CN101544638B - 乳酸咯萘啶及其药物组合物 - Google Patents

乳酸咯萘啶及其药物组合物 Download PDF

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Publication number
CN101544638B
CN101544638B CN2009101363868A CN200910136386A CN101544638B CN 101544638 B CN101544638 B CN 101544638B CN 2009101363868 A CN2009101363868 A CN 2009101363868A CN 200910136386 A CN200910136386 A CN 200910136386A CN 101544638 B CN101544638 B CN 101544638B
Authority
CN
China
Prior art keywords
compound
artemisinin
pharmaceutical composition
formula
malaridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2009101363868A
Other languages
English (en)
Chinese (zh)
Other versions
CN101544638A (zh
Inventor
郑一敏
周慧
胥修英
韩玉梅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chongqing Tongtian Pharmaceutical Co Ltd
Original Assignee
Chongqing Tongtian Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chongqing Tongtian Pharmaceutical Co Ltd filed Critical Chongqing Tongtian Pharmaceutical Co Ltd
Priority to CN2009101363868A priority Critical patent/CN101544638B/zh
Publication of CN101544638A publication Critical patent/CN101544638A/zh
Priority to PCT/CN2010/000655 priority patent/WO2010130147A1/fr
Application granted granted Critical
Publication of CN101544638B publication Critical patent/CN101544638B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2009101363868A 2009-05-12 2009-05-12 乳酸咯萘啶及其药物组合物 Expired - Fee Related CN101544638B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN2009101363868A CN101544638B (zh) 2009-05-12 2009-05-12 乳酸咯萘啶及其药物组合物
PCT/CN2010/000655 WO2010130147A1 (fr) 2009-05-12 2010-05-10 Lactate de pyronaridine, composition pharmaceutique et son utilisation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009101363868A CN101544638B (zh) 2009-05-12 2009-05-12 乳酸咯萘啶及其药物组合物

Publications (2)

Publication Number Publication Date
CN101544638A CN101544638A (zh) 2009-09-30
CN101544638B true CN101544638B (zh) 2012-05-30

Family

ID=41192034

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009101363868A Expired - Fee Related CN101544638B (zh) 2009-05-12 2009-05-12 乳酸咯萘啶及其药物组合物

Country Status (2)

Country Link
CN (1) CN101544638B (fr)
WO (1) WO2010130147A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101544638B (zh) * 2009-05-12 2012-05-30 重庆通天药业有限公司 乳酸咯萘啶及其药物组合物
WO2012154879A2 (fr) 2011-05-09 2012-11-15 Van Andel Research Institute Inhibiteurs d'autophagie
CN115515955A (zh) * 2020-04-17 2022-12-23 默克专利股份公司 4-[(7-氯-2-甲氧基苯并[b][1,5]萘啶-10-基)氨基]-2,6-双(吡咯烷-1-基甲基)苯酚及其盐的结晶形式
CN113350334A (zh) * 2021-02-05 2021-09-07 中国中医科学院中药研究所 一种含有双氢青蒿素的抗疟药物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1109546C (zh) * 1998-06-17 2003-05-28 中国疾病预防控制中心寄生虫病预防控制研究所 青蒿素类药物与咯萘啶的复方制剂抗疟药物
KR100623322B1 (ko) * 2004-11-02 2006-09-19 신풍제약주식회사 경구투여용 항말라리아 배합 제제 및 그의 제조방법
CN101544638B (zh) * 2009-05-12 2012-05-30 重庆通天药业有限公司 乳酸咯萘啶及其药物组合物

Also Published As

Publication number Publication date
CN101544638A (zh) 2009-09-30
WO2010130147A1 (fr) 2010-11-18

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120530

Termination date: 20170512