CN101678059A - 含大麻素的植物提取物的新用途 - Google Patents

含大麻素的植物提取物的新用途 Download PDF

Info

Publication number
CN101678059A
CN101678059A CN200880016574A CN200880016574A CN101678059A CN 101678059 A CN101678059 A CN 101678059A CN 200880016574 A CN200880016574 A CN 200880016574A CN 200880016574 A CN200880016574 A CN 200880016574A CN 101678059 A CN101678059 A CN 101678059A
Authority
CN
China
Prior art keywords
cannabinoid
containing plant
channel
channels
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200880016574A
Other languages
English (en)
Chinese (zh)
Inventor
V·迪马佐
L·德佩特洛切利斯
A·夏诺莫里洛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GW Pharma Ltd
Original Assignee
GW Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GW Pharma Ltd filed Critical GW Pharma Ltd
Publication of CN101678059A publication Critical patent/CN101678059A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/348—Cannabaceae
    • A61K36/3482—Cannabis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
CN200880016574A 2007-04-19 2008-04-17 含大麻素的植物提取物的新用途 Pending CN101678059A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0707610A GB2448535A (en) 2007-04-19 2007-04-19 New use for cannabinoid-containing plant extracts
GB0707610.2 2007-04-19
PCT/GB2008/001359 WO2008129258A1 (en) 2007-04-19 2008-04-17 New use for cannabinoid-containing plant extracts

Publications (1)

Publication Number Publication Date
CN101678059A true CN101678059A (zh) 2010-03-24

Family

ID=38135105

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880016574A Pending CN101678059A (zh) 2007-04-19 2008-04-17 含大麻素的植物提取物的新用途

Country Status (8)

Country Link
US (1) US20100249223A1 (https=)
EP (1) EP2146731B1 (https=)
JP (1) JP5775300B2 (https=)
CN (1) CN101678059A (https=)
CA (1) CA2684562A1 (https=)
ES (1) ES2717839T3 (https=)
GB (1) GB2448535A (https=)
WO (1) WO2008129258A1 (https=)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102869356A (zh) * 2010-03-12 2013-01-09 Gw药品有限公司 治疗癌症中的植物大麻素
CN103533930A (zh) * 2011-05-20 2014-01-22 Gw药品有限公司 用于治疗神经性疼痛的大麻素类化合物
CN102083430B (zh) * 2008-06-04 2015-10-07 Gw药品有限公司 大麻类化合物组合物在制备治疗脑部肿瘤药物中的用途
CN105477635A (zh) * 2014-09-15 2016-04-13 中国人民解放军第二军医大学 一种治疗持续性慢性疼痛的靶点和药物
TWI577373B (zh) * 2011-09-29 2017-04-11 Ｇｗ伐瑪有限公司 包括植物大麻素次大麻二酚（ｃｂｄｖ）及大麻二酚（ｃｂｄ）之藥學組成物
CN107846936A (zh) * 2015-07-22 2018-03-27 芙图法尔马国际有限公司 蜜蜂可摄取组成物及使用其生产蜂蜜的方法与由此生产的蜂蜜
CN108697665A (zh) * 2015-09-30 2018-10-23 乔治·爱德华·霍格 局部镇痛性疼痛缓解制剂、其制备和使用方法
CN109641022A (zh) * 2016-06-15 2019-04-16 奥海能量公益公司 用于减少氧化应激的方法和组合物
CN109939014A (zh) * 2017-12-20 2019-06-28 汉义生物科技（北京）有限公司 一种含有大麻素的口气清新剂
CN110913839A (zh) * 2017-05-22 2020-03-24 Gbs全球生物制药公司 靶向trpv1的含月桂烯和大麻素的组合物
CN112543633A (zh) * 2018-05-22 2021-03-23 Gbs全球生物制药公司 Trpv1调节中使用的大麻素和/或萜烯
CN115887440A (zh) * 2016-10-11 2023-04-04 Gbs全球生物制药公司 用于治疗神经退行性疾病的含有大麻素的复合混合物
CN119912407A (zh) * 2023-10-31 2025-05-02 北京红惠新医药科技有限公司 大麻二酚环氧化物的制备方法及应用

