CN102872443A - Drug for treating migraine and preparation method thereof - Google Patents
Drug for treating migraine and preparation method thereof Download PDFInfo
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- CN102872443A CN102872443A CN2012104166223A CN201210416622A CN102872443A CN 102872443 A CN102872443 A CN 102872443A CN 2012104166223 A CN2012104166223 A CN 2012104166223A CN 201210416622 A CN201210416622 A CN 201210416622A CN 102872443 A CN102872443 A CN 102872443A
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Abstract
The invention discloses a drug for treating migraine and a preparation method thereof. The drug for treating the migraine is mainly prepared from the following traditional Chinese medicines in a certain weight ratio: radix rehmanniae recen, gastrodia elata, earthworm, safflower carthamus, Radix Paeoniae Rubra, Ligusticum wallichii, notopterygium root, chrysanthemum, radix gentianae, lithospermum, plantain seed, radix paeoniae alba, Ledebouriella seseloides Wolff, asarum, cinnamon and the like. The drug disclosed by the invention has functions of tonifying spleen and harmonizing stomach and calming heart to soothe the nerves. The drug is fast in effect when being used for treating the migraine; the course of treatment is short; the migraine cannot relapse; and the cure rate is high.
Description
Technical field
The present invention relates to a kind of medicine for treating antimigraine and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Migraines is a kind of pulsation headache of recurrent exerbation, is belonged to " rich and influential family " in numerous headache types.It often has the tendencys such as flash of light, blurred vision, extremity numbness before breaking out, few minutes occurred the pain that side head one is jumped to 1 hour or so, and gradually aggravated, until occurring after Nausea and vomiting, sensation, which just has, to be taken a turn for the better, and headache is alleviated in quiet, dark surrounds or after sleep.Can be with nerve, mental function disorder when preceding or breaking-out occurs for headache.At present, analgestic and stabilization agent pain of alleviation are used doctor trained in Western medicine more, but the side effect of Western medicine is big.Therefore, to the Chinese medicine of effectively treatment antimigraine there is great demand in people.
The content of the invention
Research and clinical experiment and checking repeatedly of the present inventor according to theory of traditional Chinese medical science, have found the medicine of effectively treatment antimigraine, so as to complete the present invention finally.
The composition of medicine of antimigraine can be treated it is an object of the invention to provide a kind of.
Another object of the present invention just there is provided the preparation method of the composition of medicine.
Medicine selection radix rehmanniae recen of the present invention, rhizoma Gastrodiae, earthworm, safflower, the radix paeoniae rubrathe, Ligusticum wallichii, notopterygium root, chrysanthemum, rough gentian, Asian puccoon, plantain seed, the root of herbaceous peony, windproof, asarum, Chinese cassia tree, the root of kudzu vine, rhizoma cyperi, Radix Angelicae Sinensis, ginseng, Poria cocos, the Radix Astragali, malt, the seed of Oriental arborvitae, prepared rhizome of rehmannia, Divine Comedy, peppermint, schizonepeta, corydalis tuber, scorpio, radix bupleuri, peach kernel, ginger medicine are combined, each efficacy of drugs is caused to produce synergy these drug regimens, so as to the recurrence of fast treating antimigraine.Wherein from being, because its nature and flavor is sweet, to tremble with fear from radix rehmanniae recen, the thoughts of returning home, liver and kidney channel have clearing heat and cooling blood, and yin-nourishing, the function of promoting the production of body fluid controls pyreticosis polydipsia, and yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, Heat Diabetes is spitted blood, bleeding from five sense organs or subcutaneous tissue, spot dermexanthesis.It is, because its nature and flavor is sweet, to put down, enter Liver Channel from rhizoma Gastrodiae, there is ceases wind, the function of arresting convulsion controls dizziness pupil, and head wind headache, extremity numbness, hemiplegia, aphasia, small youngster shies Epilepsy and moves wind.It is, because its nature and flavor is salty, to tremble with fear, enter liver, spleen, lung channel have heat-clearing, soothing the liver, Zhichuan, the function of dredging collateral from earthworm, control hyperpyrexia manic, convulsion, headache due to pathogenic wind-heat, hot