CN1135997C - 'Shexingkeyu' capsule for treating cardiovascular and cerebrovascular diseases and its preparing process - Google Patents
'Shexingkeyu' capsule for treating cardiovascular and cerebrovascular diseases and its preparing process Download PDFInfo
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- CN1135997C CN1135997C CNB001245287A CN00124528A CN1135997C CN 1135997 C CN1135997 C CN 1135997C CN B001245287 A CNB001245287 A CN B001245287A CN 00124528 A CN00124528 A CN 00124528A CN 1135997 C CN1135997 C CN 1135997C
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Abstract
The present invention discloses a shexing petechia removal capsule for treating cardiovascular and cerebrovascular diseases and a preparation method of the shexing petechia removal capsule. The medicines in the capsules contain pulverized red sage root, chuanxiong rhizome, crataegus, pedate pinallia jackinthepulpit rhizome, notoginseng, borneol, leech and musk in order to treat patients with apoplexy, hemiplegia, cerebral embolism, sequelae, coronary heart diseases and angina pectoris by fat reduction, pressure reduction, blood circulation promotion, blood stasis removal, etc. The effective rate achieves 95.2%, and the theory and the efficiency of the shexing capsule are increased by that decocted antelope horn, thinleaf milkwort roots, raw cassia tora uncaria, or ginseng, prepared pinellia tuber and poria from yunnan of china are matched when patients with serious illness states of cerebral thrombosis and myocardial infarction; myocardial infarction are treated.
Description
The present invention relates to a kind of Chinese medicine that contains the treatment cardiovascular and cerebrovascular disease of raw material, medicinal preparation, specifically a kind of medicine for the treatment of cardiovascular and cerebrovascular disease.
In recent years, the sickness rate of cardiovascular and cerebrovascular disease was on the rise.At present, the medicine of treatment cardiovascular and cerebrovascular disease has multiple.Have a kind of " DIAOXINXUE KANG " to be produced, laid particular emphasis on the capsule for the treatment of cardiovascular disease by Chinese Academy Of Sciences Chengdu Diao Pharmaceutical Co., Ltd, the total Saponin of extraction steroidal is refining from plant forms, and does not disclose the flavour of a drug component.Introduction says that the treatment effective percentage to coronary heart disease angor reaches 88.6%, and improving the myocardial ischemia effective percentage is 55.4%, just when taking according to quantity, the time gastrointestinal upset, regurgitation phenomenon arranged.In addition, " storax capsule for treating coronary heart disease " by the BJ Pharmaceutical Co., Ltd. is released contains Styrax, Borneolum Syntheticum, Olibanum, Radix Aristolochiae, Lignum Santali Albi etc., function is that fragrance is opened surreptitiously, promoting the circulation of QI to relieve pain, do not disclose full medicine component weight ratio, also need take FUFANG DANSHEN PIAN simultaneously, its effective percentage is 58.9%.More than two kinds of medicines not explanation heavier to the state of an illness, cerebral thrombosis, apoplexy sequela, the treatment of myocardial infarction etc. take place.
The purpose of this invention is to provide a kind of medicine and compounding agent for the treatment of cardiovascular and cerebrovascular disease, reach treatment and prevention apoplexy, hemiplegia, cerebral thrombosis, apoplexy sequela, coronary heart disease, angina pectoris disease with blood fat reducing, blood pressure lowering, blood circulation promoting and blood stasis dispelling.
Task of the present invention is achieved in that the pharmaceutical pack of treatment cardiovascular and cerebrovascular disease contains Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Fructus Crataegi, Rhizoma Arisaematis, Radix Notoginseng, Borneolum Syntheticum, Hirudo, Moschus and adds ripe grain powder (in order to strengthen the Moschus volume, handled easily), can also add the Chinese medicine decoction compounding agent that contains cooperation increase pharmacology, effect.
