CN101397336A - 奈瑟球菌的抗原性肽 - Google Patents
奈瑟球菌的抗原性肽 Download PDFInfo
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- CN101397336A CN101397336A CNA2008100999833A CN200810099983A CN101397336A CN 101397336 A CN101397336 A CN 101397336A CN A2008100999833 A CNA2008100999833 A CN A2008100999833A CN 200810099983 A CN200810099983 A CN 200810099983A CN 101397336 A CN101397336 A CN 101397336A
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- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
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- 238000010361 transduction Methods 0.000 description 1
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- 229940035722 triiodothyronine Drugs 0.000 description 1
- 101150035767 trp gene Proteins 0.000 description 1
- 101150044170 trpE gene Proteins 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- ZHSGGJXRNHWHRS-VIDYELAYSA-N tunicamycin Chemical compound O([C@H]1[C@@H]([C@H]([C@@H](O)[C@@H](CC(O)[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C(NC(=O)C=C2)=O)O)O1)O)NC(=O)/C=C/CC(C)C)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O ZHSGGJXRNHWHRS-VIDYELAYSA-N 0.000 description 1
- MEYZYGMYMLNUHJ-UHFFFAOYSA-N tunicamycin Natural products CC(C)CCCCCCCCCC=CC(=O)NC1C(O)C(O)C(CC(O)C2OC(C(O)C2O)N3C=CC(=O)NC3=O)OC1OC4OC(CO)C(O)C(O)C4NC(=O)C MEYZYGMYMLNUHJ-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
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| GBGB9911683.2A GB9911683D0 (en) | 1999-05-19 | 1999-05-19 | Antigenic peptides |
| GB9911683.2 | 1999-05-19 |
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| CNA008106029A Division CN1671844A (zh) | 1999-05-19 | 2000-05-19 | 奈瑟球菌的抗原性肽 |
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| CNA2008100999833A Pending CN101397336A (zh) | 1999-05-19 | 2000-05-19 | 奈瑟球菌的抗原性肽 |
| CNA008106029A Pending CN1671844A (zh) | 1999-05-19 | 2000-05-19 | 奈瑟球菌的抗原性肽 |
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| CNA008106029A Pending CN1671844A (zh) | 1999-05-19 | 2000-05-19 | 奈瑟球菌的抗原性肽 |
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| AT (1) | ATE366313T1 (https=) |
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| BR (1) | BR0010720A (https=) |
| CA (1) | CA2374550A1 (https=) |
| CY (1) | CY1106875T1 (https=) |
| DE (1) | DE60035419T2 (https=) |
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| ES (1) | ES2288477T3 (https=) |
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| PT (1) | PT1194560E (https=) |
| RU (1) | RU2284332C2 (https=) |
| WO (1) | WO2000071574A2 (https=) |
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| EP2298900A1 (en) | 1996-09-17 | 2011-03-23 | Novartis Vaccines and Diagnostics, Inc. | Compositions and methods for treating intracellular diseases |
| WO2000066741A2 (en) | 1999-04-30 | 2000-11-09 | Chiron S.P.A. | Conserved neisserial antigens |
| NZ515935A (en) | 1999-05-19 | 2004-01-30 | Chiron S | Combination Neisserial compositions and vaccines for the prevention of infections due to Neisseria bacteria such as meningococcal meningitis |
| NZ521531A (en) * | 2000-02-28 | 2005-12-23 | Chiron S | Heterologous expression of neisserial proteins |
| US7094882B2 (en) | 2000-04-21 | 2006-08-22 | Yeda Research And Development Co. Ltd. | Growth factor which acts through erb b-4 rtk |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| ATE469915T1 (de) | 2001-07-27 | 2010-06-15 | Novartis Vaccines & Diagnostic | Antikörper gegen das meningokokken adhäsin app |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| US20060057160A1 (en) * | 2002-08-02 | 2006-03-16 | Ralph Biemans | Vaccine composition |
| HUE031886T2 (en) | 2002-10-11 | 2017-08-28 | Glaxosmithkline Biologicals Sa | Polypeptide vaccines for extensive protection against hypervirulent meningococcal lines |
| CU23237A1 (es) * | 2003-12-03 | 2007-09-26 | Ct Ingenieria Genetica Biotech | PROTEINA NMB1125 Y SU USO EN FORMULACIONES FARMACéUTICAS |
| CU23236A1 (es) * | 2003-12-03 | 2007-09-26 | Ct Ingenieria Genetica Biotech | PROTEINA NMB0928 Y SU USO EN FORMULACIONES FARMACéUTICAS P |
| RU2408605C2 (ru) | 2005-02-18 | 2011-01-10 | Анджиокем Инк. | Полипептид, способный преодолевать гематоэнцефалический барьер, и его конъюгат |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
| CA2740316A1 (en) | 2008-10-15 | 2010-04-22 | Angiochem Inc. | Conjugates of glp-1 agonists and uses thereof |
