, and filter, filtrate reduced in volume to relative density is the clear paste of 1.06 ~ 1.08, leave standstill 24 hours, merge above-mentioned two kinds of clear paste, mixing, boil 30 minutes, filter while hot, filtrate reduced in volume to relative density is the clear paste of 1.30 ~ 1.32, add cane sugar powder and dextrin, granulate, 80 DEG C of dryings, let cool, mixing, granulate, tabletting, to obtain final product.
The each component pharmacology analysis of prescription of the present invention:
The Radix Astragali: sweet, tepor.Return lung, spleen, liver, kidney channel.Have enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Radix Angelicae Sinensis: sweet, pungent, warm, returns liver, the heart, spleen channel.Enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.
Radix Paeoniae Rubra: bitter, is slightly cold.Return Liver Channel.There is clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling.
Rhizoma Chuanxiong: pungent, temperature.Enter liver, gallbladder meridian.Activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.
Semen Persicae: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.
Flos Carthami: pungent, warm, GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, stimulates the menstrual flow.
Pheretima: salty, cold.Return liver, spleen, urinary bladder channel.Pheretima effect: clearing away heat and relieving the wind syndrome, relievings asthma, dredging collateral, diuresis.
Asthenia of qi and blood then should be mended, and heart blood stasis then should disappear.The pure benefit then stasis of blood is not gone, and purely disappears then just more empty, therefore controls and should mend double the executing that disappear.Reuse Radix Astragali QI invigorating in side, be equipped with Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Semen Persicae, Flos Carthami with blood circulation promoting and blood stasis dispelling; Pheretima expel wind to dredge collateral; Add Radix Aconiti Lateralis Preparata during postscript, Radix Ginseng provides guarantee for obtaining good therapeutic effect.All medicines share, and play the merit of benefiting QI for activating blood circulation heart tonifying altogether.
Beneficial effect of the present invention is:
1. prescription scientific formulation, evident in efficacy.
2. prescription crude drug source is wide, and technique is simple, is applicable to large-scale production, has industrialization prospect.
Detailed description of the invention
The present invention is further illustrated below for embodiment.
Embodiment 1
Prescription:
The Radix Astragali 45 parts, each 16 parts of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, each 10 parts of Semen Persicae, Flos Carthami, Pheretima 8 parts.
Preparation technology:
1) by the recipe quantity Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Semen Persicae, Flos Carthami, Pheretima wears into coarse powder, mixing, according to the percolation under fluid extract and extractum item, with 6 times amount 60% ethanol as solvent, flood 15 hours, slowly percolation, collect 6 times amount to filter liquid, decompression recycling ethanol is also concentrated into the clear paste that relative density is 1.06 ~ 1.08, leaves standstill 24 hours;
2) medicinal residues add 8 times amount soak by water 1 hour, and filter, filtrate reduced in volume to relative density is the clear paste of 1.06 ~ 1.08, leave standstill 24 hours, merge above-mentioned two kinds of clear paste, mixing, boil 30 minutes, filter while hot, filtrate reduced in volume to relative density is the clear paste of 1.30 ~ 1.32, add cane sugar powder and dextrin, granulate, 80 DEG C of dryings, let cool, mixing, granulate, tabletting, to obtain final product.
Embodiment 2
Prescription:
The Radix Astragali 45 parts, each 16 parts of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, each 10 parts of Semen Persicae, Flos Carthami, Pheretima 8 parts.
Preparation technology:
1) by the recipe quantity Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Semen Persicae, Flos Carthami, Pheretima wears into coarse powder, mixing, according to the percolation under fluid extract and extractum item, with 8 times amount 60% ethanol as solvent, flood 18 hours, slowly percolation, collect 6 times amount to filter liquid, decompression recycling ethanol is also concentrated into the clear paste that relative density is 1.06 ~ 1.08, leaves standstill 24 hours;
2) medicinal residues add 8 times amount soak by water 1 hour, and filter, filtrate reduced in volume to relative density is the clear paste of 1.06 ~ 1.08, leave standstill 24 hours, merge above-mentioned two kinds of clear paste, mixing, boil 30 minutes, filter while hot, filtrate reduced in volume to relative density is the clear paste of 1.30 ~ 1.32, add cane sugar powder and dextrin, granulate, 80 DEG C of dryings, let cool, mixing, granulate, tabletting, to obtain final product.