eyes, apoplexy and hemiplegia is panted, larynx numbness, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, sore.It is that, because its nature and flavor is pungent, temperature enters the heart, Liver Channel from safflower, there is invigorate blood circulation, the function of stasis eliminatings analgesic, controlling through closing , Disorder lumps in the abdomen, difficult labour, stillborn foetus, disease that postpartum lochia can't go, hemostasis is had a pain, carbuncle swells, injury from falling down.It is, because its is bitter in taste, to be slightly cold, return liver warp has clearing heat and cooling blood, and the function of blood stasis removing analgesic is controlled epidemic heat syndrome and gone mad, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain from the radix paeoniae rubrathe, closed dysmenorrhea , Epilepsy lump in the abdomen stomachache, injury from falling down, carbuncle swells sore.It is that temperature, enter liver, gallbladder channel have promote breath and open depression, dispelled pathogenic wind and remove dampness, the function of promoting blood circulation and stopping pain because its nature and flavor is pungent from Ligusticum wallichii, controls air-cooled headache rotation and swoon, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores.It is that, because its nature and flavor is worked hard, temperature enters bladder, kidney channel, there is a scattered exterior cold, wind-damp dispelling, the function in sharp joint, and cure cold chill from notopterygium root, lossless, wind-cold-dampness arthralgia of having a headache, item strengthening tendons is anxious, joint ache, geomantic omen edema, skin sore.From chrysanthemum be because its nature and flavor sweetness and bitterness, it is cool, enter lung, Liver Channel has dispelling wind, and disappear heat, improving eyesight, the function of removing toxic substances, control headache, dizziness, hot eyes, ambition dysphoria with smothery sensation, furunculosis, pyogenic infections.It is, because its is bitter in taste, to tremble with fear, enter liver, gallbladder channel have purging the liver of pathogenic fire excess fire, except the function of damp-heat in lower-JIAO from rough gentian, controls that Liver Channel excess heat , Jing Epilepsy is manic, encephalitis B, headache, hot eyes, pharyngalgia, jaundice, hot dysentery, carbuncle swells sore, scrotum swells and ache, and private parts is wet to itch.It is, because its nature and flavor earnestly, is trembled with fear, enters percardium, Liver Channel, there is cool blood, to invigorate blood circulation, clearing heat and detoxicating function controls warm macula, jaundice with damp-heat pathogen, purpura from Asian puccoon, tells, is defeated in battle, hematuria, stranguria with turbid discharge, bloody flux, constipation with heat retention, burn, eczema, erysipelas, large carbuncle.It is, because its nature and flavor is sweet, to tremble with fear from plantain seed, enters kidney, bladder warp, favourable water, heat-clearing, improving eyesight, the function of eliminating the phlegm is controlled under urinary obstruction, stranguria with turbid discharge, band, hematuria, summer-heat and damp rush down dysentery, cough ant phlegm, arthritis with fixed pain caused by dampness, hot eyes is hidden from view.It is that cool, enter liver, the spleen channel have nourishing blood and liver because its nature and flavor picric acid from the root of herbaceous peony, is relieved pain in delaying, hold back the cloudy function of receiving sweat, controls under chest and abdomen pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, irregular menstruation, uterine bleeding, band.From it is windproof be the temperature because its property acrid-sweet flavor, enter bladder, lung, the spleen channel, deliver, wind-dispelling wins wet, the function of analgesic, controls and catch cold, and has a headache, and dizzy, Xiang Qiang, wind-cold-dampness arthralgia, skeletal pain, four limbs contraction is anxious, lockjaw.It is that, because its nature and flavor is pungent, temperature enters lung, kidney channel, there is wind-dispelling, function surreptitiously is opened in cold dispelling, water-filling from asarum, controls air-cooled headache, nasosinusitis, analgesic, phlegm and retained fluid coughs inverse, arthralgia pain due to rheumatism.It is that, because its property acrid-sweet flavor, heat enters kidney, spleen, bladder warp from Chinese cassia tree, there is complement sun, warming spleen and stomach, removing internal cold, the function of promoting blood circulation, controls the Yang-function insufficiency of kidneyzang, cold