CN101490057B - 制造光活性剂的组合物和方法 - Google Patents

制造光活性剂的组合物和方法 Download PDF

Info

Publication number
CN101490057B
CN101490057B CN2007800274940A CN200780027494A CN101490057B CN 101490057 B CN101490057 B CN 101490057B CN 2007800274940 A CN2007800274940 A CN 2007800274940A CN 200780027494 A CN200780027494 A CN 200780027494A CN 101490057 B CN101490057 B CN 101490057B
Authority
CN
China
Prior art keywords
chlorin
reaction mixture
formula
salt
anhydride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2007800274940A
Other languages
English (en)
Chinese (zh)
Other versions
CN101490057A (zh
Inventor
L·徐
A·J·帕伦伯格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Light Sciences Oncology Inc
Original Assignee
Light Sciences Oncology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Light Sciences Oncology Inc filed Critical Light Sciences Oncology Inc
Publication of CN101490057A publication Critical patent/CN101490057A/zh
Application granted granted Critical
Publication of CN101490057B publication Critical patent/CN101490057B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2007800274940A 2006-06-30 2007-06-29 制造光活性剂的组合物和方法 Expired - Fee Related CN101490057B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81776906P 2006-06-30 2006-06-30
US60/817,769 2006-06-30
PCT/US2007/015087 WO2008005308A2 (en) 2006-06-30 2007-06-29 Compositions and methods of making a chlorin e6 derivative as a photoactive agent

Publications (2)

Publication Number Publication Date
CN101490057A CN101490057A (zh) 2009-07-22
CN101490057B true CN101490057B (zh) 2013-02-27

Family

ID=38739490

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2007800274940A Expired - Fee Related CN101490057B (zh) 2006-06-30 2007-06-29 制造光活性剂的组合物和方法

Country Status (10)

Country Link
US (3) US8198312B2 (enExample)
EP (1) EP2057169A2 (enExample)
JP (1) JP5323693B2 (enExample)
KR (1) KR101456839B1 (enExample)
CN (1) CN101490057B (enExample)
AU (1) AU2007269784B2 (enExample)
CA (1) CA2655723C (enExample)
RU (1) RU2009102973A (enExample)
SG (1) SG172733A1 (enExample)
WO (1) WO2008005308A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2885311Y (zh) 2006-01-18 2007-04-04 郑成福 经尿道光动力疗法前列腺治疗仪
US7465312B2 (en) 2006-05-02 2008-12-16 Green Medical, Inc. Systems and methods for treating superficial venous malformations like spider veins
WO2007130465A2 (en) * 2006-05-02 2007-11-15 Green Medical, Inc. Systems and methods for treating superficial venous malformations like spider veins
JP5323693B2 (ja) 2006-06-30 2013-10-23 ライト、サイエンシーズ、オンコロジー、インコーポレイテッド 光活性剤としてのクロリンｅ６誘導体の組成物およびクロリンｅ６誘導体を製造する方法
CN103030644B (zh) * 2011-09-30 2015-01-14 齐鲁制药有限公司 一种他拉泊芬及其中间体的制备方法
US10740438B2 (en) 2012-08-16 2020-08-11 Ginger.io, Inc. Method and system for characterizing and/or treating poor sleep behavior
CN109785972B (zh) 2012-08-16 2023-09-26 橙点公司 用于对行为和健康变化进行建模的方法
US10741285B2 (en) 2012-08-16 2020-08-11 Ginger.io, Inc. Method and system for providing automated conversations
US10650920B2 (en) 2012-08-16 2020-05-12 Ginger.io, Inc. Method and system for improving care determination
US10748645B2 (en) 2012-08-16 2020-08-18 Ginger.io, Inc. Method for providing patient indications to an entity
US10276260B2 (en) 2012-08-16 2019-04-30 Ginger.io, Inc. Method for providing therapy to an individual
RU2523380C1 (ru) * 2013-05-21 2014-07-20 Общество с ограниченной ответственностью "ГЕЛИОХЛОРИН" Фотосенсибилизатор и способ его получения

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675338A (en) * 1984-07-18 1987-06-23 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US4693885A (en) 1984-07-18 1987-09-15 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US4977177A (en) * 1985-04-30 1990-12-11 Nippon Petrochemicals Company, Ltd. Tetrapyrrole polyaminomonocarboxylic acid therapeutic agents
US4656186A (en) 1985-04-30 1987-04-07 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
JP3565442B2 (ja) * 1993-04-22 2004-09-15 新日本石油化学株式会社 哺乳類の関節炎の診断剤および／または治療剤
JP5323693B2 (ja) 2006-06-30 2013-10-23 ライト、サイエンシーズ、オンコロジー、インコーポレイテッド 光活性剤としてのクロリンｅ６誘導体の組成物およびクロリンｅ６誘導体を製造する方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Naturally-derived porphyrinand chlorine photosensitizersfor photodynamic therapy;Hargus,J.A.;《A Thesis Submitted to the Graduate Faculty of theLouisiana State University andAgricultural and Mechanical Collegein partial fulfillment of therequirements for the degree of Master of Science》;20051231;第44-45页 *

