CN101693745B - Lucid ganoderma polysaccharide and extraction method thereof as well as cigarette containing lucid ganoderma polysaccharide and preparation method thereof - Google Patents
Lucid ganoderma polysaccharide and extraction method thereof as well as cigarette containing lucid ganoderma polysaccharide and preparation method thereof Download PDFInfo
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- CN101693745B CN101693745B CN2009101898463A CN200910189846A CN101693745B CN 101693745 B CN101693745 B CN 101693745B CN 2009101898463 A CN2009101898463 A CN 2009101898463A CN 200910189846 A CN200910189846 A CN 200910189846A CN 101693745 B CN101693745 B CN 101693745B
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Abstract
The invention discloses a lucid ganoderma polysaccharide and an extraction method thereof as well as a cigarette containing the lucid ganoderma polysaccharide and a preparation method thereof, aiming at solving the technical problem of reducing the harmful ingredients in cigarettes. The lucid ganoderma polysaccharide can be obtained by the following method: drying and grinding lucid ganoderma thallus; leaching in hot water, filtering and concentrating by pressure reduction; adding alcohol and standing still; and finally, treating by centrifugation and filtering. The cigarette containing the lucid ganoderma polysaccharide has the tobacco shred containing the lucid ganoderma polysaccharide with the mass accounting in the tobacco shred. The preparation method of the cigarette containing the lucid ganoderma polysaccharide comprises the following steps: adding water into lucid ganoderma polysaccharide extract to be prepared into solution; spraying the solution onto the tobacco shred; and finally, naturally drying and making into the cigarettes according to the conventional cigarette technology. Compared with the prior art, as the tobacco shred contains the ingredient of lucid ganoderma polysaccharide which can enters the human body along with the main stream smoke and is absorbed by the human body through blood circulation, thus playing the role of resisting tumour, oxidation and aging; furthermore, the smoke of the cigarettes is mellow without impurity gas, so that the invention improves the quality of the cigarettes and reduces the hazard to the human health.
Description
Technical field
The present invention relates to a kind of extract and process for extracting thereof that adds the reduction cigarette harm in the cigarette to, add cigarette of this extract and preparation method thereof, cigarette of particularly a kind of ganoderan and process for extracting thereof, interpolation ganoderan and preparation method thereof.
Background technology
According to a RR of the World Health Organization, the whole world has 1,000,000 people every year at least because smoking and dead prematurely.China pays much attention to the harmful work of falling of cigarette, and since 2005, State Tobacco Monopoly Bureau has organized cigarette hazardness index system and two great special research work of cigarette flavouring humectation, has obtained certain achievement.Like the natural tobacco additive of one Chinese patent application number 200710052295.7 disclosed a kind of flavouring humectations, mainly extract and be prepared from lifting flue gas, the sense of reduction flue gas drying Grosvenor Momordica.One Chinese patent application number 200610128283.3 disclosed Sargassum fusiforme aqueous extracts and in Application in Tobacco; Sargassum fusiforme aqueous extract is joined on the cigarette shreds with feed liquid as cigarette; When burning and sucking cigarette, can produce special chemical component; Obviously improve or improve the quality quality of cigarette, have the effect of promoting the production of body fluid significantly and certain relieving cough function, and can reduce some objectionable constituent in the cigarette mainstream flue gas; Do not change original performance of cigarette, do not change or influence the sucking quality of cigarette.However, the flavouring humectation of cigarette can't be satisfied the many-sided demand of human consumer.
Summary of the invention
The purpose of this invention is to provide cigarette of a kind of ganoderan and process for extracting thereof, interpolation ganoderan and preparation method thereof, the technical problem that solve is to improve flue gas, reduces the objectionable constituent in the cigarette.
The present invention adopts following technical scheme: a kind of ganoderan, and said ganoderan obtains with following method: one, the glossy ganoderma thalline is dried under 30-70 ℃ temperature, be crushed to the 10-100 order; Two, glossy ganoderma thalline powder and the 80-100 ℃ of hot water after will pulverizing was pressed mass ratio 1: 10, and lixiviate is 3 times in hot water, each 5 hours, merges 3 times water extract; Three, filter, filtrate at 0.05Mpa, 60 ℃, concentrating under reduced pressure under the 2 hours time condition; Four, the filtrate volume 5-10 50-98% ethanol doubly after adding concentrates left standstill below 10 ℃ more than 12 hours, 3000 rev/mins, after 30 minutes centrifugal treating, filtered and obtained ganoderan extract.
