CN101422450B - 一种具有降血糖和减肥作用的菧类天然药物 - Google Patents
一种具有降血糖和减肥作用的菧类天然药物 Download PDFInfo
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- CN101422450B CN101422450B CN2008101990126A CN200810199012A CN101422450B CN 101422450 B CN101422450 B CN 101422450B CN 2008101990126 A CN2008101990126 A CN 2008101990126A CN 200810199012 A CN200810199012 A CN 200810199012A CN 101422450 B CN101422450 B CN 101422450B
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A—HUMAN NECESSITIES
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- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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Abstract
Description
化合物 | IC50(μM) |
2 | 28 |
1 | 58 |
3 | 125 |
树豆酮酸A | 4.5 |
Molybdate* | 25 |
RK-682* | 54 |
Claims (4)
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CN2008101990126A CN101422450B (zh) | 2008-10-09 | 2008-10-09 | 一种具有降血糖和减肥作用的菧类天然药物 |
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CN101422450A CN101422450A (zh) | 2009-05-06 |
CN101422450B true CN101422450B (zh) | 2011-11-09 |
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CN109105894A (zh) * | 2017-06-22 | 2019-01-01 | 宋祖莹 | 树豆萃取方法及其应用 |
Families Citing this family (10)
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CN104470514A (zh) * | 2011-07-28 | 2015-03-25 | 广州市允中投资发展有限公司 | 具有菧类化合物结构的降血糖和减肥药物 |
CN102670576B (zh) * | 2012-04-20 | 2014-04-02 | 广州允中生物科技有限公司 | 树豆酮酸a在制备糖尿病伴随症及高脂血症药物中的应用 |
CN103351285B (zh) * | 2013-06-27 | 2015-05-06 | 广州中医药大学热带医学研究所 | 菧类化合物及其在制备骨质疏松症及高脂血症药物中应用 |
CN103356607B (zh) * | 2013-06-27 | 2015-01-14 | 广州中医药大学热带医学研究所 | 树豆内酯a在制备治疗骨质疏松症药物中的应用 |
CN103804187B (zh) * | 2014-01-23 | 2015-04-22 | 苏州美诺医药科技有限公司 | 一种菧类化合物树豆酮酸a的合成方法 |
CN103772189B (zh) * | 2014-01-23 | 2015-05-27 | 苏州美诺医药科技有限公司 | 一种菧类化合物甲基树豆酮酸a的合成方法 |
CN106309419B (zh) * | 2015-06-19 | 2019-09-10 | 广州允中生物科技有限公司 | 树豆酮酸a及其类似物在制备治疗骨质疏松症药物中的应用 |
CN110563690A (zh) * | 2016-05-13 | 2019-12-13 | 贵州医科大学 | 树豆酮酸a结构类似物、其组合物及其在药物中的应用 |
CN106117156B (zh) * | 2016-06-14 | 2019-12-17 | 南通大学 | 一种含5-苯基异噁唑类菧基团的化合物及其制备方法 |
JP7198805B2 (ja) | 2017-09-15 | 2023-01-04 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 神経疾患の予防及び治療に使用するためのメロテルペノイド化合物 |
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