Also Published As

Publication number Publication date
US20080021210A1 (en) 2008-01-24
CA2655723A1 (en) 2008-01-10
WO2008005308A3 (en) 2008-03-06
JP5323693B2 (ja) 2013-10-23
JP2009542672A (ja) 2009-12-03
AU2007269784A1 (en) 2008-01-10
US8198312B2 (en) 2012-06-12
US8063203B2 (en) 2011-11-22
US20130281689A1 (en) 2013-10-24
RU2009102973A (ru) 2010-08-10
WO2008005308A2 (en) 2008-01-10
KR20090033463A (ko) 2009-04-03
US8822677B2 (en) 2014-09-02
KR101456839B1 (ko) 2014-11-03
SG172733A1 (en) 2011-07-28
US20110105745A1 (en) 2011-05-05
CN101490057A (zh) 2009-07-22
AU2007269784B2 (en) 2012-07-05
EP2057169A2 (en) 2009-05-13
CA2655723C (en) 2014-11-18

Similar Documents

Publication Publication Date Title
CN101490057B (zh) 制造光活性剂的组合物和方法
KR102634720B1 (ko) 벤조디아제핀-2-온 및 벤조아제핀-2-온 유도체의 분할 방법
JP2009542672A5 (enExample)
US12173011B2 (en) Compounds and methods of their manufacturing
CN114539343A (zh) 一种甘氨胆酸的制备方法
CN112047888A (zh) 一种合成恩杂鲁胺的方法
CN111315722A (zh) 制备月桂酰阿立哌唑的方法
WO2015011609A1 (en) Process for the preparation of linagliptin and an intermediate thereof
CN104093718B (zh) 用于2-苯基-[1,2,4]三唑并[1,5-a]吡啶衍生物的制备的方法
RU2182151C2 (ru) Способ ацилирования гексакис(фенилметил)гексаазаизовюрцитана
RU2776703C2 (ru) Способы разделения производных бензодиазепин-2-она и бензоазепин-2-она
CN115010617B (zh) 一种碘帕醇的制备方法
RU2490273C1 (ru) Способ получения метилфеофорбида (а)
CA2374639C (en) Process for the preparation of fumagillin
RU2245336C2 (ru) Способ получения 3-аминопроизводных рифамицина s
CN115785067A (zh) 一种艾司奥美拉唑硫醚的杂质化合物的制备方法
KR20160101372A (ko) 5-아미노레불린산 헥실 에스테르 하이드로클로라이드의 제조방법
BE844112A (fr) Nouveaux derives d'un antibiotique denomme xk-62-2 et leurs procede deproduction, et les compositions pharmaceutiques qui les contiennent
TR201616665A2 (tr) Antioksidan aktiviteye sahip 3-klorabenzaldehit içeren hidrazon türevinin üretimine ilişkin yöntem
JPWO1998055492A1 (ja) 抗真菌剤ｖ−２８−３ｍの製造方法
JP2019135220A (ja) Ｌ−カルノシン及びその誘導体の製造方法
HK1133001B (en) Novel method for producing 4,4'-(1-methyl-1,2-ethanediyl)-bis-(2,6-piperazinedione)
HK1133001A1 (en) Novel method for producing 4,4'-(1-methyl-1,2-ethanediyl)-bis-(2,6-piperazinedione)

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: EUROCELTIQUE S.A.

Free format text: FORMER OWNER: LIGHT SCIENCES ONCOLOGY INC.

Effective date: 20141021

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20141021

Address after: Luxemburg Luxemburg

Patentee after: EURO-CELTIQUE S.A.

Address before: Washington, USA

Patentee before: LIGHT SCIENCES ONCOLOGY, Inc.

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20230911

Address after: Washington, DC

Patentee after: LIGHT SCIENCES ONCOLOGY, Inc.

Address before: Luxemburg Luxemburg

Patentee before: EURO-CELTIQUE S.A.

CP02 Change in the address of a patent holder
CP02 Change in the address of a patent holder

Address after: Ore

Patentee after: LIGHT SCIENCES ONCOLOGY, Inc.

Address before: Washington, DC

Patentee before: LIGHT SCIENCES ONCOLOGY, Inc.

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130227