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7674594B2 (en) 2006-07-27 2010-03-09 Redpoint Bio Corporation Screening assay for inhibitors of TRPA1 activation by a lower alkyl phenol
US9084771B2 (en) 2007-05-17 2015-07-21 Sutter West Bay Hospitals Methods and compositions for treating cancer
KR101063352B1 (ko) 2008-11-28 2011-09-07 고려대학교 산학협력단 Ｔｒｐａ１ 활성 억제 약물 및 이의 활용
DE102010002558A1 (de) 2009-11-20 2011-06-01 Symrise Ag Verwendung physiologischer Kühlwirkstoffe und Mittel enthaltend solche Wirkstoffe
TWI583374B (zh) 2010-03-30 2017-05-21 Ｇｗ伐瑪有限公司 使用植物大麻素次大麻二酚（ｃｂｄｖ）來治療癲癇之用途
US8445034B1 (en) 2010-11-02 2013-05-21 Albert L Coles, Jr. Systems and methods for producing organic cannabis tincture
GB2487712B (en) 2011-01-04 2015-10-28 Otsuka Pharma Co Ltd Use of the phytocannabinoid cannabidiol (CBD) in combination with a standard anti-epileptic drug (SAED) in the treatment of epilepsy
JP6061448B2 (ja) * 2011-03-10 2017-01-18 株式会社マンダム 被験物質の評価方法
KR20120111125A (ko) * 2011-03-31 2012-10-10 주식회사한국전통의학연구소 마자인 추출물을 포함하는 신장암 치료용 조성물 및 건강 기능성 식품
GB2494461A (en) * 2011-09-12 2013-03-13 Gw Pharma Ltd Phytocannabinoids for use in the treatment of invasive cancers or metastases
GB201117956D0 (en) * 2011-10-18 2011-11-30 Otsuka Pharma Co Ltd Phytocannabinoids for use in the treatment of breast cancer
WO2013164824A1 (en) 2012-05-03 2013-11-07 Magdent Ltd. Bone enhancement device and method
NL2009671C2 (en) * 2012-10-19 2014-04-23 Fytagoras B V New antiviral use for acidic cannabinoids.
GB2516814B (en) 2013-06-19 2016-08-31 Otsuka Pharma Co Ltd Use of phytocannabinoids for increasing radiosensitivity in the treatment of cancer
US10774288B2 (en) 2013-09-18 2020-09-15 The Werc Shop, LLC Terpene-based compositions, processes, methodologies for creation and products thereby
US9220294B2 (en) 2014-02-11 2015-12-29 Timothy McCullough Methods and devices using cannabis vapors
US10821240B2 (en) 2014-02-11 2020-11-03 Vapor Cartridge Technology Llc Methods and drug delivery devices using cannabis
US9380813B2 (en) 2014-02-11 2016-07-05 Timothy McCullough Drug delivery system and method
JP6673895B2 (ja) 2014-03-21 2020-03-25 エスティー アンド ティー インターナショナル，インコーポレイティド アサ属抽出方法及び組成物
US9186386B2 (en) 2014-04-17 2015-11-17 Gary J. Speier Pharmaceutical composition and method of manufacturing
US9044390B1 (en) 2014-04-17 2015-06-02 Gary J. Speier Pharmaceutical composition and method of manufacturing
GB2530001B (en) 2014-06-17 2019-01-16 Gw Pharma Ltd Use of cannabidiol in the reduction of convulsive seizure frequency in treatment-resistant epilepsy
GB2527599A (en) 2014-06-27 2015-12-30 Gw Pharma Ltd Use of 7-OH-Cannabidiol (7-OH-CBD) and/or 7-OH-Cannabidivarin (7-OH-CBDV) in the treatment of epilepsy
GB2527590A (en) * 2014-06-27 2015-12-30 Otsuka Pharma Co Ltd Active pharmaceutical ingredient (API) comprising cannabinoids for use in the treatment of cancer
GB2531282A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabinoids in the treatment of epilepsy
GB2531278A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabidiol in the treatment of intractable epilepsy
GB2531281A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabidiol in the treatment of intractable epilepsy
CN107205960A (zh) 2014-10-21 2017-09-26 联合大麻公司 大麻提取物及其制备和使用方法
IL253664B (en) 2015-01-31 2022-09-01 Constance Therapeutics Inc Production method for extracting oil from cannabis and preparations
US10238745B2 (en) 2015-01-31 2019-03-26 Constance Therapeutics, Inc. Cannabinoid composition and products including α-tocopherol
BR112017018316A2 (pt) 2015-02-27 2018-04-17 Ebbu Llc composições compreendendo combinações de canabinoides purificados, com pelo menos um flavonoide, terpeno ou mineral
US12303541B2 (en) 2015-04-01 2025-05-20 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Erodium crassifolium L'Her plant extracts and uses thereof
EP3277260B1 (en) 2015-04-01 2021-05-12 The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) Erodium crassifolium l'her plant extracts and uses thereof
GB2539472A (en) 2015-06-17 2016-12-21 Gw Res Ltd Use of cannabinoids in the treatment of epilepsy
GB2541191A (en) 2015-08-10 2017-02-15 Gw Pharma Ltd Use of cannabinoids in the treatment of epilepsy
GB2542797A (en) * 2015-09-29 2017-04-05 Gw Pharma Ltd Use of cannabinoids in the treatment of inflammatory skin diseases