weak pulse of limb, yang depletion collapse, suffer from abdominal pain diarrhea, cold hernia run quickly globefish, waist and knee crymodynia, Jing Bi Disorder lumps in the abdomen, cloudy subcutaneous ulcer, streamer, and empty sun are floating more, heat in the upper and cold in the lower.It is, because its property acrid-sweet flavor, to put down, enter spleen, stomach, there is rising Yang expelling pathogenic factors from muscles and skin, promoting eruption antidiarrheal, the function that relieving restlessness is quenched the thirst controls typhoid fever, warm from the root of kudzu vine, headache, Xiang Qiang, dysphoria with smothery sensation, which disappears, drinks, and diarrhea, dysentery, abnormal pigmentary deposit on the skin examines impermeable, hypertension, angina pectoris, deaf.It is, because the pungent slight bitter of its nature and flavor is done, to put down, enter liver, tri-jiao channel, there is regulating the flow of vital energy Xie Yu, relieve pain the function of menstruation regulating, control under liver-stomach disharmony, depression of QI, the chest and abdomen distending pain in hypochondrium, phlegm and retained fluid feeling of fullness, irregular menstruation, uterine bleeding band from rhizoma cyperi.It is, because its nature and flavor sweet, acrid, warm, to enter the heart, liver, the spleen channel, there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, the function of moisturize laxation from Radix Angelicae Sinensis, irregular menstruation is controlled, Amenorrhea stomachache , Disorder lumps in the abdomen knot gathers, uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, intestinal dryness is difficult just, weight, ulcer sores, metal-inflicted wound, injury from falling down after dysentery characterized by blood in the stool.It is that, because the sweet micro-sweet of its nature and flavor, temperature enters spleen, lung channel, reinforced vital energy from ginseng, prevent prolapse and engender liquid, the function of calming the nerves, it is deficient to control internal lesion caused by overexertion, deficiency of food, burnout, regurgitation and emesis, defecate lingering diarrhea, cough of deficient and syndrome characterized by dyspnea, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition is quenched one's thirst, woman uterine bleeding, infantile chronic fright and perennial and irrecoverable weakness, the disease of all qi-blood-body fluid deficiencies.It is, because its property slightly sweet flavor, to put down, enter the heart, spleen, lung channel from Poria cocos, there is eliminating dampness and diuresis, beneficial spleen and stomach, the function of antitoxic heart-soothing and sedative controls difficult urination oedema distending pain, and phlegm and retained fluid coughs inverse, the sound of vomiting of vomitting, and diarrhea, seminal emission, stranguria with turbid discharge, palpitation with fear is forgetful.It is the tepor because its nature and flavor is sweet from the Radix Astragali, enters lung, the spleen channel, raw to defend solid table with beneficial, inducing diuresis for removing edema, eliminating toxic, the function of myogenic controls spontaneous perspiration, and night sweat, blood-arthralgia, edema, ulcer is not burst or burst and holds back long；Process with the function of having bowl spares benefit, control internal injury overstrain, splenasthenic diarrhea, prolapse of the anus, deficiency of vital energy blood takes off, collapse band and the disease of all laboured breathing deficiency of blood.It is that tepor enters spleen, stomach, has and help digestion because its nature and flavor is sweet from malt, and in, the function of lower gas controls dyspepsia, and abdominal fullness and distention, poor appetite, vomiting and diarrhea, mammary swelling does not disappear.It is, because its nature and flavor is sweet, to put down, enter the heart, liver, the spleen channel, there is mental-tranquilization, the function of relaxing bowel controls palpitation with fear, have a sleepless night from the seed of Oriental arborvitae, seminal emission, night sweat, the function of constipation.It is that tepor enters liver and kidney channel, there is enriching yin, the function of enriching blood because its nature and flavor is sweet from prepared rhizome of rehmannia, it is few to control deficiency of Yin blood, waist knee flaccidity, Cough osteopyrexia, and seminal emission, uterine bleeding, irregular menstruation is quenched one's thirst, number of urinating, deaf, blurred vision.It is, because its nature and flavor sweet, acrid, warm, to enter upright stone tablet, stomach, there is strengthening the spleen