CN101405594B - 荧光读取器 - Google Patents

荧光读取器 Download PDF

Info

Publication number
CN101405594B
CN101405594B CN2007800096888A CN200780009688A CN101405594B CN 101405594 B CN101405594 B CN 101405594B CN 2007800096888 A CN2007800096888 A CN 2007800096888A CN 200780009688 A CN200780009688 A CN 200780009688A CN 101405594 B CN101405594 B CN 101405594B
Authority
CN
China
Prior art keywords
substrate
fluorescence
fluorescence reader
light
reader according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2007800096888A
Other languages
English (en)
Chinese (zh)
Other versions
CN101405594A (zh
Inventor
托马斯·林斯特龙
伊布·曼德尔-哈特维格
奥韦·奥曼
约翰·巴克伦
肯尼特·维尔赫尔姆森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
J Remsen International Assets LLC
J&j Jsc
Original Assignee
Amic AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amic AB filed Critical Amic AB
Publication of CN101405594A publication Critical patent/CN101405594A/zh
Application granted granted Critical
Publication of CN101405594B publication Critical patent/CN101405594B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6465Angular discrimination

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN2007800096888A 2006-03-22 2007-03-21 荧光读取器 Expired - Fee Related CN101405594B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE06006423 2006-03-22
SE0600642-3 2006-03-22
SE0600642A SE529711C2 (sv) 2006-03-22 2006-03-22 Fluorescensläsare
PCT/SE2007/000275 WO2007108752A1 (en) 2006-03-22 2007-03-21 Fluorescence reader

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201210123087.2A Division CN102636469B (zh) 2006-03-22 2007-03-21 荧光读取器

Publications (2)

Publication Number Publication Date
CN101405594A CN101405594A (zh) 2009-04-08
CN101405594B true CN101405594B (zh) 2012-06-27

Family

ID=38522714

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2007800096888A Expired - Fee Related CN101405594B (zh) 2006-03-22 2007-03-21 荧光读取器
CN201210123087.2A Expired - Fee Related CN102636469B (zh) 2006-03-22 2007-03-21 荧光读取器

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201210123087.2A Expired - Fee Related CN102636469B (zh) 2006-03-22 2007-03-21 荧光读取器

Country Status (8)

Country Link
US (2) US8691153B2 (https=)
EP (1) EP1996922B1 (https=)
JP (1) JP5705432B2 (https=)
CN (2) CN101405594B (https=)
AU (1) AU2007227809B2 (https=)
BR (1) BRPI0709018A2 (https=)
SE (1) SE529711C2 (https=)
WO (1) WO2007108752A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102636469A (zh) * 2006-03-22 2012-08-15 阿米克公司 荧光读取器