CA3006182A1 (en) 2015-11-24 2017-06-01 Constance Therapeutics, Inc. Cannabis oil compositions and methods for preparation thereof
GB2548873B (en) 2016-03-31 2020-12-02 Gw Res Ltd Use of Cannabidiol in the Treatment of SturgeWeber Syndrome
US10499584B2 (en) 2016-05-27 2019-12-10 New West Genetics Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles
WO2018000094A1 (en) 2016-06-29 2018-01-04 CannScience Innovations Inc. Decarboxylated cannabis resins, uses thereof and methods of making same
GB2551986A (en) 2016-07-01 2018-01-10 Gw Res Ltd Parenteral formulations
GB2551987A (en) 2016-07-01 2018-01-10 Gw Res Ltd Oral cannabinoid formulations
GB2553139A (en) 2016-08-25 2018-02-28 Gw Res Ltd Use of cannabinoids in the treatment of multiple myeloma
US12485129B2 (en) 2016-08-29 2025-12-02 Canopy Growth Corporation Water soluble compositions comprising purified cannabinoids
WO2018044953A1 (en) 2016-08-29 2018-03-08 Ebbu, LLC Water soluble compositions comprising purified cannabinoids
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
GB2557921A (en) 2016-12-16 2018-07-04 Gw Res Ltd Use of cannabinoids in the treatment of angelman syndrome
GB2559774B (en) 2017-02-17 2021-09-29 Gw Res Ltd Oral cannabinoid formulations
GB2560019A (en) 2017-02-27 2018-08-29 Gw Res Ltd Use of cannabinoids in the treatment of leukaemia
EP3592346A4 (en) 2017-03-05 2020-12-30 The State of Isreal, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER
GB2564383B (en) 2017-06-23 2021-04-21 Gw Res Ltd Use of cannabidiol in the treatment of tumours assoicated with Tuberous Sclerosis Complex
EP3675809B1 (de) 2017-08-31 2023-09-27 Basf Se Verwendung physiologischer kühlwirkstoffe und mittel enthaltend solche wirkstoffe
GB2568929A (en) 2017-12-01 2019-06-05 Gw Res Ltd Use of cannabinoids in the treatment of epilepsy
GB2569961B (en) 2018-01-03 2021-12-22 Gw Res Ltd Pharmaceutical
EP3745884A1 (en) 2018-01-31 2020-12-09 Canopy Holdings, Llc Hemp powder
CN112969452A (zh) 2018-04-09 2021-06-15 艾乐文特科学公司 用于治疗动物疼痛的大麻提取物
WO2019222459A1 (en) * 2018-05-18 2019-11-21 Diverse Biotech, Inc. Cannabinoid preparations and therapeutic uses
CA3104795A1 (en) * 2018-06-28 2020-01-02 Canopy Growth Corporation Compositions and methods for agonizing the cb2 receptor
CA3119729A1 (en) 2018-10-10 2020-04-16 Treehouse Biotech, Inc. Synthesis of cannabigerol
US20220233463A1 (en) * 2019-05-16 2022-07-28 Buzzelet Development And Technologies Ltd. Local anesthetic comprising a trp channel modulator
EP4030941A1 (en) 2019-09-16 2022-07-27 Vapor Cartridge Technology LLC Drug delivery system with stackable substrates
CN112569220B (zh) * 2019-09-30 2023-03-07 云南汉盟制药有限公司 四氢次大麻酚在制备用于治疗肺动脉高压药物中的应用及含有四氢次大麻酚的药物组合物
US12409131B2 (en) 2019-10-03 2025-09-09 Pike Therapeutics Usa, Inc. Transdermal delivery of dronabinol
CN114650809A (zh) 2019-10-03 2022-06-21 斯塔顿治疗公司 屈大麻酚的透皮递送
CA3155176A1 (en) 2019-10-11 2021-04-15 Pike Therapeutics, Inc., 1219014 B.C. Ltd. Transdermal compositions comprising cannabidiol (cbd) for use in the treatment of seizure disorders
US12016829B2 (en) 2019-10-11 2024-06-25 Pike Therapeutics Inc. Pharmaceutical composition and method for treating seizure disorders
CA3155181A1 (en) 2019-10-14 2021-04-22 Pike Therapeutics, Inc., 1219014 B.C. Ltd. Transdermal delivery of cannabidiol
US12121617B2 (en) 2019-10-14 2024-10-22 Pike Therapeutics Inc. Transdermal delivery of cannabidiol
GB202002754D0 (en) 2020-02-27 2020-04-15 Gw Res Ltd Methods of treating tuberous sclerosis complex with cannabidiol and everolimus
AU2021240053A1 (en) * 2020-03-20 2022-11-03 The Queen's Medical Center Cannabinoid compositions
JP2023523275A (ja) * 2020-04-24 2023-06-02 ジュス・ライフ・サイエンシーズ・インコーポレイテッド 疼痛管理のためのカンナビクロメン製剤
KR102433007B1 (ko) * 2020-07-28 2022-08-16 동의대학교 산학협력단 산골취 추출물을 포함하는 신경병증성 통증 예방 및 개선용 조성물
US11160757B1 (en) 2020-10-12 2021-11-02 GW Research Limited pH dependent release coated microparticle cannabinoid formulations
US12440454B2 (en) 2022-02-01 2025-10-14 Portland Technology Holdings Llc Pharmaceutical compositions containing hemp extract for administration to felines and related methods
WO2024033521A1 (en) 2022-08-12 2024-02-15 GW Research Limited Oral solid dosage forms comprising cannabinoids