and stomach from Divine Comedy, the function of helping digestion in adjusting controls retention of food and drink, feeling of stuffiness in chest abdominal distension, vomiting dysentery, postpartum blood stasis stomachache, the big hard product of children's abdomen.From peppermint be because its nature and flavor it is pungent, it is cool, enter lung, Liver Channel, there is dispelling wind, radiate, ward off dirty, the function of removing toxic substances controls affection of exogenous wind-heat, have a headache, hot eyes, abscess of throat, food stagnation inflatable, aphtha, toothache, sore scabies, urticaria.It is that, because its nature and flavor is pungent, temperature enters lung, Liver Channel, delivered, wind-dispelling, the function of regulating blood condition, fries charcoal hemostasis, and cure cold heating, headache, abscess of throat from schizonepeta, apoplexy lockjaw is spitted blood, and bleeding from five sense organs or subcutaneous tissue is had blood in stool, uterine bleeding, postpartum anemic fainting, carbuncle swells, sore scabies, scrofula.It is that temperature, enter liver, stomach have promoting blood circulation because its nature and flavor is worked hard from corydalis tuber, dissipates the stasis of blood, qi-regulating, the function of analgesic controls all pains of trusted subordinate's waist and knee, irregular menstruation , Disorder lumps in the abdomen, metrorrhagia, postpartum anemic fainting, lochiorrhagia, traumatic injury.It is, because its nature and flavor is salty pungent, to put down from scorpio, it is poisonous, there is wind-dispelling, only convulsion, dredging collateral, the function of removing toxic substances controls convulsion , Dian Epilepsy, and apoplexy, hemiplegia, Kou Yan wai are oblique, antimigraine, arthralgia pain due to rheumatism, lockjaw, scrofula, rubella sore swells.It is, because its bitter in taste, cool, enter liver, gallbladder channel, to have with inducing diaphoresis, soothing the liver, the function of rising Yang controls fevers and chills alternate, and fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower sharp prolapse of the anus, irregular menstruation, metroptosis from radix bupleuri.It is, because its nature and flavor bitter sweet, to put down, enter the heart, liver, large intestine channel, there is the blood-breaking row stasis of blood from peach kernel, moisturizes the function of sliding warp, controlling through closing, Disorder lumps in the abdomen, pyreticosis stores blood, blood-arthralgia, malaria, traumatic injury, blood stasis and swelling pain, the dry constipation of blood.It is that, because its nature and flavor is pungent, temperature enters lung, stomach, the spleen channel, delivered, cold dispelling, preventing or arresting vomiting opens the function of phlegm, and cure cold chill, vomits, and phlegm and retained fluid is breathed with cough, turgor, diarrhea from ginger, the solution tuber of pinellia, rhizoma arisaematis and ichthyophagy crab, birds and beasts meat poisoning.
Embodiment
The drug dose of instant component is also that inventor's process largely gropes to summarize what is drawn, and the consumption of each component all has good therapeutic effect in the range of following weight
10-30 grams of radix rehmanniae recen 10-20 grams of earthworm of 8-22 grams of rhizoma Gastrodiae
4-12 grams of safflower 4-12 grams of Ligusticum wallichii of 10-22 grams of the radix paeoniae rubrathe
8-18 grams of 4-12 grams of chrysanthemum 10-20 crons courage of notopterygium root
10-20 grams of Asian puccoon 10-20 grams of the root of herbaceous peony of 10-22 grams of plantain seed
Windproof 3-12 grams of Chinese cassia tree of 2-8 grams of 10-28 grams of asarum
10-20 grams of root of kudzu vine 4-15 grams of Radix Angelicae Sinensis of 8-12 grams of rhizoma cyperi
10-20 grams of ginseng 6-22 grams of the Radix Astragali of 8-15 grams of Poria cocos
6-18 grams of malt 10-22 grams of prepared rhizome of rehmannia of 10-20 grams of the seed of Oriental arborvitae
5-12 grams of Divine Comedy 10-20 grams of schizonepeta of 12-22 grams of peppermint
8-22 grams of corydalis tuber 8-17 grams of radix bupleuri of 8-15 grams of scorpio
8-14 grams of ginger of 8-22 grams of peach kernel
Wherein, it is preferably
20 grams of radix rehmanniae recen, 15 grams of rhizoma Gastrodiae, 15 grams of earthworm
8 grams of safflower, 15 grams of the radix paeoniae rubrathe, 8 grams of Ligusticum wallichii
8 grams of 10 grams of chrysanthemums of notopterygium root, 15 cron courage
15 grams of Asian puccoon, 13 grams of plantain seed, 20 grams of the root of herbaceous peony
Windproof 6 grams of 15 grams of asarums, 10 grams of Chinese cassia tree