The drug weight degree of treatment cardiovascular and cerebrovascular disease is: Radix Salviae Miltiorrhizae 27.03%, Rhizoma Chuanxiong 27.03%, Fructus Crataegi 27.03%, Rhizoma Arisaematis 5.4%, Radix Notoginseng 5.4%, Borneolum Syntheticum 1.08%, Hirudo 6.49%, Moschus 0.27% close ripe grain powder 0.27%.
The medicine method for making of treatment cardiovascular and cerebrovascular disease:
(1) dries after choosing high-quality medical material, decontamination, dust;
(2) Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Fructus Crataegi, Rhizoma Arisaematis are added decocting respectively and endure, can endure becoming the decoction drop go out to be added with decocting, then decoction is boiled into 1/10 concentrated medicament after, be dried into medicated powder below 70 ℃ again;
(3) with Radix Notoginseng, Borneolum Syntheticum, Hirudo pulverize separately levigation, through the 120 mesh sieves medicated powder of hanking;
(4) with Moschus with mix with ripe grain weight, that do, pulverize levigation, through the 120 mesh sieves medicated powder of hanking;
(5) go out the medicated powder of respectively distinguishing the flavor of by component weight ratio weighing, it fully mixed, stir, in quantitatively incapsulating, the treatment cardiovascular and cerebrovascular disease medicament capsule.This medicament capsule have fragrance open steal, promoting flow of QI and blood, the stasis-dispelling and pain-killing performance is used for apoplexy, hemiplegia, cerebral thrombosis, apoplexy sequela, myocardial infarction disease and coronary heart disease, anginal prevention and treatment.
For " cerebral thrombosis " apoplexy, hemiplegia disease treatment, but adapted be decocted in water for oral dose and can increase the compounding agent of pharmacology, effect I, its compounding agent I drug weight percentage ratio is: Cornu Saigae Tataricae 0.43%, Radix Polygalae 13%, give birth to Semen Cassiae 64.93%, Ramulus Uncariae Cum Uncis 21.64%.
For treatment " coronary atherosclerotic heart disease; Acute posterior myocardial infarction " patient, but the adapted decoction can increase the compounding agent II of pharmacology, effect, and its compounding agent II drug weight percentage ratio is: Radix Ginseng 25%, Rhizoma Pinelliae Preparata 25%, Poria 50%.
The present invention mainly is that removing blood stasis, removing blood stasis collateral dredging, blood stasis dispelling thrombolytic have improved hemorheology and microcirculation, removes because the cerebral thrombosis that hematogenous blockage is caused in the cerebral tissue.Myocardial infarction and cerebral thrombosis belong to the stasis of blood together and fall ill in passages through which vital energy circulates.In this medicine, reuse the Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, impel blood stasis to go fresh blood to give birth to blood vessel dilating microcirculation improvement, blood flow increasing and anticoagulant and thrombolytic effect.But the Fructus Crataegi blood fat reducing is invigorated blood circulation, and it is active that Radix Notoginseng is that blood circulation promoting and blood stasis dispelling is promoted blood circulation, can anti-platelet aggregation.Strengthen Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling dynamics with Fructus Crataegi, Radix Notoginseng.Rhizoma Chuanxiong is a blood circulation promoting and blood stasis dispelling, and the invigorate blood circulation analgesic therapy, all medicines of the Hirudo removing blood stasis of invigorating blood circulation, Moschus, Borneolum Syntheticum complemented each other, and the cardiovascular and cerebrovascular disease clinical symptoms is alleviated.The present invention was secret recipe originally, selected statistics at random from beginning in 89 years, used the medicament capsule treatment of treatment cardiovascular and cerebrovascular disease, through 42 days six courses of treatment, course of disease elder was reached 3 years, 2 months patient of the shortest person, and average effectiveness level reaches 95.2%; Learn for hemorheology, medical effects such as blood fat, dysarteriotony are fine, and are safe and reliable, and erythra appears in 7/1000ths patient once in a while, dies away after the drug withdrawal.