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2832494C (en) 2011-04-06 2019-11-26 Ortho-Clinical Diagnostics, Inc. Assay device having rhombus-shaped projections
US8605283B2 (en) * 2011-05-05 2013-12-10 Emd Millipore Corporation Apparatus and method for increasing collection efficiency in capillary based flowcytometry
US9642568B2 (en) * 2011-09-06 2017-05-09 Medtronic Minimed, Inc. Orthogonally redundant sensor systems and methods
WO2013109821A1 (en) 2012-01-20 2013-07-25 Ortho-Clinical Diagnostics, Inc. Assay device having multiplexing
BR102013001395A2 (pt) 2012-01-20 2015-11-17 Ortho Clinical Diagnostics Inc dispositivo de ensaio tendo múltiplas células de reagentes
US20130210036A1 (en) 2012-01-20 2013-08-15 Ortho-Clinical Diagnostics, Inc. Controlling Fluid Flow Through An Assay Device
BR102013001324A2 (pt) 2012-01-20 2015-07-28 Ortho Clinical Diagnostics Inc Dispositivo de ensaio tendo tamanho de amostra controlável e método para controlar o tamanho da amostra em um dispositivo de ensaio
KR20130085991A (ko) 2012-01-20 2013-07-30 오르토-클리니칼 다이아그노스틱스, 인코포레이티드 코너 주위의 균일한 유동을 갖는 분석 장치
EP2888284B1 (en) 2012-08-21 2022-07-06 Janssen Pharmaceutica NV Antibodies to risperidone haptens and use thereof
JP2015529199A (ja) 2012-08-21 2015-10-05 オルソ−クリニカル ダイアグノスティクス,インコーポレイティド パリペリドンハプテンに対する抗体及びその使用
WO2014031656A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to olanzapine haptens and use thereof
JP6450314B2 (ja) 2012-08-21 2019-01-09 ヤンセン ファーマシューティカ エヌ.ベー. クエチアピンハプテンに対する抗体及びその使用
CA2882562C (en) 2012-08-21 2019-08-27 Eric Hryhorenko Antibodies to aripiprazole and use thereof
ES2691092T3 (es) 2012-08-21 2018-11-23 Janssen Pharmaceutica Nv Anticuerpos contra la risperidona y uso de los mismos
JP6131414B2 (ja) 2012-08-21 2017-05-24 ヤンセン ファーマシューティカ エヌ.ベー. アリピプラゾールのハプテン及びイムノアッセイにおけるそれらの使用
PL2888592T3 (pl) 2012-08-21 2018-03-30 Janssen Pharmaceutica Nv Przeciwciała względem kwetiapiny i ich zastosowania
JP6389176B2 (ja) 2012-08-21 2018-09-12 ヤンセン ファーマシューティカ エヌ.ベー. アリピプラゾールハプテンに対する抗体及びその使用
JP2015527365A (ja) 2012-08-21 2015-09-17 オルソ−クリニカル ダイアグノスティクス,インコーポレイティド パリペリドンに対する抗体及びその使用
CA2882596C (en) 2012-08-21 2019-05-14 Ortho-Clinical Diagnostics, Inc. Antibodies to olanzapine and use thereof
JP6359263B2 (ja) 2012-11-15 2018-07-18 オーソ・クリニカル・ダイアグノスティックス・インコーポレーテッド 流れモニタリングに基づく、側方流動アッセイ装置の品質/プロセス制御
JP6328655B2 (ja) 2012-11-15 2018-05-23 オーソ・クリニカル・ダイアグノスティックス・インコーポレーテッド 反応時間を使用してアッセイを較正すること
CA2841692C (en) 2013-02-12 2023-08-22 Zhong Ding Reagent zone deposition pattern
FI128503B (en) * 2013-02-27 2020-06-30 Teknologian Tutkimuskeskus Vtt Oy Sample plate and assay procedure
EP2777499B1 (en) 2013-03-15 2015-09-16 Ortho-Clinical Diagnostics Inc Rotatable fluid sample collection device
EP2778679B1 (en) 2013-03-15 2017-09-27 Ortho-Clinical Diagnostics, Inc. Rotable disk-shaped fluid sample collection device
EP3077806B1 (en) 2013-12-06 2019-09-11 Ortho Clinical Diagnostics, Inc. Assay device having a wash port
US9903858B2 (en) 2014-07-23 2018-02-27 Ortho-Clinical Diagnostics, Inc. Multiplexing with single sample metering event to increase throughput
US10071373B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device having flow constrictions
US11033896B2 (en) 2014-08-08 2021-06-15 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device with filtration flow control
KR101621050B1 (ko) * 2014-10-23 2016-05-13 주식회사 이뮨메드 의료용 진단 키트의 형광리더기
EP3298403A1 (en) 2015-05-19 2018-03-28 Ortho-Clinical Diagnostics Inc Method of improving liquid sample flow in assay device
EP3390449A1 (en) 2015-12-17 2018-10-24 Janssen Pharmaceutica N.V. Antibodies to risperidone and use thereof
US10435478B2 (en) 2015-12-17 2019-10-08 Janssen Pharmaceutica Nv Antibodies to quetiapine and use thereof
CN107242860B (zh) * 2017-07-25 2021-01-19 京东方科技集团股份有限公司 荧光分子层析成像系统及方法
EP3460456B1 (en) * 2017-09-20 2020-08-26 IMEC vzw A biosensor system for detecting supercritical angle fluorescent light
JP7106217B2 (ja) * 2018-08-22 2022-07-26 株式会社ディスコ ファセット領域の検出方法及び検出装置
JP2022523799A (ja) * 2019-03-01 2022-04-26 ヴィディア・ホールディングス・リミテッド 光学要素における、または関連した改善
EP3705875B1 (en) 2019-03-05 2022-11-30 IMEC vzw An apparatus and method for detecting photoluminescent light emitted from a sample