15 grams of the root of kudzu vine, 10 grams of rhizoma cyperi, 10 grams of Radix Angelicae Sinensis
15 grams of ginseng, 9 grams of Poria cocos, 13 grams of the Radix Astragali
10 grams of malt, 15 grams of the seed of Oriental arborvitae, 15 grams of prepared rhizome of rehmannia
10 grams of Divine Comedy, 15 grams of peppermint, 15 grams of schizonepeta
12 grams of corydalis tuber, 10 grams of scorpio, 10 grams of radix bupleuri
10 grams of peach kernel, 10 grams of ginger
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, radix rehmanniae recen：Crude drug is taken, impurity is removed, is cleaned, is slightly moistened, cut sheet, dries, weeds out chip；
2nd, rhizoma Gastrodiae：Gastrodia elata slice is laid on the watch core paper for being jetted through water, put in pot, burn sallow to paper color with slow fire, it is degree constantly to stir tablet to two sides strong yellow；
3rd, earthworm：Impurity is picked, is rinsed with water, is pulled out in time, is dried, segment；
4th, safflower：Net impurity is picked, cauline leaf, base of a fruit head is removed, dries；
5th, the radix paeoniae rubrathe：Crude drug is taken, impurity is removed, size stepping is cleaned, run through, shave, dries, weed out chip；
6th, Ligusticum wallichii：Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, is cut into slices after vexed profit, is dried；
7th, notopterygium root：Impurity is picked, cleans, runs through, cuts into slices, dries；
8th, chrysanthemum：Pick net leaf stalk, anthocaulus and spare impurity；
9th, rough gentian：Impurity is picked, residual stem is removed, is cleaned, is run through rear segment, dry；
10th, Asian puccoon：Clean, run through, cut into slices, dry；
11st, plantain seed：Impurity is picked, spare, empty grain is weeded out；
12nd, the root of herbaceous peony：Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulls out, solarization is dried in the air, profit is uniform to inside and outside humidity, cuts into slices, and dries；
13rd, it is windproof：Residual stem is removed, is soaked in water, is pulled out, section is run through, dries；
14th, asarum：Cleared impurity, is sprayed with water and moistened, and timely segment is dried；
15th, Chinese cassia tree：Net impurity is picked, tertia is scraped off, the used time smashes, or scrapes off tertia, a moment is infiltrated with warm water, section is dried；
16th, the root of kudzu vine：Impurity is picked, is cleaned, is soaked in water, pulls out, run through, section, is dried in time；
17th, rhizoma cyperi：Impurity is picked, particle is ground into, winnow with a dustpan fine, soft fur and smalls；
18th, Radix Angelicae Sinensis：Pick impurity, clean, vexed profit, slightly dry in the air to inside and outside humidity it is suitable when, section is dried；
19th, ginseng：Except removing LU, segment；
20th, Poria cocos：Be soaked in water, clean pull out, it is vexed after, cut into slices, dry；
21st, the Radix Astragali：Net impurity is picked, the root head and hollow the greater of residual is removed, is soaked in water, pulls out, section in time, is dried after running through；
22nd, malt：Taking malt to put in pot, micro- stir-fry is to yellow, and taking-up is cooled；
23rd, the seed of Oriental arborvitae：Net impurity is picked, the shell of residual is removed and plants skin；
24th, prepared rhizome of rehmannia：Take crude drug, steam to surface corvinus, take out, shine to eighty per cant it is dry when, cut into slices, dry；
25th, Divine Comedy：Take wheat bran to sprinkle evenly in cigarette of in hot pot, having waited, Divine Comedy is poured into, fry to yellow, take out, weed out wheat bran, cool；
26th, peppermint：Pick net impurity, remove undesirable root, first by leaf tremble it is lower separately put, stem is then sprayed into clear water, rear segment is run through, dries, then with leaf and even；
27th, schizonepeta：Net impurity is picked, is slightly steeped with water, pulls segment out, dried；
28th, corydalis tuber：Impurity is picked, is soaked in water, is cleaned, solarization is dried in the air, profit is uniform to inside and outside humidity, cuts into slices or smashes；
29th, scorpio：Clear water floats the matter that desalts, and dries, or low baking temperature roasting is used；
30th, radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulls out, section in time, is dried immediately after running through；
31st, peach kernel：Duricrust impurity is removed, puts in boiling water pot and boils to crust microcreping, pull out, in immersion cold water, kind of a skin is removed in stranding, is dried, is winnowed with a dustpan net；
32nd, ginger：Impurity is picked, soil, used time section is cleaned.