A kind of process for extracting of ganoderan may further comprise the steps: one, the glossy ganoderma thalline is dried under 30-70 ℃ temperature, be crushed to the 10-100 order; Two, glossy ganoderma thalline powder and the 80-100 ℃ of hot water after will pulverizing was pressed mass ratio 1: 10, and lixiviate is 3 times in hot water, each 5 hours, merges 3 times water extract; Three, filter, filtrate at 0.05Mpa, 60 ℃, concentrating under reduced pressure under the 2 hours time condition; Four, the filtrate volume 5-10 50-98% ethanol doubly after adding concentrates left standstill below 10 ℃ more than 12 hours, 3000 rev/mins, after 30 minutes centrifugal treating, filtered and obtained ganoderan extract.
A kind of cigarette that adds ganoderan has pipe tobacco, contains the ganoderan that accounts for tobacco quality 0.001-10% in the said pipe tobacco; Said ganoderan obtains with following method: one, the glossy ganoderma thalline is dried under 30-70 ℃ temperature, be crushed to the 10-100 order; Two, glossy ganoderma thalline powder and the 80-100 ℃ of hot water after will pulverizing was pressed mass ratio 1: 10, and lixiviate is 3 times in hot water, each 5 hours, merges 3 times water extract; Three, filter, filtrate at 0.05Mpa, 60 ℃, concentrating under reduced pressure under the 2 hours time condition; Four, the filtrate volume 5-10 50-98% ethanol doubly after adding concentrates left standstill below 10 ℃ more than 12 hours, 3000 rev/mins, after 30 minutes centrifugal treating, filtered and obtained ganoderan extract.
Contain the ganoderan that accounts for tobacco quality 0.1% in the pipe tobacco of the present invention.
Contain the ganoderan that accounts for tobacco quality 0.01% in the pipe tobacco of the present invention.
A kind of cigarette that adds ganoderan and preparation method thereof; May further comprise the steps: ganoderan extract is added water be mixed with the solution that mass concentration is 1-10%; The ratio that accounts for tobacco quality 0.001-10% in ganoderan is sprayed onto on the pipe tobacco; Naturally dry, process cigarette by conventional cigarette process again; Following step is used in the extraction of said ganoderan: one, the glossy ganoderma thalline is dried under 30-70 ℃ temperature, be crushed to the 10-100 order; Two, glossy ganoderma thalline powder and the 80-100 ℃ of hot water after will pulverizing was pressed mass ratio 1: 10, and lixiviate is 3 times in hot water, each 5 hours, merges 3 times water extract; Three, filter, filtrate at 0.05Mpa, 60 ℃, concentrating under reduced pressure under the 2 hours time condition; Four, the filtrate volume 5-10 50-98% ethanol doubly after adding concentrates left standstill below 10 ℃ more than 12 hours, 3000 rev/mins, after 30 minutes centrifugal treating, filtered and obtained ganoderan extract.
The present invention compared with prior art contains ganoderan in pipe tobacco, the solvability of ganoderan is good; In smoking process, can get into human body with main flume; Be absorbed by the body through blood circulation, thereby bring into play its antitumor, anti-oxidant, antidotal effect, the pure and mild nothing of the cigarette smoke gas of mixing; Can improve cigarette quality, reduce the hazardness of flue gas human body.
Embodiment
Below in conjunction with embodiment the present invention is done further explain.The process for extracting of ganoderan of the present invention adopts following steps: one, the glossy ganoderma thalline is removed impurity, under 30-70 ℃ temperature, dry, be crushed to the 10-100 order; Two, glossy ganoderma thalline powder and the 80-100 ℃ of hot water after will pulverizing was pressed mass ratio 1: 10, and lixiviate is 3 times in hot water, each 5 hours, merges 3 times water extract; Three, filter, filtrate at 0.05Mpa, 60 ℃, concentrating under reduced pressure under the 2 hours time condition; Four, the filtrate volume 5-10 50-98% ethanol doubly after adding concentrates left standstill below 10 ℃ more than 12 hours, 3000 rev/mins, after 30 minutes centrifugal treating, filtered and obtained ganoderan extract.
The cigarette of interpolation ganoderan of the present invention contains the ganoderan that accounts for tobacco quality 0.001-10% in the pipe tobacco.Said ganoderan extract is added water be mixed with the solution that mass concentration is 1-10%, the ratio that accounts for tobacco quality 0.001-10% in ganoderan evenly is sprayed onto on the pipe tobacco, dries naturally, processes cigarette by conventional cigarette process again.
Embodiment 1, gets the glossy ganoderma thalline that produce in Tai'an, Shandong Province, removes impurity, under 60 ℃ temperature, dries, and is crushed to the 10-100 order; With 100 ℃ of hot water of 10 times of quality, lixiviate 3 times, the time is each 5 hours, merges 3 times water extract, filters; Filtrating is-0.05Mpa, 60 ℃, and concentrating under reduced pressure under the 2 hours time condition adds 95% ethanol, 10 ℃ of 5 times of volumes with the filtrating after concentrating, and leaves standstill 12 hours; 3000 rev/mins, 30 minutes centrifugal treating are filtered, and obtain ganoderan.The preparation mass concentration is 10% solution behind the thin up, evenly is sprayed onto on the pipe tobacco by 0.1% of tobacco quality, dries naturally, processes cigarette by conventional cigarette process.