Embodiment 3
Prescription:
The Radix Astragali 45 parts, each 16 parts of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, each 10 parts of Semen Persicae, Flos Carthami, Pheretima 8 parts.
Decoction preparation technology:
First, by the recipe quantity Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Semen Persicae, Flos Carthami, Pheretima medical material warm water is soaked 20 minutes (water yield of immersion is advisable to flood powder 2 ~ 3cm); Secondly, be placed on by medicine on fire, endure out with big fire, timing after boiling, decocts 60 minutes; Finally, first time fried medicinal liquid is poured out, add appropriate hot water (being advisable just to flood medical material) and carry out second time and decoct, about the about 30 minutes time of second time decoction.To mix with second time medicinal liquid by medicinal liquid for the first time, obtain decoction of the present invention.
Embodiment 4
Prescription:
The Radix Astragali 45 parts, each 16 parts of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, each 10 parts of Semen Persicae, Flos Carthami, Pheretima 8 parts.
Capsule preparation technology:
1) by the recipe quantity Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Semen Persicae, Flos Carthami, Pheretima wears into coarse powder, mixing, according to the percolation under fluid extract and extractum item, with 8 times amount 60% ethanol as solvent, flood 18 hours, slowly percolation, collect 6 times amount to filter liquid, decompression recycling ethanol is also concentrated into the clear paste that relative density is 1.06 ~ 1.08, leaves standstill 24 hours;
2) medicinal residues add 8 times amount soak by water 1 hour, and filter, filtrate reduced in volume to relative density is the clear paste of 1.06 ~ 1.08, leave standstill 24 hours, merge above-mentioned two kinds of clear paste, mixing, boil 30 minutes, filter while hot, filtrate reduced in volume to relative density is the clear paste of 1.30 ~ 1.32, add cane sugar powder and dextrin, granulate, 80 DEG C of dryings, let cool, mixing, granulates, filled capsules and get final product.
Embodiment 5
Prescription:
The Radix Astragali 45 parts, each 16 parts of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, each 10 parts of Semen Persicae, Flos Carthami, Pheretima 8 parts.
Preparation Technology of Granules:
1) by the recipe quantity Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Semen Persicae, Flos Carthami, Pheretima wears into coarse powder, mixing, according to the percolation under fluid extract and extractum item, with 8 times amount 60% ethanol as solvent, flood 18 hours, slowly percolation, collect 6 times amount to filter liquid, decompression recycling ethanol is also concentrated into the clear paste that relative density is 1.06 ~ 1.08, leaves standstill 24 hours;
2) medicinal residues add 8 times amount soak by water 1 hour, and filter, filtrate reduced in volume to relative density is the clear paste of 1.06 ~ 1.08, leave standstill 24 hours, merge above-mentioned two kinds of clear paste, mixing, boil 30 minutes, filter while hot, filtrate reduced in volume to relative density is the clear paste of 1.30 ~ 1.32, add cane sugar powder and dextrin, granulate, 80 DEG C of dryings, let cool, mixing, granule processed, to obtain final product.
Clinical application effect of the present invention:
One, physical data accepts patient's totally 10 examples for medical treatment, 48 years old mean age.
Two, Therapeutic Method is according to Medications Example one of the present invention, and tablet prepared by preferred preparation method, one day three times, each three, decoction being taken warmly.It within 15th, is a course for the treatment of.Three, therapeutic outcome statistics
Treat after 15 days, fully recover 7 people, effective 2 people, invalid 1 people, total effective rate 90%.Wherein: total effective rate=cure rate+effective percentage.It should be noted that; above-described embodiment is only preferred embodiment of the present invention; be not used for limiting protection scope of the present invention; protection scope of the present invention is as the criterion with claims; equivalent replacement done on the basis of technique scheme or substitute, all belongs to protection scope of the present invention.
Claims (7)
1. treat a pharmaceutical composition for heart disease, it is characterized in that this pharmaceutical composition prescription number is counted: Radix Astragali 20-60 part, each 10-30 part of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, each 5-20 part of Semen Persicae, Flos Carthami, Pheretima 1-15 part.