2nd, prepare
The radix rehmanniae recen of the weight, rhizoma Gastrodiae, earthworm, safflower, the radix paeoniae rubrathe, Ligusticum wallichii, notopterygium root, chrysanthemum, rough gentian, Asian puccoon, plantain seed, the root of herbaceous peony, windproof, asarum, Chinese cassia tree, the root of kudzu vine, rhizoma cyperi, Radix Angelicae Sinensis, ginseng, Poria cocos, the Radix Astragali, malt, the seed of Oriental arborvitae, prepared rhizome of rehmannia, Divine Comedy, peppermint, schizonepeta, corydalis tuber, scorpio, radix bupleuri, peach kernel, ginger are added into 6 times of amount water, high heat decoction is seethed with excitement 25 minutes, again plus 4 times amount water, again with being cooked by slow fire 20 minutes, produce and take decoction, decoction will be taken and be divided into 4 doses.
Medicine of the present invention has beneficial spleen and stomach, and the function of antitoxic heart-soothing and sedative treats antimigraine instant effect, and short treating period does not recur, and cure rate is high.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these experiments include animal toxicity test and the clinical observation experiment of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Rabbit 20 is taken, male and female dual-purpose, 2.3-2.5kg of body weight is divided to two groups, every group 10, one of which is overdose test group, and another group is normal amount test group.Super quantity group is 25ml/kg, and normal amount is 15ml/kg, and administering mode is administered for administration by gavage, once a day, even served 20 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, medicine is without bad toxic side effect.
The clinical observation material of [test example 2] medicine of the present invention
1st, general information
Accept out-patient 300 for medical treatment.
2nd, diagnostic criteria
Ictal moderate is to severe pulsatile headache, with Nausea and vomiting or photophobia.Physical exertion aggravates headache.Breaking-out is only the dull pain or sense of discomfort of mild to moderate when starting, and serious throbbing pain is reached after a few minutes to a few houres or pain is jumped.About 2/3 is that side property is had a headache, or bilatenal headache, and pain is radiated to neck and shoulder sometimes.
3rd, treatment method
It is early, middle and late daily respectively to take 1 time each taking 1 dose from above-mentioned medicament.14 days are a course for the treatment of, continuously take 4 courses for the treatment of.
4th, efficacy assessment standard
It is effective：Clinical symptom disappearance after treatment, patient recovers normal, and observation half a year is without recidivist；
Take a turn for the better：Clinical symptoms are obviously improved, and antimigraine is progressively recovered；
It is invalid：Clinical part symptom disappears or without change, does not reach improvement standard person.
5th, treatment results
In above-mentioned treatment, with drug therapy migraineur 460 of the present invention, as a result effective 422, obvious effective rate is 91.74%, is taken a turn for the better 28, improvement rate is 6.09%, and invalid 10, total effective rate is 97.83%.
Claims (3)
1. a kind of medicine for treating antimigraine, it is characterised in that：Its bulk drug in the range of following weight is made：
10-30 grams of radix rehmanniae recen 10-20 grams of earthworm of 8-22 grams of rhizoma Gastrodiae
4-12 grams of safflower 4-12 grams of Ligusticum wallichii of 10-22 grams of the radix paeoniae rubrathe
8-18 grams of 4-12 grams of chrysanthemum 10-20 crons courage of notopterygium root
10-20 grams of Asian puccoon 10-20 grams of the root of herbaceous peony of 10-22 grams of plantain seed
Windproof 3-12 grams of Chinese cassia tree of 2-8 grams of 10-28 grams of asarum
10-20 grams of root of kudzu vine 4-15 grams of Radix Angelicae Sinensis of 8-12 grams of rhizoma cyperi
10-20 grams of ginseng 6-22 grams of the Radix Astragali of 8-15 grams of Poria cocos
6-18 grams of malt 10-22 grams of prepared rhizome of rehmannia of 10-20 grams of the seed of Oriental arborvitae
5-12 grams of Divine Comedy 10-20 grams of schizonepeta of 12-22 grams of peppermint
8-22 grams of corydalis tuber 8-17 grams of radix bupleuri of 8-15 grams of scorpio
8-14 grams of ginger of 8-22 grams of peach kernel.
