CN103804187B - 一种菧类化合物树豆酮酸a的合成方法 - Google Patents
一种菧类化合物树豆酮酸a的合成方法 Download PDFInfo
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- CN103804187B CN103804187B CN201410033051.4A CN201410033051A CN103804187B CN 103804187 B CN103804187 B CN 103804187B CN 201410033051 A CN201410033051 A CN 201410033051A CN 103804187 B CN103804187 B CN 103804187B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
- C07C51/31—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation of cyclic compounds with ring-splitting
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
- C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201410033051.4A CN103804187B (zh) | 2014-01-23 | 2014-01-23 | 一种菧类化合物树豆酮酸a的合成方法 |
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CN201410033051.4A CN103804187B (zh) | 2014-01-23 | 2014-01-23 | 一种菧类化合物树豆酮酸a的合成方法 |
Publications (2)
Publication Number | Publication Date |
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CN103804187A CN103804187A (zh) | 2014-05-21 |
CN103804187B true CN103804187B (zh) | 2015-04-22 |
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CN201410033051.4A Active CN103804187B (zh) | 2014-01-23 | 2014-01-23 | 一种菧类化合物树豆酮酸a的合成方法 |
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Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106854141A (zh) * | 2015-12-08 | 2017-06-16 | 湖南华腾制药有限公司 | 一种4-氯甲苯化合物的合成方法 |
CN106397207B (zh) * | 2016-05-13 | 2020-12-08 | 贵州医科大学 | 树豆酮酸a结构类似物、其组合物及其在药物中的应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101422450A (zh) * | 2008-10-09 | 2009-05-06 | 广州市允中投资发展有限公司 | 一种具有降血糖和减肥作用的菧类天然药物 |
CN103351285A (zh) * | 2013-06-27 | 2013-10-16 | 广州中医药大学热带医学研究所 | 菧类化合物及其在制备骨质疏松症及高脂血症药物中应用 |
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2014
- 2014-01-23 CN CN201410033051.4A patent/CN103804187B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101422450A (zh) * | 2008-10-09 | 2009-05-06 | 广州市允中投资发展有限公司 | 一种具有降血糖和减肥作用的菧类天然药物 |
CN103351285A (zh) * | 2013-06-27 | 2013-10-16 | 广州中医药大学热带医学研究所 | 菧类化合物及其在制备骨质疏松症及高脂血症药物中应用 |
Non-Patent Citations (1)
Title |
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Synthesis of the Lichen Depsides Miriquidic Acid and Normiriquidic Acid;John A.EIix et al.;《Aust.J.Chem.》;19861231;第39卷;791-797 * |
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Effective date of registration: 20210420 Address after: No. 360, Kaiyuan Avenue, Changshan Town, Zouping, Binzhou City, Shandong Province Patentee after: Shandong Ruihua Pharmaceutical Co.,Ltd. Address before: Suzhou City, Jiangsu Province, Suzhou Industrial Park 215125 Xinghu Street No. 218 biological nano science and Technology Park building C9 Room 501 Patentee before: SUZHOU MEDINOAH Co.,Ltd. |
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Address after: 256200 No. 360, Kaiyuan Avenue, Changshan Town, Zouping, Binzhou City, Shandong Province Patentee after: Shandong Ruihua Pharmaceutical Co.,Ltd. Address before: 256200 No. 360, Kaiyuan Avenue, Changshan Town, Zouping, Binzhou City, Shandong Province Patentee before: Shandong Ruihua Pharmaceutical Co.,Ltd. |
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Effective date of registration: 20220209 Address after: 256200 east of Yuehe 6th Road, Binzhou economic and Technological Development Zone, Shandong Province, middle of Huixian 3rd road and Huixian 4th Road Patentee after: Shandong longchen Pharmaceutical Co.,Ltd. Address before: 256200 No. 360, Kaiyuan Avenue, Changshan Town, Zouping, Binzhou City, Shandong Province Patentee before: Shandong Ruihua Pharmaceutical Co.,Ltd. |
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