2. a kind of pharmaceutical composition for the treatment of heart disease according to claim 1, is characterized in that this pharmaceutical composition prescription number is counted: Radix Astragali 30-50 part, each 12-24 part of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, each 8-15 part of Semen Persicae, Flos Carthami, Pheretima 5-10 part.
3. a kind of pharmaceutical composition for the treatment of heart disease according to claim 1, is characterized in that this pharmaceutical composition prescription number is counted: the Radix Astragali 45 parts, each 16 parts of Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, each 10 parts of Semen Persicae, Flos Carthami, Pheretima 8 parts.
4. the pharmaceutical composition according to any one of claim 1-3, is characterized in that, described preparation is oral formulations.
5. preparation according to claim 4, is characterized in that, described preparation is made up of Chinese medicine composition and pharmaceutically acceptable carrier, and dosage form comprises water decoction, pill, capsule, granule, electuary and oral liquid.
6. preparation according to claim 5, is characterized in that, described preparation is tablet.
7. preparation according to claim 6, is characterized in that, the preparation method of this tablet is: 1) by the recipe quantity Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Semen Persicae, Flos Carthami, Pheretima wears into coarse powder, mixing, according to the percolation under fluid extract and extractum item, with 4-8 times amount 60% ethanol as solvent, dipping 12-18 hour, slowly percolation, collect 6 times amount to filter liquid, decompression recycling ethanol is also concentrated into the clear paste that relative density is 1.06 ~ 1.08, leaves standstill 24 hours;
2) medicinal residues add 8 times amount soak by water 1 hour, and filter, filtrate reduced in volume to relative density is the clear paste of 1.06 ~ 1.08, leave standstill 24 hours, merge above-mentioned two kinds of clear paste, mixing, boil 30 minutes, filter while hot, filtrate reduced in volume to relative density is the clear paste of 1.30 ~ 1.32, add cane sugar powder and dextrin, granulate, 80 DEG C of dryings, let cool, mixing, granulate, tabletting, to obtain final product.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107929392A (en) * | 2017-12-26 | 2018-04-20 | 广州中医药大学 | A kind of pharmaceutical composition, preparation method and application |
CN115137771A (en) * | 2022-06-14 | 2022-10-04 | 广西纯正堂制药有限公司 | Thrombus eliminating tablet for treating ischemic cardiac and cerebral vascular diseases and its prepn |
CN115463174A (en) * | 2022-09-27 | 2022-12-13 | 渭南山野士科技发展有限公司 | Pure traditional Chinese medicine preparation for tonifying qi, strengthening heart and recovering cardiac function and preparation method thereof |
Citations (1)
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CN102114085A (en) * | 2010-06-11 | 2011-07-06 | 李银春 | Traditional Chinese medicine oral decoction for treating coronary heart disease |
-
2015
- 2015-11-08 CN CN201510749067.XA patent/CN105250427A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102114085A (en) * | 2010-06-11 | 2011-07-06 | 李银春 | Traditional Chinese medicine oral decoction for treating coronary heart disease |
Non-Patent Citations (2)
Title |
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温瑞书: "《王清任医方精要》", 31 January 2003, 河北科学技术出版社 * |
高华: "《最新国家药品标准实施手册 第2卷》", 31 March 2004, 社会科学文献出版社 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107929392A (en) * | 2017-12-26 | 2018-04-20 | 广州中医药大学 | A kind of pharmaceutical composition, preparation method and application |
CN115137771A (en) * | 2022-06-14 | 2022-10-04 | 广西纯正堂制药有限公司 | Thrombus eliminating tablet for treating ischemic cardiac and cerebral vascular diseases and its prepn |
CN115137771B (en) * | 2022-06-14 | 2024-05-03 | 九华华源药业(桂林)有限公司 | Thrombolytic tablet for treating ischemic cardiovascular and cerebrovascular diseases and preparation method thereof |
CN115463174A (en) * | 2022-09-27 | 2022-12-13 | 渭南山野士科技发展有限公司 | Pure traditional Chinese medicine preparation for tonifying qi, strengthening heart and recovering cardiac function and preparation method thereof |
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Application publication date: 20160120 |
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RJ01 | Rejection of invention patent application after publication |