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5344784A (en) * 1988-11-29 1994-09-06 Applied Research Systems Ars Holding N.V. Fluorescent assay and sensor therefor

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB965084A (en) * 1959-04-17 1964-07-29 Lumalampan Ab Improvements in or relating to an electroluminescent device
US3593055A (en) * 1969-04-16 1971-07-13 Bell Telephone Labor Inc Electro-luminescent device
US3973129A (en) * 1975-01-10 1976-08-03 Bell Telephone Laboratories, Incorporated Fluorimetric apparatus and method for analysis of body fluid
WO1983001112A1 (en) * 1981-09-18 1983-03-31 Carter, Timothy Method for the determination of species in solution with an optical wave-guide
US4956150A (en) * 1985-11-27 1990-09-11 Alerchek Disposable microtiter stick
US5158720A (en) * 1985-12-09 1992-10-27 Mcdonnell Douglas Corporation Method and system for continuous in situ monitoring of viscosity
CA1321488C (en) 1987-08-22 1993-08-24 Martin Francis Finlan Biological sensors
US6767510B1 (en) 1992-05-21 2004-07-27 Biosite, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6019944A (en) * 1992-05-21 2000-02-01 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6156270A (en) 1992-05-21 2000-12-05 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6905882B2 (en) 1992-05-21 2005-06-14 Biosite, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6143576A (en) 1992-05-21 2000-11-07 Biosite Diagnostics, Inc. Non-porous diagnostic devices for the controlled movement of reagents
JP3326708B2 (ja) 1993-08-31 2002-09-24 日水製薬株式会社 光学的測定装置およびその方法
JPH07199236A (ja) * 1993-12-28 1995-08-04 Fujitsu Ltd 光スイッチ及び光分配器
US5399499A (en) * 1994-05-13 1995-03-21 Eastman Kodak Company Method of using multiwavelength upconversion for sample element interrogation in medical diagnostic equipment
JPH07318481A (ja) * 1994-05-25 1995-12-08 Daikin Ind Ltd 光学的測定方法およびその装置
MXPA96005828A (es) * 1994-05-27 2005-07-15 Novartis Ag Tambien Denominada Proceso para detectar luminescencia excitada evanescentemente.
EP0736767A1 (de) * 1995-04-07 1996-10-09 Ciba-Geigy Ag Optische Detektionsvorrichtung für analytische Messungen an chemischen Substanzen
AU4379197A (en) * 1996-08-16 1998-03-06 Novartis Ag Optical detector
US6391265B1 (en) 1996-08-26 2002-05-21 Biosite Diagnostics, Inc. Devices incorporating filters for filtering fluid samples
EP1443320A3 (de) * 1997-09-10 2005-02-02 Artificial Sensing Instruments ASI AG Sensorchip zur Charakterisierung einer chemischen und/oder biochemischen Substanz
DE59915078D1 (https=) * 1998-02-05 2009-10-22 Novartis Ag
DE19810615A1 (de) 1998-03-12 1999-09-16 Thomas Ruckstuhl Optische Anordnung zum Erfassen von Licht
CN100385232C (zh) * 1998-08-26 2008-04-30 医药及科学传感器公司 基于光学的感测装置
EP1983331B1 (en) * 1999-05-28 2011-07-13 Yokogawa Electric Corporation Optical system for reading a biochip
JP5006494B2 (ja) * 1999-08-13 2012-08-22 バイエル・テクノロジー・サービシーズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 複数の分析物を測定するためのデバイス及び方法
HK1048709A1 (zh) * 1999-12-03 2003-04-11 Cree, Inc. 透过使用内置及外置光元件提高发光二极管(led)中的抽光效果
AU2001231290A1 (en) 2000-02-03 2001-08-14 Alpha Innotech Corporation Improved microarray reader
US20020093654A1 (en) * 2000-07-11 2002-07-18 Lieberman Robert A. Apparatus and method for imaging
US6905816B2 (en) * 2000-11-27 2005-06-14 Intelligent Medical Devices, Inc. Clinically intelligent diagnostic devices and methods
US20040126767A1 (en) 2002-12-27 2004-07-01 Biosite Incorporated Method and system for disease detection using marker combinations
WO2003060446A1 (en) 2002-01-12 2003-07-24 Maven Technologies, Llc Apparatus and method for imaging
KR20030064298A (ko) * 2002-01-23 2003-07-31 가부시키가이샤 히다치 고쿠사이 덴키 형광체 검사 방법 및 형광체 검사 장치
US6867420B2 (en) * 2002-06-03 2005-03-15 The Regents Of The University Of California Solid-state detector and optical system for microchip analyzers
JP4193421B2 (ja) * 2002-06-06 2008-12-10 ソニー株式会社 バイオアッセイ装置及びその製造方法、並びにバイオアッセイ方法
SE0201738D0 (sv) 2002-06-07 2002-06-07 Aamic Ab Micro-fluid structures
JP4480130B2 (ja) * 2003-12-16 2010-06-16 キヤノン株式会社 光学分析装置
KR100568298B1 (ko) * 2004-03-30 2006-04-05 삼성전기주식회사 외부양자효율이 개선된 질화물 반도체 및 그 제조방법
SE529711C2 (sv) * 2006-03-22 2007-11-06 Aamic Ab Fluorescensläsare