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837228A (en) * 1979-05-31 1989-06-06 The University Of Mississippi Antiinflammatory and antimicrobial compounds and compositions
JPH0426622A (ja) * 1990-05-18 1992-01-29 Tsumura & Co 制癌剤
US5939429A (en) * 1997-09-30 1999-08-17 Virginia Commonwealth University Cardiovascular uses of cannabinoid compounds
GB9807639D0 (en) * 1998-04-14 1998-06-10 Kennedy Rheumatology Inst Anti-inflammatory agents
US6403126B1 (en) * 1999-05-26 2002-06-11 Websar Innovations Inc. Cannabinoid extraction method
US6949582B1 (en) * 1999-05-27 2005-09-27 Wallace Walter H Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment
GB2377633A (en) * 2001-05-11 2003-01-22 Gw Pharmaceuticals Ltd Pharmaceutical compositions comprising the cannabinoids THC and CBD
DK1361864T3 (en) * 2001-02-14 2014-03-03 Gw Pharma Ltd FLYLDENDE SPRAY FORMULATIONS FOR buccal administration of cannabinoids
US7025992B2 (en) * 2001-02-14 2006-04-11 Gw Pharma Limited Pharmaceutical formulations
CH695661A5 (de) * 2001-03-06 2006-07-31 Forsch Hiscia Ver Fuer Krebsfo Pharmazeutische Zusammensetzung.
WO2003087158A2 (en) * 2002-04-16 2003-10-23 Bayer Healthcare Ag Regulation of human transient receptor potential channel
GB2394894B (en) * 2002-11-04 2005-08-31 G W Pharma Ltd New use for pharmaceutical composition
GB2414933B (en) * 2004-06-08 2009-07-15 Gw Pharma Ltd Cannabinoid compositions for the treatment of disease and/or symptoms in arthritis
GB2418612A (en) * 2004-10-01 2006-04-05 Gw Pharma Ltd Inhibition of tumour cell migration with cannabinoids
US7597910B2 (en) * 2005-08-20 2009-10-06 Slgm Medical Research Institute Compositions and methods for treating prostate disorders
AU2006308914A1 (en) * 2005-10-31 2007-05-10 Janssen Pharmaceutica N.V. Compositions and methods for identifying modulators of TRPV2
GB2432312A (en) * 2005-11-01 2007-05-23 Gw Pharma Ltd Pharmaceutical compositions for the treatment of pain