Embodiment 2, get the glossy ganoderma thalline that produce in Tai'an, Shandong Province, remove impurity, under 50 ℃ temperature, dry, and are crushed to the 10-100 order; With 100 ℃ of hot water of 10 times of quality, lixiviate 3 times, the time is each 5 hours, merges 3 times water extract, filters; Filtrating is 0.05Mpa, 60 ℃, and concentrating under reduced pressure under the 2 hours time condition adds 75% ethanol, 10 ℃ of 10 times of volumes with the filtrating after concentrating, and leaves standstill 12 hours; 3000 rev/mins, 30 minutes centrifugal treating are filtered, and obtain ganoderan.The preparation mass concentration is 8% solution behind the thin up, evenly is sprayed onto on the pipe tobacco by 0.01% of tobacco quality, dries naturally, processes cigarette by conventional cigarette process.
Embodiment 3, get the glossy ganoderma thalline that produce in Tai'an, Shandong Province, remove impurity, under 30 ℃ temperature, dry, and are crushed to the 10-100 order; With 80 ℃ of hot water of 10 times of quality, lixiviate 3 times, the time is each 5 hours, merges 3 times water extract, filters; Filtrating is 0.05Mpa, 60 ℃, and concentrating under reduced pressure under the 2 hours time condition adds 50% ethanol, 10 ℃ of 10 times of volumes with the filtrating after concentrating, and leaves standstill 12 hours; 3000 rev/mins, 30 minutes rotating speed centrifugal treating are filtered, and obtain ganoderan.The preparation mass concentration is 8% solution behind the thin up, evenly is sprayed onto on the pipe tobacco by 0.01% of tobacco quality, dries naturally, processes cigarette by conventional cigarette process.
Embodiment 4, get the glossy ganoderma thalline that produce in Tai'an, Shandong Province, remove impurity, under 70 ℃ temperature, dry; And be crushed to the 10-100 order, and with 80 ℃ of hot water of 10 times of quality, lixiviate 3 times, the time is each 5 hours; Merge 3 times water extract, filter, filtrating is at 0.05Mpa, 60 ℃, concentrating under reduced pressure under the 2 hours time condition; Filtrating after concentrating is added 98% ethanol of 10 times of volumes, below 10 ℃, left standstill 12 hours, 3000 rev/mins, 30 minutes rotating speeds; The time centrifugal treating is filtered, and obtains ganoderan.The preparation mass concentration is 8% solution behind the thin up, evenly is sprayed onto on the pipe tobacco by 0.01% of tobacco quality, dries naturally, processes cigarette by conventional cigarette process.
According to YC/T184-2004 tobacco and tobacco product; The peculiar N-NSC 223080 of tobacco is measured; Press the mensuration of carbon monoxide in the YC/T30-1996 cigarette smoke gas phase, the cigarette that interpolation ganoderan of the present invention is made is compared with the blank cigarette, reduces tobacco-specific nitrosamine 20%, carbon monoxide 15% in the flue gas; Free from extraneous odour, assorted gas, the effect of the Hui Tian that promotes the production of body fluid is arranged, wet one's whistle, eliminating the phlegm.Adopt the method animal toxicity test of GB15193.1-1994 " protective foods security toxicological evaluation standard " can reduce respiratory tract injury.
The present invention has no particular limits the amount that ganoderan joins in the pipe tobacco, and the mouthfeel when mainly looking smoking decides, and the quality of its adding can be 0.001%, the highest 10% of the pipe tobacco that accounts for.
Ganoderan (Ganoderma lucidum Polysaccharide, GLP), prior art has been separated to has kind more than 200; Wherein major part is a beta-glucan, and minority is an alpha-glucan, and polysaccharide chain is made up of three strands of monose chains; It is the three-dimensional formations of a kind of spirrillum; Its three-dimensional configuration and DNA, RNA are similar, and molecular weight is present in the glossy ganoderma cell inwall mostly from hundreds of to hundreds thousand of.Ganoderan is different polysaccharide mostly, promptly except that containing glucose, also contains other monose such as a small amount of pectinose, wood sugar, Fucose, rhamnosyl, semi-lactosi mostly.