When the medicament capsule pharmacology that increases the treatment cardiovascular and cerebrovascular disease, effect, among the used compounding agent I, Cornu Saigae Tataricae is salty-cold, suppressing the hyperactive liver to relieve the wind syndrome, and heat-clearing and toxic substances removing cooperates living Semen Cassiae, Ramulus Uncariae Cum Uncis suppressing the hyperactive liver to dispel the wind to strengthen the effect of Cornu Saigae Tataricae.Use the Radix Polygalae eleminating phlegm and freeing channels, four medicines cooperate, and liver-yang is put down dives the blood vessels smoothness.In compounding agent II, reuse ginseng qi-tonifying benefit essence, use the Poria invigorating the spleen for dissipating phlegm, the Rhizoma Pinelliae Preparata drying dampness to eliminate phlegm.Share it, is that QI invigorating, blood stasis dispelling pursue expectorant, is used for the treatment of coronary heart disease, angina pectoris.
Most preferred embodiment of the present invention: select for use the oven dry of high-quality medical material, decontamination stand-by, with Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Fructus Crataegi, Rhizoma Arisaematis stew soup medicine, concentrate, be dried into medicated powder; Radix Notoginseng, Borneolum Syntheticum, Hirudo levigation are crossed 120 mesh sieves become medicated powder, Moschus adds commensurability parched rice flour, and levigation is crossed 120 mesh sieves and become medicated powder.The above-mentioned medicated powder weighing of respectively distinguishing the flavor of is got: Radix Salviae Miltiorrhizae 27.03g, Fructus Crataegi 27.03g, Rhizoma Chuanxiong 27.03g, Rhizoma Arisaematis 5.4g, Radix Notoginseng 5.4g, Borneolum Syntheticum 1.08g, Hirudo 6.49g, Moschus 0.27g close parched rice flour 0.27g, it is fully mixed, stir, in incapsulating with 0.5g amount, promptly become the medicament capsule of treatment cardiovascular and cerebrovascular disease.
Clinical case one:
Male Lee 79 years old, is " myocardial infarction " on February 13rd, 98 at Linfen Prefecture's hospital diagnosis, coronary heart disease, cardiac insufficiency III level, 2/time of the medicament capsules of oral medication cardiovascular and cerebrovascular disease, order clothes three times serve on 42 days, checked to Linfen Prefecture hospital after having a holiday 2 months, all card shapes disappear, and recover normal, can go to work in the fields now.
Clinical case two:
Yan male 71 years old suffers from hypertension for many years, and aphasis took place suddenly in JIUYUE, 95 on the 8th, the right side limb activity is unfavorable, suddenly distortion of commissure after four days, stiff tongue is felt embarrassed to mention, right half body paralysis, doctor trained in Western medicine is diagnosed as " cerebral thrombosis ", take 3/time of the medicament capsules of treatment cardiovascular and cerebrovascular disease, day clothes secondary adds compounding agent I, day decoction potion took for two weeks, the wind of turn is flat latently positive, stops up the expectorant heat of resistance, also lies prostrate Qinghua, language is still sharp, bicker gradually just, and the right side limbs are hemiplegia, arteries and veins is stringy and rolling pulse still, be the stagnant passages through which vital energy circulates of the stasis of blood, network gas is not declared.Transform 2/time of medicament capsules taking the treatment cardiovascular and cerebrovascular disease into, days three times, cooperate massage 21 days, health check-up: refreshing clear language is still sharp, and facial paralysis is corrected, and right upper and lower muscular strength II level is not drawn pathologic reflex.Continue to take the medicament capsule twice-daily of treatment cardiovascular and cerebrovascular disease, 2/time to 42 days drug withdrawals were followed up a case by regular visits to 2 years, blood pressure stabilization, and action is multiple normal.
Clinical case three:
Ma male 48 years old, the first visit in 1, of 92 on JIUYUE, electrocardio diagram: acute posterior myocardial infarction, be radiated to right upper arm, for coronary atherosclerotic heart disease, moderate pulse are slided 2/time of the medicament capsules of oral medication cardiovascular and cerebrovascular disease, day three times, decoction compounding agent II, day potion.Logotype 7 days, after begin only to take the medicament capsule of treatment cardiovascular and cerebrovascular disease, daily secondary, one of logotype was followed up a case by regular visits to and not to be seen recurrence in 1 year.