| CA2745524C (en) | 2008-12-05 | 2020-06-09 | Angiochem Inc. | Conjugates of neurotensin or neurotensin analogs and uses thereof |
| MX2011011023A (es) | 2009-04-20 | 2012-01-20 | Angiochem Inc | Tratamiento de cancer de ovarios usando un agente anti-cancer conjugado con un analogo de angiopep-2. |
| RU2012103240A (ru) | 2009-07-02 | 2013-08-10 | Ангиокем Инк. | Мультимерные пептидные конъюгаты и их применение |
| KR101061017B1 (ko) * | 2009-10-23 | 2011-08-31 | (주) 수파드엘릭사 | 암세포의 성장 및/또는 전이 억제용 약학 조성물 |
| JP2013530993A (ja) * | 2010-07-02 | 2013-08-01 | アンジオケム インコーポレーテッド | 治療用コンジュゲートのための短く且つｄ−アミノ酸を含有するポリペプチドおよびその使用 |
| CN107913396B (zh) | 2010-08-23 | 2022-03-08 | 惠氏有限责任公司 | 脑膜炎萘瑟氏菌rLP2086抗原的稳定制剂 |
| AU2011300409B2 (en) | 2010-09-10 | 2015-03-26 | Wyeth Llc | Non-lipidated variants of Neisseria meningitidis ORF2086 antigens |
| MY198910A (en) | 2012-03-09 | 2023-10-02 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| WO2014136064A2 (en) | 2013-03-08 | 2014-09-12 | Pfizer Inc. | Immunogenic fusion polypeptides |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| WO2016132294A1 (en) | 2015-02-19 | 2016-08-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| EP3307326B9 (en) | 2015-06-15 | 2021-02-24 | Angiochem Inc. | Methods for the treatment of leptomeningeal carcinomatosis |
| AU2018215585B2 (en) | 2017-01-31 | 2022-03-17 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| WO2021059181A1 (en) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
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-
1999
- 1999-05-19 GB GBGB9911683.2A patent/GB9911683D0/en not_active Ceased
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2000
- 2000-05-19 BR BR0010720-4A patent/BR0010720A/pt not_active IP Right Cessation
- 2000-05-19 EP EP06076711A patent/EP1767641A1/en not_active Withdrawn
- 2000-05-19 ES ES00931512T patent/ES2288477T3/es not_active Expired - Lifetime
- 2000-05-19 EP EP10075328A patent/EP2251424A1/en not_active Withdrawn
- 2000-05-19 NZ NZ515936A patent/NZ515936A/xx not_active IP Right Cessation
- 2000-05-19 CN CNA2008100999833A patent/CN101397336A/zh active Pending
- 2000-05-19 PT PT00931512T patent/PT1194560E/pt unknown
- 2000-05-19 MX MXPA01011833A patent/MXPA01011833A/es active IP Right Grant
- 2000-05-19 AU AU49460/00A patent/AU775972B2/en not_active Ceased
- 2000-05-19 CA CA002374550A patent/CA2374550A1/en not_active Abandoned
- 2000-05-19 DK DK00931512T patent/DK1194560T3/da active
- 2000-05-19 AT AT00931512T patent/ATE366313T1/de not_active IP Right Cessation
- 2000-05-19 CN CNA008106029A patent/CN1671844A/zh active Pending
- 2000-05-19 WO PCT/IB2000/000831 patent/WO2000071574A2/en not_active Ceased
- 2000-05-19 RU RU2001134170/13A patent/RU2284332C2/ru not_active IP Right Cessation
- 2000-05-19 JP JP2000619829A patent/JP2003500040A/ja active Pending
- 2000-05-19 EP EP00931512A patent/EP1194560B1/en not_active Revoked
- 2000-05-19 DE DE60035419T patent/DE60035419T2/de not_active Revoked
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2004
- 2004-11-17 AU AU2004231178A patent/AU2004231178A1/en not_active Abandoned
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2005
- 2005-04-13 US US11/105,309 patent/US20070053926A1/en not_active Abandoned
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2007
- 2007-09-17 CY CY20071101199T patent/CY1106875T1/el unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| MXPA01011833A (es) | 2002-05-06 |
| JP2011015684A (ja) | 2011-01-27 |
| EP1767641A1 (en) | 2007-03-28 |
| BR0010720A (pt) | 2002-06-11 |
| ES2288477T3 (es) | 2008-01-16 |
| EP1194560A2 (en) | 2002-04-10 |
| ATE366313T1 (de) | 2007-07-15 |
| DE60035419D1 (de) | 2007-08-16 |
| JP2003500040A (ja) | 2003-01-07 |
| AU4946000A (en) | 2000-12-12 |
| US20070053926A1 (en) | 2007-03-08 |
| CA2374550A1 (en) | 2000-11-30 |
| WO2000071574A3 (en) | 2002-01-24 |
| RU2284332C2 (ru) | 2006-09-27 |
| DE60035419T2 (de) | 2008-02-28 |
| CN1671844A (zh) | 2005-09-21 |
| EP2251424A1 (en) | 2010-11-17 |
| CY1106875T1 (el) | 2012-09-26 |
| DK1194560T3 (da) | 2007-11-05 |
| GB9911683D0 (en) | 1999-07-21 |
| WO2000071574A2 (en) | 2000-11-30 |
| PT1194560E (pt) | 2007-10-17 |
| AU2004231178A1 (en) | 2004-12-23 |
| EP1194560B1 (en) | 2007-07-04 |
| NZ515936A (en) | 2004-12-24 |
| AU775972B2 (en) | 2004-08-19 |
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