2. medicine according to claim 1, wherein the consumption of each bulk drug is：
20 grams of radix rehmanniae recen, 15 grams of rhizoma Gastrodiae, 15 grams of earthworm
8 grams of safflower, 15 grams of the radix paeoniae rubrathe, 8 grams of Ligusticum wallichii
8 grams of 10 grams of chrysanthemums of notopterygium root, 15 cron courage
15 grams of Asian puccoon, 13 grams of plantain seed, 20 grams of the root of herbaceous peony
Windproof 6 grams of 15 grams of asarums, 10 grams of Chinese cassia tree
15 grams of the root of kudzu vine, 10 grams of rhizoma cyperi, 10 grams of Radix Angelicae Sinensis
15 grams of ginseng, 9 grams of Poria cocos, 13 grams of the Radix Astragali
10 grams of malt, 15 grams of the seed of Oriental arborvitae, 15 grams of prepared rhizome of rehmannia
10 grams of Divine Comedy, 15 grams of peppermint, 15 grams of schizonepeta
12 grams of corydalis tuber, 10 grams of scorpio, 10 grams of radix bupleuri
10 grams of peach kernel, 10 grams of ginger.
3. the preparation method of medicine according to claim 1 or claim 2, it is characterised in that：It comprises the following steps：
（One）Get the raw materials ready
（1）Radix rehmanniae recen：Crude drug is taken, impurity is removed, is cleaned, is slightly moistened, cut sheet, dries, weeds out chip；
（2）Rhizoma Gastrodiae：Gastrodia elata slice is laid on the watch core paper for being jetted through water, put in pot, burn sallow to paper color with slow fire, it is degree constantly to stir tablet to two sides strong yellow；
（3）Earthworm：Impurity is picked, is rinsed with water, is pulled out in time, is dried, segment；
（4）Safflower：Net impurity is picked, cauline leaf, base of a fruit head is removed, dries；
（5）The radix paeoniae rubrathe：Crude drug is taken, impurity is removed, size stepping is cleaned, run through, shave, dries, weed out chip；
（6）Ligusticum wallichii：Impurity is picked, large and small is separated, is soaked in water, solarization is dried in the air, is cut into slices after vexed profit, is dried；
（7）Notopterygium root：Impurity is picked, cleans, runs through, cuts into slices, dries；
（8）Chrysanthemum：Pick net leaf stalk, anthocaulus and spare impurity；
（9）Rough gentian：Impurity is picked, residual stem is removed, is cleaned, is run through rear segment, dry；
（10）Asian puccoon：Clean, run through, cut into slices, dry；
（11）Plantain seed：Impurity is picked, spare, empty grain is weeded out；
（12）The root of herbaceous peony：Impurity is picked, size is separated, is soaked in water to eighty per cant thoroughly, pulls out, solarization is dried in the air, profit is uniform to inside and outside humidity, cuts into slices, and dries；
（13）It is windproof：Residual stem is removed, is soaked in water, is pulled out, section is run through, dries；
（14）Asarum：Cleared impurity, is sprayed with water and moistened, and timely segment is dried；
（15）Chinese cassia tree：Net impurity is picked, tertia is scraped off, the used time smashes, or scrapes off tertia, a moment is infiltrated with warm water, section is dried；
（16）The root of kudzu vine：Impurity is picked, is cleaned, is soaked in water, pulls out, run through, section, is dried in time；
（17）Rhizoma cyperi：Impurity is picked, particle is ground into, winnow with a dustpan fine, soft fur and smalls；
（18）Radix Angelicae Sinensis：Pick impurity, clean, vexed profit, slightly dry in the air to inside and outside humidity it is suitable when, section is dried；
（19）Ginseng：Except removing LU, segment；
（20）Poria cocos：Be soaked in water, clean pull out, it is vexed after, cut into slices, dry；
（21）The Radix Astragali：Net impurity is picked, the root head and hollow the greater of residual is removed, is soaked in water, pulls out, section in time, is dried after running through；
（22）Malt：Taking malt to put in pot, micro- stir-fry is to yellow, and taking-up is cooled；
（23）The seed of Oriental arborvitae：Net impurity is picked, the shell of residual is removed and plants skin；
（24）Prepared rhizome of rehmannia：Take crude drug, steam to surface corvinus, take out, shine to eighty per cant it is dry when, cut into slices, dry；