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NAPLES, ITALY: "《www.cannabidiol.info》", 1 June 2006 *

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102083430B (zh) * 2008-06-04 2015-10-07 Gw药品有限公司 大麻类化合物组合物在制备治疗脑部肿瘤药物中的用途
CN102869356A (zh) * 2010-03-12 2013-01-09 Gw药品有限公司 治疗癌症中的植物大麻素
CN103533930A (zh) * 2011-05-20 2014-01-22 Gw药品有限公司 用于治疗神经性疼痛的大麻素类化合物
TWI577373B (zh) * 2011-09-29 2017-04-11 Ｇｗ伐瑪有限公司 包括植物大麻素次大麻二酚（ｃｂｄｖ）及大麻二酚（ｃｂｄ）之藥學組成物
CN105477635A (zh) * 2014-09-15 2016-04-13 中国人民解放军第二军医大学 一种治疗持续性慢性疼痛的靶点和药物
US11426434B2 (en) 2015-07-22 2022-08-30 Phytopharma International Ltd. Bee-ingestible compositions, methods of using same for producing honey and honey produced thereby
CN107846936B (zh) * 2015-07-22 2021-06-01 芙图法尔马国际有限公司 蜜蜂可摄取组成物及使用其生产蜂蜜的方法与由此生产的蜂蜜
CN107846936A (zh) * 2015-07-22 2018-03-27 芙图法尔马国际有限公司 蜜蜂可摄取组成物及使用其生产蜂蜜的方法与由此生产的蜂蜜
CN108697665A (zh) * 2015-09-30 2018-10-23 乔治·爱德华·霍格 局部镇痛性疼痛缓解制剂、其制备和使用方法
CN109641022A (zh) * 2016-06-15 2019-04-16 奥海能量公益公司 用于减少氧化应激的方法和组合物
CN115887440A (zh) * 2016-10-11 2023-04-04 Gbs全球生物制药公司 用于治疗神经退行性疾病的含有大麻素的复合混合物
CN110913839A (zh) * 2017-05-22 2020-03-24 Gbs全球生物制药公司 靶向trpv1的含月桂烯和大麻素的组合物
US11944593B2 (en) 2017-05-22 2024-04-02 Gbs Global Biopharma, Inc. Myrcene-containing complex mixtures targeting TRPV1
CN109939014A (zh) * 2017-12-20 2019-06-28 汉义生物科技（北京）有限公司 一种含有大麻素的口气清新剂
CN112543633A (zh) * 2018-05-22 2021-03-23 Gbs全球生物制药公司 Trpv1调节中使用的大麻素和/或萜烯
CN119912407A (zh) * 2023-10-31 2025-05-02 北京红惠新医药科技有限公司 大麻二酚环氧化物的制备方法及应用