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5344784A (en) * 1988-11-29 1994-09-06 Applied Research Systems Ars Holding N.V. Fluorescent assay and sensor therefor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102636469A (zh) * 2006-03-22 2012-08-15 阿米克公司 荧光读取器

Also Published As

Publication number Publication date
CN102636469A (zh) 2012-08-15
JP2009530637A (ja) 2009-08-27
AU2007227809B2 (en) 2012-10-04
EP1996922A1 (en) 2008-12-03
WO2007108752A1 (en) 2007-09-27
US8691153B2 (en) 2014-04-08
EP1996922B1 (en) 2018-11-21
US9279768B2 (en) 2016-03-08
US20140212984A1 (en) 2014-07-31
CN102636469B (zh) 2016-07-06
EP1996922A4 (en) 2012-10-24
JP5705432B2 (ja) 2015-04-22
SE0600642L (sv) 2007-09-23
US20070231883A1 (en) 2007-10-04
AU2007227809A1 (en) 2007-09-27
SE529711C2 (sv) 2007-11-06
CN101405594A (zh) 2009-04-08
BRPI0709018A2 (pt) 2011-06-21

Similar Documents

Publication Publication Date Title
CN101405594B (zh) 荧光读取器
EP1912740B1 (en) Optical assay system
JP5824038B2 (ja) ルミネセンスベースセンサシステム
US6714297B1 (en) Light detecting optical device
US20100136709A1 (en) Receptacle and method for the detection of fluorescence
KR20090064917A (ko) 표면 플라즈몬 공명을 이용한 형광현미경
CN100338445C (zh) 光学部件、使用该部件的光检测装置和方法、及分析方法
US20190178799A1 (en) Biochip device
US7750316B2 (en) Polymer biochip for detecting fluorescence
US8119995B2 (en) Device for detection of excitation using a multiple spot arrangement
CN111788473B (zh) 用于检测结合亲和力的装置
CA2685574A1 (en) Receptacle and method for the detection of fluorescence
HK40037086B (zh) 用於检测结合亲和力的装置

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20180626

Address after: Delaware

Patentee after: J Remsen international assets LLC

Address before: Solna, Sweden

Patentee before: J&J JSC

Effective date of registration: 20180626

Address after: Solna, Sweden

Patentee after: J&J JSC

Address before: Uppsala, Sweden

Patentee before: Amic AB

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120627