Claims (1)
1, a kind of medicine for the treatment of cardiovascular and cerebrovascular disease, it is characterized in that: it is made up of capsule and compounding agent, and wherein capsule is made by following materials of weight proportions medicine:
Radix Salviae Miltiorrhizae 27.03% Rhizoma Chuanxiong 27.03% Fructus Crataegi 27.03%
Rhizoma Arisaematis 5.4% Radix Notoginseng 5.4% Borneolum Syntheticum 1.08%
Hirudo 6.49% Moschus 0.27% closes ripe grain powder 0.27%
Its method for making is:
(1) dries after choosing high-quality medical material, decontamination, dust;
(2) Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Fructus Crataegi, Rhizoma Arisaematis are added decocting respectively and endure, can endure becoming the decoction drop go out to be added with decocting, then decoction is boiled into 1/10 concentrated medicament after, be dried into medicated powder below 70 ℃ again;
(3) with Radix Notoginseng, Borneolum Syntheticum, Hirudo pulverize separately levigation, through the 120 mesh sieves medicated powder of hanking;
(4) with Moschus with mix with ripe grain weight, that do, pulverize levigation, through the 120 mesh sieves medicated powder of hanking;
(5) go out the medicated powder of respectively distinguishing the flavor of by component weight ratio weighing, it fully mixed, stir, in quantitatively incapsulating, medicament capsule;
This compounding agent is to be fried in shallow oil by following materials of weight proportions liquid medicine to form:
Cornu Saigae Tataricae 0.43% Radix Polygalae 13% is given birth to Semen Cassiae 64.93% Ramulus Uncariae Cum Uncis 21.64%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001245287A CN1135997C (en) | 2000-09-19 | 2000-09-19 | 'Shexingkeyu' capsule for treating cardiovascular and cerebrovascular diseases and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001245287A CN1135997C (en) | 2000-09-19 | 2000-09-19 | 'Shexingkeyu' capsule for treating cardiovascular and cerebrovascular diseases and its preparing process |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98103009A Division CN1067573C (en) | 1998-07-13 | 1998-07-13 | Shexingkeyu capsule for curing cardiovascular and cerebrovascular disease and preparing process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1293049A CN1293049A (en) | 2001-05-02 |
| CN1135997C true CN1135997C (en) | 2004-01-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB001245287A Expired - Fee Related CN1135997C (en) | 2000-09-19 | 2000-09-19 | 'Shexingkeyu' capsule for treating cardiovascular and cerebrovascular diseases and its preparing process |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101084961B (en) * | 2006-06-08 | 2011-10-05 | 天津天士力制药股份有限公司 | Medicinal composition containing ligusticum wallichii and musk, preparation method and preparation |
| KR101643580B1 (en) * | 2015-07-24 | 2016-07-29 | 금강기계공업(주) | Beam for pallet |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1313108C (en) * | 2005-09-02 | 2007-05-02 | 于勇春 | Medicine for treating cardiovascular and cerebrovascular disease |
| CN103417826B (en) * | 2013-07-08 | 2015-04-29 | 鲁奎 | Chinese medicine for treating angina and preparation method thereof |
| CN104906524B (en) * | 2015-06-30 | 2018-03-27 | 何先植 | A kind of Chinese medicine package and its instructions of taking, preparation method for being used to treat coronary heart disease |
-
2000
- 2000-09-19 CN CNB001245287A patent/CN1135997C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101084961B (en) * | 2006-06-08 | 2011-10-05 | 天津天士力制药股份有限公司 | Medicinal composition containing ligusticum wallichii and musk, preparation method and preparation |
| KR101643580B1 (en) * | 2015-07-24 | 2016-07-29 | 금강기계공업(주) | Beam for pallet |
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| Publication number | Publication date |
|---|---|
| CN1293049A (en) | 2001-05-02 |
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