CN101241078A - Serrs活性微粒 - Google Patents

Serrs活性微粒 Download PDF

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Publication number
CN101241078A
CN101241078A CNA2008100823662A CN200810082366A CN101241078A CN 101241078 A CN101241078 A CN 101241078A CN A2008100823662 A CNA2008100823662 A CN A2008100823662A CN 200810082366 A CN200810082366 A CN 200810082366A CN 101241078 A CN101241078 A CN 101241078A
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CN
China
Prior art keywords
serrs
beads
active
dye
target molecule
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Pending
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CNA2008100823662A
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English (en)
Chinese (zh)
Inventor
W·E·史密斯
D·格雷厄姆
P·科马克
A·麦凯布
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University of Strathclyde
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University of Strathclyde
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Publication of CN101241078A publication Critical patent/CN101241078A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B20/00—Methods specially adapted for identifying library members
    • C40B20/04—Identifying library members by means of a tag, label, or other readable or detectable entity associated with the library members, e.g. decoding processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CNA2008100823662A 2002-07-12 2003-07-11 Serrs活性微粒 Pending CN101241078A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0216197.4 2002-07-12
GBGB0216197.4A GB0216197D0 (en) 2002-07-12 2002-07-12 Serrs active particles

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB038166070A Division CN100413977C (zh) 2002-07-12 2003-07-11 Serrs活性微粒

Publications (1)

Publication Number Publication Date
CN101241078A true CN101241078A (zh) 2008-08-13

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Family Applications (2)

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CNA2008100823662A Pending CN101241078A (zh) 2002-07-12 2003-07-11 Serrs活性微粒
CNB038166070A Expired - Fee Related CN100413977C (zh) 2002-07-12 2003-07-11 Serrs活性微粒

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNB038166070A Expired - Fee Related CN100413977C (zh) 2002-07-12 2003-07-11 Serrs活性微粒

Country Status (8)

Country Link
US (1) US20050130163A1 (enExample)
EP (1) EP1521846B1 (enExample)
JP (1) JP4754213B2 (enExample)
CN (2) CN101241078A (enExample)
AU (1) AU2003281070B2 (enExample)
CA (1) CA2492213C (enExample)
GB (1) GB0216197D0 (enExample)
WO (1) WO2004007767A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102265155A (zh) * 2008-11-10 2011-11-30 卢米耐克斯公司 用于制备和使用多重检测中的大孔珠粒的方法和体系
CN102323412A (zh) * 2011-08-09 2012-01-18 中国科学院合肥物质科学研究院 一种拉曼编码微球的用途及利用拉曼编码微球检测肿瘤标志物的方法
CN102811943A (zh) * 2009-12-11 2012-12-05 韩国化学研究院 拉曼活性分子位于纳米粒子二聚体的结合部的二聚体核壳纳米粒子、其用途及制备方法
CN109342392A (zh) * 2018-11-09 2019-02-15 中国科学院烟台海岸带研究所 一种以聚苯乙烯为包裹壳层材料的表面增强拉曼散射纳米探针及其制备方法

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US20070048797A1 (en) * 2004-08-11 2007-03-01 Xing Su Composite organic inorganic nanoclusters as carriers and identifiers of tester molecules
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JP6099108B2 (ja) 2013-05-30 2017-03-29 公立大学法人大阪府立大学 被検出物質の検出装置および方法
CN104975279B (zh) * 2015-07-22 2018-04-20 中国工程物理研究院材料研究所 一种制备表面增强拉曼基底的溶胶及方法
CN106947018B (zh) * 2017-03-09 2019-02-05 江苏大学 一种高性能和高度可控的核壳型印迹传感器及制备方法和用途
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CN110161243B (zh) * 2018-02-13 2021-05-04 北京化工大学 一种用于活细胞内肿瘤标志物实时成像的纳米人工抗体抑制剂及其制备方法
CN109342387B (zh) * 2018-10-19 2021-08-24 福建省林业科学研究院 一种基于纳米银胶表面拉曼增强检测酮康唑的方法
CN109307697B (zh) * 2018-11-05 2021-02-23 济南大学 一种检测吡喹酮的电致化学发光传感电极的制备方法及应用
CN109540867B (zh) * 2018-11-30 2021-07-27 东南大学 一种基于分子印迹纳米纤维膜的塑化剂拉曼光谱检测方法
CN110376179B (zh) * 2019-07-25 2022-03-29 东南大学 一种分子印迹纳米纤维增强基底膜的制备方法、应用及检测方法
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CN114295601B (zh) * 2021-12-31 2024-01-30 厦门大学 一种基于连续体束缚态的表面拉曼增强传感结构

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102265155A (zh) * 2008-11-10 2011-11-30 卢米耐克斯公司 用于制备和使用多重检测中的大孔珠粒的方法和体系
CN102265155B (zh) * 2008-11-10 2014-08-13 卢米耐克斯公司 用于制备和使用多重检测中的大孔珠粒的方法和体系
US8877511B2 (en) 2008-11-10 2014-11-04 Luminex Corporation Method and system for manufacture and use of macroporous beads in a multiplex assay
US9745438B2 (en) 2008-11-10 2017-08-29 Luminex Corporation Method and system for manufacture and use of macroporous beads in a multiplex assay
CN102811943A (zh) * 2009-12-11 2012-12-05 韩国化学研究院 拉曼活性分子位于纳米粒子二聚体的结合部的二聚体核壳纳米粒子、其用途及制备方法
CN102811943B (zh) * 2009-12-11 2015-08-19 韩国化学研究院 以位于粒子间的结合部的拉曼活性分子标记的二聚体核壳纳米结构、其用途及制备方法
CN102323412A (zh) * 2011-08-09 2012-01-18 中国科学院合肥物质科学研究院 一种拉曼编码微球的用途及利用拉曼编码微球检测肿瘤标志物的方法
CN102323412B (zh) * 2011-08-09 2014-01-01 中国科学院合肥物质科学研究院 一种拉曼编码微球的用途及利用拉曼编码微球检测肿瘤标志物的方法
CN109342392A (zh) * 2018-11-09 2019-02-15 中国科学院烟台海岸带研究所 一种以聚苯乙烯为包裹壳层材料的表面增强拉曼散射纳米探针及其制备方法

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US20050130163A1 (en) 2005-06-16
WO2004007767A2 (en) 2004-01-22
CA2492213C (en) 2013-02-12
JP2005533246A (ja) 2005-11-04
CN100413977C (zh) 2008-08-27
WO2004007767A3 (en) 2004-03-11
CA2492213A1 (en) 2004-01-22
EP1521846A2 (en) 2005-04-13
GB0216197D0 (en) 2002-08-21
HK1072960A1 (en) 2005-09-16
JP4754213B2 (ja) 2011-08-24
EP1521846B1 (en) 2013-03-06
AU2003281070B2 (en) 2008-01-24
AU2003281070A1 (en) 2004-02-02
CN1668764A (zh) 2005-09-14

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