Also Published As

Publication number Publication date
CA2684562A1 (en) 2008-10-30
WO2008129258A1 (en) 2008-10-30
GB0707610D0 (en) 2007-05-30
US20100249223A1 (en) 2010-09-30
GB2448535A (en) 2008-10-22
JP2010524912A (ja) 2010-07-22
EP2146731A1 (en) 2010-01-27
EP2146731B1 (en) 2019-01-16
JP5775300B2 (ja) 2015-09-09
ES2717839T3 (es) 2019-06-25

Similar Documents

Publication Publication Date Title
CN101678059A (zh) 含大麻素的植物提取物的新用途
Li et al. Intranasal pretreatment with Z-Ligustilide, the main volatile component of Rhizoma Chuanxiong, confers prophylaxis against cerebral ischemia via Nrf2 and HSP70 signaling pathways
Mousa et al. Repositioning of dipeptidyl peptidase-4 inhibitors and glucagon like peptide-1 agonists as potential neuroprotective agents
Stinson et al. Modulation of transient receptor potential (TRP) channels by plant derived substances used in over-the-counter cough and cold remedies
Zhou et al. Allicin protects rat cortical neurons against mechanical trauma injury by regulating nitric oxide synthase pathways
Xu et al. Engeletin alleviates cerebral ischemia reperfusion‐induced neuroinflammation via the HMGB1/TLR4/NF‐κB network
Hu et al. A combined water extract of frankincense and myrrh alleviates neuropathic pain in mice via modulation of TRPV1
Xu et al. Active components of Bupleurum chinense and Angelica biserrata showed analgesic effects in formalin induced pain by acting on Nav1. 7
Zhou et al. Phenylbutyrate prevents disruption of blood-spinal cord barrier by inhibiting endoplasmic reticulum stress after spinal cord injury
Siu et al. Topical application of Chinese herbal medicine DAEP relieves the osteoarthritic knee pain in rats
Paland et al. Cannabis and rheumatoid arthritis: A scoping review evaluating the benefits, risks, and future research directions
CN102380015A (zh) 治疗类风湿性关节炎的药物组合物及其制备方法和用途
WO2013173941A1 (en) Peptide and the use thereof
Song et al. Jinmaitong ameliorates diabetes-induced peripheral neuropathy in rats through Wnt/β-catenin signaling pathway
Smith et al. Aromatic ointments for the common cold: what does the science say?
Ashton et al. The case for cannabinoid cb1 receptors as a target for bronchodilator therapy for β-agonist resistant asthma
Baker et al. An adult rat spinal cord contusion model of sensory axon degeneration: the estrus cycle or a preconditioning lesion do not affect outcome
EP4601630A1 (en) Selective hypothalamus permeable hdac6 inhibitors for treatment of leptin-resistant obesity
Yu et al. α-Cyperone safeguards against cerebral ischaemia‒reperfusion injury through the activation of the Nrf2 signalling pathway
HK1139877B (en) Cannabinoid-containing plant extracts for the treatment of prostate cancer
HK1139877A (en) Cannabinoid-containing plant extracts for the treatment of prostate cancer
Babayeva et al. Marijuana compounds: a non-conventional therapeutic approach to epilepsy in children
Ross The analgesic effects of cannabis
Chauhan et al. The potential of cannabis in pain management
CN110876796A (zh) 一种用于治疗痛风急性发作的中药组合物及其制备方法和应用

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C12 Rejection of a patent application after its publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20100324