The pharmacological action of ganoderan: 1, antitumor action; Ganoderan has suitable inhibition growth activity to Lewis lung cancer and colorectal carcinoma; And can strengthen phagolysis of normal mouse peritoneal macrophage and tumor-bearing mice nk cell (NK cell) activity, thereby enhance immunity function.2, to the regulating effect of immunity, ganoderan can directly stimulate people's CBMC CBMC propagation, and can work in coordination with phytohemagglutinin PHA stimulation CBMC propagation.Ganoderan can significantly increase the number of antibody forming cell PFC in the sheep red blood cell SRBC inductive normal mouse splenocyte.3, antioxidant radical effect, ganoderan all has restraining effect to the generation and the red corpuscle lipid peroxidation of OH-radical, and right-OH has scavenging(action), has the activity of SOD appearance thing, is the important factor that glossy ganoderma delays senility.4, the influence of SOD in the pair cell, ganoderan has tangible enhancement (P＜0.001) to the activity of SOD in the small white mouse red corpuscle.5, function of promoting blood circulation to disperse blood clots; Ganoderan can prolong clotting time of mice significantly; Reduce triglyceride level TG content in the hyperlipemia in mice serum, obviously the time of prolong rats thrombus in vivo formation, the formation that suppresses blood stasis rats in vitro thrombus also reduces the plasma viscosity of blood stasis rat.6, anti-aging effects, ganoderan can obviously strengthen the activity of DNA polymerase α in the Aged Mice splenocyte, and comparing with aged control increases by 44.0% and 58.4% respectively.
Claims (1)
1. a cigarette that adds ganoderan has pipe tobacco, it is characterized in that: contain the ganoderan that accounts for tobacco quality 0.1% or 0.01% in the said pipe tobacco; Said ganoderan obtains with following method: one, the glossy ganoderma thalline is dried under 30-70 ℃ temperature, be crushed to the 10-100 order; Two, glossy ganoderma thalline powder and the 80-100 ℃ of hot water after will pulverizing was pressed mass ratio 1: 10, and lixiviate is 3 times in hot water, each 5 hours, merges 3 times water extract; Three, filter, filtrate at 0.05Mpa, 60 ℃, concentrating under reduced pressure under the 2 hours time condition; Four, the filtrate volume 5-10 50-98% ethanol doubly after adding concentrates left standstill below 10 ℃ more than 12 hours, 3000 rev/mins, after 30 minutes centrifugal treating, filtered and obtained ganoderan extract; The cigarette of said interpolation ganoderan adopts following preparation method to obtain; May further comprise the steps: ganoderan extract is added water be mixed with the solution that mass concentration is 1-10%; The ratio that accounts for tobacco quality 0.1% or 0.01% in ganoderan is sprayed onto on the pipe tobacco; Naturally dry, process cigarette by conventional cigarette process again.
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| CN102068034A (en) * | 2010-12-30 | 2011-05-25 | 贵州中烟工业有限责任公司 | Method for reducing tar and harm of papermaking reconstituted tobacco |
| CN102093486B (en) * | 2011-01-04 | 2012-09-05 | 广东省微生物研究所 | Decolorized ganoderma lucidum polysaccharide extract and method for preparing hand cream by using same |
| CN102120779B (en) * | 2011-04-18 | 2012-07-25 | 夏历 | Efficient extraction technology of ganodorma lucidum fermention mycelium homogeneous polysaccharides |
| CN102295709B (en) * | 2011-07-02 | 2013-04-10 | 上海市农业科学院 | Ganoderma lucidum polysaccharide with light color and high molecular weight, and preparation method thereof |
| CN102697169B (en) * | 2012-07-02 | 2014-08-20 | 广西中烟工业有限责任公司 | Moisturizing and flavor-enhancing additive for cigarettes as well as preparation method and application thereof |
| CN102697170B (en) * | 2012-07-02 | 2015-01-07 | 广西中烟工业有限责任公司 | Aroma-increasing and humidity-preserving additive for cigarettes and preparation method and application thereof |
| GB201213870D0 (en) | 2012-08-03 | 2012-09-19 | British American Tobacco Co | Tobacco extract, preparation thereof |
| CN102793263B (en) * | 2012-08-27 | 2016-01-20 | 福建中烟工业有限责任公司 | The extracting method of white fungus water extracting liquid and the application in tobacco thereof |
| CN103131537B (en) * | 2012-11-13 | 2014-12-03 | 湖北中烟工业有限责任公司 | Preparation method of mycelium volatile oil processed by submerged fermentation of grifola frondosa and application thereof |
| CN104126867B (en) * | 2014-07-18 | 2015-10-21 | 云南中烟工业有限责任公司 | The extracting method of speciosus polysaccharide and the purposes in tobacco product thereof |
| CN104193840B (en) * | 2014-07-31 | 2016-08-31 | 上海市农业科学院 | A kind of lucid ganoderma spore powder polysaccharide and preparation method thereof |
| CN104387495A (en) * | 2014-12-14 | 2015-03-04 | 桂林宏旺菌业股份有限公司 | Preparation method of ganoderma lucidum polysaccharide |
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