CN1016060B - 2-苯并咪唑基烷硫基(或亚硫酰基或磺酰基)衍生物的制备方法 - Google Patents

2-苯并咪唑基烷硫基(或亚硫酰基或磺酰基)衍生物的制备方法

Info

Publication number
CN1016060B
CN1016060B CN87100363A CN87100363A CN1016060B CN 1016060 B CN1016060 B CN 1016060B CN 87100363 A CN87100363 A CN 87100363A CN 87100363 A CN87100363 A CN 87100363A CN 1016060 B CN1016060 B CN 1016060B
Authority
CN
China
Prior art keywords
formula
compound
represent
meaning
indicated above
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CN87100363A
Other languages
English (en)
Chinese (zh)
Other versions
CN87100363A (zh
Inventor
约尔迪·弗里戈拉·康斯坦萨
奥戈斯托·科洛姆波·彼诺尔
朱安·帕里斯·科罗米纳斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Publication of CN87100363A publication Critical patent/CN87100363A/zh
Publication of CN1016060B publication Critical patent/CN1016060B/zh
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CN87100363A 1986-01-20 1987-01-20 2-苯并咪唑基烷硫基(或亚硫酰基或磺酰基)衍生物的制备方法 Expired CN1016060B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8600695A FR2593178B1 (fr) 1986-01-20 1986-01-20 Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments.
FR8600695 1986-01-20

Publications (2)

Publication Number Publication Date
CN87100363A CN87100363A (zh) 1987-09-02
CN1016060B true CN1016060B (zh) 1992-04-01

Family

ID=9331254

Family Applications (1)

Application Number Title Priority Date Filing Date
CN87100363A Expired CN1016060B (zh) 1986-01-20 1987-01-20 2-苯并咪唑基烷硫基(或亚硫酰基或磺酰基)衍生物的制备方法

Country Status (22)

Country Link
US (1) US4791114A (enExample)
EP (1) EP0234980B1 (enExample)
JP (1) JPS62181274A (enExample)
KR (1) KR890002291B1 (enExample)
CN (1) CN1016060B (enExample)
AT (1) ATE80625T1 (enExample)
AU (1) AU587680B2 (enExample)
BR (1) BR8700191A (enExample)
CA (1) CA1296336C (enExample)
DD (1) DD259401A5 (enExample)
DE (2) DE234980T1 (enExample)
DK (1) DK23887A (enExample)
ES (1) ES2003658A6 (enExample)
FR (1) FR2593178B1 (enExample)
GR (2) GR880300076T1 (enExample)
HU (1) HU197566B (enExample)
NO (1) NO170931C (enExample)
PL (1) PL154487B1 (enExample)
PT (1) PT84141B (enExample)
SU (1) SU1586513A3 (enExample)
YU (1) YU45932B (enExample)
ZA (1) ZA87343B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK8600939A (enExample) * 1985-03-05 1986-09-06
SE8804628D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New compounds
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
ES2171116B1 (es) * 2000-04-14 2003-08-01 Esteve Quimica Sa Procedimiento para la obtencion de derivados de (((piridil sustituido)metil)tio)bencimidazol.
GB0108592D0 (en) * 2001-04-05 2001-05-23 Merck Sharp & Dohme Therapeutic agents
CA2756104C (en) * 2009-04-09 2013-01-22 Arigen Pharmaceuticals, Inc. Pyridine thio derivative, and pharmaceutical composition which contains same and has anti-helicobacter pylori action
BR112017003745A2 (pt) 2014-08-29 2017-12-05 Tes Pharma S R L inibidores de semialdeído descarboxilase de ácido alfa-amino-beta-carboximucônico

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (enExample) * 1968-10-21 1971-06-03
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
US4619944A (en) * 1981-06-01 1986-10-28 Usv Pharmaceutical Corporation Antihypertensive compounds

Also Published As

Publication number Publication date
PL263733A1 (en) 1988-07-07
CA1296336C (fr) 1992-02-25
JPS62181274A (ja) 1987-08-08
KR890002291B1 (ko) 1989-06-28
NO870228L (no) 1987-07-21
DK23887D0 (da) 1987-01-16
NO170931C (no) 1992-12-30
KR870007157A (ko) 1987-08-17
DD259401A5 (de) 1988-08-24
GR880300076T1 (en) 1988-12-16
ES2003658A6 (es) 1988-11-01
FR2593178A1 (fr) 1987-07-24
PL154487B1 (en) 1991-08-30
YU45932B (sh) 1992-09-07
BR8700191A (pt) 1987-12-08
DK23887A (da) 1987-07-21
DE234980T1 (de) 1988-02-25
NO170931B (no) 1992-09-21
FR2593178B1 (fr) 1988-04-29
SU1586513A3 (ru) 1990-08-15
EP0234980A1 (fr) 1987-09-02
HUT44781A (en) 1988-04-28
DE3781703T2 (de) 1993-02-18
US4791114A (en) 1988-12-13
YU6087A (en) 1988-08-31
PT84141A (fr) 1987-02-01
NO870228D0 (no) 1987-01-20
PT84141B (pt) 1989-05-31
GR3006109T3 (enExample) 1993-06-21
AU587680B2 (en) 1989-08-24
ZA87343B (en) 1987-08-26
CN87100363A (zh) 1987-09-02
AU6762187A (en) 1987-07-23
HU197566B (en) 1989-04-28
DE3781703D1 (de) 1992-10-22
ATE80625T1 (de) 1992-10-15
EP0234980B1 (fr) 1992-09-16

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