（25）Divine Comedy：Take wheat bran to sprinkle evenly in cigarette of in hot pot, having waited, Divine Comedy is poured into, fry to yellow, take out, weed out wheat bran, cool；
（26）Peppermint：Pick net impurity, remove undesirable root, first by leaf tremble it is lower separately put, stem is then sprayed into clear water, rear segment is run through, dries, then with leaf and even；
（27）Schizonepeta：Net impurity is picked, is slightly steeped with water, pulls segment out, dried；
（28）Corydalis tuber：Impurity is picked, is soaked in water, is cleaned, solarization is dried in the air, profit is uniform to inside and outside humidity, cuts into slices or smashes；
（29）Scorpio：Clear water floats the matter that desalts, and dries, or low baking temperature roasting is used；
（30）Radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulls out, section in time, is dried immediately after running through；
（31）Peach kernel：Duricrust impurity is removed, puts in boiling water pot and boils to crust microcreping, pull out, in immersion cold water, kind of a skin is removed in stranding, is dried, is winnowed with a dustpan net；
（32）Ginger：Impurity is picked, soil, used time section is cleaned；
（Two）Prepare
The radix rehmanniae recen of the weight, rhizoma Gastrodiae, earthworm, safflower, the radix paeoniae rubrathe, Ligusticum wallichii, notopterygium root, chrysanthemum, rough gentian, Asian puccoon, plantain seed, the root of herbaceous peony, windproof, asarum, Chinese cassia tree, the root of kudzu vine, rhizoma cyperi, Radix Angelicae Sinensis, ginseng, Poria cocos, the Radix Astragali, malt, the seed of Oriental arborvitae, prepared rhizome of rehmannia, Divine Comedy, peppermint, schizonepeta, corydalis tuber, scorpio, radix bupleuri, peach kernel, ginger are added into 6 times of amount water, high heat decoction is seethed with excitement 25 minutes, again plus 4 times amount water, again with being cooked by slow fire 20 minutes, produce and take decoction, decoction will be taken and be divided into 4 doses.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103349692A (en) * | 2013-05-13 | 2013-10-16 | 中国人民解放军第三七一医院 | Traditional Chinese medicine preparation for treating migraine and trigeminal neuralgia |
| CN103751407A (en) * | 2013-12-23 | 2014-04-30 | 孙斌 | Traditional Chinese medicine for treating exopathogenic cold-wind type prosopalgia |
| CN106943490A (en) * | 2017-04-28 | 2017-07-14 | 董早霞 | Wind-expelling pain-stopping Huayu Tang |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101708315A (en) * | 2009-12-04 | 2010-05-19 | 卢速江 | Chinese medicinal preparation for treating headache and preparation method thereof |
| CN101850097A (en) * | 2010-01-19 | 2010-10-06 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating medial headache and migraine and preparation method thereof |
| CN102120023A (en) * | 2010-01-11 | 2011-07-13 | 王继红 | Chinese medicinal preparation for treating migraine and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101708315A (en) * | 2009-12-04 | 2010-05-19 | 卢速江 | Chinese medicinal preparation for treating headache and preparation method thereof |
| CN102120023A (en) * | 2010-01-11 | 2011-07-13 | 王继红 | Chinese medicinal preparation for treating migraine and preparation method thereof |
| CN101850097A (en) * | 2010-01-19 | 2010-10-06 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating medial headache and migraine and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103349692A (en) * | 2013-05-13 | 2013-10-16 | 中国人民解放军第三七一医院 | Traditional Chinese medicine preparation for treating migraine and trigeminal neuralgia |
| CN103349692B (en) * | 2013-05-13 | 2015-04-01 | 中国人民解放军第三七一医院 | Traditional Chinese medicine preparation for treating migraine and trigeminal neuralgia |
| CN103751407A (en) * | 2013-12-23 | 2014-04-30 | 孙斌 | Traditional Chinese medicine for treating exopathogenic cold-wind type prosopalgia |
| CN106943490A (en) * | 2017-04-28 | 2017-07-14 | 董早霞 | Wind-expelling pain-stopping Huayu Tang |
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